Headwater Ventures

Headwater Ventures is a venture capital firm founded in 2021 and based in Minneapolis, Minnesota, focused on early-stage health technology investments. It backs technology solutions across health information technology, digital health, insurtech, fintech, artificial intelligence and machine learning, data analytics, and other tech-enabled health services.

Matt Miller

General Partner

26 past transactions

Affineon

Seed Round in 2025
Affineon is a healthcare technology company that specializes in AI-driven inbox management. It automates the processing of routine and clinically insignificant lab results, reducing the workload for healthcare providers. The platform groups, analyzes, and trends lab results into concise summaries, including potential next steps and complete patient notes. It also routes non-urgent messages to staff, decreasing the number of messages providers need to attend to by up to 30%. This results in significant time savings, with providers gaining over five hours per week. Affineon seamlessly integrates with existing electronic health records (EHR) systems, ensuring providers can continue using their current workflows.

Affineon

Seed Round in 2024
Affineon is a healthcare technology company that specializes in AI-driven inbox management. It automates the processing of routine and clinically insignificant lab results, reducing the workload for healthcare providers. The platform groups, analyzes, and trends lab results into concise summaries, including potential next steps and complete patient notes. It also routes non-urgent messages to staff, decreasing the number of messages providers need to attend to by up to 30%. This results in significant time savings, with providers gaining over five hours per week. Affineon seamlessly integrates with existing electronic health records (EHR) systems, ensuring providers can continue using their current workflows.

Ferrum Health

Series A in 2024
Ferrum Health, Inc. is a health technology company based in Santa Clara, California, that specializes in developing an artificial intelligence platform aimed at preventing medical errors and enhancing patient safety. Incorporated in 2017, Ferrum Health's AI-driven platform analyzes patient data across healthcare systems to identify opportunities for closing gaps in care. The platform features a comprehensive patient safety evaluation system, which includes multiple computer vision algorithms that assess radiologic images for commonly missed conditions, such as lung nodules and fractures. Additionally, it employs proprietary natural language processing algorithms to correlate findings with physician notes, effectively flagging potential oversights for hospital quality officers to address. By integrating AI, Ferrum Health strives to improve patient outcomes and support hospital systems in maintaining high standards of care.

Andy AI

Pre Seed Round in 2024
Andy AI is a technology company that specializes in AI-driven software for healthcare professionals. Its primary product is a clinical documentation platform designed specifically for nurses conducting home visits. This platform aims to enhance charting accuracy, increase productivity, and reduce clinician burnout by automating and streamlining documentation processes. By doing so, Andy AI enables clinicians to better connect with patients in home health settings.

Piction Health

Seed Round in 2024
Piction Health is a company focused on enhancing access to dermatology care for patients experiencing skin, hair, or nail issues. The company offers a dermatology care application that allows patients to receive expert consultations from dermatologists within two days, including a diagnosis and personalized care plan. By leveraging artificial intelligence, Piction Health streamlines the diagnostic process for both patients and primary care providers, enabling quicker assessments of complex skin conditions. The application provides immediate second opinions, allowing primary care providers to efficiently address challenging skin diseases, thereby saving time and reducing costs associated with unnecessary repeat visits and ineffective treatments. Piction Health aims to ensure that high-quality dermatological care is accessible from the comfort of home, ultimately improving patient outcomes.

Mirza

Venture Round in 2023
Mirza is a FinTech company that focuses on providing tax-efficient employer stipends to a network of caregivers. Its platform integrates family financial planning and childcare funding, helping organizations enhance their corporate policies related to parental leave, fertility options, and modern parenting advice. By offering these tools, Mirza enables working professionals to navigate their financial responsibilities while supporting their roles as caregivers. The company aims to empower employees by facilitating their financial goals through innovative solutions tailored to the needs of modern families.

Venteur

Seed Round in 2023
Venteur simplifies employee health benefits through its AI-driven platform. It facilitates Individual Coverage Health Reimbursement Arrangements (ICHRAs), empowering employees with tailored insurance options while providing employers predictability in benefits budget and cost control.

Elion

Seed Round in 2022
Elion operates a digital health software marketplace that connects healthcare providers with relevant vendors. Its platform facilitates informed decision-making through comprehensive vendor listings, product evaluations, and educational resources.

Reema Health

Seed Round in 2022
Reema Health is a technology startup focused on bridging the gaps between healthcare and social care. The company operates a healthcare platform that utilizes tech-enabled community guides to connect individuals with essential care and resources. By offering a personalized, community-based approach, Reema Health empowers users to identify specific actions needed to improve their behavioral health. This innovative platform aims to facilitate easier access to medical care and enhance the overall well-being of its users.

Koda Health

Seed Round in 2022
Koda Health develops an AI-driven video-based platform that guides elderly patients through personalized end-of-life conversations, empowering them to make informed healthcare decisions and ensuring their preferences are respected. This reduces inappropriate care and generates valuable data on patient personas while saving costs for healthcare systems.

Credo

Seed Round in 2022
Credo provides instant access to medical records for providers, payers and patients. Patients, providers, and medicine have all evolved over the years, yet somehow fax machines are still the primary method of transferring health records today. Credo is here to change that.

Kiddo Health

Series A in 2022
Kiddo Health offers a connected care platform focused on managing chronic health conditions in school-aged children and adolescents. The platform captures health data and provides insights to support healthcare providers and parents in addressing the comprehensive needs of each child.

Pair Team

Seed Round in 2021
Pair Team provides healthcare coordination services focused on underserved and vulnerable communities. It deploys a dedicated, tech-enabled care team—including community health workers, registered nurses, and behavioral health clinicians—to offer personalized, holistic support to Medicaid and Medicare patients and other low-income individuals facing barriers to care such as transportation, housing and food insecurity, and limited mobile access. The company acts as an extension of safety-net primary care systems, helping them deliver patient-centered care while integrating with community-based organizations. It is building a care delivery platform to standardize clinical practices, streamline administrative tasks, and enable clinicians to spend more time with patients.

Suggestic

Venture Round in 2021
Suggestic, Inc. is a San Francisco-based company founded in 2014 that specializes in automated and personalized lifestyle and nutrition coaching. Its platform leverages proprietary artificial intelligence to create tailored diet plans that cater to users' individual goals, dietary preferences, and restrictions. The application facilitates precision eating by offering personalized meal plans, smart shopping lists, recipe suggestions, and restaurant recommendations. By encoding dietary programs as rulesets, Suggestic enables health-related organizations to efficiently build and deliver customized nutrition programs through white label solutions or direct API integration. The platform also supports data acquisition from users through assessments and lab tests, allowing it to provide relevant food recommendations that assist individuals in weight management, enhancing vitality, and preventing or reversing chronic diseases.

Vincere Health

Seed Round in 2021
Vincere Health Inc. is a health technology company based in Allston, Massachusetts, founded in 2019 at the Harvard Innovation Labs. The company specializes in developing a health engagement platform aimed at assisting users in quitting smoking and making healthier choices. Its application combines behavioral nudges, evidence-based interventions, and personalized coaching, allowing users to set individual goals and monitor their progress. Users engage with the platform by using an attachable breathalyzer device to verify adherence to their smoking reduction goals. The application incentivizes users with periodic financial rewards for reducing their smoking and achieving cessation. By leveraging real-time health data and intelligent incentives, Vincere Health addresses significant healthcare challenges, particularly in smoking cessation and chronic disease management.

Options MD

Pre Seed Round in 2021
Options MD is a telemedicine platform that employs AI-driven algorithms to match individuals with severe or treatment-resistant mental illnesses to personalized care options. It then connects these patients with in-house psychiatric experts for appropriate medical assistance.

Cured

Series A in 2021
Cured, Inc. is a healthcare technology company that specializes in digital marketing and customer relationship management solutions for the healthcare sector. Founded in 2018 and headquartered in San Francisco, California, with additional offices in Chicago and Denver, Cured develops a cloud-based platform that integrates various tools to enhance patient engagement and streamline operations for healthcare organizations. The company's offerings include network management, patient marketing, and insights, aimed at improving customer experiences and healthcare outcomes. By creating custom content and utilizing pre-built templates, Cured enables healthcare providers to foster better interactions with patients and unify processes and technology to enhance efficiencies and care quality.

MedZoomer

Pre Seed Round in 2021
MedZoomer operates a prescription delivery platform that facilitates on-demand medication delivery from local pharmacies directly to customers' doorsteps.

Kintsugi

Seed Round in 2021
Kintsugi is a company focused on advancing mental healthcare through innovative technology. It specializes in developing voice biomarker software designed to detect signs of depression and anxiety from brief samples of natural speech. Recognized for its AI advancements, Kintsugi aims to bridge gaps in mental health care within various health systems. By providing tools that enable quicker and more accurate diagnoses, the company seeks to enhance efficiency and potentially save lives.

Rezilient Health

Seed Round in 2021
Rezilient Health combines the accessibility of telehealth with comprehensive in-person care. It operates neighborhood hubs where patients can access virtual consultations with their doctors alongside physical examinations, lab tests, and imaging services.

Dieta Health

Pre Seed Round in 2021
Dieta Health operates a healthcare technology platform and mobile application that provides personalized digestive health recommendations for individuals with Irritable Bowel Syndrome. The platform collects high‑resolution data on users’ diet, bowel movements, medications, and other factors, aggregates insights across a broad user network, and uses machine learning to tailor recommendations to each user’s path toward symptom relief and improved quality of life.

Nice Healthcare

Seed Round in 2021
Nice Healthcare LLC is a nurse practitioner-led primary care clinic based in Minneapolis, Minnesota, founded in 2017. The company focuses on providing comprehensive healthcare solutions for small and medium-sized businesses through innovative technology and in-home care. Its services include virtual and in-home primary care, virtual mental health therapy, and virtual physical therapy. Patients can access these services via a subscription model, allowing them to schedule video or in-person visits with licensed and certified nurse practitioners or physician assistants. This approach enables individuals to receive seamless and convenient healthcare tailored to their needs.

Spora Health

Seed Round in 2021
Founded in 2019, Spora Health is a San Francisco-based telemedicine provider specializing in primary care for people of color. It offers treatments for various conditions such as allergies, infections, and skin issues, using machine learning-driven technology to predict patient risk profiles.

Polygon

Seed Round in 2021
Polygon, founded in 2019 and headquartered in Los Angeles, California, focuses on providing remote diagnostic services for individuals with learning differences such as dyslexia and ADHD. The company employs licensed psychologists to conduct comprehensive self-assessments, delivering personalized reports that include diagnoses and intervention strategies. Polygon's mission is to equip individuals with the necessary tools for success, ranging from initial diagnosis to ongoing support, thereby enhancing their capacity to thrive in educational environments.

Spora Health

Seed Round in 2020
Founded in 2019, Spora Health is a San Francisco-based telemedicine provider specializing in primary care for people of color. It offers treatments for various conditions such as allergies, infections, and skin issues, using machine learning-driven technology to predict patient risk profiles.

Reema Health

Pre Seed Round in 2020
Reema Health is a technology startup focused on bridging the gaps between healthcare and social care. The company operates a healthcare platform that utilizes tech-enabled community guides to connect individuals with essential care and resources. By offering a personalized, community-based approach, Reema Health empowers users to identify specific actions needed to improve their behavioral health. This innovative platform aims to facilitate easier access to medical care and enhance the overall well-being of its users.
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