NRW.Bank

Vytal provides software‑enabled reusable packaging solutions that replace single‑use containers in the food and beverage sector. The company offers a reusable container system coupled with container‑management software to support sustainable takeaway and delivery operations. Its platform operates on a pay‑per‑use model that is cheaper than disposable alternatives, allowing restaurants, supermarkets, caterers, canteens and event organisers to borrow containers for free and return them at designated locations or through delivery services. By enabling convenient borrowing and returning, Vytal maximises both economic and ecological value while reducing packaging waste.

Pilzling is an urban mushroom farm that cultivates gourmet mushrooms using local waste materials like coffee grounds and wood shavings. It converts these into nutrient-rich substrates, reducing waste while producing high-quality fungi.

ScrapBees is a pick-up service for recycling scrap metal from public and private residences and businesses. When it comes to converting what was formerly deemed waste into raw material, they are a trustworthy partner for artisans, private homes, and entrepreneurs. the first scrapyard on wheels in the world, quick, technologically advanced, and practical.

Alteva is a technology company specializing in the development of advanced battery cells. Its primary focus is on creating high-energy density, safety-conscious batteries tailored for the decarbonization of hard-to-electrify transport sectors such as aviation and heavy-duty vehicles. The company's innovative approach involves the use of ultralight carbon materials and sustainable raw materials, aiming to enhance battery performance, longevity, and compatibility with existing production facilities.

Refoxy Pharma develops therapeutic medicines intended to treat age-related diseases and promote healthy longevity. It researches proteins that regulate multiple genes involved in stress resistance and metabolism and develops novel modulators of a central stress response pathway to influence aging through genetics, with the aim of extending the years of healthy living for patients.

GEMESYS, a German tech company, specializes in developing advanced AI chips. Founded as a spin-off from Ruhr-University Bochum, the company leverages memristors, novel electronic components, to create highly efficient neural network processing systems. Their technology enables on-device AI training and inference, opening up new possibilities for Edge AI applications.

Valuedesk provides a company-wide solution for recording, analyzing, and implementing improvements and savings. Its platform enables transparency and communication for teamwork and is complemented by workshops, targeted methodological training, and seminars. The solution is used across industries such as automotive suppliers, biotechnology, energy and environment, food, furniture, construction, chemicals and raw materials, information technology, transport and logistics, telecommunications, electronics, pharmaceuticals and cosmetics, machine and plant construction, and textiles. Founded in 2017 and based in Bielefeld, Germany, Valuedesk specializes in structured savings and operations efficiency management, applying systematic approaches to identify improvement opportunities, develop implementation concepts, and support clients with consulting and process management software to achieve long-term profitability.

4TEEN4 Pharmaceuticals develops precision medicines for acute cardiovascular conditions, focusing on restoring cardiac and vascular function in critical care by creating humanized antibodies and related biomarkers and diagnostic tools. Its lead program, Procizumab, is a humanized antibody targeting DPP3 for the treatment of acute cardiovascular diseases. It also develops DPP3 as a diagnostic biomarker for indications such as acute heart failure, myocardial infarction, cardiogenic shock, and septic shock, along with accompanying diagnostic tools. The company evolved from Sphingotec Therapeutics and is based in Hennigsdorf, Germany.

Eco2Grow is a company that assists industrial small and medium-sized enterprises (SMEs) in navigating the challenges posed by the renewable energy transition. It provides these businesses with direct access to green electricity sourced from solar and wind farms, allowing them to secure energy at long-term fixed wholesale prices. By combining energy procurement with energy management solutions, Eco2Grow enables its clients to obtain sustainable energy while reducing pollution and achieving their climate objectives.

Black Semiconductor is a technology company focused on graphene integrated photonics. It develops photonic circuits directly fabricated on silicon-scale electronics, enabling chip-to-chip communication at higher data transfer rates, over longer distances, with reduced energy consumption. By combining electronics and photonics on a single wafer, the company aims to overcome bandwidth and energy limits of traditional copper interconnects. The approach uses graphene to connect electrical signals and light, offering CMOS-compatible processing that fits into existing chip production pipelines. This enables faster, more energy-efficient data transfer and scalable integration for data centers and other computing applications. The company is advancing a scalable 300mm wafer pilot line and has established fabrication facilities in Aachen, Germany (FabOne) to support scalable production.

Cylib is a Greentech startup focused on transforming lithium-ion battery recycling in Europe. The company offers battery recycling services designed to support the green energy transition by efficiently recovering raw materials during the recycling process. This high-efficiency approach significantly reduces the carbon footprint associated with the entire battery value chain. By enhancing the sustainability of electric vehicle manufacturing, Cylib aims to decrease reliance on mining new raw materials, thereby contributing to a more sustainable electric mobility industry.

Prothea Technologies is a private medical technology company focused on innovating solutions for lung cancer diagnosis and treatment. Its primary offering is a specialized medical device that integrates a Microendoscope with an advanced image processing system. This technology enhances visualization during procedures, allowing for in situ analysis of lesion structures at a molecular level. By streamlining the biopsy and therapy process into a single hospital visit, Prothea Technologies aims to improve medical outcomes for lung cancer patients, facilitating more efficient and effective care.

CryoTherapeutics GmbH, founded in 2009 and based in Cologne, Germany, specializes in the development of a proprietary cryotherapy system aimed at treating coronary artery disease, a major cause of heart attacks. The company focuses on demonstrating the clinical benefits and ensuring the safety and efficacy of cryoenergy in the cardiovascular system. Its novel catheter system utilizes cryo energy to treat and prevent heart attacks, offering a promising approach to addressing the challenges posed by diseased coronary arteries. Through its early-stage commercialization efforts, CryoTherapeutics aims to enhance treatment options for heart surgeons and improve patient outcomes in cardiovascular health.

widu enables real estate and accommodation companies to source visuals (photography, video, drone) at scale through its serviced marketplace

Companyon Analytics provides data security, cloud infrastructure, information technology, technical solutions, and consultancy services.

Consalio is a company that specializes in advisory spend management through its SaaS-based platform. The platform provides organizations with full transparency regarding ongoing advisor activities and associated costs, allowing management to monitor and control spending before bills are received. By offering real-time analysis of external consulting costs, Consalio enables companies to identify potential savings, compare advisory projects, and enhance negotiation effectiveness with external partners. This transparency facilitates better communication between companies and their advisors, ensuring that project scopes remain manageable and resources for advisory services are optimized. Consalio's solution ultimately helps organizations improve their financial oversight and decision-making in relation to external consultancy engagements.

bNear is a virtual office platform that integrates seamlessly with Microsoft Teams. It fosters efficient communication and collaboration among hybrid and remote teams, promoting information sharing, creativity, team spirit, and motivation.

Elixion Medical develops medical IoT software and wireless catheter-connected sensors to automate bedside patient monitoring and detect complications early. Its platform provides real-time fluid output tracking, AI-backed predictive analytics, and automated documentation to streamline nursing and physician workflows, reduce routine tasks, identify anomalies sooner, and improve patient care efficiency in hospitals and care units.

talpasolutions a predictive SaaS analytics provider for the mining industry that helps companies optimize machine performance, reduce breakdowns, and improve safety by making data more understandable. talpasolutions makes it possible for operators and machine manufacturers in heavy industry to use machine data that would have otherwise been lost. talpasolutions concentrates on building visualization and analysis applications for the industrial internet. In the first step, large amounts of data from the machines are recorded. Comprehendable visualizations allow for different stakeholders to understand relationships based on sensor data and contextual data and to react to critical information, which would otherwise have been buried in the data transfer. In the second step the newest predictive models are applied to eliminate events such as errors and the breakdown of machines critical to the process. This increases not only the availability but also the workload of the machines. talpasolutions has built a network out of industry partners to develop solutions that stretch across various sectors and unify industry experience, data science, and workflow connectivity. Using predictive instructions our platform recognizes problems before they occur and supports users with workflow-based processes. Our applications make it possible to collect performance data from machines in order to recommend optimal fleet combinations for respective scenarios to customers. This leads to more operating hours, higher efficiency, and an improved lifetime value of the machines.

Machine2Human Solutions specializes in AI-driven customer relationship management (CRM) enhancement. Their core product is an intelligent knowledge processing platform that facilitates decision-making and problem-solving through speech analysis during customer interactions. This platform also automates documentation processes and creates knowledge bases, allowing companies to effectively communicate their expertise using advanced machine learning and natural language processing techniques.

Refined Laser Systems is a specialized manufacturer of biophotonics devices, focusing on stain-free tissue diagnostics using its proprietary fiber-based tunable picosecond laser technology. The company's innovative laser systems enable rapid and reliable diagnoses, significantly reducing the time required compared to traditional methods.

VMRay is a cybersecurity company that builds hypervisor‑based, agentless sandboxing solutions for dynamic malware analysis. Its flagship product, VMRay Analyzer, runs suspicious code in a protected virtual environment that is invisible to the malware, allowing the system to capture a complete record of all interactions. The platform delivers precise, noise‑free detection and supports incident response, digital forensics, and threat intelligence. Additional offerings include VMRay Detector for automated threat detection, VMRay Investigator for forensic investigation, and VMRay Email Threat Defender to block phishing and targeted email attacks. By automatically analyzing and blocking malicious network traffic, VMRay protects enterprise assets, infrastructure, and intellectual property while providing actionable intelligence for security teams at all levels.

Certif-ID International GmbH operates an online platform that facilitates the issuance of blockchain-based digital certificates and badges. The company aims to create a skills ecosystem that connects educators, industries, and candidates, enabling effective sourcing, management, and development of talent aligned with industry standards. By leveraging the European ESCO framework, Certif-ID harmonizes job profiles and matches skills to job requirements. Its intelligent matching engine uses data to link candidates with suitable job opportunities, while the SkillPass feature allows candidates to showcase their qualifications, including video interviews and project work. The platform supports companies in managing internal talent development and addressing skills shortages, particularly in developing markets. Through its interconnected network of training and industry partners, Certif-ID enhances transparency in credential verification and streamlines cross-border recruitment efforts.

Resolve BioSciences GmbH, founded in 2016 and based in Monheim am Rhein, Germany, specializes in spatial multiomics analysis platforms that enhance the understanding of single-cell spatial biology. The company's innovative technology enables researchers to obtain high-resolution spatial views of subcellular gene expression activities. Resolve BioSciences offers a range of services that encompass bioinformatics, imaging, genomics, transcriptomics, histology, and pathology, among others. Their expertise extends to various fields, including neuroscience, oncology, infectious diseases, and agrigenomics, facilitating advanced studies in cell atlasing and single-cell analysis.

CatchHR is a technology company specializing in AI-driven recruitment solutions. It offers applicant search, selection, management, active sourcing, and personality matching features through its mobile application, which accesses over 600 online channels.

Consalio is a company that specializes in advisory spend management through its SaaS-based platform. The platform provides organizations with full transparency regarding ongoing advisor activities and associated costs, allowing management to monitor and control spending before bills are received. By offering real-time analysis of external consulting costs, Consalio enables companies to identify potential savings, compare advisory projects, and enhance negotiation effectiveness with external partners. This transparency facilitates better communication between companies and their advisors, ensuring that project scopes remain manageable and resources for advisory services are optimized. Consalio's solution ultimately helps organizations improve their financial oversight and decision-making in relation to external consultancy engagements.

Drop Friends is an app that accepts packages for your community and ties them to an office or hotel at the time of delivery. It is a platform for parcel shipments.

ichó systems gmbh is a company based in Duisburg, Germany, specializing in the development of interactive systems aimed at promoting and activating individuals with cognitive impairments, particularly those suffering from dementia, stroke, or Parkinson's disease. Its flagship product, the ichó therapy ball, utilizes advanced sensor technology to respond to various interactions such as rolling, catching, or shaking, with visual and auditory stimuli like colored lights, vibrations, sounds, and music. The therapy ball is equipped with multiple applications designed to enhance motor and cognitive skills, developed in collaboration with healthcare professionals. Since its market introduction in 2020, ichó has been implemented in over 850 care facilities, receiving endorsements from medical professionals for its effectiveness. In 2023, the therapy program was recognized and funded by care insurance as a preventive service. ichó aims to facilitate outpatient care, allowing patients to engage in therapeutic activities comfortably at home.

Fimo Health develops a data-driven health platform that helps chronic disease patients manage fatigue by tracking symptoms, analyzing data with AI, and providing therapeutic exercises. The solution supports Long Covid, Multiple Sclerosis and ME/CFS, with a CE-certified option for Long Covid, and plans to extend to Oncology. The app combines patient-reported data with scientific insights to deliver personalized guidance and monitoring. It is reimbursed by multiple health insurers, covering more than 20 million members.

Einhundert Energy is a company based in Cologne, Germany, specializing in smart services for green and digital energy supply. Established in 2017, it focuses on providing comprehensive solutions for tenant electricity, which includes planning, installation, operation, and maintenance of photovoltaic systems. The company enables tenants and entrepreneurs to access low-cost solar energy while ensuring transparency in their energy billing through a dedicated app. This app allows users to monitor their power consumption effectively, promoting cost control and efficiency. Einhundert Energy's digital billing solution integrates various technologies, including heat and water billing, smoke detectors, heat pumps, and e-charging stations, catering to the diverse needs of property managers and tenants alike.

Emergence Therapeutics AG is a biopharmaceutical company based in Duisburg, Germany, focused on developing innovative antibody-drug conjugates (ADCs) to address high-need cancers. Established in 2019, the company leverages advanced technologies in antibody design, linker systems, and therapeutic payloads to create targeted treatments. Its lead program specifically targets Nectin-4, a clinically validated marker for various cancers, utilizing a highly specific antibody in combination with optimized linker technology and amanitin as the payload. This approach aims to provide effective therapeutic options for challenging cancer types. Emergence Therapeutics is also exploring opportunities to develop additional first- or best-in-class ADCs to meet unmet medical needs in oncology.

Ducktrain is a developer of electric semi-autonomous delivery technology aimed at enhancing logistics transportation over longer distances in urban and industrial settings. The company offers innovative vehicle platforms and automation solutions that facilitate efficient and environmentally friendly logistics operations, promoting zero emissions. Ducktrain's technology not only modernizes urban logistics but also provides the capability to upgrade hardware and software, ensuring continuous efficiency and functionality for transporters. By utilizing a unique system where multiple vehicle platforms, referred to as "ducks," can form a train, Ducktrain optimizes the transportation process, ultimately transforming the landscape of urban and industrial logistics.

Operaize GmbH, based in Cologne, Germany, specializes in developing an artificial intelligence platform known as Cognitive Operations. This cloud-based solution is designed to enhance production planning for manufacturing clients by integrating seamlessly with existing planning infrastructures through APIs or SAP integration. Cognitive Operations effectively collects and transforms planning and master data from various ERP and planning systems into a format that supports AI-driven optimization processes. By analyzing a range of constraints and objectives, the platform generates optimal production plans in seconds. Additionally, Operaize's technology empowers clients to proactively identify faults, risks, and failures within their operations, facilitating informed decision-making and efficient problem-solving strategies throughout the industrial value chain.

Coachinho is an AI-driven football coaching platform focused on player development and coaching education. It offers training games with real-time feedback, personalized training plans by position, skill level, and age group, and access to courses, drills, workouts, and masterclasses created by professional players. The platform helps aspiring players and coaches improve ball handling, agility, peripheral vision, and overall performance by analyzing performance and delivering tailored recommendations. It combines a library of drills and tactical content with interactive sessions to tailor training to individual needs. Users include players seeking skill enhancement and coaches overseeing development programs.

Abalos Therapeutics GmbH is a biotechnology company based in Essen, Germany, focused on the development of immuno-oncology therapeutics. Established in 2019, the company specializes in creating arenavirus-based drug candidates aimed at activating immune responses against cancerous tumors and metastases. Utilizing its proprietary Fast Evolution platform, Abalos Therapeutics generates virus strains with optimized anti-tumoral properties. The company's innovative approach to virotherapy seeks to harness the immune stimulation capabilities of arenaviruses, enabling the immune system to specifically target and eliminate malignant tumor tissue. Through its advanced therapeutic candidates, Abalos Therapeutics aims to provide new treatment options for cancer patients.

Lumoview Building Analytics GmbH, founded in 2019 and based in Cologne, Germany, specializes in indoor measurement systems designed for automated building analysis. The company has developed a device that can digitize a room in just two seconds, making it accessible for widespread use. Once the data is collected, it is analyzed in the cloud using advanced automation. Lumoview's connected online platform enables building owners to make informed decisions to enhance building performance and reduce CO2 emissions, contributing to more sustainable building management.

CEVEC Pharmaceuticals GmbH is a biopharmaceutical company based in Cologne, Germany, specializing in the production of therapeutic proteins and monoclonal antibodies using a unique human cell-based expression system. Founded in 2001, CEVEC has developed the CAP-GO platform, which allows for the efficient production of complex, glycosylated proteins that are challenging to express using conventional cell lines. This platform includes optimized expression vectors, serum- and animal component-free cell line generation, and stable pool generation for recombinant proteins. Additionally, CEVEC offers the CAP-GT platform, facilitating large-scale production of gene therapy vectors, including Lentiviral, Adenoviral, and AAV types. The company also provides contract manufacturing services and has established a strategic collaboration with BioLamina AB, enhancing its capabilities in the biopharmaceutical sector.

Masterplan.com develops a SaaS platform for corporate education, offering practical lessons on diverse content, short learning sessions, and e-learning videos with hands-on knowledge reviews to facilitate integration of digital learning into everyday work practices.

Aifora GmbH is a technology company based in Düsseldorf, Germany, specializing in retail automation through its advanced optimization software. Founded in 2017, Aifora's platform leverages big data and machine learning to help retail businesses understand and predict consumer behavior effectively. It offers solutions for price optimization and stock management, assisting clients in determining optimal order quantities and improving merchandise flow. By creating a shared data ecosystem, Aifora enables brands and retailers to make informed decisions that enhance consumer experiences and drive profitability. The company's use of deep learning algorithms allows for more accurate pricing and promotional strategies, while intelligent automation streamlines repetitive tasks, allowing merchandisers to concentrate on product innovation and enhancing customer engagement.

Founded in 2015, Semalytix develops an AI-driven platform that extracts and summarizes trends in value perception of high-cost therapies across areas such as oncology, immunology, and metabolism. The platform gathers evidence from diverse data sources like CRM systems, social media, clinical studies, and external providers.

eevie provides a proactive eco-guide aimed at promoting sustainable living. The platform encourages individuals to make mindful choices through actionable insights that highlight the impact of daily decisions on their carbon footprints, covering areas such as commuting, local sourcing, and plastic use reduction. By leveraging machine learning, eevie tailors guidance based on users' daily routines, ensuring relevant and timely support rather than generic solutions. This approach fosters a deeper awareness of environmental issues and facilitates the development of eco-friendly habits over time. Additionally, eevie offers a business-to-business SaaS platform that helps organizations implement customized climate engagement programs, promoting a climate-friendly work culture, measuring emissions, and contributing to environmental, social, and governance (ESG) strategies. Through its technology, eevie aims to unite a global community in the pursuit of sustainable practices, empowering individuals and businesses alike to make meaningful contributions to environmental protection.

It's better to have a conversation. We help brands to pioneer Conversational Commerce by using WhatsApp. Send out WhatsApp newsletters to your audience. Sell your product or service customers in chat. Engage with your customers directly where their friends are. A conversational commerce suite for consumer brands, who want to talk and build relationships with their customers. We guide brands from setup to sales ready and enable your next marketing and sales channel. 100% personalized.

Coachinho is an AI-driven football coaching platform focused on player development and coaching education. It offers training games with real-time feedback, personalized training plans by position, skill level, and age group, and access to courses, drills, workouts, and masterclasses created by professional players. The platform helps aspiring players and coaches improve ball handling, agility, peripheral vision, and overall performance by analyzing performance and delivering tailored recommendations. It combines a library of drills and tactical content with interactive sessions to tailor training to individual needs. Users include players seeking skill enhancement and coaches overseeing development programs.

talpasolutions a predictive SaaS analytics provider for the mining industry that helps companies optimize machine performance, reduce breakdowns, and improve safety by making data more understandable. talpasolutions makes it possible for operators and machine manufacturers in heavy industry to use machine data that would have otherwise been lost. talpasolutions concentrates on building visualization and analysis applications for the industrial internet. In the first step, large amounts of data from the machines are recorded. Comprehendable visualizations allow for different stakeholders to understand relationships based on sensor data and contextual data and to react to critical information, which would otherwise have been buried in the data transfer. In the second step the newest predictive models are applied to eliminate events such as errors and the breakdown of machines critical to the process. This increases not only the availability but also the workload of the machines. talpasolutions has built a network out of industry partners to develop solutions that stretch across various sectors and unify industry experience, data science, and workflow connectivity. Using predictive instructions our platform recognizes problems before they occur and supports users with workflow-based processes. Our applications make it possible to collect performance data from machines in order to recommend optimal fleet combinations for respective scenarios to customers. This leads to more operating hours, higher efficiency, and an improved lifetime value of the machines.

It's better to have a conversation. We help brands to pioneer Conversational Commerce by using WhatsApp. Send out WhatsApp newsletters to your audience. Sell your product or service customers in chat. Engage with your customers directly where their friends are. A conversational commerce suite for consumer brands, who want to talk and build relationships with their customers. We guide brands from setup to sales ready and enable your next marketing and sales channel. 100% personalized.

Social Impact Network is a fully decentralized ecosystem for impact investing. Social Impact Network empowers impact investors to earn high returns while effortlessly making a positive social impact.

Lumoview Building Analytics GmbH, founded in 2019 and based in Cologne, Germany, specializes in indoor measurement systems designed for automated building analysis. The company has developed a device that can digitize a room in just two seconds, making it accessible for widespread use. Once the data is collected, it is analyzed in the cloud using advanced automation. Lumoview's connected online platform enables building owners to make informed decisions to enhance building performance and reduce CO2 emissions, contributing to more sustainable building management.

Limbiq provides a browser-based Software-as-a-Service solution focused on supply chain management for B2B clients in various sectors, including industry, trade, and logistics. The company develops artificial intelligence-driven software that digitizes workflow and document management, enhancing operational efficiency. Limbiq's platform integrates all relevant partners, from suppliers to logistics service providers and end customers, facilitating seamless communication and collaboration. This comprehensive tool offers businesses transparency and real-time tracking of goods throughout the entire supply chain, enabling them to optimize their logistics and improve overall performance.

ichó systems gmbh is a company based in Duisburg, Germany, specializing in the development of interactive systems aimed at promoting and activating individuals with cognitive impairments, particularly those suffering from dementia, stroke, or Parkinson's disease. Its flagship product, the ichó therapy ball, utilizes advanced sensor technology to respond to various interactions such as rolling, catching, or shaking, with visual and auditory stimuli like colored lights, vibrations, sounds, and music. The therapy ball is equipped with multiple applications designed to enhance motor and cognitive skills, developed in collaboration with healthcare professionals. Since its market introduction in 2020, ichó has been implemented in over 850 care facilities, receiving endorsements from medical professionals for its effectiveness. In 2023, the therapy program was recognized and funded by care insurance as a preventive service. ichó aims to facilitate outpatient care, allowing patients to engage in therapeutic activities comfortably at home.

COMPEON is a prominent financing portal in Germany that specializes in providing tailored financial solutions for small and medium-sized enterprises (SMEs). Established in 2013, the platform enables businesses to submit financing queries at no cost, receiving customized offers from a network of over 220 banks, leasing companies, and alternative financing providers. Each year, COMPEON manages financing inquiries amounting to €2.5 billion, facilitating access to various financial products including credit, loans, leasing agreements, factoring, and alternative financing options such as mezzanine capital and project financing. The firm is led by its founders and managing directors, Kai Böringschulte, Dr. Nico Peters, and Dr. Frank Wüller, and is supported by notable investors including DvH Ventures, b-to-v, and Tengelmann Ventures.

Ubirch develops an Internet of Things software security system using blockchain technology. It provides software for secure data transmission from IoT sensors, serving industries such as production, insurance, energy, supply chain, and logistics. Additionally, Ubirch offers a platform for publishing and sharing carbon footprint data, enabling companies to calculate their Scope 3 emissions and publish them in an auditable manner.

Lumoview Building Analytics GmbH, founded in 2019 and based in Cologne, Germany, specializes in indoor measurement systems designed for automated building analysis. The company has developed a device that can digitize a room in just two seconds, making it accessible for widespread use. Once the data is collected, it is analyzed in the cloud using advanced automation. Lumoview's connected online platform enables building owners to make informed decisions to enhance building performance and reduce CO2 emissions, contributing to more sustainable building management.

CHRONEXT operates as a comprehensive platform for trading luxury watches. It facilitates buying, selling, and servicing of timepieces through its in-house certified watchmaking atelier. The platform offers brand new models alongside pre-owned and vintage pieces, all inspected for quality and authenticity.

Abalos Therapeutics GmbH is a biotechnology company based in Essen, Germany, focused on the development of immuno-oncology therapeutics. Established in 2019, the company specializes in creating arenavirus-based drug candidates aimed at activating immune responses against cancerous tumors and metastases. Utilizing its proprietary Fast Evolution platform, Abalos Therapeutics generates virus strains with optimized anti-tumoral properties. The company's innovative approach to virotherapy seeks to harness the immune stimulation capabilities of arenaviruses, enabling the immune system to specifically target and eliminate malignant tumor tissue. Through its advanced therapeutic candidates, Abalos Therapeutics aims to provide new treatment options for cancer patients.

Frontastic is a company that specializes in Frontend-as-a-Service, focusing on enhancing the digital customer experience with a mobile-first approach. Its platform allows online retailers, brands, marketplaces, and agile start-ups to create customer-centric websites with minimal IT effort. By facilitating seamless API integration, Frontastic provides a simple-to-use interface that empowers developers to tailor websites to their specific needs. This innovative solution has quickly positioned Frontastic as a leading front-end development platform in the API economy, enabling companies to establish and strengthen their online presence effectively.

Social Impact Network is a fully decentralized ecosystem for impact investing. Social Impact Network empowers impact investors to earn high returns while effortlessly making a positive social impact.

HoloBuilder provides an AI-driven software solution for construction site progress documentation. Its platform enables users to capture, communicate, and control project progress using 360° photos, improving processes and helping stay on schedule and within budget.

Taxy.io develops a software platform that automates tax consulting and research using artificial intelligence. It serves tax professionals, lawyers, auditors, and corporate finance departments by providing a central hub for digital tax intelligence through semantic search and automated legal analysis.

Einhundert Energy is a company based in Cologne, Germany, specializing in smart services for green and digital energy supply. Established in 2017, it focuses on providing comprehensive solutions for tenant electricity, which includes planning, installation, operation, and maintenance of photovoltaic systems. The company enables tenants and entrepreneurs to access low-cost solar energy while ensuring transparency in their energy billing through a dedicated app. This app allows users to monitor their power consumption effectively, promoting cost control and efficiency. Einhundert Energy's digital billing solution integrates various technologies, including heat and water billing, smoke detectors, heat pumps, and e-charging stations, catering to the diverse needs of property managers and tenants alike.

Unu GmbH, founded in 2013 and headquartered in Berlin, Germany, specializes in the design, development, and sale of electric scooters. The company aims to enhance urban mobility by providing stylish, emission-free, and quiet scooters that feature portable batteries, allowing users to charge them conveniently at home. Unu's first electric scooter was launched in 2014, marking the beginning of its commitment to connecting people with their cities. In addition to selling scooters through retail outlets and online, the company offers various financing options and after-sales support services to enhance customer experience.

ichó systems gmbh is a company based in Duisburg, Germany, specializing in the development of interactive systems aimed at promoting and activating individuals with cognitive impairments, particularly those suffering from dementia, stroke, or Parkinson's disease. Its flagship product, the ichó therapy ball, utilizes advanced sensor technology to respond to various interactions such as rolling, catching, or shaking, with visual and auditory stimuli like colored lights, vibrations, sounds, and music. The therapy ball is equipped with multiple applications designed to enhance motor and cognitive skills, developed in collaboration with healthcare professionals. Since its market introduction in 2020, ichó has been implemented in over 850 care facilities, receiving endorsements from medical professionals for its effectiveness. In 2023, the therapy program was recognized and funded by care insurance as a preventive service. ichó aims to facilitate outpatient care, allowing patients to engage in therapeutic activities comfortably at home.

Jamata Events UG is a company based in Lünen, Germany, founded in 2015. It operates a community platform designed for event organizers and users. The platform enables event organizers to list their events while providing users with the ability to search for various events and purchase tickets from multiple ticket providers. By aggregating event data from major ticket providers worldwide, Jamata Events facilitates the discovery of music events and allows bands, promoters, and event planners to effectively promote their offerings.

Holocafé ist a franchiser company developing exclusive, shared-space VR experiences for location-based entertainment. Content aside, we have developed an entire one-stop platform solution to provide leisure operators with all tools they need: From ticketing and online payment over staff scheduling and accounting to store automization and content distribution. We are presently running three pilot stores in Germany with a fourth one scheduled to open this spring, in addition to a number of international licensees.

Banking One develops a sales management platform for retail banks that uses predictive analytics to identify customers most likely to be interested in financial products. The platform enables sales managers to filter and assign high-potential prospects to sales agents, supporting targeted outreach at the right time with the right product. By optimizing sales campaigns and coordinating the bank’s sales team, the solution seeks to improve campaign effectiveness, increase earnings for banks, and enhance customer experience by reducing unnecessary contacts.

Hemovent is a medical technology company based in Aachen, Germany, focused on developing a portable ECMO (Extra Corporeal Membrane Oxygenation) unit. Founded by Christof Lenz and Oliver Marseille, the company aims to create an innovative device that supports or replaces heart and lung functions during cardiac or respiratory failure. Hemovent's device is designed to provide respiratory support for patients with severely damaged lungs and serves as a temporary life support system, taking over heart function in cases of acute heart failure. This technology enables hospitals to stabilize patients and address underlying health issues effectively, while also allowing for increased patient mobility during treatment.

Unu GmbH, founded in 2013 and headquartered in Berlin, Germany, specializes in the design, development, and sale of electric scooters. The company aims to enhance urban mobility by providing stylish, emission-free, and quiet scooters that feature portable batteries, allowing users to charge them conveniently at home. Unu's first electric scooter was launched in 2014, marking the beginning of its commitment to connecting people with their cities. In addition to selling scooters through retail outlets and online, the company offers various financing options and after-sales support services to enhance customer experience.

ShopCo Technologies Corp. is a technology company based in San Francisco, California, that specializes in enhancing the online shopping experience through its innovative browser extension. The extension features a one-click buy button powered by artificial intelligence, which streamlines the purchasing process by automatically completing transactions on various websites. Founded in 2014 by Jay Habib, ShopCo offers a universal shopping cart that consolidates items from multiple online retailers into a single platform, enabling users to browse and check out seamlessly from one location. Additionally, the company prioritizes user security by employing encryption methods and two-step verification to protect sensitive data. ShopCo Technologies operates as a subsidiary of Klarna Bank AB, further integrating its services within the e-commerce ecosystem.

CardioSecur, a subsidiary of Personal MedSystems, specializes in innovative mobile health solutions, particularly in the realm of instant cardiac monitoring. The company develops a smartphone-based ECG application that is designed to provide personalized cardiac monitoring services. This application is accompanied by a set of electrodes, allowing users to conduct high-level 12-lead ECG tests with ease. One of the key features of the application is its ability to share data with healthcare professionals, enabling patients to receive timely recommendations based on their cardiac health within minutes. CardioSecur's focus on user-friendly design and sophisticated technology positions it as a leader in the field of personalized ECG systems for individual use.

Mapudo is an independent online marketplace focused on the metals supply industry, specializing in the trading and processing of steel. By creating a standardized platform for product searches, Mapudo connects buyers and sellers of various metals, facilitating the procurement process for both parties. This innovative approach simplifies the buying and selling of steel products, enabling dealers and buyers to conduct transactions online efficiently. Mapudo aims to streamline the metals supply chain, ultimately saving time and money for all participants in the market.

Rigontec GmbH is a biopharmaceutical company based in Planegg, Germany, focused on developing RNA-based immunotherapeutics for cancer and viral diseases. Founded in 2014, the company is recognized for its innovative approach to immuno-oncology, particularly through its lead compound ImOl100. This compound acts as a stimulator of the immune receptor retinoic acid-inducible gene I (RIG-I), which detects viral RNA and promotes immune responses. ImOl100 serves as a minimal mimic of naturally occurring 3pRNA, a motif commonly found in viral RNAs, and aims to overcome the limitations associated with traditional cancer vaccines and checkpoint inhibitors. As of October 2017, Rigontec operates as a subsidiary of Merck & Co., enhancing its capabilities in the development of effective therapeutic options for patients.

CryoTherapeutics GmbH, founded in 2009 and based in Cologne, Germany, specializes in the development of a proprietary cryotherapy system aimed at treating coronary artery disease, a major cause of heart attacks. The company focuses on demonstrating the clinical benefits and ensuring the safety and efficacy of cryoenergy in the cardiovascular system. Its novel catheter system utilizes cryo energy to treat and prevent heart attacks, offering a promising approach to addressing the challenges posed by diseased coronary arteries. Through its early-stage commercialization efforts, CryoTherapeutics aims to enhance treatment options for heart surgeons and improve patient outcomes in cardiovascular health.

CHRONEXT operates as a comprehensive platform for trading luxury watches. It facilitates buying, selling, and servicing of timepieces through its in-house certified watchmaking atelier. The platform offers brand new models alongside pre-owned and vintage pieces, all inspected for quality and authenticity.

Hemovent is a medical technology company based in Aachen, Germany, focused on developing a portable ECMO (Extra Corporeal Membrane Oxygenation) unit. Founded by Christof Lenz and Oliver Marseille, the company aims to create an innovative device that supports or replaces heart and lung functions during cardiac or respiratory failure. Hemovent's device is designed to provide respiratory support for patients with severely damaged lungs and serves as a temporary life support system, taking over heart function in cases of acute heart failure. This technology enables hospitals to stabilize patients and address underlying health issues effectively, while also allowing for increased patient mobility during treatment.

Bomedus is a Germany-based medical device company founded in 2011, focused on improving mobility for individuals suffering from chronic back pain. The company develops innovative devices that utilize an electro-therapeutic method to provide permanent and sustainable pain reduction. By non-invasively modulating pathologically altered neuronal impulses, Bomedus aims to enhance the quality of life for patients dealing with pain-related challenges.

CHRONEXT operates as a comprehensive platform for trading luxury watches. It facilitates buying, selling, and servicing of timepieces through its in-house certified watchmaking atelier. The platform offers brand new models alongside pre-owned and vintage pieces, all inspected for quality and authenticity.

CEVEC Pharmaceuticals GmbH is a biopharmaceutical company based in Cologne, Germany, specializing in the production of therapeutic proteins and monoclonal antibodies using a unique human cell-based expression system. Founded in 2001, CEVEC has developed the CAP-GO platform, which allows for the efficient production of complex, glycosylated proteins that are challenging to express using conventional cell lines. This platform includes optimized expression vectors, serum- and animal component-free cell line generation, and stable pool generation for recombinant proteins. Additionally, CEVEC offers the CAP-GT platform, facilitating large-scale production of gene therapy vectors, including Lentiviral, Adenoviral, and AAV types. The company also provides contract manufacturing services and has established a strategic collaboration with BioLamina AB, enhancing its capabilities in the biopharmaceutical sector.

PRECIRE Technologies is a leader in speech analysis technology, established in 2012. The company has developed the PRECIRE® platform, which decodes written and spoken language to provide insights into the interactions between personality and behavior. By transforming text into numerous features and comparing them against extensive, psychologically validated reference data sets, the platform delivers precise assessments of communicative effects, emotions, personality traits, and linguistic competence. This technology offers valuable insights into employees, customers, applicants, and other conversational partners, facilitating more intelligent, individualized, and efficient interactions.

Rigontec GmbH is a biopharmaceutical company based in Planegg, Germany, focused on developing RNA-based immunotherapeutics for cancer and viral diseases. Founded in 2014, the company is recognized for its innovative approach to immuno-oncology, particularly through its lead compound ImOl100. This compound acts as a stimulator of the immune receptor retinoic acid-inducible gene I (RIG-I), which detects viral RNA and promotes immune responses. ImOl100 serves as a minimal mimic of naturally occurring 3pRNA, a motif commonly found in viral RNAs, and aims to overcome the limitations associated with traditional cancer vaccines and checkpoint inhibitors. As of October 2017, Rigontec operates as a subsidiary of Merck & Co., enhancing its capabilities in the development of effective therapeutic options for patients.

Mapudo is an independent online marketplace focused on the metals supply industry, specializing in the trading and processing of steel. By creating a standardized platform for product searches, Mapudo connects buyers and sellers of various metals, facilitating the procurement process for both parties. This innovative approach simplifies the buying and selling of steel products, enabling dealers and buyers to conduct transactions online efficiently. Mapudo aims to streamline the metals supply chain, ultimately saving time and money for all participants in the market.

Protagen is a precision medicine company that specializes in drug development and patient management, particularly in the fields of autoimmune diseases and immuno-oncology. The company focuses on immuno-profiling and the discovery of novel autoantibody signatures, utilizing its SeroTag® technology to identify biomarkers that address challenges in the development of cancer immunotherapies and treatments for autoimmune conditions. Protagen is recognized for its expertise in patient stratification, having created disease-specific NavigAID panels that assess individual patients' autoimmune conditions and immune statuses. This tailored approach enables the development of more targeted therapies for various autoimmune diseases, including systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and Sjögren’s syndrome. Additionally, Protagen's biomarker discovery platform aids in the detection of autoantibodies in patients undergoing cancer immunotherapy, which helps predict treatment responses and supports informed therapeutic decisions.

Vimecon GmbH, founded in 2005 and headquartered in Herzogenrath, Germany, specializes in the development and production of laser catheters aimed at treating heart diseases, particularly atrial fibrillation. The company also manufactures a range of products for the medical technology and biotechnology sectors, including microscopically small catheters and micro materials handling techniques that facilitate precise measurement and dosage. In addition to its product offerings, Vimecon provides advisory services to various clients in both academic and industrial research and development. Through its innovative solutions, the company aims to enhance healthcare outcomes in the treatment of cardiovascular diseases and cardiac arrhythmias.

CHRONEXT operates as a comprehensive platform for trading luxury watches. It facilitates buying, selling, and servicing of timepieces through its in-house certified watchmaking atelier. The platform offers brand new models alongside pre-owned and vintage pieces, all inspected for quality and authenticity.

Rigontec GmbH is a biopharmaceutical company based in Planegg, Germany, focused on developing RNA-based immunotherapeutics for cancer and viral diseases. Founded in 2014, the company is recognized for its innovative approach to immuno-oncology, particularly through its lead compound ImOl100. This compound acts as a stimulator of the immune receptor retinoic acid-inducible gene I (RIG-I), which detects viral RNA and promotes immune responses. ImOl100 serves as a minimal mimic of naturally occurring 3pRNA, a motif commonly found in viral RNAs, and aims to overcome the limitations associated with traditional cancer vaccines and checkpoint inhibitors. As of October 2017, Rigontec operates as a subsidiary of Merck & Co., enhancing its capabilities in the development of effective therapeutic options for patients.

AYOXXA Biosystems GmbH is a life science tools company based in Cologne, Germany, with additional offices in Singapore and Boston, Massachusetts. Founded in 2010, AYOXXA specializes in developing a proprietary technology platform for multiplexed protein analysis. This platform, which utilizes In-situ Encoded Bead-based Arrays, enables users to simultaneously measure multiple protein markers associated with various health conditions, including cancer, allergies, cardiovascular diseases, and infectious diseases. AYOXXA's innovative biochips merge biological analysis with information technology, expanding the potential applications in biomedical research. The company also offers biomarker kits to facilitate the identification and quantification of proteins and other biomolecular analytes.

CryoTherapeutics GmbH, founded in 2009 and based in Cologne, Germany, specializes in the development of a proprietary cryotherapy system aimed at treating coronary artery disease, a major cause of heart attacks. The company focuses on demonstrating the clinical benefits and ensuring the safety and efficacy of cryoenergy in the cardiovascular system. Its novel catheter system utilizes cryo energy to treat and prevent heart attacks, offering a promising approach to addressing the challenges posed by diseased coronary arteries. Through its early-stage commercialization efforts, CryoTherapeutics aims to enhance treatment options for heart surgeons and improve patient outcomes in cardiovascular health.

evocatal develops and produces enzymes and fine chemicals for the chemical and pharmaceutical industries. We offer a catalog of enzymes (evozymes) as well as and tailor-made biocatalysts for specific industrial applications. Our biocatalysts are applied in various consumer goods industries, including the production and refinement of textiles, adhesives, detergents, nutrition and cosmetics. Our customers regard evocatal as a premium provider of high quality chiral building blocks (evochemicals): from a few grams to several tons. At evocatal we have also continued to focus on providing efficient biocatalytic processes as a service (evoservices). Do you need a biocatalyst for a very specific application? Contact us!

Founded in 2010, Saperatec specializes in recycling technologies. Its proprietary process physically and chemically separates bonded and coated materials, transforming multi-layer waste into valuable secondary raw materials.

Founded in 2009, GreenPocket is a leading European specialist in energy management software. It provides innovative solutions for utilities and corporate customers worldwide, leveraging AI, machine learning, and data science to derive value from smart meter data. The company's intuitive platforms enable residential customers and businesses to monitor and reduce their energy consumption, contributing to the digitalization of the energy industry and a sustainable future.

Azeti GmbH, based in Berlin, Germany, is a provider of Internet of Things (IoT) solutions that focus on monitoring and managing technology infrastructures. Founded in 2006, the company offers a range of products, including SONARPLEX, which delivers real-time information for logistics companies, allowing for the monitoring of fuel consumption, vehicle condition, and driver activity. Their SonarWise product connects remote cell sites to a company’s network operations center, enabling real-time oversight of technical equipment and energy usage. Additionally, Azeti provides applications such as SONARMANAGER for centralized management and the azeti Lab app for mobile access. Their solutions cater to various sectors, including telecommunications, data centers, and transportation, facilitating applications like condition monitoring and predictive maintenance. With a focus on customer needs and agile project execution, Azeti serves partners, distributors, and system integrators globally. As of July 2020, Azeti operates as a subsidiary of Aurubis AG, enhancing its capabilities in delivering IoT solutions.

CEVEC Pharmaceuticals GmbH is a biopharmaceutical company based in Cologne, Germany, specializing in the production of therapeutic proteins and monoclonal antibodies using a unique human cell-based expression system. Founded in 2001, CEVEC has developed the CAP-GO platform, which allows for the efficient production of complex, glycosylated proteins that are challenging to express using conventional cell lines. This platform includes optimized expression vectors, serum- and animal component-free cell line generation, and stable pool generation for recombinant proteins. Additionally, CEVEC offers the CAP-GT platform, facilitating large-scale production of gene therapy vectors, including Lentiviral, Adenoviral, and AAV types. The company also provides contract manufacturing services and has established a strategic collaboration with BioLamina AB, enhancing its capabilities in the biopharmaceutical sector.

NonWoTecc GmbH was founded with the financial support of High-Tech Gründerfond (HTGF) and Rheinland Venture Capital Fond (RVC) in February of 2007. The goal was to develop a newly designed vascular prosthesis with improved biocompatible and bio-stable properties. NonWoTecc GmbH was one of only seven companies which received a commitment for financial support from HTGF in 2006.

Vimecon GmbH, founded in 2005 and headquartered in Herzogenrath, Germany, specializes in the development and production of laser catheters aimed at treating heart diseases, particularly atrial fibrillation. The company also manufactures a range of products for the medical technology and biotechnology sectors, including microscopically small catheters and micro materials handling techniques that facilitate precise measurement and dosage. In addition to its product offerings, Vimecon provides advisory services to various clients in both academic and industrial research and development. Through its innovative solutions, the company aims to enhance healthcare outcomes in the treatment of cardiovascular diseases and cardiac arrhythmias.

simfy GmbH operates as an online music platform. The company allows to share and store music online, as well as to listen instantly to specific tracks or albums via true on demand streaming. simfy GmbH was founded in 2006 and is based in Cologne, Germany.

Fashionette AG operates a data‑driven online retail platform that connects European consumers with a wide range of designer fashion accessories, including handbags, shoes, sunglasses, watches, jewelry, and pre‑loved pieces. Founded in 2008, the company is headquartered in Düsseldorf and offers a personalized shopping experience through its extensive selection of products.

Protagen is a precision medicine company that specializes in drug development and patient management, particularly in the fields of autoimmune diseases and immuno-oncology. The company focuses on immuno-profiling and the discovery of novel autoantibody signatures, utilizing its SeroTag® technology to identify biomarkers that address challenges in the development of cancer immunotherapies and treatments for autoimmune conditions. Protagen is recognized for its expertise in patient stratification, having created disease-specific NavigAID panels that assess individual patients' autoimmune conditions and immune statuses. This tailored approach enables the development of more targeted therapies for various autoimmune diseases, including systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and Sjögren’s syndrome. Additionally, Protagen's biomarker discovery platform aids in the detection of autoantibodies in patients undergoing cancer immunotherapy, which helps predict treatment responses and supports informed therapeutic decisions.

simfy GmbH operates as an online music platform. The company allows to share and store music online, as well as to listen instantly to specific tracks or albums via true on demand streaming. simfy GmbH was founded in 2006 and is based in Cologne, Germany.

Direvo Industrial Biotechnology GmbH is a privately owned company based in Cologne, Germany, specializing in the development and marketing of biology-based products and processes for non-pharmaceutical applications. Founded in 2008, the company utilizes its expertise in enzymes, microbes, and process optimization to create bio-based solutions across various sectors, including clean energy, clean chemistry, and biomass conversion. Direvo offers a range of innovative platforms, such as the BluZy portfolio, designed for the grain ethanol industry, which includes products that enhance the nutritional value of bio-ethanol by-products and improve process efficiency in ethanol production. Additionally, the company provides the BluServ platform, focused on automated high-throughput screening for protein and strain engineering, and the BluCon technology platform, which converts non-food feedstocks into carbohydrates for fuel and chemical production. Direvo collaborates with global leaders in the industry to deliver customized solutions tailored to specific market needs.

CEVEC Pharmaceuticals GmbH is a biopharmaceutical company based in Cologne, Germany, specializing in the production of therapeutic proteins and monoclonal antibodies using a unique human cell-based expression system. Founded in 2001, CEVEC has developed the CAP-GO platform, which allows for the efficient production of complex, glycosylated proteins that are challenging to express using conventional cell lines. This platform includes optimized expression vectors, serum- and animal component-free cell line generation, and stable pool generation for recombinant proteins. Additionally, CEVEC offers the CAP-GT platform, facilitating large-scale production of gene therapy vectors, including Lentiviral, Adenoviral, and AAV types. The company also provides contract manufacturing services and has established a strategic collaboration with BioLamina AB, enhancing its capabilities in the biopharmaceutical sector.

Direvo Industrial Biotechnology GmbH is a privately owned company based in Cologne, Germany, specializing in the development and marketing of biology-based products and processes for non-pharmaceutical applications. Founded in 2008, the company utilizes its expertise in enzymes, microbes, and process optimization to create bio-based solutions across various sectors, including clean energy, clean chemistry, and biomass conversion. Direvo offers a range of innovative platforms, such as the BluZy portfolio, designed for the grain ethanol industry, which includes products that enhance the nutritional value of bio-ethanol by-products and improve process efficiency in ethanol production. Additionally, the company provides the BluServ platform, focused on automated high-throughput screening for protein and strain engineering, and the BluCon technology platform, which converts non-food feedstocks into carbohydrates for fuel and chemical production. Direvo collaborates with global leaders in the industry to deliver customized solutions tailored to specific market needs.

Audimark GmbH, headquartered in Aachen, Germany, specializes in marketing services tailored to web radio stations. As a market leader, the company offers promotional solutions designed to enhance the visibility and reach of its clients' online audio platforms.