Angelini Ventures

Biovitae is engaged in the development of innovative sanitation and lighting systems designed to improve infection control and prevention. The company focuses on creating practical applications from scientific discoveries to enhance human health and quality of life. Its technology includes NO-UV light bulbs and a combination of LED and photocatalysis, which work together to detoxify air and surfaces within homes. By reducing bacterial load, Biovitae aims to provide safer living environments for users.

Vantis is a provider of holistic primary healthcare services focused on the management of chronic diseases. The company offers a hybrid care model that combines digital health solutions with a network of healthcare facilities to enhance health outcomes and improve access to care. Its Vantis Heart App plays a crucial role in this model by assisting users in accurately measuring blood pressure, managing medication, and adopting heart-healthy nutrition and exercise routines. By following European guidelines for heart disease treatment, the app empowers individuals to take charge of their health at home, promoting relaxation and overall well-being.

Vantis Vascular specializes in developing innovative medical devices aimed at improving vascular interventions, particularly for complex and calcified arteries. The company designs tools that enhance the delivery and efficiency of treatments, addressing significant challenges faced by interventionalists. Its primary product is a guide extension that facilitates the navigation of catheter tubes through arteries during procedures, allowing for the effective delivery of therapies such as coronary stents. This technology simplifies cardiac procedures and enhances the overall effectiveness of treatments for patients with complex lesions in coronary, pulmonary, and peripheral regions.

Nobi is a smart lamp that ensures help can be provided in a flash in the event of a fall. It recognizes a fall, and it will notify a family member, contacts, or a specialized emergency call center. The lamp will then connect to that person to reassure them that help is on the way. If necessary, it can even unlock the smart lock on the front door.

Founded in 2020, NEUmiRNA focuses on achieving transformative disease modification for neurological conditions.

Aptadir Therapeutics is developing a treatment for Myelodysplastic Neoplasms based on the capability of specific RNA therapeutics.

Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates modified viral vector vaccines for cancer treatment. The company utilizes a range of engineered viral vectors optimized for the effective expression of long strings of tumor neoantigens. Additionally, its platform includes tools designed to induce broad and potent antitumor T-cell responses, which aim to enhance cancer-specific cellular immunity in patients.

Avation Medical, Inc. is focused on developing a non-invasive closed-loop neuromodulation system designed for the at-home treatment of overactive bladder. Established in 2016 and based in Columbus, Ohio, the company is pioneering wearable nerve stimulation platforms that emphasize patient empowerment and personalized care. By re-imagining neuromodulation through innovative, proven technologies, Avation Medical aims to enhance the management of chronic conditions, offering solutions that prioritize the needs and experiences of patients.

Cour Pharmaceuticals Development Co Inc, founded in 2012 and based in Elmhurst, Illinois, operates in the pharmaceutical sector with a focus on developing an immune-modifying platform. This platform aims to achieve antigen-specific tolerance for immune-mediated diseases and provides non-biological therapeutics for conditions such as acute inflammation, autoimmunity, and allergies. The company is engaged in the pharmaceutical development of products related to immunology, pathology, and cardiovascular health, enabling the treatment of various conditions, including encephalitis syndromes, autoimmune disorders, infections, and heart attacks.

Noctrix Health, Inc. is an early-stage medical device company based in Menlo Park, California, founded in 2018. The company specializes in developing therapeutic wearable devices aimed at treating chronic neurological and sleep disorders, particularly focusing on restless leg syndrome. Its innovative device utilizes neural circuitry to alleviate symptoms and promote undisturbed sleep, empowering patients to better manage their chronic medical conditions.

Freya Biosciences is a clinical-stage company focused on women's health, with operations in Copenhagen and Boston. It specializes in developing microbial immunotherapies aimed at addressing significant unmet medical needs across various conditions. The company utilizes a proprietary platform to engineer and manufacture live microbes, ensuring their safety and efficacy for human use. Through this innovative approach, Freya Biosciences seeks to create new treatment options for a range of diseases, striving to make a meaningful impact in the healthcare sector.

Biovitae is engaged in the development of innovative sanitation and lighting systems designed to improve infection control and prevention. The company focuses on creating practical applications from scientific discoveries to enhance human health and quality of life. Its technology includes NO-UV light bulbs and a combination of LED and photocatalysis, which work together to detoxify air and surfaces within homes. By reducing bacterial load, Biovitae aims to provide safer living environments for users.

Cadence Neuroscience, Inc. is an early-stage company focused on developing innovative medical device therapies for epilepsy, central pain, and other neurological disorders. Founded in 2017 and based in Redmond, Washington, the company is leveraging core technology developed at the Mayo Clinic, which is currently under clinical evaluation. Cadence's implantable devices are designed to detect specific brain signals and deliver tailored electrical stimulation to modify neural circuit activity. This approach aims to enhance seizure control and improve treatment methods, offering medical practitioners a customizable solution for managing neurological conditions.

Serenis Health specializes in delivering accessible mental health services through video-based psychotherapy, coaching, and psychological support courses. The company emphasizes the importance of the internet in expanding access to mental health care and utilizes data and digital tools to enhance therapeutic efficacy. Unlike typical online platforms, Serenis operates as a medical center, ensuring that it meets rigorous quality standards akin to those of a polyclinic. Patients can access online psychotherapy by completing a scientific questionnaire, which facilitates a connection to qualified psychotherapists, allowing for effective psychological support via video calls.

Therini Bio is a biotechnology company focused on developing fibrin-targeting therapies aimed at treating inflammatory neurological and retinal diseases. The company leverages insights from research that highlights the role of fibrin in driving chronic innate immune activation, which is implicated in various human diseases with significant unmet medical needs. Currently, Therini Bio is working on therapeutics that aim to protect the nervous system from damage associated with conditions such as multiple sclerosis. By developing specialized antibodies for neuroinflammatory diseases linked to vascular dysfunction, the company seeks to provide healthcare providers with effective treatment options that can improve patient outcomes.

Nuevocor is a preclinical-stage biopharmaceutical company dedicated to developing gene therapy-based treatments aimed at restoring cardiac function in patients with cardiovascular diseases. The firm specifically targets genetic cardiomyopathies, which are characterized by abnormal mechanobiology. By focusing on modulating mechanical force transduction, Nuevocor aims to provide innovative solutions that enable healthcare professionals to effectively treat these conditions and improve heart health in affected individuals.