Spero Ventures

Spero Ventures is a venture capital firm founded in 2018 and based in Burlingame, California. The firm focuses on making investments in companies that enhance well-being, work, purpose, and human connection. Spero Ventures concentrates on sectors including health and wellness, technology, and software or software-enabled hardware. As a Registered Investment Adviser, the firm seeks to support innovations that contribute positively to people's lives.

Sara Eshelman

General Partner

Shripriya Mahesh

Co-Founder and General Partner

Marc Tarpenning

Venture Partner

Brandon Walker

Investor

Stephen Wemple

Principal

Lisa Zieger

Partner, Community and Network

34 past transactions

Singularity Energy

Seed Round in 2022
Singularity Energy, Inc. is a company that develops a platform for real-time energy and carbon management, aimed at helping corporate clients optimize their energy usage and reduce carbon emissions. Founded in 2018 and based in Cambridge, Massachusetts, the company utilizes artificial intelligence to incorporate real-time carbon dioxide signals from the energy grid into its management solutions. This innovative approach allows organizations to co-optimize their energy costs and emissions effectively. Singularity Energy's platform is designed to support climate regulators and sustainability professionals by providing transparent and reliable data, thereby enabling informed decision-making to meet rigorous environmental targets. By offering a modern alternative to traditional carbon reporting methods, the company contributes to the broader goal of grid decarbonization and promotes sustainable practices in various industries.

Guide

Seed Round in 2022
Developer of a virtual recruiting platform designed to automate, measure and analyze candidate experience. The company's platform improves and measures candidate engagement, streamlines interview logistics as well and increases conversion rates, enabling clients to implement transparent hiring practices and job aspirants to find the right company for themselves.

Huckleberry Labs

Series A in 2021
Huckleberry Labs is focused on enhancing children's sleep by making behavioral expertise accessible and affordable for families. The company has developed an evidence-based program that combines artificial intelligence with human expertise. Their mobile application tracks a child's sleep patterns over a week, providing insights into their sleep conditions. Based on this data, the app offers a straightforward program for parents to help improve their children's sleep habits. Through this innovative approach, Huckleberry Labs aims to support families in addressing sleep challenges effectively.

Gencove

Series A in 2021
Gencove is a company focused on making genomics affordable and accessible through its innovative low-coverage whole genome sequencing technology. It has developed a sequencing platform that emphasizes speed, cost-effectiveness, and practical applications. By creating molecular and computational tools, Gencove enables high-throughput and low-cost genome sequencing across various industries, including agriculture and pharmaceuticals. This approach allows researchers to access valuable genomic data, facilitating advancements in their respective fields.

BIOMILQ

Series A in 2021
We leverage our patent-pending technology to produce nutritionally equivalent breastmilk from cultured human mammary cells. With Biomilq, families can achieve the recommended six months of exclusive breastfeeding while alleviating the climate impacts of bovine-based infant formula.

DroneSeed, Inc.

Series A in 2021
DroneSeed, Inc. is a Seattle-based company that specializes in reforestation services, providing innovative solutions to timber companies, non-profit organizations, and government agencies across the Northwest and Southeast United States. Established in 2015, DroneSeed utilizes advanced drone technology to plant tree seed vessels, apply fertilizers and herbicides, and gather field data. The company is notable for its pioneering achievements, having received multiple FAA approvals that allow it to operate heavy-lift drone swarms, each capable of carrying a 57-pound payload. This capability enables DroneSeed to enhance the scalability of reforestation efforts, which is essential for addressing carbon emissions. By charging clients on a per-acre basis for its services, DroneSeed aims to make a significant impact on environmental restoration and sustainable forestry practices.

AllHere

Series A in 2021
AllHere, Inc. is a Boston-based company that focuses on reducing chronic absenteeism in K-12 schools through its intervention management platform. The platform offers various tools, including referral management to analyze chronic absence data at multiple levels, intervention tracking applications for monitoring attendance interventions such as home visits and mentoring, and automated analytics reports to assess the effectiveness of intervention programs. Additionally, AllHere employs artificial intelligence and supervised machine learning to enhance its chatbot software, facilitating real-time, one-on-one communication between schools and families. This approach aims to create engaging experiences that support student recruitment, retention, and success by providing timely assistance and information to families.

Nana

Series A in 2021
Nana Services, Inc. is a technology-driven company specializing in appliance repair services, offering solutions for various household appliances such as refrigerators, dishwashers, ovens, and washers through its Nana Home platform. Founded in 2016 and headquartered in Alameda, California, the company addresses the growing demand for skilled tradespeople by providing a free online vocational school, known as Nano Academy, that equips individuals with hands-on repair skills. Graduates of this program are not only offered initial employment opportunities but are also supported in advancing their careers through Nana's AI-powered marketplace, which connects customers with qualified professionals. Through these initiatives, Nana aims to create a sustainable pipeline of skilled workers while addressing the challenges of unemployment and underemployment in the United States.

Hyro

Series A in 2021
Hyro is a technology company that specializes in developing conversational AI assistants for enterprises. Founded in 2014 and headquartered in New York, Hyro enables organizations to enhance user interaction on digital platforms through intuitive voice and chat capabilities. The company's innovative approach allows for seamless integration of AI into websites and mobile applications, significantly improving user engagement and conversion rates. Unlike traditional solutions, Hyro simplifies the deployment and maintenance of its technology by automatically generating a knowledge graph from existing content, eliminating the need for complex integration processes, playbooks, or extensive training data. This frictionless approach positions Hyro as a leader in the conversational AI space, making advanced technology accessible to a wide range of businesses.

Tortuga AgTech

Series A in 2021
Tortuga AgTech focuses on enhancing agricultural practices through the development of digital horticulture systems that integrate robotics, automation, precision data analytics, and machine learning. By automating labor-intensive tasks such as picking, packing, and trimming, Tortuga AgTech aims to significantly reduce the manual labor required in farming while increasing yields through optimized growing conditions. The company's mission is to promote a healthier society and a thriving ecosystem by empowering growers to produce unique, nutritious food that is environmentally sustainable. This approach not only helps farmers compete with large-scale agriculture but also fosters the creation of local technical jobs. Ultimately, Tortuga AgTech strives to provide fresher and healthier products to communities near their grower clients.

Talkshoplive

Seed Round in 2021
talkshoplive is the leading live stream commerce network and distribution vehicle with a patent-pending embeddable video player containing sales execution, allowing transactions to be processed within the video player anywhere it exists. The network and app offer a full range of services for both buyers and sellers - from live show creation to order processing, to ease of shipping and payouts.

BrainsGate

Series F in 2020
BrainsGate, Ltd., a medical device company, develops therapies for patients suffering from central nervous system (CNS) diseases. It offers a technology platform that involves electrical stimulation of the spheno-palatine ganglion (SPG), a nervous center known to increase cerebral blood flow. The company develops an ischemic stroke system that is based on an implantable electrode and is designed to deliver electrical stimulation to the spheno-palatine ganglion (SPG). Its system augments cerebral blood flow by using an external system temporarily attached to the patient’s cheek. BrainsGate, Ltd. was founded in 2000 and is based in Caesarea, Israel.

MetaMap

Series A in 2020
Mati enables builders in fast-growing, underserved regions with the digital identity tools they need to provide better trust-based services to more people. We're making starting this new type of 'Trust Economy' company as simple as setting up a store on Shopify.

MetaMap

Series A in 2020
Mati enables builders in fast-growing, underserved regions with the digital identity tools they need to provide better trust-based services to more people. We're making starting this new type of 'Trust Economy' company as simple as setting up a store on Shopify.

Nana

Seed Round in 2020
Nana Services, Inc. is a technology-driven company specializing in appliance repair services, offering solutions for various household appliances such as refrigerators, dishwashers, ovens, and washers through its Nana Home platform. Founded in 2016 and headquartered in Alameda, California, the company addresses the growing demand for skilled tradespeople by providing a free online vocational school, known as Nano Academy, that equips individuals with hands-on repair skills. Graduates of this program are not only offered initial employment opportunities but are also supported in advancing their careers through Nana's AI-powered marketplace, which connects customers with qualified professionals. Through these initiatives, Nana aims to create a sustainable pipeline of skilled workers while addressing the challenges of unemployment and underemployment in the United States.

Fiveable

Venture Round in 2020
Fiveable, Inc. is an educational technology company founded in 2018 and based in Milwaukee, Wisconsin. It operates an interactive social learning platform designed specifically for Advanced Placement (AP) students and teachers. The platform facilitates engagement through live-streamed lessons, interactive discussions, and supportive communities, allowing students to connect with peers and educators. Fiveable offers resources across various subjects, including history, social science, STEM, and languages, to enhance academic and social-emotional learning. By fostering collaboration and interaction, Fiveable aims to create a dynamic educational environment that supports both teaching and learning outside of traditional classroom settings.

Empowerly

Venture Round in 2020
Empowerly, Inc. provides college counseling and tutoring services. It serves 7th-12th grade, transfer, and graduate students. Empowerly, Inc. was formerly known as Synocate, Inc. The company is headquartered in San Mateo, California.

Skillshare

Series D in 2020
Skillshare, Inc. is an online learning community that connects creators from around the world. Founded in 2010 and based in New York, the platform offers a diverse range of classes covering topics such as illustration, design, photography, video, and freelancing. Users can participate in online classes, watch video lessons, engage in projects and workshops, and even teach their own classes. By providing access to thousands of courses, Skillshare empowers individuals to explore various skills, from baking to entrepreneurship, fostering creativity and personal development in an accessible format.

Huckleberry Labs

Seed Round in 2020
Huckleberry Labs is focused on enhancing children's sleep by making behavioral expertise accessible and affordable for families. The company has developed an evidence-based program that combines artificial intelligence with human expertise. Their mobile application tracks a child's sleep patterns over a week, providing insights into their sleep conditions. Based on this data, the app offers a straightforward program for parents to help improve their children's sleep habits. Through this innovative approach, Huckleberry Labs aims to support families in addressing sleep challenges effectively.

MetaMap

Seed Round in 2020
Mati enables builders in fast-growing, underserved regions with the digital identity tools they need to provide better trust-based services to more people. We're making starting this new type of 'Trust Economy' company as simple as setting up a store on Shopify.

Clarity Movement

Series A in 2020
Clarity Movement is a team of passionate engineers and scientists focused on making a positive impact in the world by tackling the global air pollution crisis. They leverage their expertise in air sensing technology, IoT devices, and data analytics to create solutions that empower communities to make more informed decisions and improve the quality of life. Having successfully developed the world’s most accurate low-cost particulate matter sensor, Clarity is now deploying the next generation of dense air quality monitoring networks around the world to build smarter cities through smarter data.

RushTix

Pre Seed Round in 2020
RushTix, Inc. is a subscription-based platform that focuses on live entertainment, including music, health, and comedy shows. Founded in 2014 and headquartered in San Francisco, California, the company aims to create a unique experience for fans by providing access to a diverse range of performances. RushTix is particularly dedicated to fostering connections between premier comedians and their audiences, enhancing the intimacy of live comedy through personal engagement. By offering a wide array of events, RushTix seeks to become a leading destination for fans who appreciate the thrill of live performances.

Base Operations

Seed Round in 2019
Base Operations Inc. is a company that specializes in providing street-level threat analysis services, primarily for global companies operating in emerging markets. Founded in 2016 and based in Cambridge, Massachusetts, the company offers a platform that aggregates and visualizes crime data through heat maps. Its solutions include detailed threat assessments, neighborhood ratings, and tools that assist security personnel in making informed location-based decisions. By leveraging micro-intelligence and crowdsourced data, Base Operations helps organizations enhance their operational safety, address supply chain risks, and ensure the security of their workforce. The platform also features AI-powered predictive analytics, enabling faster response times and improved decision-making for enterprise security.

INDUS.AI

Series A in 2019
indus.ai, Inc., a technology company, provides a construction Intelligence-as-a-Service software to organize chaos involving people, equipment, and materials in construction sites. It offers Indus.ai, an AI-enabled computer vision software platform that allows users to gain insights about their job sites; install cameras to provide images/videos from their site and the platform turns those into analytics and insights. The company’s solutions are used for developers, general contractors, owners, safety and compliance, and construction intelligence. indus.ai, Inc. was founded in 2017 and is based in San Francisco, California with an additional office in Thornhill, Canada.

Core

Seed Round in 2019
Core Wellness, Inc. is a San Francisco-based company focused on mental wellness through guided meditation. Established in 2015, it specializes in developing innovative meditation devices that utilize haptic feedback and biosensors to enhance the meditation experience. These devices are designed to help users connect more deeply, manage stress, relax, and improve sleep quality by providing personalized techniques and real-time feedback. Core's technology aims to simplify daily meditation practices, making it accessible and effective for individuals seeking to improve their mental well-being.

Tortuga AgTech

Venture Round in 2019
Tortuga AgTech focuses on enhancing agricultural practices through the development of digital horticulture systems that integrate robotics, automation, precision data analytics, and machine learning. By automating labor-intensive tasks such as picking, packing, and trimming, Tortuga AgTech aims to significantly reduce the manual labor required in farming while increasing yields through optimized growing conditions. The company's mission is to promote a healthier society and a thriving ecosystem by empowering growers to produce unique, nutritious food that is environmentally sustainable. This approach not only helps farmers compete with large-scale agriculture but also fosters the creation of local technical jobs. Ultimately, Tortuga AgTech strives to provide fresher and healthier products to communities near their grower clients.

Gencove

Series A in 2019
Gencove is a company focused on making genomics affordable and accessible through its innovative low-coverage whole genome sequencing technology. It has developed a sequencing platform that emphasizes speed, cost-effectiveness, and practical applications. By creating molecular and computational tools, Gencove enables high-throughput and low-cost genome sequencing across various industries, including agriculture and pharmaceuticals. This approach allows researchers to access valuable genomic data, facilitating advancements in their respective fields.

Huckleberry Labs

Pre Seed Round in 2019
Huckleberry Labs is focused on enhancing children's sleep by making behavioral expertise accessible and affordable for families. The company has developed an evidence-based program that combines artificial intelligence with human expertise. Their mobile application tracks a child's sleep patterns over a week, providing insights into their sleep conditions. Based on this data, the app offers a straightforward program for parents to help improve their children's sleep habits. Through this innovative approach, Huckleberry Labs aims to support families in addressing sleep challenges effectively.

ROAM

Series A in 2018
Roam Robotics, Inc. is a San Francisco-based company that specializes in the development of innovative exoskeletons and powered orthotics. Founded in 2014, the company aims to make these mobility devices more affordable, comfortable, and safe for home use. Roam's products utilize advanced high-strength fabrics and pneumatic powertrains, which significantly reduce the weight and cost compared to traditional exoskeleton designs. This approach allows for unmatched power-to-weight ratios, enhancing performance while minimizing part count. The company's focus on lightweight and adaptable robotic solutions aims to improve mobility support, ultimately enhancing human capabilities for a wide range of users.

SafeTraces

Series A in 2018
SafeTraces provides on-food traceability solutions that trace the product, not the package. Edible, invisible, odorless, tasteless, FDA approved barcodes are applied to fresh or processed foods, pharmaceuticals, and many other commodities. The barcodes carry complete traceability information across the supply chain. SafeTraces also has wide applicability in environmental monitoring, healthcare, and other industries.

RevUp.

Series A in 2018
RevUp Software specializes in providing advanced predictive data analytics tailored for fundraising efforts within non-profits, academic institutions, and political organizations. The company's platform enhances the abilities of fundraisers by offering innovative methods to identify, target, and engage their networks. By integrating seamlessly with existing software, RevUp empowers organizations to leverage data analytics and social media effectively, enabling them to achieve and surpass their fundraising objectives.

INDUS.AI

Seed Round in 2018
indus.ai, Inc., a technology company, provides a construction Intelligence-as-a-Service software to organize chaos involving people, equipment, and materials in construction sites. It offers Indus.ai, an AI-enabled computer vision software platform that allows users to gain insights about their job sites; install cameras to provide images/videos from their site and the platform turns those into analytics and insights. The company’s solutions are used for developers, general contractors, owners, safety and compliance, and construction intelligence. indus.ai, Inc. was founded in 2017 and is based in San Francisco, California with an additional office in Thornhill, Canada.

Skillshare

Series C in 2018
Skillshare, Inc. is an online learning community that connects creators from around the world. Founded in 2010 and based in New York, the platform offers a diverse range of classes covering topics such as illustration, design, photography, video, and freelancing. Users can participate in online classes, watch video lessons, engage in projects and workshops, and even teach their own classes. By providing access to thousands of courses, Skillshare empowers individuals to explore various skills, from baking to entrepreneurship, fostering creativity and personal development in an accessible format.

DroneSeed, Inc.

Venture Round in 2017
DroneSeed, Inc. is a Seattle-based company that specializes in reforestation services, providing innovative solutions to timber companies, non-profit organizations, and government agencies across the Northwest and Southeast United States. Established in 2015, DroneSeed utilizes advanced drone technology to plant tree seed vessels, apply fertilizers and herbicides, and gather field data. The company is notable for its pioneering achievements, having received multiple FAA approvals that allow it to operate heavy-lift drone swarms, each capable of carrying a 57-pound payload. This capability enables DroneSeed to enhance the scalability of reforestation efforts, which is essential for addressing carbon emissions. By charging clients on a per-acre basis for its services, DroneSeed aims to make a significant impact on environmental restoration and sustainable forestry practices.
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