BioCrossroads

OmniVis technology detects pathogens right at the source. Our easy-to-use hardware device and disposable test kit reduces the detection process to 30 minutes, accurately and affordably.

BioDynamic Imaging delivers better drug assessment in three-dimensional (3D) living tissue samples, revealing a comprehensive phenotypic response that is more physiologically meaningful than from conventional 2D or monolayer screens. Our technique is label-free and probes up to 1 mm deep in living tissue to study drug response in heterogeneous tissue environments. BioDynamic Imaging converts all forms of functional cellular motions into contrast maps of cellular mechanisms of action.

FlowCo is a medical device company, develops products to improve the flow of blood through the vascular system.

Kovina Therapeutics operates as a pre-clinical biotechnology company aims to discover a non-surgical, medical treatment for Human Papillomavirus (HPV) infections and cancers.

Lumavate is an enterprise platform for building progressive web apps (PWAs) at scale. Through the Lumavate platform, companies deliver highly-personalized mobile experiences throughout the entire customer journey. These mobile experiences drive increased adoption and long-term engagement via smart activation methods. Visit lumavate.com to learn more.

Scioto Biosciences is a developer of Activated Bacterial Therapeutics (ABT) platform intended to deliver live bacteria to the gut. The company is developing innovative therapies devoted to having a transformative impact on the delivery of microbiome therapeutics, enabling medical practitioners to advance healing through microbiome therapeutics.

Sexton Biotechnologies announced today that it has raised $5 million in growth capital and is the first company incubated by Indianapolis-based Cook Regentec to secure outside investment capital and spin out as an independent biotechnology company. In addition to ongoing research and product development, Sexton Biotechnologies will expand and scale commercialization of its portfolio of container closure and media supplementation tools for cell and gene therapy bioproduction.

SonarMed, Inc. provides solutions for the placement and monitoring of endotracheal tubes that are used in patients who cannot breathe on their own. Its SonarMed AirWave is a non invasive, adjunctive device that provides direct, precise, and real time monitoring of endotracheal tube position and function, which aids in detecting potentially dangerous or fatal endotracheal tube conditions. The company was founded in 2005 and is based in Carmel, Indiana.

Novosteo Inc. develops and manufactures drugs to heal bone fractures. The company was founded in 2017 and is based in West Lafayette, Indiana.

Scioto Biosciences is a developer of Activated Bacterial Therapeutics (ABT) platform intended to deliver live bacteria to the gut. The company is developing innovative therapies devoted to having a transformative impact on the delivery of microbiome therapeutics, enabling medical practitioners to advance healing through microbiome therapeutics.

Allinaire Therapeutics aims to develop novel therapeutics for Chronic Obstructive Pulmonary Disease (COPD) and other pulmonary diseases. The technology is based on the discovery by scientific founders Irina Petrache, MD, and Matthias Clauss, Ph.D. of a novel therapeutic target that plays a central role in the development and progression of lung disease.

Allinaire Therapeutics aims to develop novel therapeutics for Chronic Obstructive Pulmonary Disease (COPD) and other pulmonary diseases. The technology is based on the discovery by scientific founders Irina Petrache, MD, and Matthias Clauss, Ph.D. of a novel therapeutic target that plays a central role in the development and progression of lung disease.

Lumavate is an enterprise platform for building progressive web apps (PWAs) at scale. Through the Lumavate platform, companies deliver highly-personalized mobile experiences throughout the entire customer journey. These mobile experiences drive increased adoption and long-term engagement via smart activation methods. Visit lumavate.com to learn more.

Sabanto is a farming-as-a-service performing row-crop field operations using low-cost autonomous systems.

Lumavate is an enterprise platform for building progressive web apps (PWAs) at scale. Through the Lumavate platform, companies deliver highly-personalized mobile experiences throughout the entire customer journey. These mobile experiences drive increased adoption and long-term engagement via smart activation methods. Visit lumavate.com to learn more.

Sexton Biotechnologies announced today that it has raised $5 million in growth capital and is the first company incubated by Indianapolis-based Cook Regentec to secure outside investment capital and spin out as an independent biotechnology company. In addition to ongoing research and product development, Sexton Biotechnologies will expand and scale commercialization of its portfolio of container closure and media supplementation tools for cell and gene therapy bioproduction.

SpeechVive is a medical technology company that specializes in providing a communication solution for people with Parkinson's Disease. It also specializes in the fields of healthcare, medical, and medical device manufacturing. The company was founded in 2011 and is headquartered in Lafayette, Indiana.

Apexian Pharmaceuticals, Inc., a clinical stage biotechnology company, develops novel compounds to treat cancer. Its lead drug candidate include APX3330, a oral anticancer agent that targets the APE1/Ref-1 redox protein, a molecule found in many cancers, including tumors of the colon, lung, breast, pancreas, and others. Apexian Pharmaceuticals, Inc. was formerly known as ApeX Therapeutics, Inc. and changed its name to Apexian Pharmaceuticals, Inc. in October 2016. The company was founded in 2007 and is headquartered in Indianapolis, Indiana.

MBX Biosciences is a biotechnology company that develops therapies to treat rare endocrine diseases where there is inadequate treatment available. It focuses on the discovery, development, and commercialization of first-in-class endocrine therapeutics. The company was founded in 2018 and headquartered in Carmel, Indiana.

ImmuneWorks develops immune tolerance treatments for patients with serious autoimmune diseases in the lung. The company was founded in 2006 to develop safe and effective immune tolerance treatments for patients with serious autoimmune diseases of the lung. The scientific foundation of the company is ImmuneWorks' groundbreaking discovery that antigen-specific autoimmunity is responsible for the disease in over one-half of idiopathic pulmonary fibrosis (IPF) patients. It was incorporated in 2006 and is based in Indianapolis, Indiana.

Assembly Pharmaceuticals is a virology-focused biopharmaceutical company with a discovery platform and programs based on proprietary Core Protein Allosteric Modulators (CpAMs) for the treatment of viral infections, starting with hepatitis B (HBV). CpAMs can alter the activities of the HBV core protein, a unique viral protein with no human analogue that is involved in multiple stages of the HBV life cycle. In contrast to current therapies that only suppress HBV, Assembly Pharmaceutical’s CpAMs may have curative potential by eliminating the viral reservoir in infected individuals. Hepatitis B infection has a worldwide prevalence of over 350 million and more than 600,000 people die every year from complications associated with chronic HBV. Assembly has operations in Indiana and San Francisco.

Scioto Biosciences is a developer of Activated Bacterial Therapeutics (ABT) platform intended to deliver live bacteria to the gut. The company is developing innovative therapies devoted to having a transformative impact on the delivery of microbiome therapeutics, enabling medical practitioners to advance healing through microbiome therapeutics.

MBX Biosciences is a biotechnology company that develops therapies to treat rare endocrine diseases where there is inadequate treatment available. It focuses on the discovery, development, and commercialization of first-in-class endocrine therapeutics. The company was founded in 2018 and headquartered in Carmel, Indiana.

Calibrium is an emerging privately held biopharmaceutical company focused on developing a portfolio of novel drug candidates for the treatment of diabetes and related metabolic diseases. Calibrium was co-founded by Fritz French, Calibrium’s Chief Executive Officer, and Richard DiMarchi, PhD, Calibirum’s Chief Scientific Officer.

Bioscience Vaccines is a life-science company with proprietary adjuvant technology referred to as Matrix Immune Modulator and is based in the Purdue Research Park in West Lafayette, Ind. The company's products originated in the laboratory of Dr. Mark Suckow of the University of Notre Dame and are based on a technology discovered at Purdue University. The company's technology has the potential to be formulated as a companion product with vaccine products already approved and marketed for use by the FDA for the prevention of specific human and animal diseases.

Scioto Biosciences is a developer of Activated Bacterial Therapeutics (ABT) platform intended to deliver live bacteria to the gut. The company is developing innovative therapies devoted to having a transformative impact on the delivery of microbiome therapeutics, enabling medical practitioners to advance healing through microbiome therapeutics.

CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Diagnotes, Inc., a digital healthcare company, provides a platform to improve communication and collaboration for the healthcare industry. It offers Diagnotes, a clinical communication platform solution that is used for secure communication, provider scheduling, patient data, discussion documentation, patient engagement, and admin and reporting. The company's Diagnotes helps patients, physicians, care teams, hospitals, health systems, and physician practices to facilitate, track, and manage all patient-related communications. Diagnotes, Inc. was incorporated in 2010 and is based in Indianapolis, Indiana.

Gate Neurosciences is a healthcare company that offers neuroscience-related medical services. The company is developing the next-generation of targeted CNS therapies, leveraging precision medicine approaches to develop breakthrough drugs for psychiatric and neurologic diseases. It was founded in 2018 and is headquartered in Carmel, IN, USA.