KCRise Fund is a Kansas City, Missouri-based venture capital firm focused on early-stage investments in Kansas and western Missouri. Founded in 2016 as part of the KCRising initiative to build regional capacity and scale local businesses, it backs software, information technology, and business-to-business sectors, including SaaS, supply chain/logistics, digital health, GovTech, and HRTech, as well as energy, financial services, and healthcare. The firm typically participates in seed and early-stage rounds and co-invests with other institutional investors, with multiple vintages launched to support the region's growth.

Flyover Capital is a venture capital firm based in Overland Park, Kansas, founded in 2014. It invests in early-stage technology companies, primarily B2B software, across the United States, with a focus on sectors such as finance, insurance, logistics, real estate, and cybersecurity, alongside broader information technology opportunities. The firm seeks to back entrepreneurs in the Flyover region and provides active support to portfolio companies through both favorable and challenging times, aiming to help them scale and succeed. By committing early capital and offering resources beyond funding, Flyover Capital emphasizes conviction and long-term partnership with teams building practical technology solutions.

Stray Dog Capital is a venture capital firm that invests in early-stage companies developing alternatives to animal use in the supply chain. It backs startups across the food, beverage, and biotechnology sectors in the United States and Europe, providing capital and strategic support to help grow sustainable businesses. The firm is based in Leawood, Kansas.

Nueterra Holdings is a healthcare company that develops, manages, and owns facilities, and provides a broad suite of services for consumers, employers, and providers. It offers solutions such as incentive-based health programs, population health management, physician strategy and alignment, health reform and ACO strategy, claims and benefits consulting, and international medical travel with concierge services. The company also provides provider services including electronic medical record sharing, financial analytics, revenue cycle management, patient billing, real estate, group purchasing, capital funding, bundled payments, and management services. In addition, Nueterra offers medical exchange and concierge capabilities that connect physicians, patients, and care coordinators; international care team collaboration; multilingual concierge services; analytics and reporting; and HIPAA-compliant communications. Founded in 1997 and based in Leawood, Kansas, Nueterra operates in the United States and several international locations such as Costa Rica, the Dominican Republic, Ecuador, Mexico, the Cayman Islands, Barbados, and Guatemala.

Mid-America Angels is a regional network of accredited investors that identifies and funds early-stage companies. It participates in seed, Series A, and Series B rounds depending on the capital raise and provides a framework to pool the members’ knowledge, experience, and investment capital. Founded in 2006, the organization is based in Kansas and Oklahoma and focuses on the Kansas-Missouri region around Kansas City, typically investing between $250,000 and $1,500,000 per opportunity.

Leawood Venture Capital is a Leawood, Kansas-based venture capital firm founded in 2016 that invests in technology-driven startups across the United States. The firm focuses on early-stage and growth opportunities in sectors such as artificial intelligence and machine learning, data analytics, cybersecurity, edge computing, mobile and wireless, fintech, automation and infrastructure, Internet of Things, software as a service, platform as a service, robotics, energy technology, and advanced materials. It has raised multiple funds and has backed more than 25 portfolio companies. The team leverages deep market and technology expertise and maintains broad national relationships to access leading deals, founded by successful founders and experienced operators who aim to add value through hands-on operational support.

OpenAir Equity Partners is a venture capital firm established in 2008 and based in Overland Park, Kansas. It concentrates on early-stage technology startups, with a focus on mobile, wireless, and connected-device companies.

Patheous Health offers Dysphagia Rx, a platform of diagnostic and therapeutic services. The platform improves outcomes, lower cost, and ensure that providers and patients have access to care. The company closed its venture equity funding round in early 2020 and acquired MBS Envision. Michael Peck and Correy Trupp formed the company in Leawood, Kansas in 2019.

Koch Disruptive Technologies is a venture capital firm founded in 2017 and based in Wichita, Kansas. It pursues investments in healthcare, supply chain and manufacturing, cybersecurity, fintech, semiconductors, connectivity, enterprise software and energy transformation, and provides strategic support to portfolio companies through Koch Labs.

NQV8 is a venture capital firm based in Manhattan, Kansas, founded in 2017. It focuses on investments in the pet industry, with emphasis on innovations in pet food and nutrition. The firm seeks opportunities across early and growth stages that develop novel ingredients, formulations, and delivery systems for companion animals, aiming to support companies that advance pet wellness and sustainability. NQV8 leverages market knowledge of the pet sector to guide portfolio companies and help them scale.

Founded in 2022, Iron Prairie Ventures is a venture capital firm based in Leawood, Kansas. It invests in industrial technologies with the potential to drive innovation and progress across manufacturing, infrastructure, construction, supply chain, and logistics sectors.

Blackbird Ventures is an Australasian venture capital firm founded in 2012 that backs technology startups from idea to IPO, investing from seed to later stages across Australia and New Zealand. The firm focuses on ambitious founders and aims to foster generational ownership. Its portfolio includes notable early rounds such as Canva and CultureAmp, and totals over 100 companies with a value exceeding $7B.

Serra Ventures is a venture capital firm based in Champaign, Illinois. Founded in 2008, it invests in technology companies at early and growth stages across the United States, with select international activity, focusing on information technology, deep technology, instrumentation, devices, B2B software as a service, and agricultural technologies.

Index Ventures is a venture capital firm founded in 1996 and based in London with additional offices in San Francisco and Geneva, supporting entrepreneurs shaping technology-driven global businesses by investing across early and growth stages in software, TMT, and related sectors including artificial intelligence, data, fintech, healthcare, and mobility, and partnering with founders to scale companies globally.

Morpheus Ventures is a Los Angeles-based venture capital firm founded in 2016 that makes early-stage investments in technology companies across data analytics, machine learning, robotics, transportation and software as a service, including blockchain and frontier technologies, with a focus on consumer-to-enterprise applications.

Werth Ventures, based in Woodbridge, Connecticut, is a family office established in 2009 that makes investments across the healthcare sector, from seed to late-stage opportunities. The firm focuses on pharmaceuticals, biotechnology, medical devices, equipment, distribution, facilities, and managed health care, and participates in angel investing to support startup companies in pharmaceutical, veterinary, and medical device fields. Its activity includes funding projects aiming to develop cancer treatments, cardiovascular therapies, pain management, and innovative diagnostics and imaging technologies, as well as autoinjector devices and point-of-care tests. Werth Ventures seeks to back early and growth-stage ventures with potential to advance medical science and patient care.

Ulu Ventures is a Palo Alto, California-based seed- and early-stage venture capital firm focused on technology-driven startups across IT, software, internet-enabled services, EdTech, FinTech, IoT, digital media, and related sectors in the United States, with a Bay Area emphasis. Founded in 2008, the firm backs diverse entrepreneurial teams and frequently co-invests with other angels or venture funds in early rounds. Ulu is noted as the first Latina-led venture fund in Silicon Valley and is among the largest in the country by assets under management, with over $200M.

Service Provider Capital is a Colorado-based venture capital firm founded in 2014 that funds seed-stage technology companies across domains such as artificial intelligence, machine learning, blockchain, cybersecurity, fintech, e-commerce, education technology, hardware, robotics, information technology, health tech, and cannabis. The firm also co-invests in Series A rounds led by institutional venture funds, providing capital and guidance to startups in the United States, including the Midwest and Southeast regions.

Prospect Capital Corporation is a publicly traded business development company that provides flexible debt and equity capital to middle-market companies in the United States and Canada. It emphasizes sponsor-backed and direct-lending transactions, offering private debt and private equity solutions to both sponsor-owned and independent middle-market businesses across multiple industries. The company participates in growth financings, acquisitions, recapitalizations, and other structured financings, often through various debt instruments and equity investments, and seeks to support clients with tailored capital solutions. By deploying capital across diverse sectors, Prospect Capital aims to generate steady returns for investors while focusing on the middle market.

RET Ventures is a Park City, Utah-based venture capital firm founded in 2017 that specializes in real estate technology. It invests in startups developing technology for real estate operations, with a focus on the rental sector in multifamily and single-family housing. The firm leverages a network of strategic investors who own nearly one million rental units, providing portfolio companies with early market access and practical insights. This collaboration supports the growth of rent tech solutions by connecting technology teams with property owners and operators.

Avanta Ventures is the corporate venture capital arm of CSAA Insurance Group, based in Mountain View, California. The firm invests in insurtech, mobility and risk-adjacent sectors across the United States, offering portfolio companies time, resources and industry expertise beyond capital. It supports startups through internal CSAA capabilities and external mentors, aiming to accelerate product-market fit in the insurtech space. Avanta Ventures operates Avanta Studios, a three-month program that provides funding and a B2B engagement-focused curriculum to help participants validate and scale their offerings with guidance from CSAA professionals and external subject-matter experts. The venture unit emphasizes areas such as AI, analytics and connected devices to improve customer experience in insurance and related markets.

TechNexus Venture Collaborative is a Chicago-based venture platform that brings together corporations and entrepreneurs to create new business models, products, and scalable market access. The initiative combines capital investment, incubation, and collaboration to accelerate opportunities, connecting leading companies with hundreds of startups since its founding in 2007 and earning a reputation as one of the most active venture investors in the United States. The organization targets investments across sectors including audio and consumer electronics, B2B software, health and wellness, manufacturing, marine and outdoor recreation, media production, mobility, and retail.

Plow Ventures is an early-stage venture capital firm focused on US-based B2B vertical SaaS and FinTech companies, investing from pre-seed through Series A. The firm traces its roots to Tenzing.vc, founded in 2021, and was renamed Plow Ventures as part of its evolution.

MatterScale Ventures is a venture capital firm founded in 2019 and headquartered in New York. It focuses on early-stage investments in Latin America and the United States, targeting companies in education, healthcare, technology, financial services, housing, security, and employability. The firm aims to bridge the seed-stage funding gap for Latin founders.

McKesson Corporation provides medicines, pharmaceutical supplies, information and care management products and services across the healthcare industry, operating in two segments. The company distributes medical supplies through its McKesson Medical-Surgical unit, offering medical supplies, healthcare solutions, distribution services and clinical resources, and provides pharmacy outsourcing services to hospitals through McKesson Medication Management, supporting healthcare providers, pharmacies and patients by delivering products and enabling information flow and care management across the healthcare system.

Missouri Technology is a venture capital firm based in Jefferson City, Missouri, investing in Missouri-based high-tech companies across life sciences, animal health, applied engineering, biomedical science, defense and homeland security, plant science, and technology, with a focus on promoting entrepreneurship and the growth of high-tech companies in the state.

Valor Ventures is a venture capital firm based in Atlanta, Georgia, that invests in early-stage and seed companies across the Southeast United States, with an emphasis on underrepresented and female-led teams. The firm concentrates on B2B AI and SaaS, software, fintech, platform software (PaaS), consumer tech, and health tech, prioritizing companies with at least one female founder and aiming to support the demographic shift toward a minority-majority economy. Valor typically makes seed investments in the range of 1-2 million and targets opportunities outside Silicon Valley, notably along the East Coast and Southeast. The firm emphasizes inclusive entrepreneurship and operates Startup Runway, a major pitch event for underrepresented founders, supporting founders through its network of investors and institutional partners.

Tiger Global Management is an investment firm founded in 2001 by Charles (Chase) Coleman. It allocates capital across public and private markets worldwide, with a focus on technology-enabled growth opportunities. The firm pursues public equity strategies, including long/short and growth investments, and private equity across early- to late-stage companies in multiple industries, seeking high-quality growth opportunities and guiding portfolio companies through their lifecycle.

AirTree Ventures is a Sydney-based venture capital firm founded in 2014 that backs Australian and New Zealand founders building technology companies. It focuses on early-stage and growth investments across software, internet, TMT, and related sectors, supporting portfolio companies with extensive resources to accelerate product-market fit and scale to global markets. The firm’s portfolio includes Canva, Go1, Employment Hero, Pet Circle, Immutable, and Linktree, reflecting a track record of backing category-defining technology leaders in the region. AirTree operates a family of funds, including seed and growth vehicles, targeting investments across Australia and New Zealand and offering a hands-on approach to company-building.

Royal Street Ventures is a venture capital and private equity firm based in Park City, Utah, with an additional office in Kansas City, Missouri. The firm focuses on early-stage technology companies and seeks opportunities in undercapitalized markets across the Mountain West, Midwest, Pacific Northwest, and California. It also targets sectors such as health and wellness, transportation and logistics, fintech, education, consumer products, and specialized manufacturing. Royal Street Ventures typically invests in seed and early-stage rounds and may participate in growth capital, often engaging with portfolio companies through board roles to provide strategic guidance and governance.

M25 is a Chicago-based venture capital firm focused on the Midwest. Founded in 2015, it backs pre-seed and seed-stage technology companies headquartered in the Midwest and Great Lakes region, and has invested in more than 90 startups across numerous cities and states. Led by Victor Gutwein and Mike Asem, M25 employs an analytical, collaborative approach to portfolio-building across software, information technology and other tech-enabled sectors. The firm aims to support the regional startup ecosystem by providing early-stage capital and guidance to founders as they scale their businesses.

Canaan Partners is a San Francisco-based venture capital firm founded in 1987 that operates globally with offices in Israel and India. It focuses on early-stage investments in technology and healthcare, including software, fintech, enterprise/cloud, marketplaces, digital health, biopharma, and medtech, and it has a history of backing startups that achieve exits.

FCA Venture Partners is a Nashville-based venture capital firm with roots in Clayton Associates and the McWhorter family. Founded in 1996, it has a long history of investing in healthcare entrepreneurs and aims to build sustainable businesses by providing strategic value to portfolio companies. The firm backs seed- to later-stage companies across healthcare, healthcare technology, software, SaaS, and technology-enabled services in the United States, and it operates as a registered investment adviser. By combining capital with hands-on guidance, FCA Venture Partners supports growth-oriented companies seeking to improve care quality and patient experience while expanding market reach.

IGNIA is a Mexico-based venture capital firm founded in 2007 that concentrates on early-stage investments in health, financial services, education and technology, with a focus on solving fundamental needs for people at the base of the pyramid in Latin America. It backs companies across fintech, healthtech, edtech, SaaS, e-commerce and related sectors that serve low-income populations and expand access to essential services. The firm operates funds targeting impact and growth, with a regional emphasis on Latin America, including Mexico, and typically invests several million dollars per company while seeking governance participation to support scale.

Gaingels is a venture investment organization focused on LGBTQ+-founded and led companies and their allies, investing across stages from pre-seed to pre-IPO and maintaining a global portfolio. Founded in 2014 and based in New York, it operates as a syndicate with more than 130 portfolio companies and around $70 million deployed. The organization supports inclusive leadership by backing ventures that promote diverse C-suite and board representation and actively assists portfolio companies in recruiting diverse executive talent. It also fosters a global community of industry leaders, investors, operators, and entrepreneurs who pursue positive social change through business and successful investments.

Health Velocity Capital is a San Francisco-based investment firm that focuses on healthcare software, services, and healthtech companies in the United States. It targets growth-stage opportunities and supports entrepreneurs and investors toward a high-quality, customer-friendly, affordable, and sustainable healthcare system. The firm engages in venture capital and growth investments, backing innovative healthcare technology and services in the U.S.

Goodwater Capital is a California-based venture capital firm founded in 2014 and headquartered in Burlingame. It focuses on early-stage investments in consumer technology and related sectors, including housing, financial services, software, healthcare, education, and entertainment. The firm seeks to empower exceptional entrepreneurs solving pressing problems and believes consumer technology can reshape culture and the global economy. By backing founders who create products and platforms that consumers love, Goodwater aims to drive significant, scalable impact and improve billions of lives.

Battery Ventures is a technology-focused venture capital firm based in Boston, Massachusetts, founded in 1983. It invests in category-defining technology companies across sectors such as application software, infrastructure software, consumer internet and mobile services, industrial technologies, and life science tools. The firm supports growth across various stages and geographies, including the United States, Europe, and Israel, with emphasis on software, TMT, and related tech-enabled opportunities. As a registered investment adviser, Battery Ventures backs companies that build scalable platforms and transformative products, helping them compete in rapidly evolving markets.

City Light Capital is a New York-based venture capital firm founded in 2004 that conducts early- and growth-stage investments in United States companies. It backs teams building category-defining solutions across education, safety and care, and the environment, as well as technology-enabled sectors such as digital health, climate, energy, agriculture, and IoT. The firm pursues impact-oriented investments designed to scale revenue and improve lives by partnering with experienced entrepreneurs to build durable, market-leading businesses. City Light emphasizes aligning financial returns with social and environmental outcomes and acts as an active, hands-on investor across a broad range of sectors addressing societal challenges.

Firebrand Ventures is an early-stage venture capital firm based in Kansas City, Missouri, founded in 2016 with offices in Austin, Texas, and Boulder, Colorado. It invests in software and technology startups across the United States and Canada, prioritizing ventures in underserved markets. The firm supports early-stage companies with capital and guidance, aiming to enable growth while reserving capital for select follow-on investments.

Lewis & Clark Ventures is a Saint Louis, Missouri-based private equity firm founded in 2014 that focuses on early-stage investments in healthcare and technology. It targets high-potential B2B software, fintech, and digital health companies and aims to be a trusted partner to entrepreneurs, providing support to help portfolio companies scale and achieve lasting impact.

Georgian Partners is a Toronto-based venture capital firm, founded in 2008, that invests in expansion and late-stage information-intensive software companies across North America. The firm backs its portfolio with a team of operators, entrepreneurs, and investment professionals to help CEOs scale, leveraging data-driven insights and information aggregation to support growth, product development, and go-to-market initiatives.

WestCap is a strategic operating and investing firm based in New York with offices in San Francisco and London. The firm partners with visionary leaders to build generational businesses, providing strategic operating support and capital to guide companies through pivotal growth stages. WestCap targets technology, fintech, experience tech, real estate tech, healthtech, infratech, and asset-light marketplaces, and operates as a registered investment adviser. The team consists of seasoned industry executives and entrepreneurs who help management teams execute growth strategies, scale operations, and drive value creation. The firm has a track record of notable investments, including Airbnb, StubHub, Ipreo, Addepar, Hopper, iCapital, SIMON, GoodLeap, and NYDIG, illustrating its broad sector reach and ability to partner with leaders at critical inflection points. WestCap emphasizes long-term partnerships and disciplined, hands-on oversight to build durable, scalable businesses.

Founded in 2014, Dolby Family Ventures is a San Francisco–based venture capital firm that backs technology and life sciences companies at early and later stages, including seed and Series A rounds. The firm focuses on sectors such as biotechnology, neuroscience, brain health, information technology software, security, connected devices, digital media, cloud services, healthcare technology, aerospace, climate tech, and other digital deep tech. Typical investments include seed rounds and follow-on funding, often collaborating with syndicate partners to support portfolio companies through multiple rounds. Dolby Family Ventures aims to partner with leading innovators to build durable, scalable technology businesses.

Mayo Clinic is a non-profit medical organization based in Rochester, Minnesota, established in 1863. It provides comprehensive medical care, education in clinical medicine and biomedical sciences, and conducts extensive medical research across a broad range of specialties. The organization integrates patient care with education and research to advance medical practice and outcomes. It also advances innovation through Mayo Clinic Platform, a Rochester-based accelerator that incubates and invests in early-stage health-tech startups in collaboration with providers, pharmaceutical and device companies, health-tech developers, and patients; and Mayo Clinic Ventures, the organization's venture arm that partners with physicians and scientists to commercialize inventions and discoveries to improve patient care and support Mayo’s education and research missions.

NextGen Venture Partners is a Baltimore-based venture capital firm focused on seed and early-stage technology companies in the United States. It differentiates itself through a large network of venture partners who collectively participate in investments, enabling broad deal sourcing, due diligence, and extensive founder support. The firm concentrates on technology sectors, including software and information technology, and operates across the United States with a national portfolio. Founded in 2011, it maintains offices in Baltimore, Boston, and Arlington, supporting portfolio companies through strategic guidance and access to its partner network.

Keiretsu Forum is an international investment community of accredited private equity investors, venture capitalists and corporate/institutional investors. Founded in San Francisco in 2000, it operates as a worldwide network that structures access to high-quality deal flow and investment opportunities through regional chapters across the United States, Europe and Asia. It is described as the world’s largest invitation-only angel investor network, with thousands of investor members who participate in funding opportunities for early- to growth-stage companies in technology, healthcare, energy, consumer products and other sectors. The forum emphasizes collaboration among members and partner resources to support due diligence, syndication and capital deployment, enabling private capital to back high-potential ventures.

Right Side Capital Management is a San Francisco-based venture capital firm founded in 2010 that invests in early-stage technology startups. It specializes in pre-seed and seed rounds for capital-efficient companies, with a focus on the United States and Canada and occasional activity in Western Europe, Israel, Australia, and New Zealand. The firm typically makes 75 to 100 investments per year, with round sizes from 50,000 to 500,000 and pre-money valuations ranging from 1,000,000 to 3,500,000. Portfolio companies are typically located outside the San Francisco Bay Area and New York City, and the firm aims to provide a clear yes or no on opportunities within about two weeks.

Acronym Venture Capital is a New York-based venture capital firm that invests in late-seed to Series A rounds in enterprise software and consumer brands, with a focus on B2B SaaS, hospitality, commerce, workflow, fintech, consumer packaged foods and beverages, proptech, cyber, and other consumer sectors. The firm prioritizes first-time and diverse founders and pursues opportunistic opportunities in New York City and rising markets. It emphasizes a value-add approach, using its network to support portfolio companies with revenue opportunities, talent recruiting, partnerships, and follow-on capital. Investments typically require at least $1 million in annual recurring revenue. The firm does not invest in companies that touch MUSH sectors: municipalities, utilities, schools, or hospitals.

Marbruck is a venture capital firm based in Darlinghurst, Australia, focused on technology companies. It operates as an open-ended group that sources, makes investments in, and provides ongoing guidance to early and growth-stage ventures. The organization operates with no outside capital and manages a diverse global portfolio of more than 30 companies spanning seed through pre-listing. By leveraging its intellectual capital, a network of partner investors, and extensive operational experience, Marbruck supports portfolio companies across the high-risk, high-reward spectrum of technology investing.