.406 Ventures

Boston-based venture capital firm founded in 2005 that focuses on early-stage and select growth investments in information technology and related services. The firm backs enterprise IT companies, emphasizing information security, cloud infrastructure, data analytics, and software-as-a-service models, as well as technology-enabled business services and digital health, and it also targets healthcare IT, fintech, mobile software, and next-generation software. It prefers open source and SaaS delivery. Typically investing initial rounds of 2 to 5 million and totaling 6 to 10 million per company, it seeks board representation and often serves as lead or first institutional investor, with minority to majority stakes ranging from 20 to 80 percent. The firm reserves capital for opportunistic investments in more mature companies where its team has prior experience and focuses on opportunities in the Northeast United States.

Graham Brooks

Partner

Payal Agrawal Divakaran

Partner

Liam Donohue

Managing Partner

Greg Dracon

Partner

Austin Kwoun

Analyst

So-June Min

Managing Director of Operations

Kathryn Reddy

Principal

Rebecca Redfield

Associate

Past deals in Mental Health

Nema Health

Series A in 2024
Nema Health operates an online trauma care platform that delivers cognitive processing therapy and other PTSD treatments through a virtual care center. The service enables individuals with post-traumatic stress disorder and related stress disorders to receive therapy from home, administered by PTSD-trained therapists. The platform focuses on comprehensive, long-lasting relief through remote care, combining professional psychotherapy with convenient, privacy-conscious access to treatment.

InStride Health

Series B in 2024
InStride Health is an outpatient care platform focused on delivering evidence-based treatment for pediatric anxiety and obsessive-compulsive disorder (OCD). The company offers a tailored virtual care journey that includes individual and group therapy, coaching, and medication management. This comprehensive approach is facilitated by a coordinated team of experienced psychiatrists, therapists, and coaches, ensuring that children and teenagers receive effective and accessible care. InStride Health aims to engage young patients and their families in their treatment, making mental health support both affordable and effective.

FamilyWell

Seed Round in 2024
FamilyWell Health is a digital health company that integrates behavioral health services into obstetric practices. It offers a tech-enabled, collaborative care approach to address the maternal mental health crisis in the U.S., focusing on equitable and affordable access to mental health services for pregnant and postpartum patients. The company provides in-person and virtual care, including psychiatric consultations, licensed therapy, health coaching, and peer-to-peer text message support throughout the perinatal journey. It also guides providers on medication management, ensuring easy access to mental health care for patients.

Nema Health

Seed Round in 2023
Nema Health operates an online trauma care platform that delivers cognitive processing therapy and other PTSD treatments through a virtual care center. The service enables individuals with post-traumatic stress disorder and related stress disorders to receive therapy from home, administered by PTSD-trained therapists. The platform focuses on comprehensive, long-lasting relief through remote care, combining professional psychotherapy with convenient, privacy-conscious access to treatment.

Cortica

Series D in 2023
Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.

InStride Health

Venture Round in 2022
InStride Health is an outpatient care platform focused on delivering evidence-based treatment for pediatric anxiety and obsessive-compulsive disorder (OCD). The company offers a tailored virtual care journey that includes individual and group therapy, coaching, and medication management. This comprehensive approach is facilitated by a coordinated team of experienced psychiatrists, therapists, and coaches, ensuring that children and teenagers receive effective and accessible care. InStride Health aims to engage young patients and their families in their treatment, making mental health support both affordable and effective.

Equip Health

Series B in 2022
Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery. Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.

Cortica

Series C in 2021
Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.

Equip Health

Series A in 2021
Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery. Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.

Equip Health

Series A in 2021
Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery. Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.

Hurdle

Seed Round in 2021
Hurdle Health, Inc., established in 2020 and based in Washington, D.C., specializes in culturally intentional mental health services. The company operates a digital platform that connects diverse individuals, couples, and families with appropriate therapists, offering a suite of teletherapy services and self-mastery tools. Hurdle's approach is tailored to meet the unique needs of underserved populations, providing culturally responsive care for a wide range of stressors. The platform aims to create a safe and understanding space for patients, focusing on serving the BIPOC community and other minority groups.

AbleTo

Series D in 2017
AbleTo is a leading provider of virtual behavioral healthcare services in the United States. It uses an integrated proprietary platform to identify and engage individuals with unmet behavioral health needs, connecting them with licensed therapists/coaches nationwide. AbleTo's tele-behavioral health programs improve clinical outcomes for patients with conditions such as depression, anxiety, stress, heart disease, diabetes, and chronic pain.

Annum

Seed Round in 2016
Annum Health, Inc., established in 2016 and headquartered in New York, specializes in modern, tech-enabled rehabilitation services for individuals struggling with heavy drinking. The company, co-founded by experts in healthcare, technology, and alcohol treatment, provides a comprehensive, year-long program at a significantly lower cost than traditional inpatient rehab. This program combines therapy, coaching, medication, and online support to help individuals achieve their personal goals and overcome alcohol-related issues, while minimizing disruption to their personal and professional lives and reducing the stigma associated with treatment.

AbilTo

Series C in 2015
AbilTo is a national behavioral healthcare provider that offers telehealth services across all fifty states, focusing on individuals experiencing emotional and behavioral challenges due to medical events and life transitions. The company provides support through a network of licensed therapists and behavior coaches who guide participants in an eight-week program aimed at helping them set and achieve personal goals. This program is designed to assist individuals in reclaiming their lives, enhancing their overall happiness, health, and productivity. AbilTo operates under the brand name for various professional services entities that are either managed by or affiliated with AbilTo Inc.

AbilTo

Series B in 2014
AbilTo is a national behavioral healthcare provider that offers telehealth services across all fifty states, focusing on individuals experiencing emotional and behavioral challenges due to medical events and life transitions. The company provides support through a network of licensed therapists and behavior coaches who guide participants in an eight-week program aimed at helping them set and achieve personal goals. This program is designed to assist individuals in reclaiming their lives, enhancing their overall happiness, health, and productivity. AbilTo operates under the brand name for various professional services entities that are either managed by or affiliated with AbilTo Inc.

AbilTo

Series A in 2013
AbilTo is a national behavioral healthcare provider that offers telehealth services across all fifty states, focusing on individuals experiencing emotional and behavioral challenges due to medical events and life transitions. The company provides support through a network of licensed therapists and behavior coaches who guide participants in an eight-week program aimed at helping them set and achieve personal goals. This program is designed to assist individuals in reclaiming their lives, enhancing their overall happiness, health, and productivity. AbilTo operates under the brand name for various professional services entities that are either managed by or affiliated with AbilTo Inc.
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