BlueTree Allied Angels

CytoAgents, Inc. is a biotechnology company based in Pittsburgh, Pennsylvania, established in 2018. The company specializes in developing protein-based drugs aimed at treating viral infections, particularly influenza, and addressing life-threatening symptoms associated with Cytokine Release Syndrome (CRS). CRS is an overreaction of the immune system that results in systemic inflammation, often referred to as a cytokine storm. One of its primary products, GP1681, acts as an agonist of a G-protein coupled receptor, targeting the immune response in various medical conditions. CytoAgents focuses on creating treatments for multiple indications with significant unmet medical needs, including those arising from oncology CAR-T cell therapy, COVID-19, and respiratory epidemics, thereby providing healthcare professionals with innovative tools to manage patients experiencing severe immune reactions.

Erin is a smart employee referral platform based in Pittsburgh, Pennsylvania, that enhances employee referral programs to yield higher-quality candidates who tend to stay longer with organizations. Founded in 2018, Erin's platform simplifies the referral process by automatically notifying employees about new job openings and enabling them to submit referrals while tracking associated bonuses. This streamlined approach reduces the administrative burden for both employees and employers, ensuring effective communication through automated email and mobile notifications. By leveraging technology, Erin offers a cost-effective alternative to traditional recruitment methods, making it easier for organizations to harness the potential of their workforce in recruiting top talent.

OndeCare operates as a premium in-home care marketplace that provides a seamless platform for booking high-quality care services for individuals of all ages. The company specializes in matching clients with professional caregivers, ensuring reliable support tailored to diverse needs and schedules. With a focus on concierge-level service, OndeCare allows users to arrange care in just minutes, all while maintaining competitive pricing comparable to traditional home care options. Additionally, OndeCare serves as an employee benefit solution, offering businesses a way to enhance their workforce's well-being through effective caregiving support. This dual approach not only meets the caregiving requirements of families but also creates meaningful job opportunities for local care, safety, and education professionals.

C360 Technologies, Inc., established in 2008 and based in Wexford, Pennsylvania, specializes in manufacturing innovative video products for broadcast and over-the-top (OTT) platforms. The company offers non-stitched immersive video solutions, including cameras and workstations, that directly connect with broadcasters' backhaul systems, providing multiple live HD-SDI outputs and enhanced replay systems for real-time broadcast production. C360's products enable simultaneous live television events and 4K streaming to OTT platforms, empowering users with independent control of camera location and functions during live events.

Augment Therapy, Inc. is a Cleveland-based company that develops an interactive augmented reality software solution aimed at enhancing pediatric physical therapy. Established in 2017, its platform facilitates remote monitoring and real-time sessions for patients, allowing therapists to automate data collection during therapy. Designed by a pediatric physical therapist, the software engages and motivates children in their rehabilitative exercises through gamified technology. It utilizes depth-sensing camera technology and features a library of evidence-based exercises and interactive games, enabling therapists to collect and analyze objective patient data while making therapeutic activities more enjoyable for young users.

OndeCare operates as a premium in-home care marketplace that provides a seamless platform for booking high-quality care services for individuals of all ages. The company specializes in matching clients with professional caregivers, ensuring reliable support tailored to diverse needs and schedules. With a focus on concierge-level service, OndeCare allows users to arrange care in just minutes, all while maintaining competitive pricing comparable to traditional home care options. Additionally, OndeCare serves as an employee benefit solution, offering businesses a way to enhance their workforce's well-being through effective caregiving support. This dual approach not only meets the caregiving requirements of families but also creates meaningful job opportunities for local care, safety, and education professionals.

Edge Case Research is a company based in Pittsburgh, Pennsylvania, with an additional office in Unterschleißheim, Germany, specializing in developing software products and safety systems for companies involved in self-driving car technology. Founded in 2013, the firm focuses on testing vehicle software and artificial intelligence without requiring physical vehicles. Its key offerings include Hologram, a platform for identifying and addressing edge cases that challenge machine learning, and Switchboard, a cloud-based tool for automated robustness testing of complex software. The company employs Model-based Iterative System Safety Analysis to pinpoint and model safety risks in intricate systems. Additionally, Edge Case Research provides embedded software best practices assessment and training services. It serves industries such as autonomous vehicles and robotics, consumer electronics and the Internet of Things, and industrial controls and embedded systems.

Gridwise, Inc. develops and operates a mobile application designed for rideshare and delivery drivers, enabling them to enhance their earnings and manage their business operations efficiently. Launched in 2016 and based in Pittsburgh, Pennsylvania, the Gridwise app offers a range of features, including real-time alerts on traffic, weather, and local events, as well as tools for tracking mileage and analyzing earnings. The application also helps users prepare detailed tax reports and calculate deductions, thereby facilitating better financial management. With its focus on providing demand insights and performance tracking, Gridwise serves hundreds of thousands of gig economy drivers across the United States, offering a comprehensive platform to support their unique business needs.

Lindy Biosciences, LLC is a development-stage company based in Durham, North Carolina, specializing in protein-based therapeutic formulations. Utilizing a technology known as microglassification, the company gently removes a significant portion of water from solutions of proteins and other biologics, resulting in solid, spherical, amorphous microbeads. These microbeads create stable, dense particles of therapeutic proteins suitable for various applications, including high-concentration injectable suspensions, encapsulation for controlled release, and long-term storage. Established in 2016, Lindy Biosciences aims to provide innovative solutions for the formulation of protein therapeutics, addressing the needs of medical researchers in developing advanced therapeutic options.

Edge Case Research is a company based in Pittsburgh, Pennsylvania, with an additional office in Unterschleißheim, Germany, specializing in developing software products and safety systems for companies involved in self-driving car technology. Founded in 2013, the firm focuses on testing vehicle software and artificial intelligence without requiring physical vehicles. Its key offerings include Hologram, a platform for identifying and addressing edge cases that challenge machine learning, and Switchboard, a cloud-based tool for automated robustness testing of complex software. The company employs Model-based Iterative System Safety Analysis to pinpoint and model safety risks in intricate systems. Additionally, Edge Case Research provides embedded software best practices assessment and training services. It serves industries such as autonomous vehicles and robotics, consumer electronics and the Internet of Things, and industrial controls and embedded systems.

Aeronics is a technology company focused on innovative solutions for oxygen storage, aiming to enhance accessibility for various users. The company offers two primary products: Everyday Oxygen and Pawprint Oxygen, both of which utilize advanced porous materials that absorb oxygen efficiently, similar to how a sponge absorbs water. This technology allows for a significant increase in the volume of oxygen that can be stored in a lightweight and portable device. Aeronics' FDA-approved device, which is designed for medical, recreational, and defense applications, was launched in 2020, highlighting the company's commitment to improving oxygen delivery and usability for its customers.

BoardBookit, Inc. develops a board portal software aimed at improving the efficiency of board meetings and communications for companies and their boards of directors. The platform, known as BoardBookit, offers secure tools that facilitate information sharing, communication, and decision-making processes. With a focus on transforming how companies organize and conduct board meetings, BoardBookit enhances the overall experience for board members. Founded in 2012 and headquartered in Pittsburgh, Pennsylvania, the company serves clients across the United States, Canada, Europe, and Australia.

Cocomama is a women-owned business that specializes in the production of fair trade and fully traceable hot cocoa and baking mixes. The company offers a range of organic cocoa products, including cocoa powders, baking mixes, and brownie thins, which are designed for creating cakes, pastries, and cookies. Cocomama sources its ingredients from countries such as the Dominican Republic, Madagascar, and Indonesia, ensuring high-quality and delicious chocolate products for its customers.

PittMoss LLC specializes in the production of sustainable gardening products, primarily offering PittMoss, a peat-free potting mix made from organic additives and recycled paper fibers. Founded in 1994 and based in Ambridge, Pennsylvania, the company serves greenhouse and nursery growers as well as home gardeners across the United States. PittMoss is designed to provide an environmentally friendly alternative to traditional sphagnum peat moss, utilizing materials that would otherwise contribute to landfill waste. In addition to its primary product, PittMoss also offers PittMoss Prime, a versatile soil amendment that can be blended with compost, existing soil mixes, or native soil. Through its innovative approach to gardening solutions, PittMoss aims to make sustainable gardening more accessible and affordable for all users.

C360 Technologies, Inc., established in 2008 and based in Wexford, Pennsylvania, specializes in manufacturing innovative video products for broadcast and over-the-top (OTT) platforms. The company offers non-stitched immersive video solutions, including cameras and workstations, that directly connect with broadcasters' backhaul systems, providing multiple live HD-SDI outputs and enhanced replay systems for real-time broadcast production. C360's products enable simultaneous live television events and 4K streaming to OTT platforms, empowering users with independent control of camera location and functions during live events.

Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

Zive, Inc. is a consumer software company based in New York, specializing in productivity applications for both business and professional users. Founded in 2013, the company is best known for its flagship product, Kiwi for Gmail, an email desktop application designed for Mac and Windows that integrates Google’s Workspace suite into a user-friendly desktop experience. The latest version, Kiwi for Gmail 2.0, features a new toolbar that enhances multitasking capabilities. With broad adoption among over 600 large enterprises and small to medium-sized businesses utilizing Google Workspace, Zive is committed to further developing innovative productivity applications to meet the needs of its users.

Anglr is a company dedicated to enhancing the sportfishing experience through a vertical social app and a connected suite of IoT devices. Targeting the $50 billion sportfishing industry, Anglr offers an advanced fishing application that serves as a digital logbook for anglers. This application allows users to track essential details of their fishing trips, such as cast locations, bait used, weather conditions, and catch counts. By recording and reviewing these statistics, users can not only relive their fishing adventures but also improve their skills and share experiences with friends. The Anglr ecosystem combines technology and social interaction to create a comprehensive platform for fishing enthusiasts.

RendrFX, Inc. is a Pennsylvania-based company that specializes in mobile-first video creation software, allowing businesses and consumers to easily produce high-definition videos with motion graphics elements. Founded in 2015, RendrFX offers a software-as-a-service (SaaS) platform that connects users with a global community of computer graphics artists. This platform empowers both individuals and advertising agencies to create professional videos affordably, enhancing their online presence. By providing a user-friendly interface and curated video designs, RendrFX facilitates the video production process while also promoting a fair marketplace for motion graphics artists to showcase and sell their work.

Cognition Therapeutics, Inc. is a clinical-stage neuroscience company based in Pittsburgh, Pennsylvania, dedicated to developing small-molecule therapeutics for neurodegenerative and neuro-ophthalmic disorders. Established in 2007, the company focuses on addressing the underlying cellular damage caused by toxic proteins associated with diseases such as Alzheimer's and dry age-related macular degeneration. Its lead product candidate, CT1812, is an oral drug designed to penetrate the blood-brain barrier and selectively target the S2R complex, aiming to restore normal cellular processes disrupted by these conditions. Cognition Therapeutics combines biological expertise with proprietary assays and medicinal chemistry to create innovative and effective drug candidates for age-related degenerative diseases affecting the central nervous system and retina.

PittMoss LLC specializes in the production of sustainable gardening products, primarily offering PittMoss, a peat-free potting mix made from organic additives and recycled paper fibers. Founded in 1994 and based in Ambridge, Pennsylvania, the company serves greenhouse and nursery growers as well as home gardeners across the United States. PittMoss is designed to provide an environmentally friendly alternative to traditional sphagnum peat moss, utilizing materials that would otherwise contribute to landfill waste. In addition to its primary product, PittMoss also offers PittMoss Prime, a versatile soil amendment that can be blended with compost, existing soil mixes, or native soil. Through its innovative approach to gardening solutions, PittMoss aims to make sustainable gardening more accessible and affordable for all users.

Rinovum Women's Health, Inc. develops medical devices for women. It offers Stork, a medical device that aids in natural fertility and conception in the privacy of home.

Wombat Security Technologies, Inc. specializes in interactive software solutions aimed at enhancing cyber security awareness and compliance among employees. The company offers a comprehensive Security Education Platform that includes knowledge assessments, a library of simulated attacks, and interactive training modules designed to significantly reduce the success rate of phishing attacks and malware infections. Key products include PhishPatrol, an anti-phishing email filter; PhishAlarm Analyzer, which assists in identifying reported phishing emails; CyberStrength, an assessment tool for evaluating employee cyber security knowledge; and various simulation services such as USBGuru and SmishGuru that train employees on memory device and text message phishing attacks respectively. Wombat serves a diverse clientele, including Fortune 1000 companies in sectors such as finance, healthcare, and technology. Founded in 2008 and based in Pittsburgh, Pennsylvania, with an additional office in the United Kingdom, Wombat operates as a subsidiary of Proofpoint, Inc.

Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

Gemmus Pharma Inc. is a biotechnology company based in San Francisco, California, founded in 2007. The company focuses on developing therapeutics for the treatment of influenza and other infectious diseases. Its lead candidates include GP1001, a non-peptidic eicosanoid analog designed for serious influenza infections that may require hospitalization, and GP1681, which aims to alleviate influenza symptoms by reducing the exaggerated cytokine response induced by the virus. GP1001 can be used as a stand-alone treatment or in combination with antiviral drugs such as oseltamivir. Gemmus Pharma has received support from the National Institute of Allergy and Infectious Disease and has plans to file an investigational new drug application with the FDA to advance its influenza treatment initiatives.

Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies aimed at addressing unmet medical needs for patients globally. The company's flagship technology, known as Electrical Nerve Block, targets chronic pain conditions, including neuroma and residual limb pain, chronic post-surgical pain, and chronic migraine. Neuros Medical also offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and associated external devices. Established in 2008, the company is dedicated to advancing innovative solutions for pain management.

ALung Technologies, Inc., established in 1997 and based in Pittsburgh, Pennsylvania, specializes in developing and manufacturing medical devices for treating acute respiratory failure. The company's primary product is the Hemolung Respiratory Assist System, a dialysis-like device that removes carbon dioxide and delivers oxygen directly to the blood, allowing patients' lungs to rest and heal while avoiding intubation and facilitating protective ventilation.

Physcient, Inc. is a manufacturer of surgical instruments, specializing in the Differential Dissector, which is designed for blunt dissection. This device is utilized in various surgical fields, including plastic surgery and general surgery procedures such as thoracic, gastrointestinal, gynecological, urological, peripheral vascular, and orthopedic surgeries. Founded in 2007 and headquartered in Durham, North Carolina, Physcient focuses on developing modern technology for hand-held surgical instruments that facilitate quicker recovery without altering existing surgical techniques. The company's founders bring over 75 years of combined experience in advancing technologies within the life and health sciences.

Cryothermic Systems is an American medical device company focused on developing innovative products aimed at improving patient outcomes and preventing brain damage. The company's flagship product, Excel Cryo, is designed to lower brain temperature immediately following neurologic injury. This device operates without the need for electrical power or refrigeration, making it suitable for various settings, including emergency medical services and intensive care units. By utilizing a cooling collar that holds a pack in place, the device effectively extracts heat from blood vessels in the neck, facilitating cooling for patients suffering from conditions such as cardiac arrest, heart attack, stroke, and traumatic brain injury. Through its technology, Cryothermic Systems aims to enhance the care of patients experiencing critical health events.

Gemmus Pharma Inc. is a biotechnology company based in San Francisco, California, founded in 2007. The company focuses on developing therapeutics for the treatment of influenza and other infectious diseases. Its lead candidates include GP1001, a non-peptidic eicosanoid analog designed for serious influenza infections that may require hospitalization, and GP1681, which aims to alleviate influenza symptoms by reducing the exaggerated cytokine response induced by the virus. GP1001 can be used as a stand-alone treatment or in combination with antiviral drugs such as oseltamivir. Gemmus Pharma has received support from the National Institute of Allergy and Infectious Disease and has plans to file an investigational new drug application with the FDA to advance its influenza treatment initiatives.

Voci specializes in advanced speech recognition technology that transforms voice data into actionable insights for businesses. By employing AI and deep learning algorithms, Voci delivers highly accurate transcriptions and provides valuable insights related to gender, sentiment, emotion, and speaker biometrics. Their solutions are particularly beneficial for companies in regulated industries, enabling them to ensure compliance and monitor call center agents effectively. Voci's technology also generates readable automatic speech-to-text outputs for telecommunications, enhancing customer interactions. Ultimately, Voci helps organizations improve customer experiences, optimize contact center efficiency, and manage risks associated with fraud and compliance violations.

Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

Voci specializes in advanced speech recognition technology that transforms voice data into actionable insights for businesses. By employing AI and deep learning algorithms, Voci delivers highly accurate transcriptions and provides valuable insights related to gender, sentiment, emotion, and speaker biometrics. Their solutions are particularly beneficial for companies in regulated industries, enabling them to ensure compliance and monitor call center agents effectively. Voci's technology also generates readable automatic speech-to-text outputs for telecommunications, enhancing customer interactions. Ultimately, Voci helps organizations improve customer experiences, optimize contact center efficiency, and manage risks associated with fraud and compliance violations.

DiaKine Therapeutics, Inc. is a development-stage company focused on creating novel immune modulators aimed at treating diabetes and its complications. The company is developing therapies that have the potential to halt the progression of diabetes and reverse existing damage caused by the disease. Current projects include an adjunct therapy for islet cell transplants, which is in Phase 2 clinical trials, as well as treatments for newly diagnosed adults with type 1 diabetes, Latent Autoimmune Diabetes in Adults (LADA), and insulin-dependent type 2 diabetes. DiaKine's products are designed to possess unique immune-modulating and anti-inflammatory properties, offering a promising safety profile that addresses significant unmet medical needs in diabetes care.

TalkShoe, Inc. is a platform that facilitates user-generated live and recorded voice and audio content, enabling individuals to create, join, and listen to live group calls, discussions, and interactive podcasts. Founded in 2005 and based in Wexford, Pennsylvania, TalkShoe allows users to engage in voice and text chats on a wide array of topics, including business, sports, politics, and more. The service connects nearly 100,000 users and reaches millions of listeners through recorded Community Calls available on platforms like iTunes. Additionally, TalkShoe offers integration with various social networks, making it easy for users to promote their audio content. As of May 2016, TalkShoe operates as a subsidiary of iotum inc., focusing on providing tools for online creators, including podcast hosting and analytics.

StageMark develops and markets inflammatory diseases identification and monitoring solutions. The company's product, CB-CAPs, enables user to analyze complement products bound to various blood cell types such as erythrocytes, platelets, reticulocytes, and lymphocytes. StageMark, Inc. was founded in 2004 and is headquartered in Pittsburgh, Pennsylvania.

The SilentAlert Resident Attendant System is a product of NewCare Solutions, LLC. Located in the Pittsburgh metropolitan area, NewCare Solutions is a spinoff of medSage Technologies, LLC and was created when its founder, William Kaigler, was unable to find an effective and affordable solution to help his 85-year old mother live independently in her home. The SilentAlert Resident Attendant System became a reality after his mother was hospitalized and her sleep was continuously disrupted by an audible bed alarm for another patient.