What If Ventures

Levels develops a health and wellness platform that monitors metabolic fitness by tracking blood glucose in real time, enabling users to optimize their diet and exercise. The company offers a wellness wearable device paired with a platform that provides real-time feedback on how the body responds to dietary and lifestyle choices, helping users tailor their routines to personal goals. Founded in 2019, Levels operates as a remote-first company focused on helping individuals understand their metabolism to improve health outcomes.

Legacy is a company focused on transforming male fertility through innovative testing and preservation solutions. Founded by healthcare and fertility experts, Legacy provides home-based kits that allow men to analyze, improve, and preserve their sperm without the need to visit a clinic. Their offerings include sperm analysis and cryogenic storage options, facilitating the preservation of fertility for clients in a straightforward and accessible manner. The company collaborates with leading hospitals, fertility clinics, and progressive employers to ensure high-quality services. Legacy has garnered recognition through various awards, including victories at TechCrunch Disrupt and MassChallenge Boston, and has attracted investment from notable firms such as Bain Capital Ventures and Section 32.

Grayce, Inc. is a health care agency based in San Francisco that specializes in providing personalized guidance and support for families caring for aging adults and children. Founded in 2019, the company offers a range of services designed to assist caregivers with various aspects of care, including insurance, finances, legal plans, medical care, home care, housing, daily needs, and overall well-being. Each member of Grayce receives dedicated support from a social worker who helps manage their comprehensive care needs by planning, prioritizing, identifying resources, coordinating care, and advocating on their behalf. Through its social care management platform, Grayce empowers family caregivers to navigate the complexities of caring for vulnerable loved ones.

Patient Sortal is a community-based organization focused on supporting individuals reintegrating into society after incarceration by providing essential healthcare services. It employs a blockchain-based data management system to digitize medical records and connect returning citizens with qualified healthcare providers seamlessly. By streamlining the process, Patient Sortal eliminates unnecessary duplicate assessments, appointments, and medication prescription refills, thereby reducing overall healthcare costs per patient. The organization emphasizes evidence-based, data-driven approaches to population health and care management, ensuring that individuals have access to continuous medical care during their transition back into the community. Through these efforts, Patient Sortal addresses critical healthcare challenges faced by this vulnerable population.

Frame develops an evidence-based platform for early detection of risk and care navigation to inform family building and planning. Its approach alleviates a downstream and often costly health crisis for patients, employers, and payers.

Affect Therapeutics offers an integrated digital treatment program for drug and alcohol addiction via a mobile app. The program uses contingency management and other reward systems to encourage healthy behaviors and new habits, aiming to improve member retention and better outcomes.

Sensate is a London‑based company that designs a palm‑sized wearable device and companion app to reduce stress, anxiety, and improve sleep and concentration. The device sits on the chest and delivers sub‑audible tones that stimulate the vagus nerve, providing real‑time relaxation. It is part of BioSelf Technology’s product line and offers a subscription service alongside the hardware.

Mimio Health is a nutraceutical company specializing in the research and production of mimetic supplements. Its patent-pending fasting mimetic formulation replicates the body's natural response to fasting by using a rigorously selected combination of bioactive human metabolites, inducing regenerative effects without requiring actual fasting.

Affect Therapeutics offers an integrated digital treatment program for drug and alcohol addiction via a mobile app. The program uses contingency management and other reward systems to encourage healthy behaviors and new habits, aiming to improve member retention and better outcomes.

Calibrate Health, Inc., established in 2020 and based in New York, specializes in digital metabolic health services for sustainable weight loss. The company combines FDA-approved metabolic medications with a comprehensive curriculum and personalized virtual coaching to address the root causes of weight issues and promote long-term behavior change. Calibrate's approach, led by experts in obesity and nutrition science, aims to improve metabolic health and drive lasting results.

Maximus is a consumer telemedicine company for men’s health and hormone optimization. Maximus is revolutionizing the performance enhancement space by democratizing doctor-prescribed protocols developed by some of the world’s leading experts in men’s health. Maximus’ King Protocol utilizes a convenient prescription medication capsule to stimulate natural testosterone production, proven by at-home lab tests. Maximus was established in 2020 by Cameron Sepah in Santa Monica, California.

Levels develops a health and wellness platform that monitors metabolic fitness by tracking blood glucose in real time, enabling users to optimize their diet and exercise. The company offers a wellness wearable device paired with a platform that provides real-time feedback on how the body responds to dietary and lifestyle choices, helping users tailor their routines to personal goals. Founded in 2019, Levels operates as a remote-first company focused on helping individuals understand their metabolism to improve health outcomes.

HealthRhythms develops a digital platform that assesses and monitors mental health conditions using deep machine learning and predictive analytics. Its solution offers real-time behavioral monitoring and personalized interventions, enabling healthcare providers to accurately measure mental health status and deliver timely care.

Human API is a health data network that facilitates the real-time sharing and viewing of health information across various platforms. Founded in 2013 and headquartered in San Mateo, California, the company connects consumers with their health data from a wide range of sources, including 90% of US hospitals, electronic medical records, pharmacies, labs, and over 300 wearable devices and wellness applications. The platform utilizes a machine learning-powered data pipeline to structure health data into a consistent format, making it accessible for medical researchers and scientists. Importantly, Human API empowers consumers by giving them full control over the sharing of their health information, while also providing companies with a streamlined method to access fragmented health data.

MiResource aims to improve global mental health by connecting individuals with appropriate mental healthcare services. Its platform facilitates connections between patients and licensed therapy providers, offering information on various treatment options such as one-on-one talk therapy, medication management, and intensive outpatient programs.

TRIPP is a digital wellness company that develops immersive experiences for virtual reality, augmented reality, and mobile devices to support emotional well-being. The platform combines mindfulness structures, sound frequencies, visuals, and interactive elements to influence mood—helping users feel calmer, more focused, and less stressed. Aimed at consumer households, TRIPP delivers these experiences through VR, AR, and mobile formats, grounded in research-based content. The company is headquartered in Los Angeles, California, with a satellite development office in Chicago.