Gradient’s mission is to cool the world by transforming every home to be more comfortable and healthy for the people who inhabit it — without compromising the environment. Today, heating and cooling equipment emits more greenhouse gas emissions than the entire transportation sector, and expansion in the use of cooling is projected to double these emissions in the next 30 years. However, comfortable buildings are critical for health and productivity, especially among communities that are vulnerable to the effects of climate change. Gradient’s vision is a future where everyone has access to comfortable buildings that are fully decarbonized. Our launch product is a direct-to-consumer high-efficiency and low-carbon heat pump.
Finwave Semiconductor develops a 3DGaN technology designed to enhance 5G devices.
Quaise is an energy company that is developing and commercializing novel millimeter-wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today. The company was founded in 2018 and is based in Cambridge, Massachusetts.
Foundation Alloy leverage advanced materials technology to design novel alloys optimized for additive manufacturing.
Seaspire Skincare is into manufacturing multifunctional colorants and actives influenced by the biodiversity of the ocean.
Agility Robotic's legged locomotion expertise is built on a history of academic research, including the bipedal walking and running robot ATRIAS. Agility Robotics is leveraging this work to create products that address the real world needs of rugged, efficient, and highly capable mobility platforms.
Concerto Biosciences rebuilds microbial communities in, on, and around us to heal our bodies and our planet. Products that rebuild microbial communities do not yet exist because no one can map the vast inter-species interaction networks responsible for community behavior. Concerto’s cofounders therefore invented the first-ever ultra-high-throughput platform to experimentally measure millions of microbial interactions. Concerto maps interaction networks that reveal a new class of products called “ensembles”—combinations of microbes that work in concert to shepherd damaged microbial communities to health. The opportunities are enormous: Concerto will become the premier inventor of ensembles across medicine and agriculture, reinventing humanity’s relationship with microbes.
Gelmedix is a developer of a biomaterial platform to improve drug delivery for complicated ophthalmic treatment. The company's platform offers a single non-invasive gel patch that can be used as a drug-eluting sealant with tissue adhesion, tunable drug elution, and biocompatibility properties, thereby enabling healthcare providers to reduce the usage of drops which cause inconvenience to patients.
RightHand Robotics provides end-to-end solutions that reduce the cost of e-commerce order-fulfillment of electronics, apparel, grocery. Their robots grasp a wide variety of items from bins and cases. Their core technology enables them to do this automatically without laborious data entry or parameter-tuning — so they are inexpensive to set up and flexible to the changing needs of businesses. The company was founded in 2015 and is headquartered in Somerville, Massachusetts.
Tender Food is a food technology startup that specializes in creating plant-based and cultured meat products. The company was founded by researchers from Harvard University and has developed novel fiber production technology to spin plant proteins into fibrous structures that mimic the texture and mouthfeel of real meat. Their innovative approach involves using natural proteins to create realistic textures in alternative meats.
Quaise is an energy company that is developing and commercializing novel millimeter-wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today. The company was founded in 2018 and is based in Cambridge, Massachusetts.
MicroByre is a platform for bacterial domestication. Their automated characterization pipeline gathers the oft-overlooked data that highlights unleveraged bacteria that meet functional industrial criteria. That is, they rapidly find the bacteria with naturally unfussy eating habits and evolution-honed metabolisms that have the potential to convert unrefined biomasses into commodity chemicals at vastly improved efficiencies compared to extant fermentation processes. They select from these functionally de-risked bacteria those which can be directly genetically modified to improve their cost profiles — even if they have never been engineered before. The data from our unique characterization pipeline informs the minimally precise genetic modifications necessary to increase pliability and yield, eliminate nutritional additives, maximize feedstock utilization, and improve contamination tolerance & phage resistance. MicroByre gives biomass conversion a truly competitive edge against petrochemical synthesis. MicroByre’s platform bridges the gap between the promising and the profitable in synthetic biology and bioengineering. A unique combination of resources and skills makes MicroByre a valuable potential partner for companies of all sizes and industries. They collaborate to define project scope to match a mutually agreeable business model, which could be a fee for service, license agreement, or joint development agreement.
Via Separations is enabling industrial decarbonization with its novel chemistries that allow manufacturing facilities to slash their energy consumption while making more product. Targeting the 12% of US energy consumption that is wasted each year separating chemicals, Via reduces the load of the process by 90%, electrifies the most energy-intensive step in chemical production, and generates additional revenue for the customer. Today, Via is deploying its technology in pilot trials at pulp & paper facilities to eliminate 100 million metric tons of CO2 by 2050. Via’s innovation is a highly selective and robust membrane filter that replaces the energy-inefficient heat-based separations in industrial processes. Spun out of MIT’s Department of Material Science & Engineering, Via has scaled up the technology by more than 10 million times and demonstrated working prototypes at a commercial scale.
Verve Motion develops exo-suits to aid workers in physically demanding tasks. The company focuses on lightweight wearables to power the human workplace.
Ubiquitous Energy is the world leader in transparent photovoltaics. Its award-winning technology is the world’s only truly transparent solar product. UE technology harvests solar energy and serves as an invisible, onboard source of electricity for a variety of end products. The thin coating can be applied to the surface of windows glass to provide electricity generation and energy efficiency while remaining visibly indistinguishable from the fully transparent standard windows on the market today. Originally spun out of MIT, Ubiquitous Energy is now producing its highly transparent, efficient solar cells and windows in its production facility in Silicon Valley.
Clerio Vision is a medical device company that specializes in the fields of refractive, laser, ophthalmic, medical device, contact lenses, and intraocular lenses. The company is in process of developing and commercializing a portfolio of next-generation products in contact lenses. Clerio Vision was founded in 2014 and headquartered in Rochester, New York.
Swift Solar is a company focused on developing advanced solar technology. The company's core innovation is perovskite solar cells, designed to be more efficient and affordable than traditional solar panels. Swift Solar emphasizes domestic manufacturing and abundant raw materials to ensure scalability.
Concerto Biosciences rebuilds microbial communities in, on, and around us to heal our bodies and our planet. Products that rebuild microbial communities do not yet exist because no one can map the vast inter-species interaction networks responsible for community behavior. Concerto’s cofounders therefore invented the first-ever ultra-high-throughput platform to experimentally measure millions of microbial interactions. Concerto maps interaction networks that reveal a new class of products called “ensembles”—combinations of microbes that work in concert to shepherd damaged microbial communities to health. The opportunities are enormous: Concerto will become the premier inventor of ensembles across medicine and agriculture, reinventing humanity’s relationship with microbes.
Humanyze helps companies improve by understanding their people. Performance cannot be reflected solely by a balance sheet. With unmatched technology from the MIT Media Lab, we combine wearable sensors and digital data to deliver people analytics and insights to our customers.
Tender Food is a food technology startup that specializes in creating plant-based and cultured meat products. The company was founded by researchers from Harvard University and has developed novel fiber production technology to spin plant proteins into fibrous structures that mimic the texture and mouthfeel of real meat. Their innovative approach involves using natural proteins to create realistic textures in alternative meats.
Agility Robotic's legged locomotion expertise is built on a history of academic research, including the bipedal walking and running robot ATRIAS. Agility Robotics is leveraging this work to create products that address the real world needs of rugged, efficient, and highly capable mobility platforms.
5x5 Technologies is a leader in data analytics, enabling owners of critical infrastructure to optimize performance and revenue at-scale. Leading companies, systems integrators, and governmental agencies trust 5x5 for AI-powered analytics, data integrity, 3D digital twins and system integrations. Our award-winning firm is backed by Softbank Corp., Safar Partners, Hostplus, Ocean Azul Partners, Council Tree Investors, innovation-driven family offices and individual investors. 5x5 has employees based in North and Central America, Europe and Asia.
Radical Plastics is a radical solution to plastic pollution.
Cogito is a computer service company that enhances the emotional intelligence of phone professionals by applying behavioral science through artificial intelligence and machine learning. Its software evaluates hundreds of behavioral signals through voice to provide live conversation coaching for agents and a real-time measure of customer experience for every call.
RightHand Robotics provides end-to-end solutions that reduce the cost of e-commerce order-fulfillment of electronics, apparel, grocery. Their robots grasp a wide variety of items from bins and cases. Their core technology enables them to do this automatically without laborious data entry or parameter-tuning — so they are inexpensive to set up and flexible to the changing needs of businesses. The company was founded in 2015 and is headquartered in Somerville, Massachusetts.
Quaise is an energy company that is developing and commercializing novel millimeter-wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today. The company was founded in 2018 and is based in Cambridge, Massachusetts.
Gelmedix is a developer of a biomaterial platform to improve drug delivery for complicated ophthalmic treatment. The company's platform offers a single non-invasive gel patch that can be used as a drug-eluting sealant with tissue adhesion, tunable drug elution, and biocompatibility properties, thereby enabling healthcare providers to reduce the usage of drops which cause inconvenience to patients.
Commonwealth Fusion is a research company that develops energy through an inexhaustible power plant. It uses rare-earth barium copper oxide superconductor technology to develop energy. They combine proven physics backed by decades of government-funded fusion research with a revolutionary superconducting magnet technology to accelerate the path to commercial fusion energy Commonwealth Fusion Systems (CFS) is on track to bring fusion energy technology to the market. CFS was spun out of MIT and is collaborating with MIT’s Plasma Science and Fusion Center to leverage decades of research combined with the innovation and speed of the private sector. The business designs and builds fusion machines that deliver limitless and clean fusion energy and integrate proven physics with magnet technology, allowing clients to contribute to the expansion of renewable energy while mitigating the effects of climate change.
Nelumbo is commercializing a new platform of structural materials. The company’s current focus is on developing improved heat exchangers for the HVAC market. Our ability to improve energy performance and minimize corrosion in a single platform unlocks mass market opportunity with potential for significant carbon emission and energy use reductions worldwide.
Kebotix is a high-tech materials discovery and production company. It is to reinvent the materials industry and enable a new age of discovery of new materials using AI, machine learning, and robotics. It was founded in 2017 and is headquartered in Cambridge, Massachusetts.
EagleDream Technologies is a veteran-owned organization comprised of individuals with long-tenured relationships in information technology. Formed in 2013, the team has broad experience in conquering business challenges with innovative solutions and deep expertise. EagleDream believes the most disruptive technology is world-class customer service, and although they offer many services, they believe in serving people first, and through that they produce quality work.
Honeoye Remedies provides all-natural skincare products meant for cosmetic use. The highest quality ingredients are used backed by laboratory testing for effective and safe alternatives.
Verve Motion develops exo-suits to aid workers in physically demanding tasks. The company focuses on lightweight wearables to power the human workplace.
Aramis Biosciences provides disease-modifying therapy for ocular surface disease and is an immuno-ophthalmology biopharmaceutical company. For inquiries, email, telephone numbers, and physical addresses are available on their website.
Health Care Originals develops and offers products for the management of chronic respiratory diseases. The company offers ADAMM, a three-part solution comprising a wearable device, smartphone application, and web portal to identify and monitor precursor symptoms of asthma attacks. Health Care Originals was founded in 2014 and is based in New York, United States.
Clerio Vision is a medical device company that specializes in the fields of refractive, laser, ophthalmic, medical device, contact lenses, and intraocular lenses. The company is in process of developing and commercializing a portfolio of next-generation products in contact lenses. Clerio Vision was founded in 2014 and headquartered in Rochester, New York.
C2Sense is currently working to bring two products to market: Halo Diagnostics, a digitally connected immunoassay reader with a user-friendly hardware and software, provide near-PCR sensitivity to address the gap in the patient-to-provider workflow. The Halo hardware is supported by a cloud-based, HIPAA compliant software solution that provides real-time test results to patients using an app (iOS/Android) or a web portal and, simultaneously, can be shared with a Telehealth physician to expedite time sensitive therapeutic prescriptions. To rapidly scale this technology, C2Sense partners with with immunoassay test manufacturers that own large portfolios of antigen tests that, pre-pandemic, had been exclusively providing tests to hospitals and urgent care facilities. By pairing these tests with a digitally enabled, highly sensitive test readers, remote physicians have access to store and review the same test results their patients are seeing in real time. In conjunction with Halo, C2Sense has designed different sensing solutions to provide product quality information and counterfeit detection from the point of manufacturing out to the customer. Discretely printed onto or included in a product, the tags are safe, versatile molecular additives that instantaneously report valuable information about the status of a good. They identify counterfeits and, where required, they are designed to react to problems encountered in the distribution chain (temperature change, oxygen sensing, and more). The tags are compatible with products as small as a pill, or can coat entire packaging surfaces, enabled by the tags’ compatibility with a myriad of printing and coating techniques.
Via a combination of materials, biotechnology and optics IP, we are developing a microbiological testing solution applicable to pathogens, allergens and spoilage organisms. The core technology enables quantitative and array-based tests for high throughput, low component and overall solution cost, best in class time-to-result, and a hardware design road-map including small footprint and handheld form factors. The combination of consumables incorporating our proprietary materials and biological agents, low-cost hardware and analytics we're developing is uniquely positioned to serve the market.
Lucy Therapeutics is a biotech company providing effective treatments for neurological diseases start with the mitochondria. The company is offering a differentiated approach to drug discovery by drugging targets associated with early disease pathogenesis. The company's approach can also be expanded to provide new options for treating similar neurologically focused diseases including Parkinson's Disease (PD) and Alzheimer's Disease (AD).
Gradiant Energy Services is an oilfield services company addressing industry’s toughest water challenges through custom-engineered solutions and game-changing technologies. We serve oil and gas operators seeking safe, reliable, economic, environmental and efficient treatment, reuse and recycling of flowback and produced water.
Swift Solar is a company focused on developing advanced solar technology. The company's core innovation is perovskite solar cells, designed to be more efficient and affordable than traditional solar panels. Swift Solar emphasizes domestic manufacturing and abundant raw materials to ensure scalability.
Kebotix is a high-tech materials discovery and production company. It is to reinvent the materials industry and enable a new age of discovery of new materials using AI, machine learning, and robotics. It was founded in 2017 and is headquartered in Cambridge, Massachusetts.
Liquid X is an electronic company that enables users to print metal traces and films that deliver results comparable to the bulk metal. The company partners with manufacturers within the electronics industry to develop and print functional components utilized in various devices, including sensors; heating elements; smart textiles, and many others. Liquid X inks are unique because, unlike other metallic conductive inks, their products contain actual metal atoms, not nanoparticles or metal flakes. The processing parameters of Liquid X metallic inks are attractive due to the low conversion temperatures and short processing times. The resulting films or traces exhibit desirable characteristics such as high conductivity, thin and precise features, and excellent adhesion. An advantage of the low temperature processing is the ability to use of a wide range of substrates from fibrous materials such as paper and gauze to flexible, organic material such as plastics. In addition, low viscosity provides the opportunity for the use of a variety of deposition methods such as inkjet, slot die, flexography, offset, and gravure.