The Aurora Funds is a venture capital firm based in Cary, North Carolina, with an additional office in Durham. Founded in 1994, it specializes in seed and early-stage investments, primarily focusing on healthcare and information technology sectors. Within healthcare, the firm targets biotechnology, therapeutics, medical devices, healthcare services, and healthcare information technology. In the information technology arena, it emphasizes internet infrastructure, software, data communications, semiconductors, and emerging technologies like photonics and nanotechnology. Aurora Funds typically invests between $50,000 and $2.5 million in initial financing rounds, with total investments ranging from $4 million to $8 million as companies develop. The firm seeks to back companies with enterprise values between $2 million and $40 million and prefers to take a lead or co-lead role while having a board seat in its portfolio companies.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
Argos Therapeutics, Inc. was a biotechnology company based in Durham, North Carolina, focused on developing individualized immunotherapies for cancer, infectious diseases, and autoimmune disorders. Utilizing its proprietary Arcelis technology platform, the company aimed to create personalized treatments, including rocapuldencel-T, which was undergoing Phase III clinical trials for metastatic renal cell carcinoma, and AGS-004, in Phase II trials for human immunodeficiency virus. Argos also explored therapies for transplant rejection and autoimmune diseases, with products in various stages of development targeting conditions such as lupus and other inflammatory disorders. Founded in 1997, the company was previously known as Merix Bioscience, Inc. However, Argos Therapeutics ceased operations and filed for Chapter 7 bankruptcy on September 24, 2019.
Regado Biosciences is a biopharmaceutical company, engages in the discovery and development of aptamer-based antidote-controlled therapeutics. It provides REG1 that is used in patients suffering from acute coronary syndrome who undergo coronary revascularization procedures, which include coronary artery bypass grafting and percutaneous coronary intervention. It was founded in 2001 and headquartered in Durham, North Carolina.
Cardioxyl Pharmaceuticals is a privately held, clinical stage biopharmaceutical company focused on developing therapies for cardiovascular disease. The company specializes in nitroxyl technology, which is aimed at addressing areas of cardiovascular treatment where existing therapies are lacking or ineffective. Cardioxyl has developed a robust portfolio of pre-clinical and clinical candidates, with its lead compound, CXL-1020, currently in clinical development for Acute Decompensated Heart Failure, a prevalent condition among patients over 65 years of age that often leads to hospitalization. Through its innovative approach, Cardioxyl aims to enhance treatment options for patients suffering from cardiovascular diseases.
Argos Therapeutics, Inc. was a biotechnology company based in Durham, North Carolina, focused on developing individualized immunotherapies for cancer, infectious diseases, and autoimmune disorders. Utilizing its proprietary Arcelis technology platform, the company aimed to create personalized treatments, including rocapuldencel-T, which was undergoing Phase III clinical trials for metastatic renal cell carcinoma, and AGS-004, in Phase II trials for human immunodeficiency virus. Argos also explored therapies for transplant rejection and autoimmune diseases, with products in various stages of development targeting conditions such as lupus and other inflammatory disorders. Founded in 1997, the company was previously known as Merix Bioscience, Inc. However, Argos Therapeutics ceased operations and filed for Chapter 7 bankruptcy on September 24, 2019.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
Digitalsmiths specializes in enhancing video providers' capabilities to access extensive video archives and deliver personalized experiences through precise and actionable video metadata. The company's video discovery solutions cater to various content formats and devices, enabling tailored video experiences that increase viewer engagement and revenue opportunities across mobile, broadband, tablet, and television platforms. With a client roster that includes prominent Hollywood studios, broadcasters, distributors, and publishers, Digitalsmiths facilitates personalized search, recommendations, and content discovery for consumers. Founded in 2006 and headquartered in Durham, North Carolina, Digitalsmiths continues to innovate in the video technology space.
Cardioxyl Pharmaceuticals is a privately held, clinical stage biopharmaceutical company focused on developing therapies for cardiovascular disease. The company specializes in nitroxyl technology, which is aimed at addressing areas of cardiovascular treatment where existing therapies are lacking or ineffective. Cardioxyl has developed a robust portfolio of pre-clinical and clinical candidates, with its lead compound, CXL-1020, currently in clinical development for Acute Decompensated Heart Failure, a prevalent condition among patients over 65 years of age that often leads to hospitalization. Through its innovative approach, Cardioxyl aims to enhance treatment options for patients suffering from cardiovascular diseases.
StrikeIron specializes in Data-as-a-Service (DaaS), providing a comprehensive suite of data quality solutions through its cloud platform, IronCloud. The company offers services such as address verification, email verification, phone validation, phone append, SMS text messaging, and sales tax solutions, catering to a diverse range of industries. Its web services can be seamlessly integrated into various applications and systems, enhancing data accuracy and communication efficiency. Additionally, StrikeIron's solutions are pre-integrated with prominent platforms, including Salesforce and Magento, allowing for streamlined deployment and use. The company aims to support businesses in improving their data management and communication processes through its innovative cloud-based offerings.
Centice Corporation specializes in developing devices for drug detection and identification. The company offers solutions for identifying prescription drugs, illicit substances, and mixtures, as well as addressing issues related to narcotics enforcement and counterfeiting. Its notable product, the PASS Rx system, enhances the verification process for dispensed medications by capturing the spectral signature of drugs and comparing it to a known database. Founded in 2003 and headquartered in Morrisville, North Carolina, Centice operates through a network of distributors both domestically and internationally, providing vital tools for drug verification and safety. The company was formerly known as Optopo, Inc. and rebranded to Centice Corporation in February 2008.
Regado Biosciences is a biopharmaceutical company, engages in the discovery and development of aptamer-based antidote-controlled therapeutics. It provides REG1 that is used in patients suffering from acute coronary syndrome who undergo coronary revascularization procedures, which include coronary artery bypass grafting and percutaneous coronary intervention. It was founded in 2001 and headquartered in Durham, North Carolina.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
StrikeIron specializes in Data-as-a-Service (DaaS), providing a comprehensive suite of data quality solutions through its cloud platform, IronCloud. The company offers services such as address verification, email verification, phone validation, phone append, SMS text messaging, and sales tax solutions, catering to a diverse range of industries. Its web services can be seamlessly integrated into various applications and systems, enhancing data accuracy and communication efficiency. Additionally, StrikeIron's solutions are pre-integrated with prominent platforms, including Salesforce and Magento, allowing for streamlined deployment and use. The company aims to support businesses in improving their data management and communication processes through its innovative cloud-based offerings.
Digitalsmiths specializes in enhancing video providers' capabilities to access extensive video archives and deliver personalized experiences through precise and actionable video metadata. The company's video discovery solutions cater to various content formats and devices, enabling tailored video experiences that increase viewer engagement and revenue opportunities across mobile, broadband, tablet, and television platforms. With a client roster that includes prominent Hollywood studios, broadcasters, distributors, and publishers, Digitalsmiths facilitates personalized search, recommendations, and content discovery for consumers. Founded in 2006 and headquartered in Durham, North Carolina, Digitalsmiths continues to innovate in the video technology space.
ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. We have four product candidates in clinical trials. Our most advanced product candidate is ALD-101. We are currently conducting a pivotal Phase 3 clinical trial of ALD-101 to evaluate its efficacy in improving umbilical cord blood, or cord blood, transplants used to treat inherited metabolic diseases in pediatric patients. We are also conducting or supporting Phase 1 or Phase 1/2 clinical trials of three other product candidates ALD--151 to improve cord blood transplants used for the treatment of leukemia; ALD-301 to treat critical limb ischemia; and ALD-201 to treat ischemic heart failure.
Centice Corporation specializes in developing devices for drug detection and identification. The company offers solutions for identifying prescription drugs, illicit substances, and mixtures, as well as addressing issues related to narcotics enforcement and counterfeiting. Its notable product, the PASS Rx system, enhances the verification process for dispensed medications by capturing the spectral signature of drugs and comparing it to a known database. Founded in 2003 and headquartered in Morrisville, North Carolina, Centice operates through a network of distributors both domestically and internationally, providing vital tools for drug verification and safety. The company was formerly known as Optopo, Inc. and rebranded to Centice Corporation in February 2008.
Digitalsmiths specializes in enhancing video providers' capabilities to access extensive video archives and deliver personalized experiences through precise and actionable video metadata. The company's video discovery solutions cater to various content formats and devices, enabling tailored video experiences that increase viewer engagement and revenue opportunities across mobile, broadband, tablet, and television platforms. With a client roster that includes prominent Hollywood studios, broadcasters, distributors, and publishers, Digitalsmiths facilitates personalized search, recommendations, and content discovery for consumers. Founded in 2006 and headquartered in Durham, North Carolina, Digitalsmiths continues to innovate in the video technology space.
Regado Biosciences is a biopharmaceutical company, engages in the discovery and development of aptamer-based antidote-controlled therapeutics. It provides REG1 that is used in patients suffering from acute coronary syndrome who undergo coronary revascularization procedures, which include coronary artery bypass grafting and percutaneous coronary intervention. It was founded in 2001 and headquartered in Durham, North Carolina.
ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. We have four product candidates in clinical trials. Our most advanced product candidate is ALD-101. We are currently conducting a pivotal Phase 3 clinical trial of ALD-101 to evaluate its efficacy in improving umbilical cord blood, or cord blood, transplants used to treat inherited metabolic diseases in pediatric patients. We are also conducting or supporting Phase 1 or Phase 1/2 clinical trials of three other product candidates ALD--151 to improve cord blood transplants used for the treatment of leukemia; ALD-301 to treat critical limb ischemia; and ALD-201 to treat ischemic heart failure.
Cardioxyl Pharmaceuticals is a privately held, clinical stage biopharmaceutical company focused on developing therapies for cardiovascular disease. The company specializes in nitroxyl technology, which is aimed at addressing areas of cardiovascular treatment where existing therapies are lacking or ineffective. Cardioxyl has developed a robust portfolio of pre-clinical and clinical candidates, with its lead compound, CXL-1020, currently in clinical development for Acute Decompensated Heart Failure, a prevalent condition among patients over 65 years of age that often leads to hospitalization. Through its innovative approach, Cardioxyl aims to enhance treatment options for patients suffering from cardiovascular diseases.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
StrikeIron specializes in Data-as-a-Service (DaaS), providing a comprehensive suite of data quality solutions through its cloud platform, IronCloud. The company offers services such as address verification, email verification, phone validation, phone append, SMS text messaging, and sales tax solutions, catering to a diverse range of industries. Its web services can be seamlessly integrated into various applications and systems, enhancing data accuracy and communication efficiency. Additionally, StrikeIron's solutions are pre-integrated with prominent platforms, including Salesforce and Magento, allowing for streamlined deployment and use. The company aims to support businesses in improving their data management and communication processes through its innovative cloud-based offerings.
Cropsolution
Series C in 2005
Cropsolution uses chemistry technology to discover and develop agrochemicals to protect crops from diseases, weeds, and pests.
Nextreme designs and manufactures micro-scale thermal and power management products for the semiconductor, photonics, consumer, automotive and defense/aerospace industries. The company has embedded cooling and power generation capabilities into the widely accepted copper pillar bumping process used in high-volume electronic packaging. Nextreme’s breakthrough addresses the most challenging thermal and power management constraints in electronics today, and delivers the only fully-scalable technology solution by leveraging the existing, high-volume flip chip manufacturing infrastructure. By minimizing the need for manufacturing changes and focusing on developing a seamless design-in solution, Nextreme is changing the future of thermal and power management for the entire electronics industry.
StrikeIron specializes in Data-as-a-Service (DaaS), providing a comprehensive suite of data quality solutions through its cloud platform, IronCloud. The company offers services such as address verification, email verification, phone validation, phone append, SMS text messaging, and sales tax solutions, catering to a diverse range of industries. Its web services can be seamlessly integrated into various applications and systems, enhancing data accuracy and communication efficiency. Additionally, StrikeIron's solutions are pre-integrated with prominent platforms, including Salesforce and Magento, allowing for streamlined deployment and use. The company aims to support businesses in improving their data management and communication processes through its innovative cloud-based offerings.
HyperBranch Medical Technology, Inc. is a medical device company focused on developing and marketing innovative products for traumatic and surgically induced wounds. Its flagship product, OcuSeal, is a liquid ocular bandage that provides an immediate protective barrier for the eye by covering openings on its surface. The company also produces Adherus Dural Sealant, which assists in dural repair during cranial and spinal surgeries, including treatments for intracranial aneurysms and tumors. Additionally, HyperBranch offers Adherus Hernia Mesh Fixation, a device designed to replace traditional methods such as tacks and sutures in hernia repair procedures. The company's biosurgical devices aim to enhance patient recovery by reducing complications during surgery.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
StrikeIron specializes in Data-as-a-Service (DaaS), providing a comprehensive suite of data quality solutions through its cloud platform, IronCloud. The company offers services such as address verification, email verification, phone validation, phone append, SMS text messaging, and sales tax solutions, catering to a diverse range of industries. Its web services can be seamlessly integrated into various applications and systems, enhancing data accuracy and communication efficiency. Additionally, StrikeIron's solutions are pre-integrated with prominent platforms, including Salesforce and Magento, allowing for streamlined deployment and use. The company aims to support businesses in improving their data management and communication processes through its innovative cloud-based offerings.
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine.
The company can deliver an instantaneous snapshot of the entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions.
Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
StemCo Biomedical, Inc. was founded in 1999 and is located in the Research Triangle Park area of NC. The Company is engaged in the development, manufacture and distribution of a series of medical products designed to improve therapeutic transplantation of adult hematopoetic stem and progenitor cells derived from bone marrow, peripheral blood or umbilical cord blood. Addressing a market of more than $1 billion annually, the Company will have a series of products on the market starting in 2002 that identify, sort and custom-engineer stem cell grafts based upon cellular expression of ALDH resulting in what may be better, more effective stem cell transplants in the future.
Regado Biosciences is a biopharmaceutical company, engages in the discovery and development of aptamer-based antidote-controlled therapeutics. It provides REG1 that is used in patients suffering from acute coronary syndrome who undergo coronary revascularization procedures, which include coronary artery bypass grafting and percutaneous coronary intervention. It was founded in 2001 and headquartered in Durham, North Carolina.
Cropsolution
Series A in 2002
Cropsolution uses chemistry technology to discover and develop agrochemicals to protect crops from diseases, weeds, and pests.
Norak Biosciences, Inc., headquartered in Research Triangle Park, NC, is a private biotechnology company. Norak is utilizing its proprietary Transfluor technology to become a world leader in the discovery and development of drugs that regulate G protein-coupled receptors.
Regado Biosciences is a biopharmaceutical company, engages in the discovery and development of aptamer-based antidote-controlled therapeutics. It provides REG1 that is used in patients suffering from acute coronary syndrome who undergo coronary revascularization procedures, which include coronary artery bypass grafting and percutaneous coronary intervention. It was founded in 2001 and headquartered in Durham, North Carolina.
StemCo Biomedical, Inc. was founded in 1999 and is located in the Research Triangle Park area of NC. The Company is engaged in the development, manufacture and distribution of a series of medical products designed to improve therapeutic transplantation of adult hematopoetic stem and progenitor cells derived from bone marrow, peripheral blood or umbilical cord blood. Addressing a market of more than $1 billion annually, the Company will have a series of products on the market starting in 2002 that identify, sort and custom-engineer stem cell grafts based upon cellular expression of ALDH resulting in what may be better, more effective stem cell transplants in the future.
Porivo Technologies, Inc. is developing an Internet-enabled distributed computing platform to harness the unused processing power of idle PCs. By aggregating this tremendous underutilized resource, and creating a sizeable network of users, Porivo's software will create a massively parallel meta-computer with incredible processing power.
Alerts.com, Inc.
Series B in 2000
Alerts.com remotely monitors Web sites to deliver personalized, persistent search results via wireless devices, interactive voice, text and email. The Alerts.com system offers both content alerting capabilities and delivery of content directly to wireless devices using SMS or WAP protocols. Offered as a service through our partners and through Alerts.com's own Internet site, users request to be notified when specific Web content - like a news story or a product price - satisfies the user's alert parameters. The Alerts.com system provides business-to-business and business-to-consumer markets with a seamless, diligent infrastructure service that helps build and manage customer relationships by delivering information when and where people need it. The service, by exposing and delivering dynamic content notifications, generates qualified repeat visits to partners' sites and serves an indispensable role in opt-in, affinity-based marketing efforts.
Interadnet Inc. is a company that specializes in automated ad tracking technology and digital advertising services. It provides an internet advertising platform designed to enhance the effectiveness of online advertising campaigns. By optimizing and tracking advertising investments, Interadnet enables clients to efficiently manage their digital marketing efforts, ensuring better performance and return on investment.
Technauts to meet the demand of small to medium businesses, departments and branch offices for simple affordable.
Alerts.com, Inc.
Series A in 1999
Alerts.com remotely monitors Web sites to deliver personalized, persistent search results via wireless devices, interactive voice, text and email. The Alerts.com system offers both content alerting capabilities and delivery of content directly to wireless devices using SMS or WAP protocols. Offered as a service through our partners and through Alerts.com's own Internet site, users request to be notified when specific Web content - like a news story or a product price - satisfies the user's alert parameters. The Alerts.com system provides business-to-business and business-to-consumer markets with a seamless, diligent infrastructure service that helps build and manage customer relationships by delivering information when and where people need it. The service, by exposing and delivering dynamic content notifications, generates qualified repeat visits to partners' sites and serves an indispensable role in opt-in, affinity-based marketing efforts.
Accipiter offers online advertising solutions and services worldwide. It offers AdManager, an ad management solution that allows to increase targeting capabilities to speed ad delivery and to monitor and control inventory projections in real-time; Ad Trafficking, which provides AdManager hosted clients with outsourced and customized solution to administer the campaign management process; AdMarket, a real-time bid-for-placement technology enabling publishers to operate branded online advertising marketplaces and transact with advertisers who are requesting a pay-per-click pricing model; and Visitor Interest Behavioral Engine, a behavioral targeting solution that delivers promotions and content to interested prospects. Accipiter is based in Raleigh, North Carolina with an additional office in London, United Kingdom.
Accipiter offers online advertising solutions and services worldwide. It offers AdManager, an ad management solution that allows to increase targeting capabilities to speed ad delivery and to monitor and control inventory projections in real-time; Ad Trafficking, which provides AdManager hosted clients with outsourced and customized solution to administer the campaign management process; AdMarket, a real-time bid-for-placement technology enabling publishers to operate branded online advertising marketplaces and transact with advertisers who are requesting a pay-per-click pricing model; and Visitor Interest Behavioral Engine, a behavioral targeting solution that delivers promotions and content to interested prospects. Accipiter is based in Raleigh, North Carolina with an additional office in London, United Kingdom.
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