Telegraph Hill Partners

Telegraph Hill Partners is a venture capital firm established in 2001 and headquartered in San Francisco, California. The firm specializes in investing in technology-driven companies within the life sciences, medical devices, and healthcare sectors. Its investment focus includes pharmaceuticals, biotechnology, diagnostics, healthcare information technology, and various other areas related to healthcare innovation. As a Registered Investment Adviser, Telegraph Hill Partners aims to support technology leaders that are transforming the healthcare landscape through advanced solutions and innovations.

Rob Capone

Partner

Alex Efron

Senior Associate

Paul Grossman

Partner

Alexander C. Herzick

Partner

Deval A. Lashkari

Senior Partner

J. Matthew Mackowski

Chairman, Managing Director, Co-Founder

Glenn Novotny

Operating Partner

44 past transactions

Argonaut Manufacturing Services

Series A in 2024
Argonaut Manufacturing Services specializes in contract manufacturing for the biopharmaceutical, diagnostics, and life sciences sectors. The company offers a comprehensive suite of services, including high-yield aseptic fill/finish, reagent formulation, filling, kitting, lyophilization, and analytical support. By providing these essential services, Argonaut enables its clients to meet diverse outsourcing needs and efficiently produce a wide range of diagnostics and drug products.

Cell Microsystems

Series B in 2023
Cell Microsystems, Inc. is a biotechnology company based in Research Triangle Park, North Carolina, that focuses on developing, manufacturing, and commercializing innovative tools for single-cell biology. Founded in 2010, the company is known for its proprietary CellRaft™ Technology, which allows for the efficient sorting and isolation of single cells under standard culture conditions, preserving their unperturbed phenotypes and high viability. This technology is complemented by an automated imaging platform, enabling real-time selection and tracking of individual cells throughout imaging, collection, and downstream analysis. By facilitating single-cell isolation from small and valuable samples, Cell Microsystems provides scalable solutions that make advanced cell separation technology accessible to laboratories, enhancing the capabilities of researchers in single-cell research and genomics.

Panome Bio

Venture Round in 2023
Panome Bio is a biomarker discovery platform based in Saint Louis, Missouri, established in 2022. The company focuses on metabolomics technologies that facilitate biomarker discovery and metabolite profiling. Its services include metabolomics, lipidomics, and proteomics screening through untargeted analysis and proprietary computational methods. Panome Bio offers comprehensive workflows and personalized data analysis reports, enabling clients to gain a global and unbiased view of the metabolome, which encompasses a wide range of diverse metabolites in biological systems.

Emerging Therapy Solutions

Venture Round in 2022
Emerging Therapy Solutions, Inc. specializes in the outsourced management of cell and gene therapy treatments for healthcare payers. Founded in 2018 and based in Bloomington, Minnesota, the company provides a comprehensive suite of services, including patient management, data collection, analysis, reporting, and claims administration. Additionally, it develops proprietary algorithms to enhance the targeting and segmentation of rare conditions, facilitating the management of complex therapies. By leveraging a predictive intelligence platform, Emerging Therapy Solutions aims to streamline the administration of emerging therapies, thereby simplifying processes for healthcare providers.

Mosaic Biosciences

Venture Round in 2022
Mosaic Biosciences, Inc. specializes in developing biomaterials for tissue engineering and various medical applications, including drug delivery, regenerative medicine, and stem cell therapies. The company offers a technology platform that supports the incorporation of biological factors such as proteins, peptides, and nucleic acids, facilitating research and development in protein and antibody therapeutics. Mosaic Biosciences collaborates strategically with other organizations, such as Catalyst Biosciences, to enhance its capabilities. Founded in 2009 and based in Boulder, Colorado, the company aims to accelerate the drug discovery process by transforming concepts into development candidates, ultimately improving treatment options for patients.

Excellos

Funding Round in 2022
Excellos is a developer and manufacturer specializing in cell and gene therapies aimed at advancing innovative treatments. The company focuses on the development and clinical manufacturing of therapies such as CAR-T, tumor-infiltrating lymphocyte therapy, and immunotherapy. By providing cGMP cellular products and services, Excellos supports scientists and physicians in the field of advanced therapies, helping them harness the full potential of these powerful treatments. The company's expertise in process development and manufacturing is designed to accelerate the availability of these life-saving medications, establishing a new benchmark in the industry for cellular therapies.

Cell Microsystems

Venture Round in 2021
Cell Microsystems, Inc. is a biotechnology company based in Research Triangle Park, North Carolina, that focuses on developing, manufacturing, and commercializing innovative tools for single-cell biology. Founded in 2010, the company is known for its proprietary CellRaft™ Technology, which allows for the efficient sorting and isolation of single cells under standard culture conditions, preserving their unperturbed phenotypes and high viability. This technology is complemented by an automated imaging platform, enabling real-time selection and tracking of individual cells throughout imaging, collection, and downstream analysis. By facilitating single-cell isolation from small and valuable samples, Cell Microsystems provides scalable solutions that make advanced cell separation technology accessible to laboratories, enhancing the capabilities of researchers in single-cell research and genomics.

Carterra

Venture Round in 2020
Carterra, Inc. specializes in developing and commercializing innovative biomolecular interaction analysis solutions, primarily utilizing label-free technologies. The company offers a range of products, including its MultipleX 96 array-based surface plasmon resonance (SPR) imaging system and the Continuous Flow Microspotter (CFM), which is designed for high-throughput microarray printing. Carterra's services encompass epitope binning and mapping, first-pass kinetics, and assay development, catering to the needs of pharmaceutical and biotechnology clients. Its advanced platforms enable users to conduct kinetic and epitope analysis, supporting the rapid screening of antibodies and identification of potential therapeutic candidates. Founded in 2005 and headquartered in Salt Lake City, Utah, Carterra has additional offices in California, Massachusetts, and Germany, and distributes its products globally, including in China and Japan.

Nivagen Pharmaceuticals

Venture Round in 2020
Nivagen Pharmaceuticals, Inc. is focused on the development, acquisition, and sales of generic prescription drugs and over-the-counter products for the North American market. Founded in 2009 and based in Sacramento, California, the company aims to deliver high-quality products at affordable prices by forming partnerships with FDA-approved manufacturing facilities globally. Nivagen's products are distributed through various channels, including chain drug stores, regional wholesalers, mass merchandisers, hospitals, and mail order pharmacies. The company strategically positions itself within a growing market, as a significant volume of prescription products is set to go off patent in the coming years, creating opportunities for cost savings and value throughout the supply chain.

Carterra

Venture Round in 2020
Carterra, Inc. specializes in developing and commercializing innovative biomolecular interaction analysis solutions, primarily utilizing label-free technologies. The company offers a range of products, including its MultipleX 96 array-based surface plasmon resonance (SPR) imaging system and the Continuous Flow Microspotter (CFM), which is designed for high-throughput microarray printing. Carterra's services encompass epitope binning and mapping, first-pass kinetics, and assay development, catering to the needs of pharmaceutical and biotechnology clients. Its advanced platforms enable users to conduct kinetic and epitope analysis, supporting the rapid screening of antibodies and identification of potential therapeutic candidates. Founded in 2005 and headquartered in Salt Lake City, Utah, Carterra has additional offices in California, Massachusetts, and Germany, and distributes its products globally, including in China and Japan.

Akoya Biosciences

Series D in 2019
Akoya Biosciences is a spatial biology company offering the most comprehensive, end-to-end solutions for high-parameter tissue analysis from discovery through clinical and translational research, enabling the development of more precise therapies for immuno-oncology and other drug development applications. The company has two industry-leading platforms that empower investigators and researchers to gain a deeper understanding of complex diseases such as cancer, and autoimmune or neurological disorders. The CODEX system is the only benchtop platform that can efficiently quantify more than 40 biomarkers and is ideally suited for biomarker discovery. The Phenoptics platform is the only end-to-end multiplexed immunofluorescence solution with the robustness and high throughput necessary for translational research and clinical trials.

Specific Diagnostics

Venture Round in 2019
Specific Diagnostics, LLC is a medical device company based in West Palm Beach, Florida, founded in 2011. The company specializes in developing solutions for the detection, identification, and antibiotic susceptibility testing of pathogens. Its flagship product, the Specific Reveal system, utilizes patented technology that incorporates a low-cost small molecule sensor. This system is designed to streamline workflows in clinical settings and accelerate the time required to obtain diagnostic results, ultimately enhancing patient care by providing timely and specific treatment options.

Emerging Therapy Solutions

Venture Round in 2019
Emerging Therapy Solutions, Inc. specializes in the outsourced management of cell and gene therapy treatments for healthcare payers. Founded in 2018 and based in Bloomington, Minnesota, the company provides a comprehensive suite of services, including patient management, data collection, analysis, reporting, and claims administration. Additionally, it develops proprietary algorithms to enhance the targeting and segmentation of rare conditions, facilitating the management of complex therapies. By leveraging a predictive intelligence platform, Emerging Therapy Solutions aims to streamline the administration of emerging therapies, thereby simplifying processes for healthcare providers.

Nimble Therapeutics

Series A in 2019
Nimble Therapeutics is a biotechnology company focused on drug discovery through its innovative maskless chemical synthesis platform. This technology allows for the systematic synthesis and discovery of novel medicines across various therapeutic areas. By leveraging its capabilities, Nimble Therapeutics aims to enhance the empirical optimization of molecules, ultimately enabling medical professionals to develop next-generation peptide therapeutics with improved drug-like properties. The company's approach seeks to transform the landscape of peptide drug discovery and development, providing valuable solutions for the pharmaceutical industry.

Invisalert Solutions

Venture Round in 2019
Invisalert Solutions, Inc. specializes in developing compliance-based patient safety solutions for the healthcare sector. The company is known for its ObservSMART system, which includes a wristband and software that tracks 15-minute observation checks to enhance compliance and reduce the risk of missed or falsified information. This system provides proactive notifications for supervisory staff, facilitates communication among team members, and offers access to reports and analytics, thereby replacing traditional paper-based methods. Invisalert Solutions aims to improve patient care and safety, particularly in psychiatric and emergency room environments, and also addresses non-compliance issues in various sectors, including acute healthcare, corrections, drug delivery, long-term care, and special education. Founded in 2011, the company is headquartered in Newtown Square, Pennsylvania.

Teknova

Acquisition in 2019
Teknova specializes in providing essential reagents for bioprocessing, bioproduction, and molecular diagnostics, catering to the research, clinical, and applied markets. The company offers a range of products including pre-poured media plates, liquid cell culture media and supplements, protein and nucleic acid purification buffers, and molecular biology reagents. Teknova focuses on agility and customer satisfaction, ensuring it can meet complex formulation and packaging needs while delivering custom GMP products with quick turnaround times. Serving as a partner to the biopharmaceutical sector, Teknova's research and development team supports clients throughout the entire cell and gene therapy production workflow, from prototype design to GMP manufacturing guidance. The company primarily generates its revenue from the United States market.

Akoya Biosciences

Venture Round in 2018
Akoya Biosciences is a spatial biology company offering the most comprehensive, end-to-end solutions for high-parameter tissue analysis from discovery through clinical and translational research, enabling the development of more precise therapies for immuno-oncology and other drug development applications. The company has two industry-leading platforms that empower investigators and researchers to gain a deeper understanding of complex diseases such as cancer, and autoimmune or neurological disorders. The CODEX system is the only benchtop platform that can efficiently quantify more than 40 biomarkers and is ideally suited for biomarker discovery. The Phenoptics platform is the only end-to-end multiplexed immunofluorescence solution with the robustness and high throughput necessary for translational research and clinical trials.

Precision NanoSystem

Series B in 2018
Precision Nanosystems specializes in the development of tools and processes for the creation and manufacturing of nanoparticles used in medicine and medical research. The company offers a range of products, including the NanoAssemblr benchtop instrument, which facilitates the prototyping of nanoparticles and the development of nanoparticle-based drugs that deliver RNA, small molecules, and protein therapeutics. Additionally, Precision Nanosystems provides various kits, such as Neuro9Kit for studying gene function in neurons and glial cells, Test9Kit for gene function studies in diverse cell types, and Hepato9Kit for liver gene function analysis. Their microfluidic devices enable the rapid and cost-effective manufacturing of lipid nanoparticles that can encapsulate and deliver bioactive agents, supporting life sciences researchers in developing innovative treatments and therapies for various diseases.

Carterra

Venture Round in 2018
Carterra, Inc. specializes in developing and commercializing innovative biomolecular interaction analysis solutions, primarily utilizing label-free technologies. The company offers a range of products, including its MultipleX 96 array-based surface plasmon resonance (SPR) imaging system and the Continuous Flow Microspotter (CFM), which is designed for high-throughput microarray printing. Carterra's services encompass epitope binning and mapping, first-pass kinetics, and assay development, catering to the needs of pharmaceutical and biotechnology clients. Its advanced platforms enable users to conduct kinetic and epitope analysis, supporting the rapid screening of antibodies and identification of potential therapeutic candidates. Founded in 2005 and headquartered in Salt Lake City, Utah, Carterra has additional offices in California, Massachusetts, and Germany, and distributes its products globally, including in China and Japan.

Aquaro Histology

Series A in 2017
Aquaro Histology, Inc. specializes in manufacturing a section mounting system designed to enhance the histology workflow in laboratories. Founded in 2017 and based in Ann Arbor, Michigan, the company offers the Aquaro ASM, which automates the placement of paraffin-embedded tissue sections onto slides. This compact and user-friendly unit is compatible with existing microtomes, aiming to improve workflow efficiency, section quality, and consistency in histology laboratories. By streamlining the mounting process, Aquaro Histology's product supports enhanced patient diagnosis and care.

RareCyte

Venture Round in 2017
RareCyte, Inc. is a life sciences company based in Seattle, Washington, specializing in the development of innovative platforms for the analysis of liquid and tissue biopsies. Founded in 2009, the company focuses on the detection and characterization of rare cells, particularly circulating tumor cells (CTCs) and circulating endothelial cells (CECs), which are critical for advancing precision medicine in oncology and cardiovascular disease. RareCyte's AccuCyte system offers an open platform that allows for the unbiased discovery and isolation of these rare cells from whole blood. The company provides a comprehensive suite of products, including sample preparation systems, staining kits, automated microscopy instruments, and imaging systems, which are utilized in various applications such as liquid biopsies, single-cell retrieval, and multi-parameter tissue analysis. By equipping researchers and medical professionals with advanced tools, RareCyte aims to enhance clinical research and foster the development of targeted therapies.

Akoya Biosciences

Venture Round in 2017
Akoya Biosciences is a spatial biology company offering the most comprehensive, end-to-end solutions for high-parameter tissue analysis from discovery through clinical and translational research, enabling the development of more precise therapies for immuno-oncology and other drug development applications. The company has two industry-leading platforms that empower investigators and researchers to gain a deeper understanding of complex diseases such as cancer, and autoimmune or neurological disorders. The CODEX system is the only benchtop platform that can efficiently quantify more than 40 biomarkers and is ideally suited for biomarker discovery. The Phenoptics platform is the only end-to-end multiplexed immunofluorescence solution with the robustness and high throughput necessary for translational research and clinical trials.

Dynex Technologies

Acquisition in 2017
Dynex Technologies, Inc. specializes in the design, engineering, manufacturing, and distribution of fully-automated ELISA microplate workstations, laboratory instruments, and their associated consumables and accessories. The company's products integrate advanced detection technology with automated sample handling, allowing scientists and clinicians to enhance their research capabilities and improve diagnostic accuracy. Dynex Technologies serves a global market through distributors in the Americas, Asia, Europe, the Middle East, and Africa, as well as through online channels. Founded in 1952 and based in Chantilly, Virginia, the company was previously known as Dynatech Laboratories, Inc. until it rebranded in 1996. In addition to its product offerings, Dynex provides technical support services to ensure customer satisfaction and operational efficiency.

Medpricer

Venture Round in 2017
Medpricer develops a purchased services cost management solution tailored for the healthcare industry. The company's flagship platform, mSource, enables healthcare providers to discover, organize, benchmark, and manage their spending on service providers effectively. By offering precision benchmark reports, project management, and advisory services, Medpricer helps healthcare organizations enhance visibility and control over their expenses. This approach can lead to significant improvements in operating margins, with potential savings of up to 5%. Founded in 2004 and headquartered in Guilford, Connecticut, Medpricer also has an office in Walnut Creek, California. As of October 2019, it operates as a subsidiary of Premier, Inc.

TrakCel

Venture Round in 2016
TrakCel Ltd. is a technology company that provides a comprehensive suite of integrated solutions for managing the cell therapy supply chain, catering to both autologous and allogeneic therapies. Founded in 2012 and headquartered in Cardiff, United Kingdom, TrakCel offers a cloud-based Cell Orchestration Platform that enhances the efficiency of cell and gene therapy development. This platform enables users to collate, track, and document critical information throughout various stages of therapy programs, facilitating compliance with regulatory audits. The company serves a diverse clientele, including medical centers, logistics providers, manufacturers, and therapy developers, and collaborates with both commercial and academic organizations focused on improving human health. By replacing outdated paper-based systems, TrakCel's technology helps streamline data management, reporting, and analysis needs in clinical trials, ultimately reducing time, costs, and risks associated with therapy development.

Precision NanoSystem

Series A in 2015
Precision Nanosystems specializes in the development of tools and processes for the creation and manufacturing of nanoparticles used in medicine and medical research. The company offers a range of products, including the NanoAssemblr benchtop instrument, which facilitates the prototyping of nanoparticles and the development of nanoparticle-based drugs that deliver RNA, small molecules, and protein therapeutics. Additionally, Precision Nanosystems provides various kits, such as Neuro9Kit for studying gene function in neurons and glial cells, Test9Kit for gene function studies in diverse cell types, and Hepato9Kit for liver gene function analysis. Their microfluidic devices enable the rapid and cost-effective manufacturing of lipid nanoparticles that can encapsulate and deliver bioactive agents, supporting life sciences researchers in developing innovative treatments and therapies for various diseases.

RareCyte

Venture Round in 2012
RareCyte, Inc. is a life sciences company based in Seattle, Washington, specializing in the development of innovative platforms for the analysis of liquid and tissue biopsies. Founded in 2009, the company focuses on the detection and characterization of rare cells, particularly circulating tumor cells (CTCs) and circulating endothelial cells (CECs), which are critical for advancing precision medicine in oncology and cardiovascular disease. RareCyte's AccuCyte system offers an open platform that allows for the unbiased discovery and isolation of these rare cells from whole blood. The company provides a comprehensive suite of products, including sample preparation systems, staining kits, automated microscopy instruments, and imaging systems, which are utilized in various applications such as liquid biopsies, single-cell retrieval, and multi-parameter tissue analysis. By equipping researchers and medical professionals with advanced tools, RareCyte aims to enhance clinical research and foster the development of targeted therapies.

PneumRx

Venture Round in 2011
PneumRx, Inc. is a medical device company founded in 2004 and based in Mountain View, California. The company specializes in developing minimally invasive treatments specifically for patients suffering from emphysema. Its primary product is the RePneu Lung Volume Reduction Coil, an investigational device designed to improve lung function and quality of life for individuals affected by this chronic respiratory condition.

Estech

Series D in 2010
Estech is a privately held medical device manufacturing and distribution company based in San Ramon, California. Founded in 1996 by Arthur and Raymond Bertolero, the company focuses on developing and marketing medical devices and disposables that facilitate both traditional and minimally invasive cardiac surgical procedures. Estech has established a global distribution network and is recognized for attracting skilled professionals in the medical device sector. The company's commitment to innovation and quality has enabled it to achieve sustained success in a competitive industry, reflecting the dedication of its team across all departments.

AltheaDx

Series A in 2010
AltheaDx, Inc. is a molecular diagnostics company based in San Diego, California, specializing in pharmacogenetics. The company employs an algorithm-based bioinformatics platform alongside a portfolio of pharmacogenomic product tests to aid healthcare providers in determining the most effective medications and appropriate dosing for patients based on their genetic profiles and existing treatment plans. Its IDgenetix test facilitates personalized treatment strategies for common health issues such as cardiovascular diseases, neuropsychiatric disorders, and pain management. Additionally, AltheaDx provides comprehensive research and development services, focusing on molecular biomarker discovery, assay development, and clinical trial support for pharmaceutical and biotech companies. The company serves a diverse clientele, including long-term care facilities, managed care organizations, and individual healthcare providers, thereby contributing to improved patient outcomes through tailored therapeutic decisions.

BioVentrix

Debt Financing in 2009
BioVentrix, Inc. is a medical device company based in San Ramon, California, that specializes in innovative treatments for congestive heart failure (CHF), particularly in patients with ischemic cardiomyopathy. Founded in 2003, the company has developed the Revivent Myocardial Anchoring System, which utilizes a hybrid closed-chest transcatheter procedure to enhance cardiac function. This device operates by restoring the size and volume of the left ventricle through the implantation of micro-anchoring pairs that effectively exclude scarred myocardium from healthy tissue. BioVentrix aims to provide less invasive, catheter-based solutions to improve patient outcomes and slow the progression of CHF, addressing a critical need in cardiac care.

Estech

Venture Round in 2009
Estech is a privately held medical device manufacturing and distribution company based in San Ramon, California. Founded in 1996 by Arthur and Raymond Bertolero, the company focuses on developing and marketing medical devices and disposables that facilitate both traditional and minimally invasive cardiac surgical procedures. Estech has established a global distribution network and is recognized for attracting skilled professionals in the medical device sector. The company's commitment to innovation and quality has enabled it to achieve sustained success in a competitive industry, reflecting the dedication of its team across all departments.

Estech

Venture Round in 2008
Estech is a privately held medical device manufacturing and distribution company based in San Ramon, California. Founded in 1996 by Arthur and Raymond Bertolero, the company focuses on developing and marketing medical devices and disposables that facilitate both traditional and minimally invasive cardiac surgical procedures. Estech has established a global distribution network and is recognized for attracting skilled professionals in the medical device sector. The company's commitment to innovation and quality has enabled it to achieve sustained success in a competitive industry, reflecting the dedication of its team across all departments.

Freedom Innovations LLC.

Funding Round in 2008
Freedom Innovations LLC specializes in the design and manufacture of prosthetic devices, focusing on lower limb solutions tailored for users with varying mobility levels, from low to high. The company offers a diverse range of prosthetic feet suitable for everyday walking and extreme sports, ensuring users can engage in a wide array of activities. Freedom Innovations collaborates closely with prosthetists and amputees to develop products that enhance the quality of life for individuals with disabilities, enabling them to lead more active and fulfilling lives.

Confirma

Series C in 2008
Confirma is the only company that develops and markets an MRI-CAD system, CADstream, revolutionizing MRI study analysis and reporting through automated and standardized processing. CADstream automates the analysis and interventional guidance of MRI studies, providing higher quality imaging studies, lower costs for radiology practices and improved communication tools for physicians and patients. CADstream can be integrated into any workflow scenario and is compatible with all MRI scanners and PACS.

Asuragen

Series B in 2007
Asuragen, Inc. is a molecular diagnostics company based in Austin, Texas, focused on providing patient management solutions for oncology and genetic disorders. Founded in 2005, Asuragen develops and commercializes diagnostic products for clinical laboratories and biopharma partners. Its product portfolio includes the AmplideX FMR1 PCR reagents for detecting CGG repeats in the fragile X mental retardation gene, various cancer testing kits like QUANTIDEX, and the Signature technology for multiplex analysis of nucleic acid sequences, which includes assays for mutations in KRAS and BRAF genes. In addition to these diagnostic tools, Asuragen offers GLP testing services, cGMP manufacturing capabilities, and expertise in biomarker discovery and regulatory processes. This integrated approach facilitates the development, testing, and commercialization of diagnostic solutions aimed at improving treatment outcomes in oncology and genetic conditions.

AngioScore

Series E in 2007
AngioScore Inc. is engaged in the development, manufacturing, and marketing of medical devices, specifically focusing on the AngioSculpt Scoring Balloon Catheter. This catheter is designed for use in both coronary and peripheral interventional markets, addressing the limitations commonly associated with traditional angioplasty balloon catheters. The AngioSculpt features a semi-compliant balloon combined with a unique nitinol scoring element, enhancing its effectiveness in endovascular therapy. The company's products are aimed at improving the treatment of cardiovascular and vascular diseases.

LDR Holding

Series C in 2007
LDR Holding Corporation is a medical device company that specializes in developing and marketing implantable spine systems and instrumentation for both patients and surgeons. The company offers a range of spinal surgery solutions, including artificial disc systems, pedicle screw systems, cervical cages, and various implant systems designed for cervical and lumbar applications. LDR Holding also provides synthetic bone substitutes and innovative surgical technologies, such as the VerteBRIDGE product, which is tailored for specific surgical procedures. Its products are distributed in numerous countries, including Australia, Japan, and various European nations, through partnerships with surgeons and distributors. Founded in 2004 and headquartered in Austin, Texas, LDR Holding has expanded its presence internationally with additional offices in France, China, Brazil, and Germany. The company was previously known as LDR Spine USA, Inc. before rebranding following its acquisition of LDR Médical.

PneumRx

Series B in 2007
PneumRx, Inc. is a medical device company founded in 2004 and based in Mountain View, California. The company specializes in developing minimally invasive treatments specifically for patients suffering from emphysema. Its primary product is the RePneu Lung Volume Reduction Coil, an investigational device designed to improve lung function and quality of life for individuals affected by this chronic respiratory condition.

Althea Technologies

Series C in 2007
Althea Technologies specializes in contract manufacturing services for the pharmaceutical and biotechnology sectors. The company provides gene expression analysis through its eXpress Profiling technology and quantitative PCR testing services. Additionally, Althea Technologies offers cGMP drug product filling in vials and syringes, as well as the production of microbial-derived recombinant proteins and plasmid DNA. With its focus on high-quality manufacturing and innovative analytical services, Althea Technologies serves a critical role in the development and supply of biopharmaceutical products.

Asuragen

Series A in 2006
Asuragen, Inc. is a molecular diagnostics company based in Austin, Texas, focused on providing patient management solutions for oncology and genetic disorders. Founded in 2005, Asuragen develops and commercializes diagnostic products for clinical laboratories and biopharma partners. Its product portfolio includes the AmplideX FMR1 PCR reagents for detecting CGG repeats in the fragile X mental retardation gene, various cancer testing kits like QUANTIDEX, and the Signature technology for multiplex analysis of nucleic acid sequences, which includes assays for mutations in KRAS and BRAF genes. In addition to these diagnostic tools, Asuragen offers GLP testing services, cGMP manufacturing capabilities, and expertise in biomarker discovery and regulatory processes. This integrated approach facilitates the development, testing, and commercialization of diagnostic solutions aimed at improving treatment outcomes in oncology and genetic conditions.

AngioScore

Series D in 2006
AngioScore Inc. is engaged in the development, manufacturing, and marketing of medical devices, specifically focusing on the AngioSculpt Scoring Balloon Catheter. This catheter is designed for use in both coronary and peripheral interventional markets, addressing the limitations commonly associated with traditional angioplasty balloon catheters. The AngioSculpt features a semi-compliant balloon combined with a unique nitinol scoring element, enhancing its effectiveness in endovascular therapy. The company's products are aimed at improving the treatment of cardiovascular and vascular diseases.

Accumetrics

Series B in 2004
Accumetrics is a privately-held company based in San Diego, California, that specializes in the development, manufacturing, and marketing of the VerifyNow System, which includes a comprehensive suite of assays for assessing platelet function. Founded in 1996, the company initially sold to Radiometer in 2000 but was repurchased by its management and investors in 2003. Accumetrics focuses on diagnostic instrumentation and test kits designed to measure individual responses to various antiplatelet agents, providing essential tools for healthcare professionals in the evaluation of platelet activity and ensuring effective patient treatment.

Estech

Series B in 2003
Estech is a privately held medical device manufacturing and distribution company based in San Ramon, California. Founded in 1996 by Arthur and Raymond Bertolero, the company focuses on developing and marketing medical devices and disposables that facilitate both traditional and minimally invasive cardiac surgical procedures. Estech has established a global distribution network and is recognized for attracting skilled professionals in the medical device sector. The company's commitment to innovation and quality has enabled it to achieve sustained success in a competitive industry, reflecting the dedication of its team across all departments.
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