Consortium For Technology & Innovation in Pediatrics

Renata Medical is a company dedicated to developing innovative medical devices aimed at addressing the needs of children born with congenital heart disease (CHD). The company focuses on creating solutions that are both safe and versatile, specifically targeting unmet congenital needs in pediatric healthcare. One of its key products is an adjustable stent designed to be inserted at birth, which grows with the child, thereby reducing the necessity for multiple invasive surgeries over time. This approach not only enhances the quality of care for congenital patients but also minimizes the associated costs and risks of ongoing surgical interventions.

Rhaeos is a pioneering company that has developed the world's first wearable shunt monitor, designed to enhance the quality of care for patients with hydrocephalus. Utilizing a novel thermal biosensor, Rhaeos addresses a critical clinical need by offering noninvasive, wireless patches that detect fluid flow in various bodily systems, including blood, lymph, and cerebrospinal fluid. This innovative technology enables timely treatment for chronic medical conditions, particularly in the field of neurosurgery. Founded through collaborative efforts at Northwestern University, Rhaeos exemplifies a multidisciplinary approach, integrating expertise from engineering, medicine, and management to advance patient care.

Stark Street Materials is a manufacturer of radiation shielding garments and materials, founded in 2018 and headquartered in Portland, Oregon. The company develops non-toxic, washable, flexible shielding solutions that use bismuth particles instead of lead salts, delivering safer, more comfortable protection for medical personnel and other users exposed to radiation. Its lightweight, foldable and elastic designs aim to improve mobility while maintaining effective shielding, supporting diverse applications where radiation exposure is a concern. By combining safety with practicality, Stark Street Materials positions itself as a provider of versatile shielding materials and garments tailored to professional and industrial settings.

Nanodropper develops a universal eyedrop bottle adaptor that reduces the volume of oversized eye drops, lowering waste and medication costs. The product focuses on patient-centered design to address barriers in eye disease management, enabling healthcare providers, payers, and patients to minimize waste and optimize dose delivery across multiple bottle types.

Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.

Gus Gear is a manufacturer of wearable securement clothing designed to protect implanted medical devices and enhance patient outcomes. The company's flagship product, the Central Line Vest, safeguards central catheters from damage, breakage, and accidental removal, allowing patients to maintain their quality of life while undergoing treatment. In addition to the Central Line Vest, Gus Gear's platform offers securement solutions for various medical devices, including ostomy pouches and feeding tubes. By using innovative securement systems, Gus Gear enables patients to manage their medical challenges effectively, promoting independence and wellbeing.

Oratel Diagnostics, established in 2006 and based in Hammondsport, New York, specializes in developing diagnostic tools for mammalian fertility using plant pigment chemistry. The company's initial product is an ovulation detection test designed for dairy cattle, with plans to extend this technology to other livestock. Additionally, Oratel has developed saliva-based diagnostic devices that employ plant pigments to identify endometriosis and other reproductive disorders in women, aiding physicians in distinguishing pelvic pain causes and resolving fertility issues.

Founded in 2015, Cast21 specializes in developing innovative medical orthopedic products. Its flagship product is a waterproof and breathable cast designed for fracture and joint care, allowing patients to maintain hygiene without compromising healing. The company's unique design also accommodates electronic therapies to potentially reduce recovery time.

Gabi SmartCare is a medical technology startup developing predictive at-home monitoring solutions for early diagnostics and daily management of chronic respiratory diseases in children aged zero to twelve. Its platform monitors and diagnoses respiratory issues, enabling healthcare professionals to provide optimal care.

Linear Health Sciences is a medical device company focused on developing innovative products for medical tubing, utilizing its proprietary breakaway safety-valve technology. This technology aims to prevent unwanted disconnections during medical procedures, thereby enhancing the healthcare experience for patients, caregivers, and healthcare facilities. Founded by a physician and two engineers, the company has made significant strides in securing global patent protections and pursuing FDA clearance for its flagship product, the Orchid Safety Release Valve. With a total addressable market exceeding $1 billion annually, Linear Health Sciences is positioned to address critical needs in patient care and safety within the healthcare industry.

Luminoah is a medical device company that develops a closed-loop, personalized enteral nutrition platform. This platform aims to enhance chronic disease care by offering a compact wearable pump, smart nutrition consumables, a patient-facing mobile app, and a provider intelligence platform. These tools enable real-time monitoring of patients' progress and improve adherence across both home and clinical environments.

Eclipse Regenesis is a development-stage medical device company dedicated to leveraging the body’s natural tissue regeneration capabilities to address critical health issues. The company’s primary focus is on its flagship product, the Eclipse XL1 System, which employs distraction enterogenesis to mechanically stimulate the body’s production of new, fully-functional intestinal tissue. This innovative approach aims to provide a treatment for Short Bowel Syndrome, a condition characterized by significant nutritional malabsorption due to insufficient functional small intestine. Backed by over 15 years of scientific research and collaboration with leading experts in the field, Eclipse Regenesis is committed to pioneering a restorative therapy for patients suffering from this currently incurable disease. The Eclipse XL1 System remains an investigational device and is not yet available for commercial use.

Seattle Children's is dedicated to providing hope, care, and cures to ensure that every child can lead a healthy and fulfilling life. As a pediatric and adolescent academic medical center, it serves a vast region encompassing Washington, Alaska, Montana, and Idaho, making it the largest children's hospital network in the United States. The organization is committed to delivering exceptional patient care while advancing pediatric research to develop new treatments and innovations. Through its comprehensive approach, Seattle Children's strives to meet the diverse health needs of children in its expansive service area.

SpineX Inc. is a clinical-stage medical device company focused on developing non-invasive neuromodulation technologies for individuals with neurological conditions. The company aims to address unmet medical needs by creating devices that support recovery and restoration of functions such as bladder, bowel, respiration, sexual, and sensorimotor capabilities. Their flagship device, the SCiP, is designed to treat neurological dysfunctions, particularly related to conditions like cerebral palsy. SpineX's commitment to advancing neuromodulation therapy stems from its goal to enhance the quality of life for patients recovering from strokes, spinal cord injuries, multiple sclerosis, traumatic brain injuries, and other related ailments.

Omaroon Corporation specializes in manufacturing a rapid at-home blood test system for patients diagnosed with Phenylketonuria (PKU), a rare genetic disorder. Their innovative platform monitors and addresses amino acid levels, empowering individuals with PKU to better manage their condition, improve dietary control, and enhance their overall quality of life through real-time data and personalized feedback.

Biomotum is a company that specializes in the design and development of wearable robotic exoskeletons aimed at enhancing mobility for individuals facing challenges in walking due to health issues. The company's innovative systems integrate advanced assistive technology with user-friendly therapeutic features, providing real-time training insights and compatibility with tele-rehabilitation. Biomotum's products are particularly beneficial for those affected by neurologic disorders such as stroke and cerebral palsy, offering embedded progress reporting to facilitate effective rehabilitation. Through its focus on empowering mobility, Biomotum addresses the growing need for solutions that support individuals with mobility impairments.

Hemex Health, Inc. specializes in developing and manufacturing medical diagnostic devices aimed at populations at risk for malaria and sickle cell disease. Founded in 2016 and based in Portland, Oregon, the company offers innovative products such as the Magneto-Optical Device (MOD), which detects all strains of malaria in under a minute, and the HemeChip, designed to identify hemoglobin disorders. Additionally, Hemex Health provides the SMART solution for early detection of sickle cell disease and malaria through point-of-care testing, enabling healthcare professionals in both clinical and field settings to deliver rapid and affordable diagnostics. The company's portable devices allow physicians, small laboratories, and frontline healthcare workers to diagnose and treat these diseases more efficiently, thereby improving patient outcomes in underserved regions.

Rubitection Inc., founded in 2010 and based in Pittsburgh, Pennsylvania, specializes in developing tools for early skin health assessment and management. Their primary product is the Rubitect Assessment System, which aids caregivers, doctors, and nurses in detecting early signs of bedsores on an individual's skin. The company's mission is to establish a global standard system for monitoring and managing skin health, particularly focusing on wound care, dermatology, and cosmetics. Rubitection's handheld device is designed to be low-cost and easy to use, enabling anyone to monitor their skin health and identify conditions such as bedsores, diabetic foot ulcers, vascular leg ulcers, and chronic dermatological conditions early. The device includes features like risk analytics, remote monitoring, care plan management, and severity progression monitoring to assess tissue health effectively.

Lactation Lab analyzes breast milk samples to provide mothers with detailed nutritional insights. Their user-friendly reports help moms understand the composition of their milk, promoting informed decisions about infant nutrition.

Founded in 2017 and headquartered in Baltimore, Maryland, Sonavi Labs is a medical technology company that develops innovative devices and software. It specializes in analyzing body sounds for disease diagnosis, utilizing artificial intelligence to enhance healthcare provider capabilities.

Lightengale is a medical device company focused on enhancing patient safety in healthcare settings, particularly in intensive care units. The company develops innovative devices that utilize light-emitting cables to illuminate individual intravenous (IV) lines from the pump to the patient. This technology addresses the critical issue of line mix-ups, which can lead to medication delivery errors. By facilitating clearer visualization of IV lines, Lightengale's devices empower nurses to trace and manage infusions more effectively, ultimately allowing them to dedicate more time to patient care. The company’s commitment to improving clinical outcomes underscores its role in advancing medical practices within the healthcare industry.

Enosis is developing new technologies for immersive storytelling, VR and Whole Body Interaction.

MedMxr produces an autoinjector that separates drug components until time of use, mixes the components, and injects the medication safely.

Myka Labs develops innovative procedural technologies focused on high-need conditions in gastrointestinal and other organ systems. Their AI-driven platform assists pediatric surgery teams in treating complex conditions, enhancing patient outcomes.

Karios Technologies is a developer of innovative hydrogel technology aimed at addressing significant unmet needs in surgery, drug delivery, and regenerative medicine. The company's primary focus is on the prevention of postsurgical adhesions, which can lead to complications after surgery. Their hydrogel product, once applied, binds to the heart muscle and transforms into a soft, elastic coating that serves as a protective barrier. This technology is designed to reduce postsurgical complications while allowing for necessary movement, making it applicable in various surgical fields, including cardiac, obstetric, gynecologic, and orthopedic applications. Through its advancements, Karios Technologies seeks to enhance patient outcomes by minimizing the risks associated with surgical procedures.

Ezalife manufactures medical equipment that reduces the risk of post-operative complications for children and adults.

Starlight Cardiovascular specializes in developing innovative medical devices tailored for pediatric congenital heart disease, addressing the limitations of current tools designed for adult patients. Their mission is to enhance morbidity and mortality outcomes, and improve access to care for young patients.

Ostiio develops an innovative bone distraction system designed to correct skeletal deformities and deficiencies. Its fully implantable device is buried under the patient's skin, eliminating the need for external components, and features a programmable driver that enables remote monitoring and control by prescribing surgeons.

May & Meadow is a Redwood City, California-based medical technology company that develops digital health sensors and related software to assess feeding ability in infants at risk for feeding problems. Founded in 2015, the company provides timely, quantitative information to mothers and clinicians to enable objective assessments and informed decisions about feeding and breastfeeding. The sensor technology supports monitoring and guidance for addressing feeding difficulties, with the aim of improving outcomes for newborns and reducing caregiver anxiety.

Kangarobe manufactures comfortable robe that a parent wears during kangaroo care in the NICU.

iPill Dispenser was created to prevent unauthorized access to controlled substances. iPill is the opioid bank ATM. With a mobile app that only allows the prescribed person to access opioids at the prescribed dose, the iPill platform actively controls dispensing.

Happiest Baby, Inc. is a technology company focused on developing science-based products and services aimed at enhancing the health, safety, and emotional well-being of children. Founded in 2010 by Dr. Harvey Karp and Nina Montée-Karp, the company is headquartered in Los Angeles, California. Its flagship product, SNOO, is the world’s first smart sleeper, utilizing advanced robotic technology to implement Dr. Karp's 5 S's method for soothing infants. SNOO has received multiple international awards, including recognition from the National Sleep Foundation, and is part of the Smithsonian Institution's collection as a notable design innovation. Happiest Baby also offers a range of baby-related products, such as swaddles and educational materials, and provides resources for parents to address various childcare challenges. The company's mission is to support parents in raising healthy and happy children, with ongoing studies at leading medical centers exploring the benefits of its products in reducing postpartum depression and promoting safe sleep practices.

Securisyn Medical manufactures and supplies oxygen delivery systems for mechanically ventilated patients in critical care settings. Its innovative airway stabilization system, featuring a ribbed endotracheal tube and interlocking stabilizer, enhances patient safety by preventing unplanned extubation and reducing healthcare costs.

Prescient Surgical, Inc. is a medical device manufacturer focused on preventing surgical site infections. The company has developed CleanCision, a wound retraction and protection system that combines wound protection and irrigation to continuously clear harmful bacteria from surgical incisions. This innovative approach aims to enhance patient outcomes and reduce healthcare costs, particularly for patients undergoing high-risk abdominal gastrointestinal surgery. Established in 2012, Prescient Surgical is headquartered in San Carlos, California.

GattaCo LLC, established in 2018 and headquartered in Murrieta, California, specializes in medical diagnostics. The company has developed innovative, fully automatic diagnostic equipment designed to simplify and streamline sample collection and processing methods. Its flagship product, a disposable, high-yield rapid plasma separation and metering tool, aims to replace traditional centrifuges, enabling healthcare professionals to perform blood purification efficiently and cost-effectively.

ProMedix is a medical device startup based in Portland, Oregon, founded in 2019. The company specializes in the development of noninvasive, fingertip patient monitors aimed at enhancing the recognition of circulatory dysfunction. Its innovative devices are designed to assist in the diagnostic evaluation and monitoring of various medical conditions, such as trauma, dehydration, and sepsis. By facilitating effective home patient monitoring, ProMedix aims to simplify both home and critical care, helping physicians to prevent unnecessary acute visits and improve overall emergency and critical care outcomes.

Nictavi is a ophthalmological medical device startup that produces therapeutic devices for cornea care.

Aidar Health is a healthcare technology company specializing in digital therapeutics. Their flagship product, mouthlab, is a non-invasive, handheld device that measures vital signs such as temperature, blood oxygen saturation, breathing rate, pulse rate, ECG, and blood pressure through breath and saliva analysis. The device transmits data securely to the cloud for AI-driven analytics, enabling timely interventions and improved outcomes for patients with chronic diseases.

X-Biomedical specializes in advancing and commercializing innovative surgical visualization technologies. Its flagship product is GoScope, a portable dental microscope system designed to provide high-quality magnification for clinicians, enabling hands-free control through voice recognition.

Limbix is a company dedicated to developing prescription digital therapeutics for adolescent mental health. Their flagship product, SparkRx, is an evidence-based, clinically validated tool designed to treat depression and anxiety in teenagers. Limbix combines clinical expertise with technological innovation to deliver effective mental health treatments.

Melio is a healthcare company based in Santa Clara, California, specializing in blood testing technology aimed at detecting prevalent infections. The company has developed a comprehensive blood test platform that identifies common pathogens responsible for bloodstream infections. Utilizing a patented melting technique followed by detailed analysis, Melio's technology enables quick and accurate identification of blood-based pathogens. This innovation allows healthcare providers to deliver timely and targeted treatment, addressing the urgent need for effective therapies while also contributing to the fight against antibiotic resistance.

Diatech Diabetes is a MedTech startup focused on improving the lives of individuals with diabetes through innovative monitoring solutions. The company has developed SmartFusion, a sophisticated system designed for insulin pumps that enhances the accuracy of insulin delivery and detects infusion set failures. By integrating its software with existing insulin pumps, SmartFusion utilizes data from the pump, continuous glucose monitors, and the patient's infusion habits. This approach allows for personalized insulin management, enabling patients to better monitor their daily dosages and reduce the risk of complications. Diatech Diabetes aims to provide tailored solutions that address the unique needs of diabetes patients, ultimately promoting better health outcomes.

AudioCardio is a mobile application that provides personalized sound therapy aimed at protecting and enhancing natural hearing abilities while alleviating the effects of tinnitus. The app offers a daily one-hour therapy session that can be experienced with or without music. Utilizing evidence-based techniques, AudioCardio's technology focuses on remapping auditory pathways through neuroplasticity, stimulating the cells in the ear to help users maintain and improve their hearing.

BioSense is a developer of health and wellness monitoring systems. Their ECG sensors detect the ECG signal through multiple fabric and clothing layers without any skin contact. They design a non-contact ECG solution to read the body’s electrical heartbeat signal.

NeuroDetect operates as a biotechnology company that develops FDA-compliant software to advance precision-guided therapies for patients suffering from epilepsy. A diagnostic biomarker is used to detect or confirm the presence of a disease or condition of interest or to identify individuals. A predictive biomarker is used to identify individuals who are more likely to respond to exposure to a particular medical product or environmental agent.

BrainChild Technologies is a company based in Atlanta, Georgia, focused on enhancing parent-infant communication through innovative digital applications. The company has developed a smart pacifier designed to facilitate the early identification of hearing loss in infants. This device monitors an infant's sucking behavior in response to various stimuli, such as images or sounds, allowing for interactive engagement between parents and their children. By measuring behavioral data, BrainChild Technologies aims to support parents in recognizing potential hearing issues early, enabling timely interventions that can significantly improve outcomes for infants. The integration of educational games and applications further enriches the developmental experience for both parents and their children.

Senseer Health, founded in 2017, focuses on addressing the chronic disease market by developing Smart Medical Device Therapies for managing various chronic conditions, which affect a significant portion of older adults. The company's innovations began with patented microsensors that monitor implantable devices for patients with hydrocephalus, renal, and cardiovascular diseases. To enhance the effectiveness of these microsensor-enabled devices, Senseer has incorporated advanced wearable and ambient sensor technologies. The integration of these multi-modal sensor technologies with an IoT software platform allows for the utilization of proprietary data sets and predictive analytics. This comprehensive approach provides healthcare providers with tools for remote monitoring and timely interventions, ultimately aiming to improve the quality of life for individuals with chronic conditions while reducing costs and enhancing patient safety.

AMB Surgical is a medical device company focused on developing innovative solutions for pediatric deformities, particularly in the context of spine reconstruction. The company's flagship product is an electro-mechanical smart automated growing rod that allows for precise and frequent non-surgical adjustments, aided by sensor feedback. This technology is designed to assist surgeons in addressing complex cases of pediatric scoliosis, correction of complex deformities, and long bone lengthening, thereby enhancing treatment options and outcomes for young patients. Through its cutting-edge approach, AMB Surgical aims to improve the quality of care in the field of pediatric orthopedics.

Alerje, Inc. is a Detroit-based company focused on enhancing the quality of life for individuals with food allergies. Founded in 2015, Alerje has developed an innovative emergency medicine and digital oral immunotherapy management platform. Central to its offerings is an epinephrine auto-injector that conveniently fits into a smartphone case, promoting better adherence and alert management for users. The company also provides a mobile application that allows users to create personalized food allergy profiles, share these profiles with caregivers and medical professionals, and filter recipes based on allergen information. Additionally, the app includes features for scanning grocery items to identify potential allergens, thus aiding families and healthcare providers in making informed dietary choices. Alerje's platform is validated by the National Science Foundation and aims to improve emergency response and overall management of food allergies.

Neuromuscular Dynamics produces medical device that quantifies neuromuscular ability and tracks clinical recovery.

Wearable Sensing specializes in the development of advanced wearable brain monitoring solutions that cater to diverse applications such as augmented cognition, brain-computer interfaces, peak performance training, and health and wellness. The company offers a comprehensive platform featuring high-density, dry electrode EEG systems, as well as multimodal sensing capabilities that include electrocardiogram, electromyography, and electrooculogram technologies. These innovations are designed to support research and applications in areas such as neurofeedback, neuroeconomics, and neuromarketing. By providing researchers and developers with effective tools to capture and analyze neural data, Wearable Sensing enhances the ability to explore and understand brain activity in immersive environments.

Cubby Beds designs and manufactures smart safety beds for children and individuals with cognitive disabilities, including autism, epilepsy, and dementia. The beds incorporate a canopy with circadian lighting and soothing sounds, padded walls, securable doors, and a monitoring camera to create a calming, secure sleep environment that supports safer sleep, reduces anxiety, and addresses sensory needs for families.

Noninvasix, Inc., established in 2007, is a medical technology company based in Galveston, Texas. It develops non-invasive precision oximetry systems designed to measure oxygen sufficiency within organs and veins without the need for invasive catheters. The company's primary focus is on monitoring brain oxygenation in preterm babies within newborn intensive care units (NICUs). Noninvasix has raised over $6.8 million in funding, including a seed round in late 2021, and has been supported by grants from the NIH and DOD totaling $6 million. The company's technology has been clinically validated and is protected by a robust IP portfolio comprising 9 U.S. and 8 global patents. Noninvasix has participated in prestigious accelerator programs such as Philips Healthworks and TMCx, and its innovations have earned multiple awards.