Leap Therapeutics
Leap Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, dedicated to acquiring and developing innovative cancer therapies. The company specializes in targeted antibody treatments, focusing on inhibiting tumor-promoting pathways and enhancing immune responses against cancer cells. Its lead program, DKN-01, is a monoclonal antibody that targets Dickkopf-related protein 1 and is currently undergoing clinical trials for various cancers, including esophagogastric, gynecologic, and colorectal cancers. In addition to DKN-01, Leap Therapeutics is developing FL-301, which targets Claudin18.2-expressing cells, as well as two preclinical antibody programs, FL-302 and FL-501. Founded in 2011 and previously known as HealthCare Pharmaceuticals, the company aims to advance therapies that address critical needs in oncology.
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