Diana Cugliari

Managing Director of Accelerator Fund, President and CEO

60 past transactions

Forest Devices

Venture Round in 2020
Forest Devices is a medical device startup that develops a novel stroke screening device designed to detect early signs of stokes.

Neuro Kinetics

Funding Round in 2019
Neuro Kinetics, Inc. provides eye tracking technology and non-invasive neuro-otologic diagnostic testing tools to audiologists, ENT’s, neuro-otologists, neuro-ophthalmologists, and neurologists around the globe.The company also provides maintenance, training, and support services; and accessories.

Clinical Platform

Funding Round in 2019
Clinical Platform creates short form, video based patient and caregiver information for people that have chronic illnesses and then connects them to clinical trials. The purpose of our business is to improve the outcomes of patients by providing easily accessible and retain-able information on the diagnosis of, treatments for and living with and any chronic disease. It is a fact that better educated patients have improved outcomes.

Clinical Platform

Convertible Note in 2017
Clinical Platform creates short form, video based patient and caregiver information for people that have chronic illnesses and then connects them to clinical trials. The purpose of our business is to improve the outcomes of patients by providing easily accessible and retain-able information on the diagnosis of, treatments for and living with and any chronic disease. It is a fact that better educated patients have improved outcomes.

Carmell Cosmetics

Series B in 2017
Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

Ariel Precision Medicine

Convertible Note in 2017
Ariel Precision Medicine is a healthcare company that creates innovative solutions to simplify the personalized treatment of complex disease. It offers clinical decision support tools for the emergency department and the clinic. The company was founded in 2015 and headquartered in Pennsylvania, United States.

Forest Devices

Convertible Note in 2017
Forest Devices is a medical device startup that develops a novel stroke screening device designed to detect early signs of stokes.

Better Body Image

Seed Round in 2016
BBI is committed to assist individuals in achieving their health and fitness goals; it is a body change database that helps start, end, or reverse chronic conditions based on waist size and body measurements. BBI’s new application, “View2Lose”, using its new Patented AI, which demonstrates how an individual will look at the desired weight, keeps its customers motivated towards their desired fitness goals. BBI has partnered with the Australian company AI ventures with a shared mission to make this application global. This joint venture aims to achieve 1 million downloads within the next month after the launch of the app. The immediate objective is to secure a $15 million valuation by early October 2020. This goal is to be realised in collaboration with AI Ventures and Strategikon Health that have invested their AI capabilities, GPU and their marketing resources to bring the business $2 Million in the Series A funding later this year.

Medrobotics

Series G in 2015
Medrobotics is a medical robotics company developing and commercializing the Flex Robotic System. It manufactures and markets the Flex Robotic System, the first robotic surgical platform with a steerable and shapeable robotic scope. Its platform offers surgeons the unique ability to navigate complex anatomy through a single, small entry point while operating in hard-to-reach anatomical locations that might otherwise be inaccessible with straight, rigid surgical tools.

Carmell Cosmetics

Series A in 2014
Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

Cernostics

Series B in 2013
Cernostics is a life science company developing new molecular diagnostic tests for the fight against cancer. Most current diagnostic approaches offer a limited view of cancer because they fail to evaluate the tumor as a system composed of multiple cell types, not merely tumor cells. Its patent-protected technology platform, TissueCypher, uniquely analyzes whole slide digital images with multiplexed fluorescence, providing greater information and accuracy than traditional subjective tissue diagnostics.

Cognition Therapeutics

Venture Round in 2013
Cognition Therapeutics, Inc. is focused on the discovery and development of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of disease targets, and there are currently no therapeutics available to prevent toxic protein accumulation or block their destructive effects. Cognition is founded on the unique combination of biological expertise around these targets, including proprietary assays that emphasize functional responses and proprietary medicinal chemistry that insures novel, high quality small-molecule drug candidates.

ALung Technologies

Series B in 2013
ALung Technologies is a medical device manufacturing company that develops intracorporeal and extracorporeal gas exchange devices for the treatment of acute and chronic respiratory disorders. Its technology utilizes Hemolung, an extracorporeal gas exchange device that circulates blood through a small catheter; and Hattler Catheter, which is placed within the central venous bloodstream in the primary vein that returns blood to the heart and is inserted directly through the skin into the vein. The company was founded in 1997 and headquartered in Pittsburgh, Pennsylvania.

ATRP Solutions

Venture Round in 2013
ATRP SOLUTIONS develops and manufactures specialty polymers that meet their needs. It recognizes the polymeric materials for improving the performance of commercial products in the areas of personal care and cosmetics, detergents and surfactants, paints, pigments, coatings, and biocompatible materials. It was founded in 2006 and is headquartered in Pittsburgh, Pennsylvania.

Cognition Therapeutics

Venture Round in 2012
Cognition Therapeutics, Inc. is focused on the discovery and development of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of disease targets, and there are currently no therapeutics available to prevent toxic protein accumulation or block their destructive effects. Cognition is founded on the unique combination of biological expertise around these targets, including proprietary assays that emphasize functional responses and proprietary medicinal chemistry that insures novel, high quality small-molecule drug candidates.

ClearCount Medical Solutions

Debt Financing in 2012
ClearCount Medical Solutions is the only provider of a sponge management system that combines the benefits of counting and detection. Counts can be quickly reconciled and in the event of a non-reconciliation, a missing sponge can be located using the SmartWandâ„¢. ClearCount innovations bring to market a comprehensive sponge reconciliation and detection solution that improves patient safety and operational efficiency.

Complexa

Series A in 2012
Complexa is a clinical-stage platform biopharmaceutical company researching and developing endogenous human cell signaling technologies targeting an array of prevalent inflammatory, fibrotic, and CNS diseases. The company's proprietary technology involves the synthesis and therapeutic applications of endogenous nitro-fatty acids (NFAs) and additional structure/function-related mediators that are designed to treat various diseases. NFAs are cell-signaling agents that regulate major inflammatory signaling pathways (e.g., Nrf2, NFkB, and HSF). Capitalizing on their identification and synthesis of these endogenous signaling mediators, Complexa's technologies act to amplify the existing anti-inflammatory and metabolic signaling mechanisms that promote the resolution and repair of acute and chronic tissue injury and disease. It is headquartered in Berwyn, Pennsylvania.

Medrobotics

Series C in 2011
Medrobotics is a medical robotics company developing and commercializing the Flex Robotic System. It manufactures and markets the Flex Robotic System, the first robotic surgical platform with a steerable and shapeable robotic scope. Its platform offers surgeons the unique ability to navigate complex anatomy through a single, small entry point while operating in hard-to-reach anatomical locations that might otherwise be inaccessible with straight, rigid surgical tools.

Cognition Therapeutics

Series A in 2011
Cognition Therapeutics, Inc. is focused on the discovery and development of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of disease targets, and there are currently no therapeutics available to prevent toxic protein accumulation or block their destructive effects. Cognition is founded on the unique combination of biological expertise around these targets, including proprietary assays that emphasize functional responses and proprietary medicinal chemistry that insures novel, high quality small-molecule drug candidates.

Rinovum Women's Health

Venture Round in 2010
Rinovum Women's Health, Inc. develops medical devices for women. It offers Stork, a medical device that aids in natural fertility and conception in the privacy of home.

STARR Life Sciences

Venture Round in 2010
STARR Life Sciences values its medical research customers and is dedicated to developing quality new products specifically designed for mice, rats and other small animals.
AppCompTech is a software development company focused on a life sciences application in Radiation Treatment Planning for Cancer Therapy. In 2010 an estimated 1.4 million Americans will be diagnosed with cancer and approximately 65% of those cancer victims will receive some form of radiation therapy.
NeuroInterventional Therapeutics, Inc. ("NIT", dba Neurointerventions, Inc.) is a Pittsburgh-based company which designs and manufactures advanced catheter systems used to find, trap, and extract thrombus ("blood clots") in a wide range of cerebral vessels, thereby increasing chances of survival and minimizing disability.

Cernostics

Series A in 2010
Cernostics is a life science company developing new molecular diagnostic tests for the fight against cancer. Most current diagnostic approaches offer a limited view of cancer because they fail to evaluate the tumor as a system composed of multiple cell types, not merely tumor cells. Its patent-protected technology platform, TissueCypher, uniquely analyzes whole slide digital images with multiplexed fluorescence, providing greater information and accuracy than traditional subjective tissue diagnostics.

Celsense

Debt Financing in 2010
Celsense is a privately held biotechnology company offering novel MRI agents that allow scientists and clinicians to monitor the location and quantity of transplanted cells. The company's products have applications in the fields of regenerative medicine, immunotherapy, and the study of inflammation and immune system response. Celsense is currently collaborating with leading pharmaceutical and biotechnology organizations and is developing products suitable for human use.

Saladax Biomedical

Series C in 2010
Saladax develops rapid blood tests for point-of-care and for laboratory analyzers for use in psychiatry and oncology. The firm has been supplying laboratories and clinicians worldwide with revolutionary diagnostic solutions for more than 15 years.

Cellumen

Venture Round in 2010
Cellumen is the innovator in cellular systems biology (CSB™) solutions providing the most accurate predictions of drug efficacy and safety, thus reducing failure rates and cutting development costs. Cellumen’s CSB solutions are driving Discovery Toxicology by addressing the full complexity of disease and safety. Leading global organizations, such as the Mayo Clinic, Hamamatsu Photonics K.K., the EPA, FDA, NIH and top pharmaceutical companies, partner with Cellumen. Cellumen is a partner company of Safeguard Scientifics.

PeriOptimum

Seed Round in 2010
PeriOptimum provides workflow management solutions and consulting services for the healthcare industry. It offers real-time technology and process management solutions that allow hospitals to improve workflow in the operating room environment and also enables doctors, nurses, and managers to access patient location and clinical information. The company’s solution portfolio includes RealView, a real time workflow management system that allows users to see patient status in real-time and in multiple views; PeriOperative Improvement Evaluation, a process evaluation solution for on-site analysis and off-site data extraction and analysis; Surgical Analytics Services, a service to isolate, analyze, benchmark, and improve indicators; and Surgical Capacity Improvement Program, a process improvement program for the perioperative process. It also provides PeriOp Education Services, a program that enables hospitals to train their new recruits on critical topics and orient them on the hospital's perioperative department; PathFinder, an RFID-based tracking, workflow management, and communications system; and data analytics and workflow reengineering services.

ThermalTherapeuticSystems

Series A in 2009
ThermalTherapeutic Systems was founded in June, 2006 by a team of highly respected experts in the field of hyperthermic perfusion technology, medical device manufacturing, molecular diagnostics and technology commercialization.

Medrobotics

Series A in 2009
Medrobotics is a medical robotics company developing and commercializing the Flex Robotic System. It manufactures and markets the Flex Robotic System, the first robotic surgical platform with a steerable and shapeable robotic scope. Its platform offers surgeons the unique ability to navigate complex anatomy through a single, small entry point while operating in hard-to-reach anatomical locations that might otherwise be inaccessible with straight, rigid surgical tools.

Cognition Therapeutics

Series A in 2009
Cognition Therapeutics, Inc. is focused on the discovery and development of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of disease targets, and there are currently no therapeutics available to prevent toxic protein accumulation or block their destructive effects. Cognition is founded on the unique combination of biological expertise around these targets, including proprietary assays that emphasize functional responses and proprietary medicinal chemistry that insures novel, high quality small-molecule drug candidates.

Caliber Infosolutions

Seed Round in 2009
Caliber Infosolutions Inc. is Pittsburgh PA based global company, focused on solutions for Quality Management specially in Pharma and other regulated industries. Thier highly successful flagship product CaliberLIMSTM is treated as a great asset by their end users.

Saladax Biomedical

Series A in 2008
Saladax develops rapid blood tests for point-of-care and for laboratory analyzers for use in psychiatry and oncology. The firm has been supplying laboratories and clinicians worldwide with revolutionary diagnostic solutions for more than 15 years.

Lipella Pharmaceuticals

Seed Round in 2008
Lipella Pharmaceuticals is a biotechnology company that develops products for intravesical therapy. It is a method of providing local treatments directly to the urinary bladder lumen via urethral catheterization. Indications they target include interstitial cystitis (also known as painful bladder syndrome), overactive bladder, and superficial bladder cancer. Interstitial cystitis is a chronic, painful, inflammatory condition of the bladder wall that affects over 1 million people in the United States. Its cause is unknown and there is no cure. Treatment options exist, but a majority of cases are refractive to existing therapies.

Carmell Cosmetics

Seed Round in 2008
Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

ParentPlus

Seed Round in 2007
ParentPlus was formed to alleviate male-factor subfertility by bringing innovative biotechnology to millions of subfertile couples for whom intra-uterine insemination (IUI) might be an appropriate therapy. This therapy, with spousal or donor sperm, is underutilized ― perhaps in part because it is not typically discussed in the popular press.

Cognition Therapeutics

Seed Round in 2007
Cognition Therapeutics, Inc. is focused on the discovery and development of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of disease targets, and there are currently no therapeutics available to prevent toxic protein accumulation or block their destructive effects. Cognition is founded on the unique combination of biological expertise around these targets, including proprietary assays that emphasize functional responses and proprietary medicinal chemistry that insures novel, high quality small-molecule drug candidates.

Crystalplex

Seed Round in 2007
Crystalplex provides cutting-edge fluorescent nanoparticle technology to the biomedical research, molecular diagnostic, and pathology markets. The company products provide test results from smaller samples and with reduced time, lower labor costs, and less expensive instrumentation than currently possible. It also provides better results for drug discovery and diagnostic decision making. Crystaplex specializes in the cost-effective manufacturing of the most robust Quantum Dots available for illumination and solar energy applications. The proprietary technology in their SapphireTM QDs provides a stable crystal design, flexible polymer matrix morphology, and meets environmentally responsible yet demanding performance requirements for high-end consumer electronics applications such as LCD TVs, displays, and high-CRI architectural lighting. Crystaplex was founded in 2004 and is headquartered in Pittsburgh, Pennsylvania.

Applied Isotope Technologies

Seed Round in 2007
Applied Isotope Technologies, Inc. creates new technologies, measurement tools, products, and services for environmental and biological analyses. It manufactures and sells isotopic spikes, ESIS-keyed software and reagent kits. The company sells a variety of individual products for environmental analysis, including spiked and natural analytical standards, reagents, isotope spikes, matrices, and sample extraction tools. It also provides advice, information, and technical support, as well as isotope dilution mass spectrometry (IDMS)/speciated isotope dilution mass spectrometry (SIDMS) testing products that enable environmental analytical laboratories to implement speciated analyses using IDMS and SIDMS methods. In addition, the company offers reagent kits for speciated analyses of various difficult-to-measure metal toxins, such as chromium and mercury. Applied Isotope Technologies was founded in 2003 and is based in Pittsburgh, Pennsylvania.

Separation Design Group

Seed Round in 2007
Separation Design Group offers miniature oxygen generators operating at faster cycle times, resulting in a more energy-efficient device. The company was founded in 2003 and is based in Waynesburg, Pennsylvania.

Intelomed

Pre Seed Round in 2007
Intelomed is a company dedicated to improving cardiovascular system monitoring, thereby enhancing patient outcomes through noninvasive, real-time monitoring of the cardiovascular system. It specializes in the fields of biotechnology, healthcare, and medical device.

ChemDAQ Inc.

Venture Round in 2007
ChemDAQ, Inc. manufactures gas detection systems for protection of personnel exposed to toxic sterilant gases. The company offers ChemDAQ sterilant gas monitoring system; and ChemDAQ data acquisition module, which provides the means of monitoring, displaying, and documenting the sterilant gas levels. It serves hospitals and various organizations. ChemDAQ, Inc. was founded in 1996 and is based in Pittsburgh, Pennsylvania.

Celsense

Pre Seed Round in 2007
Celsense is a privately held biotechnology company offering novel MRI agents that allow scientists and clinicians to monitor the location and quantity of transplanted cells. The company's products have applications in the fields of regenerative medicine, immunotherapy, and the study of inflammation and immune system response. Celsense is currently collaborating with leading pharmaceutical and biotechnology organizations and is developing products suitable for human use.

StageMark

Series B in 2007
StageMark develops and markets inflammatory diseases identification and monitoring solutions. The company's product, CB-CAPs, enables user to analyze complement products bound to various blood cell types such as erythrocytes, platelets, reticulocytes, and lymphocytes. StageMark, Inc. was founded in 2004 and is headquartered in Pittsburgh, Pennsylvania.

STARR Life Sciences

Venture Round in 2006
STARR Life Sciences values its medical research customers and is dedicated to developing quality new products specifically designed for mice, rats and other small animals.

Lipella Pharmaceuticals

Seed Round in 2006
Lipella Pharmaceuticals is a biotechnology company that develops products for intravesical therapy. It is a method of providing local treatments directly to the urinary bladder lumen via urethral catheterization. Indications they target include interstitial cystitis (also known as painful bladder syndrome), overactive bladder, and superficial bladder cancer. Interstitial cystitis is a chronic, painful, inflammatory condition of the bladder wall that affects over 1 million people in the United States. Its cause is unknown and there is no cure. Treatment options exist, but a majority of cases are refractive to existing therapies.
AppCompTech is a software development company focused on a life sciences application in Radiation Treatment Planning for Cancer Therapy. In 2010 an estimated 1.4 million Americans will be diagnosed with cancer and approximately 65% of those cancer victims will receive some form of radiation therapy.

RedPath Integrated Pathology

Pre Seed Round in 2006
RedPath Integrated Pathology, LLC operates as a reference laboratory and provides support services for oncology cases. It offers PathFinderTG, a testing platform for resolving diagnoses from the original pathology specimen. The company serves pathologists, clinicians, and patients. RedPath Integrated Pathology, LLC was founded in 2004 and is headquartered in Pittsburgh, Pennsylvania.

Immunetrics

Seed Round in 2006
Immunetrics is a biosimulation company established to direct mechanistic modeling against the increasing challenges of drug discovery and development.

Diamyd Medical

Pre Seed Round in 2006
Diamyd Medical develops the diabetes vaccine Diamyd®, an antigen-specific immunotherapy based on the exclusively licensed GAD-molecule. GABA constitutes alongside with the diabetes vaccine a key asset in Diamyd Medical and the Company uses its GABA in-licensed technology to develop a proprietary GABA drug product. Diamyd Medical’s shares are traded on Nasdaq Stockholm First North, ticker DMYD B.

StageMark

Venture Round in 2006
StageMark develops and markets inflammatory diseases identification and monitoring solutions. The company's product, CB-CAPs, enables user to analyze complement products bound to various blood cell types such as erythrocytes, platelets, reticulocytes, and lymphocytes. StageMark, Inc. was founded in 2004 and is headquartered in Pittsburgh, Pennsylvania.

Applied Isotope Technologies

Seed Round in 2006
Applied Isotope Technologies, Inc. creates new technologies, measurement tools, products, and services for environmental and biological analyses. It manufactures and sells isotopic spikes, ESIS-keyed software and reagent kits. The company sells a variety of individual products for environmental analysis, including spiked and natural analytical standards, reagents, isotope spikes, matrices, and sample extraction tools. It also provides advice, information, and technical support, as well as isotope dilution mass spectrometry (IDMS)/speciated isotope dilution mass spectrometry (SIDMS) testing products that enable environmental analytical laboratories to implement speciated analyses using IDMS and SIDMS methods. In addition, the company offers reagent kits for speciated analyses of various difficult-to-measure metal toxins, such as chromium and mercury. Applied Isotope Technologies was founded in 2003 and is based in Pittsburgh, Pennsylvania.

Proteopure

Pre Seed Round in 2006
Proteopure offers protein isolation solutions for proteomic results. The company provides a universal method for isolating proteins. Its sample preparation kit uses a protein capture technology, and can specifically separate out proteins from various contaminants, including salts, nucleic acids, and detergents. Proteopure is headquartered in Pittsburgh, Pennsylvania.

Blue Belt Technologies

Pre Seed Round in 2006
Blue Belt Technologies is a medical device company that focuses on technology and capabilities of surgical instrumentation. They proprietary technology can improve minimally invasive techniques in orthopedics, providing physicians with consistency and accuracy through a myriad of intelligent hand-held tools. It also enables the development of more advanced solutions to patients’ problems. Blue Belt Technologies was acquired by Smith & Nephew on January 5m 2016. The company was founded in 2003 and is headquartered in Pennsylvania, USA.

MedSage Technologies

Pre Seed Round in 2004
medSage Technologies provides software and services which enable providers in the rapidly growing home medical equipment industry.
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