Fondazione Biotecnopolo di Siena
Grant in 2025
Fondazione Biotecnopolo di Siena is a private, non-profit foundation with a registered office and operations to develop applied research and innovation in the field of biotechnology and life sciences.
Micron Biomedical
Grant in 2025
Micron Biomedical is a clinical-stage biopharmaceutical company founded in 2014 and based in Atlanta, Georgia. The company focuses on developing innovative microneedle patches designed for administering vaccines, specifically targeting influenza and polio. Its proprietary microneedle technology aims to enhance the protective and therapeutic effects of vaccines while improving patient compliance and simplifying the administration process. Through its advanced delivery methods, Micron Biomedical seeks to facilitate the development of vaccines that can address critical healthcare needs.
Accumulus Synergy
Grant in 2024
We are developing a global information exchange platform to accelerate the availability of safe and effective medicines.
Valneva is a biopharmaceutical company specializing in the development, manufacturing, and distribution of prophylactic vaccines for infectious diseases. Its portfolio comprises two commercially available vaccines (IXIARO/JESPECT for Japanese encephalitis and DUKORAL for traveler's diarrhea), along with vaccine candidates targeting Lyme disease, chikungunya virus, and COVID-19. Valneva operates through segments including Commercialized Vaccines, Covid-19 Vaccine, Vaccine Candidates, and Technologies & Services. The company aims to address significant unmet medical needs in infectious diseases by leveraging its expertise and capabilities to advance vaccine candidates through clinical trials and ultimately commercialize them.
Apriori Bio is a health security company dedicated to safeguarding humanity from viral threats. Utilizing an innovative technology platform, the company designs variant-resilient vaccines and develops antibody drugs aimed at addressing both existing and potential viral variants. By providing real-time insights into the landscape of these threats, Apriori Bio enhances preparedness for future outbreaks. Through its focused approach, the company seeks to deliver durable protection against rapidly evolving viruses, contributing to global health security.
BioNTech is a Germany-based biotechnology company that specializes in developing innovative immunotherapies for cancer and other serious diseases, as well as vaccines for infectious diseases, including COVID-19. The company’s oncology pipeline includes a range of drug classes, such as mRNA-based drugs that encode antigens and neoantigens, cell therapies, bispecific antibodies, and antibody-drug conjugates. BioNTech has established partnerships with several major pharmaceutical companies, enhancing its research and development capabilities. Its COVID-19 vaccine, Comirnaty, represents its first commercialized product, demonstrating the company's commitment to addressing urgent health challenges through advanced therapeutic approaches.
aVaxziPen
Funding Round in 2023
aVaxziPen is a clinical-stage pharmaceutical company dedicated to developing next-generation vaccines and therapeutics for infectious diseases and emerging pathogens. The company specializes in innovative drug-device combination products, utilizing its proprietary ImplaVax solid dose formulation and device technology. This approach focuses on creating novel solid dose vaccines aimed at a variety of infectious diseases, enhancing both the performance and delivery of these medical solutions. aVaxziPen is committed to advancing its vaccine and therapeutic development services to facilitate the transition of products into human clinical trials.
Aspen Pharmacare Holdings
Grant in 2022
Aspen Pharmacare Holdings Limited is a global specialty pharmaceutical company headquartered in Durban, South Africa. It manufactures and supplies a diverse portfolio of specialty, branded, and generic pharmaceutical products across more than 150 countries. The company operates through two main segments: Commercial Pharmaceuticals and Manufacturing. Aspen offers a range of products, including general anaesthetics, muscle relaxants, cytotoxic medicines, and injectable anticoagulants, with a focus on low molecular weight heparins. Additionally, Aspen engages in the contract manufacturing and supply of active pharmaceutical ingredients and finished dose pharmaceuticals for third parties. The company's extensive product offerings include oral solids, injectables, liquids, semi-solids, and biologicals. With a strong presence in various international markets, including Africa, Asia, Europe, and the Americas, Aspen continues to expand its operations through strategic acquisitions and partnerships. Founded in 1850, Aspen has established itself as a leading player in the pharmaceutical industry.
SK Bioscience
Grant in 2022
SK Bioscience is a South Korean pharmaceutical company focused on the development and manufacturing of vaccines. The company is notable for introducing SKYCellflu, the first cell culture influenza vaccine in Korea, and has since expanded its portfolio to include the SKYCellflu Quadrivalent prefilled syringe and a 13-valent Pneumococcal Conjugate Vaccine. In addition to these licensed products, SK Bioscience is actively engaged in the development of several other vaccines, including a recombinant rotavirus vaccine, a new typhoid conjugate vaccine, and an innovative pneumococcal vaccine, often in collaboration with external partners. The company is dedicated to building a robust infrastructure for continuous vaccine development, positioning itself as a key player in the global vaccine landscape.
Codiak Biosciences
Post in 2022
Codiak BioSciences is a clinical-stage biopharmaceutical company dedicated to developing exosome-based therapeutics, a novel class of medicines with the potential to address various diseases with significant unmet medical needs. The company employs its proprietary engEx Platform, which allows for the engineering and manufacturing of exosomes, leveraging their natural role as intercellular messengers. Codiak's pipeline includes product candidates such as exoSTING and exoIL-12, targeting diverse therapeutic areas including oncology, neuro-oncology, neurology, neuromuscular diseases, and infectious diseases. Additionally, the company collaborates with the Ragon Institute to explore the potential of its exoVACC platform for vaccines against SARS-CoV-2 and HIV. Founded in 2015 and headquartered in Cambridge, Massachusetts, Codiak aims to transform therapeutic approaches by harnessing the unique properties of exosomes.
Sabin Vaccine Institute
Grant in 2022
Sabin Vaccine Institute is dedicated to enhancing vaccine accessibility and promoting immunization, particularly in low- and middle-income populations that are most vulnerable to infectious diseases. The organization focuses on the development of innovative vaccines aimed at preventing a wide range of diseases, thereby improving public health outcomes. By striving to make vaccines available globally, Sabin Vaccine Institute seeks to benefit individuals and communities, ultimately contributing to better healthcare and disease prevention efforts worldwide.
NEC OncoImmunity
Seed Round in 2022
NEC OncoImmunity AS is a bioinformatics company based in Oslo, Norway, specializing in the development of machine-learning software solutions for personalized cancer immunotherapy. Founded in 2014, the company focuses on addressing critical knowledge gaps in identifying immunogenic neoantigens, which are essential for creating targeted cancer vaccines and cell therapies. Its proprietary platform aids in the selection of patients for these therapies and efficiently identifies optimal neoantigen targets within a clinically actionable timeframe. NEC OncoImmunity's software solutions are designed to support healthcare institutions and research organizations in the discovery of neoantigen-based personalized immunotherapies and biomarkers, enhancing the overall effectiveness of cancer treatment strategies. The company operates as a subsidiary of NEC Corporation, having rebranded from OncoImmunity AS in July 2019.
DIOSynVax is a vaccine antigen design company focused on enhancing vaccine development through innovative technology. The company specializes in digitally designing, immune-optimized selecting, and synthesizing vaccines to improve protection against both emerging and re-emerging pathogens, including influenza, COVID-19, and viral hemorrhagic fevers. By leveraging its advanced technology, DIOSynVax aims to expedite the vaccine development process, ultimately enabling healthcare providers to treat patients more effectively and facilitate quicker recovery from various diseases. Through its efforts, DIOSynVax seeks to make significant advancements in public health by addressing the challenges posed by existing and future viruses.
Clover Biopharmaceuticals
Post in 2021
Clover Biopharmaceuticals, established in 2016, is a global, clinical-stage biotech company dedicated to discovering, developing, and commercializing innovative biologics targeting trimerization-dependent pathways in oncology and autoimmune diseases. The company's proprietary Trimer-Tag© technology platform enables the creation of novel biologics. Additionally, Clover employs its in-house cGMP biomanufacturing capabilities for select biosimilars development.
Vaccine and Infectious Disease Organization
Grant in 2021
Vaccine and Infectious Disease Organization (VIDO) at the University of Saskatchewan is a world leader in developing vaccines and technologies against infectious diseases.
MigVax Ltd., based in Kiryat Shmona, Israel, is a subsidiary of MIGAL - Galilee Research Institute LTD. It specializes in the development, manufacture, and commercialization of vaccines for viral infections in humans. The company's primary focus is on creating a vaccine against the infectious bronchitis virus, which shares similarities with human coronaviruses, enabling it to potentially tackle various diseases including coronavirus and bird flu. MigVax operates as an Israeli medical technology startup.
Gritstone bio
Grant in 2021
Gritstone bio is a biotechnology company focused on developing immunotherapies for cancer and infectious diseases. The company initially concentrated on tumor-specific neoantigens but has expanded its programs to include viral antigens found on the surface of infected cells. Gritstone bio's approach leverages the body's natural immune system recognition of targets on abnormal cells, which is applicable to both anti-tumor and anti-viral immunity. Their pipeline includes several product candidates for treating solid tumors, such as GRANITE, SLATE, and CORAL. The company operates in a field that has seen significant advancements with the development and commercialization of immunotherapy drugs like checkpoint inhibitors, transforming cancer treatment.
Dynavax Technologies
Post in 2021
Dynavax Technologies Corporation is a biopharmaceutical company specializing in the development and commercialization of innovative vaccines. Its flagship product, HEPLISAV-B, is a recombinant adjuvanted hepatitis B vaccine approved for use in adults aged 18 years and older, targeting all known subtypes of the hepatitis B virus. The company utilizes its proprietary Toll-like Receptor Immune Modulation Platform to enhance both innate and adaptive immune responses. Dynavax is actively advancing its immuno-oncology portfolio and has several development-stage products, including SD-101 and DV281, aimed at various cancer indications. In addition, the company engages in multiple research collaborations to develop adjuvanted vaccines for infectious diseases, including COVID-19, partnering with organizations such as Clover Biopharmaceuticals, the University of Queensland, and the Coalition for Epidemic Preparedness Innovations. Established in 1996 and headquartered in Emeryville, California, Dynavax continues to expand its role in vaccine development.
Bharat Biotech
Grant in 2020
Bharat Biotech Ltd. is a biotechnology company based in Hyderabad, India, specializing in the research, development, and manufacture of vaccines and biotherapeutics. Established in 1996, the company offers a diverse range of products, including vaccines such as Revac-B+, a recombinant hepatitis-B vaccine; TYPBAR, a typhoid vaccine; BIOPOLIO, a poliomyelitis vaccine; and INDIRAB, a rabies vaccine. Additionally, Bharat Biotech produces various biotherapeutics, like REGEN-D, a recombinant human epidermal growth factor gel for diabetic foot ulcers and burns, as well as treatments for osteoarthritis and other conditions. The company also provides women's healthcare products and has developed a cell culture H1N1 swine flu vaccine. Bharat Biotech exports its products to several countries, including Kenya, Zambia, and the Philippines, with a focus on creating affordable and effective therapies for neglected diseases.
Novavax Inc., established in 1987 and headquartered in Gaithersburg, Maryland, is a late-stage biotechnology company dedicated to discovering, developing, and commercializing vaccines to prevent serious infectious diseases worldwide. Its primary focus lies in advancing vaccine candidates through clinical trials, with notable projects including ResVax for RSV in infants via maternal immunization (Phase III), NanoFlu for seasonal influenza in older adults (Phase III), and NVX-CoV2373 for COVID-19 (preclinical). Novavax's proprietary Matrix-M adjuvant enhances immune response and enables lower antigen doses. The company collaborates globally to address urgent health needs, with Europe being its primary revenue source.
Inovio Pharmaceuticals
Grant in 2020
Inovio Pharmaceuticals, Inc. is a biotechnology company dedicated to the discovery, development, and commercialization of DNA medicines aimed at treating, curing, and protecting individuals from diseases related to human papillomavirus (HPV), cancer, and infectious diseases. The company's innovative SynCon immunotherapy design enables the immune system to target cancerous cells while providing cross-strain protection against various pathogens. Inovio's clinical studies focus on HPV-associated precancers, cancers, and other disorders, as well as diseases such as glioblastoma multiforme, HIV, and COVID-19. The company has developed a proprietary delivery system that allows DNA medicine to be introduced directly into cells, producing a strong immune response. Notably, its lead candidate, VGX-3100, is undergoing Phase 3 trials for precancerous cervical dysplasia, having shown promise in earlier trials by effectively clearing high-risk HPV strains. Founded in 1979 and headquartered in Plymouth Meeting, Pennsylvania, Inovio collaborates with various partners, including major pharmaceutical companies and research institutions, to advance its clinical initiatives and expand its therapeutic reach.
Themis Bioscience
Grant in 2020
Themis Bioscience N.V. is a clinical-stage biopharmaceutical company headquartered in Vienna, Austria, specializing in immunomodulation to develop products aimed at protecting against infectious diseases. Founded in 2009, the company’s lead product candidate, MV-CHIK, has completed Phase II clinical trials for chikungunya treatment. Themis is also engaged in developing vaccines for various health threats, including cancer, Zika virus, Lassa fever, and MERS. Themis leverages its advanced understanding of immune system mechanisms through its innovative vaccine platform, focusing on both emerging and specialized indications. The company has established research collaborations and exclusive licensing agreements to enhance its development capabilities, positioning itself as a strategic partner for leading biotechnology and pharmaceutical firms.
Novavax Inc., established in 1987 and headquartered in Gaithersburg, Maryland, is a late-stage biotechnology company dedicated to discovering, developing, and commercializing vaccines to prevent serious infectious diseases worldwide. Its primary focus lies in advancing vaccine candidates through clinical trials, with notable projects including ResVax for RSV in infants via maternal immunization (Phase III), NanoFlu for seasonal influenza in older adults (Phase III), and NVX-CoV2373 for COVID-19 (preclinical). Novavax's proprietary Matrix-M adjuvant enhances immune response and enables lower antigen doses. The company collaborates globally to address urgent health needs, with Europe being its primary revenue source.
Inovio Pharmaceuticals
Grant in 2020
Inovio Pharmaceuticals, Inc. is a biotechnology company dedicated to the discovery, development, and commercialization of DNA medicines aimed at treating, curing, and protecting individuals from diseases related to human papillomavirus (HPV), cancer, and infectious diseases. The company's innovative SynCon immunotherapy design enables the immune system to target cancerous cells while providing cross-strain protection against various pathogens. Inovio's clinical studies focus on HPV-associated precancers, cancers, and other disorders, as well as diseases such as glioblastoma multiforme, HIV, and COVID-19. The company has developed a proprietary delivery system that allows DNA medicine to be introduced directly into cells, producing a strong immune response. Notably, its lead candidate, VGX-3100, is undergoing Phase 3 trials for precancerous cervical dysplasia, having shown promise in earlier trials by effectively clearing high-risk HPV strains. Founded in 1979 and headquartered in Plymouth Meeting, Pennsylvania, Inovio collaborates with various partners, including major pharmaceutical companies and research institutions, to advance its clinical initiatives and expand its therapeutic reach.
Themis Bioscience
Grant in 2019
Themis Bioscience N.V. is a clinical-stage biopharmaceutical company headquartered in Vienna, Austria, specializing in immunomodulation to develop products aimed at protecting against infectious diseases. Founded in 2009, the company’s lead product candidate, MV-CHIK, has completed Phase II clinical trials for chikungunya treatment. Themis is also engaged in developing vaccines for various health threats, including cancer, Zika virus, Lassa fever, and MERS. Themis leverages its advanced understanding of immune system mechanisms through its innovative vaccine platform, focusing on both emerging and specialized indications. The company has established research collaborations and exclusive licensing agreements to enhance its development capabilities, positioning itself as a strategic partner for leading biotechnology and pharmaceutical firms.
Themis Bioscience
Grant in 2018
Themis Bioscience N.V. is a clinical-stage biopharmaceutical company headquartered in Vienna, Austria, specializing in immunomodulation to develop products aimed at protecting against infectious diseases. Founded in 2009, the company’s lead product candidate, MV-CHIK, has completed Phase II clinical trials for chikungunya treatment. Themis is also engaged in developing vaccines for various health threats, including cancer, Zika virus, Lassa fever, and MERS. Themis leverages its advanced understanding of immune system mechanisms through its innovative vaccine platform, focusing on both emerging and specialized indications. The company has established research collaborations and exclusive licensing agreements to enhance its development capabilities, positioning itself as a strategic partner for leading biotechnology and pharmaceutical firms.