X-Chem

X-Chem, Inc. is a privately held biotechnology company located in Waltham, Massachusetts, founded in 2009. The company specializes in discovering small molecule leads for high-value therapeutic targets, utilizing its innovative DNA-Encoded Library (DEL) technology. This approach allows X-Chem to provide drug discovery services through the iterative combinatorial synthesis of small molecules, which are linked to DNA tags that document their synthetic history. By focusing on the generation of novel small molecule therapeutics, X-Chem aims to advance healthcare through its cutting-edge biotechnological services.

David Hagerman

CFO

David Werry

Director

3 past transactions

Glamorous AI

Acquisition in 2021
Glamorous AI develops an artificial intelligence-based drug discovery platform that focuses on low-data scenarios in pharmaceutical research. The platform utilizes AI to identify and optimize novel chemical compounds, facilitating the discovery of new medicines by analyzing prior experimental results. It is designed to handle sparse, noisy, and small datasets, making it particularly effective for tackling complex drug discovery challenges. By leveraging a large repository of pre-trained and customizable AI models, Glamorous AI enables researchers to screen extensive chemical libraries and address novel and first-in-class therapeutic targets, ultimately driving innovation in drug development and contributing to the advancement of treatments for various diseases.

ComInnex

Acquisition in 2021
ComInnex specializes in synthetic chemistry services and innovative chemical technologies, primarily supporting early-stage drug discovery. The company operates as a chemistry research organization that emphasizes open communication and adaptability to meet client needs. ComInnex provides a range of services, including small molecule design, chemical library development and synthesis, project management, and customer support. Its clientele includes pharmaceutical companies, biotechnology start-ups, academic institutions, non-profit organizations, and government agencies worldwide. The company is committed to ensuring both timeliness and confidentiality in its operations.

lntelliSyn

Acquisition in 2021
IntelliSyn providers of medicinal chemistry support in North America. Our team of experienced scientists (>80% PhD), at our state-of-the-art facilities in Montreal, specializes in identifying novel leads and optimizing them as successful clinical candidates for our collaborators across Major Pharma and Biotech. IntelliSyn provide discovery support (computational chemistry, design, synthesis, and DMPK) where innovation, intellectual property security, and proven delivery-expertise are needed on an expert basis. Our discipline expertise ranges across CNS, oncology, metabolic diseases as well as other specialized areas including structure-based design, GPCR modulators, and ion channel modulators.
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