Gradient, also known as Treau, Inc., is a company based in San Francisco, California, that specializes in designing and developing environmentally friendly heating and air conditioning solutions for residential use. Founded in 2017, Gradient focuses on creating products that not only improve energy efficiency but also enhance user experience and ease of installation. The company's mission centers on providing innovative climate control systems that align with a sustainable future, making them a compelling option for homeowners seeking more pleasant and responsible alternatives to traditional heating and cooling systems.
Finwave Semiconductor specializes in the development of advanced gallium nitride (GaN) transistors and integrated circuits (ICs) tailored for 5G communications and power conversion applications. The company utilizes a unique 3DGaN technology, specifically its differentiated fin field-effect transistor (FinFET) design, to enhance the performance of high-volume applications such as radio frequency front end (RFFE) systems for mobile devices. This innovative approach allows Finwave to create semiconductor materials with distinct properties, contributing to advancements in electronics and energy management.
Quaise is an energy company pioneering millimeter wave drilling technology to access deep geothermal energy. Quaise is developing and commercializing novel millimeter wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today.
Foundation Alloy leverage advanced materials technology to design novel alloys optimized for additive manufacturing.
Seaspire Skincare specializes in the development and manufacturing of multifunctional colorants and active ingredients derived from oceanic biodiversity. The company focuses on creating innovative solutions to address chronic and cosmetic hair and skin conditions while aiming to replace harmful components in traditional sunscreens. One of its key products features the biomolecule Xanthochrome, which provides enhanced protection against a wider spectrum of ultraviolet radiation compared to existing physical and chemical filters. This technology is designed for preventative skincare, promoting a healthier approach that minimizes adverse effects on both human and marine health. Through its sustainable and less toxic formulations, Seaspire Skincare contributes to advancing the skincare industry towards safer and environmentally friendly practices.
Agility Robotics Inc. is a robotics development company founded in 2015 and based in Albany, Oregon. It specializes in designing and developing bipedal robots, notably Cassie, which is capable of walking and running. The company leverages its expertise in legged locomotion, rooted in extensive academic research, to create robots that serve as mobile sensor platforms and can operate in real-world environments. Agility Robotics aims to produce efficient, agile, and robust mobility solutions that can work alongside humans in various settings, such as offices, factories, and homes. Its technology enables clients to automate tasks in diverse terrains with minimal programming, addressing the practical needs of academic, corporate, and military sectors.
Concerto Biosciences discovers and develops specific combinations of microbial ensembles. Using kChip, a patented, high-throughput platform that constructs and screens millions of defined microbial communities - Concerto creates massive data sets on how microbes function when growing in complex communities. From these data, Concerto directly discovers microbial ensembles that perform a desired task and learns design rules for ensemble engineering.
Developer of a light-activated biomaterial platform designed to bring innovation in ocular and regenerative therapies. The company's platform focuses on bio-adhesion, tissue regeneration, tunable mechanics, and therapeutic loading across modalities from small molecules to cell and gene therapies through its photo crosslinked hydrogels, providing medical professionals to perform cell-based therapies for vision restoration, intraocular sustained release of small molecules and peptides, and in situ forming bioadhesives.
RightHand Robotics, Inc. specializes in manufacturing robotic order-picking systems designed for various industrial applications, including e-commerce, food handling, and flexible manufacturing. The company offers innovative products such as the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that enhances the robots' ability to grasp items gently and make adjustments to avoid errors. Their technology allows robots to automatically grasp a wide range of items from bins and cases, eliminating the need for extensive data-entry or parameter-tuning, thereby making the systems cost-effective and adaptable to the evolving needs of businesses. Founded in 2015, RightHand Robotics is headquartered in Cambridge, Massachusetts, with a sales and business development office located in Frankfurt, Germany.
Boston Meats, Inc. produces alternative meat products using proteins. It also develops fiber production technology to produce meats using natural proteins. The company was founded in 2020 and is based in Somerville, Massachusetts.
Quaise is an energy company pioneering millimeter wave drilling technology to access deep geothermal energy. Quaise is developing and commercializing novel millimeter wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today.
MicroByre, Inc. is a biotechnology company founded in 2017 and headquartered in Berkeley, California. The company focuses on developing genetically tractable strains from non-model micro-species, specializing in the domestication and genetic engineering of bacteria that are typically resistant to industrial applications. By utilizing a unique technology platform, MicroByre creates a reliable and generalizable domestication pipeline that supports fermentation processes. Its machine-learning platform analyzes a comprehensive dataset to identify bacteria that meet specific industrial functional criteria, facilitating precise genetic modifications. This approach provides clients with enhanced flexibility and yield while reducing the need for nutritional additives and improving contamination tolerance and phage resistance. Overall, MicroByre serves the biotechnology sector by addressing challenges in microbial utilization for industrial purposes.
Via Separations, Inc. is a company based in Somerville, Massachusetts, focused on developing membrane-based products for the efficient separation of industrial liquids in complex environments. Incorporated in 2016, the company utilizes advanced materials technology that significantly reduces energy consumption—reportedly using ten times less energy than traditional separation methods. Via Separations specializes in industrial decarbonization through its innovative membrane filtration systems, improving selectivity between nano filtration solutes while enhancing temperature stability, solvent resistance, and oxidizer tolerance. This enables manufacturing facilities to increase productivity while minimizing their energy usage.
Verve Motion specializes in the development of lightweight wearable exo-suits aimed at enhancing the safety and comfort of workers engaged in physically demanding tasks. By integrating robotics, apparel design, and movement science, the company creates innovative textile-based solutions that adapt to the movements of the wearer. These exo-suits provide support by delivering force at critical moments while remaining nonrestrictive, thereby promoting a safer work environment. Additionally, Verve Motion's designs contribute to a more restful experience for workers during their off-hours.
Ubiquitous Energy, Inc. is a Silicon Valley-based company that specializes in the development of transparent solar technology. Founded in 2011 and originally spun out from the Massachusetts Institute of Technology, the company has created ClearView Power technology, which allows for the selective conversion of ultraviolet and near-infrared light into electricity while permitting visible light to pass through. This innovative approach enables everyday surfaces, such as windows and smart glass, to function as solar panels without compromising their appearance. ClearView Power serves as an energy source for various electronic devices, including wearables, tablets, and digital signage, thereby addressing battery life limitations in mobile devices. Additionally, Ubiquitous Energy has established a strategic development agreement with Asahi Glass Co., Ltd. to further advance its technology in the market.
Clerio Vision is a medical device company that specializes in the fields of refractive, laser, ophthalmic, medical device, contact lenses, and intraocular lenses. The company is in process of developing and commercializing a portfolio of next-generation products in contact lenses. Clerio Vision was founded in 2014 and headquartered in Rochester, New York.
Swift Solar Inc. is a U.S.-based company specializing in the design and manufacture of lightweight, flexible solar panels. Founded in 2017 and headquartered in San Carlos, California, with an additional facility in Golden, Colorado, the company focuses on advanced photovoltaic technology utilizing perovskite semiconductors. Swift Solar's products are engineered for diverse applications, including aerospace, automotive, and building sectors. The team comprises experts from prestigious institutions such as Stanford, MIT, and the University of Washington, who leverage their knowledge to develop innovative solar cell architectures and specialized manufacturing techniques. Swift Solar's ultra-thin perovskite films are designed for high efficiency, enabling the production of tandem solar cells that maximize light absorption and conversion efficiency while maintaining a low weight.
Concerto Biosciences discovers and develops specific combinations of microbial ensembles. Using kChip, a patented, high-throughput platform that constructs and screens millions of defined microbial communities - Concerto creates massive data sets on how microbes function when growing in complex communities. From these data, Concerto directly discovers microbial ensembles that perform a desired task and learns design rules for ensemble engineering.
Boston Meats, Inc. produces alternative meat products using proteins. It also develops fiber production technology to produce meats using natural proteins. The company was founded in 2020 and is based in Somerville, Massachusetts.
Humanyze is a company that specializes in workplace solutions, focusing on improving organizational performance through people analytics. Founded in 2010 and headquartered in Boston, Massachusetts, with operations in Amsterdam, the Netherlands, Humanyze offers a platform called Wyze. This platform enables deployment administrators to configure essential company information, provides users with insightful dashboards, and facilitates benchmarking against external data sources. Additionally, Humanyze integrates with internal systems to generate insights across various teams, job roles, divisions, and departments. The company also utilizes wearable sensors and digital data to enhance its analytics capabilities. Humanyze's unique approach combines technology developed at the MIT Media Lab with small Bluetooth beacons, allowing users to gather and analyze data either for individual use or in an anonymized and aggregated manner for management purposes.
Boston Meats, Inc. produces alternative meat products using proteins. It also develops fiber production technology to produce meats using natural proteins. The company was founded in 2020 and is based in Somerville, Massachusetts.
Agility Robotics Inc. is a robotics development company founded in 2015 and based in Albany, Oregon. It specializes in designing and developing bipedal robots, notably Cassie, which is capable of walking and running. The company leverages its expertise in legged locomotion, rooted in extensive academic research, to create robots that serve as mobile sensor platforms and can operate in real-world environments. Agility Robotics aims to produce efficient, agile, and robust mobility solutions that can work alongside humans in various settings, such as offices, factories, and homes. Its technology enables clients to automate tasks in diverse terrains with minimal programming, addressing the practical needs of academic, corporate, and military sectors.
5x5 Technologies Inc is a manufacturer of unmanned aircraft systems, specializing in the development of advanced technology solutions that enhance the efficiency of unmanned aerial vehicles (UAVs). Founded in 2016 and based in St. Petersburg, Florida, the company focuses on 3D spatial computing and artificial intelligence to transform data collected by drones into highly detailed digital models. Its Ávrio engineering platform is designed for asset management, inspection, and analysis, enabling organizations in sectors such as telecommunications, energy, transportation, and government to optimize operations and achieve cost savings. By utilizing sophisticated analytics and machine learning, 5x5 Technologies helps clients automate workflows and unlock new revenue opportunities through better management of their assets.
Radical Plastics, Inc., based in Winchester, Massachusetts, develops biodegradable plastic compounds designed to address plastic pollution. Incorporated in 2018, the company utilizes a proprietary, naturally occurring catalyst to blend with conventional plastics, making them fully biodegradable in the natural environment. Their innovative technology offers soil degradable compounds specifically for agricultural film, providing an economically viable solution for brands seeking drop-in replacements for traditional plastics. Through its commitment to sustainability, Radical Plastics aims to contribute to reducing plastic waste and promoting environmental health.
Cogito Corporation is a Boston-based company that specializes in behavioral analytics software utilizing artificial intelligence technology to enhance human interactions. Its primary offering is a suite of solutions designed to analyze voice conversations in real time, providing professionals in sales, service, and care management with insights into emotional intelligence. This enables them to improve sales outcomes, customer experiences, and quality of care. Key products include Cogito Dialog, which delivers in-call analysis of customer interactions; Cogito Central, which continuously scores customer engagements for signs of distress; and Cogito Companion, a mobile application that alerts healthcare providers to behavioral changes indicating potential mental health risks. By leveraging validated behavioral science through AI and machine learning, Cogito's solutions aim to boost productivity and improve service delivery, fostering better relationships between professionals and their customers. The company, originally known as Cogito Health Inc., was founded in 2007.
RightHand Robotics, Inc. specializes in manufacturing robotic order-picking systems designed for various industrial applications, including e-commerce, food handling, and flexible manufacturing. The company offers innovative products such as the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that enhances the robots' ability to grasp items gently and make adjustments to avoid errors. Their technology allows robots to automatically grasp a wide range of items from bins and cases, eliminating the need for extensive data-entry or parameter-tuning, thereby making the systems cost-effective and adaptable to the evolving needs of businesses. Founded in 2015, RightHand Robotics is headquartered in Cambridge, Massachusetts, with a sales and business development office located in Frankfurt, Germany.
Quaise is an energy company pioneering millimeter wave drilling technology to access deep geothermal energy. Quaise is developing and commercializing novel millimeter wave drilling systems to harness geothermal energy around the globe, overcoming the geographic constraints limiting this energy source today.
Developer of a light-activated biomaterial platform designed to bring innovation in ocular and regenerative therapies. The company's platform focuses on bio-adhesion, tissue regeneration, tunable mechanics, and therapeutic loading across modalities from small molecules to cell and gene therapies through its photo crosslinked hydrogels, providing medical professionals to perform cell-based therapies for vision restoration, intraocular sustained release of small molecules and peptides, and in situ forming bioadhesives.
Commonwealth Fusion Systems LLC is a research company focused on developing fusion energy as a sustainable solution to combat climate change. Established in 2017 and based in Cambridge, Massachusetts, the company utilizes advanced rare-earth barium copper oxide superconductor technology to create energy through fusion. Commonwealth Fusion Systems combines decades of government-funded fusion research with innovative superconducting magnet technology to expedite the commercialization of fusion energy. The company emerged from the Massachusetts Institute of Technology and collaborates closely with MIT’s Plasma Science and Fusion Center, leveraging extensive research to enhance its development efforts. By designing and building fusion machines, Commonwealth Fusion aims to provide limitless and clean energy, contributing to the global transition toward sustainable energy sources.
Nelumbo Inc. manufactures thin superomniphobic nanocoating for air conditioning cooling coil fins and refrigerators. The company manufactures products, such as Ice-Nein and Omniphobe. Ice-Nein coating attacks frost build up to improve cooling coils for refrigeration equipment and reduces equipment defrosting downtime; and Omniphobe coating improves cooling coils for air conditioning equipment. The company caters to the heating and cooling industry. Nelumbo Inc. was founded in 2015 and is based in Menlo Park, California.
Kebotix, Inc. is a company focused on revolutionizing the materials discovery and production process through the integration of artificial intelligence, machine learning, and robotics. Founded in 2017 and headquartered in Cambridge, Massachusetts, Kebotix has developed a platform that significantly reduces the research cycle for discovering new chemicals and materials from years to mere months. This platform combines advanced AI decision-making with robotic automation, facilitating the efficient creation of innovative materials that enhance public health and promote sustainability. In addition to its core offerings, Kebotix provides partners with access to its digital research and development solutions, enabling the advancement of green chemistry and the reduction of hazardous substances in production processes.
EagleDream Technologies is a veteran-owned IT consulting firm established in 2013, specializing in cloud computing solutions. The company leverages its extensive experience and strong relationships in the information technology sector to address various business challenges through innovative strategies. EagleDream offers a wide range of services, including cloud adoption strategy, data modernization, disaster recovery, cloud hosting, application development, and data analytics. Additionally, the firm emphasizes the integration of artificial intelligence and machine learning to help businesses optimize their operations and harness the full potential of cloud-native technologies. Committed to prioritizing customer service, EagleDream believes that exceptional service is key to delivering quality work and achieving client success.
Honeoye Remedies specializes in all-natural skincare products designed for cosmetic use, emphasizing safety and efficacy through the use of high-quality ingredients that undergo laboratory testing. The brand focuses on creating products free from harsh chemicals, perfumes, and artificial dyes, leveraging the natural antibiotic properties of honey and tea tree oil. This approach enables the development of skincare solutions that promote wound healing and effectively address various skin irritations, including rashes, scrapes, and dry skin. By prioritizing natural ingredients, Honeoye Remedies aims to provide consumers with safe alternatives for their skincare needs.
Verve Motion specializes in the development of lightweight wearable exo-suits aimed at enhancing the safety and comfort of workers engaged in physically demanding tasks. By integrating robotics, apparel design, and movement science, the company creates innovative textile-based solutions that adapt to the movements of the wearer. These exo-suits provide support by delivering force at critical moments while remaining nonrestrictive, thereby promoting a safer work environment. Additionally, Verve Motion's designs contribute to a more restful experience for workers during their off-hours.
Operator of an ophthalmology biopharmaceutical company intended to revolutionize the standard of care in ocular surface disease. The company offers eye disease-modifying therapy for dry eyes, enabling patients to get therapy for their eye treatment.
Health Care Originals Inc., founded in 2014 and based in Rochester, New York, specializes in developing innovative solutions for managing chronic respiratory diseases, particularly asthma. The company's flagship product, ADAMM, encompasses a three-part system that includes a wearable device, a smartphone application, and a web portal. This comprehensive solution aids users in identifying and monitoring precursor symptoms of asthma attacks, thereby promoting better asthma management and overall respiratory health.
Clerio Vision is a medical device company that specializes in the fields of refractive, laser, ophthalmic, medical device, contact lenses, and intraocular lenses. The company is in process of developing and commercializing a portfolio of next-generation products in contact lenses. Clerio Vision was founded in 2014 and headquartered in Rochester, New York.
C2Sense, Inc. specializes in the development of chemiresistive gas sensors aimed at applications in food and agriculture. The company’s sensors detect gases such as ethylene and biogenic amines at very low concentrations, facilitating the monitoring of fruit ripeness and the freshness of meat, fish, and poultry throughout the supply chain. By providing accurate data, C2Sense enables growers, shippers, distributors, retailers, and consumers to make informed decisions that help reduce food waste. Founded in 2013 as a spinout from MIT, C2Sense employs nanotechnology and advanced chemical engineering techniques to create miniaturized mobile sensing solutions. In addition to food-related applications, the company’s technology addresses challenges in rapid medical diagnostics, product authentication, environmental monitoring, and safety across various sectors. Based in Cambridge, Massachusetts, C2Sense is committed to promoting a healthier and safer world through its innovative sensing technology.
Xibus Systems, Inc. is a biotechnology company based in Somerville, Massachusetts, specializing in the development of microbiological analytics and testing tools. The company focuses on creating solutions that detect pathogens, allergens, and spoilage organisms in consumable products. By integrating materials science, biotechnology, and optics, Xibus Systems aims to provide quantitative and array-based testing capabilities that are both efficient and cost-effective. Their innovative technology is designed for high throughput and rapid results, while also featuring a roadmap for compact and handheld hardware options. This unique combination of proprietary materials and biological agents positions Xibus Systems to effectively address the growing demands for food safety and quality assurance in the market.
Lucy Therapeutics is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative treatments for neurological diseases that originate in the mitochondria. Founded in 2017, the company employs a unique drug discovery approach that targets early disease pathogenesis, aiming to modify disease progression rather than merely alleviate symptoms. Their primary focus is on Rett Syndrome, a severe pediatric condition for which no effective drug treatments currently exist. In addition to Rett Syndrome, Lucy Therapeutics plans to expand its research to address other neurologically focused diseases, including Parkinson's and Alzheimer's diseases. The company also develops proprietary small molecule therapies and diagnostic biomarkers for the central nervous system, utilizing genetic technologies to provide insights into personalized medicine and enhance patient outcomes.
Gradiant Energy Services, Inc. is an oilfield services company specializing in water treatment solutions for the oil and gas industry, particularly in the Permian and Marcellus shale regions. Founded in 2012 and headquartered in Denver, Colorado, with a regional office in Midland, Texas, the company offers various services, including bacteria treatment, re-usable clean brine, evaporative disposal, and freshwater/desalination. Gradiant Energy Services focuses on helping exploration and production operators manage the treatment, reuse, and recycling of flowback and produced water. The company aims to provide safe, reliable, and cost-effective solutions that address the growing challenges associated with water usage and wastewater management in oil extraction processes.
Swift Solar Inc. is a U.S.-based company specializing in the design and manufacture of lightweight, flexible solar panels. Founded in 2017 and headquartered in San Carlos, California, with an additional facility in Golden, Colorado, the company focuses on advanced photovoltaic technology utilizing perovskite semiconductors. Swift Solar's products are engineered for diverse applications, including aerospace, automotive, and building sectors. The team comprises experts from prestigious institutions such as Stanford, MIT, and the University of Washington, who leverage their knowledge to develop innovative solar cell architectures and specialized manufacturing techniques. Swift Solar's ultra-thin perovskite films are designed for high efficiency, enabling the production of tandem solar cells that maximize light absorption and conversion efficiency while maintaining a low weight.
Kebotix, Inc. is a company focused on revolutionizing the materials discovery and production process through the integration of artificial intelligence, machine learning, and robotics. Founded in 2017 and headquartered in Cambridge, Massachusetts, Kebotix has developed a platform that significantly reduces the research cycle for discovering new chemicals and materials from years to mere months. This platform combines advanced AI decision-making with robotic automation, facilitating the efficient creation of innovative materials that enhance public health and promote sustainability. In addition to its core offerings, Kebotix provides partners with access to its digital research and development solutions, enabling the advancement of green chemistry and the reduction of hazardous substances in production processes.
Liquid X is a company specializing in the development of innovative metallic inks that enable the printing of functional components for various electronic devices. Their inks, which contain actual metal atoms rather than nanoparticles or metal flakes, offer superior properties such as high conductivity, thin and precise features, and excellent adhesion. This unique formulation allows for low-temperature processing and short production times, making it possible to use a wide range of substrates, including paper, gauze, and flexible plastics. Liquid X collaborates with manufacturers in the electronics industry to create applications such as sensors, heating elements, and smart textiles. The versatility of their inks supports various deposition methods, including inkjet, flexography, and gravure, positioning Liquid X as a key player in the emerging market for advanced electronic materials.