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Theravia is a pharmaceutical company dedicated to developing and commercializing treatments for rare and neglected diseases. The company focuses on addressing unmet medical needs by creating therapies for hereditary metabolic disorders, hematology-oncology, immunology, and gene cell therapy. Through its innovative approach, Theravia aims to provide patients with effective pharmaceutical products that target specific conditions, ultimately improving their health outcomes and quality of life.

Lunaphore specializes in tumor analysis through innovative microfluidic chip technology, which allows for rapid and precise assays that surpass traditional methods. The company's platform facilitates the extraction of spatial proteomic and transcriptome data from tumors and other tissues, transforming standard assays into multiplex spatial biology with a user-friendly interface. This technology aids researchers in immunology, immuno-oncology, and neurology by identifying clinically relevant biomarker signatures, which support the development of diagnostic tools and streamline clinical trials. By improving the efficiency of cancer diagnostics and enhancing the accuracy of results, Lunaphore ultimately aims to contribute to better patient outcomes.

Sirius Medical helps improve healthcare for cancer patients by developing medical devices that aid in surgical treatment. Their objective is to create intuitive and accurate gadgets that allow surgeons and radiologists to provide the finest treatment. Sirius Perception uses audio and visual feedback to provide real-time, directional advice for pinpointing tumors

Magentiq Eye Ltd. is a medical device company based in Haifa, Israel, established in 2014. It specializes in developing advanced technologies for endoscopic procedures, particularly focusing on automatic polyp detection during colonoscopies. The company's flagship product, the Automatic Polyp Detection System (APDS), leverages deep learning and computer vision to enhance the accuracy of polyp identification, thereby reducing the miss rate during examinations. The APDS is available in two formats: APDS-RT, which operates in real-time by processing video feeds from endoscopic cameras, and APDS-OFL, which analyzes pre-recorded colonoscopy videos. Given the prevalence of colonoscopies—approximately 40 million performed annually—the system aims to improve patient outcomes by increasing detection rates and minimizing the risk of interval cancers. Magentiq Eye's technology not only supports physicians in making more informed decisions during procedures but also has the potential for integration with existing endoscopic equipment or as a service model for clinics and hospitals.

Impress is a company that specializes in invisible orthodontics, focusing on personalized teeth alignment services. It offers comprehensive treatments for various dental issues, including unbalanced bites, crowded teeth, rotations, and interdental spaces. Impress is committed to delivering individualized care through tailored diagnoses and treatment plans for each patient. The company also provides digital monitoring services, allowing patients to track their progress remotely. By combining advanced orthodontic solutions with a patient-centric approach, Impress aims to make dental treatment more accessible and affordable.

Inovus Ltd is a company based in Saint Helens, United Kingdom, that specializes in designing and manufacturing medical simulation products aimed at enhancing surgical training. Founded in 2012, the company offers a variety of simulators, including take-home laparoscopic simulators and institutional models, which focus on essential surgical techniques such as laparoscopic appendectomy and cholecystectomy. Inovus Ltd's products are tailored for surgical trainees and residents, providing them with accessible and versatile training options that improve their skills in critical care, medicine, and surgery. The company's commitment to advancing surgical education enables clinicians to deliver better patient care through improved training resources.

Magentiq Eye Ltd. is a medical device company based in Haifa, Israel, established in 2014. It specializes in developing advanced technologies for endoscopic procedures, particularly focusing on automatic polyp detection during colonoscopies. The company's flagship product, the Automatic Polyp Detection System (APDS), leverages deep learning and computer vision to enhance the accuracy of polyp identification, thereby reducing the miss rate during examinations. The APDS is available in two formats: APDS-RT, which operates in real-time by processing video feeds from endoscopic cameras, and APDS-OFL, which analyzes pre-recorded colonoscopy videos. Given the prevalence of colonoscopies—approximately 40 million performed annually—the system aims to improve patient outcomes by increasing detection rates and minimizing the risk of interval cancers. Magentiq Eye's technology not only supports physicians in making more informed decisions during procedures but also has the potential for integration with existing endoscopic equipment or as a service model for clinics and hospitals.

Alesi Surgical Ltd. specializes in the development and commercialization of laparoscopic surgical smoke handling systems aimed at enhancing the safety and outcomes of surgical procedures. Founded in 2009 and based in Cardiff, United Kingdom, the company emerged as a spin-out from the Welsh Institute for Minimal Access Therapy, benefiting from direct access to experienced surgeons and surgical trainers. Alesi Surgical's innovative products are designed to be portable and applicable in both laparoscopic and robot-assisted surgeries. Utilizing electrostatic precipitation technology, these tools effectively eliminate surgical smoke, ensuring a clear visual field during procedures. Alesi Surgical distributes its products to hospitals across Europe, the Middle East, New Zealand, and Australia.

ImaginAb, Inc. is a clinical stage biotechnology company specializing in immune oncology imaging and radiopharmaceutical therapy. Founded in 2007 and headquartered in Inglewood, California, the company develops targeted imaging agents using its proprietary minibody and cys-diabody platforms. Its lead product, the 89Zr crefmirlimab berdoxam (CD8 ImmunoPET™), is currently in Phase II clinical trials and has been licensed by various pharmaceutical and biotech companies for use in their immunotherapy clinical trials. ImaginAb's portfolio includes precision imaging products for different cancers, such as CD8 and CD4 for immune-oncology, as well as PSMA PET for prostate cancer. By providing actionable insights into patient selection and treatment progress, ImaginAb aims to enhance precision medicine in oncology.

Azanta is a privately-owned specialty pharmaceutical company focused on marketing and distributing a range of products aimed at women's health and orphan oncology. Its portfolio includes a variety of specialized medications such as Amnisure, Cicatridina, Repadina Plus, Cystistat, Flexi-T, Methadone, Oxandrin, Suplasyn, and Nimorazole, which serves as a hypoxic radiosensitizer for head and neck cancer patients undergoing radiotherapy. The company also offers Angusta, a medication for labor induction, ensuring accessible health and addiction treatments. Through its diverse product line, Azanta aims to address specific medical needs and improve patient outcomes in targeted therapeutic areas.

Magentiq Eye Ltd. is a medical device company based in Haifa, Israel, established in 2014. It specializes in developing advanced technologies for endoscopic procedures, particularly focusing on automatic polyp detection during colonoscopies. The company's flagship product, the Automatic Polyp Detection System (APDS), leverages deep learning and computer vision to enhance the accuracy of polyp identification, thereby reducing the miss rate during examinations. The APDS is available in two formats: APDS-RT, which operates in real-time by processing video feeds from endoscopic cameras, and APDS-OFL, which analyzes pre-recorded colonoscopy videos. Given the prevalence of colonoscopies—approximately 40 million performed annually—the system aims to improve patient outcomes by increasing detection rates and minimizing the risk of interval cancers. Magentiq Eye's technology not only supports physicians in making more informed decisions during procedures but also has the potential for integration with existing endoscopic equipment or as a service model for clinics and hospitals.

PathoQuest SAS is a biotechnology company that specializes in advanced metagenomics for pathogen detection, having originated as a spin-off from Institut Pasteur. The company utilizes proprietary next-generation sequencing (NGS) technology, which combines innovative sample preparation with a comprehensive database of pathogen genomic information. This approach allows clinicians and biopharmaceutical professionals to enhance the detection of infectious agents in various biological samples. PathoQuest's Viral Safety testing service, aimed at biopharmaceutical companies, represents its first commercial application and has rapidly generated revenue from major industry players. The company's cloud-based bioinformatics platform and automated analysis pipeline further facilitate improved pathogen detection, making its solutions valuable for both clinical and biopharmaceutical quality assurance.

Impress is a company that specializes in invisible orthodontics, focusing on personalized teeth alignment services. It offers comprehensive treatments for various dental issues, including unbalanced bites, crowded teeth, rotations, and interdental spaces. Impress is committed to delivering individualized care through tailored diagnoses and treatment plans for each patient. The company also provides digital monitoring services, allowing patients to track their progress remotely. By combining advanced orthodontic solutions with a patient-centric approach, Impress aims to make dental treatment more accessible and affordable.

SpineGuard is a French medical company focused on the design and production of innovative instruments for spinal surgeries, utilizing its proprietary Dynamic Surgical Guidance (DSG®) technology. This powerful, radiation-free sensing platform enhances the accuracy and safety of skeletal implant placement through real-time audio and visual feedback for surgeons. The company's flagship product, the PediGuard probe, is specifically designed for spine surgery, allowing surgeons to create pilot holes in vertebrae with precision. Equipped with a sensor that measures electrical conductivity, the PediGuard alerts surgeons to changes in bone and tissue types without the need for X-ray imaging. Available in various shapes and sizes, these devices cater to a wide range of surgical needs, from pediatric deformity corrections to adult degenerative conditions. With over 80,000 successful spinal procedures supported by PediGuard and substantial clinical evidence backing its efficacy, SpineGuard aims to address critical challenges in pedicle screw placement while improving patient outcomes and operational efficiency in the surgical environment.

Magentiq Eye Ltd. is a medical device company based in Haifa, Israel, established in 2014. It specializes in developing advanced technologies for endoscopic procedures, particularly focusing on automatic polyp detection during colonoscopies. The company's flagship product, the Automatic Polyp Detection System (APDS), leverages deep learning and computer vision to enhance the accuracy of polyp identification, thereby reducing the miss rate during examinations. The APDS is available in two formats: APDS-RT, which operates in real-time by processing video feeds from endoscopic cameras, and APDS-OFL, which analyzes pre-recorded colonoscopy videos. Given the prevalence of colonoscopies—approximately 40 million performed annually—the system aims to improve patient outcomes by increasing detection rates and minimizing the risk of interval cancers. Magentiq Eye's technology not only supports physicians in making more informed decisions during procedures but also has the potential for integration with existing endoscopic equipment or as a service model for clinics and hospitals.

Nuubo Smart Solutions Technologies, SL is a Spanish medical device company specializing in the design, manufacture, and sale of wearable wireless technologies for cardiac prevention, diagnosis, and rehabilitation. Founded in 2005 and based in Madrid, the company has developed a platform known as the nECG DYNAMIC PLATFORM, which comprises three key components: a biomedical garment that captures electrocardiogram (ECG) signals without disrupting daily activities, a wireless device that continuously records and transmits this data in real time, and analysis software that utilizes artificial intelligence to interpret the ECG information. Nuubo’s products, including the nECG TEXTILE and nECG MINDER, enable prolonged and comfortable heart monitoring, making them suitable for use by professional sports teams and hospitals. The company's innovative approach allows patients to monitor their heart health effectively while maintaining their normal routines.

Pritidenta is a manufacturer of digital dental prosthetic materials designed to deliver aesthetic results through efficient manufacturing and automation processes utilizing CAD/CAM technology. The company offers a range of products, including high-quality zirconia multidiscs and advanced ceramics, as well as chair-side and 3D printing ceramic materials for various dental applications such as crowns, bridges, full contour restorations, veneers, inlays, and onlays. Pritidenta aims to serve the expanding CAD/CAM and 3D printing segments of the dental market, providing innovative solutions to meet the needs of dental professionals.

Caresyntax Inc. is a Boston-based company that provides a digital surgery platform to enhance surgical performance in hospitals and ambulatory surgical centers. Founded in 1991, it leverages data from over 1,600 hospitals globally to deliver insights that improve patient outcomes and operational efficiency. The platform integrates various data sources, including video, audio, clinical, and operational data, enabling real-time analysis and decision-making during surgeries. Caresyntax offers solutions such as qvident, a performance management software, and PRIME365, a comprehensive integration platform that consolidates surgical data and content. With a focus on automating workflows and reducing surgical variability, Caresyntax supports over 4,000 operating rooms and has facilitated millions of surgical procedures worldwide. The company’s HIPAA-compliant software can be deployed on-premise, in the cloud, or in a hybrid format, making it adaptable to diverse healthcare environments.

EBS Technologies GmbH, founded in 2007 and headquartered in Hennigsdorf, Germany, specializes in developing and commercializing medical devices aimed at treating neurologically induced impairments, particularly visual field loss. The company offers EBS Therapy, a non-invasive optic nerve stimulation treatment that utilizes low-voltage electrical currents to promote neuroregeneration and neuroprotection. This therapy targets conditions resulting from stroke, traumatic brain injury, and glaucoma, among others. With over 15 years of research and clinical experience involving more than 1,200 patients, EBS Technologies has demonstrated through double-blind, randomized studies and clinical observations that its therapy can help partially restore vision in affected individuals. The company received the CE Mark for its stimulation device in 2013 and commenced commercial treatments in 2014. Currently, there are eight EBS Treatment centers operating across Germany, with plans to expand the network further.

The Merus corporate growth strategy is driven by a product acquisition plan which employs an opportunistic approach to source product acquisition candidates. This approach allows Merus to source pharmaceutical products across broad therapeutic classes which provides access to acquisition targets not available to other players and creates a diversified strategy. Although Merus has a broad therapeutic focus, opportunities will be pursued if the application of a dedicated small scale sales force can deliver incremental product sales growth. The geographic focus will be the United States and Canada

Collagen Solutions plc is a London-based company that specializes in sourcing, developing, manufacturing, and supplying medical-grade collagen components and biomaterials. Their products are utilized in various applications including regenerative medicine, medical devices, and in-vitro diagnostics across global markets such as Europe, North America, and Asia. The company offers a diverse range of collagen formulations, including soluble collagen, collagen powders, and gels, catering to fields such as orthopaedics, sports medicine, dental care, and cardiovascular surgeries. Additionally, Collagen Solutions provides contract manufacturing services, encompassing technology transfer and regulatory support for collagen-based products. Their expertise extends to creating personalized medical-grade bovine collagen for use as tissue scaffolds in reconstructive and wound care procedures. Established in 2013, Collagen Solutions serves a variety of pharmaceutical and medical device companies, fostering long-term commercial relationships through its comprehensive support and product offerings.

PulseCath is a medical device company that specializes in developing and manufacturing circulatory support systems for cardiologists and cardiac surgeons both in the Netherlands and internationally. The company offers the iVAC 3L, a mid-range heart circulatory assist device capable of generating up to three liters of blood flow per minute. This device provides critical hemodynamic support for patients experiencing left ventricular failure or during high-risk revascularization procedures, particularly when post-cardiotomy weaning complications are a concern. PulseCath's technology can be inserted through the femoral artery, facilitating reliable life support for patients with failing hearts.

SpineVision S.A. is a spinal technology company that specializes in the design, development, and marketing of implants and instrumentation for spinal treatment. Established in 1999 and headquartered in Antony, France, with subsidiaries in Belgium, Italy, the United Kingdom, and the United States, the company focuses on addressing a diverse range of spinal pathologies, including degenerative disc disease, deformities, cervical disorders, trauma, and tumors. Its product portfolio includes advanced systems such as Flex+, X-PLUS, LUMIS, and P.L.U.S., which offer various stabilization options and surgical solutions. Additionally, SpineVision provides specialized systems like the C3 anterior cervical plate and UNI-Thread, enhancing surgical procedures and outcomes. The company's innovations are developed in collaboration with prominent neurological and orthopedic surgeons, resulting in over 20 patents that reflect its commitment to advancing spinal care.

Q3 Medical Devices Limited is an Irish holding company engaged in the development, manufacturing, and distribution of minimally invasive medical devices aimed at treating coronary, peripheral vascular, and non-vascular diseases. Founded in 2013 and headquartered in Dublin, the company operates multiple facilities in Germany. Q3 Medical Devices collaborates with a diverse group of entrepreneurs, manufacturers, distributors, medical professionals, and investors to enhance its capabilities in the medical device sector. The company focuses on acquiring businesses that generate annual revenues between 1 to 10 million, targeting opportunities that expand its manufacturing base, enhance distribution channels, and accelerate the development of its product offerings in minimally invasive treatments.

SpineVision S.A. is a spinal technology company that specializes in the design, development, and marketing of implants and instrumentation for spinal treatment. Established in 1999 and headquartered in Antony, France, with subsidiaries in Belgium, Italy, the United Kingdom, and the United States, the company focuses on addressing a diverse range of spinal pathologies, including degenerative disc disease, deformities, cervical disorders, trauma, and tumors. Its product portfolio includes advanced systems such as Flex+, X-PLUS, LUMIS, and P.L.U.S., which offer various stabilization options and surgical solutions. Additionally, SpineVision provides specialized systems like the C3 anterior cervical plate and UNI-Thread, enhancing surgical procedures and outcomes. The company's innovations are developed in collaboration with prominent neurological and orthopedic surgeons, resulting in over 20 patents that reflect its commitment to advancing spinal care.

Azanta is a privately-owned specialty pharmaceutical company focused on marketing and distributing a range of products aimed at women's health and orphan oncology. Its portfolio includes a variety of specialized medications such as Amnisure, Cicatridina, Repadina Plus, Cystistat, Flexi-T, Methadone, Oxandrin, Suplasyn, and Nimorazole, which serves as a hypoxic radiosensitizer for head and neck cancer patients undergoing radiotherapy. The company also offers Angusta, a medication for labor induction, ensuring accessible health and addiction treatments. Through its diverse product line, Azanta aims to address specific medical needs and improve patient outcomes in targeted therapeutic areas.

Agendia, Inc. is a biotechnology company based in Irvine, California, founded in 2003. The company specializes in developing and distributing genomic-based diagnostic kits aimed at improving cancer treatment for patients. Agendia's molecular diagnostic technology offers insights into a patient's genomic profile, allowing physicians to make informed decisions regarding personalized treatment plans. The company's breast cancer tests utilize a comprehensive analysis of the human genome to evaluate individual risks for metastasis and determine the most appropriate therapies. This includes identifying which patients would benefit from chemotherapy or hormonal treatments, as well as those who may avoid more aggressive interventions in favor of less intensive and cost-effective options.

SuperSonic Imagine SA is a medical technology company that specializes in developing and manufacturing advanced ultrasound imaging systems. Founded in 2005 and headquartered in Aix-en-Provence, France, the company is renowned for its Aixplorer system, which provides high-definition imaging and is particularly effective in diagnosing and monitoring breast, prostate, and thyroid cancers, as well as liver diseases. The Aixplorer system incorporates ShearWave technology, enabling quantitative elastography that measures tissue elasticity. SuperSonic Imagine operates primarily in markets such as China, the United States, and various European countries, distributing its products through a network of offices and distributors. As a subsidiary of Hologic Hub Ltd, the company continues to innovate in the field of medical imaging, enhancing the capabilities of healthcare professionals.

Stanmore Implants Worldwide is an innovative orthopaedic company based in London, UK, specializing in the design and manufacture of bespoke and modular implants for limb-sparing and complex joint replacement procedures. Founded in 1948, the company is recognized for its portfolio of successful orthopaedic implants, including a custom implant service that addresses individual patient needs. Stanmore Implants has also developed advanced technologies, such as ITAP for attaching prosthetics to the skeletons of amputees, and acquired robotic bone preparation technology through its purchase of Acrobot, a firm focused on computer-assisted orthopaedic surgery. In April 2016, Stanmore Implants was acquired by Stryker, further enhancing its capabilities in the orthopaedic market.

Internis Pharmaceuticals Ltd. is a pharmaceutical company based in London, United Kingdom, founded in 2010. The company specializes in the development, manufacture, and supply of prescription vitamin D medicines specifically for the UK market. Its product portfolio includes various formulations of FULTIUM-D3, available in different strengths and forms, as well as ACCRETE-D3, which combines calcium and vitamin D3. These medicines are aimed at preventing and treating common bone disorders such as osteoporosis and vitamin D deficiency, conditions that affect a significant portion of the population. Internis Pharmaceuticals focuses on providing effective solutions to healthcare professionals and patients, addressing the health risks associated with vitamin D deficiency, which can lead to various complications including bone deformities and weakened immune function.

SpineGuard is a French medical company focused on the design and production of innovative instruments for spinal surgeries, utilizing its proprietary Dynamic Surgical Guidance (DSG®) technology. This powerful, radiation-free sensing platform enhances the accuracy and safety of skeletal implant placement through real-time audio and visual feedback for surgeons. The company's flagship product, the PediGuard probe, is specifically designed for spine surgery, allowing surgeons to create pilot holes in vertebrae with precision. Equipped with a sensor that measures electrical conductivity, the PediGuard alerts surgeons to changes in bone and tissue types without the need for X-ray imaging. Available in various shapes and sizes, these devices cater to a wide range of surgical needs, from pediatric deformity corrections to adult degenerative conditions. With over 80,000 successful spinal procedures supported by PediGuard and substantial clinical evidence backing its efficacy, SpineGuard aims to address critical challenges in pedicle screw placement while improving patient outcomes and operational efficiency in the surgical environment.

Medical Vision AB is a medical technology company that specializes in the development, construction, and production of medical devices for endoscopic procedures, particularly in the field of arthroscopic surgery. The company offers a range of products, including arthro-tube devices, arthroscopy pumps, sets, receptacles, digital camera systems, capture devices, fluid management systems, and double pumps. By enhancing visualization during endoscopic surgeries and enabling controlled fluid management within joints, Medical Vision aims to improve patient care quality and increase cost efficiency in healthcare.