ZeroTo510

ZeroTo510 is an entrepreneurial accelerator based in Memphis, Tennessee, established in 2012. It specializes in supporting medical device and healthtech startups by leveraging the region's strengths in medical device research and manufacturing. The program aims to assist these startups in navigating the complexities of the startup process, refining their business models, and achieving FDA's 510(k) premarket notification filing. ZeroTo510 offers a structured, mentorship-driven 90-day program that includes both instructional and hands-on activities tailored to guide entrepreneurs through the necessary steps. Additionally, selected companies receive up to $150,000 in seed funding to help them launch their ventures effectively.

Danielle Gore

Accelerator Director

Past deals in Tennessee

EndoShunt

Seed Round in 2022
EndoShunt Medical is a Nashville, Tennessee-based company founded in 2022 that specializes in developing medical devices for targeted hemorrhage control in emergency situations. The company has created a device designed to shunt blood past hemorrhaging vessels endovascularly, allowing surgeons to perform definitive repairs while maintaining blood flow. This innovative approach aims to enhance patient outcomes during critical medical emergencies by providing effective hemorrhage management.

Winter Innovations

Seed Round in 2019
Winter Innovations is a Knoxville, Tennessee-based startup founded in 2018 that focuses on developing medical devices aimed at enhancing patient outcomes in orthopedic care. The company is in the process of launching EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgery. This innovative device seeks to simplify and standardize the whip stitching technique, offering advantages such as ease of use, speed, stability, and versatility. Through these improvements, Winter Innovations aims to help surgeons perform orthopedic reconstruction procedures more efficiently and consistently.

Hera Health Solutions

Seed Round in 2018
Hera Health Solutions, Inc. is a biotechnology company focused on the development and commercialization of innovative drug delivery systems, particularly long-acting therapeutics. Founded in 2017 and headquartered in Frisco, Texas, the company specializes in biodegradable implants that release contraceptive hormones over time. Its flagship product, Eucontra, is designed to resorb into the body after delivering the medication, thereby simplifying the administration of contraceptives and improving patient adherence. By leveraging advanced materials and manufacturing techniques, Hera Health Solutions aims to transform the landscape of long-acting drug delivery and address healthcare accessibility issues.

Path Ex

Venture Round in 2017
Path Ex, Inc. is a Nashville, Tennessee-based company founded in 2017 that specializes in the manufacture of extracorporeal blood cleansing equipment. The company has developed a proprietary technology aimed at selectively separating and capturing bacteria and toxins from human blood, specifically for the treatment of sepsis, a critical condition often linked to blood-borne infections. Unlike conventional methods that rely on antibiotics to combat infections, Path Ex's innovative approach focuses on removing intact bacteria from the bloodstream, making it effective against various bacteria types and drug-resistant strains. This technology has the potential to significantly improve patient outcomes by reducing diagnostic times, lowering treatment costs, decreasing readmission rates, and ultimately decreasing sepsis-related mortality.

SOMAVAC Medical Solutions

Seed Round in 2016
SOMAVAC Medical Solutions, Inc. is a medical technology company based in Memphis, Tennessee, that specializes in enhancing post-operative care. Founded in 2016, the company develops innovative solutions aimed at improving recovery outcomes for patients undergoing various surgical procedures, particularly those at risk of seroma complications, such as breast surgeries and abdominoplasty. SOMAVAC Medical's flagship product, the SOMAVAC 100, is a sustained vacuum system designed to facilitate the removal of fluids and maintain tissue adhesion during recovery. By focusing on the challenges associated with surgical drains and fluid accumulation, SOMAVAC Medical Solutions aims to optimize the healing process and improve the overall patient experience following surgery.

Cast21

Seed Round in 2016
Cast21 is a developer of orthopedic medical products based in Memphis, Tennessee, that specializes in creating waterproof and breathable casts for fracture and joint care. Founded in 2015, the company focuses on innovative designs that enhance patient comfort and promote healing. Its products utilize lightweight materials that allow for skin care and hygiene while wearing the cast. Additionally, Cast21's designs facilitate the integration of electronic therapies to potentially reduce healing time, offering a modern solution for patients recovering from injuries.

SweetBio

Pre Seed Round in 2015
SweetBio, Inc. is a medical device company focused on the research, development, and manufacturing of innovative wound care solutions. Established in 2015 and headquartered in Memphis, Tennessee, SweetBio specializes in bioengineering membranes that incorporate medical-grade Manuka honey, which aids in healing and combating bacterial infections associated with various types of wounds, including surgical wounds, pressure ulcers, and diabetic ulcers. The company aims to revolutionize wound care by offering absorbable membranes that enhance the efficacy of treatments for both chronic and acute wounds, thereby improving patient outcomes for medical practitioners.

Blood Monitoring Solutions

Seed Round in 2014
Blood Monitoring Solutions, Inc. is a Memphis, Tennessee-based company that specializes in developing innovative blood monitoring systems aimed at reducing blood wastage. The company has created a smart blood transport system that enables blood banks to proactively monitor the temperature and presence of each blood unit. This data-driven technology ensures that blood is maintained within the correct temperature range, thereby preventing spoilage and enhancing patient safety. By improving the management of blood supplies, Blood Monitoring Solutions not only helps hospitals preserve blood for longer periods but also contributes to cost reductions in healthcare settings.

Better Walk

Seed Round in 2013
Better Walk Inc. is an innovative company based in Atlanta, Georgia, specializing in the design and development of crutches. Founded in 2013, the company aims to enhance the traditional crutch design by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. The organization emphasizes continuous innovation, recognizing the need for advancements in even the most established technologies. Better Walk gained early support through the Zero To 510 accelerator program in Memphis, Tennessee, which facilitated its initial funding. Since relocating to Atlanta in late 2014, the company has focused on refining its flagship product, the Better Walk crutch, and is preparing for its production and launch.

Restore Medical Solutions

Series A in 2012
Restore Medical Solutions, Inc., established in 2012 and based in Memphis, Tennessee, specializes in manufacturing modular sterilization tray systems for hospitals and surgery centers. Their products aim to reduce surgical site infections (SSIs), enhance safety, and improve productivity within the healthcare industry by minimizing the risk of contamination from medical instruments.

Urova Medical

Seed Round in 2012
Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on developing innovative solutions to address stress urinary incontinence in women. Founded in 2012, the company emerged from a project by undergraduate biomedical engineers at Johns Hopkins University, where its technology was refined with guidance from leading physicians at one of the top urological centers in the United States. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and safe treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which supports health-focused startups in the region.
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