Boston Scientific Corporation is a leading developer and manufacturer of medical devices aimed at various interventional medical specialties globally. Founded in 1979 and headquartered in Marlborough, Massachusetts, the company operates through three main segments: MedSurg, Rhythm and Neuro, and Cardiovascular. Its product portfolio includes devices for diagnosing and treating conditions related to the heart, gastrointestinal and pulmonary systems, urology, and chronic pain management. Boston Scientific is known for its innovative technologies, such as implantable cardioverter defibrillators, pacemakers, drug-eluting coronary stents, and spinal cord stimulators, which facilitate less-invasive medical procedures. The company emphasizes the importance of delivering meaningful innovation to enhance patient outcomes and provides alternatives to more invasive surgeries through its advanced medical technologies. Boston Scientific continues to expand its reach into new markets while remaining committed to improving health outcomes for patients worldwide.
Baylis Medical Company is a leading supplier of high-technology cardiology, endovascular and oncology products. Their Radio Frequency Puncture System is the world’s leading technology when it comes to creating controlled perforations in cardiac and vascular tissues. This ground breaking technology was designed for use by pediatric interventional cardiologists to treat pulmonary atresia. It is now the recognized worldwide gold standard for treating this disease. Adult interventional cardiologists use the NRG™ RF Transseptal Needle to create safe and controlled transseptal punctures. Interventional radiologists use the Radiofrequency Puncture System in combination with the RF PowerWire™ guidewire to re-canalize occluded arteries. In addition to their development efforts, Baylis Medical has a long history of importing and distributing products into the Canadian market. The company represents numerous manufacturers of cardiology, pain management, and radiology products in Canada. Baylis Medical enjoys an excellent reputation with the medical community. This reputation has been built on their commitment to offering state-of-the-art products along with exceptional service to all their customers.
DeVoro Medical is a developer of a medical device intended to restore blood flow. The company was founded in 2018 by and is based in Fremont, California.
Nectero Medical develops a novel treatment to stabilize growth and prevent rupture of mid-sized abdominal aortic aneurysms. The company was founded in 2017 and is headquartered in Dover, Delaware, United States.
Lumenis Ltd. is a prominent developer and provider of energy-based medical systems designed for minimally invasive procedures across the globe. The company operates through three main segments: Surgical, Ophthalmic, and Aesthetic. The Surgical segment specializes in surgical laser systems for urology, gynecology, and ENT applications, catering to hospitals and outpatient facilities. The Ophthalmic segment offers laser systems for retinal treatments, glaucoma, and refractive applications, supplying ophthalmic practices and hospitals. The Aesthetic segment focuses on advanced laser technologies for skin treatments and hair removal, positioning itself as a leader in aesthetic devices. Lumenis also provides essential services, including technical training for service personnel, maintenance, and logistical support for its products. Founded in 1991 and headquartered in Yokneam, Israel, Lumenis was originally known as ESC Medical Systems Ltd. before rebranding in 2001. The company emphasizes innovation in laser technology, contributing significantly to advancements in both medical and aesthetic fields.
Preventice Solutions, Inc. is a provider of healthcare solutions specializing in mobile health technologies and services. Founded in 2007 and based in Eagan, Minnesota, the company offers a range of platforms, including the PatientCare Portal for real-time patient data management, the PatientView Portal for healthcare organizations, and the PatientFlow Portal for monitoring centers. Preventice is known for its advanced wearable monitoring devices, such as the BodyGuardian Heart, which enhances patient mobility and compliance, and the BodyGuardian Verité, a dual-modality cardiac sensor. These technologies aim to facilitate the monitoring and management of patients with cardiac issues, improving health outcomes while potentially reducing the cost of care. The company was formed through the merger of Preventice Services and Preventice Technologies in 2014, and it operates additional offices in Fargo, North Dakota, San Francisco, California, and Houston, Texas.
Farapulse, Inc. develops and commercializes catheter-based tools specifically designed for the treatment of atrial fibrillation. Founded in 2012 and based in Menlo Park, California, the company offers an innovative product known as FARAWAVE, which utilizes advanced tissue-selective pulsed field ablation (PFA) therapy. This therapy is available on both catheter and surgical platforms for endocardial and epicardial applications. Farapulse's product range includes various catheter types, such as over-the-wire, deflectable, linear, and circumferential lesion catheters, which enable doctors to isolate pulmonary veins safely and effectively. The company's mission is to enhance the safety, speed, accessibility, and affordability of atrial fibrillation ablation for patients worldwide.
Preventice Solutions, Inc. is a provider of healthcare solutions specializing in mobile health technologies and services. Founded in 2007 and based in Eagan, Minnesota, the company offers a range of platforms, including the PatientCare Portal for real-time patient data management, the PatientView Portal for healthcare organizations, and the PatientFlow Portal for monitoring centers. Preventice is known for its advanced wearable monitoring devices, such as the BodyGuardian Heart, which enhances patient mobility and compliance, and the BodyGuardian Verité, a dual-modality cardiac sensor. These technologies aim to facilitate the monitoring and management of patients with cardiac issues, improving health outcomes while potentially reducing the cost of care. The company was formed through the merger of Preventice Services and Preventice Technologies in 2014, and it operates additional offices in Fargo, North Dakota, San Francisco, California, and Houston, Texas.
SetPoint Medical Corporation, a clinical-stage bioelectronic medicine company, develops implantable neuromodulation devices for treating patients with debilitating inflammatory diseases. SetPoint Medical Corporation was formerly known as Innovative Metabolics Inc. and changed its name to SetPoint Medical Corporation in July 2008. The company was incorporated in 2006 and is based in Valencia, California.
Saluda Medical Pty Ltd., established in 2013 and headquartered in Artarmon, Australia, focuses on developing innovative medical devices for the neuromodulation industry. The company's flagship product, Evoke, is an investigational closed-loop spinal cord stimulation system designed to measure and adapt to the spinal cord's response to stimulation. By adjusting the stimulation on every pulse, Evoke aims to optimize therapeutic outcomes for patients within their individualized treatment parameters. Saluda Medical's foundation is built on years of research from Australia's NICTA and is supported by a team of experienced engineers, clinicians, and professionals dedicated to advancing medical technologies. The company also has offices in Bloomington, Minnesota, and Harrogate, United Kingdom.
InterVene, Inc. is a medical device company based in South San Francisco, California, focused on developing innovative catheter-based therapies for chronic venous insufficiency (CVI) caused by deep vein valve failure. Founded in 2011, InterVene aims to transform the treatment of severe venous disease in the legs by introducing a novel, non-implantable catheter approach that enables physicians to create new vein valves. This technology addresses a significant unmet need for patients suffering from painful venous stasis ulcers and other debilitating symptoms associated with deep vein reflux. By providing an effective therapy for CVI, InterVene seeks to improve the quality of life for millions of Americans affected by this condition.
Pulmonx Corporation is a medical technology company focused on developing minimally invasive devices for diagnosing and treating chronic obstructive pulmonary disease (COPD), particularly severe emphysema. The company offers key products including the Zephyr Endobronchial Valve, which addresses hyperinflation in adult patients, and the Chartis Pulmonary Assessment System, a tool that evaluates collateral ventilation through flow and pressure measurements. Additionally, Pulmonx provides the StratX Lung Analysis Platform, a cloud-based service that utilizes computed tomography to analyze lung conditions, aiding in the identification of treatment targets for the Zephyr Valve. With a strong clinical foundation supported by numerous published studies, Pulmonx has received regulatory recognition, including FDA approval for its Zephyr Valve, which is now used by physicians in over 25 countries. The company aims to enhance the quality of life for emphysema patients worldwide, having facilitated the treatment of more than 19,000 patients with over 76,000 valves deployed. Founded in 1995 and headquartered in Redwood City, California, Pulmonx continues to lead in interventional procedures for COPD treatment.
VertiFlex, Inc., a medical device company, provides minimally invasive and motion preserving spinal surgery technologies in the United States and internationally. The company offers superion interspinous spacer, a percutaneous titanium implant that fits between the spinous processes in the lumbar spine. Its Superion is a motion-preserving interspinous spacer for the treatment of moderate spinal stenosis.
Vertiflex Inc was founded in 2005 and is headquartered in California, USA.
Founded in 1984, BTG plc is a corporate firm based in London, United Kingdom. The firm is a healthcare company which focuses on Interventional Medicine.
SpaceOAR is a privately held medical device company developing in-situ formed, space-filling hydrogels specifically for radiation oncology and cancer surgery indications. Its hydrogel is clinically proven to minimize side effects and protect the quality of life for prostate cancer patients undergoing radiation therapy that enables healthcare providers to minimize urinary, sexual, and bowel side effects of the patients. It was founded in 2007 and is headquartered in Bedford, Massachusetts.
VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.
Claret Medical, Inc. is a cardiovascular medical device company that specializes in developing cerebral vascular protection systems for transcatheter aortic valve implantation and various endovascular procedures. Its flagship product, the Claret Medical Sentinel Cerebral Protection System, is a percutaneously delivered embolic protection device designed to capture and remove debris that may be dislodged during these procedures. Additionally, the company offers small 6 French catheters that are inserted through an artery in the patient's right arm and guided toward the heart, facilitating the protection of the cerebral vascular system from potential embolic material. Founded in 2009 and based in Santa Rosa, California, Claret Medical operates as a subsidiary of Boston Scientific Corporation, focusing on enhancing patient safety during interventional cardiovascular treatments.
Cryterion Medical has developing a single-shot cryoablation platform for the treatment of atrial fibrillation (AF). Cryterion is headquartered in Carlsbad, California, with offices in Montreal, Canada and Wexford, Ireland. The Cryterion Medical cryoablation platform uses cryothermal energy to interrupt the irregular electrical signals that can cause AF. Developed with a next-generation balloon catheter, advanced mapping catheter, steerable sheath and enhanced console, the system is designed to streamline overall procedural workflow, enhance maneuverability and improve positioning in challenging anatomy.
RenovoRx, Inc. is a medical device company based in Los Altos, California, focused on developing innovative solutions for the targeted delivery of therapeutic and diagnostic agents to specific sites in the peripheral vascular system. Founded in 2012, the company has created the RenovoCath, an endovascular catheter designed for use in the visceral and peripheral vascular systems. RenovoRx has received FDA clearance for its RenovoCath RC120 and is actively introducing this technology to the clinical market. The company aims to enhance treatment outcomes for cancer patients through its proprietary Trans-Arterial Micro-Perfusion therapy platform, which strategically targets tumors while potentially reducing the side effects associated with traditional systemic therapies. Supported by a knowledgeable Board of Directors and an Advisory Board comprising interventional radiologists, surgical oncologists, and gastroenterologists, RenovoRx is committed to advancing its clinical development strategies and addressing significant unmet medical needs.
NVISION MEDICAL Corporation operates in the healthcare sector. The company was incorporated in 2009 and is based in Saratoga, California.
nVision is a privately-held medical device company dedicated to filling the void in women’s health innovation.
Since its founding in 2011, the company has relentlessly focused on developing devices to enable clinicians to assess the health of previously inaccessible parts of the female reproductive tract.
Securus Medical Group
Acquisition in 2018
Securus Medical Group engages in the development of clinical tools to improve the safety and efficacy of ablation therapy by providing real-time, non-contact, high-resolution tissue temperature monitoring, and mapping products. The company engages in developing real-time, noncontact, thermal mapping systems to determine intrabody tissue temperatures.
NxThera develops medical technologies to treat a variety of endourology conditions, including BPH. The company's technology platform utilizes a simple, minimally invasive, vapor therapy designed to measurably improve urinary flow and patient quality of life. BPH afflicts more than 32 million men in the United States.
EMcision is a medical device company committed to improving the lives of cancer patients. It provides Habib EndoHPB, an endoscopic bipolar RF probe developed to ablate tissue in the gastro-intestinal tract; Habib Endoblate, a bipolar RF probe that is particularly effective for performing endoluminal ablation of gastrointestinal tumours that are not suitable for surgical resection; Habib VesCoag, an endovascular RF catheter that is particularly effective for precise vascular occlusion.
Millipede Inc. develops percutaneous solutions for mitral valve repair. The company was incorporated in 2012 and is based in Santa Rosa, California. As of January 29, 2019, Millipede Inc. operates as a subsidiary of Boston Scientific Corporation.
Millipede Inc. develops percutaneous solutions for mitral valve repair. The company was incorporated in 2012 and is based in Santa Rosa, California. As of January 29, 2019, Millipede Inc. operates as a subsidiary of Boston Scientific Corporation.
Apama Medical, Inc. manufactures catheter ablation technology devices for the treatment of atrial fibrillation (AF). Its product, include Apama radiofrequency (RF) balloon catheter system, a single-shot, multi-electrode technology which is designed to combine the benefits of both RF point-by-point and balloon-based ablation approaches. Its technology incorporates built-in digital cameras with LED lights and sensing electrodes on the balloon which allow for real-time visualization and assessment of catheter electrode contact. The company was incorporated in 2009 and is based in Campbell, California. As of October 10, 2017, Apama Medical, Inc. operates as a subsidiary of Boston Scientific Corporation.
SetPoint Medical Corporation, a clinical-stage bioelectronic medicine company, develops implantable neuromodulation devices for treating patients with debilitating inflammatory diseases. SetPoint Medical Corporation was formerly known as Innovative Metabolics Inc. and changed its name to SetPoint Medical Corporation in July 2008. The company was incorporated in 2006 and is based in Valencia, California.
Channel Medsystems, Inc. is a clinical-stage medical technology company focused on developing advanced solutions for women's healthcare, specifically in the area of endometrial ablation. Founded in 2009 and based in Emeryville, California, the company specializes in proprietary cryo-ablation delivery technologies. Its innovative approach combines cryothermic energy with a user-friendly, self-contained handheld device, eliminating the need for separate control units or additional capital equipment. This design aims to enhance the treatment experience for female patients while meeting the high standards expected by healthcare providers.
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies to address unmet medical needs for patients globally. The company’s flagship technology, Electrical Nerve Block, targets the elimination of chronic pain associated with various conditions, including neuroma, residual limb pain, chronic post-surgical pain, and chronic migraines. Additionally, Neuros Medical offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices designed to enhance treatment outcomes. Founded in 2008, the company aims to provide innovative solutions for chronic pain management.
Amphora Medical is a Minnesota-based developer of medical devices and instruments. The company is currently working on a novel cystoscopic device that has the potential to improve bladder function and quality of life for people with Overactive Bladder Syndrome (OAB). It was founded in 2011 and is headquartered in Minneapolis, Minnesota, United States.
NeuroTronik
Series B in 2017
NeuroTronik, spun out of medical technology incubator Synecor, is developing a medical device that could take the place of drugs currently used to heart failure. Read more about the company's technology,
Symetis is a Swiss company based in Ecublens that specializes in developing innovative minimally invasive heart valve replacement therapies for patients with heart valve diseases, particularly aortic valve stenosis. The company focuses on enhancing patient care and safety by providing simple and accurate solutions for heart valve replacement. Its proprietary Acurate Aortic Valve Replacement System features a distinctive self-positioning design, which facilitates easy implant positioning and alignment, thereby improving the overall ease of use for healthcare providers. Through its advanced transcatheter aortic valve implantation devices, Symetis aims to address severe cardiac valve conditions and enhance treatment options within the healthcare industry.
Pulmonx Corporation is a medical technology company focused on developing minimally invasive devices for diagnosing and treating chronic obstructive pulmonary disease (COPD), particularly severe emphysema. The company offers key products including the Zephyr Endobronchial Valve, which addresses hyperinflation in adult patients, and the Chartis Pulmonary Assessment System, a tool that evaluates collateral ventilation through flow and pressure measurements. Additionally, Pulmonx provides the StratX Lung Analysis Platform, a cloud-based service that utilizes computed tomography to analyze lung conditions, aiding in the identification of treatment targets for the Zephyr Valve. With a strong clinical foundation supported by numerous published studies, Pulmonx has received regulatory recognition, including FDA approval for its Zephyr Valve, which is now used by physicians in over 25 countries. The company aims to enhance the quality of life for emphysema patients worldwide, having facilitated the treatment of more than 19,000 patients with over 76,000 valves deployed. Founded in 1995 and headquartered in Redwood City, California, Pulmonx continues to lead in interventional procedures for COPD treatment.
Neovasc Inc., a specialty medical device company, develops, manufactures, and markets medical devices for cardiovascular marketplace in Europe, the United States, and internationally. Its products include the Tiara technology for the transcatheter treatment of mitral valve disease; and the Neovasc Reducer for the treatment of refractory angina. The company was formerly known as Medical Ventures Corp. and changed its name to Neovasc Inc. in July 2008. Neovasc Inc. was incorporated in 2000 and is headquartered in Richmond, Canada.
The LumenR Tissue Retractor System
Acquisition in 2016
The LumenR Tissue Retractor System is currently in development for use during endoscopic resection of lesions in the colon, esophagus or stomach.
ECPM is a medical device company focused on designing and commercializing a platform of products and services for gastrointestinal caregivers. The Company offers a range of products and services that span single-use devices and infection control products, pathology, and imaging systems. Its products are used in colonoscopy and procedures of the upper GI tract, including esophagogastroduodenoscopy (EGD).
The company is headquartered in Alpharetta, Georgia.
Securus Medical Group
Series C in 2016
Securus Medical Group engages in the development of clinical tools to improve the safety and efficacy of ablation therapy by providing real-time, non-contact, high-resolution tissue temperature monitoring, and mapping products. The company engages in developing real-time, noncontact, thermal mapping systems to determine intrabody tissue temperatures.
Cosman Medical offers a comprehensive range of radiofrequency (RF) generators, electrodes, and cannulae for neurosurgery and pain management in interventional anesthesiology and podiatry. Radiofrequency (RF) nerve ablation is a versatile medical technology with a 60-year track record in medicine. It can be used to treat chronic back and neck pain, including pain from facet joint dysfunction, lumbago, sciatica, nerve impingement, intervertebral disc dysfunction, sacroiliac joint dysfunction, headaches, postoperative pain, complex regional pain syndrome (CRPS), reflex sympathetic dystrophy (RSD). It can also be used to treat severe, intractable pain such as that arising from end-stage cancer (cordotomy), nerve root avulsion injury (DREZ and DREZ nucleus caudalis), and trigeminal neuralgia (PSR). In podiatry, RF is used to treat intractable pain from foot, heel, and ankle disorders like plantar fasciitis and Morton's Neuroma. In functional neurosurgery, RF can be used to treat movement disorders such as Parkinson's Disease, essential tremor, and spasticity.
NxThera develops medical technologies to treat a variety of endourology conditions, including BPH. The company's technology platform utilizes a simple, minimally invasive, vapor therapy designed to measurably improve urinary flow and patient quality of life. BPH afflicts more than 32 million men in the United States.
TVA Medical, Inc. is a medical device company based in Austin, Texas, that specializes in the development and manufacture of catheter-based equipment and solutions aimed at treating end-stage renal disease (ESRD) and peripheral vascular diseases. Founded in 2009, TVA Medical focuses on creating innovative and minimally invasive therapies to improve patient outcomes. The company has garnered funding from Santé Ventures and operates as a subsidiary of Becton, Dickinson and Company since July 2018.
Channel Medsystems, Inc. is a clinical-stage medical technology company focused on developing advanced solutions for women's healthcare, specifically in the area of endometrial ablation. Founded in 2009 and based in Emeryville, California, the company specializes in proprietary cryo-ablation delivery technologies. Its innovative approach combines cryothermic energy with a user-friendly, self-contained handheld device, eliminating the need for separate control units or additional capital equipment. This design aims to enhance the treatment experience for female patients while meeting the high standards expected by healthcare providers.
SetPoint Medical Corporation, a clinical-stage bioelectronic medicine company, develops implantable neuromodulation devices for treating patients with debilitating inflammatory diseases. SetPoint Medical Corporation was formerly known as Innovative Metabolics Inc. and changed its name to SetPoint Medical Corporation in July 2008. The company was incorporated in 2006 and is based in Valencia, California.
American Medical Systems, a wholly owned subsidiary of Endo Pharmaceutical headquartered in Minnetonka, Minn., is a diversified supplier of medical devices and procedures to cure incontinence, erectile dysfunction, benign prostatic hyperplasia (BPH), pelvic floor prolapse and other pelvic disorders in men and women. These disorders can significantly diminish oneâ€:tm:s quality of life and profoundly affect social relationships. In recent years, the number of people seeking treatment has increased markedly as a result of longer lives, higher quality-of-life expectations and greater awareness of new treatment alternatives. American Medical Systemsâ€:tm: products reduce or eliminate the incapacitating effects of these diseases, often through minimally invasive therapies. The companyâ€:tm:s products were used to treat more than 340,000 patients in 2010.
Preventice Solutions, Inc. is a provider of healthcare solutions specializing in mobile health technologies and services. Founded in 2007 and based in Eagan, Minnesota, the company offers a range of platforms, including the PatientCare Portal for real-time patient data management, the PatientView Portal for healthcare organizations, and the PatientFlow Portal for monitoring centers. Preventice is known for its advanced wearable monitoring devices, such as the BodyGuardian Heart, which enhances patient mobility and compliance, and the BodyGuardian Verité, a dual-modality cardiac sensor. These technologies aim to facilitate the monitoring and management of patients with cardiac issues, improving health outcomes while potentially reducing the cost of care. The company was formed through the merger of Preventice Services and Preventice Technologies in 2014, and it operates additional offices in Fargo, North Dakota, San Francisco, California, and Houston, Texas.
Xlumena, Inc. develops image-guided therapeutic endoscopy products for the field of medicine. It provides AXIOS Stent and Delivery System, a stent for the treatment of pancreatic pseudocysts; and NAVIX Access Device for the treatment of pancreatic pseudocysts. Xlumena, Inc. was formerly known as Novatech, Inc. The company was founded in 2008 and is based in Mountain View, California. As of April 2, 2015, Xlumena, Inc. operates as a subsidiary of Boston Scientific Corporation.
InterVene, Inc. is a medical device company based in South San Francisco, California, focused on developing innovative catheter-based therapies for chronic venous insufficiency (CVI) caused by deep vein valve failure. Founded in 2011, InterVene aims to transform the treatment of severe venous disease in the legs by introducing a novel, non-implantable catheter approach that enables physicians to create new vein valves. This technology addresses a significant unmet need for patients suffering from painful venous stasis ulcers and other debilitating symptoms associated with deep vein reflux. By providing an effective therapy for CVI, InterVene seeks to improve the quality of life for millions of Americans affected by this condition.
Iogyn, Inc. is a medical device start-up company located in Cupertino, California. The Company has developed the Symphion System, designed for endoscopically-controlled Radiofrequency bi-polar resection and removal of soft tissue, such as polyps, myomas and prostate adenomas, requiring endoscopic visualization under continuous flow conditions.
StarMedTec is an internationally established manufacturer of medical laser systems. With its laser surgery solutions, it covers the medical disciplines of urology, gynecology, gastroenterology, ENT, pneumology, and general surgery.
Sensible Medical Innovation Ltd develops medical radar monitoring and imaging technology solutions. The company offers ReDS, a solution for monitoring and management of lung fluid in patients with heart failure and other fluid management problems. Sensible Medical Innovation Ltd was founded in 2007 and is based in Netanya, Israel.
SetPoint Medical Corporation, a clinical-stage bioelectronic medicine company, develops implantable neuromodulation devices for treating patients with debilitating inflammatory diseases. SetPoint Medical Corporation was formerly known as Innovative Metabolics Inc. and changed its name to SetPoint Medical Corporation in July 2008. The company was incorporated in 2006 and is based in Valencia, California.
BaroSense is committed to develop and commercialize novel anti-obesity products that provide a meaningful contribution to this leading healthcare problem facing the United States today. BaroSense was conceived in order to create a safe, simple, effective, and minimally invasive alternative to the surgical treatment of obesity - an innovative approach to assist those people who need help beyond traditional diets, and who wish to avoid extensive, irreversible surgery.
Bard Electrophysiology, a division of C. R. Bard, Inc., specializes in the development and delivery of devices for diagnosing and treating cardiac arrhythmias. With a comprehensive product portfolio, the company provides advanced radiofrequency (RF) ablation and mapping catheters, diagnostic catheters, and computer-based electrophysiology mapping and recording systems. Additionally, Bard Electrophysiology offers temporary pacing electrodes and vascular/cardiac access devices. Through its commitment to innovation and education, Bard Electrophysiology has established itself as a leader in the electrophysiology field, supporting healthcare providers in managing complex cardiac conditions.
Channel Medsystems, Inc. is a clinical-stage medical technology company focused on developing advanced solutions for women's healthcare, specifically in the area of endometrial ablation. Founded in 2009 and based in Emeryville, California, the company specializes in proprietary cryo-ablation delivery technologies. Its innovative approach combines cryothermic energy with a user-friendly, self-contained handheld device, eliminating the need for separate control units or additional capital equipment. This design aims to enhance the treatment experience for female patients while meeting the high standards expected by healthcare providers.
BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and based in Goleta, California. The company specializes in developing non-surgical and non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is designed to be inserted into the stomach through the mouth via a simple endoscopic procedure. This device helps patients feel full more quickly, prolongs the sensation of fullness, and delays gastric emptying, thereby supporting weight loss efforts.
Vessix Vascular, Inc. (formerly known as Minnow Medical, Inc.). Vessix is a privately-held pre-revenue stage company developing novel radiofrequency balloon catheter technology. The Company's initial product, the ZCath® System, has a CE Mark for use in reducing plaque in peripheral leg arteries.
Rhythmia Medical, Inc., an early stage medical device company, develops medical devices for the treatment of cardiac arrhythmia. It focuses on developing a 3D mapping system to enable an improvement in the catheter ablation procedures used to treat tachy-arrhythmias, such as atrial fibrillation.
BridgePoint Medical, a private company with headquarters in Minneapolis, Minnesota, is focused on developing innovative and proprietary technology in the field of interventional cardiology for access to and treatment of chronic total occlusions.
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies to address unmet medical needs for patients globally. The company’s flagship technology, Electrical Nerve Block, targets the elimination of chronic pain associated with various conditions, including neuroma, residual limb pain, chronic post-surgical pain, and chronic migraines. Additionally, Neuros Medical offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices designed to enhance treatment outcomes. Founded in 2008, the company aims to provide innovative solutions for chronic pain management.
Cameron Health, Inc. is a development stage medical device company focused on creating advanced implantable electronic devices. The company specializes in the development of the subcutaneous implantable defibrillator (S-ICD) system, designed to protect patients from sudden cardiac arrest. By leveraging state-of-the-art technologies and a team of experienced professionals, Cameron Health aims to address complex medical challenges and provide innovative treatment options that have been previously unattainable with existing therapies.
Revascular Therapeutics
Acquisition in 2011
Revascular Therapeutics is a medical device company that develops solutions for the intravascular treatment of complex lesions and total occlusions. Revascular develops percutaneous medical devices to reopen occluded vessels.
Atritech is a private company located in Minneapolis, Minnesota. The company was founded in 2000 and has developed proprietary technology focused on replacing long term anticoagulation therapy for patients with non-valvular atrial fibrillation at risk of stroke. The first implants of the WATCHMAN® Left Atrial Appendage Closure Technology were performed in Germany in August of 2002 and in the United States in October of 2003. Since then the company has conducted a large randomized clinical trial comparing the WATCHMAN® Left Atrial Appendage Closure Technology to long term Warfarin therapy in patients with non-valvular atrial fibrillation at risk of stroke. The WATCHMAN® Device is CE Marked and available in many markets outside the United States. The WATCHMAN® Device is currently available For Investigational Use Only in the United States.
IntElect Medical, Inc., an early stage medical device company, develops and commercializes deep brain stimulation (DBS) therapies and technology for patients suffering with disabilities from stroke and traumatic brain injury. The company focuses on developing an implantable neuromodulation system for stroke and traumatic brain injury recovery.
Sadra Medical is dedicated to creating innovative, minimally invasive alternatives to traditional surgical valve replacement, specifically targeting the treatment of aortic valve disease. The company aims to address the significant clinical need for effective therapies, as aortic valve stenosis affects approximately 3 million individuals in the United States, yet only a small percentage receive treatment through conventional open-heart surgery. By developing new devices that facilitate these advanced procedures, Sadra Medical seeks to enhance patient care and make valve replacement accessible to a broader range of patients. The company's goal is to reduce the risks and complications associated with open surgical procedures, providing a viable therapeutic option for those who currently lack effective treatment.
Asthmatx, Inc., a medical device company, focuses on developing and commercializing a therapeutic treatment for asthma in the United States. The company has developed a technology that is designed to deliver controlled thermal energy to the airways of adult patients to reduce the mass of airway smooth muscle in a procedure called Bronchial Thermoplasty. Asthmatx offers an interventional medical device, called the Alair System, for the bronchoscopic treatment of patients with moderate to severe asthma. Asthmatx was founded in 2003 and is headquartered in Mountain View, California. As of October 26, 2010, Asthmatx operates as a wholly-owned subsidiary of [Boston Scientific](/organization/boston-scientific).
Sadra Medical is dedicated to creating innovative, minimally invasive alternatives to traditional surgical valve replacement, specifically targeting the treatment of aortic valve disease. The company aims to address the significant clinical need for effective therapies, as aortic valve stenosis affects approximately 3 million individuals in the United States, yet only a small percentage receive treatment through conventional open-heart surgery. By developing new devices that facilitate these advanced procedures, Sadra Medical seeks to enhance patient care and make valve replacement accessible to a broader range of patients. The company's goal is to reduce the risks and complications associated with open surgical procedures, providing a viable therapeutic option for those who currently lack effective treatment.
IntElect Medical, Inc., an early stage medical device company, develops and commercializes deep brain stimulation (DBS) therapies and technology for patients suffering with disabilities from stroke and traumatic brain injury. The company focuses on developing an implantable neuromodulation system for stroke and traumatic brain injury recovery.
Cameron Health, Inc. is a development stage medical device company focused on creating advanced implantable electronic devices. The company specializes in the development of the subcutaneous implantable defibrillator (S-ICD) system, designed to protect patients from sudden cardiac arrest. By leveraging state-of-the-art technologies and a team of experienced professionals, Cameron Health aims to address complex medical challenges and provide innovative treatment options that have been previously unattainable with existing therapies.
CryoCor, Inc. is a medical technology company headquartered in San Diego, California developing products that use cryogenic technology to treat cardiac rhythm disorders called arrhythmias. Cardiac cryoablation is a non-surgical, minimally-invasive procedure in which a cardiologist inserts a catheter into a blood vessel in the leg of an afflicted individual and advances it into the heart. Once it reaches the targeted cardiac tissue, the catheter tip temperature is lowered to approximately -90°C — thereby blocking the conduction of the abnormal signals causing the heart to beat inappropriately and restoring its function to normal. The CryoCor™ Cardiac Cryoablation System consists of a cryoablation catheter that is connected to an articulating arm mounted on the company’s refrigeration console. To facilitate catheter placement, the System can be used in conjunction with CryoCor introducer sheaths. The System has been approved for use in Europe and has been commercially available there since 2002. CryoCor's European activities are managed by its wholly-owned subsidiary in Cologne, Germany which directs the company's marketing, sales and post-market clinical activities. The CryoCor Cardiac Cryoablation System is currently in use at multiple medical centers throughout Europe.
Remon Medical Technologies is a development-stage company focused on communication technology for medical device applications. It offers RemonCHF, a device that monitors the hemodynamic status of patients with congestive heart failure; and RemonAAA, a device that monitors pressure following an endograft procedure in AAA patients. The company is based in Caesarea, Israel.
IntElect Medical, Inc., an early stage medical device company, develops and commercializes deep brain stimulation (DBS) therapies and technology for patients suffering with disabilities from stroke and traumatic brain injury. The company focuses on developing an implantable neuromodulation system for stroke and traumatic brain injury recovery.
Orqis Medical
Series D in 2007
ORQIS Medical Corporation operates as a medical device company. It develops and sells minimally invasive devices for improving cardiac performance through aortic flow therapy. It offers Cancion System, a heart failure treatment that uses continuous aortic flow augmentation technology to improve symptoms of heart failure and change the underlying course of the disease for patients hospitalized for de-compensated heart failure. The company’s products also include Exeleras System to treat chronic heart failure patients.
EndoTex Interventional Systems, Inc., a development stage medical device company, engages in the development and manufacture of less-invasive medical devices for use in the vascular system. It provides solutions for treating carotid artery disease. The company was founded in 1995 and is based in Cupertino, California. As of January 4, 2007, EndoTex Interventional Systems, Inc. is a subsidiary of Boston Scientific Corp.
Health Hero Network, Inc. develops and markets technology solutions for remote health monitoring and management. The company provides health management programs delivering personalized daily monitoring and patient education, and information to care providers. It also offers Health Buddy system that serves as the interface between patients at home and care providers, facilitating patient education and monitoring of chronic conditions. The company's Health Buddy system includes monitoring technologies, clinical information databases, Internet-enabled decision support tools, health management programs, and content development software tools. It serves hospitals, health plans, government health organizations, disease management companies, and pharmaceutical companies or universities conducting clinical trials or studies. The company was founded in 1988 and is based in Palo Alto, California. As of December 19, 2007, Health Hero Network, Inc. operates as a subsidiary of Robert Bosch GMBH.
Sadra Medical is dedicated to creating innovative, minimally invasive alternatives to traditional surgical valve replacement, specifically targeting the treatment of aortic valve disease. The company aims to address the significant clinical need for effective therapies, as aortic valve stenosis affects approximately 3 million individuals in the United States, yet only a small percentage receive treatment through conventional open-heart surgery. By developing new devices that facilitate these advanced procedures, Sadra Medical seeks to enhance patient care and make valve replacement accessible to a broader range of patients. The company's goal is to reduce the risks and complications associated with open surgical procedures, providing a viable therapeutic option for those who currently lack effective treatment.
Solace Therapeutics, Inc. develops non-surgical office based treatments for unexpected bladder leaks in women. The company provides Vesair Bladder Control System, a non-surgical device that floats within the urinary bladder to eliminate and reduce involuntary urinary leakage. Its Vesair Bladder Control System is a non-surgical alternative to involuntary urinary leakage and a lightweight device to address the cause of stress urinary incontinence. The company was incorporated in 2002 and is based in Framingham, Massachusetts.
Cameron Health, Inc. is a development stage medical device company focused on creating advanced implantable electronic devices. The company specializes in the development of the subcutaneous implantable defibrillator (S-ICD) system, designed to protect patients from sudden cardiac arrest. By leveraging state-of-the-art technologies and a team of experienced professionals, Cameron Health aims to address complex medical challenges and provide innovative treatment options that have been previously unattainable with existing therapies.
Guidant Corporation is engaged in the design and manufacture of cardiovascular medical products. It is operating as a part off Boston Scientific and Abbott Labs, manufacturing artificial cardiac pacemakers,implantable cardioverter-defibrillators, stents, and more. Its medical devices help patients with heart diseases in returning to active and productive lives and physicians for improving patient management and clinical outcomes. Guidant Corporation is headquartered in Indianapolis, Indiana and was founded in 1994.
Cameron Health, Inc. is a development stage medical device company focused on creating advanced implantable electronic devices. The company specializes in the development of the subcutaneous implantable defibrillator (S-ICD) system, designed to protect patients from sudden cardiac arrest. By leveraging state-of-the-art technologies and a team of experienced professionals, Cameron Health aims to address complex medical challenges and provide innovative treatment options that have been previously unattainable with existing therapies.
Adiana, Inc. engages in the development and testing of transcervical sterilization system for permanent birth control. It develops Complete TCS, which consists of a radiofrequency generator, delivery catheter, and implantable matrix. The company was founded in 1997 and is based in Redwood City, California. As of March 16, 2007, Adiana, Inc. is a subsidiary of CYTYC Corp.
BrainsGate, Ltd., a medical device company, develops therapies for patients suffering from central nervous system (CNS) diseases. It offers a technology platform that involves electrical stimulation of the spheno-palatine ganglion (SPG), a nervous center known to increase cerebral blood flow. The company develops an ischemic stroke system that is based on an implantable electrode and is designed to deliver electrical stimulation to the spheno-palatine ganglion (SPG). Its system augments cerebral blood flow by using an external system temporarily attached to the patient’s cheek. BrainsGate, Ltd. was founded in 2000 and is based in Caesarea, Israel.
3F Therapeutics
Series C in 2005
3F Therapeutics develops, manufactures, and markets cardiovascular devices. It offers invasive and transapical aortic heart replacement technology, including enabling aortic heart valve, entrata aortic valve system, and endurance valve system to reduce surgical cross-clamp and cardio-pulmonary bypass time, utilization for congestive heart failure.
Advanced Stent Technologies
Acquisition in 2005
Advanced Stent Technologies designs and develops stents and stent delivery systems for the treatment of atherosclerosis at bifurcations in the coronary vasculature. The company’s flagship product, the SLK-View stent and delivery system, is used for treating diseased bifurcations by providing stability to the main artery while maintaining access to the side branch vessel. Advanced Stent Technologies was founded in 1997 and is based in Pleasanton, California.
VisionCare Ophthalmic Technologies, Inc. operates as a specialty medical device company that engages in the research, development, manufacture, and marketing of implantable ophthalmic devices, and technologies that are intended to improve vision for individuals with untreatable retinal disorders. The company offers Implantable Miniature Telescope (IMT), an implantable medical device to improve vision and quality of life in individuals with end-stage age-related macular degeneration (AMD). Its telescope implant is integral to the CentraSight treatment program, which has been developed to help patients follow the necessary steps for proper diagnosis, surgical evaluation, and postoperative care. VisionCare Ophthalmic Technologies, Inc. was founded in 1997 and is based in Saratoga, California.
Founded in 1998, REVA Medical is dedicated to developing minimally invasive medical devices that leverage the Company's proprietary biomaterial and stent technologies to improve the treatment of disease. Guided by a management team and scientific advisors with extensive product development and clinical interventional cardiology experience, REVA's initial focus is the development of an innovative drug-eluting bioresorbable coronary stent and the commencement of clinical studies that will advance the treatment of coronary artery disease.
3F Therapeutics
Series B in 2004
3F Therapeutics develops, manufactures, and markets cardiovascular devices. It offers invasive and transapical aortic heart replacement technology, including enabling aortic heart valve, entrata aortic valve system, and endurance valve system to reduce surgical cross-clamp and cardio-pulmonary bypass time, utilization for congestive heart failure.
Advanced Bionics Corporation specializes in the development and manufacture of implantable neurostimulation devices, particularly cochlear implants. Founded in 1993 and headquartered in Valencia, California, the company is dedicated to restoring hearing in individuals with hearing loss and alleviating chronic pain through its innovative technologies. In addition to its main office in California, Advanced Bionics has additional locations in Rixheim, France, and Tokyo, Japan, allowing it to serve a global market.
Broncus Technologies is a medical technology company focused on developing minimally-invasive medical devices for emphysema and other lung diseases. Broncus is investigating the Exhale emphysema product line to perform our patented treatment method called Airway Bypass. Airway Bypass could be the first minimally-invasive procedure for the treatment of homogeneous, or diffuse, emphysema, which constitutes the majority of the emphysema patient population.
Broncus is currently enrolling patients worldwide in our pivotal EASE Trial investigating a treatment of severe homogeneous emphysema.
Broncus is located in Mountain View, CA (San Francisco Bay area).
Broncus International is located in Nyon, Switzerland.
Proxima Therapeutics develops radiation delivery systems for the treatment of solid cancerous tumors, with an initial focus on brain and breast cancer. Founded in 1996, the company’s marketed products include GliaSite RTS for brain cancer and MammoSite RTS for breast cancer. Proxima Therapeutics was acquired by Cytec Industries Inc. in 2005.
Enteric Medical Technologies
Acquisition in 2002
Enteric Medical Technologies designs, manufactures, and markets minimally invasive technologies for the treatment of gastroesophageal reflux disease. It offers Enteryx implantable biopolymer, which is injected into the wall of the esophagus to reinforce the LES. The company was incorporated in 1998 and is based in Foster City, California. As of June 12, 2002, Enteric Medical Technologies, Inc. operates as a subsidiary of Boston Scientific Corporation.
BioSET, Inc., founded in 2001 and based in Rockville, Maryland, specializes in the research and development of synthetic bioactive peptides for medical applications. The company focuses on creating proprietary therapeutic peptides and implantable devices designed to enhance bone and soft tissue repair, particularly in orthobiologics. Its flagship product, Amplex, is an implantable device that combines a peptide with a synthetic ceramic scaffold, serving as a surgical bone graft implant for various spinal and orthopedic surgeries, including lumbar degenerative disc disease and foot and ankle fusion procedures. Additionally, BioSET develops products for sports medicine and offers peptide signaling molecules along with diverse scaffold biomaterials to support musculoskeletal applications, including trauma and fracture repair. As of February 2015, BioSET operates as a subsidiary of Ferring Pharmaceuticals Inc.
EndoTex Interventional Systems, Inc., a development stage medical device company, engages in the development and manufacture of less-invasive medical devices for use in the vascular system. It provides solutions for treating carotid artery disease. The company was founded in 1995 and is based in Cupertino, California. As of January 4, 2007, EndoTex Interventional Systems, Inc. is a subsidiary of Boston Scientific Corp.
Cardiac Pathways Corp
Acquisition in 2001
Cardiac Pathways Corp manufactures minimally-invasive systems used by electrophysiologists to diagnose and treat cardiac tachyarrhythmia (abnormally rapid heart rhythms), which if untreated can cause palpitations, fainting, and sudden cardiac arrest. Cardiac Pathways' products consist principally of systems for performing ablation treatment (a nonsurgical, minimally-invasive technique for neutralizing heart tissue responsible for starting or maintaining a tachyarrhythmia) and for diagnostic mapping (locating the source of the tachyarrhythmia within the heart). Cardiac Pathways was issued a U.S. patent related to its Real-time Position Management Tracking System. Founded in 1991, Cardiac Pathways is based in Sunnyvale, California. As of August 6, 2001, it was acquired by Boston Scientific Corporation.
Catheter Innovations
Acquisition in 2001
Catheter Innovations is a medical device company.
Embolic Protection
Acquisition in 2001
Embolic Protection manufactures devices for the prevention of embolic complications including stroke and heart attack during interventional vascular procedures.
Target Therapeutics
Acquisition in 1997
Target Therapeutics develops and markets disposable medical devices that are used in minimally-invasive procedures for the treatment of vascular diseases. Target Therapeutics is based in Fremont, California, United States and operates as a subsidiary of Boston Scientific Corporation.
EP Technologies
Acquisition in 1996
EP Technologies provides electrophysiology catheters and systems for use in minimally invasive procedures to diagnose and treat cardiac tachyarrhythmias. The company is based in Sunnyvale, California.