Alexandria

Alexandria Venture Investments, LLC is a venture capital firm established in 1996 and headquartered in Pasadena, California. As the strategic investment arm of Alexandria Real Estate Equities, it focuses on providing capital to seed, early-stage, and growth-stage companies within the healthcare sector. The firm emphasizes investments in biopharma, diagnostics, life sciences, research tools, agrifoodtech, and agtech. Alexandria Venture Investments aims to support innovative entities developing breakthrough technologies and therapies, leveraging its extensive industry knowledge and relationships with leading investors. Its approach is characterized by a commitment to fostering innovation and entrepreneurship in the life sciences and technology sectors.

Thomas Andrews

Co-President & Regional Market Director

John Cox

Senior Vice President - Regional Market Director

John H. Cunningham

Executive Vice President - Regional Market Director

Larry Diamond

Co-Chief Operating Officer & Regional Market Director

Joel Marcus

Head of Alexandria Venture Investments

Todd Miller

Senior Vice President -Regional Leasing & Asset Services

Hunter Reed

Senior Associate

Daniel J. Ryan

Co-CIO

Oliver Sherrill

Senior Vice President - Regional Market Director

Past deals in North Carolina

Ten63 Therapeutics

Series A in 2023
Ten63 Therapeutics is a venture-backed startup developing durable therapeutics against some of the most lethal diseases. It combines low-residual, ML-based computational chemistry and mathematically guaranteed, superlinear search algorithms to find optimized drug candidates. The company's platform, COPPER, leverages its proprietary AI and state-of-the-art physical models to explore an unprecedentedly large chemical space, allowing them to discover new therapeutics to targets previously believed undruggable.

Tavros Therapeutics

Seed Round in 2022
Tavros Therapeutics is a biotechnology company founded in 2019 and based in Durham, North Carolina. The company focuses on discovering and developing therapies for cancer, aiming to improve oncological treatment outcomes. Tavros Therapeutics is dedicated to identifying vulnerabilities within tumors, which allows for the targeted application of specific drugs in conjunction with optimal combinations. This approach is intended to enhance the effectiveness of cancer treatments and increase the potential for patient cures.

Harpe Bio

Series A in 2022
Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. The company was founded in 2020 by Chad Brommer and is headquartered in Raleigh, North Carolina, United States.

Avalo

Convertible Note in 2022
Avalo is a biotech company generating crop resilience through gene discovery and control for a healthier and fuller world. The company uses interpretable machine learning to identify genes in plants at a much faster pace to help develop better crops.

GeneCentric

Series B in 2021
GeneCentric Diagnostics is engaged in the development and commercialization of molecular diagnostic tests aimed at assisting oncologists and patients in cancer treatment. The company has established two primary platform technologies: The Lung Subtype Platform (LSP), which classifies lung cancer patients into specific subtypes to guide therapeutic choices, and the Hypoxia Signature, designed to identify patients likely to benefit from anti-angiogenesis therapies. The LSP has been licensed to Laboratory Corporation of America Holdings and is available as HistoPlusSM: Lung Cancer through its Integrated Oncology division. GeneCentric's innovative partnership model facilitates the translation of significant cancer research into diagnostics that are clinically adopted by pathologists and clinicians. Incorporated in 2011 and located in Durham, North Carolina, GeneCentric aims to enhance treatment outcomes by enabling more precise targeting of therapeutic compounds based on tumor biology.

Soli Organic

Venture Round in 2021
Soli Organic is a company that specializes in the cultivation, packing, and shipping of fresh organic culinary herbs. Founded in 1989 and headquartered in Harrisonburg, Virginia, it operates a production facility in Jefferson, Georgia. Soli Organic offers a diverse range of products, including various herbs such as basil, cilantro, dill, mint, and thyme, as well as herb blends and microgreens. The company provides a year-round supply of these organic herbs to grocery stores, enabling consumers to enjoy locally sourced, flavorful ingredients throughout the year. In addition to its agricultural operations, Soli Organic also offers refrigerated transportation services to ensure efficient delivery. It primarily serves retailers across several states in the southeastern United States, including Georgia, Florida, and North Carolina.

Humacyte

Post in 2021
Humacyte, Inc. is a medical research and development company headquartered in Morrisville, North Carolina, established in 2004. The company specializes in creating human tissue-based products aimed at regenerative medicine and vascular surgery. Its core technology involves the design of acellular extracellular matrices derived from banked vascular smooth muscle cells, which are decellularized to minimize the risk of rejection. These innovations are utilized to produce tissue-engineered grafts for patients requiring vascular repair or replacement, positioning Humacyte as a key player in addressing vascular diseases and enhancing surgical outcomes.

Advanced Animal Diagnostics

Venture Round in 2021
Advanced Animal Diagnostics, Inc. commercializes proprietary technology for the diagnosis of farm-animal diseases. It uses an animal's own immune response to detect and stage infections to improve the quality of life for producers, processors, animals, and consumers. The company offers QuickSmear, a rapid differential slide to speed and simplify production animal research using differential cell counts; and SCC+ System for early detection of mastitis. Advanced Animal Diagnostics was founded in 2001 and is based in Durham, North Carolina.

Genetron Health

Series D in 2019
Genetron Health is a world-leading expert in precision medicine.They are committed to developing health management products that cover all elements of full-cycle cancer clinical treatment (including risk assessment, early screening, molecular pathology diagnosis, medication guidance and prognosis monitoring) and effectively applying genomic data to assist medical experts and research scientists. Additionally, they provide cancer patients and high-risk and healthy individuals with reliable molecular clinical services and professional cancer genetic risk assessment.In just three years, Genetron Health has built global genomics sequencing and bioinformatics platforms, established two research and development centers in both North Carolina, U.S., and Beijing, China, and set up clinical laboratories in Beijing, Shanghai, Hangzhou and Chongqing of over 10,000 square meters.In the future, Genetron Health will spread its sales network throughout China with professional marketing, product management, medical experts and scientific research teams, and will provide service for Chinese and global cancer patients with its strong foundation in cancer genomics and efficient clinical translation.

Greenlight Biosciences

Venture Round in 2019
GreenLight Biosciences is a biotechnology company that specializes in RNA-based solutions for agricultural and pharmaceutical applications. Founded in 2008 and headquartered in Medford, Massachusetts, with an additional location in North Carolina, the company utilizes its Unconstrained Metabolism technology platform to convert renewable substrates into valuable chemicals and fuels. This platform allows for significant flexibility and control in the production process. GreenLight is also focused on developing RNA products aimed at improving crop management, plant protection, and animal health, while advancing vaccine development and pandemic preparedness. In addition to these applications, the company is working on mRNA-based vaccine candidates targeting seasonal and pandemic influenza, as well as other emerging viruses, to enhance public health. Through its innovations, GreenLight aims to provide sustainable solutions that contribute to global food security and health.

Ribometrix

Series A in 2018
Ribometrix is a platform therapeutics company that discovers small molecule drugs that target functional 3D RNA structures to treat human diseases. Our scientific offices are located in the newly renovated Biolabs Space in Durham, with offices in Chapel Hill and Boston.

StrideBio

Series A in 2018
StrideBio, Inc. creates and develops adeno-associated viral (AAV) vector technologies and therapeutics that enables gene addition, gene silencing, and gene editing modalities for rare diseases. The company develops a proprietary platform by combining structural information with accelerated evolution to create novel AAV capsids that can evade neutralizing antibodies. The company was founded in 2015 and is based in Durham, North Carolina.

Ribometrix

Seed Round in 2017
Ribometrix is a platform therapeutics company that discovers small molecule drugs that target functional 3D RNA structures to treat human diseases. Our scientific offices are located in the newly renovated Biolabs Space in Durham, with offices in Chapel Hill and Boston.

Boragen

Series A in 2017
Boragen Inc. is a biotechnology company based in Durham, North Carolina, that specializes in designing and developing multifunctional small molecule boron solutions for applications in crop protection, animal health, and human health. Founded in 2015, the company focuses on creating next-generation fungicides through its synthetic chemistry platforms, which aim to promote sustainable farming practices. Boragen's product pipeline includes BAG8, a boron-based multisite fungicide, and BN2266, which targets mRNA processing as a crop protection fungicide. Additionally, the company is developing a dual-function nematicide-fungicide designed for root protection and endo-parasiticides that address resistance challenges. Through its innovative approach, Boragen seeks to enhance agricultural efficiency while minimizing chemical usage.