Lewis & Clark Ventures

Lewis & Clark Ventures, established in 2015, is a St. Louis-based venture capital firm that invests in early-stage, high-potential B2B software, fintech, and digital health companies. Founded by former operators, the firm aims to be a trusted partner to entrepreneurs, supporting their growth and helping them achieve significance. They focus on innovative companies in the Midwest and other overlooked geographies, providing capital and expertise to drive scale and success.

Greg Fleissner

Associate

Ben Hillman

Operating Partner

Brian Hopcraft

Managing Director and Founder

Arpan Majumder

Vice President

Johanna Mennona

Analyst

Nick Nardacci

Senior Associate

Michael Rockhold

Principal

Matt Shandy

Associate

Tim Spihlman

Managing Director

Rohan Verma

Principal

Past deals in Missouri

SureCam

Series B in 2025
SureCam, LLC is a provider of network-connected vehicle cameras and tracking technology focused on enhancing fleet safety and accountability. Established in 2018 and based in St. Louis, Missouri, the company offers a range of video telematics solutions, including forward-facing and dual-facing dash cameras that capture critical incident footage and driving data in real time. SureCam’s products are designed for various clients, including global commercial fleets, independent fleet operators, and insurance firms, aiming to protect against false allegations and unsafe driving practices. With features such as cloud storage, real-time monitoring, and an online platform, SureCam helps businesses reduce claims costs and improve overall fleet management efficiency.

Sailes

Series A in 2023
Saile is a company that leverages artificial intelligence to enhance sales efficiency for leaders and organizations. Its innovative technology, known as Sailebots, automates a wide range of prospecting tasks, significantly reducing the time spent on manual labor while increasing revenue opportunities. Sailebots are capable of managing the entire prospecting lifecycle, which includes finding contacts, scheduling meetings, data cleansing, and summarizing reports related to prospective companies. This patent-pending digital labor solution is currently operational in 29 countries and supports multiple languages, making it a versatile tool for global sales teams. Headquartered in Kansas City, Missouri, Saile employs a diverse workforce distributed across various locations worldwide.

SureCam

Private Equity Round in 2022
SureCam, LLC is a provider of network-connected vehicle cameras and tracking technology focused on enhancing fleet safety and accountability. Established in 2018 and based in St. Louis, Missouri, the company offers a range of video telematics solutions, including forward-facing and dual-facing dash cameras that capture critical incident footage and driving data in real time. SureCam’s products are designed for various clients, including global commercial fleets, independent fleet operators, and insurance firms, aiming to protect against false allegations and unsafe driving practices. With features such as cloud storage, real-time monitoring, and an online platform, SureCam helps businesses reduce claims costs and improve overall fleet management efficiency.

NewLeaf Symbiotics

Series C in 2017
NewLeaf Symbiotics, Inc. is an agriculture technology company based in Saint Louis, Missouri, dedicated to the research, development, and commercialization of beneficial symbiotic bacteria aimed at enhancing plant health and increasing crop yields. The company focuses on naturally occurring bacteria, particularly pink pigmented facultative methylotrophs, which are utilized across various agricultural sectors, including row crops, vegetables, fruits, and ornamental plants. NewLeaf Symbiotics conducts extensive laboratory, greenhouse, and field trials to validate the effectiveness of its products, providing farmers with sustainable solutions to combat plant diseases and improve agricultural productivity. Originally founded as TrophoMax, LLC in 2011, the company rebranded in July 2012 to better reflect its mission and objectives in the agricultural biotechnology space.

Adarza BioSystems

Series C in 2017
Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, founded in 2008. The company specializes in developing a rapid and label-free biological assay platform that measures clinical and point-of-care samples. This innovative platform employs diagnostic arrayed imaging reflectometry (AIR) to enable the simultaneous detection of hundreds of analytes from a single drop of fluid, allowing healthcare professionals to conduct sophisticated tests with high sensitivity and specificity. By significantly reducing the time required for testing, Adarza BioSystems aims to enhance diagnostic capabilities in various healthcare settings.

Adarza BioSystems

Series B in 2016
Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, founded in 2008. The company specializes in developing a rapid and label-free biological assay platform that measures clinical and point-of-care samples. This innovative platform employs diagnostic arrayed imaging reflectometry (AIR) to enable the simultaneous detection of hundreds of analytes from a single drop of fluid, allowing healthcare professionals to conduct sophisticated tests with high sensitivity and specificity. By significantly reducing the time required for testing, Adarza BioSystems aims to enhance diagnostic capabilities in various healthcare settings.

Automation Service

Acquisition in 2013
Automation Service Inc. is a remanufacturer and distributor of process control equipment, serving various industries including municipal, petroleum, paper and pulp, and chemicals. The company specializes in remanufacturing a wide range of products such as transmitters, regulators, control valves, flow meters, and controllers, as well as offering original equipment manufacturer products like gauges and diaphragm seals. Based in Earth City, Missouri, Automation Service is committed to recycling and restoring used process control products, providing custom-built solutions alongside on-time delivery and comprehensive customer support. Founded in 1956, the company has established itself as a significant player in the automation and remanufacturing sector and operates as a subsidiary of FTL Nimbus LLC.
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