The West Coast Consortium for Technology & Innovation in Pediatrics

Renata Medical is a healthcare company that specializes in developing innovative medical devices aimed at addressing congenital heart disease (CHD) in children. The company focuses on creating safe and versatile solutions to meet the unmet needs of patients born with this condition. Its flagship product is an adjustable stent designed to be inserted at birth, which grows alongside the child. This device significantly reduces the necessity for multiple invasive surgeries, thereby alleviating the financial and physical burdens associated with ongoing treatment. Through its commitment to innovation, Renata Medical aims to improve the quality of life for children with congenital heart disease.

Rhaeos is a pioneering company that has developed the first wearable shunt monitor to enhance care for patients with hydrocephalus. Utilizing a novel thermal biosensor, the device allows for noninvasive, real-time monitoring of cerebrospinal fluid flow. This innovative technology, born from collaborative research at Northwestern University involving experts from engineering, medicine, and management, addresses a significant clinical need by providing timely data to improve treatment for chronic medical conditions. Rhaeos's patches are designed to detect fluid flow in various bodily systems, including blood and lymph, facilitating quicker medical responses and advancing the standard of care in neurosurgery and beyond.

Stark Street Materials, founded in 2018 and based in Portland, Oregon, specializes in the development of radiation shielding garments designed to enhance safety for users exposed to radiation. The company focuses on creating non-toxic, washable, and lightweight materials that incorporate bismuth particles as a shielding element instead of traditional lead salts. This innovative approach allows for garments that are flexible, foldable, and elastic, providing medical personnel and other users with a more comfortable and effective means of radiation protection.

Nanodropper is a company that has developed a universal adaptor for eyedrop bottles, aimed at addressing the issues of medication waste and cost in eye disease management. The adaptor reduces the volume of oversized drops, allowing for more efficient use of eye medications. By minimizing waste, Nanodropper's product benefits healthcare providers, payers, and patients alike, ultimately improving adherence to prescribed treatments and making eye care more affordable.

Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.

Gus Gear specializes in the development and manufacturing of wearable securement clothing designed to protect implanted medical devices. The company's flagship product, the Central Line Vest, effectively prevents damage, breakage, and accidental removal of central catheters. By providing securement solutions for various medical devices, including ostomy pouches and feeding tubes, Gus Gear aims to enhance patient outcomes and quality of life. Their innovative approach enables patients to maintain a higher level of independence and well-being while undergoing medical treatment, allowing them to live their lives to the fullest despite any health challenges.

Oratel Diagnostics is a company that specializes in developing diagnostic tools for mammalian fertility using plant pigment chemistry. Founded in 2006 and based in Hammondsport, New York, the company has created an ovulation detection test for dairy cattle as its first product, with plans to extend its technology to other livestock. In addition to its agricultural applications, Oratel Diagnostics is also focused on medical diagnostics, specifically for women's health. The company's saliva-based assay devices are designed to detect endometriosis and other reproductive disorders by utilizing proprietary pigments that produce color responses indicating the presence of these conditions. By combining these assays with Web camera technology, Oratel Diagnostics aims to assist physicians in accurately diagnosing pelvic pain and addressing reproductive issues.

Cast21 is a medical product developer based in Memphis, Tennessee, focused on creating innovative orthopedic solutions for fracture and joint care. Established in 2015, the company has developed a waterproof and breathable cast designed to enhance patient comfort and facilitate recovery. Its unique design not only allows for skin hygiene—enabling patients to wash and scratch beneath the cast—but also supports the integration of electronic therapies aimed at reducing healing time. By prioritizing user experience and effective treatment, Cast21 seeks to improve the overall recovery process for individuals with orthopedic injuries.

Gabi SmartCare is a med-tech start-up focused on addressing the challenges of chronic respiratory diseases, which affect millions of children globally each year. The company develops innovative at-home monitoring solutions aimed at facilitating early diagnostics and daily management of these conditions. By leveraging data-driven technologies specifically designed for pediatric care, Gabi SmartCare enables healthcare providers to improve disease prevention, diagnosis, and surveillance. This approach not only enhances the quality of life for affected children but also seeks to alleviate the significant financial burden that respiratory diseases place on healthcare systems.

Linear Health Sciences is a medical device company focused on developing innovative products for medical tubing, utilizing its proprietary breakaway safety-valve technology. This technology aims to prevent unwanted disconnection of medical tubing, thereby enhancing the healthcare experience for patients, caregivers, and healthcare facilities. The company has made significant strides in securing global patent protections and obtaining FDA clearance for its flagship product, the Orchid Safety Release Valve. With a total addressable market exceeding $1 billion annually, Linear Health Sciences was founded by a physician and two engineers, emphasizing a strong blend of medical and engineering expertise in its product development efforts.

Luminoah is a medical device company focused on enhancing chronic disease care through its innovative enteral nutrition platform. The company has developed a wearable system that integrates durable medical equipment with consumable nutrition pouches. This platform allows for personalized enteral feeding, enabling doctors to remotely monitor patients and track feeding status online. By combining technology and nutrition, Luminoah aims to revolutionize the enteral feeding market and improve clinical outcomes for individuals requiring nutritional support.

Eclipse Regenesis is a development-stage medical device company dedicated to leveraging the body's natural tissue regeneration mechanisms to treat significant health conditions. The company is focused on its flagship product, the Eclipse XL1 System™, which employs distraction enterogenesis to mechanically stimulate the production of new, fully functional intestinal tissue. This innovative approach aims to address Short Bowel Syndrome (SBS), a condition that currently has no cure and leads to severe nutritional malabsorption due to insufficient functional small intestine. Supported by over 15 years of scientific research and collaboration with SBS experts globally, Eclipse Regenesis is committed to advancing restorative therapies for patients suffering from this challenging disorder. The Eclipse XL1 System is still investigational and not yet available for commercial use.

Seattle Children's is dedicated to providing hope, care, and cures to ensure that every child can lead a healthy and fulfilling life. As a pediatric and adolescent academic medical center, it serves a vast region encompassing Washington, Alaska, Montana, and Idaho, making it the largest children's hospital network in the United States. The organization is committed to delivering exceptional patient care while advancing pediatric research to develop new treatments and innovations. Through its comprehensive approach, Seattle Children's strives to meet the diverse health needs of children in its expansive service area.

SpineX Inc. is a seed-stage medical device company focused on developing non-invasive neuromodulation devices aimed at addressing unmet medical needs in patients with neurological conditions. The company is engaged in clinical trials to evaluate the safety and effectiveness of its neuromodulation therapy specifically for individuals suffering from neurogenic bladder issues related to stroke, spinal cord injuries, or multiple sclerosis. SpineX's technologies are designed to enhance recovery and restore various functions, including bladder, bowel, respiration, sexual, and sensorimotor capabilities. One of its key products, the SCiP device, targets neurological dysfunction associated with conditions like cerebral palsy. By leveraging rigorously tested neuromodulation methods, SpineX aims to improve the quality of life for individuals affected by these debilitating conditions.

Omaroon Corporation offers rapid at-home blood test system for patients with orphan disorder such as Phenylketonuria.

Biomotum specializes in the design and manufacturing of wearable robotic exoskeletons aimed at improving mobility for individuals facing challenges in walking. The company addresses the growing health issues related to mobility impairments, particularly for those affected by neurological disorders such as stroke and cerebral palsy. Biomotum's innovative systems integrate advanced assistive technology, offering a user-friendly therapeutic solution that features real-time training insights, compatibility with tele-rehabilitation, and built-in progress reporting. This approach enhances the rehabilitation process for users, empowering them to regain mobility and improve their quality of life.

Hemex Health, Inc. specializes in developing and manufacturing medical diagnostic devices aimed at populations at risk for malaria and sickle cell disease (SCD). Founded in 2016 and based in Portland, Oregon, the company offers innovative products such as the Magneto-Optical Device (MOD), which detects all strains of malaria in under a minute, and the HemeChip, designed to identify hemoglobin disorders. Additionally, Hemex Health provides the SMART platform, facilitating early diagnosis of SCD and malaria through point-of-care testing and mobile device registries within healthcare settings. These portable diagnostic devices enable physicians, small laboratories, and field healthcare workers to deliver timely and affordable medical diagnostics, significantly improving patient care in remote areas.

Rubitection Inc. is a company based in Pittsburgh, Pennsylvania, specializing in early assessment and management of skin health, particularly focusing on the prevention of bedsores and diabetic foot ulcers. Founded in 2010, Rubitection has developed the Rubitect Assessment System, a handheld device designed for caregivers, doctors, and nurses to detect early signs of skin issues. This system provides features such as risk analytics, remote monitoring, and care plan management, allowing users to measure changes in tissue properties and assess overall skin health. Rubitection aims to establish itself as the global standard for skin health monitoring and care management, applicable not only in wound care but also in dermatology and cosmetic fields.

Lactation Lab is a company that specializes in analyzing breast milk to assess its nutritional content. By providing insights into key components such as calories, protein, vitamins, DHA, and environmental toxins, Lactation Lab aims to reduce nutrition-related illnesses and support breastfeeding efforts. Their testing analysis kit delivers results in an accessible format resembling a food label, allowing mothers to understand the nutritional profile of their breast milk. This information empowers women to optimize their intake for better infant nutrition, fostering confidence through evidence-based insights and support derived from scientific research.

Sonavi Labs, Inc. is a Baltimore-based company that specializes in the development of medical devices and artificial intelligence-based software aimed at respiratory monitoring and diagnostic support. Founded in 2017, the company focuses on creating innovative products that analyze body sounds to assist in the diagnosis of respiratory diseases. By leveraging advanced technology, Sonavi Labs enables healthcare providers to detect, monitor, and potentially predict respiratory conditions by identifying abnormalities in the sounds produced by the body. This approach enhances the capabilities of medical professionals and aims to improve the patient experience in managing respiratory health.

Lightengale is a developer of medical devices focused on enhancing safety in healthcare settings, particularly in intensive care units. The company has created an innovative infusion line that utilizes light-emitting cables to illuminate individual intravenous (IV) lines from the pump to the patient. This design addresses the critical issue of line mix-ups and medication delivery errors, which can pose significant risks to patient safety. By providing visual cues for nurses to accurately trace IV lines, Lightengale's technology allows healthcare professionals to dedicate more time to patient care, ultimately improving the overall quality of medical treatment.

Enosis is developing new technologies for immersive storytelling, VR and Whole Body Interaction.

MedMxr produces an autoinjector that separates drug components until time of use, mixes the components, and injects the medication safely.

Myka Labs specializes in developing advanced interventional procedural technologies aimed at addressing high-unmet medical needs, particularly in gastrointestinal and other organ systems. The company focuses on AI-driven catheter systems that enhance patient care by integrating sophisticated multimodal sensor architectures, including miniature ultrasonic probes and positioning sensors. These innovative solutions are designed to facilitate interventional procedures for conditions such as pancreatic cancer and various disorders affecting the gastrointestinal tract and lungs. By overcoming longstanding challenges in the field, Myka Labs aims to improve treatment outcomes and extend the lives of patients.

Karios Technologies specializes in hydrogel technology aimed at preventing postsurgical adhesions, which are common complications following surgery. Their innovative product, when applied, adheres to the heart muscle and transforms into a soft, elastic coating that forms a protective barrier. This technology is designed for use in various surgical fields, including cardiac, obstetric, gynecologic, and orthopedic applications, helping to address significant unmet needs in surgery, drug delivery, and regenerative medicine. By reducing and preventing adhesions, Karios Technologies aims to enhance patient outcomes and minimize post-surgical complications.

Ezalife manufactures medical equipment that reduces the risk of post-operative complications for children and adults.

Starlight Cardiovascular focuses on creating medical devices specifically designed to address congenital heart disease in pediatric patients. Recognizing that existing treatments were predominantly developed for adults, the company aims to enhance the effectiveness of care for infants and children. Their portfolio includes regenerative and infection-resistant devices, particularly in the realm of cardiovascular patches, which facilitate improved clinical outcomes for substitute conduit arteries. By targeting the unique anatomical and physiological needs of young patients, Starlight Cardiovascular seeks to reduce morbidity and mortality rates, while also increasing access to essential medical care.

Ostiio is focused on developing an innovative bone distraction system aimed at correcting skeletal deformities and deficiencies. The company has created a fully implantable device that is buried beneath the patient's skin, eliminating the need for external components. This advanced system features a magnetically driven distraction mechanism that can be expanded with precision and monitored remotely by physicians. This programmability provides surgeons with enhanced transparency and control during the treatment process, addressing a longstanding challenge in skeletal correction. Ostiio operates as a company under the Penn Center for Innovation, emphasizing its commitment to advancing medical technology in orthopedics.

May & Meadow, Inc. is a company based in Redwood City, California, that focuses on developing medical devices aimed at assessing feeding abilities in infants at risk for feeding problems. Founded in 2015, the company specializes in digital health technologies that support mothers and newborns facing challenges related to feeding and breastfeeding. Its innovative sensor technology delivers timely and quantitative information to both mothers and healthcare providers, facilitating objective assessments and offering reassurance to families dealing with feeding difficulties.

Kangarobe manufactures comfortable robe that a parent wears during kangaroo care in the NICU.

iPill Dispenser was created to prevent unauthorized access to controlled substances. iPill is the opioid bank ATM. With a mobile app that only allows the prescribed person to access opioids at the prescribed dose, the iPill platform actively controls dispensing.

Happiest Baby, Inc. is a technology company based in Los Angeles, California, focused on enhancing the health, safety, and emotional well-being of children through innovative, science-based products and services. Founded in 2010 by pediatrician Dr. Harvey Karp and Nina Montée-Karp, the company is best known for its flagship product, SNOO, the world's first smart sleeper, which utilizes advanced robotic technology to soothe infants following Dr. Karp's 5 S's method. SNOO has received numerous accolades, including recognition from the National Sleep Foundation and inclusion in the Smithsonian Institution's collection. In addition to SNOO, Happiest Baby offers a range of products such as baby swaddles, sacks, and sheets, as well as educational resources on baby sleep and calming techniques. The company's mission is to support parents in raising healthy, happy children by addressing everyday parenting challenges with effective solutions.

Securisyn Medical, LLC is a medical technology company based in Highlands Ranch, Colorado, that specializes in the manufacture and supply of oxygen delivery systems for mechanically ventilated patients. Founded in 2011, the company focuses on enhancing patient safety and preventing unplanned extubation, which can lead to serious complications. Its innovative airway stabilization system features a ribbed endotracheal tube and an interlocking stabilizer, providing additional security for the airway and protecting critical components. Securisyn Medical serves healthcare providers and medical facilities across the United States, striving to reduce preventable deaths related to airway management while also decreasing overall healthcare costs. The company's commitment to ethical and sustainable practices underpins its mission to improve outcomes for patients, their families, and practitioners.

Prescient Surgical, Inc. develops medical devices aimed at preventing surgical site infections, specifically for patients undergoing high-risk abdominal gastrointestinal surgeries. The company's flagship product, CleanCision, features a wound retraction and protection system that integrates wound protection with continuous irrigation. This system effectively clears harmful bacteria that may invade surgical incisions, thereby enhancing patient outcomes and reducing healthcare costs. Incorporated in 2012, Prescient Surgical is based in San Carlos, California.

GattaCo is a medical diagnostics company that has created innovative technology aimed at enhancing sample collection and processing methods. The company specializes in fully automatic, disposable equipment designed for rapid plasma separation and metering, serving as a replacement for traditional centrifuges. This advancement enables healthcare professionals to conduct blood purification more efficiently and cost-effectively, thereby improving diagnostic outcomes and streamlining laboratory workflows.

ProMedix is a medical device startup founded in 2019 and headquartered in Portland, Oregon. The company specializes in developing noninvasive, fingertip patient monitors aimed at enhancing the recognition of circulatory dysfunction. Its innovative devices facilitate diagnostic evaluations and the monitoring of therapeutic interventions for various medical conditions, such as trauma, dehydration, and sepsis. By improving home patient monitoring, ProMedix enables physicians to streamline care in both home and critical settings, thereby preventing unnecessary acute visits and enhancing emergency or critical care outcomes.

Nictavi is a ophthalmological medical device startup that produces therapeutic devices for cornea care.

Aidar Health is a healthcare technology and digital therapeutics company that focuses on enhancing patient care through innovative solutions. The company has developed a non-invasive, hand-held device called mouthlab, which allows for rapid health assessments by measuring various health metrics, including temperature, blood oxygen saturation, breathing rate, pulse rate, ECG, and blood pressure, in under a minute. This device enables home monitoring of chronic disease patients, with real-time sensor data transmitted securely to a HIPAA-compliant cloud using LTE-M or Bluetooth. Aidar Health's proprietary analytics system employs artificial intelligence and machine learning to analyze this data, producing actionable insights that can be accessed through a physician portal. This facilitates timely interventions and adjustments to treatment plans, ultimately aiming to improve patient outcomes and reduce the risk of hospitalization for individuals with chronic conditions.

X-Biomedical is a company focused on advancing and commercializing innovative surgical visualization technology. It has developed a portable dental microscope system that enhances surgical procedures by delivering high-quality magnified images with exceptional clarity. This device features voice recognition for hands-free operation, allowing clinicians and dentists to maintain focus on their work while accessing detailed views of the oral cavity and surrounding anatomical structures. By improving visualization in dental practices, X-Biomedical aims to enhance the precision and effectiveness of surgical interventions.

Limbix is a prescription digital therapeutic company focused on developing mental health treatments specifically for adolescents. The company combines clinical expertise with technological innovation, leveraging a diverse team of clinicians, product designers, researchers, and engineers to create effective therapeutic solutions. Limbix's flagship product, SparkRx, is a digital therapeutic designed to assist licensed healthcare professionals in treating young patients dealing with depression, anxiety, and other mental health issues. By offering evidence-based interventions, Limbix aims to enhance the lives of teenagers facing mental health challenges.

Melio is a healthcare company based in Santa Clara, California, specializing in blood testing technology aimed at detecting prevalent infections. The company has developed a comprehensive blood test platform that identifies common pathogens responsible for bloodstream infections. Utilizing a patented melting technique followed by detailed analysis, Melio's technology enables quick and accurate identification of blood-based pathogens. This innovation allows healthcare providers to deliver timely and targeted treatment, addressing the urgent need for effective therapies while also contributing to the fight against antibiotic resistance.

Diatech Diabetes is a MedTech startup focused on improving the lives of diabetes patients through innovative monitoring solutions. The company has developed SmartFusion, a system designed for insulin pumps that enhances the accuracy of insulin delivery while detecting potential infusion set failures. By integrating its software with insulin pumps, SmartFusion utilizes an algorithm that processes data from the pump, continuous glucose monitors, and individual patient infusion habits. This personalized approach enables patients to effectively monitor their insulin dosages, reducing complications and tailoring treatment to their specific needs.

AudioCardio is a mobile application that offers personalized sound therapy aimed at protecting and enhancing natural hearing abilities while alleviating tinnitus symptoms. The app provides a daily one-hour session of sound therapy, which can be experienced with or without accompanying music. Utilizing evidence-based technology, AudioCardio works by remapping auditory pathways through a process known as neuroplasticity, stimulating the cells within the ear to promote hearing health. The platform is designed to be user-friendly, making it accessible for individuals seeking to improve their auditory well-being.

BioSense is a developer of health and wellness monitoring systems. Their ECG sensors detect the ECG signal through multiple fabric and clothing layers without any skin contact. They design a non-contact ECG solution to read the body’s electrical heartbeat signal.

NeuroDetect operates as a biotechnology company that develops FDA-compliant software to advance precision-guided therapies for patients suffering from epilepsy. A diagnostic biomarker is used to detect or confirm the presence of a disease or condition of interest or to identify individuals. A predictive biomarker is used to identify individuals who are more likely to respond to exposure to a particular medical product or environmental agent.

BrainChild Technologies is based in Atlanta, Georgia, and focuses on developing digital applications and smart devices aimed at enhancing parent-infant communication. The company's flagship product is a low-cost smart pacifier designed to improve the early identification of hearing loss in infants. This innovative device measures changes in an infant's sucking behavior in response to various images and sounds, enabling parents to engage in interactive activities with their children. By tracking behavioral data, BrainChild Technologies helps parents recognize potential hearing issues early, allowing for timely interventions that are crucial for effective treatment.

Senseer Health, founded in 2017, focuses on addressing the chronic disease market by developing Smart Medical Device Therapies for managing various chronic conditions, which affect a significant portion of older adults. The company's innovations began with patented microsensors that monitor implantable devices for patients with hydrocephalus, renal, and cardiovascular diseases. To enhance the effectiveness of these microsensor-enabled devices, Senseer has incorporated advanced wearable and ambient sensor technologies. The integration of these multi-modal sensor technologies with an IoT software platform allows for the utilization of proprietary data sets and predictive analytics. This comprehensive approach provides healthcare providers with tools for remote monitoring and timely interventions, ultimately aiming to improve the quality of life for individuals with chronic conditions while reducing costs and enhancing patient safety.

AMB Surgical specializes in developing innovative medical devices aimed at addressing complex spine reconstruction and pediatric deformities. The company is focused on creating an electro-mechanical smart automated growing rod that allows for precise and frequent non-surgical adjustments, supported by sensor feedback. This technology is designed to assist surgeons in treating conditions such as pediatric scoliosis, complex deformity correction, and long bone lengthening. Through its advanced platform, AMB Surgical aims to improve surgical outcomes and enhance the quality of care for young patients facing these challenging medical issues.

Alerje, Inc. is a company based in Detroit, Michigan, specializing in emergency medicine and digital oral immunotherapy management for individuals with food allergies. Founded in 2015, Alerje has developed an innovative epinephrine auto-injector designed to fit within a smartphone case, enhancing patient adherence and emergency response capabilities. The accompanying mobile application allows users to create personalized food allergy profiles, share this information with their CareCircle—comprising family, friends, caregivers, and medical professionals—and receive location alerts. Additionally, the platform enables users to filter recipes and scan grocery items for potential allergens, thereby improving dietary decision-making. Alerje's system has been validated by the National Science Foundation, emphasizing its commitment to enhancing the quality of life for those affected by food allergies.

Neuromuscular Dynamics produces medical device that quantifies neuromuscular ability and tracks clinical recovery.

Wearable Sensing specializes in the development of advanced wearable brain monitoring solutions that cater to various applications such as augmented cognition and brain-computer interfaces (BCI). The company offers high-density, dry electrode EEG systems alongside multimodal sensing capabilities, including electrocardiogram (ECG), electromyography (EMG), and electrooculogram (EOG). These technologies are designed for diverse fields such as neurofeedback, neuroeconomics, and neuromarketing, enabling researchers and developers to effectively capture and analyze neural data in immersive environments. Through its innovative platform, Wearable Sensing supports peak performance training and health and wellness initiatives, positioning itself at the forefront of wearable sensing technology.

Cubby Beds specializes in manufacturing smart safety beds designed to enhance the sleep experience for individuals with cognitive disabilities, including Autism, Epilepsy, and Dementia. These beds incorporate features such as a calming canopy equipped with circadian lighting and soothing sounds, padded walls for added safety, securable doors, and a monitoring camera. By creating a secure and comforting sleep environment, Cubby Beds aims to address the specific needs of children with special needs, helping families improve overall sleep quality and safety while providing sensory benefits.

Noninvasix, Inc. is a medical technology company based in Galveston, Texas, that specializes in non-invasive precision oximetry for measuring brain oxygenation in preterm infants within neonatal intensive care units. Founded in 2007 by Dr. Donald Prough and Dr. Rinat Esenaliev at the University of Texas Medical Branch, the company has developed a novel optoacoustic platform technology that allows for continuous monitoring of oxygen sufficiency in organs and veins without the need for invasive procedures. This technology is particularly useful in diagnosing and managing conditions such as sepsis and septic shock, enabling clinicians to assess tissue hypoxia in real-time and adjust treatments accordingly. Noninvasix has received over $6.8 million in funding, including substantial grants from the NIH and DOD, and has been recognized in various prestigious accelerator programs. The company's innovations have been validated in multiple peer-reviewed studies, and its intellectual property includes numerous patents both in the U.S. and internationally.