Chimerix

Chimerix, Inc. is a biopharmaceutical company based in Durham, North Carolina, focused on the development of innovative medicines for patients with cancer and serious viral infections. The company is advancing several clinical-stage programs, including dociparstat sodium (DSTAT), a glycosaminoglycan compound aimed at improving outcomes for patients with acute myeloid leukemia during chemotherapy. Another key candidate is brincidofovir (BCV), an antiviral drug being developed as a medical countermeasure for smallpox. Chimerix also leads the development of CMX001, a broad-spectrum antiviral agent targeting life-threatening double-stranded DNA viral infections, currently undergoing multiple clinical studies for use in immunocompromised patients. Additionally, CMX157, an antiviral compound with activity against HIV and hepatitis B, is in development, addressing challenges posed by existing therapies. The company collaborates with various organizations for research and commercialization, deriving revenue from licensing agreements and royalties. Founded in 2000, Chimerix is committed to transforming patient care through its advanced therapeutic candidates.

Michelle LaSpaluto

CFO, Finance

1 past transactions

Oncoceutics

Acquisition in 2021
Oncoceutics, Inc. is a clinical-stage drug discovery and development company based in Philadelphia, Pennsylvania. Founded in 2009, the company focuses on targeting potent tumor suppressor pathways in human cancer. Its lead compound, ONC201, is an orally active DRD2 small molecule antagonist that has demonstrated significant anti-tumor activity across various cancer types through a unique mechanism of action. ONC201 selectively engages apoptotic response mechanisms within tumors, allowing for a cytotoxic effect while sparing normal cells, which contributes to its favorable safety profile. The company is currently evaluating ONC201 in multiple clinical trials at leading cancer centers globally, reflecting its potential for safe and meaningful therapeutic benefits for cancer patients. Oncoceutics' strategic alliances with institutions such as the National Institutes of Health and Calvert Research, LLC, further support its mission to advance innovative cancer treatments.
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