HeMemics Biotechnologies
Venture Round in 2025
HeMemics Biotechnologies Inc. is a privately held biosensor company based in Gaithersburg, Maryland, specializing in the research and development of diagnostic test platforms for detecting bacterial and viral pathogens. The company's innovative technology utilizes an electronic chip to determine the presence or absence of pathogens from aqueous samples. HeMemics is finalizing a unique testing platform that combines near PCR-level accuracy with the cost-effectiveness of lateral-flow tests, enabling simultaneous detection of antibodies, antigens, and small molecule targets. This platform features a robust, low-cost handheld reader and a disposable biosensor capable of identifying up to 32 pathogens using patented desiccation technology. The rapid point-of-care tool delivers results in under five minutes and can be integrated wirelessly with cloud-based data analytics to monitor emerging health threats. Its applications extend beyond public health to include defense and national security sectors. HeMemics Biotechnologies was incorporated in 2009.
Pathotrak
Venture Round in 2025
Pathotrak, LLC, founded in 2016 and based in College Park, Maryland, develops innovative food safety testing kits that significantly enhance the detection of food-borne pathogens, such as Salmonella and E. coli. Utilizing advanced microfiltration technology, Pathotrak's kits reduce the testing time from 1-2 days to just 6 hours, streamlining the traditional 22-hour enrichment process. This rapid detection capability not only ensures compliance with FDA and USDA regulations but also integrates seamlessly into existing detection systems. By minimizing holding times and associated costs, as well as enabling quicker product releases, Pathotrak's technology aims to transform food safety practices and logistics in the industry, ultimately helping to prevent dangerous outbreaks and improve overall food safety.
Novel Microdevices
Venture Round in 2025
Novel Microdevices, LLC is focused on developing handheld devices for molecular diagnostics, specifically through its product, NOVEL DX. This innovative device utilizes microfluidics technology to analyze raw biological samples directly at the point of care, providing results in just 30 minutes. By enabling healthcare professionals to achieve lab-quality results without the need for a traditional laboratory setting, the device addresses various sectors including clinical diagnostics, biodefense, food safety, forensics, drug discovery, animal care, and agriculture. Founded in 2014 by Andrea Pais, Novel Microdevices is headquartered in Baltimore, Maryland.
Impruvon Health
Seed Round in 2025
Impruvon Health is dedicated to enhancing the health of individuals who struggle with complex medication regimens, particularly those living at home or in long-term care settings. The company focuses on specific populations, including individuals with intellectual and developmental disabilities, those in recovery from addiction, and veterans. Its medical technology platform automates medication management by streamlining storage, administration, and record-keeping processes. This system features smart alerts and reminders, as well as live notifications of unauthorized access attempts, tailored to meet the unique needs of each user. By addressing the serious consequences of medication errors, Impruvon Health aims to improve medication compliance and promote independence and security for individuals and their caregivers.
NanoBioFAB
Pre Seed Round in 2025
Nanobiofab, founded in 2015 and based in Frederick, Maryland, specializes in the development of wearable, smart healthcare and medical devices utilizing nanotechnology for both humans and pets. The company is known for its product, iNose, which enables users to detect, track, and monitor their body's skin vapor-print. This device wirelessly connects to mobile phones to help individuals assess their fat burning rate and evaluate the effectiveness of their exercise routines. Additionally, it provides insights into the effects of dietary choices over time and tracks metabolic rates. Beyond consumer products, Nanobiofab also offers technology and services aimed at accelerating nanomaterial research and development, including nanoprinting solutions and artificial intelligence sensors for telemedicine and personalized healthcare applications.
NextStep Robotics
Seed Round in 2024
NextStep Robotics Inc. is focused on developing innovative solutions for treating foot drop through a robotic device that enhances walking function. Incorporated in 2017 and based in Baltimore, Maryland, the company enables clinics to offer personalized robotic therapy using adaptive software that provides assistance tailored to each patient's needs. This system allows lower-skilled clinic staff to operate the device, thereby freeing up therapists to concentrate on other treatment modalities. As the company collects more data, the software will evolve into an AI-based system that optimizes training protocols for individual patients. The device is classified as a Class 1 Exercise Device, which allows for immediate revenue generation through direct sales, leasing, software subscriptions, and service contracts. This clinically proven approach not only improves patient outcomes but also enables clinics to provide reimbursable therapy for conditions that previously lacked effective treatment options.
JuneBrain, LLC is a Washington, D.C.-based company founded in 2017 that focuses on developing wearable and non-invasive imaging devices for multiple sclerosis patients. The technology allows patients to monitor their disease activity from home, facilitating earlier detection of MS attacks and enhancing the monitoring of treatment efficacy. By leveraging telemedicine, JuneBrain aims to optimize remote assessment for neurological diseases, thereby enabling clinicians to track patients outside traditional clinical settings. The company's long-term vision includes extending its device's applications to a broader range of neurodegenerative diseases, promoting more accessible and frequent monitoring of brain health.
Sonogen
Seed Round in 2024
Sonogen Medical is a medical device company developing an ultrasonic bone fracture healing technology. This non-invasive device accelerates bone repair and reduces healing time by delivering low-intensity pulsed ultrasound, stimulating bone growth. Targeting the 8-10% of patients with improper bone fracture healing, Sonogen aims to address a $1.7 billion annual market.
Sisu Global Health
Seed Round in 2023
Sisu Global Health develops a handheld mechanical device designed to salvage, filter, and recycle blood from patients experiencing internal bleeding. This innovative medical device allows physicians to collect blood from internal hemorrhages during surgical procedures, providing an alternative to donor blood in emergency situations such as blunt trauma and complications during pregnancy. By enabling intraoperative autotransfusion, Sisu Global Health's technology aims to enhance patient outcomes and streamline blood management in critical care scenarios.
Linshom is focused on providing continuous respiratory monitoring solutions that include measurements of Tidal Volume at the patient's bedside or in home settings. The company has developed a wearable sensor that is FDA cleared, designed to enable continuous, predictive respiratory monitoring. This technology allows for early detection of respiratory decline, which can help prevent costly rapid response situations, ICU transfers, and potential fatalities. By addressing a critical unmet medical need, Linshom aims to enhance patient care and improve outcomes through advanced respiratory monitoring capabilities.
NanoBioFAB
Pre Seed Round in 2023
Nanobiofab, founded in 2015 and based in Frederick, Maryland, specializes in the development of wearable, smart healthcare and medical devices utilizing nanotechnology for both humans and pets. The company is known for its product, iNose, which enables users to detect, track, and monitor their body's skin vapor-print. This device wirelessly connects to mobile phones to help individuals assess their fat burning rate and evaluate the effectiveness of their exercise routines. Additionally, it provides insights into the effects of dietary choices over time and tracks metabolic rates. Beyond consumer products, Nanobiofab also offers technology and services aimed at accelerating nanomaterial research and development, including nanoprinting solutions and artificial intelligence sensors for telemedicine and personalized healthcare applications.
HeMemics Biotechnologies
Seed Round in 2023
HeMemics Biotechnologies Inc. is a privately held biosensor company based in Gaithersburg, Maryland, specializing in the research and development of diagnostic test platforms for detecting bacterial and viral pathogens. The company's innovative technology utilizes an electronic chip to determine the presence or absence of pathogens from aqueous samples. HeMemics is finalizing a unique testing platform that combines near PCR-level accuracy with the cost-effectiveness of lateral-flow tests, enabling simultaneous detection of antibodies, antigens, and small molecule targets. This platform features a robust, low-cost handheld reader and a disposable biosensor capable of identifying up to 32 pathogens using patented desiccation technology. The rapid point-of-care tool delivers results in under five minutes and can be integrated wirelessly with cloud-based data analytics to monitor emerging health threats. Its applications extend beyond public health to include defense and national security sectors. HeMemics Biotechnologies was incorporated in 2009.
SeeTrue Technology
Non Equity Assistance in 2023
SeeTrue Technology specializes in the development of innovative microcapillary devices aimed at enhancing precision in microinjection procedures within the biomedical field. The company's advanced injection needles significantly reduce issues such as clogging, cell adherence, and tissue damage, while improving tip visibility and enabling directional targeted injections. By addressing critical challenges in microinjection technology, SeeTrue's solutions facilitate more reliable and efficient procedures, ultimately enhancing the reproducibility of outcomes for customers in various biomedical applications.
Kubanda Cryotherapy
Non Equity Assistance in 2023
Kubanda Cryotherapy specializes in providing minimally invasive, non-surgical treatments for lumps, bumps, and cancers in pets. The company has developed a custom-designed cryosystem that includes a cryoprobe and a gas-control module, allowing for precise temperature modulation. This innovative system employs freezing cycles that have been proven effective in shrinking and killing tumors. By offering a point-of-care solution, Kubanda Cryotherapy enables veterinarians and pet owners to access quality care for their pets without the need for surgical interventions.
Djit Medtech
Non Equity Assistance in 2023
Djit Medtech is focused on developing innovative solutions for patients suffering from advanced hand arthritis. The company is creating a finger joint implant device designed to relieve pain and preserve movement in affected individuals. By enabling joint replacements for fingers to become as routine and reliable as those for knees and hips, Djit Medtech aims to improve the quality of life for arthritis patients.
SeeTrue Technology
Pre Seed Round in 2023
SeeTrue Technology specializes in the development of innovative microcapillary devices aimed at enhancing precision in microinjection procedures within the biomedical field. The company's advanced injection needles significantly reduce issues such as clogging, cell adherence, and tissue damage, while improving tip visibility and enabling directional targeted injections. By addressing critical challenges in microinjection technology, SeeTrue's solutions facilitate more reliable and efficient procedures, ultimately enhancing the reproducibility of outcomes for customers in various biomedical applications.
Linshom
Venture Round in 2022
Linshom is focused on providing continuous respiratory monitoring solutions that include measurements of Tidal Volume at the patient's bedside or in home settings. The company has developed a wearable sensor that is FDA cleared, designed to enable continuous, predictive respiratory monitoring. This technology allows for early detection of respiratory decline, which can help prevent costly rapid response situations, ICU transfers, and potential fatalities. By addressing a critical unmet medical need, Linshom aims to enhance patient care and improve outcomes through advanced respiratory monitoring capabilities.
Lasarrus
Pre Seed Round in 2022
Lasarrus is a Baltimore-based company founded in 2013 that specializes in developing wearable devices for patients with chronic obstructive pulmonary disease (COPD). The company's innovative device is designed to enhance physical therapy by facilitating telemedicine and remote monitoring. It captures physiological and range-of-motion data, allowing patients to track their health routines effectively. Lasarrus aims to provide an affordable, comfortable, and non-invasive solution that accelerates recovery for users, improving their overall health management.
NanoBioFAB
Convertible Note in 2022
Nanobiofab, founded in 2015 and based in Frederick, Maryland, specializes in the development of wearable, smart healthcare and medical devices utilizing nanotechnology for both humans and pets. The company is known for its product, iNose, which enables users to detect, track, and monitor their body's skin vapor-print. This device wirelessly connects to mobile phones to help individuals assess their fat burning rate and evaluate the effectiveness of their exercise routines. Additionally, it provides insights into the effects of dietary choices over time and tracks metabolic rates. Beyond consumer products, Nanobiofab also offers technology and services aimed at accelerating nanomaterial research and development, including nanoprinting solutions and artificial intelligence sensors for telemedicine and personalized healthcare applications.
CoolTech Medical
Seed Round in 2022
CoolTech Medical is a Baltimore-based company that specializes in transnasal cooling technology aimed at non-invasive fever control and neuroprotection. Founded in 2011, the company has developed the CoolStat device, which is compact, lightweight, and portable, allowing it to be easily transported throughout a hospital with the patient. This innovative device works by delivering filtered, room-temperature air through single-use tubing into the patient's nasal passages, creating an evaporative cooling effect that helps manage body temperature. The technology is particularly beneficial for patients experiencing cardiac arrest or head injuries, as it facilitates rapid cooling to improve outcomes.
Opal HTM
Seed Round in 2022
Opal HTM is a company focused on enhancing hospital safety and efficiency through innovative medical equipment management solutions. It has developed a healthcare equipment inventory management platform that aims to maximize the return on investment in technology. By optimizing procurement and maintenance strategies, Opal HTM helps healthcare managers improve workflows and plan effectively for the future. The platform provides unprecedented clarity, allowing for better management of equipment inventories, which ultimately enhances the overall effectiveness and efficiency of healthcare operations.
Tomorrow's Bio Today
Grant in 2022
Tomorrow's Bio Today specializes in developing innovative medical devices for the veterinary sector, focusing on enhancing diagnostic procedures for large animals such as cows and horses. The company has created ingestible tablet cameras that capture images of the gastrointestinal tract, transmitting this data to a mobile application. This technology offers a safer, more cost-effective alternative to traditional colonoscopy and endoscopy methods, allowing veterinarians and farmers to obtain detailed insights into the health of large animals. By improving the efficiency and safety of diagnostic processes, Tomorrow's Bio Today aims to facilitate early detection of health issues, including colorectal cancer, thereby supporting better animal care and management.
ExPulsus creates a blood pressure monitoring device for critical care patients that employs a revolutionary pressure sensing technique that is non-invasive, has a minimal risk of complications, and is a low-cost method of monitoring sick ICU patients.
Intraderm is developing a medical device to address Wrong Site Surgery, a difficulty in the treatment of skin cancer.
Nanobiofab, founded in 2015 and based in Frederick, Maryland, specializes in the development of wearable, smart healthcare and medical devices utilizing nanotechnology for both humans and pets. The company is known for its product, iNose, which enables users to detect, track, and monitor their body's skin vapor-print. This device wirelessly connects to mobile phones to help individuals assess their fat burning rate and evaluate the effectiveness of their exercise routines. Additionally, it provides insights into the effects of dietary choices over time and tracks metabolic rates. Beyond consumer products, Nanobiofab also offers technology and services aimed at accelerating nanomaterial research and development, including nanoprinting solutions and artificial intelligence sensors for telemedicine and personalized healthcare applications.
CarrTech
Seed Round in 2021
CarrTech is a medical device company focused on improving the safety and efficiency of medication preparation. It has developed and patented an integrated, all-in-one filter and hypodermic needle system specifically designed for filtering medications stored in glass ampoules. This innovative solution replaces the traditional multi-step process, offering a single-step, one-needle approach that enhances safety and reduces costs for users. By streamlining the filtering process, CarrTech aims to provide a more effective method for administering ampoule-based medications, ultimately improving patient care and operational efficiency in medical settings.
CarrTech is a medical device company focused on improving the safety and efficiency of medication preparation. It has developed and patented an integrated, all-in-one filter and hypodermic needle system specifically designed for filtering medications stored in glass ampoules. This innovative solution replaces the traditional multi-step process, offering a single-step, one-needle approach that enhances safety and reduces costs for users. By streamlining the filtering process, CarrTech aims to provide a more effective method for administering ampoule-based medications, ultimately improving patient care and operational efficiency in medical settings.
JuneBrain, LLC is a Washington, D.C.-based company founded in 2017 that focuses on developing wearable and non-invasive imaging devices for multiple sclerosis patients. The technology allows patients to monitor their disease activity from home, facilitating earlier detection of MS attacks and enhancing the monitoring of treatment efficacy. By leveraging telemedicine, JuneBrain aims to optimize remote assessment for neurological diseases, thereby enabling clinicians to track patients outside traditional clinical settings. The company's long-term vision includes extending its device's applications to a broader range of neurodegenerative diseases, promoting more accessible and frequent monitoring of brain health.
Vixiar Medical, Inc., established in 2013 and headquartered in Annapolis, Maryland, specializes in developing non-invasive, cost-effective devices and systems for monitoring cardiopulmonary diseases. Its flagship product, Indicor, is a handheld, point-of-care device and digital platform designed to monitor worsening heart failure. Vixiar's devices aim to improve clinical workflow and deliver economic value to the healthcare system by enabling assessments of cardiac filling pressure in various settings, including homes, physician offices, nursing homes, and hospitals.
ReGelTec
Venture Round in 2018
ReGelTec, Inc. is a medical device company based in Baltimore, Maryland, focused on developing minimally invasive spinal implants aimed at treating lower back pain and degenerative disc disease. Established in 2018, the company has created a unique device that is injected into the nucleus of an intervertebral disc using a small needle. This viscous solution is filled to a predetermined height or pressure, solidifying as it cools to body temperature, which helps alleviate pain without the need for follow-up surgery. ReGelTec's innovative approach offers a potential solution for patients suffering from debilitating spinal conditions.
CoapTech
Seed Round in 2018
CoapTech, Inc. is a medical device company based in Baltimore, Maryland, specializing in ultrasound-based solutions for the placement of feeding tubes. Founded in 2016, CoapTech has developed the Point-of-care Ultrasound Magnet Aligned (PUMA-G) System, which mitigates risks associated with traditional methods such as PEG blind sticks, endoscope reprocessing, and fluoroscopy by allowing for ultrasound visualization from the stomach wall to the surface. The company also offers a procedure known as Percutaneous Ultrasound Gastrostomy (PUG), designed for critical care physicians and non-surgical providers to simplify the insertion of gastrostomy tubes. Utilizing a proprietary technology called Coaptive Ultrasound, CoapTech combines magnetic device guidance with real-time ultrasound feedback, aiming to improve safety, reduce healthcare costs, and enhance patient care experiences. Their focus on the PUG procedure highlights a commitment to innovation, safety, and accessibility in medical care delivery across various patient populations.
Nanobiofab, founded in 2015 and based in Frederick, Maryland, specializes in the development of wearable, smart healthcare and medical devices utilizing nanotechnology for both humans and pets. The company is known for its product, iNose, which enables users to detect, track, and monitor their body's skin vapor-print. This device wirelessly connects to mobile phones to help individuals assess their fat burning rate and evaluate the effectiveness of their exercise routines. Additionally, it provides insights into the effects of dietary choices over time and tracks metabolic rates. Beyond consumer products, Nanobiofab also offers technology and services aimed at accelerating nanomaterial research and development, including nanoprinting solutions and artificial intelligence sensors for telemedicine and personalized healthcare applications.
ARMR Systems
Seed Round in 2018
ARMR Systems LLC, based in Baltimore, Maryland, specializes in the development of wearable hemorrhage control systems aimed at enhancing the survivability of traumatic injuries in battlefield scenarios where immediate medical support is unavailable. Founded in 2014, the company offers standalone products and integrated solutions that provide combat medics and field personnel with effective trauma care capabilities. Its systems include an ergonomically designed harness combined with a tourniquet-style device that delivers rapid compression to critical areas of the body, helping to restrict blood loss during emergencies. ARMR Systems emphasizes collaboration across various institutions and employs a multi-disciplinary team to ensure diverse perspectives are considered in their innovative approach to trauma care technology.
NextStep Robotics
Seed Round in 2018
NextStep Robotics Inc. is focused on developing innovative solutions for treating foot drop through a robotic device that enhances walking function. Incorporated in 2017 and based in Baltimore, Maryland, the company enables clinics to offer personalized robotic therapy using adaptive software that provides assistance tailored to each patient's needs. This system allows lower-skilled clinic staff to operate the device, thereby freeing up therapists to concentrate on other treatment modalities. As the company collects more data, the software will evolve into an AI-based system that optimizes training protocols for individual patients. The device is classified as a Class 1 Exercise Device, which allows for immediate revenue generation through direct sales, leasing, software subscriptions, and service contracts. This clinically proven approach not only improves patient outcomes but also enables clinics to provide reimbursable therapy for conditions that previously lacked effective treatment options.
Linshom
Seed Round in 2017
Linshom is focused on providing continuous respiratory monitoring solutions that include measurements of Tidal Volume at the patient's bedside or in home settings. The company has developed a wearable sensor that is FDA cleared, designed to enable continuous, predictive respiratory monitoring. This technology allows for early detection of respiratory decline, which can help prevent costly rapid response situations, ICU transfers, and potential fatalities. By addressing a critical unmet medical need, Linshom aims to enhance patient care and improve outcomes through advanced respiratory monitoring capabilities.
xMD Diagnostics
Seed Round in 2017
xMD Diagnostics, based in Annapolis, Maryland, specializes in biotechnology within the healthcare sector. The company develops molecular diagnostics tools that use high-throughput microdissection technology to improve cancer diagnosis and management. These tools are designed to isolate, procure, and enrich cells of interest from biopsy and other specimen samples. This process facilitates various downstream analyses, including PCR, genomic or proteomic testing, and next-generation sequencing. By enhancing the capabilities of clinical and research laboratories, xMD Diagnostics supports pathologists, oncologists, and other healthcare professionals in diagnosing, monitoring, and treating patients with cancer and serious genetic diseases.
Vixiar Medical, Inc., established in 2013 and headquartered in Annapolis, Maryland, specializes in developing non-invasive, cost-effective devices and systems for monitoring cardiopulmonary diseases. Its flagship product, Indicor, is a handheld, point-of-care device and digital platform designed to monitor worsening heart failure. Vixiar's devices aim to improve clinical workflow and deliver economic value to the healthcare system by enabling assessments of cardiac filling pressure in various settings, including homes, physician offices, nursing homes, and hospitals.
Sonavex, Inc. is a Baltimore-based company founded in 2013 that specializes in advanced imaging technology aimed at enhancing surgical outcomes. The company has developed a proprietary ultrasound-based platform that enables clinicians to detect anastomotic blood clots and assess critical intravascular flow metrics directly at the point of care. This technology not only facilitates the measurement of blood flow and vessel morphology but also includes bioresorbable and echogenic equipment to mark at-risk blood vessels for future assessments. By providing actionable data, Sonavex supports healthcare providers in monitoring and improving patient care, particularly in the context of post-operative complications.
Cordex Systems
Series A in 2017
Cordex Systems designs and manufactures a cardiovascular diagnostic device. Its product includes the Cordex EnDys System is a diagnostic tool that provides both early detection and ongoing monitoring of cardiovascular disease by measuring endothelial dysfunction.
Otomagnetics
Seed Round in 2016
Otomagnetics, Inc., based in Rockville, Maryland, develops a magnetic injection delivery system aimed at providing non-invasive drug delivery to challenging areas of the body, including the inner and middle ear, the eye, and the skin. Founded in 2012 as a spin-out from the University of Maryland College Park, the company addresses the difficulty of delivering therapies to the inner ear, which is shielded by the blood-labyrinth barrier. In preclinical studies, Otomagnetics' proprietary technology has successfully demonstrated the ability to deliver therapeutic agents to the inner ear, enhancing dosing and efficacy in models of tinnitus and noise-induced hearing loss. Additionally, the system has shown promise for treating middle ear conditions, such as otitis media, without the need for invasive procedures. While Otomagnetics' products are still experimental and not yet approved for human use, they represent a significant advancement in the field of targeted drug delivery.
Fusiform Medical
Seed Round in 2016
Fusiform, Inc. specializes in developing software solutions for the design and fabrication of orthotic devices. Its platform allows users to scan, generate, and annotate 3D models, facilitating the scheduling of patient appointments for clinicians and enabling vendors to manage orders and collaborate with customers. The software supports a wide range of products, including orthoses and prostheses, effectively streamlining the orthopedic device supply chain from patient assessment to manufacturing. Founded in 2015, Fusiform, Inc. is headquartered in Oakland, Maryland.
Rehabtics
Seed Round in 2013
Rehabtics is a scalable online game-based physical rehabilitation system for institutional and residential use. The system enables its patients to conduct physical therapy by playing motion-controlled video games at the convenience of their homes with automatic feedback and guidance. Rehabtics was launched in 2012 by Xiaoxu Kang and is operated from Baltimore, Maryland.