Two Bear Capital

Montara Therapeutics is a biotechnology company that focuses on developing a precision pharmacology platform aimed at creating innovative therapies for central nervous system diseases. By leveraging human genetics and machine learning, the company identifies and validates drug targets, which enhances the ability of medical professionals to deliver safe and effective treatments for patients suffering from neurological disorders. Montara Therapeutics' approach is designed to improve therapeutic outcomes and address unmet medical needs in the field of neurology.

QuSecure, Inc. is a cybersecurity company based in Menlo Park, California, founded in 2019. It specializes in post-quantum cybersecurity solutions, leveraging advancements in quantum computing to enhance data security infrastructure. QuSecure's flagship offering, the QuProtect software platform, delivers a comprehensive quantum-security-as-a-service framework designed to provide zero-trust, quantum-resilient technology that safeguards networks, cloud systems, edge devices, and end users from both current cyber threats and future quantum risks. The company also develops a range of security products, including automated cryptographic testing and multi-layer security technologies, which encompass a security management server, quantum-resistant blockchain solutions, and biometric identity systems. In addition to its product offerings, QuSecure provides consulting services focused on governance, compliance, security strategy, and computing education, enabling enterprises to strengthen their cybersecurity posture without significant disruptions to existing systems.

Selector AI is a technology company that offers an operational intelligence platform designed for managing multi-domain network and application infrastructures across diverse cloud environments. The platform ingests data from various sources, employs automated anomaly detection using AI/ML algorithms, and delivers actionable insights to help clients meet their service key performance indicators (KPIs). It facilitates seamless collaboration among operators via messaging platforms, offers search-driven querying with a conversational user experience, and automates data engineering pipelines.

Talus Bio is a biotechnology startup focused on drug discovery and development, particularly targeting challenging cancer transcription factors. The company employs an innovative approach that integrates functional proteomics, automated biology, and machine learning. Their MARMOT platform utilizes AI, advanced proteomics, synthetic chemistry, and computational biology to design and analyze drugs, proteins, and genomics. This platform is designed to advance drug development for gene regulation in oncology, aiming to create small-molecule therapies that can effectively control gene expression in cancer cells.

Montara Therapeutics is a biotechnology company that focuses on developing a precision pharmacology platform aimed at creating innovative therapies for central nervous system diseases. By leveraging human genetics and machine learning, the company identifies and validates drug targets, which enhances the ability of medical professionals to deliver safe and effective treatments for patients suffering from neurological disorders. Montara Therapeutics' approach is designed to improve therapeutic outcomes and address unmet medical needs in the field of neurology.

Elisity is a company dedicated to securing access to enterprise assets and data in an increasingly complex digital landscape characterized by mobile workforces and blurred organizational boundaries. It offers a cloud-based platform focused on least privilege access and identity-based micro-segmentation. This platform utilizes artificial intelligence to continuously verify user identity, location, permissions, and device behavior, thereby granting users, applications, data, and devices only the access necessary for their roles. By enabling organizations to enforce granular access control policies, Elisity helps them achieve a zero-trust security model. The company is comprised of skilled entrepreneurs with extensive technical expertise in enterprise networking and security, serving some of the world's largest and most security-conscious organizations.

Binarly is a global company focused on firmware and software supply chain security, established in 2021 and headquartered in Los Angeles, California. The company offers the Binarly Transparency Platform, an AI-powered solution designed for device manufacturers, original equipment manufacturers, independent software vendors, and product security teams. This platform enables users to identify both known and unknown vulnerabilities, misconfigurations, and potential signs of malicious code within their firmware. By employing advanced machine learning and code analysis techniques, Binarly's platform provides in-depth introspection of firmware to detect threats that may arise below the operating system. The company’s validated remediation playbooks assist clients in significantly reducing the cost and time associated with addressing security exposures, ultimately aiming to protect businesses, critical infrastructure, and consumers globally.

Dymium is addressing one of the most pressing issues organizations are faced with today: how to securely and cost-effectively manage the data access requirements across a proliferation of data in the midst of an advancing world of cloud technology, data analytics, distributed development environments and AI-projects. Dymium takes data protection to where your data lives rather than you having to move it, make copies of it or build yet another data lake or warehouse. The Dymium Platform uniquely combines a zero-trust architecture, real-time data transformation services and universal access policies across your existing data infrastructure wherever that data may live so that it is more secure, efficient and cost-effective to innovate. We believe that you don’t need to move your data or make more copies of your data in order for you to use it for innovation. This only opens up your organization to greater risk and unnecessary cost.

TileDB, Inc. is a technology company specializing in the management of multi-dimensional array data, primarily for scientific applications. Founded in 2017 and headquartered in Cambridge, Massachusetts, with an additional location in Athens, Greece, TileDB offers a cloud-based storage platform and embedded storage engine. Its innovative software is designed to handle diverse data types, including unstructured and multimodal data, making it suitable for complex scientific inquiries such as genomic research and biomedical imaging. TileDB enables users to access, analyze, and share intricate datasets effectively, supporting scientific teams in pharmaceutical and biotechnology sectors to advance drug discovery and other research initiatives. Through its robust platform, TileDB facilitates parallel data analytics and integrates various dimensions and attributes within data arrays, positioning itself as a critical tool for scientific breakthroughs.

Graphiant Inc. is a networking technology company founded in 2020 and headquartered in San Jose, California. It specializes in developing innovative solutions for wide area networks (WAN), particularly through its Graphiant Network Edge, a software-as-a-service platform. This technology facilitates connectivity across enterprise WANs, hybrid cloud environments, and network edges, enhancing the ability of businesses to connect with clients and partners efficiently. By integrating high-performance capabilities similar to multiprotocol label switching with the agility of internet-based systems, Graphiant's offerings empower network architects to create robust, enterprise-grade networks that keep pace with business demands.

Abilita Bio is a biotechnology company that focuses on enabling the discovery and development of drugs targeting membrane proteins, including G Protein Coupled Receptors (GPCRs) and ion channels.

Novoron Bioscience, Inc. is a biotechnology company based in San Diego, California, focused on the research and development of innovative treatments for various central nervous system (CNS) disorders. Founded in 2013, the company specializes in creating therapeutic approaches that target neurological damage and diseases such as Alzheimer's, multiple sclerosis, spinal cord injuries, and glaucoma. Novoron’s proprietary science concentrates on lipoprotein-receptor drugs that aim to repair brain and spinal cord degeneration at both whole-receptor and micro-domain levels. The company's pipeline includes pre-clinical therapies designed to address acute conditions and demyelinating diseases, offering potential hope for patients with conditions that currently lack effective treatments.

Arch Systems Inc. specializes in designing and developing a modular hardware platform that connects devices to the cloud for industrial Internet of Things (IoT) applications. Founded in 2015 and based in Mountain View, California, the company provides a comprehensive industry-4.0 machine data and AI platform tailored for electronics and discrete manufacturers. Arch Systems focuses on digitizing both new and existing factories, significantly enhancing machine utilization through its Arch Utilization Suite, which enables improvements of 20–40%. The platform collects real-time and predictive analytics from all machines, both new and legacy, across enterprise supply chains, facilitating better insights and data accessibility. Additionally, Arch Systems boasts one of the largest surface mount technology (SMT) machine connector libraries globally and collaborates with leading PCB manufacturing machine vendors, thereby supporting a wide range of custom IoT applications across various sectors, including food, water, and energy.

CIQ is an IT company specializing in enterprise software solutions that facilitate secure hybrid orchestration for performance-intensive workflows. It offers a range of software infrastructure tools, security solutions, and workflow automation designed to support industries such as pharmaceuticals, government, military, high-performance computing, and research. By integrating the essential capabilities of enterprise systems, hyper-scale environments, and high-performance computing, CIQ enables intelligent, secure, and efficient orchestration of workflows and data across multiple clouds and sites. This approach accelerates the speed and efficiency of complex operations, helping organizations enhance their performance and operational effectiveness.

Selector AI is a technology company that offers an operational intelligence platform designed for managing multi-domain network and application infrastructures across diverse cloud environments. The platform ingests data from various sources, employs automated anomaly detection using AI/ML algorithms, and delivers actionable insights to help clients meet their service key performance indicators (KPIs). It facilitates seamless collaboration among operators via messaging platforms, offers search-driven querying with a conversational user experience, and automates data engineering pipelines.

Novoron Bioscience, Inc. is a biotechnology company based in San Diego, California, focused on the research and development of innovative treatments for various central nervous system (CNS) disorders. Founded in 2013, the company specializes in creating therapeutic approaches that target neurological damage and diseases such as Alzheimer's, multiple sclerosis, spinal cord injuries, and glaucoma. Novoron’s proprietary science concentrates on lipoprotein-receptor drugs that aim to repair brain and spinal cord degeneration at both whole-receptor and micro-domain levels. The company's pipeline includes pre-clinical therapies designed to address acute conditions and demyelinating diseases, offering potential hope for patients with conditions that currently lack effective treatments.

Novoron Bioscience, Inc. is a biotechnology company based in San Diego, California, focused on the research and development of innovative treatments for various central nervous system (CNS) disorders. Founded in 2013, the company specializes in creating therapeutic approaches that target neurological damage and diseases such as Alzheimer's, multiple sclerosis, spinal cord injuries, and glaucoma. Novoron’s proprietary science concentrates on lipoprotein-receptor drugs that aim to repair brain and spinal cord degeneration at both whole-receptor and micro-domain levels. The company's pipeline includes pre-clinical therapies designed to address acute conditions and demyelinating diseases, offering potential hope for patients with conditions that currently lack effective treatments.

Elisity is a company dedicated to securing access to enterprise assets and data in an increasingly complex digital landscape characterized by mobile workforces and blurred organizational boundaries. It offers a cloud-based platform focused on least privilege access and identity-based micro-segmentation. This platform utilizes artificial intelligence to continuously verify user identity, location, permissions, and device behavior, thereby granting users, applications, data, and devices only the access necessary for their roles. By enabling organizations to enforce granular access control policies, Elisity helps them achieve a zero-trust security model. The company is comprised of skilled entrepreneurs with extensive technical expertise in enterprise networking and security, serving some of the world's largest and most security-conscious organizations.

PulseData AI, established in 2015 and headquartered in New York, specializes in healthcare technology. It develops machine learning software that helps healthcare providers identify patients at high risk of adverse, preventable medical outcomes. The company's platform analyzes vast amounts of patient data to predict health trends, enabling care management teams to deliver timely, targeted care, and ultimately reduce preventable illnesses and medical costs.

Graphiant Inc. is a networking technology company founded in 2020 and headquartered in San Jose, California. It specializes in developing innovative solutions for wide area networks (WAN), particularly through its Graphiant Network Edge, a software-as-a-service platform. This technology facilitates connectivity across enterprise WANs, hybrid cloud environments, and network edges, enhancing the ability of businesses to connect with clients and partners efficiently. By integrating high-performance capabilities similar to multiprotocol label switching with the agility of internet-based systems, Graphiant's offerings empower network architects to create robust, enterprise-grade networks that keep pace with business demands.

TileDB, Inc. is a technology company specializing in the management of multi-dimensional array data, primarily for scientific applications. Founded in 2017 and headquartered in Cambridge, Massachusetts, with an additional location in Athens, Greece, TileDB offers a cloud-based storage platform and embedded storage engine. Its innovative software is designed to handle diverse data types, including unstructured and multimodal data, making it suitable for complex scientific inquiries such as genomic research and biomedical imaging. TileDB enables users to access, analyze, and share intricate datasets effectively, supporting scientific teams in pharmaceutical and biotechnology sectors to advance drug discovery and other research initiatives. Through its robust platform, TileDB facilitates parallel data analytics and integrates various dimensions and attributes within data arrays, positioning itself as a critical tool for scientific breakthroughs.

Inimmune Corp. is a biotechnology company based in Missoula, Montana, founded in 2016. The company specializes in the discovery and development of innovative vaccines and immunotherapeutics aimed at treating and preventing a variety of conditions, including oncology, allergic rhinitis, food allergies, infectious diseases, and respiratory infections. Inimmune focuses on the optimization of innate immune receptor agonists and antagonists, which are designed to address a wide range of medical issues such as allergy, autoimmune diseases, and cancer. Through its research, Inimmune endeavors to enhance therapeutic options for patients suffering from these diverse health challenges.

VERAFĪ operates as a SaaS-based platform focused on private intelligence and due diligence, aiming to enhance fraud prevention in various sectors. The company integrates human expertise from the intelligence community with advanced machine learning technology, catering to professionals in private equity, venture capital, and commercial credit. This approach allows users to access critical intelligence efficiently, facilitating a smoother deal flow process. By addressing the needs of the corporate and human diligence markets, VERAFĪ provides tools for effective KYC (Know Your Customer), enhanced due diligence, pre-employment screening, and fraud detection, thus promoting a more secure business environment.

VERAFĪ operates as a SaaS-based platform focused on private intelligence and due diligence, aiming to enhance fraud prevention in various sectors. The company integrates human expertise from the intelligence community with advanced machine learning technology, catering to professionals in private equity, venture capital, and commercial credit. This approach allows users to access critical intelligence efficiently, facilitating a smoother deal flow process. By addressing the needs of the corporate and human diligence markets, VERAFĪ provides tools for effective KYC (Know Your Customer), enhanced due diligence, pre-employment screening, and fraud detection, thus promoting a more secure business environment.

Graphiant Inc. is a networking technology company founded in 2020 and headquartered in San Jose, California. It specializes in developing innovative solutions for wide area networks (WAN), particularly through its Graphiant Network Edge, a software-as-a-service platform. This technology facilitates connectivity across enterprise WANs, hybrid cloud environments, and network edges, enhancing the ability of businesses to connect with clients and partners efficiently. By integrating high-performance capabilities similar to multiprotocol label switching with the agility of internet-based systems, Graphiant's offerings empower network architects to create robust, enterprise-grade networks that keep pace with business demands.