Safeguard Scientifics

Safeguard Scientifics, founded in 1953 and based in Radnor, Pennsylvania, is a private equity and venture capital firm that specializes in providing growth capital to technology companies, particularly in the healthcare, financial services, and digital media sectors. The firm focuses on expansion financings, management buyouts, and early to growth-stage investments, typically ranging from $5 million to $25 million. Safeguard seeks opportunities in companies that possess proprietary technology and intellectual property, preferring to be a significant shareholder, often holding between 20 percent and 50 percent of ownership. The firm primarily invests across the United States, with a concentration in the Mid-Atlantic region and Southeastern Canada. Its portfolio includes investments in areas such as software as a service, artificial intelligence, molecular diagnostics, and digital health, reflecting a commitment to fostering innovation and supporting entrepreneurs in building sustainable market leaders.

Caleb Bank

Senior Venture Capital Associate

Alex A. Fuiks

Associate

Steven J. Grenfell

Senior Vice President and Managing Director, Operations

Mark A. Herndon

Senior Vice President and Chief Financial Officer

Gary J. Kurtzman

Senior Vice President and Managing Director, Healthcare

Mark Mitchell

Vice President and Managing Director

Russell E. Palmer

Former Director

Robert J. Rosenthal

Chairman of the Board

Eric C. Salzman

CEO

Heinz C. Schimmelbusch

Former Director

John E. Shave

Senior Vice President, Investor Relations and Corporate Communications

Brian Sisko

President and Chief Executive Officer

Seth Zuckerman

Senior Associate, Healthcare

128 past transactions

Moxe Health

Series B in 2022
Moxe Health streamlines the bi-directional exchange of clinical data between health plans and provider systems. The company provide solutions for risk adjustment, HEDIS and Star ratings, claims denial management, HCC reconciliation, patient summary, ADT notifications, and care gap management. Plans seamlessly send back data and insights while never straying from clinicians’ EHR workflows. Moxe’s clinical data clearinghouse allows health plans to easily receive information from health systems. Health plans can then seamlessly send back data and insights. With automated solutions for risk adjustment, quality, and care management programs, Moxe facilitates access to the information essential to your success in the market shift to value-based care. Moxe’s neutrality in providing data connectivity lets you realize the full potential of your existing investments in population health, quality, and analytics solutions.

Moxe Health

Venture Round in 2021
Moxe Health streamlines the bi-directional exchange of clinical data between health plans and provider systems. The company provide solutions for risk adjustment, HEDIS and Star ratings, claims denial management, HCC reconciliation, patient summary, ADT notifications, and care gap management. Plans seamlessly send back data and insights while never straying from clinicians’ EHR workflows. Moxe’s clinical data clearinghouse allows health plans to easily receive information from health systems. Health plans can then seamlessly send back data and insights. With automated solutions for risk adjustment, quality, and care management programs, Moxe facilitates access to the information essential to your success in the market shift to value-based care. Moxe’s neutrality in providing data connectivity lets you realize the full potential of your existing investments in population health, quality, and analytics solutions.

Syapse

Series F in 2020
Syapse, Inc. is a company that specializes in precision medicine through its software platform, which integrates and analyzes clinical, molecular, treatment, and outcomes data. This platform supports data-driven decision-making for healthcare executives, care teams, and researchers involved in precision medicine programs. One of its key offerings is the Syapse Learning Health Network, a global data-sharing network focused on oncology, which leverages real-world data to enhance clinical decision-making. By connecting health systems, life sciences companies, and regulators, Syapse aims to accelerate the generation of real-world evidence to improve cancer patient outcomes. Founded in 2008 and headquartered in San Francisco, California, Syapse is committed to ensuring that all cancer patients receive high-quality care through improved precision medicine initiatives.

Trice Medical

Series C in 2019
Trice Medical, Inc. specializes in developing advanced orthopedic diagnostic devices that incorporate camera-enabled and needle-based technologies. The company's products facilitate micro-invasive procedures, allowing for effective visualization and treatment in an office setting, which enhances patient comfort and reduces the need for traditional surgical interventions. By providing instant diagnostic results, Trice Medical aims to improve patient care while minimizing costs for physicians and payors. The company was established in 2011 and is headquartered in Malvern, Pennsylvania.

InfoBionic

Venture Round in 2018
InfoBionic, Inc. is a healthcare technology company based in Massachusetts, founded in 2011. It specializes in remote patient monitoring through its MoMe™ platform, which is a cloud-based service designed to enhance the efficiency of cardiac diagnostic services. The MoMe System focuses on cardiac arrhythmia detection, allowing healthcare providers to monitor patients' heart health continuously by streaming electrocardiogram, respiration, and motion data to the cloud for real-time analysis. This technology aims to improve clinical efficiency and patient care by providing physicians with anytime, anywhere access to critical patient data, ultimately facilitating better detection and treatment of cardiac complications.

Zipnosis

Series B in 2018
Zipnosis, Inc. operates a virtual healthcare platform that connects patients with clinicians through phone and video interviews. The company specializes in online diagnosis, triage, and telehealth, providing device-agnostic virtual care that enhances patient choice and convenience while improving efficiency for healthcare providers. In addition to virtual consultations, Zipnosis offers a ZipTicket, which serves as a healthcare boarding pass, granting patients access to clinics for in-person assessments or lab tests. Founded in 2008 and headquartered in Minneapolis, Minnesota, Zipnosis collaborates with strategic partners to advance its mission of delivering accessible and efficient healthcare solutions.

meQuilibrium

Series C in 2018
meQuilibrium offers individuals and employees with online stress management solutions and measurements. It is the only clinically validated resilience platform leveraging behavioral psychology, neuroscience, and analytics to deliver transformative insights that change lives and businesses. meQuilibrium was founded in 2010 and is headquartered in Boston, Massachusetts.

Propeller Health

Series D in 2018
Propeller Health is a mobile platform that offers sensors, mobile apps, analytics, and services to support respiratory health management. The HIPAA compliant platform stores users’ data in a cloud computing infrastructure. The Propeller sensor and mobile application help users learn more about and better manage their asthma, COPD, and respiratory disease. The Propeller sensor attaches to users’ inhalers and wirelessly syncs with their smartphones. It tracks their triggers and symptoms and sends personalized feedback and education to their phones based on the symptoms. Users can see how often they use the medication, and set up medication reminders and alerts. Propeller community enables users to share their Propeller data with their physician and family members. Propeller Health is backed by Safeguard Scientifics, The Social+Capital Partnership, California HealthCare Foundation, and other investors. The platform works with organizations such as Dignity Health, Wyckoff Heights Medical Center, Amerigroup Florida, and the City of Louisville. The system has been featured in The Economist, Washington Post, Fast Company, Wired, and Scientific American. Propeller Health has received TEDMED Innovation Showcase, White House Champion of Change, and Bluetooth Breakthrough Product awards. Propeller Health was launched by David Van Sickle, Greg Tracy, and Mark Gehring and its operations are based in Wisconsin, United States.

Prognos

Series C in 2017
Prognos is a healthcare AI company dedicated to improving disease management through early intervention in collaboration with payers, life sciences, and diagnostics companies. It operates the Prognos Registry, which is the largest repository of clinical diagnostics information, encompassing over 5 billion medical records across more than 30 disease areas and covering 100 million patients. The company has developed 500 proprietary clinical algorithms that facilitate the early identification of patients, thereby enhancing treatment decision-making and risk management. Its platform, prognosFACTOR, efficiently analyzes vast amounts of lab and health records from over 325 million de-identified patients, providing rapid answers to clinically-focused healthcare inquiries. Prognos offers HIPAA-compliant healthcare data through its Prognos Marketplace, catering to various applications such as cohort design and health outcomes analysis, with a client base that includes a significant number of leading pharmaceutical manufacturers and payers.

Syapse

Series D in 2017
Syapse, Inc. is a company that specializes in precision medicine through its software platform, which integrates and analyzes clinical, molecular, treatment, and outcomes data. This platform supports data-driven decision-making for healthcare executives, care teams, and researchers involved in precision medicine programs. One of its key offerings is the Syapse Learning Health Network, a global data-sharing network focused on oncology, which leverages real-world data to enhance clinical decision-making. By connecting health systems, life sciences companies, and regulators, Syapse aims to accelerate the generation of real-world evidence to improve cancer patient outcomes. Founded in 2008 and headquartered in San Francisco, California, Syapse is committed to ensuring that all cancer patients receive high-quality care through improved precision medicine initiatives.

QuanticMind

Series B in 2017
QuanticMind Inc. develops a predictive advertising management software that focuses on optimizing paid search, social media, display, and mobile advertising. Founded in 2011 and based in Redwood City, California, the company has established itself as a pioneer in the field by utilizing advanced technologies such as machine learning, distributed cloud computing, and in-memory processing. QuanticMind's platform integrates cross-channel and third-party data to provide actionable insights for advertisers, enabling them to make informed decisions and maximize their advertising performance. Additionally, QuanticMind offers services including data quality assurance, technical support, and training to enhance user experience and effectiveness. The company serves a global community of data-driven marketers who rely on its innovative solutions to improve their advertising strategies.

Trice Medical

Series C in 2017
Trice Medical, Inc. specializes in developing advanced orthopedic diagnostic devices that incorporate camera-enabled and needle-based technologies. The company's products facilitate micro-invasive procedures, allowing for effective visualization and treatment in an office setting, which enhances patient comfort and reduces the need for traditional surgical interventions. By providing instant diagnostic results, Trice Medical aims to improve patient care while minimizing costs for physicians and payors. The company was established in 2011 and is headquartered in Malvern, Pennsylvania.

T-REX

Series B in 2017
Enterprise Fintech Platform: T-REX’s mission is to make complex capital markets more liquid through enhanced transparency and efficiency. In order to facilitate growth in complex asset classes, T-REX aims to continuously build effective market-relevant financial infrastructure that allows complex markets to be more robust through unprecedented transparency. T-REX is the financial and risk analytics platform for complex asset classes: increasing standardization, efficiency, and transparency. Through its enterprise SaaS platform, T-REX unlocks hundreds of billions of dollars currently seeking investment through modules that combine analysis across assets, loans, bonds, and other capital structures. Before T-REX, the value of the assets was opaque, non-standard, and manually evaluated one asset at a time. With T-REX, industry participants can now efficiently invest in, securitize, and manage portfolios of assets with complete transparency.

CloudMine

Series A in 2017
Rethink how you develop mobile applications. Significantly reduce your time to deployment, total cost, and overall ease of mind when it comes to developing mobile applications, integrating disparate datasets and maintaining IT infrastructures. CloudMine is a Managed Mobility solution that: 1) Eliminates the need for ongoing maintenance and management of mobile applications. 2) Accelerates app development by 70% through mobile-optimized infrastructure and a suite of prefabricated web services. 3) Standardizes your mobility platform to provide IT-approved common tooling across all business units.

VitalTrax

Seed Round in 2017
VitalTrax connects patients with clinical trials with its cloud-based clinical trial network. VitalTrax offers Wing, a solution that simplifies clinical trials enrollment. Wing is a clinical trial network that provides innovative ways for people to easily seek optional treatments for themselves or people that they love and play an important role in helping develop new ways to fight diseases.

Velano Vascular

Series B in 2017
Velano Vascular's technologies transform care by reducing the stress and anxiety related to blood draws during hospitalization. The company's needle-free device reduces pain and discomfort for patients, and enhances safety and efficiency for providers. Founded by a patient and a physician, Velano Vascular is backed by First Round Capital, Kapor Capital and White Owl Capital. The company’s collaborators include leading U.S. hospital systems and organizations innovating in patient-centered care.
Cognitive Operational Systems, LLC, based in Philadelphia, Pennsylvania, specializes in developing inventory management solutions for the retail sector through the use of robotics, artificial intelligence, and computer vision. Founded in 2012, the company’s technology enables robots to efficiently navigate retail environments, managing inventory, ensuring compliance with planograms and promotions, and providing indoor localization and navigation. Additionally, it offers mapping capabilities that detail store layouts and architecture. By leveraging university research, Cognitive Operational Systems aims to bridge the gap between academic advancements and practical applications in the fields of artificial intelligence and machine perception.

T-REX

Grant in 2016
Enterprise Fintech Platform: T-REX’s mission is to make complex capital markets more liquid through enhanced transparency and efficiency. In order to facilitate growth in complex asset classes, T-REX aims to continuously build effective market-relevant financial infrastructure that allows complex markets to be more robust through unprecedented transparency. T-REX is the financial and risk analytics platform for complex asset classes: increasing standardization, efficiency, and transparency. Through its enterprise SaaS platform, T-REX unlocks hundreds of billions of dollars currently seeking investment through modules that combine analysis across assets, loans, bonds, and other capital structures. Before T-REX, the value of the assets was opaque, non-standard, and manually evaluated one asset at a time. With T-REX, industry participants can now efficiently invest in, securitize, and manage portfolios of assets with complete transparency.

Spongecell

Venture Round in 2016
Spongecell, Inc. designs, develops, and offers advertising technology tools and services. It transforms banner advertising into flash advertising with interactive features, such as video, interactive mapping, carousels, social media, and more. The company also provides interactive display space for consumer interaction and delivering brand engagement. It serves creatives, media, and brand advertisers. Spongecell, Inc. was founded in 2006 and is based in New York, New York. As of January 29, 2018, Spongecell, Inc. operates as a subsidiary of Simplicity Marketing Ltd.

Brickwork

Series A in 2016
Brickwork powers the new Pre-Visit Experience for customers of the world’s leading brands and retailers. Brickwork’s SaaS platform delivers a better pre-visit experience: providing their customers more accurate store information, more access to events and promotions, more personal assistance when they arrive in-store, and more confidence that products are available near them. Brickwork opens a new world of actionable data for marketers and store teams, starting with its unique measure of Digital-to-Store Conversion, to drive traffic, engagement, conversion, and basket size. It was founded in 2013 and is headquartered in New York, New York.

Propeller Health

Series C in 2016
Propeller Health is a mobile platform that offers sensors, mobile apps, analytics, and services to support respiratory health management. The HIPAA compliant platform stores users’ data in a cloud computing infrastructure. The Propeller sensor and mobile application help users learn more about and better manage their asthma, COPD, and respiratory disease. The Propeller sensor attaches to users’ inhalers and wirelessly syncs with their smartphones. It tracks their triggers and symptoms and sends personalized feedback and education to their phones based on the symptoms. Users can see how often they use the medication, and set up medication reminders and alerts. Propeller community enables users to share their Propeller data with their physician and family members. Propeller Health is backed by Safeguard Scientifics, The Social+Capital Partnership, California HealthCare Foundation, and other investors. The platform works with organizations such as Dignity Health, Wyckoff Heights Medical Center, Amerigroup Florida, and the City of Louisville. The system has been featured in The Economist, Washington Post, Fast Company, Wired, and Scientific American. Propeller Health has received TEDMED Innovation Showcase, White House Champion of Change, and Bluetooth Breakthrough Product awards. Propeller Health was launched by David Van Sickle, Greg Tracy, and Mark Gehring and its operations are based in Wisconsin, United States.

Moxe Health

Series A in 2016
Moxe Health streamlines the bi-directional exchange of clinical data between health plans and provider systems. The company provide solutions for risk adjustment, HEDIS and Star ratings, claims denial management, HCC reconciliation, patient summary, ADT notifications, and care gap management. Plans seamlessly send back data and insights while never straying from clinicians’ EHR workflows. Moxe’s clinical data clearinghouse allows health plans to easily receive information from health systems. Health plans can then seamlessly send back data and insights. With automated solutions for risk adjustment, quality, and care management programs, Moxe facilitates access to the information essential to your success in the market shift to value-based care. Moxe’s neutrality in providing data connectivity lets you realize the full potential of your existing investments in population health, quality, and analytics solutions.

Medcrypt

Seed Round in 2016
MedCrypt is a cybersecurity company focused on protecting medical devices by providing data security as a service to medical device original equipment manufacturers (OEMs). Founded in 2016 and based in Encinitas, California, MedCrypt's platform incorporates essential security features that ensure medical devices, such as pacemakers and surgical robots, operate only on instructions from trusted sources. The company's solutions include user authentication, data encryption, and transaction monitoring, which help hospitals and health systems prevent unauthorized access and misuse of medical devices. By enabling engineers to integrate these security measures swiftly and efficiently, MedCrypt allows them to concentrate on developing innovative clinical features that can enhance patient care.

InfoBionic

Series B in 2016
InfoBionic, Inc. is a healthcare technology company based in Massachusetts, founded in 2011. It specializes in remote patient monitoring through its MoMe™ platform, which is a cloud-based service designed to enhance the efficiency of cardiac diagnostic services. The MoMe System focuses on cardiac arrhythmia detection, allowing healthcare providers to monitor patients' heart health continuously by streaming electrocardiogram, respiration, and motion data to the cloud for real-time analysis. This technology aims to improve clinical efficiency and patient care by providing physicians with anytime, anywhere access to critical patient data, ultimately facilitating better detection and treatment of cardiac complications.

Aktana

Series B in 2016
Aktana helps life science companies get the most out of artificial intelligence for commercializing their products. Its platform harnesses machine learning algorithms to enable marketing and sales teams to optimize their engagement with prescribing physicians. Aktana supports more than 100 brands and more than half the top 20 pharmaceutical companies worldwide to increase revenue, capitalize on data investments, and drive channel productivity and results. The company’s focus on the life sciences market allows Aktana to understand and incorporate unique market dynamics more deeply than the major AI players. Headquartered in San Francisco, Aktana also has offices in New York, Philadelphia, London, Barcelona, Tokyo, Osaka, and Shanghai.

Noble.MD

Seed Round in 2016
Noble.MD is a healthcare technology company based in Bryn Mawr, Pennsylvania, founded in 2012. The company has developed Theo, a digital healthcare advisory platform designed to assist patients in identifying health and behavioral risks. It engages patients in managing these risks through targeted programs and interventions. The platform captures essential patient data at the point of care, facilitating value-based reimbursement and streamlining the alignment of provider and payer interests. By focusing on real-time patient engagement and data collection, Noble.MD aims to enhance risk identification, coding, and management in modern healthcare settings.

Transactis

Series E in 2016
Transactis, Inc. offers Software-as-a-Service solutions for electronic bill presentment and payment, primarily within the United States. Its flagship product, BillerIQ, is a cloud-based platform that enables businesses to send electronic bills and invoices while facilitating online, phone, and mobile payments. Additionally, the company provides DocumentIQ, a digital document management solution that helps organizations manage and archive documents electronically. Transactis serves a diverse range of sectors, including financial services, healthcare, utilities, and real estate, among others. The company operates through a network of resellers, such as financial institutions and technology firms, offering a suite of sales, marketing, and operational support to enhance their service delivery. Founded in 2001 and headquartered in New York, Transactis adheres to stringent regulatory standards, ensuring compliance with industry requirements. Since its incorporation, it has evolved into a subsidiary of Mastercard Incorporated, reflecting its significant role in transforming traditional billing and payment processes into efficient digital alternatives.

Velano Vascular

Series A in 2016
Velano Vascular's technologies transform care by reducing the stress and anxiety related to blood draws during hospitalization. The company's needle-free device reduces pain and discomfort for patients, and enhances safety and efficiency for providers. Founded by a patient and a physician, Velano Vascular is backed by First Round Capital, Kapor Capital and White Owl Capital. The company’s collaborators include leading U.S. hospital systems and organizations innovating in patient-centered care.

Syapse

Series C in 2016
Syapse, Inc. is a company that specializes in precision medicine through its software platform, which integrates and analyzes clinical, molecular, treatment, and outcomes data. This platform supports data-driven decision-making for healthcare executives, care teams, and researchers involved in precision medicine programs. One of its key offerings is the Syapse Learning Health Network, a global data-sharing network focused on oncology, which leverages real-world data to enhance clinical decision-making. By connecting health systems, life sciences companies, and regulators, Syapse aims to accelerate the generation of real-world evidence to improve cancer patient outcomes. Founded in 2008 and headquartered in San Francisco, California, Syapse is committed to ensuring that all cancer patients receive high-quality care through improved precision medicine initiatives.

Zipnosis

Series A in 2016
Zipnosis, Inc. operates a virtual healthcare platform that connects patients with clinicians through phone and video interviews. The company specializes in online diagnosis, triage, and telehealth, providing device-agnostic virtual care that enhances patient choice and convenience while improving efficiency for healthcare providers. In addition to virtual consultations, Zipnosis offers a ZipTicket, which serves as a healthcare boarding pass, granting patients access to clinics for in-person assessments or lab tests. Founded in 2008 and headquartered in Minneapolis, Minnesota, Zipnosis collaborates with strategic partners to advance its mission of delivering accessible and efficient healthcare solutions.

Cask

Series B in 2015
Cask Data, Inc. is a technology company that addresses big data challenges by providing an open-source application development platform tailored for the Hadoop ecosystem. This platform facilitates data and application virtualization, significantly accelerating the development process for a variety of real-time and batch use cases. Cask offers several key products, including Cask Coopr, a template-based cluster management solution for provisioning and scaling clusters in cloud environments, and Tigon, a distributed framework designed for real-time data processing and analytics. The company also provides a cloud sandbox for its application platform on Amazon Web Services. Founded in 2011 and based in Palo Alto, California, Cask Data was known as Continuuity, Inc. until its name change in 2014. It operates as a subsidiary of Alphabet Inc. and has formed strategic collaborations, including one with Cloudera.

QuanticMind

Series A in 2015
QuanticMind Inc. develops a predictive advertising management software that focuses on optimizing paid search, social media, display, and mobile advertising. Founded in 2011 and based in Redwood City, California, the company has established itself as a pioneer in the field by utilizing advanced technologies such as machine learning, distributed cloud computing, and in-memory processing. QuanticMind's platform integrates cross-channel and third-party data to provide actionable insights for advertisers, enabling them to make informed decisions and maximize their advertising performance. Additionally, QuanticMind offers services including data quality assurance, technical support, and training to enhance user experience and effectiveness. The company serves a global community of data-driven marketers who rely on its innovative solutions to improve their advertising strategies.

Sonobi

Series A in 2015
Sonobi, Inc. is an advertising technology company based in Winter Park, Florida, founded in 2011. It offers a comprehensive platform that facilitates connections between clients and buyers across various advertising channels, including networks, demand-side platforms, and trading desks. The platform enables publishers to effectively market their advertising inventory while allowing advertisers to identify and source marketing opportunities. Additionally, Sonobi provides a Consent Management Platform that helps publishers maintain compliance with privacy regulations such as the General Data Protection Regulation. By leveraging user-centric technology and intelligent data, Sonobi aims to enhance advertising effectiveness and foster stronger connections between brands and consumers, ultimately driving better results for publishers, media agencies, and advertisers.

Apprenda

Series D in 2015
Apprenda is a developer of a cloud-based enterprise platform used to power the next generation of enterprise software development. The company creates and supports modern, enterprise-ready application platforms for both cloud-native and traditional application workloads. With more than a decade of deep, enterprise customer insights, it provides compatible solution offerings for both individuals and IT departments, removing friction from the software delivery process and transforming IT into an engine of growth. Apprenda was established in 2007 and is headquartered in Troy, New York.

Pneuron

Series B in 2015
Pneuron overcomes the time, cost, and complexity challenges associated with traditional enterprise development, deployment and integration approaches. Using Pneuron’s Distributed Platform, organizations can leverage existing systems and infrastructure to connect data, applications, processes, and analytics without the need of intermediary databases, associated data integration costs or system replacement. In a single non-invasive “fabric” Pneuron allows the enterprise to manage the entire business solution lifecycle from a single screen – including development, deployment, integration, resiliency, availability and performance - freeing the enterprise to focus on realizing business value. The result is unprecedented productivity, engagement of business expertise, and reduced cost of success, inspiring new waves of innovation.

Clutch

Series B in 2015
Clutch Holdings, LLC specializes in customer intelligence and engagement software solutions. The company offers a consumer management platform that integrates point-of-sale (POS) data, e-commerce information, and consumer activity across social and mobile channels. Their services encompass customer relationship management (CRM), channel synthesis, segmentation, loyalty programs, gift card solutions, customer scoring, and various marketing strategies, including email and direct mail campaigns. Clutch targets a diverse range of industries, including footwear, telecom, apparel, automotive, banking, healthcare, and hospitality. Founded in 2012 and headquartered in Ambler, Pennsylvania, Clutch aims to empower business-to-consumer brands by providing innovative, data-driven marketing tools to help them effectively connect with and motivate their customers.

meQuilibrium

Series B in 2015
meQuilibrium offers individuals and employees with online stress management solutions and measurements. It is the only clinically validated resilience platform leveraging behavioral psychology, neuroscience, and analytics to deliver transformative insights that change lives and businesses. meQuilibrium was founded in 2010 and is headquartered in Boston, Massachusetts.

CloudMine

Series A in 2015
Rethink how you develop mobile applications. Significantly reduce your time to deployment, total cost, and overall ease of mind when it comes to developing mobile applications, integrating disparate datasets and maintaining IT infrastructures. CloudMine is a Managed Mobility solution that: 1) Eliminates the need for ongoing maintenance and management of mobile applications. 2) Accelerates app development by 70% through mobile-optimized infrastructure and a suite of prefabricated web services. 3) Standardizes your mobility platform to provide IT-approved common tooling across all business units.

Aventura Software

Series C in 2015
Aventura intelligently orchestrates assets, people, and systems to deliver the right information at the right time based on location and credentials. It locates and re-assigns the closest online printer and uniquely manages print routing to make it easier to detect and fix printing failures. Aventura was formed in 2007 and headquartered in Denver, Colorado.

Velano Vascular

Series A in 2015
Velano Vascular's technologies transform care by reducing the stress and anxiety related to blood draws during hospitalization. The company's needle-free device reduces pain and discomfort for patients, and enhances safety and efficiency for providers. Founded by a patient and a physician, Velano Vascular is backed by First Round Capital, Kapor Capital and White Owl Capital. The company’s collaborators include leading U.S. hospital systems and organizations innovating in patient-centered care.

Trice Medical

Series B in 2015
Trice Medical, Inc. specializes in developing advanced orthopedic diagnostic devices that incorporate camera-enabled and needle-based technologies. The company's products facilitate micro-invasive procedures, allowing for effective visualization and treatment in an office setting, which enhances patient comfort and reduces the need for traditional surgical interventions. By providing instant diagnostic results, Trice Medical aims to improve patient care while minimizing costs for physicians and payors. The company was established in 2011 and is headquartered in Malvern, Pennsylvania.

Propeller Health

Series B in 2014
Propeller Health is a mobile platform that offers sensors, mobile apps, analytics, and services to support respiratory health management. The HIPAA compliant platform stores users’ data in a cloud computing infrastructure. The Propeller sensor and mobile application help users learn more about and better manage their asthma, COPD, and respiratory disease. The Propeller sensor attaches to users’ inhalers and wirelessly syncs with their smartphones. It tracks their triggers and symptoms and sends personalized feedback and education to their phones based on the symptoms. Users can see how often they use the medication, and set up medication reminders and alerts. Propeller community enables users to share their Propeller data with their physician and family members. Propeller Health is backed by Safeguard Scientifics, The Social+Capital Partnership, California HealthCare Foundation, and other investors. The platform works with organizations such as Dignity Health, Wyckoff Heights Medical Center, Amerigroup Florida, and the City of Louisville. The system has been featured in The Economist, Washington Post, Fast Company, Wired, and Scientific American. Propeller Health has received TEDMED Innovation Showcase, White House Champion of Change, and Bluetooth Breakthrough Product awards. Propeller Health was launched by David Van Sickle, Greg Tracy, and Mark Gehring and its operations are based in Wisconsin, United States.

Transactis

Series D in 2014
Transactis, Inc. offers Software-as-a-Service solutions for electronic bill presentment and payment, primarily within the United States. Its flagship product, BillerIQ, is a cloud-based platform that enables businesses to send electronic bills and invoices while facilitating online, phone, and mobile payments. Additionally, the company provides DocumentIQ, a digital document management solution that helps organizations manage and archive documents electronically. Transactis serves a diverse range of sectors, including financial services, healthcare, utilities, and real estate, among others. The company operates through a network of resellers, such as financial institutions and technology firms, offering a suite of sales, marketing, and operational support to enhance their service delivery. Founded in 2001 and headquartered in New York, Transactis adheres to stringent regulatory standards, ensuring compliance with industry requirements. Since its incorporation, it has evolved into a subsidiary of Mastercard Incorporated, reflecting its significant role in transforming traditional billing and payment processes into efficient digital alternatives.

WebLinc

Series A in 2014
WebLinc is the parent company for the ecommerce platform Workarea Commerce Cloud and Orderbot order management system.The Workarea Commerce Platform's modern, agile technologies empower companies running global, omnichannel commerce operations, and enable retailers to consistently out-pace the competition. Weblinc's two products, Workarea Commerce Platform and Orderbot OMS support a number of highly successful retail and B2B clients including URBN's BHLDN and Terrain brands, Sanrio, The Reformation, STAPLES Canada, Buzzfeed, Live Nation, Woodcraft Supplies, and The Bouqs.

Trice Medical

Series B in 2014
Trice Medical, Inc. specializes in developing advanced orthopedic diagnostic devices that incorporate camera-enabled and needle-based technologies. The company's products facilitate micro-invasive procedures, allowing for effective visualization and treatment in an office setting, which enhances patient comfort and reduces the need for traditional surgical interventions. By providing instant diagnostic results, Trice Medical aims to improve patient care while minimizing costs for physicians and payors. The company was established in 2011 and is headquartered in Malvern, Pennsylvania.

Syapse

Series B in 2014
Syapse, Inc. is a company that specializes in precision medicine through its software platform, which integrates and analyzes clinical, molecular, treatment, and outcomes data. This platform supports data-driven decision-making for healthcare executives, care teams, and researchers involved in precision medicine programs. One of its key offerings is the Syapse Learning Health Network, a global data-sharing network focused on oncology, which leverages real-world data to enhance clinical decision-making. By connecting health systems, life sciences companies, and regulators, Syapse aims to accelerate the generation of real-world evidence to improve cancer patient outcomes. Founded in 2008 and headquartered in San Francisco, California, Syapse is committed to ensuring that all cancer patients receive high-quality care through improved precision medicine initiatives.

Lumesis

Series B in 2014
Lumesis, Inc. operates as a Software-as-a-Service and cloud-based financial technology company that provides regulatory and data solutions for the municipal marketplace. It offers DIVER Analytics, a solution that provides clients with access to various datasets, as well as a suite of analytical and visualization tools that address the realities of the municipal marketplace, such as stale financials, fiscal uncertainty, and infrequent ratings. The company also offers DIVER Advisor, a solution that is used to support clients’ evolving regulatory needs that address time-of-trade disclosure, supervision, and suitability; DIVER Data Services, a solution that provides clients with access to data and custom datasets formatted and delivered to the platform; and DIVER Geo Score that represents the score of the economic health of a particular geographic area to assist users in understanding the overall economic health of a selected geographic area. It serves the U.S. banks, broker/dealers, asset managers, insurance companies, hedge funds, municipal index providers, credit analysts, portfolio managers, risk managers, legal and compliance professionals, financial advisors, and private wealth managers. Lumesis, Inc. was founded in 2010 and is based in Stamford, Connecticut.

MediaMath

Series C in 2014
MediaMath, Inc. is a provider of digital advertising media and data management technology solutions for advertisers globally. The company's TerminalOne platform facilitates the activation of data, automates execution, and optimizes advertising interactions across various addressable media. Additionally, MediaMath offers an Omnichannel programmatic marketing platform that enhances personalized customer engagement, accesses media at scale, and utilizes machine learning for measurement and optimization. Beyond technology, MediaMath provides professional services in programmatic strategy, analytics, technology support, and advertising operations, as well as training and certification programs in digital marketing. Founded in 2007, MediaMath is headquartered in New York City and operates additional offices in various locations, including California, Massachusetts, Illinois, Florida, North Carolina, the United Kingdom, Spain, Germany, Singapore, Japan, Brazil, Australia, and India.

Sotera Wireless

Venture Round in 2014
Sotera Wireless, Inc. is a medical device company dedicated to the development, marketing and sale of a new generation of comprehensive vital signs monitoring. Sotera’s mission is to improve patient safety by empowering clinicians to detect early signs of deterioration in virtually any care setting and enable early intervention and rapid response, all without limiting the patient’s freedom of movement.

InfoBionic

Series B in 2014
InfoBionic, Inc. is a healthcare technology company based in Massachusetts, founded in 2011. It specializes in remote patient monitoring through its MoMe™ platform, which is a cloud-based service designed to enhance the efficiency of cardiac diagnostic services. The MoMe System focuses on cardiac arrhythmia detection, allowing healthcare providers to monitor patients' heart health continuously by streaming electrocardiogram, respiration, and motion data to the cloud for real-time analysis. This technology aims to improve clinical efficiency and patient care by providing physicians with anytime, anywhere access to critical patient data, ultimately facilitating better detection and treatment of cardiac complications.

Hoopla

Series B in 2014
Hoopla Software, Inc. develops and offers visual communication platform that connects, engages, and motivates employees in an organization. Its platform provides sales performance optimization platform as a service which leverages data, game mechanics, and communication tools to cultivate a high performance culture and drive results for sales employees. The company's products include Hoopla TV and Hoopla Mobile. Hoopla Software, Inc. was incorporated in 2008 and is based in San Jose, California.

Apprenda

Series C in 2013
Apprenda is a developer of a cloud-based enterprise platform used to power the next generation of enterprise software development. The company creates and supports modern, enterprise-ready application platforms for both cloud-native and traditional application workloads. With more than a decade of deep, enterprise customer insights, it provides compatible solution offerings for both individuals and IT departments, removing friction from the software delivery process and transforming IT into an engine of growth. Apprenda was established in 2007 and is headquartered in Troy, New York.

Dabo Health

Series A in 2013
Dabo Health provides the healthcare community a free platform to view and track improvement in key performance metrics, to collaborate across hospitals and healthcare systems, and to identify and share evidence based best practices in order to save lives. In the era of Big Data, we enlighten individuals, organizations and industries and empower fundamental change at all levels. By combining human-powered insights with raw, objective data, we inform confident decisions and drive efficiencies. Ours is a system that rewards collaboration with innovative ideas that are integral to the progression of humanity. We call it “The Power of Collective Intelligence.” We channel this shared knowledge of passionate professionals to empower progress.

Clutch

Venture Round in 2013
Clutch Holdings, LLC specializes in customer intelligence and engagement software solutions. The company offers a consumer management platform that integrates point-of-sale (POS) data, e-commerce information, and consumer activity across social and mobile channels. Their services encompass customer relationship management (CRM), channel synthesis, segmentation, loyalty programs, gift card solutions, customer scoring, and various marketing strategies, including email and direct mail campaigns. Clutch targets a diverse range of industries, including footwear, telecom, apparel, automotive, banking, healthcare, and hospitality. Founded in 2012 and headquartered in Ambler, Pennsylvania, Clutch aims to empower business-to-consumer brands by providing innovative, data-driven marketing tools to help them effectively connect with and motivate their customers.

Quantia

Series B in 2013
QuantiaMD is a leading online community and collaboration platform for physicians, enabling 160,000 healthcare professionals to share real-life clinical experiences efficiently and rapidly. The platform fosters interaction among physicians, allowing them to learn from both experts and peers, which enhances their ability to adapt to changes in medical practice and apply the latest medical insights. By facilitating swift engagement and alignment among physicians, QuantiaMD supports healthcare organizations in achieving key objectives that contribute to improved quality of care. Designed specifically for the contemporary needs of healthcare professionals, QuantiaMD is user-friendly, secure, and accessible on mobile devices.

Prognos

Series B in 2013
Prognos is a healthcare AI company dedicated to improving disease management through early intervention in collaboration with payers, life sciences, and diagnostics companies. It operates the Prognos Registry, which is the largest repository of clinical diagnostics information, encompassing over 5 billion medical records across more than 30 disease areas and covering 100 million patients. The company has developed 500 proprietary clinical algorithms that facilitate the early identification of patients, thereby enhancing treatment decision-making and risk management. Its platform, prognosFACTOR, efficiently analyzes vast amounts of lab and health records from over 325 million de-identified patients, providing rapid answers to clinically-focused healthcare inquiries. Prognos offers HIPAA-compliant healthcare data through its Prognos Marketplace, catering to various applications such as cohort design and health outcomes analysis, with a client base that includes a significant number of leading pharmaceutical manufacturers and payers.

Pneuron

Series B in 2013
Pneuron overcomes the time, cost, and complexity challenges associated with traditional enterprise development, deployment and integration approaches. Using Pneuron’s Distributed Platform, organizations can leverage existing systems and infrastructure to connect data, applications, processes, and analytics without the need of intermediary databases, associated data integration costs or system replacement. In a single non-invasive “fabric” Pneuron allows the enterprise to manage the entire business solution lifecycle from a single screen – including development, deployment, integration, resiliency, availability and performance - freeing the enterprise to focus on realizing business value. The result is unprecedented productivity, engagement of business expertise, and reduced cost of success, inspiring new waves of innovation.

Sotera Wireless

Series D in 2013
Sotera Wireless, Inc. is a medical device company dedicated to the development, marketing and sale of a new generation of comprehensive vital signs monitoring. Sotera’s mission is to improve patient safety by empowering clinicians to detect early signs of deterioration in virtually any care setting and enable early intervention and rapid response, all without limiting the patient’s freedom of movement.

Crescendo Bioscience

Series D in 2013
Crescendo Bioscience, Inc. is a company that specializes in developing quantitative diagnostic tools aimed at assisting rheumatologists in the management of patients with autoimmune and inflammatory diseases. The firm offers a range of services, including diagnostic, prognostic, staging, therapy selection, and monitoring capabilities for healthcare providers. Founded in 2002 and headquartered in South San Francisco, California, Crescendo Bioscience focuses on delivering clinical insights that enhance patient care in the field of molecular diagnostics.

AppFirst

Series B in 2012
AppFirst’s is a patented technology that provides a solution for collecting every event across web-scale applications, regardless of the infrastructure type or programming language. With microsecond visibility into all the applications and supporting resources across their shared infrastructure, IT Operations can now deterministically get to the root cause, effectively footprint applications to determine exactly what resources that application requires, and proactively identify when their applications become wobbly. Those responsible for the infrastructure finally have a way to continuously understand the performance of every application running on the shared-resources they own.

Hoopla

Series A in 2012
Hoopla Software, Inc. develops and offers visual communication platform that connects, engages, and motivates employees in an organization. Its platform provides sales performance optimization platform as a service which leverages data, game mechanics, and communication tools to cultivate a high performance culture and drive results for sales employees. The company's products include Hoopla TV and Hoopla Mobile. Hoopla Software, Inc. was incorporated in 2008 and is based in San Jose, California.

Good Start Genetics

Series B in 2012
Good Start Genetics, Inc., founded in 2007 and based in Cambridge, Massachusetts, is a molecular diagnostics company specializing in genetic screening for inherited diseases. The company aims to transform reproductive medicine by offering clinically relevant information to physicians and patients regarding genetic disorders. Its flagship product, EmbryVu, is a preimplantation genetic screening test designed to enhance in vitro fertilization by identifying suitable embryos for implantation and pregnancy. Good Start Genetics employs advanced next-generation DNA sequencing (NGS) technology, alongside other established genetic screening methods, to provide a comprehensive suite of genetic carrier screening tests through its GoodStart Select program. The company emphasizes customer care and genetic counseling, ensuring that patients receive actionable insights into known and novel genetic mutations. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

Lumesis

Series A in 2012
Lumesis, Inc. operates as a Software-as-a-Service and cloud-based financial technology company that provides regulatory and data solutions for the municipal marketplace. It offers DIVER Analytics, a solution that provides clients with access to various datasets, as well as a suite of analytical and visualization tools that address the realities of the municipal marketplace, such as stale financials, fiscal uncertainty, and infrequent ratings. The company also offers DIVER Advisor, a solution that is used to support clients’ evolving regulatory needs that address time-of-trade disclosure, supervision, and suitability; DIVER Data Services, a solution that provides clients with access to data and custom datasets formatted and delivered to the platform; and DIVER Geo Score that represents the score of the economic health of a particular geographic area to assist users in understanding the overall economic health of a selected geographic area. It serves the U.S. banks, broker/dealers, asset managers, insurance companies, hedge funds, municipal index providers, credit analysts, portfolio managers, risk managers, legal and compliance professionals, financial advisors, and private wealth managers. Lumesis, Inc. was founded in 2010 and is based in Stamford, Connecticut.

Spongecell

Series B in 2012
Spongecell, Inc. designs, develops, and offers advertising technology tools and services. It transforms banner advertising into flash advertising with interactive features, such as video, interactive mapping, carousels, social media, and more. The company also provides interactive display space for consumer interaction and delivering brand engagement. It serves creatives, media, and brand advertisers. Spongecell, Inc. was founded in 2006 and is based in New York, New York. As of January 29, 2018, Spongecell, Inc. operates as a subsidiary of Simplicity Marketing Ltd.

DriveFactor

Series A in 2011
DriveFactor is a consolidated contractors company that offers a range of insurance telematics technology solutions. The DriveFactor platform is built on a dynamic, scalable architecture, accepting data from any input method and enabling easy sharing with business partners. The team has built its technology and apps for insurance, and applies its expertise to help clients customize telematics solutions to meet their short- and long-term needs. It was founded in 2010 and is based in Glen Allen, Virginia, USA.

Hoopla

Series A in 2011
Hoopla Software, Inc. develops and offers visual communication platform that connects, engages, and motivates employees in an organization. Its platform provides sales performance optimization platform as a service which leverages data, game mechanics, and communication tools to cultivate a high performance culture and drive results for sales employees. The company's products include Hoopla TV and Hoopla Mobile. Hoopla Software, Inc. was incorporated in 2008 and is based in San Jose, California.

Prognos

Series A in 2011
Prognos is a healthcare AI company dedicated to improving disease management through early intervention in collaboration with payers, life sciences, and diagnostics companies. It operates the Prognos Registry, which is the largest repository of clinical diagnostics information, encompassing over 5 billion medical records across more than 30 disease areas and covering 100 million patients. The company has developed 500 proprietary clinical algorithms that facilitate the early identification of patients, thereby enhancing treatment decision-making and risk management. Its platform, prognosFACTOR, efficiently analyzes vast amounts of lab and health records from over 325 million de-identified patients, providing rapid answers to clinically-focused healthcare inquiries. Prognos offers HIPAA-compliant healthcare data through its Prognos Marketplace, catering to various applications such as cohort design and health outcomes analysis, with a client base that includes a significant number of leading pharmaceutical manufacturers and payers.

Putney

Series C in 2011
Putney, Inc. is a pharmaceutical company based in Portland, Maine, specializing in the development and sale of generic prescription medications for pets. Founded in 2006, Putney focuses on creating high-quality, veterinary-approved products that address common health issues in companion animals. Their portfolio includes medications such as Enrofloxacin tablets for bacterial infections in dogs and cats, Cefpodoxime Proxetil tablets for skin infections in dogs, Mupirocin ointment for canine skin infections, Carprofen caplets for pain management in osteoarthritis, and Ketamine HCl for anesthetic use in cats. Additionally, the company offers some human-approved products, including Ampicillin sodium and Amoxicillin capsules. Putney markets its products through a network of distributors across the United States and operates as a subsidiary of Dechra Pharmaceuticals plc.

NovaSom

Series D in 2011
NovaSom, Inc. is a privately held diagnostic-service provider for home testing and evaluation of sleep-disordered breathing, which includes the diagnosis of obstructive sleep apnea (OSA). The company is a Medicare-approved Independent Diagnostic Testing Facility (IDTF) and is fully accredited as both an Ambulatory Care Sleep Diagnostic Center and as a Telehealth provider by The Joint Commission. The home testing system manufactured and distributed by NovaSom has FDA clearance for the diagnostic evaluation of OSA in adults. NovaSom has integrated their home sleep testing system into a cloud-based, collaborative patient management platform for physicians and payers. It is based in Glen Burnie, Maryland, the company was incorporated in 1992.

PixelOptics

Series D in 2011
PixelOptics was founded in 2005 as the world's first composite lens company. Their unique and proprietary approach to lens design combines sound lens design principles and well-known, proven lens materials to create entirely new categories of eyeglass lenses.

ThingWorx

Series B in 2011
ThingWorx radically transforms application development for the the connected world, allowing companies to achieve a step change in operational innovation and resource efficiency.

Good Start Genetics

Series A in 2010
Good Start Genetics, Inc., founded in 2007 and based in Cambridge, Massachusetts, is a molecular diagnostics company specializing in genetic screening for inherited diseases. The company aims to transform reproductive medicine by offering clinically relevant information to physicians and patients regarding genetic disorders. Its flagship product, EmbryVu, is a preimplantation genetic screening test designed to enhance in vitro fertilization by identifying suitable embryos for implantation and pregnancy. Good Start Genetics employs advanced next-generation DNA sequencing (NGS) technology, alongside other established genetic screening methods, to provide a comprehensive suite of genetic carrier screening tests through its GoodStart Select program. The company emphasizes customer care and genetic counseling, ensuring that patients receive actionable insights into known and novel genetic mutations. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

Swaptree Inc.

Series D in 2010
Swaptree is a website that allows users to trade books, CDs, DVDs and video games with other users for freeSwaptree.com provides a platform for trading among its customers. The Company offers a site where the user can freely swap new and used DVDs, CDs, video games, and books with other members. Swaptree.com conducts services in the United States.

Molecular Biometrics

Series B in 2010
Molecular Biometrics, Inc. is a metabolomics company based in Norwood, Massachusetts, focused on developing non-invasive methodologies for assessing biological functions in health and disease, as well as for drug discovery and development. Established in 2005, the company leverages innovative metabolomic technologies to create molecular gastronomy kits. Its applications span various fields, including reproductive health, neurodegenerative diseases such as Alzheimer's and Parkinson's, maternal-fetal medicine, pulmonary metabolism and edema, and lactate metabolism. By applying its proprietary technology, Molecular Biometrics aims to enhance the understanding and treatment of complex health issues.

Quinnova Pharmaceuticals

Series B in 2009
Quinnova Pharmaceuticals, Inc., a specialty pharmaceutical company, engages in the development and commercial sale of prescription drug products based on dermal drug delivery platforms. It offers HYDRO 40 foam, a dry skin treatment product; tersi foam, a leave-on foam indicated for the treatment of seborrheic dermatitis and tinea versicolor; rinnovi nail system, a prescription nail system that is designed to clean, treat, and protect diseased, damaged, brittle, and ingrown nails; and cleanse and treat, a pad delivery technology system for the treatment of acne. Quinnova Pharmaceuticals, Inc. was founded in 2003 and is based in Newtown, Pennsylvania.

MediaMath

Venture Round in 2009
MediaMath, Inc. is a provider of digital advertising media and data management technology solutions for advertisers globally. The company's TerminalOne platform facilitates the activation of data, automates execution, and optimizes advertising interactions across various addressable media. Additionally, MediaMath offers an Omnichannel programmatic marketing platform that enhances personalized customer engagement, accesses media at scale, and utilizes machine learning for measurement and optimization. Beyond technology, MediaMath provides professional services in programmatic strategy, analytics, technology support, and advertising operations, as well as training and certification programs in digital marketing. Founded in 2007, MediaMath is headquartered in New York City and operates additional offices in various locations, including California, Massachusetts, Illinois, Florida, North Carolina, the United Kingdom, Spain, Germany, Singapore, Japan, Brazil, Australia, and India.

Avid Radiopharmaceuticals

Series D in 2009
Avid develops molecular imaging agents to aid medical management of chronic human diseases. They are located in Philadelphia, PA. Their mission is to develop new molecular imaging agents capable of changing the medical management of significant, chronic human diseases by identifying the first stages of pathological change, potentially assisting in earlier diagnosis, and better management and development of new therapies.

Bridgevine

Venture Round in 2009
Bridgevine Inc. offers a software-as-a-service (SaaS) marketing automation solution designed to enhance digital commerce. Its platform enables users to effectively reach customers with tailored offers, optimizing product positioning and facilitating cross-selling across various devices, including mobile and desktop. The company's Audience Optimization tools help marketers engage consumers at different stages of their shopping journey, while the Mover Media Program utilizes proprietary audiences to enhance marketing efforts. Additionally, Bridgevine provides Acquily, a referral platform for customer acquisition, and a Digital Engagement and Customer Acquisition Suite that includes various commerce and social engagement applications. The firm also delivers professional services and proprietary distribution channels for industries such as telecommunications, energy, and retail. Founded in 2003 and based in Vero Beach, Florida, Bridgevine was previously known as Broadband National, Inc. and became a subsidiary of Updater, Inc. in December 2019.

Garnet Biotherapeutics

Series A in 2009
Garnet BioTherapeutics is a clinical stage, venture-backed cell therapy company focused on dermal-based regenerative therapy.

Tengion

Series C in 2008
Tengion is a clinical-stage biotechnology company focused on the development of neo-organs and neo-tissues derived from a patient's own cells. The company has successfully completed two Phase 2 clinical trials in the United States for its Neo-Bladder Augment, which aims to assist children with neurogenic bladder resulting from spina bifida and adults with similar conditions due to spinal cord injuries. An earlier academic study on a urinary Neo-Bladder Augment was published in The Lancet in April 2006, highlighting its potential benefits. Tengion also holds an effective investigational new drug application for its Neo-Urinary Conduit and anticipates initiating a Phase 1 clinical trial for bladder cancer patients requiring bladder removal.

Molecular Biometrics

Series A in 2008
Molecular Biometrics, Inc. is a metabolomics company based in Norwood, Massachusetts, focused on developing non-invasive methodologies for assessing biological functions in health and disease, as well as for drug discovery and development. Established in 2005, the company leverages innovative metabolomic technologies to create molecular gastronomy kits. Its applications span various fields, including reproductive health, neurodegenerative diseases such as Alzheimer's and Parkinson's, maternal-fetal medicine, pulmonary metabolism and edema, and lactate metabolism. By applying its proprietary technology, Molecular Biometrics aims to enhance the understanding and treatment of complex health issues.

Swaptree Inc.

Series C in 2008
Swaptree is a website that allows users to trade books, CDs, DVDs and video games with other users for freeSwaptree.com provides a platform for trading among its customers. The Company offers a site where the user can freely swap new and used DVDs, CDs, video games, and books with other members. Swaptree.com conducts services in the United States.

NuPathe

Series B in 2008
NuPathe Inc. is a specialty pharmaceutical company dedicated to developing and commercializing innovative therapies for neurological and psychiatric disorders. The company's flagship product is Zecuity, a transdermal system utilizing sumatriptan for the acute treatment of migraines in adults. In addition to Zecuity, NuPathe is advancing a pipeline of product candidates, including NP201, designed for the continuous treatment of Parkinson's disease, and NP202, aimed at the long-term management of schizophrenia and bipolar disorder. Both candidates leverage the company's proprietary Long-Acting Delivery technology, which facilitates extended medication release through biodegradable implants. Founded in 2005 and based in Malvern, Pennsylvania, NuPathe operates as a subsidiary of Teva Pharmaceutical Industries Limited. The company actively seeks partnerships to enhance the commercial potential of its products in the United States and internationally.

Portico Systems

Venture Round in 2008
Portico's technology enables healthcare organizations to design, build, service and provide value-based reimbursement to their complex provider networks. It also provides the ability to align and automate key network management activities including, provider enrollment, credentialing, contracting and pricing.

Alverix

Series A in 2008
Alverix focuses on producing low cost, handheld reader devices with the accuracy and precision of laboratory instrumentation. The company partners with diagnostic and OEM manufacturers seeking to increase current test accuracy, improve the portability of existing tests, or develop new assays for use in physician offices, laboratory outreach locations, retail clinics, and patient homes. With strength in product design, product development, and high volume manufacturing, Alverix is leading the transition of diagnostic testing from the laboratory to all locations where immediate results are critical to patient care.

Bridgevine

Series B in 2007
Bridgevine Inc. offers a software-as-a-service (SaaS) marketing automation solution designed to enhance digital commerce. Its platform enables users to effectively reach customers with tailored offers, optimizing product positioning and facilitating cross-selling across various devices, including mobile and desktop. The company's Audience Optimization tools help marketers engage consumers at different stages of their shopping journey, while the Mover Media Program utilizes proprietary audiences to enhance marketing efforts. Additionally, Bridgevine provides Acquily, a referral platform for customer acquisition, and a Digital Engagement and Customer Acquisition Suite that includes various commerce and social engagement applications. The firm also delivers professional services and proprietary distribution channels for industries such as telecommunications, energy, and retail. Founded in 2003 and based in Vero Beach, Florida, Bridgevine was previously known as Broadband National, Inc. and became a subsidiary of Updater, Inc. in December 2019.

Cellumen

Series B in 2007
Cellumen specializes in cellular systems biology solutions that enhance drug discovery and safety assessment processes for biopharmaceutical researchers. By providing advanced tools for early safety evaluation and discovery toxicology, Cellumen helps organizations improve the accuracy of predicting drug efficacy and safety, ultimately reducing failure rates and development costs. The company's innovative approach addresses the complexities of disease and safety, making it a valuable partner for leading institutions such as the Mayo Clinic, Hamamatsu Photonics K.K., the EPA, FDA, NIH, and prominent pharmaceutical companies. Through its commitment to advancing drug development, Cellumen plays a crucial role in the biopharmaceutical industry.

Avid Radiopharmaceuticals

Series C in 2007
Avid develops molecular imaging agents to aid medical management of chronic human diseases. They are located in Philadelphia, PA. Their mission is to develop new molecular imaging agents capable of changing the medical management of significant, chronic human diseases by identifying the first stages of pathological change, potentially assisting in earlier diagnosis, and better management and development of new therapies.

Authentium

Series B in 2007
Authentium, Inc. provides security software and services. It offers SafeCentral, a secure Internet that is designed to enable protected e-commerce; and Command Antivirus, an antivirus product. The company's technologies are used by software providers. Authentium, Inc. was founded in 1999 and is based in Palm Beach Gardens, Florida.

Beyond.com

Series A in 2007
Beyond.com, Inc. operates an online career network to connect job seekers and employers through career channels, and industry and regional communities. Beyond.com, it’s all about focus – and results. You identify the candidates you want to reach, and we’ll help you target them through relevant industry, local and specialty channels. Using our precise targeting abilities, we are able to deliver quality results through recruitment advertising, email marketing, mobile and social channels, and other highly effective tactics. A focused search means more qualified candidates. Get started today, with Beyond.com.

Advanced BioHealing

Series C in 2007
Advanced BioHealing is an industry leader in the science of regenerative medicine. The Company is focused on the commercialization of cell-based and tissue-engineered products. It currently markets the FDA-approved product Dermagraft®, for diabetic foot ulcers. Additionally, the Company's development pipeline includes a next-generation bioengineered tissue product which is in clinical trials. ABH is a privately held company with research & development offices in New York, NY and manufacturing operations in La Jolla, CA.
Advantedge Healthcare Solutions, Inc. designs and develops software for the healthcare industry. The company offers medical billing software. Additionally, it provides radiology, cardiology, anesthesia and pain management, neonatology, internal medicine, and multi specialty medical billing services. The company also offers revenue cycle management services to physicians and medical billing companies. It caters to hospitals and office based specialty physician practices. Advantedge Healthcare Solutions, Inc. was founded in 1999 and is based in Warren, New Jersey.

Portico Systems

Series A in 2006
Portico's technology enables healthcare organizations to design, build, service and provide value-based reimbursement to their complex provider networks. It also provides the ability to align and automate key network management activities including, provider enrollment, credentialing, contracting and pricing.

NuPathe

Series A in 2006
NuPathe Inc. is a specialty pharmaceutical company dedicated to developing and commercializing innovative therapies for neurological and psychiatric disorders. The company's flagship product is Zecuity, a transdermal system utilizing sumatriptan for the acute treatment of migraines in adults. In addition to Zecuity, NuPathe is advancing a pipeline of product candidates, including NP201, designed for the continuous treatment of Parkinson's disease, and NP202, aimed at the long-term management of schizophrenia and bipolar disorder. Both candidates leverage the company's proprietary Long-Acting Delivery technology, which facilitates extended medication release through biodegradable implants. Founded in 2005 and based in Malvern, Pennsylvania, NuPathe operates as a subsidiary of Teva Pharmaceutical Industries Limited. The company actively seeks partnerships to enhance the commercial potential of its products in the United States and internationally.

Rubicor Medical

Series C in 2006
Rubicor Medical is develops and distributes technologically advanced, disposable, non-invasive, breast biopsy devices.

Authentium

Series A in 2006
Authentium, Inc. provides security software and services. It offers SafeCentral, a secure Internet that is designed to enable protected e-commerce; and Command Antivirus, an antivirus product. The company's technologies are used by software providers. Authentium, Inc. was founded in 1999 and is based in Palm Beach Gardens, Florida.

Acsis

Acquisition in 2005
Acsis, Inc. provides track and trace solutions for supply chain safety and security. The company offers process-automation platforms, pre-built processes and workflows, appliances, automated SAP integration, and serialization solutions, which automates data collection, streamlines manufacturing and distribution processes, and provides real-time access to supply chain information. Acsis is the leader in real-time track and traceability software that enables effective recall management, anti-diversion, and anti-counterfeiting measures for the CPG, Life Sciences and Chemical industries. By using Acsis ProducTrak software, organizations can track and trace products through its entire lifecycle - from the raw materials to finished goods. But true product visibility doesn't stop there. Tracking products in real-time at the item level through packaging, rework, repacking, adding to case and pallets, moving through the distribution channel, and finally to end user - such as a hospital or retail store - is what Acsis is known for. This type of visibility provides the data needed to pinpoint products for recall returns or highlights suspect areas in the distribution network where diversion or shrink is suspected. The company was founded in 1996 and is based in Marlton, New Jersey.

NexTone Communications

Series D in 2005
NexTone Communications, headquartered in Rockville, Md., is focused on delivering Internet-based solutions for voice and data convergence to service providers. NexTone is in touch with the needs of the communications industry and is building products and solutions that facilitate the delivery of next generation applications. NexTone Communication's solutions represent what's next in convergence.

Ventaira Pharmaceuticals

Series C in 2005
Ventaira Pharmaceuticals is an emerging specialty pharmaceutical company focused on the development of new inhalation products by utilizing its novel proprietary electrohydrodynamic (EHD) aerosolization and formulation technologies.

NexTone Communications

Series C in 2004
NexTone Communications, headquartered in Rockville, Md., is focused on delivering Internet-based solutions for voice and data convergence to service providers. NexTone is in touch with the needs of the communications industry and is building products and solutions that facilitate the delivery of next generation applications. NexTone Communication's solutions represent what's next in convergence.