DCVC

DCVC, founded in 2010 and based in Palo Alto, California, is a venture capital firm that invests in seed and early-stage companies across various sectors, including artificial intelligence, exascale computing, climate, engineering, materials science, robotics, space, water, biology, defense, security, and deep tech. The firm leverages a unique team of experienced venture capitalists, technology entrepreneurs, and practicing engineers, bringing together over 35 technology executives and experts from prestigious institutions. DCVC also operates a dedicated fund, DCVC Bio, which focuses on early-stage startups in computational biology, aiming to harness advancements in genetic sequencing, artificial intelligence, and automation to drive innovation in synthetic biology, medicine, and agriculture. With a proven track record of over 150 companies and 40 material exits, DCVC is committed to fostering deep technological changes that enhance life sciences and IT infrastructure.

Alan Cohen

General Partner

Anna Fokina

Investment Director DCVC Bio

James Hardiman

General Partner

Patrick Mccauley

Operating Partner

Matt Ocko

Co-Founder & Managing Partner

Jason Pontin

General Partner & Member of Investment Team

Kristen Rocca

Principal

Matt Trevithick

Partner

Milo Werner

General Partner

435 past transactions

Auradine

Series A in 2023
Auradinescalability, sustainability and security solutions for the infrastructure, enabled by revolutionary blockchain, security, zero-knowledge and AI technologies.
Ascend supports manufacturing and process development projects from design through to clinical and commercial scales. They partner with biotechnology teams to embed scalable manufacturing in their operations from the beginning. They respond to customer inquiries by phone and contact form.

Halter

Series C in 2023
Halter creates GPS enabled, solar powered collars for cows. The collar hardware allows farmers to use simple tablet app software to remotely set geographic boundaries for cattle, virtual fences. Farmers use Halter's system to avoid physically herding cows, maximizing farmer time and productivity.

Amogy

Series B in 2023
Amogy is a start-up, located in Brooklyn, New York and is working on a novel carbon-free energy storage system using ammonia as a fuel.

evonetix

Series B in 2023
Evonetix Ltd is a biotechnology company based in Little Chesterford, United Kingdom, founded in 2015. The company focuses on developing innovative technology for the parallel synthesis of DNA on silicon arrays, which supports advancements in synthetic biology. Situated within the prestigious Cambridge cluster of high-tech and life science organizations, Evonetix aims to revolutionize DNA synthesis through novel techniques that enhance efficiency and capability. The team at Evonetix comprises experienced professionals from various scientific and engineering disciplines, bringing together a wealth of knowledge to drive the commercialization of their technology.

Auron Therapeutics

Series A in 2022
Auron Therapeutics is to develop therapies to cure cancer by radically changing the paradigm of cancer therapeutics from cell killing, to transformation of malignant cells into normal cells. This transformation, called differentiation therapy, reactivates endogenous cellular programs to elicit tumor cell maturation and the transition from cancer to normal tissue. Its unique platforms allow for integration of large-omic datasets and miniaturized high throughput flow cytometry to rapidly identify and validate multiple targets and drugs in primary human patient samples.

Twelve

Series B in 2022
Opus 12 captures carbon emissions where pollution is generated and turns the CO2 into chemicals like methane, ethylene, and ethanol. Their technology bolts onto any source of CO₂ emissions, and with only water and electricity as inputs, transforms that CO₂ into some of the world's most critical chemical products. The company plans to recycle CO2 emissions into liquid fuels and chemical precursors cost-competitively with petroleum-sourced products. It also develops a profitable solution to carbon emissions by recycling CO₂ into cost-competitive chemicals and fuels. It is based in Berkeley, California.

Relation Therapeutics

Seed Round in 2022
Relation Therapeutics engages in humanizing drug discovery and development. It leverages human genetics and clinical omics data and utilizes patient-derived tissue samples with functional genomics interventional experiments to identify, validate and prosecute therapeutic programs.

Zap Energy

Series C in 2022
Zap Energy Inc. designs and manufactures sheared-flow stabilized Z-Pinch fusion reactors aimed at providing a low-carbon and cost-effective energy source. The company's innovative approach stabilizes plasma using sheared flows instead of traditional magnetic fields, utilizing electric currents to create a magnetic field that confines and compresses the plasma. This method allows for increased pressure and density within the plasma, enhancing the efficiency of the fusion process. Founded in 2017 and headquartered in Seattle, Washington, Zap Energy's reactors are noted for being compact, scalable, and offering a promising pathway toward commercially viable fusion energy solutions.

Sickbay

Venture Round in 2022
Sickbay, developed by Medical Informatics Corp., is a software platform designed to enhance patient monitoring and analytics in healthcare settings. It archives, aggregates, and transforms high-resolution waveform data from various medical devices, enabling real-time access and analysis of patient information. The platform supports continuous data collection and employs machine learning and artificial intelligence to deliver predictive analytics that facilitate data-driven medicine and patient-centered care. Sickbay also addresses alarm management by reducing alarm noise and ensuring that relevant alerts reach care providers. This comprehensive approach assists doctors, nurses, hospital administrators, and medical researchers in making informed decisions to improve patient outcomes. Founded in 2010 and headquartered in Houston, Texas, Medical Informatics Corp. aims to provide innovative solutions that enhance the efficiency and effectiveness of healthcare delivery.

Zeno Power

Series A in 2022
They are developing a next-generation radioisotope power system that converts the heat from recycled nuclear waste into electricity.Their novel fuel and shielding design results in a system that is lightweight, cost-effective, and provides always-on, resilient power for years at a time.

Capella Space

Series C in 2022
Capella Space is an information services company that provides sub 0.5m very high-resolution synthetic aperture radar earth observation imagery. Through a constellation of small satellites, Capella is providing easy access to frequent, timely, and flexible information affecting dozens of industries worldwide. Capella’s high-resolution SAR satellites are matched with unparalleled infrastructure to deliver reliable global insights that sharpen the understanding of the changing world, improving decisions about commerce, conservation, and well-being on Earth. The company aims to make timely Earth observation an essential tool for commerce, conservation, and well-being. Capella Space was founded in 2014 and based in San Francisco, California.

Agility Robotics

Series B in 2022
Agility Robotics Inc. is a robotics development company founded in 2015 and based in Albany, Oregon. It specializes in designing and developing bipedal robots, notably Cassie, which is capable of walking and running. The company leverages its expertise in legged locomotion, rooted in extensive academic research, to create robots that serve as mobile sensor platforms and can operate in real-world environments. Agility Robotics aims to produce efficient, agile, and robust mobility solutions that can work alongside humans in various settings, such as offices, factories, and homes. Its technology enables clients to automate tasks in diverse terrains with minimal programming, addressing the practical needs of academic, corporate, and military sectors.

Unlearn

Series B in 2022
Unlearn is a San Francisco-based company founded in 2017 that specializes in using artificial intelligence to enhance clinical research. It develops innovative software tools aimed at improving clinical trial design, including the creation of Digital Twins to generate Intelligent Control Arms. By utilizing historical datasets and disease-specific machine-learning models, Unlearn produces virtual placebo patients derived from actual patient baseline data, which helps to increase trial power, accelerate timelines, and provide patient-level insights. This approach reduces or eliminates the need for concurrent control arms in clinical studies, streamlining the research process. Unlearn has garnered significant attention, securing $20 million in funding and collaborating with leading pharmaceutical companies. Its work has been recognized in prestigious publications, including a peer-reviewed article in Nature, and it has been acknowledged as a key player in digital health innovation. The company continues to engage with regulators and industry leaders to drive advancements in clinical research through the application of AI technologies.

Aclarity

Seed Round in 2022
Aclarity, LLC Manufactures and markets water purification devices for homes. Its water purification devices remove pathogens, metals, and other impurities from water. Aclarity, LLC was founded in 2017 and is headquartered in the United States.

zkLend

Seed Round in 2022
zkLend is a Layer 2 money-market protocol developed on StarkNet, designed to enhance financial transactions through the use of zk-rollup technology. This decentralized platform leverages Ethereum's security while offering superior transaction speed and cost efficiency. By combining these advantages, zkLend enables users to conduct transactions securely and privately, making it an attractive option for those seeking to engage in decentralized finance.

Brimstone Energy

Series A in 2022
Brimstone Energy is a hardware cleantech startup that aims to reduce CO2 emissions through innovative technologies.

Plotlogic

Series A in 2022
Plotlogic Pty Ltd is a Brisbane-based company that specializes in developing advanced ore characterization systems for the mining industry. The firm employs hyperspectral imaging technology through its flagship product, OreSense LV, which identifies variations in a mine's geological model. Additionally, it offers OreBlocks, an API designed to enhance planning processes, and OreCheck, which provides real-time alerts regarding material variations. The technology aims to improve ore recovery and minimize dilution while also reducing carbon emissions and operational costs. Plotlogic's systems are applicable to various commodities, including coal, iron ore, and gold. Founded in 2005, the company is dedicated to offering customized support services alongside its innovative solutions.

Creyon

Series A in 2022
Creyon Bio is a pre-clinical stage company focused on revolutionizing drug development through a data-driven approach. The company specializes in creating proprietary datasets that enhance the design and engineering of RNA-based medicines, particularly precision oligonucleotide-based therapies. By leveraging advanced machine learning models, Creyon Bio aims to identify essential design rules and engineering principles that facilitate the development of safe and effective oligonucleotide-based medicines. This innovative methodology is intended to streamline the drug development process, ultimately helping the healthcare sector reduce costs associated with bringing new therapies to market.

Amogy

Series A in 2021
Amogy is a start-up, located in Brooklyn, New York and is working on a novel carbon-free energy storage system using ammonia as a fuel.

Petra

Series A in 2021
Petra is a Robotics company that focuses solely on underground utilities. Petra enables undergrounding critical utilities by boring utility tunnels through previously impenetrable geologies.

Q-CTRL

Series B in 2021
Q-CTRL Pty Ltd, established in 2017 and located in Pyrmont, Australia, specializes in developing software tools and firmware for the quantum computing sector. The company focuses on addressing critical challenges in quantum technology, such as noise and decoherence, which affect the performance of quantum devices. By leveraging its expertise in quantum control engineering, Q-CTRL provides intuitive software solutions designed to reduce errors in quantum bits, thereby stabilizing quantum hardware. Its offerings are particularly relevant in the NISQ (Noisy Intermediate-Scale Quantum) era, allowing users to better understand and manage the impacts of noise and errors in quantum systems. Through its innovative approach, Q-CTRL aims to make quantum technology more practical and accessible for various applications, including quantum sensing in defense.

Gradle Inc.

Series C in 2021
Gradle, Inc. consists of the Gradle Build Tool (www.gradle.org) and Gradle Enterprise (www.gradle.com). Gradle Build Tool is the most popular build tool for open source JVM projects on GitHub. It is downloaded on average more than 19 million times per month and has been counted in the Top 20 Most Popular Open Source Projects for IT by Techcrunch. Many popular open source projects are using Gradle, with Spring Boot, JUnit, and JetBrains (Kotlin) being a prominent examples. Gradle Enterprise is the first only software build performance acceleration and analytics platform. The most prestigious software development and build/test engineering teams in the world use Gradle Enterprise to cut build times in half and give developers back one day per week in lost productivity time. Gradle Enterprise is a self-hosted solution that leverages acceleration technologies to speed up the software build and test process and data analytics to make troubleshooting more efficient. It is a key enabling technology for the emerging discipline of Developer Productivity Engineering in both Gradle and Maven build environments.

nTopology

Series D in 2021
nTopology, Inc. develops engineering design software that enhances manufacturing processes. Its primary offering, nTopology, allows engineers to create lightweight and optimized parts tailored to functional requirements. The software integrates design, simulation, and advanced manufacturing into a cohesive workflow, addressing geometry bottlenecks and enhancing team collaboration. Key features include Lightweighting, Architected Materials, Topology Optimization, Additive Manufacturing, and Design Analysis. nTopology's tools enable precise control over spatial variations, facilitating a broader range of designs and effective utilization of analysis data. The company serves various industries, including aerospace and defense, medical, automotive, consumer products, and education. Founded in 2013 and based in New York, nTopology aims to redefine engineering design tools for advanced manufacturing.

Kettle

Series A in 2021
Kettle Inc. is an innovative company based in Kensington, California, specializing in online risk analysis for the insurance industry. Founded in 2020, Kettle develops a machine-learning powered platform that utilizes deep learning algorithms to analyze over seven billion lines of satellite, weather, and ground truth data. By employing Swarm Neural Networks, the platform identifies patterns that enhance the accuracy of risk predictions related to climate change, thereby assisting insurers in managing catastrophic risks. Kettle's approach aims to improve underwriting processes and reduce loss ratios, enabling the sale of reinsurance to other insurers while effectively balancing risk in an evolving climate landscape.

StarkWare

Series C in 2021
StarkWare Industries Ltd, founded in 2017 and based in Netanya, Israel, specializes in developing software and hardware for generating and verifying computational integrity proofs. The company has created STARK, a zero-knowledge proof protocol that enhances scalability and privacy in blockchain applications. This technology allows for increased transaction throughput and enables off-chain computation while ensuring that sensitive underlying data remains confidential. StarkWare's solutions are designed to improve the efficiency, security, and overall user experience of blockchain systems, making them a key player in the field of cryptographic proof platforms.

Jupiter Intelligence

Series C in 2021
Jupiter Intelligence, Inc. specializes in developing tools and platforms that provide comprehensive weather and climate data, trend visualizations, forecasts, and risk assessments. The company offers the ClimateScore Intelligence Platform, which utilizes cloud computing to integrate multiple prediction models based on data from millions of ground-based and satellite sensors. Additionally, Jupiter provides FloodScore and HeatScore services, which help users prepare for flooding and mitigate temperature-related impacts from climate change, respectively. These services focus on climate risk assessment and management in urban regions such as New York City, South Florida, and the Atlantic Coast, with plans for global expansion. Jupiter's models are informed by the latest scientific research from the global Earth and Ocean Systems community. Founded in 2017 and based in San Mateo, California, Jupiter Intelligence was previously known as Jupiter Technology Systems, Inc. before rebranding in December 2017.

TrustPoint

Seed Round in 2021
TrustPoint is developing a next-generation GPS signal processing technology to provide the performance and reliability required for safety-critical automation, vital infrastructure, and seamless augmented reality.

Kentik

Series C in 2021
Kentik Technologies, Inc. is a network intelligence platform that delivers cloud-based real-time visibility and analytics solutions for network and security operators. Founded in 2014 and headquartered in San Francisco, California, the company offers Kentik Detect, a big data-based software-as-a-service that transforms network data into actionable intelligence. This platform enables clients to conduct ad-hoc analytics for improved operations, capacity optimization, anomaly resolution, and DDoS detection, thereby enhancing application and service protection. Kentik also provides My Kentik, a self-service network analytics tool, and an AIOps platform aimed at streamlining network operations. Additionally, the company serves various industries, including financial services, media and entertainment, cloud infrastructure, and telecommunications, offering tailored solutions for visibility, performance, detection, planning, and integration. Kentik was previously known as CloudHelix, Inc. before rebranding in September 2014.

CH4 Global

Series A in 2021
CH4 Global Inc. is a holding company based in San Francisco, California, that specializes in producing seaweed bio-products aimed at reducing methane emissions from livestock. Founded in 2019, the company focuses on Asparagopsis armata, a seaweed supplement that has been scientifically proven to decrease methane emissions from ruminant animals such as cows, goats, sheep, and deer by up to 90%. By leveraging advanced aquaculture techniques, CH4 Global provides innovative solutions to mitigate greenhouse gases on a global scale, with its products offered through subsidiaries in the United States, Australia, New Zealand, and the Pacific. The company has attracted investment from family offices and private investors, as well as support from government organizations, to further its mission of addressing climate change while providing benefits like carbon credits for farmers and food producers.

CodeSee

Seed Round in 2021
CodeSee analyzes the data flowing through your system to maintain an updated map of your system architecture, its components, and the connections between them. Developers can explore at a high level, or dive in and see the data right next to the code. In other words...We make grokking a codebase easy. Developers stop feeling like outsiders and start feeling like high performers. Faster.

GenEdit

Series A in 2021
GenEdit, Inc. focuses on the development of novel, non-viral, nanoparticle-based delivery technology and enabling next generation CRISPR-based gene therapies. The foundation of our CRISPR-Nanoparticle Technology Platform is based on successfully engineering the individual components of the CRISPR system to overcome the limitations of existing delivery vehicles for CRISPR-based therapeutics.

Insight M

Series C in 2021
Kairos Aerospace provides large-scale, aerial monitoring of methane emissions. The company completed the first-ever basin-wide aerial survey for methane detection in its 2019 survey of the Permian Basin. Kairos Aerospace’s mission is to improve operational excellence for the oil and gas industry with cost-effective, efficient methane reductions at scale.

EARTH AI

Seed Round in 2021
Earth AI Pty Ltd. develops artificial intelligence (AI) based software that locates areas of mineralization in greenfield and remote areas with no pre-existing geological data. The company gives geologists location suggestions for mineral exposure and auto generates precise geological maps from satellite, geophysical, and geochemical datasets. Earth AI Pty Ltd. was founded in 2016 and is based in Parramatta, Australia.

Frontier Medicines

Series B in 2021
Frontier Medicines Corporation is a pre-clinical stage biopharmaceutical company based in South San Francisco, California, founded in 2018. The company specializes in discovering and developing medicines that target cancer-causing proteins through its innovative chemoproteomics platform. This platform utilizes advanced computational techniques and machine learning to identify new binding pockets on proteins, thereby facilitating the discovery and development of small-molecule drugs. By enhancing the drug development process, Frontier Medicines aims to deliver breakthrough therapies that can significantly change the treatment landscape for debilitating diseases.

Pivot Bio

Series D in 2021
Pivot Bio is a biotechnology company founded in 2010 and based in Emeryville, California. The company specializes in advancing crop nutrition through a deep understanding of the microbiome. By leveraging engineering principles and data science, Pivot Bio develops innovative solutions that utilize naturally occurring microbes to enhance crop yield and quality. Their proprietary ON Technology aims to provide essential nutrients to crops, specifically focusing on enabling microbes to fix and supply nitrogen for corn. This approach seeks to offer a sustainable alternative to traditional chemical fertilizers and pesticides, helping farmers improve their yields while addressing the nutritional needs of the growing global population. Through collaboration and communication, Pivot Bio is dedicated to transforming agricultural practices and contributing to a healthier planet.

Stemson Therapeutics

Series A in 2021
Stemson Therapeutics, LLC operates as a cell therapy company that helps to restore natural hair. The company produces cells required to regenerate hair follicles using the novel cell engineering process. Its products include the stemson solution, a solution that generates novo follicles using induced pluripotent stem cells (iPSC) to grow new Dermal Papilla. The company was founded in 2018 and is based in LA Jolla, California.

Swift Medical

Series B in 2021
Swift Medical Inc. is a Toronto-based company that specializes in wound care management through its mobile application, Swift. This application enables healthcare professionals to measure and document the progression of patients' wounds efficiently. By facilitating real-time sharing of wound images, Swift enhances communication among medical teams and ensures precise and consistent documentation. The platform is designed to provide comprehensive wound care solutions for healthcare enterprises, streamlining the process from initial assessment to ongoing treatment.

Twelve

Series A in 2021
Opus 12 captures carbon emissions where pollution is generated and turns the CO2 into chemicals like methane, ethylene, and ethanol. Their technology bolts onto any source of CO₂ emissions, and with only water and electricity as inputs, transforms that CO₂ into some of the world's most critical chemical products. The company plans to recycle CO2 emissions into liquid fuels and chemical precursors cost-competitively with petroleum-sourced products. It also develops a profitable solution to carbon emissions by recycling CO₂ into cost-competitive chemicals and fuels. It is based in Berkeley, California.

Primer

Series C in 2021
Primer Technologies, Inc. specializes in developing advanced software that employs machine learning and natural language processing to analyze extensive datasets. The company's platform is designed to read and interpret documents in multiple languages, uncover insights, and generate automated reports that rival human analysis. By facilitating the understanding of vast amounts of text data, Primer assists governments and corporations in monitoring and making sense of global information. Founded in 2015 and headquartered in San Francisco, California, Primer aims to bridge the intelligence gap for businesses and enhance their ability to respond to emerging trends in the world.

Strateos

Series B in 2021
Strateos automates chemistry, biology, and tissue analysis into closed loop robotic labs that accelerate drug discovery programs. Through a combination of best-in-class robotics and control systems, advanced software for imaging and analytics, and remote cloud laboratories, we enable our pharmaceutical partners to more rapidly and efficiently discover new drug candidates. Born of a merger between Transcriptic and 3Scan, Strateos combines the strengths of those companies to amplify their impact and accelerate drug discovery. Transcriptic developed the first robotic cloud laboratory platform for on-demand life science research, which is currently in use at several top pharmaceutical and biotechnology companies. 3Scan combined automation, machine learning and computer vision to extract spatial data from tissue samples and create detailed 3D representations as well as quantitative analysis of complex anatomical structures. Now these two portfolios will be combined to offer a suite of technologies for accelerating drug discovery and early development. By expressing life science methods as data, infrastructure virtualization will become possible. "Science-as-a-Service" will power the next generation of discovery, driven by huge efficiencies of both time and money. Transcriptic was founded in 2012 to create a better way to get lab work done. Tired of spending endless hours at the bench pretending to be slow, error-prone robots, they set out to build a modern solution to the day-to-day process of wet lab biology. Drawing on deep computer science and electrical engineering backgrounds in addition to life science, Strateos was born: a meticulously optimized, technology-enabled remote lab. Using state-of-the-art automation and control technology, and an emphasis on user experience and usability, they are working on building a stark contrast to the long, complicated sales process, high prices, and slow turnarounds of traditional CROs. They are working hard to build a great company that can be a true partner for your lab for a long time, progressively enabling ever greater levels of productivity and efficiency. They are scientists building for scientists.

Halter

Series B in 2021
Halter creates GPS enabled, solar powered collars for cows. The collar hardware allows farmers to use simple tablet app software to remotely set geographic boundaries for cattle, virtual fences. Farmers use Halter's system to avoid physically herding cows, maximizing farmer time and productivity.

StarkWare

Series B in 2021
StarkWare Industries Ltd, founded in 2017 and based in Netanya, Israel, specializes in developing software and hardware for generating and verifying computational integrity proofs. The company has created STARK, a zero-knowledge proof protocol that enhances scalability and privacy in blockchain applications. This technology allows for increased transaction throughput and enables off-chain computation while ensuring that sensitive underlying data remains confidential. StarkWare's solutions are designed to improve the efficiency, security, and overall user experience of blockchain systems, making them a key player in the field of cryptographic proof platforms.

Amogy

Funding Round in 2021
Amogy is a start-up, located in Brooklyn, New York and is working on a novel carbon-free energy storage system using ammonia as a fuel.

BioPhero

Series A in 2021
BioPhero ApS provides bio-based pheromones for pest management. The company was founded in 2016 and is based in Kongens Lyngby, Denmark.

Plexium

Series A in 2021
Plexium, Inc. is a biotechnology company based in San Diego, California, established in 2017. The company specializes in drug development, focusing on the identification of small molecules that modulate E3 ligases for therapeutic applications in cancer and neurodegenerative diseases. Plexium employs a DNA-encoded library platform to conduct high-throughput screening, utilizing cell-based assays to discover molecular glues that can alter E3 ligase substrate recognition, thereby inducing, inhibiting, or modulating protein degradation. This innovative approach allows Plexium to selectively target various cancers, including small cell lung and breast tumors, while also exploring mechanisms to enhance immune responses through E3 ligase modulation.

Gro Intelligence

Series B in 2021
Gro Intelligence is a data analytics platform focused on the global agriculture industry, utilizing artificial intelligence and machine learning to analyze a wide range of agricultural data. Founded in 2014 and headquartered in New York, with an additional office in Nairobi, the company aggregates and processes both structured and unstructured data from diverse sources, including satellite imagery and trade reports. By employing proprietary algorithms, Gro Intelligence generates predictive models that provide insights into weather patterns, trade flows, pricing dynamics, and production metrics. This enables financial institutions, corporations, and public sector entities to make informed decisions based on comprehensive and timely information. The company has attracted significant investment, raising $20 million to date from notable investors. With approximately 50 employees, Gro Intelligence aims to bridge data gaps within the agricultural sector, enhancing productivity and access to capital for stakeholders across the ecosystem.

Deepcell

Series A in 2020
Deepcell, Inc. is a company based in Mountain View, California, focused on advancing diagnostic technologies through a non-invasive approach. Founded in 2015, it has developed a microfluidic imaging platform that leverages artificial intelligence to classify cells by their visual features. This technology allows for the isolation of viable cells based on their morphological characteristics, facilitating detailed genetic health assessments from standard blood samples. By enabling insights at the single-cell level, Deepcell aims to improve the diagnosis and treatment of various diseases, offering researchers a valuable alternative to invasive diagnostic methods.

Subtle Medical

Series A in 2020
Subtle Medical, Inc., a healthcare technology company, develops medical imaging software for clinical imaging centers and hospitals. Its product includes SubtleMR, an artificial intelligence-based image processing software that reduces image noise and increases image sharpness for non-contrast enhanced magnetic resonance imaging (MRI). It enables to reduce cost, imaging time, and radiation/contrast dose. The company was founded in 2017 and is based in Menlo Park, California.

Carbon Health

Series C in 2020
Carbon Health is a tech-enabled healthcare company founded in 2015 and headquartered in San Francisco, California. It provides a mobile application that facilitates primary care services, allowing users to manage their treatment plans, prescriptions, and lab reports in one place. The company offers omnichannel care through various access points, including clinics, pop-up sites, video consultations, and its application, ensuring convenient and accessible healthcare for patients. Additionally, Carbon Health developed a coronavirus assessment tool and has established COVID-19 testing sites in California, further enhancing its commitment to delivering comprehensive healthcare services.

Agility Robotics

Series B in 2020
Agility Robotics Inc. is a robotics development company founded in 2015 and based in Albany, Oregon. It specializes in designing and developing bipedal robots, notably Cassie, which is capable of walking and running. The company leverages its expertise in legged locomotion, rooted in extensive academic research, to create robots that serve as mobile sensor platforms and can operate in real-world environments. Agility Robotics aims to produce efficient, agile, and robust mobility solutions that can work alongside humans in various settings, such as offices, factories, and homes. Its technology enables clients to automate tasks in diverse terrains with minimal programming, addressing the practical needs of academic, corporate, and military sectors.

Alchemab Therapeutics

Series A in 2020
Alchemab Therapeutics is developing natural protective antibodies designed to keep people free of hard-to-treat diseases. They are building their transformative engine to identify novel drug targets and develop a broad pipeline of novel antibody therapeutics for hard-to-treat cancers, neurodegenerative conditions, and infectious diseases.

Golden

Series A in 2020
Golden is a developer of a self-constructing knowledge database used to accelerate discovery and education. The company uses and leverages human effort by using machine intelligence to make the process of gathering and communicating knowledge simpler. It combines a powerful search across several entities with fine-grain alerts to stay on top of changes, and semi-automatic research assistance for gaps in knowledge that enable people in organizations to stay current, understand and leverage the latest trends in their industry.

Curative

Seed Round in 2020
Curative provide communities with 24-hour COVID-19 testing at scale with a significantly more efficient and precise oral fluid test that reduces pressure on medical supply chains and healthcare workers.

nTopology

Series C in 2020
nTopology, Inc. develops engineering design software that enhances manufacturing processes. Its primary offering, nTopology, allows engineers to create lightweight and optimized parts tailored to functional requirements. The software integrates design, simulation, and advanced manufacturing into a cohesive workflow, addressing geometry bottlenecks and enhancing team collaboration. Key features include Lightweighting, Architected Materials, Topology Optimization, Additive Manufacturing, and Design Analysis. nTopology's tools enable precise control over spatial variations, facilitating a broader range of designs and effective utilization of analysis data. The company serves various industries, including aerospace and defense, medical, automotive, consumer products, and education. Founded in 2013 and based in New York, nTopology aims to redefine engineering design tools for advanced manufacturing.

Zymergen

Series D in 2020
Zymergen, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. The company focuses on researching, developing, and manufacturing microbes for various industries, including agriculture, chemicals, materials, pharmaceuticals, electronics, and personal care. Zymergen employs a platform that combines automation, machine learning, and genomics to optimize microbial strains, enhancing production processes and fostering improved economic outcomes. The company also offers new product development services, enabling the engineering of novel molecules from diverse microbial sources. With additional offices in Boise, Idaho; Medford, Massachusetts; Seattle, Washington; and Tokyo, Japan, Zymergen integrates advanced technologies to partner with nature in creating innovative materials and products across multiple sectors.

Auransa

Series A in 2020
Auransa is an AI-driven platform for discovering drugs of novel pharmacology from vast amounts of genomics data collected from human disease tissues. The company's platform is used to study molecular disease subtypes and predict compounds and targets for responder patient population. Current internal drug pipeline includes cancer and other diseases. The company has partnership with companies and institutions in biopharma industry.

Atomwise

Series B in 2020
Atomwise Inc. is a deep learning AI technology for structure-based small molecule drug discovery. Atomwise performs hundreds of projects per year in partnership with some of the world’s largest pharmaceutical and agrochemical companies, as well as more than 200 universities and hospitals in 40 countries. Its speed and accuracy make it the most advanced technology for small molecule binding affinity prediction. AtomNet, its AI platform built for drug discovery contains more than 16 billion molecules for virtual screening.

Rigetti Computing

Series C in 2020
Rigetti & Co, Inc., an integrated systems company, designs and manufactures quantum computers and the superconducting quantum processors that power them. It offers Quantum, a cloud services platform that enables its machines to be integrated into any public, private, and hybrid cloud environments. The company also provides Forest, a cloud platform to support programs that use a quantum processor and enables programmers to write quantum applications. Rigetti & Co, Inc. was incorporated in 2013 and is based in Berkeley, California with an additional office in Fremont, California.

Caption Health

Series B in 2020
Caption Health will use this funding to scale up its commercial operations, continue to develop its AI technology platform and form new partnerships. As more providers adopt the Caption AI platform, the company plans to add new clinical capabilities to expand the use of Caption AI in additional care settings.

Horizon Quantum Computing

Seed Round in 2020
Horizon Quantum Computing Pte. Ltd., established in 2018 and headquartered in Singapore, focuses on creating software development tools that facilitate the development of quantum software applications. The company's innovative tools aim to bridge the gap between quantum computing and conventional software development, allowing researchers to enhance their productivity. By utilizing abstraction techniques, Horizon's solutions enable software engineers to engage in quantum application development without requiring prior experience in quantum computing. This approach not only simplifies the development process but also broadens access to quantum-enhanced applications, contributing to advancements in the field of quantum technology.

Proprio, Inc.

Series A in 2020
Proprio, Inc. develops a healthcare system for real-time immersive video and mediated reality interaction. It offers surgical microscopes, navigation systems, loupes, and screens to replace surgical microscopes. The company’s networked camera arrays, depth-sensing technology, and computer graphics processing enables users to navigate live 3D environments with a sense of presence and depth of field from any perspective. Proprio, Inc. was formerly known as eLoupes, Inc. The company was founded in 2016 and is headquartered in Seattle, Washington.

Orca Bio

Series D in 2020
Orca Bio is a clinical-stage cell therapy company dedicated to delivering curative medicine to these patients. Orca Bio has developed a pipeline of proprietary technologies that have the potential to impact over 100 malignant and auto-immune diseases. Orca has assembled a team of world-leading experts and technologists to execute this vision.

Kentik

Venture Round in 2020
Kentik Technologies, Inc. is a network intelligence platform that delivers cloud-based real-time visibility and analytics solutions for network and security operators. Founded in 2014 and headquartered in San Francisco, California, the company offers Kentik Detect, a big data-based software-as-a-service that transforms network data into actionable intelligence. This platform enables clients to conduct ad-hoc analytics for improved operations, capacity optimization, anomaly resolution, and DDoS detection, thereby enhancing application and service protection. Kentik also provides My Kentik, a self-service network analytics tool, and an AIOps platform aimed at streamlining network operations. Additionally, the company serves various industries, including financial services, media and entertainment, cloud infrastructure, and telecommunications, offering tailored solutions for visibility, performance, detection, planning, and integration. Kentik was previously known as CloudHelix, Inc. before rebranding in September 2014.

AbCellera

Series B in 2020
AbCellera Biologics Inc. develops antibody discovery platform. Its full-stack, AI-powered drug discovery platform searches and analyzes the database of natural immune systems to find antibodies that can be developed as drugs. The company also develops next-generation transgenic mice that provide a source of fully-human antibodies for the discovery of therapeutic antibody candidates. It has a discovery partnership agreement with Eli Lilly and Company for the discovery of various targets. AbCellera Biologics Inc. was founded in 2012 and is headquartered in Vancouver, Canada.

Carbon Health

Series B in 2020
Carbon Health is a tech-enabled healthcare company founded in 2015 and headquartered in San Francisco, California. It provides a mobile application that facilitates primary care services, allowing users to manage their treatment plans, prescriptions, and lab reports in one place. The company offers omnichannel care through various access points, including clinics, pop-up sites, video consultations, and its application, ensuring convenient and accessible healthcare for patients. Additionally, Carbon Health developed a coronavirus assessment tool and has established COVID-19 testing sites in California, further enhancing its commitment to delivering comprehensive healthcare services.

Pivot Bio

Series C in 2020
Pivot Bio is a biotechnology company founded in 2010 and based in Emeryville, California. The company specializes in advancing crop nutrition through a deep understanding of the microbiome. By leveraging engineering principles and data science, Pivot Bio develops innovative solutions that utilize naturally occurring microbes to enhance crop yield and quality. Their proprietary ON Technology aims to provide essential nutrients to crops, specifically focusing on enabling microbes to fix and supply nitrogen for corn. This approach seeks to offer a sustainable alternative to traditional chemical fertilizers and pesticides, helping farmers improve their yields while addressing the nutritional needs of the growing global population. Through collaboration and communication, Pivot Bio is dedicated to transforming agricultural practices and contributing to a healthier planet.

Biobot Analytics

Seed Round in 2020
Biobot Analytics is a wastewater epidemiology company that is transforming wastewater infrastructure into public health observatories. Its wastewater monitoring technology analyzes urine and stool samples to create a health database that is independent of hospital reporting systems, free from societal biases affecting who can and can’t seek care, and most importantly, rapidly adaptable to new and emerging public health threats.

Unlearn

Series A in 2020
Unlearn is a San Francisco-based company founded in 2017 that specializes in using artificial intelligence to enhance clinical research. It develops innovative software tools aimed at improving clinical trial design, including the creation of Digital Twins to generate Intelligent Control Arms. By utilizing historical datasets and disease-specific machine-learning models, Unlearn produces virtual placebo patients derived from actual patient baseline data, which helps to increase trial power, accelerate timelines, and provide patient-level insights. This approach reduces or eliminates the need for concurrent control arms in clinical studies, streamlining the research process. Unlearn has garnered significant attention, securing $20 million in funding and collaborating with leading pharmaceutical companies. Its work has been recognized in prestigious publications, including a peer-reviewed article in Nature, and it has been acknowledged as a key player in digital health innovation. The company continues to engage with regulators and industry leaders to drive advancements in clinical research through the application of AI technologies.

Halter

Series B in 2020
Halter creates GPS enabled, solar powered collars for cows. The collar hardware allows farmers to use simple tablet app software to remotely set geographic boundaries for cattle, virtual fences. Farmers use Halter's system to avoid physically herding cows, maximizing farmer time and productivity.

AbCellera

Series A in 2020
AbCellera Biologics Inc. develops antibody discovery platform. Its full-stack, AI-powered drug discovery platform searches and analyzes the database of natural immune systems to find antibodies that can be developed as drugs. The company also develops next-generation transgenic mice that provide a source of fully-human antibodies for the discovery of therapeutic antibody candidates. It has a discovery partnership agreement with Eli Lilly and Company for the discovery of various targets. AbCellera Biologics Inc. was founded in 2012 and is headquartered in Vancouver, Canada.

Culture Biosciences

Series A in 2020
Culture Biosciences, founded in 2016 and headquartered in San Francisco, California, specializes in developing automated bioreactors and tools for fermentation. The company provides a digital bio-manufacturing platform that allows biotech companies to optimize their manufacturing processes, enabling them to bring products to market more efficiently. By utilizing robotic sample handling and cloud-based data monitoring and analysis, Culture Biosciences helps scientists run, monitor, and analyze bioreactors more quickly than traditional methods. This innovative approach supports the biotechnology sector in enhancing productivity and streamlining workflows.

C16 Biosciences

Series A in 2020
C16 Biosciences, Inc. manufactures palm oil alternative using microbes and fermenting the palm oil in laboratory. The company manufactures the alternative for the food manufacturers, refiners, traders, and consumers of palm oil. C16 Biosciences, Inc. was founded in 2017 and is based in New York, New York.

evonetix

Series B in 2020
Evonetix Ltd is a biotechnology company based in Little Chesterford, United Kingdom, founded in 2015. The company focuses on developing innovative technology for the parallel synthesis of DNA on silicon arrays, which supports advancements in synthetic biology. Situated within the prestigious Cambridge cluster of high-tech and life science organizations, Evonetix aims to revolutionize DNA synthesis through novel techniques that enhance efficiency and capability. The team at Evonetix comprises experienced professionals from various scientific and engineering disciplines, bringing together a wealth of knowledge to drive the commercialization of their technology.

MycoWorks

Series A in 2020
MycoWorks LLC specializes in the research, design, and manufacturing of sustainable leather alternatives derived from natural mycelium. Established in 2013 and based in San Francisco, the company produces a proprietary material called Reishi, which is water-resistant and customizable in texture and features. Reishi is designed to mimic the performance and feel of traditional leather while being animal-free and environmentally friendly. MycoWorks employs a unique platform known as Fine Mycelium to create this innovative biomaterial, which boasts qualities such as strength, durability, and biodegradability. The company aims to provide natural alternatives to conventional materials like plastic foams, textiles, and leather, catering to industries such as aerospace, automotive, apparel, and architectural interiors. Through its carbon-negative production process, MycoWorks offers a rapidly grown solution that aligns with sustainable design principles.

Advano

Series A in 2020
Advano, operating under NanoStar, Inc., is a New Orleans-based company specializing in silicon nanotechnology. Founded in 2014, Advano develops and produces functionalized silicon nanoparticles and quantum dots for various applications. Notably, its products enhance the energy density of lithium-ion batteries by 30-40%, making them suitable for electric vehicles, consumer electronics, and IoT devices, all without compromising battery life or increasing costs. Additionally, Advano's technology is applied in CO2 carbon capture, super hydrophobic coatings, and printable electronics, serving industries such as telecommunications.

Evolv Technology

Series C in 2020
Evolv Technology specializes in noninvasive body scanners designed for touchless security screening, focusing on enhancing safety in public spaces. The company offers a range of products, including Evolv Express for firearm and bomb detection, Evolv Edge for checkpoint security, and Evolv Pinpoint for facial recognition. These systems are utilized in various settings, such as schools, stadiums, hospitals, and entertainment venues, to ensure the safety of employees, visitors, and VIPs. Founded in 2013 and headquartered in Waltham, Massachusetts, Evolv Technology aims to improve security protocols by integrating advanced sensors and artificial intelligence, enabling reliable scanning without compromising the visitor experience. The company has screened over 50 million individuals, successfully preventing more than 5,000 weapons from entering secure areas. With a leadership team comprising veterans from security agencies, Evolv is committed to providing effective solutions for both government and private sectors.

Novome Biotechnologies

Series A in 2020
Novome Biotechnologies, Inc. is a biotechnology company based in South San Francisco, California, that specializes in engineering bacteria from the human gut to address chronic diseases. Founded in 2015, the company has developed a platform for the controlled colonization of the gut with genetically engineered bacteria, known as Genetically Engineered Microbial Medicines (GEMMs). This innovative approach allows for sustained therapeutic interventions through the precise delivery of microbial activities. Novome's lead preclinical program targets hyperoxaluria by creating a therapeutic strain of bacteria aimed at degrading oxalate to help prevent kidney stone formation. The company is also expanding its synthetic biology platform to explore additional therapeutic applications.

Novome Biotechnologies

Series A in 2020
Novome Biotechnologies, Inc. is a biotechnology company based in South San Francisco, California, that specializes in engineering bacteria from the human gut to address chronic diseases. Founded in 2015, the company has developed a platform for the controlled colonization of the gut with genetically engineered bacteria, known as Genetically Engineered Microbial Medicines (GEMMs). This innovative approach allows for sustained therapeutic interventions through the precise delivery of microbial activities. Novome's lead preclinical program targets hyperoxaluria by creating a therapeutic strain of bacteria aimed at degrading oxalate to help prevent kidney stone formation. The company is also expanding its synthetic biology platform to explore additional therapeutic applications.

Pyka

Seed Round in 2019
Pyka, Inc. specializes in the development of autonomous electric aircraft, primarily aimed at the agricultural sector. Founded in 2016 and headquartered in Oakland, California, the company creates aircraft designed for the application and spraying of chemicals on agricultural lands. These planes are equipped with advanced technology, including autonomous flight controllers, onboard sensors, and systems for obstacle detection and path planning. This enables them to navigate various terrains and perform hyper-short takeoffs and landings from nearly any location. Pyka's aircraft are notable for being the first certified electric autonomous airplanes to operate commercially, providing an innovative and efficient alternative to traditional ground transit in agriculture.

Empirico

Series A in 2019
Empirico is a company focused on developing an insights platform that leverages biological insights derived from human genetics to create new medicines. Its platform utilizes biological datasets and programmable biology to facilitate target discovery and development. This enables scientists to systematically generate, examine, and prioritize high-confidence therapeutic hypotheses, ultimately advancing the field of drug development through innovative approaches grounded in human genetic research.

Capella Space

Series B in 2019
Capella Space is an information services company that provides sub 0.5m very high-resolution synthetic aperture radar earth observation imagery. Through a constellation of small satellites, Capella is providing easy access to frequent, timely, and flexible information affecting dozens of industries worldwide. Capella’s high-resolution SAR satellites are matched with unparalleled infrastructure to deliver reliable global insights that sharpen the understanding of the changing world, improving decisions about commerce, conservation, and well-being on Earth. The company aims to make timely Earth observation an essential tool for commerce, conservation, and well-being. Capella Space was founded in 2014 and based in San Francisco, California.

Alchemab Therapeutics

Seed Round in 2019
Alchemab Therapeutics is developing natural protective antibodies designed to keep people free of hard-to-treat diseases. They are building their transformative engine to identify novel drug targets and develop a broad pipeline of novel antibody therapeutics for hard-to-treat cancers, neurodegenerative conditions, and infectious diseases.

X-37

Series A in 2019
X-37 is a pharmaceutical discovery and development company, which uses advanced artificial intelligence technology from Atomwise, Inc. to discover novel drug candidates by screening vast libraries of chemical compounds against high-value pharmaceutical targets.

Evolv Technology

Series C in 2019
Evolv Technology specializes in noninvasive body scanners designed for touchless security screening, focusing on enhancing safety in public spaces. The company offers a range of products, including Evolv Express for firearm and bomb detection, Evolv Edge for checkpoint security, and Evolv Pinpoint for facial recognition. These systems are utilized in various settings, such as schools, stadiums, hospitals, and entertainment venues, to ensure the safety of employees, visitors, and VIPs. Founded in 2013 and headquartered in Waltham, Massachusetts, Evolv Technology aims to improve security protocols by integrating advanced sensors and artificial intelligence, enabling reliable scanning without compromising the visitor experience. The company has screened over 50 million individuals, successfully preventing more than 5,000 weapons from entering secure areas. With a leadership team comprising veterans from security agencies, Evolv is committed to providing effective solutions for both government and private sectors.

Plotlogic

Seed Round in 2019
Plotlogic Pty Ltd is a Brisbane-based company that specializes in developing advanced ore characterization systems for the mining industry. The firm employs hyperspectral imaging technology through its flagship product, OreSense LV, which identifies variations in a mine's geological model. Additionally, it offers OreBlocks, an API designed to enhance planning processes, and OreCheck, which provides real-time alerts regarding material variations. The technology aims to improve ore recovery and minimize dilution while also reducing carbon emissions and operational costs. Plotlogic's systems are applicable to various commodities, including coal, iron ore, and gold. Founded in 2005, the company is dedicated to offering customized support services alongside its innovative solutions.

Beit

Seed Round in 2019
Beit designs and implements an algorithm for solving a relevant NP-complete class of problems using Quantum Computers, getting speedups better than quadratic, guaranteed by theory. Beit focuses on Hamiltonian cycle problem. NP-complete problems are abstractions relevant for many real world problems encountered in logistics, manufacturing, and warehousing at scale. Beit is headquartered in Kraków, Poland.

Embark Trucks

Series C in 2019
Embark Trucks Inc. develops self-driving truck technology and highway autopilot system for commercial trucking. It designs artificial intelligence software that helps on long haul stretches in the trucking industry. Embark Trucks Inc. was formerly known as Varden Labs Inc. The company was founded in 2015 and is based in San Francisco, California.

Element AI

Series B in 2019
Element AI Inc. provides artificial intelligence solutions (AI) for organizations to identify opportunities to use artificial intelligence and machine learning and build AI solutions. It operates an AI as a Service (AIaaS) platform that enables businesses to launch and incubate AI solutions in partnership with large corporations. The company also operates a research and development laboratory that conducts research to deploy AI in computing infrastructure. It provides its products to insurance, banking and capital markets, manufacturing, logistics, retail, and consumer packaged goods industries. Element AI Inc. was founded in 2016 and is headquartered in Montreal, Canada with an additional office in Toronto, Canada.

Element AI

Series B in 2019
Element AI Inc. provides artificial intelligence solutions (AI) for organizations to identify opportunities to use artificial intelligence and machine learning and build AI solutions. It operates an AI as a Service (AIaaS) platform that enables businesses to launch and incubate AI solutions in partnership with large corporations. The company also operates a research and development laboratory that conducts research to deploy AI in computing infrastructure. It provides its products to insurance, banking and capital markets, manufacturing, logistics, retail, and consumer packaged goods industries. Element AI Inc. was founded in 2016 and is headquartered in Montreal, Canada with an additional office in Toronto, Canada.

PerimeterX

Series C in 2019
PerimeterX, Inc. is a cybersecurity firm that specializes in detecting and preventing automated attacks on web infrastructure. Founded in 2014 and headquartered in San Mateo, California, with additional offices in London, Miami, and Tel Aviv, the company offers a range of security solutions designed to protect organizations from malicious web behavior. Its flagship product, PerimeterX Bot Defender, utilizes behavioral analytics to identify and mitigate various types of bot attacks, including account abuse, web scraping, and marketing fraud. The company also provides specialized solutions for mobile applications and application programming interfaces (APIs), ensuring comprehensive protection across different platforms. Serving industries such as e-commerce, travel, hospitality, and enterprise software, PerimeterX is recognized for its advanced threat protection technology that effectively distinguishes between legitimate users and automated threats.

Tala

Series D in 2019
Tala is a digital finance company that focuses on providing financial services in emerging markets through mobile technology and data science. The company has developed a smartphone app that allows users to access personalized loans, build digital credit histories, and receive instant credit scoring. With over 2 million borrowers, Tala streamlines the loan process from application to fund disbursement and status tracking entirely within the app. Founded in 2011, Tala is headquartered in Santa Monica and operates additional offices in key cities such as Nairobi, Manila, Dar Es Salaam, Mexico City, Mumbai, and Bangalore.