Terumo Corporation

Diabeloop is a medical device company based in Grenoble, France, focused on innovating diabetes treatment through advanced technology. Founded in 2015, the company specializes in developing an AI-based closed-loop system that automates insulin delivery for individuals with type 1 diabetes. This system includes a blood sugar monitoring device that combines a glucose sensor, an insulin pump, and a smartphone application featuring an embedded algorithm. By continuously measuring glucose levels and delivering the appropriate insulin dosage, Diabeloop aims to reduce the mental burden on patients, allowing them to manage their condition more effectively and live their lives with greater ease.

Diabeloop is a medical device company based in Grenoble, France, focused on innovating diabetes treatment through advanced technology. Founded in 2015, the company specializes in developing an AI-based closed-loop system that automates insulin delivery for individuals with type 1 diabetes. This system includes a blood sugar monitoring device that combines a glucose sensor, an insulin pump, and a smartphone application featuring an embedded algorithm. By continuously measuring glucose levels and delivering the appropriate insulin dosage, Diabeloop aims to reduce the mental burden on patients, allowing them to manage their condition more effectively and live their lives with greater ease.

Orchestra BioMed is a biomedical innovation company based in New Hope, Pennsylvania, founded in 2017. The company specializes in developing high-impact therapeutic solutions for major medical conditions, with a primary focus on cardiovascular diseases, which are responsible for approximately 31% of global deaths annually. Orchestra BioMed's business model involves strategic partnerships with medical device companies to accelerate the commercialization of its products. Its key product candidates include BackBeat Cardiac Neuromodulation Therapy for hypertension and Virtue Sirolimus AngioInfusionBalloon for atherosclerotic artery disease.

Health Outcomes Sciences LLC specializes in providing information technology solutions aimed at enhancing the quality of healthcare delivery. Founded in 2005 and based in Overland Park, Kansas, the company focuses on translating advances in clinical research into practical decision-support products and services for healthcare providers and organizations. Its ePRISM platform allows for the creation and deployment of evidence-based predictive models as web-based tools, facilitating personalized educational materials and informed consent documents. This platform is designed to assist in various clinical applications, including clinical decision support, shared medical decision-making, and patient education. Additionally, Health Outcomes Sciences offers readmission models that estimate risks associated with conditions such as heart failure and pneumonia, thereby aiding in the reduction of hospital readmission rates. By leveraging predictive analytics, the company enables clinicians to better understand the relationships between clinical variables and patient outcomes, ultimately improving individualized patient care.

Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, the company focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. Cuorips is involved in the manufacturing and sales of cellular and tissue-based products, as well as providing contract development and manufacturing services. The company aims to advance medical treatments through innovative cell products and therapies.

Quirem Medical B.V. is a medical device company based in Diepenveen, the Netherlands, founded in 2013. The company specializes in developing microspheres for Selective Internal Radiation Therapy (SIRT), specifically targeting liver malignancies. Its flagship product, QuiremSpheres, utilizes radioactive holmium-166 microspheres for radioembolization treatment, which allows for imaging and quantification to enhance patient selection, treatment planning, and verification. Quirem Medical aims to optimize treatment outcomes for patients with unresectable liver cancer by providing a complete solution that includes QuiremScout, QuiremSpheres, and dosimetry software known as Q-Suite. As of July 2020, Quirem Medical operates as a subsidiary of Terumo Corporation.

Orchestra BioMed is a biomedical innovation company based in New Hope, Pennsylvania, founded in 2017. The company specializes in developing high-impact therapeutic solutions for major medical conditions, with a primary focus on cardiovascular diseases, which are responsible for approximately 31% of global deaths annually. Orchestra BioMed's business model involves strategic partnerships with medical device companies to accelerate the commercialization of its products. Its key product candidates include BackBeat Cardiac Neuromodulation Therapy for hypertension and Virtue Sirolimus AngioInfusionBalloon for atherosclerotic artery disease.

Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, the company focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. Cuorips is involved in the manufacturing and sales of cellular and tissue-based products, as well as providing contract development and manufacturing services. The company aims to advance medical treatments through innovative cell products and therapies.

Vascutek is a designer and manufacturer specializing in products for vascular and cardiovascular clinicians. With over 35 years of experience, the company has developed a diverse range of products, including sealed woven and knitted polyester grafts for peripheral, abdominal, and cardiothoracic surgery, as well as ePTFE grafts and a custom AAA stent graft system. Vascutek focuses on addressing the needs of healthcare professionals in treating cardiovascular diseases. As a subsidiary of the Terumo Corporation of Japan, a leading global medical device company, Vascutek benefits from a robust support network and a commitment to innovation in medical technology.

ReThink Medical, Inc. is a medical device and digital health company based in San Francisco, California, specializing in the development of a wrist-worn monitoring device. Founded in 2010 and now a subsidiary of Terumo Corporation, ReThink Medical focuses on predicting and preventing heart failure hospitalizations through continuous physiological monitoring and advanced machine learning algorithms. Its flagship product, CorBand™, is designed to detect and notify users of worsening heart conditions weeks in advance, even before noticeable symptoms emerge. This proactive approach emphasizes compliance, simplicity, and accuracy, aiming to improve quality of life for patients while significantly reducing healthcare costs. The device monitors key indicators such as heartbeat rate and fluid status, enabling timely intervention and management of heart-related disorders.

Bolton Medical, Inc., established in 1998 and headquartered in Sunrise, Florida, specializes in developing endovascular solutions for aortic treatment. The company's primary product is RelayPlus, a thoracic stent-graft featuring a dual sheath delivery system, designed for precise aortic navigation and placement. Bolton Medical also focuses on developing abdominal stent-graft solutions. It operates as a subsidiary of Vascutek Ltd. and serves customers in North America through its representative network.

CaridianBCT is a global provider of technology, products and services in automated blood collection, therapeutic systems, whole blood processes and pathogen reduction technologies.