Becton, Dickinson and Company

Day Zero Diagnostics (DZD) is developing a new class of diagnostic that enables a physician to switch from broad spectrum antibiotic therapy to a targeted antibiotic in 5 hours rather than the 2-5 days that it typically takes today. Unlike other molecular diagnostics that can only detect a handful of specific targets, DZD uses the entire genomic sequence and our proprietary Keynome™ algorithm to identify a comprehensive range of bacterial pathogens and their resistance characteristics within hours.

Vicarious Surgical Inc. is a Massachusetts-based company that specializes in developing a robotic system for minimally invasive surgery, integrating virtual reality technology to enhance surgical precision. Founded in 2014, the company focuses on creating a surgical robot that allows surgeons to perform procedures with improved 3D visualization and accurate control. The Vicarious Surgical Robotic System is specifically designed for abdominal access and utilizes a single port for entry, aiming to streamline surgical processes and improve patient outcomes.

Tepha, Inc. is a medical device company based in Lexington, Massachusetts, specializing in the development and manufacture of components utilizing proprietary biomaterial technology. The firm focuses on producing a new class of absorbable biomaterials known as polyhydroxyalkanoates (PHAs), which are engineered with recombinant DNA technology. Tepha's product offerings include monofilament sutures and meshes designed for various surgical applications, such as soft tissue approximation, hernia repair, and pelvic floor reconstruction. Additionally, the company provides the P4HB regenerative polymer scaffold for treating stress urinary incontinence, along with surgical films and composite meshes that facilitate tissue attachment and minimize complications. Tepha aims to address unmet medical needs across multiple fields by offering innovative solutions characterized by superior flexibility, elasticity, biocompatibility, and strength retention.

Velano Vascular, Inc. is a medical device company based in San Francisco, California, that specializes in needle-free vascular access devices for blood collection. Its primary product, PIVO, is a single-use, sterile device that connects to indwelling peripheral IV lines to facilitate blood draws, significantly reducing the need for multiple needle sticks and minimizing central line access complications. Founded by a patient and a physician, Velano Vascular aims to alleviate the stress and anxiety patients often experience during blood draws in hospital settings. The device enhances safety and efficiency for healthcare providers while prioritizing patient comfort by reducing pain and discomfort associated with traditional blood collection methods. The company collaborates with leading hospital systems and organizations focused on patient-centered care and is supported by various investment partners.

GSL Solutions is a medical technology company that specializes in the development of devices designed for the storage and tracking of controlled substances and patient-specific medications. The company's product line includes devices such as IntelliCab, IntelliVault, IntelliVault MTB, and IntelliVault RD, which enhance the security, efficiency, and compliance of medication storage. In addition to improving inventory management and regulatory compliance, these devices also provide analytic capabilities aimed at enhancing patient safety. Overall, GSL Solutions focuses on innovative solutions that facilitate better management of will-call prescriptions and controlled substances in the healthcare sector.

Cubex Systems is the developer of cloud-based inventory management software. The company's inventory management software offers real-time reporting to deliver intuitive analytics that prioritizes operational demands, spend management and regulatory compliance, enabling the medical, dental and veterinary markets to lower costs associated with medication and optimize inventory supply management.

TVA Medical, Inc. is a medical device company based in Austin, Texas, that specializes in the development and manufacture of catheter-based equipment and solutions aimed at treating end-stage renal disease (ESRD) and peripheral vascular diseases. Founded in 2009, TVA Medical focuses on creating innovative and minimally invasive therapies to improve patient outcomes. The company has garnered funding from Santé Ventures and operates as a subsidiary of Becton, Dickinson and Company since July 2018.

MedAware Ltd specializes in developing solutions aimed at detecting and eliminating prescription errors to enhance patient safety and reduce healthcare costs. Founded in 2012 and headquartered in Raanana, Israel, the company utilizes advanced data analytics and machine learning algorithms to analyze extensive electronic medical records. Its offerings include the MedAS alerting system for real-time alerts on prescription errors, MedRIM for risk management support, MedQC for quality control assistance, and MedRAF to reduce alert fatigue. These tools enable healthcare providers, pharmacy benefit management companies, and pharmacy chains to leverage big data effectively, identify potential prescription errors related to drug interactions, dosages, and allergies, and ultimately improve patient outcomes.

Magentiq Eye Ltd., a medical device company, which provides products for endoscopic medical procedures. The company offers automatic polyp detection system (APDS); APDS- RT, a software that runs on local device and server and gets the video feed from the endoscopic camera used by the physician in real time; and APDS-OFL, a software that runs in offline mode on pre-recorded colonoscopy videos. It also provides big data management and analysis, computer vision, video analysis, and colonoscopy screening test. The company was founded in 2014 and is based in Haifa, Israel.

C. R. Bard, headquartered in Murray Hill, NJ, is a leading multinational developer, manufacturer and marketer of innovative, life-enhancing medical technologies in the fields of vascular, urology, oncology and surgical specialty products.

Caesarea Medical Electronics Ltd. designs and develops a range of infusion and syringe pumps in the United States. It offers epidural infusion, dual and four channel infusion, ambulatory syringe, and enteral feeding and syringe pumps, as well as intravenous medication delivery and multi functional infusion therapy devices, and a range of disposable administration sets. The company also provides accessories, including chargers, carrying pouches, carrying back bags, syringe pump carrying pouch waist or shoulders straps, lock boxes, and cables. Its products are used by clinical research companies; and various treatment settings, such as hospital, homecare, and transport or emergency medicine. The company was founded in 1993 and is based in Caesarea, Israel.

CRISI Medical Systems, Inc. (CRISI) is a privately-funded medical device company dedicated to improving the safety and delivery of intravenous (IV) injectable medications through technology and innovation. They are on the forefront of companies developing developing innovative solutions to advance the standard of care in injectable drug delivery.

GenCell Biosystems is focused on advancing molecular biology through its innovative Composite Liquid Cell (CLC) platform technology. This technology enables a novel approach to confining, transporting, combining, processing, and analyzing biological reactions, which facilitates the extraction and preparation of samples, library preparation for next-generation sequencing, PCR genotyping, quantitative PCR, digital PCR, and proteomic assays. The versatility of CLCs allows them to be customized to meet diverse protocol requirements, addressing significant challenges in the fields of genomics and proteomics. By commercializing these instruments, GenCell aims to provide valuable tools for researchers in life sciences.

CareFusion Corporation (CareFusion) is a global medical technology company. The Company operates in two segments: Medical Systems and Procedural Solutions. The Medical Systems segment is organized around its medical equipment businesses. The Company’s Medical Systems segment’s business units and product lines include Infusion Systems, Dispensing Technologies, and Respiratory Technologies. The Procedural Solutions segment is organized around the Company’s disposable products and reusable surgical instruments businesses. The Company’s Procedural Solutions segment’s business units and product lines include Infection Prevention, Medical Specialties and Specialty Disposables. In August 2011, the Company acquired Rowa. In June 2012, the Company acquired U.K. Medical Limited. In July 2012, Natus Medical, Inc. acquired the Nicolet neurodiagnostic business from CareFusion.

Alverix focuses on producing low cost, handheld reader devices with the accuracy and precision of laboratory instrumentation. The company partners with diagnostic and OEM manufacturers seeking to increase current test accuracy, improve the portability of existing tests, or develop new assays for use in physician offices, laboratory outreach locations, retail clinics, and patient homes. With strength in product design, product development, and high volume manufacturing, Alverix is leading the transition of diagnostic testing from the laboratory to all locations where immediate results are critical to patient care.

Cato Software Solutions provides an automated system that creates and shares data to help reduce human error, standardize practice.

Safety Syringes, Inc. designs, manufactures, and markets safety devices for the pharmaceutical industry in the United States, Canada, Europe, India, and the Russian Federation. It offers UltraSafe needle guards to attach to prefilled glass syringes used with vaccines, low molecular weight heparins, and other medicines.

Sirigen, Inc. is a biotechnology company based in La Jolla, California, that specializes in High Sensitivity Fluorescence (HSF) detection technology for the diagnostic and life science markets. Established in 2003, the company develops innovative polymeric materials that enhance fluorescence detection capabilities, leading to improved performance in various applications, including immunoassays, flow cytometry, molecular diagnostics, and more. Sirigen's products, which include a range of fluorescent polymers and conjugates, are designed to simplify sample processing and instrumentation requirements, making them suitable for high-volume screening in diagnostics and personal care applications. As a subsidiary of Becton, Dickinson and Company, Sirigen continues to focus on advancing detection techniques and developing next-generation diagnostic tools.

BD Kiestra Total Lab Automation develops solutions and services for medical bacteriology laboratories. It offers total lab and work cell automation solutions, and automation/mechanization modules. The company also provides solutions and products for use in a water or food microbiology laboratories.

Carmel Pharma ab engages in the manufacture and distribution of products that improve the quality of life of people who prepare, administer, and dispose of hazardous drugs. It offers the PhaSeal System, a closed-system drug transfer device that prevents hazardous drug interaction with the environment. The company's PhaSeal product is implemented in various cancer centers, oncology practices, and specialty pharmacies in the United States, as well as facilities in Europe and Asia. Carmel Pharma ab was founded in 1994 and is headquartered in Mölndal, Sweden with an additional office in Columbus, Ohio.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

HandyLab is a medical technology company that develops and manufactures molecular diagnostic assays and automation platforms The company’s proprietary platform reduces the time, cost, and complexity of testing while improving the quality of results. Using patented real-time microfluidic PCR technology, its products are positioned to decentralize nucleic acid testing. HandyLab was founded in 2000 and is based in Ann Arbor, Michigan. It was acquired by Becton, Dickinson and Company in 2009.

Cytopeia Inc. is a company based in Seattle, Washington, that specializes in the manufacturing of automated influx cell sorters. These advanced instruments are designed to assist scientists in analyzing and characterizing cells, facilitating research across various fields, including cell therapy, stem cell research, drug discovery and development, and marine biology. By providing innovative solutions for cell sorting, Cytopeia aims to enhance the capabilities of researchers and contribute to advancements in biological studies and applications.

Plasso Technology is develops surface-critical research tools utilizing functional coating technology for applications in glycomics and cell culture. The company offers BD Heparin Binding Plate that immobilizes the heparin without modification

TriPath Imaging, Inc. manufactures and markets diagnostic equipment and products for cervical cytology screening. The company’s products include microbial identification tests for differential detection and identification of the causative agents for vaginitis; ethanol based fixative systems to collect, preserve, hemolyze, transport, and transfer cytology specimens to a glass slide; slide profilers for prioritizing slides based on likelihood of abnormality to help cytotechnologists reduce false negatives;

GeneOhm Sciences designs, develops, and delivers nucleic acid-based diagnostic solutions. It focuses on serving the unmet diagnostic needs in a wide range of diseases including inherited disease, infectious disease and oncology. It is developing rapid, nucleic acid-based systems that will detect and identify infectious agents and genetic variations. GeneOhm Sciences is dedicated to offering laboratories and clinical scientists cutting-edge, FDA-approved, molecular based tests that can provide results in less than two hours. Established in San Diego, California in 2001, GeneOhm Sciences merged with Infectio Diagnostic, Inc. of Québec, Canada in 2004. The integrated company combines an extensive portfolio of proprietary technology, strong industry expertise and capabilities with an experienced and accomplished management team to lead the way. Most of GeneOhm’s development focus is on the applications electric current flowing through DNA as a means to detect genetic mutations. GeneOhm was recently acquired by the BD Pharmaceuticals group.

Atto Bioscience, established in 1985, specializes in providing innovative solutions for pharmaceutical, academic, and research sectors focused on cellular biology. The company offers a unique integration of biology, imaging instrumentation, engineering, and manufacturing, resulting in a comprehensive suite of assays, instrumentation, and services tailored for the life sciences and toxicology communities. With a strong emphasis on in-house technology development, Atto Bioscience adapts quickly to customer needs, delivering state-of-the-art imaging solutions for drug discovery and cellular research. Since reorganizing in 2001, Atto has expanded its capabilities by recruiting leading scientists and enhancing its management team, which has facilitated its entry into the high-throughput cell imaging market. The company's technologies support various applications, from secondary screening techniques to pre-clinical research, promoting efficient strategies that reduce time and increase success rates in drug development.

StemCo Biomedical, Inc. was founded in 1999 and is located in the Research Triangle Park area of NC. The Company is engaged in the development, manufacture and distribution of a series of medical products designed to improve therapeutic transplantation of adult hematopoetic stem and progenitor cells derived from bone marrow, peripheral blood or umbilical cord blood. Addressing a market of more than $1 billion annually, the Company will have a series of products on the market starting in 2002 that identify, sort and custom-engineer stem cell grafts based upon cellular expression of ALDH resulting in what may be better, more effective stem cell transplants in the future.

GENTEST Corporation specializes in developing innovative systems for the in vitro analysis of xenobiotic metabolism and toxicity, particularly focusing on drug metabolism and toxicology. Founded in 1983, the company initially concentrated on using cultured human cells for genotoxicity assays before expanding its research to include cytochrome P450 cDNA-expression techniques in 1985. This expansion led to the first commercial offering of cDNA-expressed human cytochrome P450 enzymes in 1990. GENTEST is recognized for its expertise in this field, with its scientists contributing to peer-reviewed journals and international symposia. The company’s products are essential for pharmaceutical and biotech industries, providing tools to screen drug candidates for adverse interactions and potential liver toxicity. Over the years, GENTEST has significantly broadened its range of products, enhancing the specificity and activity of its enzymes.

Saf-T-Med, Inc. (STM), a Chicago-based developer of patented needle technology designed to protect health care workers against accidental needlestick injuries.

Clontech Laboratories provides kits, reagents, and services that help researchers explore questions about gene discovery, regulation, and function. As a member of the Takara Bio Group, Clontech is part of a company that holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Clontech's mission is to develop high-quality innovative tools and services to accelerate discovery.

As of February 9, 1999, Biometric Imaging, Inc. was acquired by Becton, Dickinson and Company. Biometric Imaging, Inc. develops cell based diagnostic products and high throughput drug discovery technology. Their research is based on a proprietary technology called microvolume fluorimetry, and they primarily serve the transfusion medicine, infectious diseases, and oncology markets. The company was founded in 1991 and is based in Mountain View, California.