Angelini Ventures

Biovitae focuses on patent development in infection control and prevention, translating scientific discoveries into practical applications to improve human health and quality of life. The company develops sanitation and lighting solutions for home environments, including NO-UV light bulbs and a combined LED and photocatalysis technology that reduces bacterial load by neutralizing bacteria, viruses, molds, fungi, and spores.

Vantis offers holistic primary healthcare services focused on managing chronic diseases. It combines digital health services with a network of physical healthcare facilities, aiming to enhance health outcomes through continuous care and improved patient accessibility.

Vantis Vascular is a medical device company that specializes in developing innovative solutions for vascular interventions, particularly in complex and calcified arteries. The company focuses on creating tools that enhance the delivery and efficiency of therapeutic treatments, addressing the challenges faced by interventionalists. Its primary product is a guide extension designed to facilitate the navigation of catheter tubes through arteries during medical procedures. This device aids in the delivery of coronary stents to patients, thereby simplifying cardiac interventions and improving patient outcomes.

Nobi is a smart lamp that ensures help can be provided in a flash in the event of a fall. It recognizes a fall, and it will notify a family member, contacts, or a specialized emergency call center. The lamp will then connect to that person to reassure them that help is on the way. If necessary, it can even unlock the smart lock on the front door.

Founded in 2020, NEUmiRNA focuses on achieving transformative disease modification for neurological conditions.

Aptadir Therapeutics is a biotechnology company focused on developing novel treatments for diseases associated with abnormal DNA methylation. The company's approach involves using RNA therapeutics to inhibit the function of DNMT1, an enzyme responsible for adding methyl groups to DNA. Specifically, Aptadir is working on a treatment for Myelodysplastic Neoplasms, a group of conditions that affect the blood and bone marrow.

Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates engineered viral vector vaccines for cancer treatment. The company's innovative platform leverages a portfolio of modified viral vectors, specifically designed for the efficient expression of long strings of tumor neoantigens. This approach is complemented by a toolkit that facilitates the induction of robust antitumor T-cell responses, effectively enhancing cancer-specific cellular immunity in patients. Through its research and development efforts, Nouscom aims to improve cancer treatment outcomes by harnessing the body's immune system to target and combat cancer cells.

Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.

Cour Pharmaceuticals Development Co Inc, founded in 2012 and based in Elmhurst, Illinois, operates in the pharmaceutical sector with a focus on developing an immune-modifying platform. This platform aims to achieve antigen-specific tolerance for immune-mediated diseases and provides non-biological therapeutics for conditions such as acute inflammation, autoimmunity, and allergies. The company is engaged in the pharmaceutical development of products related to immunology, pathology, and cardiovascular health, enabling the treatment of various conditions, including encephalitis syndromes, autoimmune disorders, infections, and heart attacks.

Noctrix Health, Inc. is an early-stage medical device company founded in 2018 and based in Menlo Park, California. The company specializes in developing therapeutic wearable devices aimed at treating chronic neurological and sleep disorders, particularly focusing on conditions such as restless leg syndrome. Noctrix Health's innovative devices leverage neural circuitry to alleviate symptoms, promoting undisturbed sleep and allowing patients to manage their chronic medical conditions more effectively.

Freya Biosciences is a clinical-stage company specializing in women's health. It develops microbial immunotherapies, focusing on unmet needs across various indications.

Biovitae focuses on patent development in infection control and prevention, translating scientific discoveries into practical applications to improve human health and quality of life. The company develops sanitation and lighting solutions for home environments, including NO-UV light bulbs and a combined LED and photocatalysis technology that reduces bacterial load by neutralizing bacteria, viruses, molds, fungi, and spores.

Cadence Neuroscience develops implantable medical device therapies for epilepsy, central pain, and other neurological disorders. Founded in 2017 and based in Redmond, Washington, the company pursues core technology developed at Mayo Clinic that is being evaluated clinically. The device detects brain signals and delivers electrical stimulation to modulate neural circuits, enabling personalized brain stimulation to improve seizure control relative to existing protocols.

Serenis Health is a provider of mental health services that focuses on making therapy more accessible to individuals. The company offers video-based psychotherapy, coaching, and psychological support courses, leveraging the internet to enhance access to mental health care. Serenis distinguishes itself by functioning as a medical center, ensuring that its course quality meets the stringent standards required of a polyclinic. Patients begin their journey by completing an online scientific questionnaire, which helps connect them to qualified psychotherapists for personalized support through video calls. By utilizing data and digital tools, Serenis aims to improve the efficacy of its therapeutic offerings.

Therini Bio is a biotechnology company focused on developing fibrin-targeting therapies for treating inflammatory neurological and retinal diseases. Its therapeutics are based on unique insights into the role of fibrin in driving chronic innate immune activation, addressing high unmet needs in various diseases.

Nuevocor is a preclinical-stage biopharmaceutical company dedicated to developing gene therapy-based treatments aimed at restoring cardiac function in hearts affected by disease. The company specializes in addressing genetic cardiomyopathies, which are characterized by abnormal mechanobiology. By focusing on modulating mechanical force transduction, Nuevocor seeks to provide innovative solutions that enable healthcare professionals to improve cardiac function in patients suffering from these conditions.