Boundless Bio, Inc., biopharma company, develops therapies and medicines for the treatment of cancers. It offers therapeutics based on extrachromosomal DNA (ecDNA) one of the drivers of the aggressive cancers, such as cancers characterized by high copy number amplification of oncogenes. The company was formerly known as Pretzel Therapeutics, Inc. Boundless Bio, Inc. was founded in 2018 and is based in LA Jolla, California.
Quince is a new e-commerce company that focuses on leveraging an M2C supply chain to deliver premium essentials at the lowest market price. It acts as a thin storefront to bring manufacturers and artisans closer to their customers through shared partnership in brand or marketing. The company was founded in 2018 and is headquartered in San Francisco, California.
AMP Robotics Corporation specializes in designing and manufacturing robotic systems for material recovery facilities and recycling operations, focusing on automating the identification, sorting, and processing of complex waste streams. The company's flagship product, AMP Cortex, utilizes advanced robotics and computer vision technology to efficiently pick and sort recyclable materials, significantly lowering sorting costs. Additionally, AMP Neuron, a software solution, captures and analyzes material data to identify features in a manner similar to human perception. By leveraging artificial intelligence and machine learning, AMP Robotics enhances recycling processes for various waste types, including municipal solid waste and e-waste. The modular design of its systems allows for easy integration into existing infrastructure, minimizing disruption and capital investment. Founded in 2014 and headquartered in Louisville, Colorado, AMP Robotics has formed strategic partnerships to further its mission of improving recycling rates and economic recovery of recyclables.
Saluda Medical Pty Ltd. is a medical device company focused on developing innovative solutions for the neuromodulation industry. The firm is known for its investigational device, Evoke, which features a closed-loop spinal cord stimulation system. This technology measures the spinal cord's response to stimulation and adjusts the stimulation parameters in real-time to optimize therapeutic outcomes for patients. Founded in 2010 and headquartered in Artarmon, Australia, with additional offices in Minnesota and the United Kingdom, Saluda Medical aims to provide effective treatment for chronic neuropathic pain. The company's unique approach involves monitoring each patient's neural fingerprint to automatically tailor electrical stimulation, ensuring that therapy is customized to meet individual needs. Saluda Medical's commitment to advancing medical technology is underpinned by a strong foundation of scientific research and a team of experienced professionals.
RayzeBio, Inc. is a biotechnology company based in San Diego, California, founded in 2020. The company specializes in developing tumor-targeted small molecule medicines that utilize radioisotopes, particularly focusing on alpha-emitting isotopes like Actinium-225 for the treatment of solid tumors. RayzeBio aims to improve cancer treatment outcomes by creating a robust pipeline of radiopharmaceuticals targeting validated oncology drug targets. Its portfolio includes multiple drug candidates at various stages of development, ranging from discovery to late-stage clinical programs, addressing significant market opportunities in the field of cancer therapeutics.
Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.
Moving Analytics. is a tele-health company dedicated to helping people thrive after heart disease. Our flagship product is Movn a virtual cardiac rehabilitation program that leverages evidence based guidelines, behavioral science, remote monitoring and personalized coaching to help patients recover to full health after a cardiac event. Movn is currently used by the Veterans Affairs Medical Center, Highmark Health Plan, Kaiser Permanente Northwest and many more health systems across the US.
FalconX, Ltd. is a digital asset trading platform based in San Francisco, California, that specializes in providing trading solutions using data science and blockchain technology. Founded in 2018, the company has rapidly established itself in the market, achieving $7 billion in global trading volume over a recent ten-month period, with a quarterly growth rate exceeding 600%. FalconX caters to a diverse clientele, including over 100 financial institutions such as hedge funds, proprietary trading firms, payment gateways, and cryptocurrency exchanges. The platform is designed to offer reliable execution for mid-to-large size trades, employing machine learning to optimize trade execution by smart routing orders across various liquidity sources. This approach helps clients minimize slippage and eliminate hidden fees, facilitating efficient currency exchange and transfer within the cryptocurrency markets.
Guild Education, Inc. is an educational technology company founded in 2015 and headquartered in Denver, Colorado. The company provides a lifelong learning platform designed for working adults, offering a range of online courses, workshops, and educational programs. These include bachelor’s and master’s degrees, high school diplomas, certificate programs, and language learning opportunities. Guild Education supports its users throughout their educational journey by utilizing a technology platform that facilitates discovery and learning, as well as a tech-enabled student advising model to enhance the overall experience. The company aims to empower adults to advance their education and career paths effectively.
Arcadia, Inc. is a clean energy technology company that provides a platform connecting subscribers to wind farms and community solar projects across the United States. Founded in 2014 and based in Washington, D.C., the company enables users to sign up for clean energy options available in their area and receive compensation when matched with a clean energy source. Arcadia's platform allows customers to manage their accounts, track energy usage, and access monthly billing, facilitating a seamless experience for households and businesses. By aggregating clean energy supply and integrating data across utilities, Arcadia aims to enhance user engagement and control over energy consumption while promoting sustainable energy solutions.
Span.IO, Inc. is a San Francisco-based company that specializes in developing renewable energy products for residential use. Founded in 2018, it offers innovative solutions including a smart electrical panel designed to replace traditional panels, serving as a central hub for home energy management. The accompanying application, known as The Span, allows homeowners to monitor and control their energy usage remotely, facilitating scheduling and alert notifications. Span.IO aims to simplify the adoption of renewable energy and enhance user experience through intelligent hardware and software solutions. The company collaborates with installers, technology providers, and energy companies to reach homeowners and promote the integration of clean energy technologies.
Omada Health, Inc. is a digital healthcare company that creates online programs aimed at managing chronic conditions. Founded in 2011 and headquartered in San Francisco, with an additional office in Atlanta, Omada Health helps employers and health plans identify individuals at risk for preventable chronic diseases such as prediabetes, diabetes, hypertension, and heart disease. The company offers personalized programs that adapt to the needs of participants, including services for diabetes prevention and management, hypertension, behavioral health, and musculoskeletal issues. By integrating professional health coaching, connected devices, real-time data, and personalized feedback, Omada Health strives to empower individuals to engage with their health and achieve sustainable lifestyle changes. It is recognized as the largest provider of the National Diabetes Prevention Program by the CDC.
Somatus is a healthcare company that partners with health plans, health systems, and nephrology, and primary care groups. It provides integrated care for patients with or at risk of developing kidney disease. Somatus' is vertically integrated clinical services and technology delay or prevent disease progression, improve quality and care coordination, and increase the use of home dialysis modalities and rates of kidney transplantation.
The company is headquartered in McLean, Virginia, and founded by a team of world-class healthcare operators, successful entrepreneurs, and leading clinicians treating kidney disease.
Synthego is a genome engineering company that enables the acceleration of life science research and development in the pursuit of improved human health.
The company leverages machine learning, automation, and gene editing to build platforms for science at scale. With its foundations in engineering disciplines, the company’s full-stack platform vertically integrates proprietary hardware, software, bioinformatics, chemistries, and molecular biology to advance both basic research and therapeutic development programs.
By providing both commercial and academic researchers and therapeutic developers with unprecedented access to cutting-edge genome engineering, Synthego is at the forefront of innovation, accelerating the development of truly engineered biology.
The company was founded in 2012 and is based in Redwood City, California.
Creditas is a financial technology company based in São Paulo, Brazil, specializing in secured consumer loans. Founded by Sergio Furio, the company operates a digital platform that leverages credit scoring and borrower assets, such as homes and automobiles, as collateral to provide loans. This approach allows Creditas to offer affordable lending solutions by partnering with traditional financial institutions and utilizing investor-backed resources. The platform is designed to enable borrowers to repay their loans in manageable installments, thereby making financing more accessible.
CodeSee is a developer of cloud-based data visualization software that facilitates a comprehensive understanding of code for developers and development teams. By analyzing the data flowing through a system, CodeSee creates an updated map of the system architecture, its components, and their interconnections. This allows developers to explore their codebase at both a high level and in detail, enhancing their ability to grasp how code and functionality relate to one another. The platform aims to transform developers from feeling like outsiders to becoming high performers, thereby expediting the development process and improving overall productivity.
Go Digit General Insurance Limited is a digital insurance company based in Bengaluru, India, founded in 2016 by Kamesh Goyal. The company offers a wide range of insurance products, including car, travel, home, commercial vehicle, bike, health, mobile, and shop insurance, as well as flight delay coverage. Go Digit focuses on enhancing customer experience through its online platform, which facilitates claims, renewals, and provides information on motor vehicle and health insurance. The company is known for its innovative approach to insurance, aiming to simplify products and pricing processes. It operates as a subsidiary of Go Digit Infoworks Services Private Limited and generates significant revenue from its motor insurance offerings.
Dave Inc. is a financial services company based in Los Angeles, California, founded in 2015. The company has developed a mobile application designed to assist users in managing their finances by providing insights into bank overdrafts and predicting expenses. The app enables users to avoid overdraft fees and low balances by offering features such as paycheck advances, budgeting tools, and resources for finding side gigs. With a focus on helping users maintain financial stability, Dave serves approximately 7 million Americans by providing essential tools for budgeting and credit building. The application is accessible on both the App Store and Google Play, positioning Dave as a key player in the challenger bank space.
Rokt is a leading provider of e-commerce technology that enhances the customer buying experience by integrating marketing into the transaction moment. The company works with prominent brands like Live Nation, Groupon, and GoDaddy to deliver tailored advertising at critical points during the purchasing process. This approach enables e-commerce businesses to boost brand engagement, unlock new revenue streams, and improve overall customer experiences. Founded in Sydney, Rokt has expanded its operations globally, serving clients across various regions, including North America, Europe, and Asia. Its proprietary technology aims to connect advertisers with customers at opportune moments, facilitating effective upselling and cross-selling opportunities while keeping businesses competitive in the rapidly evolving e-commerce landscape.
Anchorage is a crypto-native Qualified Custodian catering to institutional investors, providing a secure platform for trading, staking, and governance of digital assets. Founded in 2017 by former security engineers from Square and Docker, the company is headquartered in San Francisco, California. Anchorage has developed a regulated platform that emphasizes security and usability, facilitating simple participation in digital assets while ensuring robust custody solutions. The firm has attracted significant funding from prominent investors and serves a clientele that includes many of the largest and most recognized names in the cryptocurrency industry, positioning itself as a leader in the space.
Olist is an online e-commerce platform based in Curitiba, Brazil, that facilitates connections between sellers and major Brazilian marketplaces. Founded in 2015, the company provides a comprehensive platform for shopkeepers of various sizes and sectors to register and sell their products through prominent retailers. Olist aims to streamline the selling process for entrepreneurs by enabling them to advertise and sell their products without complications, thereby enhancing their reach to international marketplaces. The company emphasizes a sustainable and fair business model, focusing on delivering excellent services to both merchants and consumers.
Learneo brands and platforms are pioneering advances in a wide range of applications for emergent technologies, including the use of AI to improve people's writing, reading and math skills, in school, professional and daily life. The platform of businesses includes CliffsNotes, the original and iconic study guide company; Course Hero, an online learning platform of academic resources; LitCharts, a creator of literature resources; QuillBot, an AI-powered writing companion helping anyone improve their writing skills; Scribbr, a multilingual academic proofreading service, and Symbolab, an AI-based mathematics resource. Learneo was established in Redwood City, California by Andrew Grauer and Gregor Carrigan.
Chroma Medicine is a genomic medicine company focused on epigenetic editing to transform the treatment of genetically driven diseases. By leveraging epigenetics, which regulates gene expression naturally, Chroma Medicine aims to develop innovative therapies that provide precise control over gene activity. The company utilizes programmable epigenetic editors that combine DNA binding domains with epigenetic effector domains, allowing for targeted manipulation of genes and chromatin structure. This approach promises to create a new class of therapeutics that offers unparalleled control over gene expression, potentially leading to more effective treatments for a range of genetic disorders.
Faire Wholesale, Inc. operates an online marketplace that connects independent retailers with manufacturers, facilitating the purchase of unique wholesale merchandise. Founded in 2016 and headquartered in San Francisco, California, with an additional office in Kitchener, Canada, Faire streamlines the wholesale process by offering a platform where retailers can browse items, place orders, and track shipments. The marketplace employs artificial intelligence and predictive analytics to help retailers manage inventory effectively and reduce risks associated with unsold products. Faire provides features such as net 60 payment terms and free returns, which support local retailers and independent brands in competing with larger retail chains and e-commerce platforms. The company aims to empower small business owners by delivering technological solutions, data insights, and logistical support to enhance the future of local retail.
SaltPay is a FinTech company dedicated to building a better future for merchants by servicing them through payment and management tools. Focused on efficiency, technology, and people, they give merchants the help they need to grow.
Acrivon Therapeutics is a clinical-stage biopharmaceutical company focused on developing oncology medicines tailored to individual patients. The company employs a proteomics-based platform to identify patients whose tumors are likely to respond to specific treatments, thereby enhancing the effectiveness of drug development. Acrivon's lead program is ACR-368, also known as prexasertib, which is currently in Phase 2 trials. Additionally, the pipeline includes preclinical programs that target critical components of the DNA Damage Response and cell cycle regulation pathways, specifically focusing on proteins such as WEE1 and PKMYT1. By leveraging these innovative approaches, Acrivon aims to improve therapeutic outcomes for cancer patients.
BetterUp Inc. is a leadership development platform based in San Francisco, California, founded in 2013. The company provides a mobile-based solution for organizations, including Fortune 500 companies, aimed at enhancing employee performance through a science-backed methodology. BetterUp's platform facilitates on-demand virtual coaching sessions, allowing users to identify and practice new behaviors and mindsets essential for achieving high performance in a rapidly changing environment. The platform tracks and measures individual growth, helping employees cultivate skills that support both personal and professional development. Its diverse clientele includes notable companies like Genentech, Logitech, and Workday, reflecting its commitment to fostering an adaptive workforce.
Ventyx Biosciences, Inc. is a biotechnology company based in Encinitas, California, focused on developing selective inhibitors of TYK2 for the treatment of autoimmune diseases. Incorporated in 2018, the company boasts a diverse portfolio of innovative clinical and pre-clinical programs aimed at high-value therapeutic targets. Through its research and development efforts, Ventyx is committed to advancing treatments that address unmet medical needs in the autoimmune disease space.
Archaea Energy is an emerging leader in developing renewable natural gas (“RNG”) which is a sustainable decarbonizing solution for high-carbon emission processes and industries that are impossible or inefficient to electrify.
Arcadia, Inc. is a clean energy technology company that provides a platform connecting subscribers to wind farms and community solar projects across the United States. Founded in 2014 and based in Washington, D.C., the company enables users to sign up for clean energy options available in their area and receive compensation when matched with a clean energy source. Arcadia's platform allows customers to manage their accounts, track energy usage, and access monthly billing, facilitating a seamless experience for households and businesses. By aggregating clean energy supply and integrating data across utilities, Arcadia aims to enhance user engagement and control over energy consumption while promoting sustainable energy solutions.
SpotOn is a payments and software company that aims to transform the merchant services industry by combining payment processing with customer engagement tools. Founded in 2017 and headquartered in San Francisco, California, SpotOn provides a cloud-based platform specifically designed for small and medium-sized businesses. This platform includes a range of comprehensive tools such as payments, point-of-sale systems, custom website creation, appointment scheduling, marketing, customer reviews, analytics, and loyalty programs. By facilitating effective communication and allowing merchants to import existing customer lists, SpotOn enhances business efficiency and empowers merchants to make informed decisions while improving their marketing strategies. The company's commitment to exceptional customer service further supports its mission to help businesses thrive.
Asher Biotherapeutics, Inc. is a biotechnology company focused on developing immunotherapy drugs for cancer treatment. Founded in 2019 and headquartered in South San Francisco, California, the company aims to create innovative therapeutic solutions to improve patient outcomes in oncology. Asher Bio leverages advanced technologies and research to enhance the effectiveness of immune-based therapies, positioning itself as a key player in the evolving field of cancer treatment.
Trove AI, Inc. develops a mobile email application. The company develops artificial intelligence (AI) solutions that solve email overload and enhance communications. Its AI solution offers smart multi-swiping and email notifications; surfaces insights about user’s relationships; and lets snoozing emails to get them out of the user’s way until the user is ready to get to them. The application works with existing email services. Its mobile application is compatible with iOS and Android devices. The company was formerly known as Notion AI, Inc. Trove AI, Inc. was founded in 2013 and is based in Ann Arbor, Michigan.
Strata Oncology is a precision oncology company focused on enhancing cancer care through increased access to clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, Strata develops a comprehensive oncology platform that facilitates routine genomic testing and the efficient use of molecular data. Its offerings include The Strata Trial, a genomic testing protocol aimed at implementing enterprise-wide precision oncology; StrataNGS, a targeted assay for sequencing DNA and RNA from biopsy samples; and StrataPOINT, which integrates electronic medical record data with molecular profiling to ensure eligible patients are tested and considered for precision trials. Additionally, the company manages Strata Partnered Trials, a collection of pharmaceutical-sponsored protocols linked to specific biomarkers, and operates The Strata Lab, a cancer sequencing facility. Through its collaborative network of cancer centers, Strata is dedicated to advancing precision medicine for patients with cancer, ultimately providing actionable insights for healthcare providers.
Lucid Motors Inc. is an electric vehicle manufacturer based in Menlo Park, California, with a manufacturing facility in Casa Grande, Arizona. Founded in 2007 and initially known as Atieva, Inc., the company rebranded to Lucid Motors in 2016. Lucid Motors aims to enhance the driving experience by creating vehicles that prioritize performance, space, and intelligence. The company emphasizes intuitive design and user experience, striving to redefine mobility by focusing on the individual needs of drivers. To support its electric car production, Lucid Motors has established strategic partnerships with prominent battery manufacturers Samsung SDI and LG Chem.
Provider of counseling and psychiatric services intended to provide mental healthcare. The company offers services to a variety of life issues including depression, anxiety, relationship issues, low self-esteem, trauma and other mental health concerns, ensuring its clients with customized plans for their mental well-being.
BlackBuck is an online fleet management platform that connects shippers with fleet operators in India. By leveraging technology, it aims to enhance the logistics landscape, making it more reliable and efficient. The platform provides features such as price discovery, route optimization, in-transit tracking, and assurance of timely deliveries. This comprehensive approach not only improves operational productivity for clients but also positively impacts the broader transportation ecosystem, which is crucial for numerous livelihoods. BlackBuck is positioned to drive significant advancements in the transportation sector.
Sundae operates a home-selling platform designed to assist homeowners in selling houses that are outdated or in need of repairs. The company addresses the challenges faced by sellers in a traditional real estate market, where local investors often exploit homeowner distress to acquire properties at low prices. Sundae aims to provide a better outcome for these sellers by offering competitive off-market prices without the need for cleanup, repairs, or showings. Through a data-driven model, Sundae anticipates when homeowners may require assistance and employs a skilled sales and marketing team to effectively reach them. By prioritizing the needs of sellers and redistributing economic value, Sundae strives to become a leading buyer of homes that require significant attention across the United States.
HYZON Motors Inc manufactures hydrogen-powered trucks and buses. It offers city and coach buses, medium duty trucks, and heavy duty trucks. The company was founded in 2020 and is based in Honeoye Falls, New York.
Markforged, founded in 2013 and based in Watertown, Massachusetts, specializes in designing and manufacturing advanced 3D printers that utilize materials such as carbon fiber, metal, fiberglass, nylon, and PLA filament. The company's printers are engineered to produce durable parts, tooling, fixtures, and functional prototypes suitable for industrial applications. Markforged also offers EIGER, its proprietary 3D printing software, which enhances the printing process. With a global workforce of approximately 300 employees, the company has attracted significant investment, totaling around $137 million. Markforged has garnered recognition for its innovative contributions to manufacturing, including being featured in Forbes' Next Billion-Dollar Startups list and ranking as one of the fastest-growing hardware companies in the United States according to Deloitte's Fast 500.
Swiggy is an on-demand food delivery platform that connects users with local restaurants, allowing them to order food conveniently through a mobile app. Founded in 2014 by Sriharsha Majety, Nandan Reddy, and Rahul Jaimini, the company is headquartered in Bangalore, Karnataka, India. Swiggy offers a comprehensive list of nearby restaurants and their menus, enabling users to track their orders in real-time. In addition to food delivery, Swiggy also provides services for picking up and dropping off various items, such as laundry and parcels, catering to both business clients and retail customers. The platform emphasizes speed and convenience, ensuring that users receive their food fresh and on time, often accompanied by discounts.
EVgo Services LLC operates the largest public fast charging network for electric vehicles in the United States, providing a comprehensive infrastructure for both consumers and businesses. Founded in 2010 and based in Los Angeles, the company maintains over 1,100 fast chargers and more than 1,000 Level 2 chargers across 66 metropolitan markets in 34 states. EVgo's stations are compatible with all fast charge-capable electric vehicle models and can deliver up to 90 miles of range in just 30 minutes. The company collaborates with various partners, including grocery stores, automotive manufacturers, hotels, and local governments, to strategically deploy its charging stations. EVgo offers flexible pricing models such as Pay As You Go and membership options, ensuring accessible and convenient charging solutions for electric vehicle drivers.
Working with the world’s largest mobile game companies, ironSource is developing the industry's leading growth engine for games. With a robust mobile ad mediation platform, mobile ad network, and a data-driven user acquisition platform, ironSource closes the monetization and marketing loop to empower game developers to turn their games into successful businesses.
Payoneer Inc. operates a cross-border payments platform designed to facilitate global commerce by connecting businesses, professionals, countries, and currencies. Founded in 2005 and headquartered in New York, the company offers products such as the Global Payment Service, which provides users with local receiving accounts in the United States, European Union, and Japan, allowing for direct local bank transfers. Additionally, Payoneer enables users to receive payments from various integrated partners, including those in freelance, e-commerce, and online advertising sectors. The company also provides mass payout services that assist Indian companies in transferring funds internationally. Serving millions of users across over 200 countries, Payoneer is a trusted partner for numerous prominent corporations, making cross-border payments as straightforward as local transactions.
Perella Weinberg Partners is a privately owned investment management and financial services firm established in 2006 and headquartered in New York City. The firm operates primarily through two business units: corporate advisory and asset management. It provides corporate advisory services to various sectors, including consumer, retail, energy, financial services, healthcare, industrials, technology, media, and telecommunications, assisting clients with mergers, acquisitions, restructuring, and capital raising. In its asset management division, Perella Weinberg manages investment vehicles for institutional investors, including charitable organizations and pooled investment vehicles. The firm offers a diverse range of investment strategies, including equity, fixed income, multi-asset portfolios, hedge funds, and mutual funds, while investing globally in public equity, fixed income markets, distressed securities, private investments, and real estate. The firm employs fundamental analysis and in-house research to inform its investment decisions. It maintains additional offices in various locations, including Denver, Abu Dhabi, Dubai, London, and San Francisco.
Lendbuzz, Inc. is a car financing platform based in Boston, Massachusetts, established in 2015. It specializes in providing car loans to individuals with limited U.S. credit history, including international students, expats, and foreign professionals. The company utilizes machine learning algorithms and data-intensive scoring technology to assess creditworthiness based on factors such as employment, education, and personal history, rather than traditional credit scores or the requirement of a Social Security Number. This innovative approach allows Lendbuzz to offer attractive loan terms to customers who are often overlooked by conventional lenders. Once approved, clients can purchase vehicles from any dealership and work toward building their U.S. credit history while managing their loans through an online platform.
Faire Wholesale, Inc. operates an online marketplace that connects independent retailers with manufacturers, facilitating the purchase of unique wholesale merchandise. Founded in 2016 and headquartered in San Francisco, California, with an additional office in Kitchener, Canada, Faire streamlines the wholesale process by offering a platform where retailers can browse items, place orders, and track shipments. The marketplace employs artificial intelligence and predictive analytics to help retailers manage inventory effectively and reduce risks associated with unsold products. Faire provides features such as net 60 payment terms and free returns, which support local retailers and independent brands in competing with larger retail chains and e-commerce platforms. The company aims to empower small business owners by delivering technological solutions, data insights, and logistical support to enhance the future of local retail.
Latch is a New York-based company that enhances access management for modern buildings through its innovative keyless entry security systems. The company offers a comprehensive solution that allows property owners to manage all doors within multi-family buildings via a smartphone application. This system also enables residents to grant time-limited access to guests and service providers, improving convenience and security. LatchOS, the software platform developed by the company, operates across North America, serving diverse environments from affordable housing to luxury residential towers. Latch collaborates with a range of real estate developers, from large corporations to local property owners, to improve the living, working, and visiting experiences in various types of buildings.
NiKang Therapeutics, Inc. is a biotechnology company established in 2017 and located in Wilmington, Delaware. The company is dedicated to discovering and developing innovative small molecule oncology medicines aimed at addressing unmet medical needs in cancer treatment. By employing a discovery approach that leverages target structure biology and structure-based drug design, NiKang Therapeutics aims to facilitate the rapid and efficient development of proprietary drug candidates with optimal pharmacological properties. The company seeks to enhance the treatment options available to healthcare providers, ultimately improving patient outcomes in the fight against cancer.
Snapdocs, Inc. is a real estate technology company that provides a digital platform designed to streamline the mortgage closing process. Founded in 2012 and based in San Francisco, California, Snapdocs connects lenders, title and escrow companies, notary publics, and home buyers to enhance collaboration and efficiency in real estate transactions. The platform features advanced automation and standardized workflows, allowing participants to choose their preferred closing methods while improving accuracy and consumer satisfaction. It also enables notary signing agents to showcase their qualifications, helping them attract potential clients. By simplifying mortgage loan closings and improving the overall borrower experience, Snapdocs empowers its users to operate more effectively and transparently in a competitive market.
Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer. Leveraging deep expertise in structure-based design, Nuvalent develops innovative small molecules with exquisite target selectivity to overcome resistance, minimize adverse events, and drive more durable responses. It is advancing a robust pipeline with parallel lead programs in ROS1-positive and ALK-positive NSCLC, along with multiple discovery-stage research programs. It was founded in 2017 and is based in Cambridge, Massachusetts.
Oxford Nanopore Technologies Limited specializes in the development and commercialization of nanopore-based electronic systems for the analysis of single molecules, particularly in the fields of DNA and RNA sequencing. The company offers a range of products, including the portable MinION device for molecular analysis, the benchtop PromethION for large-scale sequencing projects, and the GridION system suitable for various molecular sensing applications. Their technology supports diverse scientific research areas such as genomics, cancer studies, microbiology, and environmental research, with applications extending to healthcare, agriculture, and food safety. The Flongle device caters to on-demand sequencing needs, while the MinIT accessory enhances the functionality of their sequencing devices. Oxford Nanopore’s innovative technology emphasizes accessibility and ease of use, with rapid library preparation and automated processes. Founded in 2005 and headquartered in Oxford, United Kingdom, the company operates additional offices worldwide, enabling its products to be utilized in over 80 countries.
Boundless Bio, Inc., biopharma company, develops therapies and medicines for the treatment of cancers. It offers therapeutics based on extrachromosomal DNA (ecDNA) one of the drivers of the aggressive cancers, such as cancers characterized by high copy number amplification of oncogenes. The company was formerly known as Pretzel Therapeutics, Inc. Boundless Bio, Inc. was founded in 2018 and is based in LA Jolla, California.
UrbanClap Technologies India Pvt. Ltd., now known as Urban Company, operates a leading online platform for home services in Asia, facilitating connections between customers and service professionals. Launched in November 2014 and based in Gurugram, India, the platform offers a diverse range of services, including beauty treatments, massage therapy, cleaning, plumbing, carpentry, appliance repair, and painting. Users can easily find and hire professionals such as wedding photographers, fitness trainers, and interior designers, among others. The platform provides features that allow customers to compare quotes, review profiles, and assess the experience of service providers. Urban Company serves major cities including Delhi NCR, Bengaluru, Mumbai, Chennai, Pune, and Hyderabad, and has expanded its reach to international markets like the UAE, Singapore, and Australia. The company is dedicated to empowering service professionals by offering them training, credit, and technological support.
Current is a leading U.S. challenger bank built to meet the needs of people with unique lives who have been overlooked by the traditional banking industry. Our proprietary Current Core technology allows us to provide premium banking services for everyone, regardless of age or income, and improve the financial outcomes of our members without overdraft fees, minimum balance requirements, or hidden fees. We give members up to two days faster direct deposit paychecks, free overdrafts up to $100 with Overdrive™ , points on purchases redeemable for cash back, access to 55,000 free ATMs worldwide as well as 24/7 member support 365 days a year.
Greenlight Financial Technology, Inc. is a financial services company that provides debit card solutions specifically designed for children, enabling parents to cultivate financial literacy in their kids. Founded in 2014 and headquartered in Atlanta, Georgia, Greenlight offers a mobile application that allows parents to manage their children's spending by selecting specific stores where the Greenlight debit card can be used. The platform features patent-pending technology that empowers parents to monitor spending habits, freeze cards if lost, receive instant alerts, and automate allowances. This approach not only promotes responsible spending but also facilitates teachable moments around earning, saving, and giving.
Scale AI, Inc. is a data platform that specializes in providing high-quality training and validation data for artificial intelligence applications. Founded in 2016 and based in San Francisco, the company offers a range of annotation tools, including platforms for 3D sensor data, images, videos, text, and documents. Its products support various AI tasks such as content moderation, transcription, and data comparison, and are utilized across multiple sectors including autonomous vehicles, retail, conversational AI, and robotics. Scale AI's technology enables companies to streamline their machine learning processes, allowing teams to concentrate on developing innovative models rather than the labor-intensive task of data labeling. The company serves notable clients in the technology and transportation industries, enhancing the efficiency and effectiveness of AI development.
Patreon Inc. operates a membership platform designed to help content creators and artists fund their work. Founded in 2013 and based in San Francisco, California, Patreon.com facilitates connections between users and provides access to various types of content, including videos, photographs, artwork, audio clips, and more. The platform allows patrons to pledge support to their favorite creators on a recurring basis, thereby empowering a new generation of artists to earn a living from their passions. By enabling direct financial support from fans, Patreon fosters a sustainable ecosystem for creative individuals to thrive.
Swiggy is an on-demand food delivery platform that connects users with local restaurants, allowing them to order food conveniently through a mobile app. Founded in 2014 by Sriharsha Majety, Nandan Reddy, and Rahul Jaimini, the company is headquartered in Bangalore, Karnataka, India. Swiggy offers a comprehensive list of nearby restaurants and their menus, enabling users to track their orders in real-time. In addition to food delivery, Swiggy also provides services for picking up and dropping off various items, such as laundry and parcels, catering to both business clients and retail customers. The platform emphasizes speed and convenience, ensuring that users receive their food fresh and on time, often accompanied by discounts.
Entrada Therapeutics, Inc., a biotechnology company, engages in the treatment of diseases through the intracellular delivery of biologic. The company enables intracellular delivery of proteins, peptides, and nucleic acids and allows development of programs across intracellular target classes. Its Intracellular enzyme replacement therapy (IC-ERT) is a medical treatment that corrects an enzyme deficiency in the cell, Protein-Protein Interaction Inhibitors. The company was founded in 2016 and is based in Boston, Massachusetts.
Paidy Inc. is a Tokyo-based company that offers a cardless payment platform designed for online shopping. Founded in 2008 and rebranded in 2018, Paidy allows consumers to make purchases using only their name and email address, eliminating the need for credit cards or pre-registration. The service is optimized for mobile and instant-checkout, facilitating a seamless shopping experience. Users can consolidate their purchases into a single monthly bill, enhancing convenience. Paidy employs proprietary technology to assess creditworthiness and underwrite transactions, providing merchants with guaranteed payments. This approach caters to Japanese consumers who prefer not to use credit cards, helping online vendors improve conversion rates, increase average order values, and encourage repeat purchases.
Scribe Therapeutics Inc. is a biotechnology company focused on developing innovative therapeutics using CRISPR technology to address genetic disorders. Founded in 2017 and based in Berkeley, California, Scribe specializes in engineering CRISPR enzymes known as X-Editing (XE) molecules, which enhance the efficacy, specificity, and deliverability of genome editing compared to existing methods. The company's proprietary platform enables the creation of custom-engineered enzymes and delivery systems, facilitating precision targeting within the genome. Scribe Therapeutics aims to establish CRISPR-based therapies as a standard in clinical care, expanding access to transformative treatments for a wide range of conditions, including immuno-oncology and degenerative disorders. Through its commitment to overcoming the limitations of current genome editing technologies, Scribe Therapeutics is poised to make substantial contributions to human therapeutics.
Cityblock Health, based in Brooklyn, New York, is a technology-driven healthcare provider focused on serving low-income urban communities with complex needs. Founded in 2017, the company aims to address the unmet health and social needs of Medicaid and Medicare populations through a personalized approach. Cityblock offers primary care, behavioral health, and virtual care services, emphasizing preventive care and mental health support. Its platform integrates communications and information sharing among care teams and members, facilitating better coordination of services. The company also collaborates with community-based organizations to enhance the delivery of care, ultimately seeking to improve health outcomes and reduce costs for its members.
Arrival Limited is a technology company based in London that specializes in manufacturing electric vehicles. Founded in 2015, the company focuses on developing software, materials, components, and scalable skateboard platforms, which serve as the foundation for its electric vehicles. Arrival's innovative approach includes the use of micro-factories, enabling efficient production and adaptation to various mobility ecosystems while minimizing capital expenditure. This model allows the company to produce zero-emission vehicles tailored to the needs of urban environments and aims to enhance public transportation through intelligent design. In addition to its headquarters in the United Kingdom, Arrival operates offices in Germany, the Netherlands, Israel, Russia, and the United States.
Ventyx Biosciences, Inc. is a biotechnology company based in Encinitas, California, focused on developing selective inhibitors of TYK2 for the treatment of autoimmune diseases. Incorporated in 2018, the company boasts a diverse portfolio of innovative clinical and pre-clinical programs aimed at high-value therapeutic targets. Through its research and development efforts, Ventyx is committed to advancing treatments that address unmet medical needs in the autoimmune disease space.
Artiva Biotherapeutics, Inc., a biotech company, develops and manufactures cellular immunotherapies for cancer patients. The company offers a pipeline of off-the-shelf, allogeneic natural killer (NK) cell therapies for the treatment of hematologic cancers or solid tumors. The company’s products target CD20 and CD19 in B-cell lymphomas and HER2 in various solid tumors. The company was founded in 2019 and is headquartered in San Diego, California. Artiva Biotherapeutics, Inc. operates as a subsidiary of Green Cross Holdings Corporation.
Butterfly Network designs a medical imaging device that reduces the cost of real-time and three-dimensional imaging and treatment. Jonathan M. Rothberg, Nevada Sanchez, and Tyler S. Ralston founded it in 2011, with its headquarters in Guilford in Connecticut.
Centessa Pharmaceuticals is a clinical-stage biopharmaceutical company focused on transforming the drug development process through an asset-centric research and development model. The company advances a diverse portfolio of validated programs, each managed by a dedicated subsidiary and backed by a centralized infrastructure and experienced management team. Among its pipeline assets are SerpinPC, targeting Hemophilia A and B, LB101 for solid tumors, ORX750 for narcolepsy type 1 and other sleep disorders, and MGX292 for pulmonary arterial hypertension. Additionally, Centessa is developing an undisclosed asset for solid tumors.
Gemini Therapeutics, Inc. is a precision medicine company established in 2015 and based in Cambridge, Massachusetts. The company specializes in developing therapies for patients with dry age-related macular degeneration (AMD) and related rare genetic diseases. Gemini's approach focuses on addressing genetically-defined conditions by creating therapeutic candidates that target specific molecular abnormalities prevalent in patients with significant clinical needs. Their diverse pipeline features a range of innovative treatment modalities, including monoclonal antibodies, recombinant proteins, and gene therapies. The company has secured funding from prominent life science investors and collaborates with academic institutions globally to advance its mission of delivering potentially first-in-class therapeutics.
Design Therapeutics, Inc. is a clinical-stage biotechnology company based in Solana Beach, California, focused on developing innovative therapies for degenerative disorders resulting from nucleotide repeat expansions. Founded in 2017, the company is advancing its lead program aimed at treating Friedreich's ataxia, while also exploring treatment options for other conditions such as Fragile X syndrome and myotonic dystrophy. Design Therapeutics is known for its GeneTACTM molecules, a new class of small-molecule gene-targeted therapies designed to address the underlying causes of diseases linked to inherited nucleotide repeat expansion mutations. The company's ongoing research efforts seek to develop disease-modifying treatments for serious conditions driven by these genetic factors.
Private Equity Round in 2021
PPRO is a fintech company founded in 2006, specializing in providing digital payment solutions for businesses and banks. Headquartered in the UK, PPRO simplifies access to a diverse range of payment methods required by consumers and businesses globally. The company offers an integrated platform that includes services such as credit card payment processing, alternative payment options, local cash collection, e-money accounts, and e-wallet facilities. PPRO is licensed by the FCA to issue e-money and is a principal member of major card networks, including Mastercard and VISA. The company's goal is to enhance local payment services through a single connection, thereby streamlining the payment process, boosting conversion rates, and facilitating the management of various payment methods for its clients.
Verve Therapeutics is a biotechnology company focused on developing innovative therapies aimed at editing the adult human genome to provide lifelong protection against coronary artery disease, a leading global cause of mortality. Founded in 2018 and based in Cambridge, Massachusetts, with a research facility in Philadelphia, the company employs gene-editing technology to create treatments that shift the management of cardiovascular diseases from chronic care to potentially curative interventions. Its initial programs concentrate on the PCSK9 and ANGPTL3 genes, which are recognized for their roles in regulating blood lipids, specifically low-density lipoprotein cholesterol. Verve Therapeutics collaborates with partners such as Beam Therapeutics and Verily to enhance delivery technologies for its cardiovascular treatments.
Billtrust develops a payment cycle management platform designed to automate every step in the invoice-to-cash process. Its platform accelerates cash flow by automating invoice delivery, invoice payment, and cash application for remarkable cost savings, ease-of-use, and improved customer satisfaction rates, enabling businesses and corporate clients to improve operational efficiency. The company was founded in 2001 and is headquartered in Lawrenceville, New Jersey.
Affinivax, Inc. is a biotechnology company based in Lexington, Massachusetts, that specializes in developing vaccines using its innovative Multiple Antigen Presenting System (MAPS) technology. This approach allows for the combination of protective polysaccharides and proteins in a single vaccine, aiming to enhance the immune response against various infectious diseases. Affinivax focuses on a range of pathogens, including Streptococcus pneumoniae, which poses significant health risks to both children and adults. The company seeks to create vaccines that provide broader disease coverage and address infectious diseases lacking effective immunization strategies. Founded in 2014, Affinivax benefits from insights provided by leading experts in infectious diseases and vaccines, and it has secured support from the Bill & Melinda Gates Foundation, along with exclusive licensing rights from Boston Children’s Hospital for its MAPS technology.
Scorpion Therapeutics, Inc. is a biotechnology company focused on developing next-generation precision oncology technologies aimed at improving cancer treatment. Founded in 2020 and based in Boston, Massachusetts, the company specializes in creating precision oncology drugs that target known oncogenes, address currently undruggable cancer targets, and explore new therapeutic targets. By integrating advanced technologies in target discovery, medicinal chemistry, and translational medicine, Scorpion Therapeutics seeks to expand the reach of precision medicine to a broader patient population. The company's approach is designed to unlock novel small-molecule drugs that can overcome the limitations of existing therapies, thereby enhancing treatment options for cancer patients.
Porch.com, Inc. operates an online platform that connects homeowners with local home repair services, facilitating the arrangement of setup and installation for purchased goods. The company serves as a resource for home improvement professionals and helps homeowners make informed decisions about home projects. Porch is available nationwide through its website and mobile app, and it is also the exclusive in-store resource in over 1,720 Lowe's locations across the United States. In addition to its core services, Porch offers a tool called Service Attach, which allows customers to add installation or assembly services to their online shopping carts. The company has a strategic partnership with Cinch Home Services Inc. Established in 2011, Porch is headquartered in Seattle, Washington.
Creditas is a financial technology company based in São Paulo, Brazil, specializing in secured consumer loans. Founded by Sergio Furio, the company operates a digital platform that leverages credit scoring and borrower assets, such as homes and automobiles, as collateral to provide loans. This approach allows Creditas to offer affordable lending solutions by partnering with traditional financial institutions and utilizing investor-backed resources. The platform is designed to enable borrowers to repay their loans in manageable installments, thereby making financing more accessible.
Cityblock Health, based in Brooklyn, New York, is a technology-driven healthcare provider focused on serving low-income urban communities with complex needs. Founded in 2017, the company aims to address the unmet health and social needs of Medicaid and Medicare populations through a personalized approach. Cityblock offers primary care, behavioral health, and virtual care services, emphasizing preventive care and mental health support. Its platform integrates communications and information sharing among care teams and members, facilitating better coordination of services. The company also collaborates with community-based organizations to enhance the delivery of care, ultimately seeking to improve health outcomes and reduce costs for its members.
Edgewise Therapeutics is a clinical-stage biopharmaceutical company based in Boulder, Colorado, specializing in the development of small molecule therapies for severe musculoskeletal diseases. Founded in 2017, the company leverages its expertise in skeletal muscle physiology to create innovative treatments for genetically defined muscle disorders, including Duchenne, Becker, and limb girdle muscular dystrophies. Edgewise Therapeutics employs a precision medicine platform to identify and target key muscle proteins and modulators, aiming to address the underlying causes of these conditions. Additionally, the company has established a state-of-the-art research facility to enhance its capabilities in understanding muscle adaptation and injury related to disease.
Current is a leading U.S. challenger bank built to meet the needs of people with unique lives who have been overlooked by the traditional banking industry. Our proprietary Current Core technology allows us to provide premium banking services for everyone, regardless of age or income, and improve the financial outcomes of our members without overdraft fees, minimum balance requirements, or hidden fees. We give members up to two days faster direct deposit paychecks, free overdrafts up to $100 with Overdrive™ , points on purchases redeemable for cash back, access to 55,000 free ATMs worldwide as well as 24/7 member support 365 days a year.
LianBio is a biopharmaceutical company based in Shanghai, China, with an additional office in Princeton, New Jersey. Founded in 2019, the company focuses on the discovery and development of therapeutic drugs aimed at treating oncology and cardiorenal diseases, as well as other medical conditions. LianBio's mission is to enhance access to innovative medicines by partnering with leading organizations in the field to leverage advanced scientific discoveries. The company is dedicated to addressing unmet medical needs in Greater China and other Asian markets by in-licensing assets and building a diverse pipeline of clinically validated product candidates. Its portfolio aims to establish new standards of care across various therapeutic areas, including cardiovascular, oncology, ophthalmology, inflammatory diseases, and respiratory conditions.
Scopely, Inc. is a global interactive entertainment company specializing in the development and publishing of mobile games for both casual and core gamers. Founded in 2011 and headquartered in Culver City, California, Scopely offers a diverse portfolio of immersive gaming experiences based on original and popular franchises, including titles such as Star Trek Fleet Command, Looney Tunes World of Mayhem, WWE Champions, and The Walking Dead: Road To Survival. The company is recognized for its innovative approach, having been featured in Fast Company’s ‘World’s Most Innovative Companies’ and ranked among the fastest-growing companies in North America. Scopely has achieved over $1 billion in lifetime revenue by focusing on long-lasting game experiences. It operates globally with studios in various locations, including Los Angeles, Barcelona, Dublin, and Tokyo, and provides services in game design, marketing, analytics, and live operations through its proprietary technology platform.
Gracell Biotechnologies Inc. is a clinical-stage biopharmaceutical company based in Shanghai, China, focused on discovering and developing innovative cell therapies for cancer treatment. The company's lead product candidates include GC012F, a dual-targeted CAR-T therapy for multiple myeloma currently in Phase I trials; GC019F, which targets adult B cell acute lymphoblastic leukemia and is also in Phase I trials; and GC007F, aimed at B cell non-Hodgkin’s lymphoma, also in Phase I. Additionally, Gracell is developing GC027, a CAR-T candidate targeting adult T cell acute lymphoblastic leukemia, and GC007g, an allogeneic CAR-T therapy for relapsed or refractory B-ALL, both in Phase I trials. Beyond these, Gracell has a pipeline of earlier-stage product candidates targeting various cancers, including ovarian and breast cancer. Founded in 2017, Gracell Biotechnologies is committed to advancing cellular therapeutics to improve patient outcomes in hematological malignancies and solid tumors.
Lordstown Motors Corporation is an American automobile manufacturer of electric vehicles.Lordstown Motors is completing the engineering and development of the first full-electric pickup truck.
Nuvation Bio Inc., a biopharmaceutical company, focuses on the development of therapies for oncology. Its portfolio includes various oncology programs with multiple drug development candidates. Nuvation Bio Inc.was formerly known as RePharmation Inc. and changed its name to Nuvation Bio Inc. in April 2019. The company was founded in 2018 and is based in New York, New York with an additional office in San Francisco, California.
Olema Oncology is a clinical-stage biopharmaceutical company dedicated to developing targeted therapies for women's cancers, particularly estrogen receptor (ER)-positive breast cancer. The company's lead candidate, OP-1250, is an ER antagonist and selective ER degrader currently undergoing Phase 1/2 clinical trials for the treatment of metastatic or locally advanced, ER-positive, and human epidermal growth factor receptor 2-negative breast cancer. Olema's research focuses on utilizing its expertise in endocrine-driven cancers and the molecular mechanisms of the ER to create more effective treatments that aim to improve patient outcomes. In addition to OP-1250, Olema is advancing another drug candidate, OP-3136, further enriching its pipeline. Established in 2006 and headquartered in San Francisco, California, Olema is committed to transforming the standard of care for women facing these challenging diagnoses.
Novellus is a biotechnology company working to develop engineered cellular medicines. The company uses its non-immunogenic mRNA molecules to reprogram and gene-edit cells safely, and with high efficiency. They engineer precision medicines for patient segments and select from its technology toolbox for in vivo, ex vivo, allogeneic and autologous delivery. Novellus platform enables the high-level expression of gene-editing and cell-reprogramming proteins for high-specificity gene repair and both autologous and allogeneic cell therapies. The company is advancing its lead program, a breakthrough therapy for a rare dermatologic disease, through pre-clinical studies. Novellus was founded in 2015 and is headquartered in Cambridge, Massachusetts, United States.
Attentive Mobile, Inc. is a personalized mobile messaging platform that enables companies to effectively acquire, retain, and engage with their mobile audiences. Founded in 2016 and headquartered in New York, the company serves a diverse range of industries, including e-commerce, retail, food and beverage, travel, hospitality, entertainment, media, publishing, education, and non-profit sectors. By leveraging real-time behavioral data, Attentive automates the delivery of tailored text messages throughout the customer lifecycle, which includes product recommendations, special promotions, payment notifications, and real-time customer service. With over 2,000 clients, including well-known brands like Sephora and Urban Outfitters, Attentive has demonstrated significant effectiveness, achieving impressive metrics such as over 30% click-through rates and more than 25 times return on investment.
NovellusDx, Ltd. is a biotechnology company based in Jerusalem, Israel, established in 2011 by Haim Gil-ad and Yoram Altschuler. The company specializes in developing targeted therapies for cancer patients by focusing on tumor-specific driver mutations. NovellusDx utilizes innovative testing methods to evaluate the effectiveness of targeted therapy drugs on emulated tumors, allowing for the quantification of therapeutic effects. The company also monitors the oncogenic activity of relevant genes and proteins in patients, assessing changes before and after drug administration. Additionally, NovellusDx develops assays to detect the misregulated translocation of mutated signaling proteins to the nucleus, measuring the impact of drug candidates on specific tumors, particularly concerning their ability to inhibit the translocation of up-regulated signaling proteins.
Affirm is a financial technology company that offers installment loans to consumers at the point of sale, allowing them to make purchases from online merchants and pay for them in fixed monthly installments. Founded in 2012 and headquartered in San Francisco, with an additional office in Chicago, Affirm aims to provide transparent financial products that empower consumers and enhance their buying experience. Customers can select Affirm as a payment method at checkout, complete a real-time application, and choose a payment plan that aligns with their budget. The service stands out by offering upfront pricing with no hidden fees or compounding interest, unlike traditional credit options. Affirm partners with over 2,000 merchants across various sectors, including retail, travel, and electronics, to provide consumers with a flexible alternative to credit cards. Loans are facilitated through a partnership with Cross River Bank, ensuring a reliable financing option for users.
E-Scape Bio, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule therapies for neurodegenerative diseases. Established in 2015 and headquartered in South San Francisco, California, the company aims to improve the lives of patients suffering from conditions such as Alzheimer’s disease, Parkinson’s disease, and sphingolipid storage disorders. E-Scape Bio is advancing a pipeline of therapeutics that target specific genetic drivers of these diseases, including ESB1609, a small molecule S1P5 receptor agonist for CNS lysosomal storage disorders, and ESB5070, a kinase inhibitor designed for Parkinson’s disease patients with the LRRK2 G2019S variant. Additionally, the company is developing a program targeting ApoE4 in Alzheimer’s disease, emphasizing its commitment to precision medicine in treating genetically defined subpopulations.
Patreon Inc. operates a membership platform designed to help content creators and artists fund their work. Founded in 2013 and based in San Francisco, California, Patreon.com facilitates connections between users and provides access to various types of content, including videos, photographs, artwork, audio clips, and more. The platform allows patrons to pledge support to their favorite creators on a recurring basis, thereby empowering a new generation of artists to earn a living from their passions. By enabling direct financial support from fans, Patreon fosters a sustainable ecosystem for creative individuals to thrive.
Skillz operates as a marketplace platform that connects mobile gamers, allowing them to discover and compete in various games against players globally. The company supports game developers in creating lucrative franchises by integrating social competition into their offerings. Utilizing patented technology, Skillz has facilitated over 2 billion tournament entries for approximately 30 million players worldwide, distributing over $60 million in prizes monthly. Notable games on its platform include Dominoes Gold, Blackout Bingo, 21 Blitz, and Solitaire Cube. Skillz primarily generates revenue through its eSports gaming platform, which enables developers to monetize their content via multiplayer competitions. The company's operations are mainly concentrated in the United States, with additional revenue from regions such as Israel, China, and Malta. Skillz has garnered recognition in the industry, being listed among Fast Company's Most Innovative Companies and CNBC's Disruptor 50, among other accolades.
Synthego is a genome engineering company that enables the acceleration of life science research and development in the pursuit of improved human health.
The company leverages machine learning, automation, and gene editing to build platforms for science at scale. With its foundations in engineering disciplines, the company’s full-stack platform vertically integrates proprietary hardware, software, bioinformatics, chemistries, and molecular biology to advance both basic research and therapeutic development programs.
By providing both commercial and academic researchers and therapeutic developers with unprecedented access to cutting-edge genome engineering, Synthego is at the forefront of innovation, accelerating the development of truly engineered biology.
The company was founded in 2012 and is based in Redwood City, California.
Dyne Therapeutics, Inc., a muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It develops various programs for myotonic dystrophy type 1, duchenne muscular dystrophy, and facioscapulohumeral dystrophy, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapies. The company was founded in 2017 and is based in Waltham, Massachusetts.
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.
Olema Oncology is a clinical-stage biopharmaceutical company dedicated to developing targeted therapies for women's cancers, particularly estrogen receptor (ER)-positive breast cancer. The company's lead candidate, OP-1250, is an ER antagonist and selective ER degrader currently undergoing Phase 1/2 clinical trials for the treatment of metastatic or locally advanced, ER-positive, and human epidermal growth factor receptor 2-negative breast cancer. Olema's research focuses on utilizing its expertise in endocrine-driven cancers and the molecular mechanisms of the ER to create more effective treatments that aim to improve patient outcomes. In addition to OP-1250, Olema is advancing another drug candidate, OP-3136, further enriching its pipeline. Established in 2006 and headquartered in San Francisco, California, Olema is committed to transforming the standard of care for women facing these challenging diagnoses.
VelosBio, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, focused on developing innovative antibody-drug conjugates (ADCs) to treat hematological cancers and solid tumors. The company specializes in therapies targeting receptor tyrosine kinase-like orphan receptor 1 (ROR1), a cell-surface protein commonly found in various tumors but absent in normal tissues, making it a promising target for cancer treatment. Its lead product, VLS-101, is designed as a ROR1-directed ADC aimed at patients with both hematologic and solid tumor malignancies. Founded in 2017, VelosBio has demonstrated positive preclinical results for its ROR1-directed therapeutics, paving the way for potential use in monotherapy or in combination with other treatments across a wide range of cancers. As of late 2020, VelosBio operates as a subsidiary of Merck & Co., Inc.
Goldfinch Bio, Inc. is a clinical-stage biotechnology company dedicated to discovering and developing precision therapies for kidney diseases. The company focuses on researching and commercializing treatments for conditions such as focal segmental glomerulosclerosis, diabetic nephropathy, and polycystic kidney disease. Notable programs include GFB-887, a selective inhibitor of the TRPC5 channel, and GFB-024, a cannabinoid receptor 1 inverse agonist. Goldfinch Bio is also developing the Kidney Genome Atlas, a genomic registry aimed at identifying new disease targets and biomarkers, and utilizes a biology platform that leverages stem cell science to create human organoid models for target validation. Founded in 2016 and based in Cambridge, Massachusetts, Goldfinch Bio has established a strategic collaboration with Gilead Sciences to enhance its capabilities in kidney disease therapy development.
Freeline Therapeutics is a clinical-stage biotechnology company focused on developing liver-directed gene therapies for bleeding disorders and other diseases. Based in Stevenage, United Kingdom, Freeline's lead product candidate, FLT180a, is undergoing Phase 1/2 clinical trials aimed at treating moderate to severe hemophilia B. The company's pipeline also includes FLT190, which is in dose-escalating Phase 1/2 trials for Fabry disease, FLT201 for type 1 Gaucher disease, and FLT210 for hemophilia A. Freeline utilizes a next-generation proprietary adeno-associated virus (AAV) vector platform, enhancing its potential for systemic gene therapy applications. Since its founding in 2015, the company has been dedicated to advancing innovative treatments in the field of gene therapy.