Kyoto University Innovation Capital

Kyoto University Innovation Capital Co., Ltd. (Kyoto iCAP) is a venture capital firm established in December 2014, wholly funded by Kyoto University. Located in Kyoto, Japan, the firm focuses on providing investment and support to startups emerging from Kyoto University, with an emphasis on commercializing research outcomes and technologies developed by its researchers. Kyoto iCAP specializes in various sectors, including healthcare, medical devices, biotechnology, drug discovery, internet of things, artificial intelligence, machinery, clean technology, energy, new materials, food, and agriculture. The firm aims to bridge the gap between academic research and marketable innovations, fostering the growth of spin-off companies that leverage the university's intellectual assets.

Ko Kusumi

President and CEO

Tsuyoshi Tsujimura

Investment Manager

82 past transactions

RegCell

Seed Round in 2025
RegCell is focused on developing innovative therapies for autoimmune diseases and cancer by enhancing or regulating the immune system. The company specializes in creating cell therapies that aim to address significant unmet medical needs. By returning regulatory T cells to the patient and activating them in vitro, RegCell seeks to provide effective treatment options for individuals suffering from these challenging conditions. Through its novel approach, the company aims to improve patient outcomes and address the complexities associated with autoimmune disorders and cancer.

JiMED

Series A in 2025
JiMED is a company specializing in wireless embedded brain-computer interface (BCI) systems that monitor brain activity. It offers a wireless implantable BCI system that utilizes an implanted device in conjunction with artificial intelligence to interpret brain signals. This innovative technology allows individuals with ALS to control the device through thought, significantly enhancing their ability to communicate and improve their quality of life.

Holo Bio

Seed Round in 2025
Holo Bio is a research and technology firm dedicated to developing biological breeding techniques to tackle global food challenges. The company has created an innovative organism breeding technology that enhances the productivity of the intestinal bacterium GI35, which was discovered in the fish species native to Lake Biwa, Isaza. This bacterium is capable of supplying eicosapentaenoic acid (EPA) from fish, and Holo Bio's work enables the transformation of previously inedible plant fibers into edible forms. Through these advancements, Holo Bio aims to contribute to sustainable food solutions for society.

Enu Pharma

Seed Round in 2024
Enu Pharma is a pharmaceutical company focused on innovative research and the development of advanced medicines aimed at improving global healthcare standards. The company has developed a proprietary nanosome technology designed to assist healthcare professionals in effectively treating challenging diseases. This technology features core metals enveloped in an antiadhesive mixed self-assembled monolayer, which helps prevent non-specific surface protein interactions. By enhancing drug discovery, development, and delivery, Enu Pharma seeks to unlock new therapeutic possibilities and address unmet medical needs.

Koala Tech

Series B in 2024
Koala Tech Inc., founded in 2019 and based in Fukuoka, Japan, is a high-tech startup focused on developing organic semiconductor laser diodes. The company aims to pioneer practical applications of this innovative technology, which was first realized at the Center for Organic Photonics and Electronics Research at Kyushu University. Koala Tech's organic fluorescent semiconductor technology is notable for its ease of processing into thin films, making it less harmful and more efficient. This advancement provides businesses with a low-cost light source that can be seamlessly integrated into OLED and other organic electronic platforms, positioning Koala Tech at the forefront of the organic semiconductor industry.

Rhinoflux

Seed Round in 2024
Rhinoflux is an energy management company specializing in advanced thermal management technologies for efficient cooling systems.

OOYOO

Seed Round in 2024
OOYOO is a technology company specializing in the research and development of advanced gas separation membranes. Their primary focus is on carbon dioxide and hydrogen separation, aiming to create cleaner and more efficient air and gas purification solutions. The company's innovative, compact, and portable systems are designed to help industries reduce operational costs and promote sustainability, catering to sectors involved in environmental preservation and clean energy initiatives.

Rege Nephro

Series B in 2024
Rege Nephro Co., Ltd., established in 2019 and based in Kyoto, Japan, is a biotech company focused on the research, development, production, and marketing of therapeutics for renal diseases. The company leverages induced pluripotent stem cell (iPSC) technology, sourced from the Center for iPS Cell Research and Application at Kyoto University, to create innovative treatments for kidney, liver, and pancreas conditions. Rege Nephro develops drugs that utilize core seeds technology, which includes pluripotent stem cells capable of producing erythropoietin (EPO) and specific nephron progenitor cell markers. This approach aims to minimize the reliance on dialysis among patients with renal failure by offering effective therapeutic alternatives. Additionally, the company produces kidney organoids designed for nephrotoxicity screening, facilitating drug discovery in applied research.

RadioNano Therapeutics

Series A in 2024
RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Symbiobe

Series A in 2024
Symbiobe is a company that focuses on developing a resource-recycling material production platform aimed at promoting sustainability. By utilizing underexploited natural biomass resources and photosynthetic organisms, the platform offers innovative solutions for greenhouse gas fixation and the production of industrial biopolymers, nitrogen fertilizers, and aquaculture feed. This approach not only enhances the effectiveness of these materials but also supports environmental start-up businesses in obtaining natural and sustainable products. Symbiobe's mission is to advance manufacturing practices globally to ensure a sustainable future for generations to come.

EneCoat

Series C in 2024
EneCoat Technologies, established in 2018 and headquartered in Kyoto, Japan, specializes in the manufacturing and sale of perovskite solar cells and associated materials. The company focuses on developing and commercializing thin-film solar cell modules, aiming to harness solar energy efficiently, even in low-light conditions. EneCoat's mission is to protect the environment and optimize the use of natural energy sources, enabling businesses to generate power from solar cells conveniently.

Grand Green

Series C in 2024
Grand Green, established in 2017 and headquartered in Nagoya, Japan, specializes in the production of new seeds and seedlings through automatic grafting techniques. As a research and development agribio venture, the company focuses on innovative approaches to enhance agricultural practices and improve crop yield. By leveraging advanced technology in seedling production, Grand Green aims to contribute to the agricultural sector's growth and sustainability.

RadioNano Therapeutics

Seed Round in 2024
RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Restore Vision

Series A in 2023
Restore Vision is a biotechnology company focused on developing innovative therapies for eye diseases, particularly retinitis pigmentosa. The company specializes in gene therapy, utilizing advanced technology to create therapeutic agents that address intractable eye conditions. Restore Vision's approach involves the use of chimeric rhodopsin genes, which enhance the functionality of conventional rhodopsins, allowing for increased sensitivity in patients. This technology aims to improve treatment outcomes for individuals suffering from various eye disorders, providing new hope for visual restoration.

Melody International

Venture Round in 2023
Melody International is a manufacturing company that specializes in medical equipment designed for remote medical services. The company has developed an advanced fetal monitoring device that assists healthcare professionals during challenging delivery situations. This device includes a fetal heart monitor, a uterine contraction monitor, and a tablet interface. It features a built-in speaker connected to the transducer via the internet, allowing it to function as a fetal Doppler for monitoring pregnancy. This innovation enables women to assess maternal and fetal health conditions even from distant locations, thereby improving access to essential medical care.

QSimulate

Venture Round in 2023
QSimulate is a Boston-based company that develops cloud-based quantitative simulation tools aimed at addressing complex challenges in the chemical and pharmaceutical industries. By harnessing the principles of quantum mechanics, QSimulate’s platform facilitates quantum molecular simulations, allowing clients to tackle industrial-scale problems more effectively. The tools offered by the company automate workflows, relieving computational scientists of routine tasks and thereby increasing productivity. This innovation enables organizations to accelerate their research and development processes, ultimately enhancing their capacity to innovate and solve critical issues in their fields.

Sunlit Seedlings

Seed Round in 2022
Sunlit Seedlings is a consulting firm that specializes in the diagnosis and analysis of biological communities and ecosystems. The company provides a range of services that integrate various scientific fields, including ecology, mycology, and network science. By focusing on sustainable practices, Sunlit Seedlings aims to enhance food supply systems and contribute to the stabilization of the global environment. Additionally, the firm emphasizes the importance of soil ecosystems in agricultural land, helping communities understand their ecological value and promoting sustainable agricultural practices.

Symbiobe

Seed Round in 2022
Symbiobe is a company that focuses on developing a resource-recycling material production platform aimed at promoting sustainability. By utilizing underexploited natural biomass resources and photosynthetic organisms, the platform offers innovative solutions for greenhouse gas fixation and the production of industrial biopolymers, nitrogen fertilizers, and aquaculture feed. This approach not only enhances the effectiveness of these materials but also supports environmental start-up businesses in obtaining natural and sustainable products. Symbiobe's mission is to advance manufacturing practices globally to ensure a sustainable future for generations to come.

Toregem Biopharma

Venture Round in 2022
Toregem BioPharma, a startup originating from Kyoto University, is focused on developing therapeutic agents aimed at dental regeneration. Headquartered in Kyoto, Japan, the company specializes in treatments for congenital adentia and other dental issues. Its primary product is a tooth regeneration therapeutic agent that utilizes patients' own tissues to regenerate lost teeth. This innovative approach aims to provide solutions for individuals who have lost teeth due to decay or periodontal disease, ultimately promoting better oral health and improving quality of life.

Viage Therapeutics

Seed Round in 2022
Viage Therapeutics is a neuroscience company established in 2018, focused on developing innovative neurotherapeutics. The company aims to address psychiatric and inflammatory diseases by discovering and creating a new class of drugs targeting conditions such as depression, anxiety, and gastrointestinal disorders. Through its groundbreaking research, Viage Therapeutics seeks to provide researchers and healthcare professionals with access to novel treatments for significant unmet medical needs in these areas.

Rege Nephro

Venture Round in 2022
Rege Nephro Co., Ltd., established in 2019 and based in Kyoto, Japan, is a biotech company focused on the research, development, production, and marketing of therapeutics for renal diseases. The company leverages induced pluripotent stem cell (iPSC) technology, sourced from the Center for iPS Cell Research and Application at Kyoto University, to create innovative treatments for kidney, liver, and pancreas conditions. Rege Nephro develops drugs that utilize core seeds technology, which includes pluripotent stem cells capable of producing erythropoietin (EPO) and specific nephron progenitor cell markers. This approach aims to minimize the reliance on dialysis among patients with renal failure by offering effective therapeutic alternatives. Additionally, the company produces kidney organoids designed for nephrotoxicity screening, facilitating drug discovery in applied research.

BTB Drug Development Research Center

Seed Round in 2021
BTB Drug Discovery Research Center aims to contribute to reducing illness and saving lives. They create the product concept (TPP) and develop the finest plans possible for R&D, intellectual property, and pharmaceutical affairs. The company is developing a therapeutic medicine using a unique mechanism of action that encourages the release of endogenous opioids.

Myoridge

Venture Round in 2021
Myoridge Co. Ltd. is a biotechnology company based in Kyoto, Japan, that focuses on developing innovative solutions for cell differentiation and drug research. Established in 2016, the company specializes in a suspension culture system that facilitates the scalable differentiation of pluripotent cells into cardiomyocytes without the need for proteins, utilizing a novel small-molecule compound. Myoridge produces iPS cell-derived cardiomyocytes and cardiomyocyte fibers, which are characterized by high maturity and purity, offering excellent drug response rates. Their products also include software for analyzing myocardial motion and fluorescence. By employing a protein-free medium for cell culture, Myoridge achieves low production costs and lot-to-lot uniformity while closely approximating the characteristics of mature human cardiomyocytes. This approach supports advancements in regenerative medicine and drug development technologies.

Melody International

Venture Round in 2021
Melody International is a manufacturing company that specializes in medical equipment designed for remote medical services. The company has developed an advanced fetal monitoring device that assists healthcare professionals during challenging delivery situations. This device includes a fetal heart monitor, a uterine contraction monitor, and a tablet interface. It features a built-in speaker connected to the transducer via the internet, allowing it to function as a fetal Doppler for monitoring pregnancy. This innovation enables women to assess maternal and fetal health conditions even from distant locations, thereby improving access to essential medical care.

Cuorips

Venture Round in 2020
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, the company focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. Cuorips is involved in the manufacturing and sales of cellular and tissue-based products, as well as providing contract development and manufacturing services. The company aims to advance medical treatments through innovative cell products and therapies.

Perseus Proteomics

Venture Round in 2020
Perseus Proteomics Inc. is a biotechnology company based in Tokyo, Japan, focused on drug discovery and advanced antibody technology. Founded in 2001, the company specializes in antibody discovery, engineering, and target discovery, along with functional protein expression. Its services include mouse hybridoma sequencing, recombinant protein production, and contract research support for antibody development. Perseus Proteomics is dedicated to creating innovative antibody products and new medicines to improve healthcare outcomes for patients globally.

Kyoto Fusioneering

Seed Round in 2020
Kyoto Fusioneering is a privately funded technology start-up established in 2019 and based in Kyoto, Japan. The company specializes in developing advanced technologies for commercial fusion reactors, including gyrotron systems, tritium fuel cycle technologies, and breeding blankets for tritium production and power generation. By providing innovative solutions such as liquid metal and molten salt systems, as well as tritium treatment and high-frequency microwave gyrotrons, Kyoto Fusioneering aims to support both public and private fusion developers globally. The company's efforts contribute to the acceleration of fusion energy as a sustainable and carbon-free power source for the future.

ACT Genomics

Venture Round in 2020
ACT Genomics is a cancer molecular information service company that specializes in transforming cancer genomic information into precision diagnostics and personalized treatment strategies. With a team of experts experienced in oncology, cancer genomics, and bioinformatics, the company utilizes next-generation sequencing and multiplex molecular testing to provide comprehensive tumor profiling. This approach enables oncologists to identify specific genetic alterations that drive tumor development and influence treatment responses. By leveraging advanced bioinformatics tools and curated proprietary databases, ACT Genomics aims to enhance the effectiveness of cancer treatments and improve patient outcomes. The company’s services reflect a growing trend in oncology, where understanding the unique molecular characteristics of a patient's cancer is essential for developing tailored treatment plans.

Toregem Biopharma

Seed Round in 2020
Toregem BioPharma, a startup originating from Kyoto University, is focused on developing therapeutic agents aimed at dental regeneration. Headquartered in Kyoto, Japan, the company specializes in treatments for congenital adentia and other dental issues. Its primary product is a tooth regeneration therapeutic agent that utilizes patients' own tissues to regenerate lost teeth. This innovative approach aims to provide solutions for individuals who have lost teeth due to decay or periodontal disease, ultimately promoting better oral health and improving quality of life.

FLOSFIA

Venture Round in 2020
FLOSFIA INC. is a Tokyo-based company that specializes in developing corundum structured Gallium Oxide semiconductor power devices. Founded on March 31, 2011, as a spin-off from research at Kyoto University, the company focuses on film formation through mist chemical vapor deposition. FLOSFIA's products are characterized by high breakdown voltage and efficiency, aimed at creating low-loss power devices that leverage the advantageous properties of gallium oxide (Ga2O3).

U-Map

Venture Round in 2020
U-MaP Co., Ltd., established in 2016 and headquartered in Nagoya, Japan, specializes in the manufacturing of Aluminum Nitride (AlN) whiskers. These products excel in heat dissipation and thermal management, while also offering moldability. U-MaP's mission is to provide innovative solutions to society by commercializing advanced materials and processing technologies, with a focus on aluminum-based conductive materials that enhance end-product quality and sustainability. The company was spun off from Nagoya University and is primarily led by its researchers.

Rege Nephro

Series A in 2020
Rege Nephro Co., Ltd., established in 2019 and based in Kyoto, Japan, is a biotech company focused on the research, development, production, and marketing of therapeutics for renal diseases. The company leverages induced pluripotent stem cell (iPSC) technology, sourced from the Center for iPS Cell Research and Application at Kyoto University, to create innovative treatments for kidney, liver, and pancreas conditions. Rege Nephro develops drugs that utilize core seeds technology, which includes pluripotent stem cells capable of producing erythropoietin (EPO) and specific nephron progenitor cell markers. This approach aims to minimize the reliance on dialysis among patients with renal failure by offering effective therapeutic alternatives. Additionally, the company produces kidney organoids designed for nephrotoxicity screening, facilitating drug discovery in applied research.

Fimecs

Series A in 2020
Fimecs is a biotechnology firm specializing in drug discovery through protein degradation technology. The company focuses on developing innovative therapeutics aimed at treating cancers and other challenging diseases. Fimecs utilizes a drug discovery platform that operates on a ubiquitin E3 ligase binder, which facilitates the design of small molecules that induce the degradation of specific, disease-related proteins. While the human body contains over 18,000 proteins, approximately 1,500 are linked to various diseases, yet only around 300 have been identified as viable targets for small molecule drug interventions. Fimecs aims to expand the possibilities of druggable targets by addressing these previously undruggable proteins, ultimately seeking to enhance treatment options for patients.

EneCoat

Venture Round in 2020
EneCoat Technologies, established in 2018 and headquartered in Kyoto, Japan, specializes in the manufacturing and sale of perovskite solar cells and associated materials. The company focuses on developing and commercializing thin-film solar cell modules, aiming to harness solar energy efficiently, even in low-light conditions. EneCoat's mission is to protect the environment and optimize the use of natural energy sources, enabling businesses to generate power from solar cells conveniently.

Tiem Factory

Venture Round in 2020
Tiem Factory Inc. is a Tokyo-based company that specializes in the research, development, manufacturing, and sale of aerogel products under the brand name SUFA. Founded in 2012, Tiem Factory focuses on producing ultra-light transparent insulation materials designed for thermal insulation applications. Notably, the company has developed a unique method for creating its insulation materials without utilizing supercritical drying processes, allowing clients to obtain insulation composed primarily of air. This innovative approach positions Tiem Factory as a leader in the field of advanced insulation solutions.

LegalForce

Series B in 2020
LegalForce, Inc., founded in 2017 and headquartered in Toyosu, Tokyo, Japan, specializes in developing and maintaining AI-powered software for legal services, particularly in contract management. The platform employs natural language processing and other advanced technologies to assist legal professionals by reviewing contracts based on their type, identifying potentially omitted or risky clauses, and minimizing oversights. This functionality aims to enhance the quality and efficiency of legal operations, providing valuable support in the contract review process.

LegalOn Technologies

Series B in 2020
LegalOn Technologies is a global leader in AI contract review, assisting over 5,000 companies and law firms in enhancing their contract negotiation processes by making them faster and more accurate. Founded in 2017, the company leverages artificial intelligence combined with the expertise of experienced attorneys to identify risks within contracts and support various contract-related operations. LegalOn's platform enables legal and business teams to save time, reduce legal risks, and escape tedious tasks, allowing them to focus on more strategic aspects of their work. The software offers customizable playbooks, streamlines contract search and storage, and provides an AI assistant for real-time contract inquiries, both online and integrated within Microsoft Word. With significant backing from prominent investors, LegalOn operates on a global scale, particularly in the US and Japan, delivering immediate value to its users through its comprehensive AI contract review solution.

Kyoto Fusioneering

Seed Round in 2020
Kyoto Fusioneering is a privately funded technology start-up established in 2019 and based in Kyoto, Japan. The company specializes in developing advanced technologies for commercial fusion reactors, including gyrotron systems, tritium fuel cycle technologies, and breeding blankets for tritium production and power generation. By providing innovative solutions such as liquid metal and molten salt systems, as well as tritium treatment and high-frequency microwave gyrotrons, Kyoto Fusioneering aims to support both public and private fusion developers globally. The company's efforts contribute to the acceleration of fusion energy as a sustainable and carbon-free power source for the future.

Myoridge

Seed Round in 2020
Myoridge Co. Ltd. is a biotechnology company based in Kyoto, Japan, that focuses on developing innovative solutions for cell differentiation and drug research. Established in 2016, the company specializes in a suspension culture system that facilitates the scalable differentiation of pluripotent cells into cardiomyocytes without the need for proteins, utilizing a novel small-molecule compound. Myoridge produces iPS cell-derived cardiomyocytes and cardiomyocyte fibers, which are characterized by high maturity and purity, offering excellent drug response rates. Their products also include software for analyzing myocardial motion and fluorescence. By employing a protein-free medium for cell culture, Myoridge achieves low production costs and lot-to-lot uniformity while closely approximating the characteristics of mature human cardiomyocytes. This approach supports advancements in regenerative medicine and drug development technologies.

Luxonus

Series A in 2019
Luxonus is a medical device manufacturing company specializing in photoacoustic technology aimed at early disease detection and diagnosis. The company has developed an advanced imaging device that utilizes optical ultrasonic technology, which combines light and ultrasonic waves to create ultra-high-resolution three-dimensional images of blood vessels and lymphatic vessels. This innovative approach allows for safe and easy imaging without exposure, providing healthcare professionals with a comprehensive understanding of disease onset, healing processes, and overall health conditions before and after illness.

Thyas

Venture Round in 2019
Thyas Co. Ltd. specializes in regenerative immunocell therapy aimed at treating cancer and infectious diseases. The company has developed a method for creating regenerative T cells from human induced pluripotent stem (iPS) cells. By offering personalized regenerative immuno-cell therapy, Thyas focuses on enhancing treatment options for patients battling cancer and various infections. Through its innovative approach, the company seeks to improve patient outcomes and contribute to advancements in cancer treatment and immunology.

Algal Bio

Venture Round in 2019
Algal Bio Co., Ltd., established in 2018 and based in Kashiwa, Japan, specializes in the research, development, production, and sale of algae and its components. Drawing on two decades of research from the University of Tokyo, the company focuses on producing rare fatty acids and carotenoids while also engaging in food processing, importing, exporting, and distributing algae and its ingredients. Algal Bio operates a laboratory dedicated to exploring the functionality of microalgae as food ingredients, employing a unique algae bio-foundry platform that integrates various screening and cultivation technologies. The company aims to address significant global challenges, including rising health consciousness, food shortages, and climate change, by applying algae across diverse industries and applications.

aceRNA Technologies

Series A in 2019
aceRNA Technologies is a biotechnology startup focused on developing innovative genetic therapies utilizing RNA switch technology. The company specializes in regenerative medicine, aiming to discover novel functions of microRNAs (miRNAs) that can regulate gene expression. By harnessing this technology, aceRNA Technologies seeks to facilitate the removal of undifferentiated and potentially cancerous cells, thereby enhancing drug discovery and therapeutic applications. Through its patient-centric approach, the company strives to advance the field of genetic therapies and improve treatment outcomes in various medical conditions.

Thyas

Venture Round in 2019
Thyas Co. Ltd. specializes in regenerative immunocell therapy aimed at treating cancer and infectious diseases. The company has developed a method for creating regenerative T cells from human induced pluripotent stem (iPS) cells. By offering personalized regenerative immuno-cell therapy, Thyas focuses on enhancing treatment options for patients battling cancer and various infections. Through its innovative approach, the company seeks to improve patient outcomes and contribute to advancements in cancer treatment and immunology.

Space Power Technologies

Venture Round in 2019
Space Power Technologies is a Japanese company founded in 2019 that focuses on the development and manufacturing of microwave-based wireless power transmission systems. As a pioneer in spatial transmission wireless power technology, the company aims to address social issues related to power supply by integrating advanced academic technologies with practical applications. Its innovative systems are designed for various scenarios, including industrial environments, logistics sites, infrastructure monitoring, remote areas lacking power infrastructure, disaster recovery zones, and even outer space. By enabling wireless power transfer at a distance using radio waves, Space Power Technologies aspires to contribute to the creation of a more connected and efficient society.

Kyulux

Series B in 2019
Kyulux, Inc. is a Japanese company specializing in the research and development of organic electroluminescent materials for organic light-emitting diode (OLED) displays and lighting solutions. Founded in 2015 and based in Fukuoka, Kyulux is a leader in the advancement of thermally activated delayed fluorescence (TADF) technology, which enhances the efficiency of OLED emission. The company offers innovative products, including its proprietary Hyperfluorescence solution, which combines TADF and fluorescence emitters. This technology enables manufacturers in the display and lighting industries to produce cost-effective, durable, and efficient OLED solutions without relying on rare metals. With a significant intellectual property portfolio developed at Kyushu University and in collaboration with industrial partners, Kyulux is positioned at the forefront of the OLED technology market.

On The Slope

Venture Round in 2019
On the way to Sakano deliver vegetables grown without the use of pesticides and chemical fertilizers, aiming to spread agriculture with low environmental impact. We want to make agriculture sustainable and reach a sustainable society.

Sho Engineering

Seed Round in 2019
Sho Engineering is a company that specializes in planning, research, and product development within the field of wireless transmission equipment. It aims to enhance safety and comfort in society through innovative technology. The company's products include a data transmitter powered by wireless energy, which facilitates the transmission of data, wireless power, and data transfer through devices designed for long-distance identity card services. Additionally, Sho Engineering has developed an emergency and volcano observation monitoring assistance system, providing clients with advanced solutions to enhance safety and security in various scenarios.

AlphaNavi Pharma

Series A in 2019
AlphaNavi Pharma Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. It focuses on drug discovery and the development of innovative pain therapeutics, specifically targeting peripheral neuropathic pain through its products ANP-230 and ANP-231, which are voltage-gated sodium channel selective inhibitors. The company is committed to advancing research and clinical development by collaborating with academia, investors, and healthcare professionals. Through these partnerships, AlphaNavi Pharma aims to create new value in the field of pain management, ultimately helping to alleviate suffering and improve the quality of life for patients and their families.

Chordia Therapeutics

Series B in 2019
Chordia Therapeutics Inc. is a clinical-stage biotechnology company based in Fujisawa, Japan, founded in 2017. The company focuses on the research and development of innovative oncology drugs aimed at addressing significant unmet medical needs in cancer treatment. Chordia Therapeutics is dedicated to delivering first-in-class therapeutic options to patients, emphasizing the importance of advancing cancer care through its specialized bioventure efforts.

Luxonus

Venture Round in 2019
Luxonus is a medical device manufacturing company specializing in photoacoustic technology aimed at early disease detection and diagnosis. The company has developed an advanced imaging device that utilizes optical ultrasonic technology, which combines light and ultrasonic waves to create ultra-high-resolution three-dimensional images of blood vessels and lymphatic vessels. This innovative approach allows for safe and easy imaging without exposure, providing healthcare professionals with a comprehensive understanding of disease onset, healing processes, and overall health conditions before and after illness.

SOUSEI Technology

Venture Round in 2019
SOUSEI Technology, Inc. specializes in developing software and hardware solutions for home design and management. Founded in 2018 and based in Tokyo, Japan, the company offers an Internet of Things (IoT) device called v-ex, which enables homeowners to communicate with their home electronics through voice commands. Additionally, SOUSEI Technology provides an online platform named Knot, designed to facilitate connections between housing companies and homeowners. This platform allows housing companies to efficiently manage customer and property information, as well as documentation related to security and compliance. The company's focus on user experience design and artificial intelligence supports its mission to enhance management and product development in the housing sector.

LegalOn Technologies

Series A in 2019
LegalOn Technologies is a global leader in AI contract review, assisting over 5,000 companies and law firms in enhancing their contract negotiation processes by making them faster and more accurate. Founded in 2017, the company leverages artificial intelligence combined with the expertise of experienced attorneys to identify risks within contracts and support various contract-related operations. LegalOn's platform enables legal and business teams to save time, reduce legal risks, and escape tedious tasks, allowing them to focus on more strategic aspects of their work. The software offers customizable playbooks, streamlines contract search and storage, and provides an AI assistant for real-time contract inquiries, both online and integrated within Microsoft Word. With significant backing from prominent investors, LegalOn operates on a global scale, particularly in the US and Japan, delivering immediate value to its users through its comprehensive AI contract review solution.

EneCoat

Venture Round in 2019
EneCoat Technologies, established in 2018 and headquartered in Kyoto, Japan, specializes in the manufacturing and sale of perovskite solar cells and associated materials. The company focuses on developing and commercializing thin-film solar cell modules, aiming to harness solar energy efficiently, even in low-light conditions. EneCoat's mission is to protect the environment and optimize the use of natural energy sources, enabling businesses to generate power from solar cells conveniently.

LegalForce

Seed Round in 2018
LegalForce, Inc., founded in 2017 and headquartered in Toyosu, Tokyo, Japan, specializes in developing and maintaining AI-powered software for legal services, particularly in contract management. The platform employs natural language processing and other advanced technologies to assist legal professionals by reviewing contracts based on their type, identifying potentially omitted or risky clauses, and minimizing oversights. This functionality aims to enhance the quality and efficiency of legal operations, providing valuable support in the contract review process.

Mitsucari

Series B in 2018
Mitsucari is an HR technology service company that specializes in optimizing organizational dynamics through an in-depth analysis of individual personality traits and compatibility. It has developed a candidate verification platform that matches job seekers' personalities and values with the corporate culture of potential employers. This platform employs aptitude tests for job seekers while simultaneously assessing current employees to gauge the corporate environment. By identifying personality alignments and preferred working conditions, Mitsucari aims to enhance job matching, facilitating better employment outcomes for candidates and promoting employee retention for organizations.

aceRNA Technologies

Seed Round in 2018
aceRNA Technologies is a biotechnology startup focused on developing innovative genetic therapies utilizing RNA switch technology. The company specializes in regenerative medicine, aiming to discover novel functions of microRNAs (miRNAs) that can regulate gene expression. By harnessing this technology, aceRNA Technologies seeks to facilitate the removal of undifferentiated and potentially cancerous cells, thereby enhancing drug discovery and therapeutic applications. Through its patient-centric approach, the company strives to advance the field of genetic therapies and improve treatment outcomes in various medical conditions.

Connexx Systems

Venture Round in 2018
Connexx Systems, established in 2011 and headquartered in Kyoto, Japan, specializes in the development and integration of power storage systems. The company focuses on core battery technologies, creating household and mobile storage solutions for emergency use. Connexx Systems sells its products through distributors and catalogs, with additional offices in Tokyo and Fukuoka, Japan.

Cuorips

Venture Round in 2018
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, the company focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. Cuorips is involved in the manufacturing and sales of cellular and tissue-based products, as well as providing contract development and manufacturing services. The company aims to advance medical treatments through innovative cell products and therapies.

Sho Engineering

Seed Round in 2018
Sho Engineering is a company that specializes in planning, research, and product development within the field of wireless transmission equipment. It aims to enhance safety and comfort in society through innovative technology. The company's products include a data transmitter powered by wireless energy, which facilitates the transmission of data, wireless power, and data transfer through devices designed for long-distance identity card services. Additionally, Sho Engineering has developed an emergency and volcano observation monitoring assistance system, providing clients with advanced solutions to enhance safety and security in various scenarios.

LegalForce

Seed Round in 2018
LegalForce, Inc., founded in 2017 and headquartered in Toyosu, Tokyo, Japan, specializes in developing and maintaining AI-powered software for legal services, particularly in contract management. The platform employs natural language processing and other advanced technologies to assist legal professionals by reviewing contracts based on their type, identifying potentially omitted or risky clauses, and minimizing oversights. This functionality aims to enhance the quality and efficiency of legal operations, providing valuable support in the contract review process.

LegalOn Technologies

Seed Round in 2018
LegalOn Technologies is a global leader in AI contract review, assisting over 5,000 companies and law firms in enhancing their contract negotiation processes by making them faster and more accurate. Founded in 2017, the company leverages artificial intelligence combined with the expertise of experienced attorneys to identify risks within contracts and support various contract-related operations. LegalOn's platform enables legal and business teams to save time, reduce legal risks, and escape tedious tasks, allowing them to focus on more strategic aspects of their work. The software offers customizable playbooks, streamlines contract search and storage, and provides an AI assistant for real-time contract inquiries, both online and integrated within Microsoft Word. With significant backing from prominent investors, LegalOn operates on a global scale, particularly in the US and Japan, delivering immediate value to its users through its comprehensive AI contract review solution.

AFI

Series B in 2018
AFI, established in Seoul, South Korea in 2013, is a technology company focused on food safety and quality. It manufactures and sells innovative products, including an electric filter separation technology and a rapid detection system for microbial contamination, serving the food and life science industries. AFI's solutions enable clients to monitor and enhance food safety, responding to diverse client needs such as rapid microbiological testing.

Questetra

Venture Round in 2017
Questetra, Inc. is an enterprise cloud computing company based in Kyoto, Japan, established in 2008. It specializes in providing business process management (BPM) tools designed to enhance productivity and optimize workflows for various organizations. The Questetra BPM Suite enables users to develop BPMN-driven workflows through a user-friendly, web-based interface, allowing for both process design and task execution directly in a browser. The platform supports various business processes, such as estimating, invoice issuing, and inquiry responses, and offers integration with Google Apps for seamless user access and data export to Google Docs. Additionally, Questetra provides BPM consulting services to further assist organizations in improving their operational efficiency.

Chordia Therapeutics

Series A in 2017
Chordia Therapeutics Inc. is a clinical-stage biotechnology company based in Fujisawa, Japan, founded in 2017. The company focuses on the research and development of innovative oncology drugs aimed at addressing significant unmet medical needs in cancer treatment. Chordia Therapeutics is dedicated to delivering first-in-class therapeutic options to patients, emphasizing the importance of advancing cancer care through its specialized bioventure efforts.

Thyas

Venture Round in 2017
Thyas Co. Ltd. specializes in regenerative immunocell therapy aimed at treating cancer and infectious diseases. The company has developed a method for creating regenerative T cells from human induced pluripotent stem (iPS) cells. By offering personalized regenerative immuno-cell therapy, Thyas focuses on enhancing treatment options for patients battling cancer and various infections. Through its innovative approach, the company seeks to improve patient outcomes and contribute to advancements in cancer treatment and immunology.

Stem Cell & Device Laboratory

Series B in 2017
Stem Cell & Device Laboratory, Inc. focuses on research and development, manufacturing, and sales of cellular products, devices, and integrated cell-material products specifically designed for drug discovery applications. The company specializes in creating innovative scaffold materials that enhance cell functionality and compatibility, leveraging advanced micro-engineering and nanofabrication technologies. Founded in 2014 and headquartered in Kyoto, Japan, Stem Cell & Device Laboratory is dedicated to advancing cell applications that contribute to a healthier society.

Oligogen

Venture Round in 2017
Oligogen is a bio-venture based in Kyoto, Japan, founded in 2015. The company focuses on drug development and regenerative medicine, specifically utilizing neural stem cell technologies to create therapies for patients with central nervous system diseases. Oligogen aims to treat conditions such as spinal cord injuries and other neurological disorders, including congenital leukoplakia and multiple sclerosis. By harnessing the potential of human neural stem cells, Oligogen seeks to provide effective cell therapies that enhance neurological healthcare for affected individuals.

Thyas

Venture Round in 2017
Thyas Co. Ltd. specializes in regenerative immunocell therapy aimed at treating cancer and infectious diseases. The company has developed a method for creating regenerative T cells from human induced pluripotent stem (iPS) cells. By offering personalized regenerative immuno-cell therapy, Thyas focuses on enhancing treatment options for patients battling cancer and various infections. Through its innovative approach, the company seeks to improve patient outcomes and contribute to advancements in cancer treatment and immunology.

Connexx Systems

Venture Round in 2017
Connexx Systems, established in 2011 and headquartered in Kyoto, Japan, specializes in the development and integration of power storage systems. The company focuses on core battery technologies, creating household and mobile storage solutions for emergency use. Connexx Systems sells its products through distributors and catalogs, with additional offices in Tokyo and Fukuoka, Japan.

NS Materials

Venture Round in 2017
NS Materials Corp. is a manufacturer and distributor of semiconductor-related equipment and systems based in Chikushino-shi, Japan. The company focuses on developing micro-space chemical technologies, particularly specializing in nano-phosphor for LED lighting and innovative chemical synthesis techniques. By advancing these technologies, NS Materials aims to establish a new field within nanotechnology and biotechnology. Their offerings are designed to provide clients with tools and products that contribute to a low-carbon society, significantly impacting daily life and promoting sustainability.

FLOSFIA

Venture Round in 2017
FLOSFIA INC. is a Tokyo-based company that specializes in developing corundum structured Gallium Oxide semiconductor power devices. Founded on March 31, 2011, as a spin-off from research at Kyoto University, the company focuses on film formation through mist chemical vapor deposition. FLOSFIA's products are characterized by high breakdown voltage and efficiency, aimed at creating low-loss power devices that leverage the advantageous properties of gallium oxide (Ga2O3).

Tiem Factory

Venture Round in 2017
Tiem Factory Inc. is a Tokyo-based company that specializes in the research, development, manufacturing, and sale of aerogel products under the brand name SUFA. Founded in 2012, Tiem Factory focuses on producing ultra-light transparent insulation materials designed for thermal insulation applications. Notably, the company has developed a unique method for creating its insulation materials without utilizing supercritical drying processes, allowing clients to obtain insulation composed primarily of air. This innovative approach positions Tiem Factory as a leader in the field of advanced insulation solutions.

Audio Metaverse

Corporate Round in 2017
Audio Metaverse, known as Cubemint, operates at the intersection of physical reality and virtual environments by creating immersive 3D audio spaces. This platform allows users to mint NFTs and explore these audio realms collectively, enhancing their interaction with both digital and physical assets. The company specializes in an audio streaming application designed to foster real-time conversations among friends and followers. By integrating augmented audio reality, Cubemint facilitates live streaming sessions that can last for several hours, enabling users to engage with one another through comments and discussions. This innovative approach allows individuals to experience and share their ideas authentically while navigating between physical spaces and their corresponding digital audio environments.

PrediXT

Seed Round in 2016
PrediXT is a developer of prediction technologies.

Mitsucari

Corporate Round in 2016
Mitsucari is an HR technology service company that specializes in optimizing organizational dynamics through an in-depth analysis of individual personality traits and compatibility. It has developed a candidate verification platform that matches job seekers' personalities and values with the corporate culture of potential employers. This platform employs aptitude tests for job seekers while simultaneously assessing current employees to gauge the corporate environment. By identifying personality alignments and preferred working conditions, Mitsucari aims to enhance job matching, facilitating better employment outcomes for candidates and promoting employee retention for organizations.

Lang-8

Venture Round in 2016
Lang-8, Inc. operates a language exchange social networking portal designed to enhance language learning through interaction with native speakers. Founded in 2007 and based in Tokyo, Japan, the platform allows users to write journal entries in the language they are learning. Native speakers then provide corrections and feedback, facilitating a collaborative learning environment. This mutual exchange not only aids learners in improving their writing skills but also enables them to assist others in their language journey. Lang-8 supports a wide range of over 70 languages and has attracted a global user base from 180 countries, fostering a friendly community focused on sharing knowledge and cultural understanding.

KinoPharma

Venture Round in 2016
KinoPharma, Inc. is a Tokyo-based company founded in 2005 that specializes in the discovery and development of small molecule drugs targeting serine/threonine kinases. The company engages in collaborative research and development through partnerships with universities, focusing on creating clinical drugs with minimal side effects. KinoPharma leverages its expertise in phosphoenzyme inhibitor research to develop therapeutic agents for challenging conditions, including viral and neurodegenerative diseases. One of its key initiatives involves the creation of next-generation antiviral drugs aimed at addressing papillomavirus (HPV) infections in women, specifically targeting the prevention of cervical cancer.

Kyoto Drug Discovery & Development

Venture Round in 2016
Kyoto Drug Discovery and Development Co. Ltd., based in Kyoto, Japan, specializes in the development of therapeutic drugs aimed at treating chronic degenerative eye diseases. The company focuses on innovative agents for conditions such as glaucoma, central retinal artery occlusion (CRAO), retinitis pigmentosa, and age-related macular degeneration (AMD), which are often considered incurable or intractable. By creating effective treatments for these serious conditions, Kyoto Drug Discovery and Development enables healthcare professionals to better diagnose and manage patients suffering from these debilitating eye diseases.

AFI

Series A in 2016
AFI, established in Seoul, South Korea in 2013, is a technology company focused on food safety and quality. It manufactures and sells innovative products, including an electric filter separation technology and a rapid detection system for microbial contamination, serving the food and life science industries. AFI's solutions enable clients to monitor and enhance food safety, responding to diverse client needs such as rapid microbiological testing.

Stem Cell & Device Laboratory

Series A in 2016
Stem Cell & Device Laboratory, Inc. focuses on research and development, manufacturing, and sales of cellular products, devices, and integrated cell-material products specifically designed for drug discovery applications. The company specializes in creating innovative scaffold materials that enhance cell functionality and compatibility, leveraging advanced micro-engineering and nanofabrication technologies. Founded in 2014 and headquartered in Kyoto, Japan, Stem Cell & Device Laboratory is dedicated to advancing cell applications that contribute to a healthier society.
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