X-Chem

X-Chem, Inc. is a biotechnology company based in Waltham, Massachusetts, founded in 2009. The company specializes in discovering small molecule leads for high-value therapeutic targets, utilizing its innovative DNA-Encoded Library (DEL)-based discovery services. X-Chem's approach involves the iterative combinatorial synthesis of small molecules, which are linked to DNA tags that document their synthetic history. This unique methodology enables the efficient generation of novel therapeutics, positioning X-Chem as a key player in the biotechnology sector.

David Hagerman

CFO

David Werry

Director

3 past transactions

Glamorous AI

Acquisition in 2021
Glamorous AI is a developer of an advanced artificial intelligence-based drug discovery platform that focuses on low-data drug discovery. The platform utilizes AI to identify and optimize novel chemical scaffolds and screen extensive chemical libraries. By leveraging a large repository of pre-trained and customizable AI models, Glamorous AI addresses the challenges posed by sparse, noisy, and limited data. This innovative approach enables researchers to explore complex compounds and facilitates the discovery of first-in-class therapeutics, ultimately aiming to drive advancements in medicine and contribute to curing diseases.

ComInnex

Acquisition in 2021
ComInnex is a global provider of synthetic chemistry services and novel chemical technologies, supporting early-stage drug discovery for pharmaceutical companies, biotech startups, academic institutions, and government agencies worldwide. The company offers small molecule design, chemical library development and synthesis, project management, and customer service, prioritizing open communication, quick reaction times, and confidentiality to meet clients' needs efficiently.

lntelliSyn

Acquisition in 2021
IntelliSyn providers of medicinal chemistry support in North America. Our team of experienced scientists (>80% PhD), at our state-of-the-art facilities in Montreal, specializes in identifying novel leads and optimizing them as successful clinical candidates for our collaborators across Major Pharma and Biotech. IntelliSyn provide discovery support (computational chemistry, design, synthesis, and DMPK) where innovation, intellectual property security, and proven delivery-expertise are needed on an expert basis. Our discipline expertise ranges across CNS, oncology, metabolic diseases as well as other specialized areas including structure-based design, GPCR modulators, and ion channel modulators.
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