Angelini Ventures

Biovitae is a company dedicated to advancing infection control and prevention through innovative technology. It specializes in developing sanitation and lighting systems designed to improve air quality and surface cleanliness in residential environments. The company’s products utilize NO-UV light bulbs and a combination of LED and photocatalysis technology to effectively reduce bacterial loads, thereby enhancing the overall health and quality of life for users. By focusing on the translation of scientific discoveries into practical applications, Biovitae aims to address critical health challenges related to sanitation and environmental safety.

Vantis is a healthcare technology company that offers an app designed to help users manage their heart health holistically at home. The app guides users in accurately measuring blood pressure, adhering to medication schedules, adopting heart-healthy nutrition, regular exercise, and relaxation techniques. It also incorporates European guidelines for heart disease treatment, enabling users to implement these standards directly into their daily routines. Vantis' approach aims to empower individuals to maintain their health and strengthen their hearts independently while providing continuous care support.

Vantis Vascular is a medical device company that specializes in developing innovative solutions for vascular interventions, particularly in complex and calcified arteries. The company focuses on creating tools that enhance the delivery and efficiency of therapeutic treatments, addressing the challenges faced by interventionalists. Its primary product is a guide extension designed to facilitate the navigation of catheter tubes through arteries during medical procedures. This device aids in the delivery of coronary stents to patients, thereby simplifying cardiac interventions and improving patient outcomes.

Nobi is a smart lamp that ensures help can be provided in a flash in the event of a fall. It recognizes a fall, and it will notify a family member, contacts, or a specialized emergency call center. The lamp will then connect to that person to reassure them that help is on the way. If necessary, it can even unlock the smart lock on the front door.

Founded in 2020, NEUmiRNA focuses on achieving transformative disease modification for neurological conditions.

Aptadir Therapeutics is a biotechnology company focused on developing novel treatments for diseases associated with abnormal DNA methylation. The company's approach involves using RNA therapeutics to inhibit the function of DNMT1, an enzyme responsible for adding methyl groups to DNA. Specifically, Aptadir is working on a treatment for Myelodysplastic Neoplasms, a group of conditions that affect the blood and bone marrow.

Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates engineered viral vector vaccines for cancer treatment. The company's innovative platform leverages a portfolio of modified viral vectors, specifically designed for the efficient expression of long strings of tumor neoantigens. This approach is complemented by a toolkit that facilitates the induction of robust antitumor T-cell responses, effectively enhancing cancer-specific cellular immunity in patients. Through its research and development efforts, Nouscom aims to improve cancer treatment outcomes by harnessing the body's immune system to target and combat cancer cells.

Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.

Cour Pharmaceuticals Development Co Inc, founded in 2012 and based in Elmhurst, Illinois, operates in the pharmaceutical sector with a focus on developing an immune-modifying platform. This platform aims to achieve antigen-specific tolerance for immune-mediated diseases and provides non-biological therapeutics for conditions such as acute inflammation, autoimmunity, and allergies. The company is engaged in the pharmaceutical development of products related to immunology, pathology, and cardiovascular health, enabling the treatment of various conditions, including encephalitis syndromes, autoimmune disorders, infections, and heart attacks.

Noctrix Health, Inc. is an early-stage medical device company founded in 2018 and based in Menlo Park, California. The company specializes in developing therapeutic wearable devices aimed at treating chronic neurological and sleep disorders, particularly focusing on conditions such as restless leg syndrome. Noctrix Health's innovative devices leverage neural circuitry to alleviate symptoms, promoting undisturbed sleep and allowing patients to manage their chronic medical conditions more effectively.

Freya Biosciences is a clinical-stage women's health company headquartered in Copenhagen and Boston, specializing in the development of microbial immunotherapies. The company focuses on addressing significant unmet medical needs across various indications by utilizing a proprietary platform to engineer and manufacture live microbes. These engineered microbes are designed to be both safe and effective for human use, facilitating the creation of innovative treatments for a range of diseases.

Biovitae is a company dedicated to advancing infection control and prevention through innovative technology. It specializes in developing sanitation and lighting systems designed to improve air quality and surface cleanliness in residential environments. The company’s products utilize NO-UV light bulbs and a combination of LED and photocatalysis technology to effectively reduce bacterial loads, thereby enhancing the overall health and quality of life for users. By focusing on the translation of scientific discoveries into practical applications, Biovitae aims to address critical health challenges related to sanitation and environmental safety.

Cadence Neuroscience, Inc. is an early-stage company founded in 2017 and headquartered in Redmond, Washington. It specializes in developing innovative medical device therapies aimed at treating epilepsy, central pain, and other neurological disorders. The company’s core technology, developed at the Mayo Clinic, is currently under clinical evaluation. Cadence Neuroscience's medical devices are designed to detect specific brain signals and deliver targeted electrical stimulation, allowing for tailored brain stimulation therapies. This approach enhances seizure control and aims to improve treatment outcomes for patients with neurological issues compared to existing protocols.

Serenis Health is a provider of mental health services that focuses on making therapy more accessible to individuals. The company offers video-based psychotherapy, coaching, and psychological support courses, leveraging the internet to enhance access to mental health care. Serenis distinguishes itself by functioning as a medical center, ensuring that its course quality meets the stringent standards required of a polyclinic. Patients begin their journey by completing an online scientific questionnaire, which helps connect them to qualified psychotherapists for personalized support through video calls. By utilizing data and digital tools, Serenis aims to improve the efficacy of its therapeutic offerings.

Therini Bio is a biotechnology company focused on developing fibrin-targeting therapies aimed at treating inflammatory neurological and retinal diseases. The company leverages groundbreaking research from the Akassoglou lab at Gladstone/UCSF, which identifies fibrin as a crucial factor in driving chronic innate immune activation associated with various diseases. By creating therapeutics that address neuroinflammation and vascular dysfunction, Therini Bio aims to provide potential treatments for conditions such as multiple sclerosis, thereby enhancing the quality of life for patients facing these challenging health issues.

Nuevocor is a preclinical-stage biopharmaceutical company dedicated to developing gene therapy-based treatments aimed at restoring cardiac function in hearts affected by disease. The company specializes in addressing genetic cardiomyopathies, which are characterized by abnormal mechanobiology. By focusing on modulating mechanical force transduction, Nuevocor seeks to provide innovative solutions that enable healthcare professionals to improve cardiac function in patients suffering from these conditions.