Terumo Corporation

Diabeloop is a medical device company based in Grenoble, France, specializing in innovative solutions for diabetes management. Founded in 2015, the company focuses on developing a closed-loop system that automates insulin delivery for individuals with type 1 diabetes. Its AI-based blood sugar monitoring device integrates a sensor that continuously measures glucose levels, a pump that administers insulin, and a smartphone application that connects these components through an embedded algorithm. This technology aims to enhance the treatment experience by reducing the mental burden on patients, allowing them to manage their condition more effortlessly and live their lives with greater freedom.

Diabeloop is a medical device company based in Grenoble, France, specializing in innovative solutions for diabetes management. Founded in 2015, the company focuses on developing a closed-loop system that automates insulin delivery for individuals with type 1 diabetes. Its AI-based blood sugar monitoring device integrates a sensor that continuously measures glucose levels, a pump that administers insulin, and a smartphone application that connects these components through an embedded algorithm. This technology aims to enhance the treatment experience by reducing the mental burden on patients, allowing them to manage their condition more effortlessly and live their lives with greater freedom.

Orchestra BioMed is a biomedical innovation company based in New Hope, Pennsylvania, founded in 2017. The company specializes in developing high-impact therapeutic solutions for major medical conditions, with a primary focus on cardiovascular diseases, which are responsible for approximately 31% of global deaths annually. Orchestra BioMed's business model involves strategic partnerships with medical device companies to accelerate the commercialization of its products. Its key product candidates include BackBeat Cardiac Neuromodulation Therapy for hypertension and Virtue Sirolimus AngioInfusionBalloon for atherosclerotic artery disease.

Health Outcomes Sciences LLC, established in 2005 and based in Overland Park, Kansas, specializes in providing information technology solutions to enhance healthcare delivery. The company focuses on translating advancements in clinical research into practical, evidence-based tools for physicians, patients, and healthcare organizations. Its flagship product is the ePRISM platform, which facilitates the creation of predictive models as Web-based tools and XML Web services. These models can be updated in real-time and are used across various applications such as clinical decision support, shared medical decision-making, patient education, and personalized educational materials. Additionally, Health Outcomes Sciences offers readmission models to estimate risk-standardized days that cause readmission rates for patients admitted with specific conditions like PCI, acute myocardial infarction, COPD, heart failure, and pneumonia. The company's interdisciplinary team comprises physicians, outcomes researchers, and IT experts who prioritize creating intuitive, responsive user interfaces that integrate seamlessly into clinical workflows.

Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, it focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. The company offers manufacturing and sales of cellular and tissue-based products, along with contract development and manufacturing services. Cuorips aims to advance medical treatments through innovation in cell processing and therapeutic applications.

Quirem Medical B.V. is a medical device company based in Diepenveen, the Netherlands, that specializes in developing advanced microspheres for the targeted treatment of liver malignancies. Founded in 2013, the company focuses on Selective Internal Radiation Therapy (SIRT) using its proprietary Holmium-166 microspheres, known as QuiremSpheres. This innovative treatment allows for the radioembolization of liver cancer, combining therapeutic effects with imaging capabilities that enhance patient selection, treatment planning, and verification. Quirem Medical offers a comprehensive SIRT solution, including its QuiremScout diagnostic tool and the Q-Suite dosimetry software, which supports healthcare professionals in delivering personalized treatment options for patients with unresectable liver tumors. As of July 2020, Quirem Medical operates as a subsidiary of Terumo Corporation.

Orchestra BioMed is a biomedical innovation company based in New Hope, Pennsylvania, founded in 2017. The company specializes in developing high-impact therapeutic solutions for major medical conditions, with a primary focus on cardiovascular diseases, which are responsible for approximately 31% of global deaths annually. Orchestra BioMed's business model involves strategic partnerships with medical device companies to accelerate the commercialization of its products. Its key product candidates include BackBeat Cardiac Neuromodulation Therapy for hypertension and Virtue Sirolimus AngioInfusionBalloon for atherosclerotic artery disease.

Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, it focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. The company offers manufacturing and sales of cellular and tissue-based products, along with contract development and manufacturing services. Cuorips aims to advance medical treatments through innovation in cell processing and therapeutic applications.

Vascutek is a company specializing in the design and manufacture of products for vascular and cardiovascular clinicians. With over three decades of experience, Vascutek has developed a broad portfolio of innovative technologies, including sealed woven and knitted polyester grafts for various surgical procedures, ePTFE grafts, and custom AAA stent graft systems. The company is a subsidiary of Terumo Corporation, a leading global medical device company based in Japan with a workforce exceeding 21,000 employees worldwide.

ReThink Medical, Inc. is a medical device and digital health company based in San Francisco, California, founded in 2010. The company specializes in the development of wrist-worn monitoring devices designed to predict and prevent hospitalizations due to heart failure. Their flagship product, CorBand™, utilizes advanced algorithms and artificial intelligence to continuously monitor physiological indicators such as heart rate and fluid status. This technology enables early detection of worsening heart conditions, potentially weeks in advance of noticeable symptoms. By focusing on compliance and ease of use, ReThink Medical aims to provide proactive management of heart failure patients, improving their quality of life while reducing healthcare costs associated with emergency interventions. In 2020, ReThink Medical became a subsidiary of Terumo Corporation.

Bolton Medical, Inc., established in 1998 and headquartered in Sunrise, Florida, specializes in developing endovascular solutions for aortic treatment. The company's primary product is RelayPlus, a thoracic stent-graft featuring a dual sheath delivery system, designed for precise aortic navigation and placement. Bolton Medical also focuses on developing abdominal stent-graft solutions. It operates as a subsidiary of Vascutek Ltd. and serves customers in North America through its representative network.

CaridianBCT is a global provider of technology, products and services in automated blood collection, therapeutic systems, whole blood processes and pathogen reduction technologies.