Recombinetics
Recombinetics, Inc. is a biotechnology company that specializes in the development and commercialization of gene editing technologies aimed at enhancing human health and improving animal agriculture. Founded in 2008 and based in Eagan, Minnesota, the company provides gene-edited pig models for medical clinics to facilitate testing in human cardiac therapeutics. Its proprietary TALENs technology allows for precise gene editing in large animals, supporting advancements in biomedical research, regenerative medicine, and improving animal welfare and productivity. By manipulating deoxyribonucleic acid (DNA) samples, Recombinetics enables the addition and activation of genes, thereby addressing health challenges and enhancing livestock productivity through precision breeding techniques.
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Makana Therapeutics
Acquisition in 2020
Makana Therapeutics is a biotechnology company based in Miami, Florida, established in 2009. The company specializes in developing genetically modified swine that exhibit reduced xenoantigen expression, facilitating the transplantation of human-compatible cells, tissues, and organs from these animals. By employing simplified genetic techniques and optimized pig cloning methods, Makana aims to streamline the development process for xenotransplantation products. The company's focus encompasses a diverse pipeline, including transplantable organs and tissues for vital functions such as kidney, heart, lung, liver, blood, and pancreatic islets. Through this innovative approach, Makana Therapeutics seeks to address the critical shortage of donor organs and enhance patient outcomes with safer and more effective transplantation options.
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