Trevi Health Ventures

US HealthVest is a behavioral healthcare firm that focuses on transforming the psychiatric hospital sector. The company's business model centers on developing new facilities as well as acquiring existing ones that have untapped potential. Each facility is designed to provide a range of services tailored to meet the diverse needs of various patient populations. The leadership team at US HealthVest has a proven track record in the psychiatric hospital industry, having previously established and sold successful businesses, including Ascend Health, which operated nine freestanding facilities and nearly 900 beds before its acquisition by Universal Health Services in 2012. The firm's predecessor, Heartland Health Developments, also specialized in psychiatric care and was sold to Psychiatric Solutions in 2004.

Manhattan Labs, established in 2008, aims to be a leading independent clinical laboratory in the New York City metropolitan area. The organization focuses on delivering high-quality, service-oriented medical diagnostic testing while utilizing advanced laboratory technology. Known for personalized service, Manhattan Labs emphasizes exceptional turnaround times and easy access to results, positioning itself as a benchmark for quality and service in the laboratory industry.

Paradigm Spine, LLC is a privately-held medical device company specializing in the design and development of innovative solutions for spinal diseases. Headquartered in New York, the company focuses on non-fusion spinal implants and motion-preserving products aimed at treating various spinal disorders. Its notable offerings include the Coflex interspinous implant, which is used for managing facet arthrosis and decompressive procedures, and a minimally invasive pedicle-screw based system known as the DSS system. These products are designed to stabilize the spine while preserving natural anatomical function, catering to the needs of spine specialists globally. Established in 2002 and originally named Spine Motion, LLC, the company rebranded to Paradigm Spine in 2005.

Small Bone Innovations (SBi) is a medical device company specializing in the design, manufacture, and distribution of implants tailored for small bones and joints. Their product portfolio focuses on trauma and arthroplasty applications, catering specifically to the thumb, hand, wrist, elbow, foot, and ankle regions. SBi's offerings include basal joint arthritis treatments and implants designed to replace anatomic joint surfaces while preserving bones and minimizing disruption to collateral ligaments and soft tissues.

MedAvante, Inc. is a company that specializes in technology-enabled signal detection solutions for clinical trials focused on central nervous system disorders. Founded in 2002 and based in Hamilton, New Jersey, MedAvante offers a range of services including the Virgil Investigative Study Platform for site-based assessments and MedAvante Central Ratings for live assessments conducted by remote clinicians. The company also provides scientific risk reduction services such as rater qualification and training, central review, and remote ratings, which help maintain the integrity of trial data by minimizing bias and variability. MedAvante has established a standardized group of expert Central raters who conduct live interviews with trial subjects via videoconferencing or telephone, contributing to successful outcomes in numerous global trials. Since May 2017, MedAvante operates as a subsidiary of WIRB - Copernicus Group, Inc.

Small Bone Innovations (SBi) is a medical device company specializing in the design, manufacture, and distribution of implants tailored for small bones and joints. Their product portfolio focuses on trauma and arthroplasty applications, catering specifically to the thumb, hand, wrist, elbow, foot, and ankle regions. SBi's offerings include basal joint arthritis treatments and implants designed to replace anatomic joint surfaces while preserving bones and minimizing disruption to collateral ligaments and soft tissues.

Optovue, Inc. is an ophthalmic device company based in Fremont, California, specializing in the design, development, and manufacturing of advanced imaging technologies for eye care professionals and clinical researchers. Founded in 2003, Optovue focuses on spectral-domain optical coherence tomography (OCT) and angiography solutions that enhance the diagnosis and management of ocular diseases. The company's product offerings include AngioVue for vascular visualization in the retina, Avanti for assessing peripheral retina pathology, and iFusion, which combines OCT with fundus imaging. Additional products such as iVue, NetVue Pro, and iWellness provide comprehensive scanning, networking, and early diagnosis support. Optovue’s innovative technology, characterized by ultra-high speed and resolution, supports the detection and treatment of conditions such as macular degeneration and diabetic retinopathy, ultimately improving patient outcomes and advancing the field of ophthalmology.

Omeros discovers, develops, and commercializes small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system, immunologic disorders, cancers, and addictive/compulsive disorders.

Ikonisys, Inc. is a medical diagnostic company focused on the design, manufacture, and marketing of advanced diagnostic products for cancer detection and genetic disorder screening. Headquartered in New Haven, Connecticut, Ikonisys offers a range of innovative tools, including the Ikoniscope Robotic Microscope, which automates slide handling and image analysis, reducing human error in testing. Their product line features various oncoFISH applications, such as those for bladder cancer and HER2 status in breast tissue, as well as tools for detecting genetic abnormalities in prostate tissue biopsies. The company is committed to transforming diagnostic medicine by enabling early and accurate disease detection through a combination of cutting-edge technology and scientific research, ultimately assisting healthcare professionals in providing optimal patient care. Founded in 1999, Ikonisys continues to advance its capabilities in non-invasive diagnostic solutions.