Pressure BioSciences
Pressure BioSciences, Inc. (PBI), a life sciences company, engages in the research, development, and commercialization of sample preparation system. It focuses on the development of a platform technology, called pressure cycling technology (PCT) that uses cycles of hydrostatic pressure between ambient and ultra-high levels to control bio-molecular interactions. The company offers Barocycler instrument and an internally developed disposable PULSE (Pressure Used to Lyse Samples for Extraction) Tubes, which together make up the PCT sample preparation system. It holds 13 U.S. and 5 foreign patents covering multiple applications of PCT in the life sciences field. PCT has applications in a various life sciences areas, including sample preparation for genomic, proteomic, and small molecule studies; control of chemical (enzymatic) reactions; protein purification; pathogen inactivation; immunodiagnostics; DNA sequencing; and food safety. PBI's customers include academic laboratories, government agencies, and biotechnology companies. The company was founded in 1978. It was formerly known as Boston Biomedica, Inc. and changed its name to Pressure BioSciences, Inc. in 2004. Pressure BioSciences is based in South Easton, Massachusetts.
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BaroFold is a biopharmaceutical company dedicated to the development of innovative protein therapeutics, particularly targeting immunology conditions such as Multiple Sclerosis, Rheumatoid Arthritis, and Asthma. The company utilizes its proprietary PreEMT™ technology, which employs high pressure folding to enhance the tolerability, efficacy, and safety of protein biologics. This technology allows for the disaggregation and controlled refolding of proteins, ensuring a high fidelity of native structure. By leveraging this state-of-the-art approach, BaroFold aims to support biopharmaceutical companies, research institutions, and government agencies in creating novel therapeutics, accelerating development processes, and managing the life cycles of protein-based treatments.
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