Fifty Years

Deepcell, Inc. is a biotechnology company based in Mountain View, California, that specializes in providing advanced diagnostic solutions through its innovative microfluidic imaging platform. Founded in 2015, the company focuses on delivering non-invasive tests with diagnostic-level accuracy, enabling researchers and clinicians to gain insights at the single-cell level. Deepcell's technology employs artificial intelligence to analyze and classify cells based on their morphological features, isolating viable cells for various applications in translational research, diagnostic testing, and therapeutics. By utilizing ordinary blood samples, Deepcell enhances the understanding of genetic health without the need for invasive procedures, thereby improving the diagnosis and treatment of diseases.

Gridware specializes in advanced grid monitoring solutions aimed at enhancing the safety and reliability of electrical infrastructure. The company develops a sophisticated sensing system equipped with high-precision sensor arrays and artificial intelligence to continuously analyze the electrical and mechanical behavior of grid assets. This technology detects and predicts faults by monitoring the ambient environment around power poles, allowing utilities to identify potential issues before they escalate into serious problems. By facilitating timely repairs and enabling rapid responses to environmental anomalies, Gridware's solutions help mitigate risks such as wildfires and power outages. Headquartered in the Bay Area of California, Gridware is a privately held company supported by prominent climate-tech investors.

Aalo Atomics is a clean energy company focused on the development and commercialization of small nuclear fission reactors. These compact reactors, designed for factory manufacturing, are capable of generating clean energy suitable for various applications, ranging from powering data centers to supplying energy for large cities. Aalo Atomics aims to make energy production more affordable while ensuring safety and sustainability. By harnessing nuclear energy, the company seeks to empower individuals and communities to reduce their power consumption and contribute to a cleaner energy future.

Waypoint Bio is a company focused on advancing cell therapy to treat solid tumors in cancer patients. It has developed a novel platform that integrates spatial multi-omics, utilizing proprietary methodologies enhanced by artificial intelligence and machine learning. This innovative approach facilitates the design of effective and safe cell therapies through pooled screening techniques. By optimizing the application of cell therapy, Waypoint Bio aims to improve treatment outcomes for patients battling solid tumors.

BillionToOne Inc. is a precision diagnostics company based in Menlo Park, California, that specializes in molecular testing for prenatal and oncology applications. Established in 2016, the company has developed a patented molecular counter platform capable of detecting and quantifying DNA molecules at an extraordinarily precise level. BillionToOne's flagship product, UNITY, is a noninvasive prenatal screening test that analyzes fetal cell-free DNA from a simple blood sample taken from the mother, allowing for the detection of single-gene disorders such as cystic fibrosis, spinal muscular atrophy, and beta-thalassemia. This innovative approach aims to replace more invasive procedures like amniocentesis, providing a safer and more affordable alternative for expecting mothers, particularly in developing countries. Additionally, the company is focused on oncology, offering tests that can accurately identify actionable mutations and assess tumor burden through blood samples.

The Bot Company is a startup focused on developing AI-driven robotic platforms. Their mission is to create robots that help humans save time and increase efficiency. Currently, they are operating in stealth mode.

Nabla Bio operates an autoreverse platform that facilitates the rapid discovery of novel protein variants with unique properties. By leveraging insights gained from billions of natural proteins, the company engineers these enhanced proteins for both medical and industrial applications. Through extensive experimentation, Nabla Bio develops new medicines and improves nutritional products, allowing clients to conduct complex measurements of protein function and implement innovative solutions in various fields.

Varda Space Industries, Inc. is a space manufacturing startup based in San Francisco, California, founded in 2020 by Delian Asparouhov and Trae Stephens. The company specializes in creating products in space that are intended for terrestrial applications, leveraging the unique advantages of low gravity. Varda aims to establish an infrastructure for harvesting materials from asteroids, enabling the production of new products in space. This approach not only facilitates the manufacturing of innovative goods but also promotes sustainability by reducing reliance on the destructive extraction of Earth's resources.

Cosmic Aerospace is an innovative aerospace technology company focused on advancing sustainable aviation through the development of ultra-efficient all-electric passenger aircraft. The company aims to create fully electric planes characterized by improved propulsion systems and unique airframe designs, which are intended to significantly reduce air pollution associated with regional flights. By prioritizing energy efficiency, Cosmic Aerospace seeks to facilitate a transition to more sustainable air travel, ultimately making aviation more environmentally friendly and accessible.

Planet A Foods is a company focused on producing cocoa-free chocolate made from natural ingredients. By utilizing traditional fermentation methods, the company aims to provide a sustainable alternative to traditional chocolate, allowing consumers to enjoy their chocolate cravings without the negative impacts associated with cocoa production. Planet A Foods emphasizes local food production with minimal environmental impact, striving to reduce carbon emissions and promote sustainable practices in the food industry.

Faction specializes in the development of driverless electric vehicles that combine the speed and performance of cars with the affordability of motorcycles. The company focuses on micro-delivery and ride-on-demand services, utilizing a model that integrates remote human supervision alongside autonomous technology. This approach allows Faction to bypass the limitations of fully autonomous systems, enabling quicker deployment of its services. The vehicles are designed with networked data capabilities, over-the-air software updates, and safety-critical autonomy features, ensuring a cost-effective and reliable driverless solution for clients. After completing its first prototypes, Faction is set to commence trials to further refine its offerings in the transportation sector.

Elicit is an artificial intelligence research assistant that uses language models to help users automate research workflows. This research assistant finds relevant papers without a perfect keyword match, summarizes takeaways from the papers, and extracts key information from the papers.

BIOS Health is a pioneering company focused on developing neural digital therapies by leveraging data from the human nervous system. By identifying neural biomarkers that correlate nerve activity to specific medical conditions, BIOS aims to revolutionize precision medicine. Their research offers the potential for innovative treatments for a range of chronic diseases, including hypertension, diabetes, and neurodegenerative disorders such as Parkinson's and Alzheimer's. Co-founded by experts from Cambridge University, the team includes professionals from diverse fields such as neuroscience, machine learning, and biotechnology. Additionally, BIOS is working on prosthetic connectors that standardize connections between bionic devices and neural systems, facilitating neural control and feedback for amputees. This dual approach positions BIOS at the forefront of improving the quality of life for individuals with chronic conditions and those requiring prosthetic solutions.

Gridware specializes in advanced grid monitoring solutions aimed at enhancing the safety and reliability of electrical infrastructure. The company develops a sophisticated sensing system equipped with high-precision sensor arrays and artificial intelligence to continuously analyze the electrical and mechanical behavior of grid assets. This technology detects and predicts faults by monitoring the ambient environment around power poles, allowing utilities to identify potential issues before they escalate into serious problems. By facilitating timely repairs and enabling rapid responses to environmental anomalies, Gridware's solutions help mitigate risks such as wildfires and power outages. Headquartered in the Bay Area of California, Gridware is a privately held company supported by prominent climate-tech investors.

Tangible is a climate technology company focused on building sustainable materials that are not harmful to the environment. Tangible is a unified software platform that catalyzes the adoption of sustainable building materials by allowing real estate developers, architects, and contractors to seamlessly identify, manage, and report on products that meet their carbon, environmental, and social goals. Founded in 2021 by Nicole Granath and Anneli Tostar, Tangible is headquartered in San Francisco, California, United States.

MultiOmic Health is an AI-driven start-up specializing in drug discovery for metabolic syndrome-related diseases. The company collaborates with selected healthcare providers to collect and analyze de-identified patient data and bio-samples. Its MOHSAIC® platform integrates multi-omics analysis with computational systems biology modeling and targeted laboratory experiments to develop novel precision therapeutic concepts. These concepts are then commercialized through partnerships with established biopharma companies, facilitating the creation of new therapeutic and diagnostic research and development programs. By focusing on precision medicine, MultiOmic Health aims to improve treatment options for patients suffering from metabolic syndrome.

Noya is focused on addressing climate change by retrofitting existing industrial equipment to capture carbon dioxide from the atmosphere. The company's innovative technology utilizes a non-toxic chemical blend that is added to the cooling towers of various industries without requiring any structural modifications. This approach allows for effective CO2 capture while enabling businesses to contribute to environmental sustainability. By selling the captured carbon dioxide to companies that utilize it as a raw material, Noya facilitates a practical and scalable solution for reducing carbon emissions and promoting a transition towards a carbon-negative future.

Aalo Atomics is a clean energy company focused on the development and commercialization of small nuclear fission reactors. These compact reactors, designed for factory manufacturing, are capable of generating clean energy suitable for various applications, ranging from powering data centers to supplying energy for large cities. Aalo Atomics aims to make energy production more affordable while ensuring safety and sustainability. By harnessing nuclear energy, the company seeks to empower individuals and communities to reduce their power consumption and contribute to a cleaner energy future.

Mindset Health, established in 2018, is a digital therapeutics company based in Melbourne, Australia. It operates a mobile application that uses psychotherapy and hypnotherapy to improve mental health and manage chronic health issues. The app treats irritable bowel syndrome without dietary changes, enhances sleep duration and quality, reduces anxiety and stress, and helps manage chronic pain, providing a non-addictive, safe, and cost-effective alternative to traditional treatments.

Journey Clinical is a platform that provides services to member psychotherapy practices that are independently owned and operated, and in no way owns, directs, or controls the mental healthcare clinicians providing care.

We build advanced satcom terminals

BillionToOne Inc. is a precision diagnostics company based in Menlo Park, California, that specializes in molecular testing for prenatal and oncology applications. Established in 2016, the company has developed a patented molecular counter platform capable of detecting and quantifying DNA molecules at an extraordinarily precise level. BillionToOne's flagship product, UNITY, is a noninvasive prenatal screening test that analyzes fetal cell-free DNA from a simple blood sample taken from the mother, allowing for the detection of single-gene disorders such as cystic fibrosis, spinal muscular atrophy, and beta-thalassemia. This innovative approach aims to replace more invasive procedures like amniocentesis, providing a safer and more affordable alternative for expecting mothers, particularly in developing countries. Additionally, the company is focused on oncology, offering tests that can accurately identify actionable mutations and assess tumor burden through blood samples.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Molten Industries focuses on developing clean technology aimed at decarbonizing the hydrogen market. The company provides a cost-effective and environmentally friendly method for hydrogen production, which allows chemical and heavy industries to significantly reduce their carbon emissions. Through its innovative solutions, Molten Industries contributes to the transition towards sustainable energy practices.

Harmonic Discovery is a pharmaceutical company focused on developing a platform that addresses cancer resistance mechanisms through innovative drug design. The company's platform integrates biological screening, medicinal chemistry, and computational chemistry, employing structural modeling and machine learning to predict potential clinical resistance mutations. This approach allows for the optimization of small molecule therapeutics, ensuring they effectively target cancer while minimizing undesirable off-target interactions. By combining computation with experimental data, Harmonic Discovery aims to enhance treatment outcomes for cancer patients.

Arpeggio Bio, established in 2017 and headquartered in Boulder, Colorado, specializes in developing innovative software that captures snapshots of cellular RNA activity. By combining biological assays with advanced machine learning algorithms, the company enables pharmaceutical and biotechnology firms to understand a drug's mechanism of action at low sequencing depths. Arpeggio Bio's technology reveals intricate biological networks, facilitating more informed therapeutic development.

Persephone Biome, Inc. is a San Diego-based company focused on researching and developing products and therapies that modify gut microbial metabolism, particularly in relation to cancer treatment. Established in 2017, the company is creating innovative solutions aimed at enhancing the efficacy of oncology drugs by retuning the gut microbiome. This includes the development of a pill containing beneficial gut bacteria. In addition to its therapeutics, Persephone Biome aims to offer nutritional products that support the human gut microbiome, producing functional foods and beverages that cater to the growing consumer demand for health-oriented products. The company has plans to enter clinical trials to further advance its initiatives in the field of microbiome-directed therapies.

Solving cancer resistance.

Manifold Biotechnologies, Inc. is a biotechnology company that specializes in developing platforms for the pharmacological measurement of various therapeutic protein variants. By integrating DNA technologies with machine learning, the company aims to create protein drugs that address challenging diseases. Manifold Bio's innovative approach includes a protein barcoding platform designed to enable multiplexed quantitation of protein therapeutics, thereby generating extensive data that enhances the drug development process. Founded in 2019 and located in Allston, Massachusetts, the company is focused on advancing measurement-driven design in the field of protein therapeutics.

LatchBio is a company that specializes in developing a bioinformatics platform aimed at supporting cell and gene therapy startups. Established in 2021 by Alfredo Andere, Kyle Giffin, and Kenny Workman, LatchBio provides an open-source machine learning and cloud infrastructure tailored for the biotech sector. Its platform modernizes the computing capabilities available to biotech labs by offering custom workflows, pipelines, and machine learning models that can be utilized across various scales. This infrastructure enables scientists to efficiently create bioinformatic queries without requiring extensive command-line knowledge or dealing with complex setups. By streamlining data integration and processing, LatchBio helps biotech companies accelerate therapeutic discovery and reduce engineering costs.

Boundary Layer Technologies is a startup established in 2018 that specializes in the development of high-speed container ships utilizing hydrofoil technology. This innovative approach allows the vessels to generate lift, elevating the hull above the water and significantly reducing drag. As a result, these ships offer a faster alternative for the logistics industry, particularly in ocean freight, compared to traditional methods. By focusing on enhancing delivery speeds, Boundary Layer Technologies aims to disrupt the existing airfreight market and provide a more efficient solution for transporting shipments across oceans.

Octant Bio is a biotechnology company focused on developing synthetic technology aimed at enhancing health and treating diseases. The company employs a platform that integrates synthetic biology, genome engineering, next-generation sequencing, and computational tools to measure the activity of thousands of receptor pathways in human cells. This advanced technology allows scientists to utilize machine learning techniques to engineer small molecules capable of interacting with multiple receptors, thereby creating new possibilities for the treatment of complex diseases.

Ansa Biotechnologies, Inc. is a biotechnology company based in Berkeley, California, focused on developing innovative DNA synthesis technology utilizing enzymes. Established in 2018, the company aims to improve upon traditional chemical methods of DNA synthesis that have remained largely unchanged for decades. Ansa's enzymatic approach offers significant advantages, including increased speed, accuracy, and cleanliness in the production of DNA fragments such as oligonucleotides. This technology enhances the capabilities of biological research, therapeutics, diagnostics, and biomanufacturing by enabling the synthesis of gene-length oligonucleotides. Through its advancements, Ansa Biotechnologies seeks to facilitate innovation in the fields of biological research and engineering, ultimately providing valuable services to medical researchers and contributing to the broader biotechnology landscape.

BillionToOne Inc. is a precision diagnostics company based in Menlo Park, California, that specializes in molecular testing for prenatal and oncology applications. Established in 2016, the company has developed a patented molecular counter platform capable of detecting and quantifying DNA molecules at an extraordinarily precise level. BillionToOne's flagship product, UNITY, is a noninvasive prenatal screening test that analyzes fetal cell-free DNA from a simple blood sample taken from the mother, allowing for the detection of single-gene disorders such as cystic fibrosis, spinal muscular atrophy, and beta-thalassemia. This innovative approach aims to replace more invasive procedures like amniocentesis, providing a safer and more affordable alternative for expecting mothers, particularly in developing countries. Additionally, the company is focused on oncology, offering tests that can accurately identify actionable mutations and assess tumor burden through blood samples.

Antora Energy specializes in providing zero-carbon industrial heat and power solutions for heavy industries, offering a more reliable alternative to fossil fuels. The company develops innovative thermal batteries that utilize excess solar and wind electricity to heat blocks of carbon, creating a sustainable energy source. These thermal energy storage systems effectively convert heat energy into electric energy, facilitating the electrification of heavy industry. By enabling the integration of renewable resources into the electricity grid, Antora Energy aims to deliver convenient, sustainable, and reliable electricity while significantly reducing carbon emissions on a global scale.

Zero Acre Farms is a food company focused on eliminating the reliance on harmful vegetable oils in the food industry. It offers a sustainable alternative produced through fermentation technology, utilizing microorganisms to create oils and fats that contain significantly lower levels of unhealthy fats associated with inflammation and disease. This innovative approach aims to promote healthier dietary options for consumers while addressing the environmental concerns linked to traditional oil production.

Athelas, Inc. is a healthcare company based in Mountain View, California, that specializes in developing and manufacturing in-home blood analysis devices aimed at diagnosing infections, inflammations, and malignancies. Founded in 2002, Athelas has created a portable optical unit that analyzes blood samples from a single drop, providing diagnostic reports to monitor the immune system. The company's FDA-cleared device is designed to help chronically ill patients manage their health at home, offering additional monitoring for blood pressure, weight, glucose levels, and medication adherence. This technology enables patients to monitor their immunity and assists healthcare providers in the early detection of conditions such as leukemia and other inflammatory diseases. Athelas operates as a subsidiary of MerLion Pharmaceuticals Pte. Ltd.

MultiOmic Health is an AI-driven start-up specializing in drug discovery for metabolic syndrome-related diseases. The company collaborates with selected healthcare providers to collect and analyze de-identified patient data and bio-samples. Its MOHSAIC® platform integrates multi-omics analysis with computational systems biology modeling and targeted laboratory experiments to develop novel precision therapeutic concepts. These concepts are then commercialized through partnerships with established biopharma companies, facilitating the creation of new therapeutic and diagnostic research and development programs. By focusing on precision medicine, MultiOmic Health aims to improve treatment options for patients suffering from metabolic syndrome.

64x Bio develops a platform aimed at accelerating the discovery and optimization of mammalian cell lines for biomanufacturing and therapeutics. The company employs a high-throughput discovery and screening approach combined with an integrated computational design loop to create genetically engineered cell lines tailored for the production of viral vectors. This focus is particularly relevant for cell and gene therapies, as it enhances the efficiency of viral vector production. By providing purpose-built cell lines, 64x Bio enables pharmaceutical and biotechnology companies to improve their manufacturing capacity and reduce costs, ultimately facilitating the timely delivery of innovative therapies to patients.

HealthLeap aims to enhance global health by addressing disease-related malnutrition, a critical issue that significantly impacts patient outcomes. The company has developed an AI-based clinical assistant designed for healthcare professionals, which facilitates better diagnosis and treatment of malnutrition, often referred to as the "silent killer." This condition affects 30-50% of all hospital patients and is linked to a three to five times increase in mortality during hospital stays, yet only a small percentage are accurately diagnosed. HealthLeap's tool provides automated medical calculations and data-driven recommendations, enabling clinicians to optimize treatment quality, improve clinical outcomes, and reduce healthcare costs.

Tangible is a climate technology company focused on building sustainable materials that are not harmful to the environment. Tangible is a unified software platform that catalyzes the adoption of sustainable building materials by allowing real estate developers, architects, and contractors to seamlessly identify, manage, and report on products that meet their carbon, environmental, and social goals. Founded in 2021 by Nicole Granath and Anneli Tostar, Tangible is headquartered in San Francisco, California, United States.

InVivo AI, founded in 2017 and based in Montreal, Canada, specializes in utilizing artificial intelligence to enhance pharmaceutical research and development, particularly in the area of preclinical toxicology. The company aims to streamline the drug discovery process by implementing advanced AI methods for molecular representation and de novo design, which allows for the creation of novel chemical compounds that can address complex biological challenges. Through its innovative platform, InVivo AI is positioned to significantly improve the efficiency and effectiveness of drug design, paving the way for breakthroughs in pharmaceutical science.

Nabla Bio operates an autoreverse platform that facilitates the rapid discovery of novel protein variants with unique properties. By leveraging insights gained from billions of natural proteins, the company engineers these enhanced proteins for both medical and industrial applications. Through extensive experimentation, Nabla Bio develops new medicines and improves nutritional products, allowing clients to conduct complex measurements of protein function and implement innovative solutions in various fields.

Planet A Foods is a company focused on producing cocoa-free chocolate made from natural ingredients. By utilizing traditional fermentation methods, the company aims to provide a sustainable alternative to traditional chocolate, allowing consumers to enjoy their chocolate cravings without the negative impacts associated with cocoa production. Planet A Foods emphasizes local food production with minimal environmental impact, striving to reduce carbon emissions and promote sustainable practices in the food industry.

Superdao is a platform designed to support the management and growth of decentralized autonomous organizations (DAOs) in the Web3 space. It offers tools for wallet analytics that provide organizations with insights into their dapp users, NFT and token holders, DAO voters, and quest participants. The platform features a hybrid governance system that facilitates collaborative management of decentralized application ventures, enabling users to create and customize intelligent contracts with ease. Additionally, Superdao includes a built-in member directory, treasury dashboard, and contributor management tools, which enhance decision-making and governance for DAOs. Organizations can leverage filter and export tools to build targeted lists and gain competitive insights from a database of audiences from numerous top Web3 projects.

World is a company that connects users through a privacy-focused network designed for secure digital asset management. It offers a digital currency platform that emphasizes both privacy and transparency using a permissionless blockchain. The World App enables users to securely store their World ID, manage digital assets, and access various Mini Apps, promoting global connectivity and trust. Additionally, World provides an iris-scanning device that enhances digital identity security by storing biometric information, which helps discourage spammers from creating multiple accounts. This combination of secure identity management and digital currency aims to facilitate a reliable and user-friendly digital environment.

LatchBio is a company that specializes in developing a bioinformatics platform aimed at supporting cell and gene therapy startups. Established in 2021 by Alfredo Andere, Kyle Giffin, and Kenny Workman, LatchBio provides an open-source machine learning and cloud infrastructure tailored for the biotech sector. Its platform modernizes the computing capabilities available to biotech labs by offering custom workflows, pipelines, and machine learning models that can be utilized across various scales. This infrastructure enables scientists to efficiently create bioinformatic queries without requiring extensive command-line knowledge or dealing with complex setups. By streamlining data integration and processing, LatchBio helps biotech companies accelerate therapeutic discovery and reduce engineering costs.

Journey Clinical is a platform that provides services to member psychotherapy practices that are independently owned and operated, and in no way owns, directs, or controls the mental healthcare clinicians providing care.

Unspun, Inc., founded in 2015 and based in San Francisco, California, specializes in the development of a platform that creates customized jeans using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental concerns by reducing global carbon emissions through automated and localized manufacturing processes. Unspun’s innovative approach not only eliminates pattern-cutting waste and unsold inventory but also allows for the production of jeans in under ten minutes in a zero-waste manner. Their technology is showcased through the unspun.io platform, which provides digital customization solutions for various apparel brands. With a mission to make fashion more sustainable, Unspun is positioned at the intersection of robotics and digital apparel, striving to transform the industry with its unique approach to on-demand manufacturing.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Nabla Bio operates an autoreverse platform that facilitates the rapid discovery of novel protein variants with unique properties. By leveraging insights gained from billions of natural proteins, the company engineers these enhanced proteins for both medical and industrial applications. Through extensive experimentation, Nabla Bio develops new medicines and improves nutritional products, allowing clients to conduct complex measurements of protein function and implement innovative solutions in various fields.

Talus Bio is a biotech startup focused on drug discovery, particularly in the development of therapies targeting gene regulators for cancer treatment. The company utilizes a data-enabled platform that combines functional proteomics, automated biology, and machine learning to address the challenges associated with cancer transcription factors. Its proprietary MARMOT platform employs advanced techniques such as AI, quantitative proteomics, synthetic chemistry, and computational biology to design and analyze small-molecule drugs and proteins. This innovative approach aims to enhance drug development processes in the oncology sector, facilitating advancements in gene regulation and contributing to more effective cancer therapies.

Earth AI, established in 2016 and headquartered in Parramatta, Australia, specializes in AI-driven mineral exploration. It uses satellite, geophysical, and geochemical data to generate precise geological maps and suggest locations for mineral exposure, particularly for metals like copper, lead, zinc, nickel, cobalt, vanadium, and rare earth elements. By doing so, Earth AI helps mining explorers enhance their discovery prospects while reducing operational risks and costs.

Talus Bio is a biotech startup focused on drug discovery, particularly in the development of therapies targeting gene regulators for cancer treatment. The company utilizes a data-enabled platform that combines functional proteomics, automated biology, and machine learning to address the challenges associated with cancer transcription factors. Its proprietary MARMOT platform employs advanced techniques such as AI, quantitative proteomics, synthetic chemistry, and computational biology to design and analyze small-molecule drugs and proteins. This innovative approach aims to enhance drug development processes in the oncology sector, facilitating advancements in gene regulation and contributing to more effective cancer therapies.

Nobell Foods is a biotech company based in San Francisco, California, that specializes in developing and producing animal-based food substitutes using plant materials. Founded in 2016, the company aims to transform plants into bioreactors to generate protein, unlocking their potential to create innovative food alternatives. By focusing on plant-based solutions, Nobell Foods seeks to provide sustainable options that can replace traditional animal products, contributing to a more environmentally friendly food system.

Atom Computing Inc. is a company based in Berkeley, California, that focuses on manufacturing scalable quantum computers utilizing individual atoms. Founded in 2018, the company harnesses the quantum mechanical properties of atoms to process information and address complex problems that traditional computers cannot solve. Atom Computing's technology allows for the optical control, scaling, and stabilization of these atoms, facilitating efficient quantum calculations in various fields, including drug design, computational chemistry, and general computing. Through its innovative approach, Atom Computing aims to advance the development of quantum technology and expand its applications across multiple industries.

Varda Space Industries, Inc. is a space manufacturing startup based in San Francisco, California, founded in 2020 by Delian Asparouhov and Trae Stephens. The company specializes in creating products in space that are intended for terrestrial applications, leveraging the unique advantages of low gravity. Varda aims to establish an infrastructure for harvesting materials from asteroids, enabling the production of new products in space. This approach not only facilitates the manufacturing of innovative goods but also promotes sustainability by reducing reliance on the destructive extraction of Earth's resources.

Meati Foods is a Boulder, Colorado-based company specializing in the production and sale of fungi-based meat alternatives. Founded in 2016, the company aims to provide sustainable and nutritious plant-based options that serve as an alternative to traditional meat products. Meati Foods utilizes a proprietary fermentation process to create minimally processed steaks made from natural ingredients, ensuring its offerings are free from common allergens. The company markets its products online, making them accessible to a wide audience seeking vegan food choices that are both healthy and environmentally friendly.

Mindset Health, established in 2018, is a digital therapeutics company based in Melbourne, Australia. It operates a mobile application that uses psychotherapy and hypnotherapy to improve mental health and manage chronic health issues. The app treats irritable bowel syndrome without dietary changes, enhances sleep duration and quality, reduces anxiety and stress, and helps manage chronic pain, providing a non-addictive, safe, and cost-effective alternative to traditional treatments.

BillionToOne Inc. is a precision diagnostics company based in Menlo Park, California, that specializes in molecular testing for prenatal and oncology applications. Established in 2016, the company has developed a patented molecular counter platform capable of detecting and quantifying DNA molecules at an extraordinarily precise level. BillionToOne's flagship product, UNITY, is a noninvasive prenatal screening test that analyzes fetal cell-free DNA from a simple blood sample taken from the mother, allowing for the detection of single-gene disorders such as cystic fibrosis, spinal muscular atrophy, and beta-thalassemia. This innovative approach aims to replace more invasive procedures like amniocentesis, providing a safer and more affordable alternative for expecting mothers, particularly in developing countries. Additionally, the company is focused on oncology, offering tests that can accurately identify actionable mutations and assess tumor burden through blood samples.

Yuri specializes in designing and manufacturing hardware for the aviation and aerospace industry, focusing on applications in microgravity research and experiments. The company provides an end-to-end space mission platform that includes services such as mission definition, hardware selection and development, as well as launch and return logistics. Additionally, Yuri supports researchers with a variety of advanced scientific services, including 3D cell culture growth, human disease modeling, protein and molecule analysis, synthetic biology, plant biology studies, and nanofluidics. This comprehensive approach enables researchers to access a quick and cost-effective combination of experimental hardware, facilities, and microgravity platforms.

MultiOmic Health is an AI-driven start-up specializing in drug discovery for metabolic syndrome-related diseases. The company collaborates with selected healthcare providers to collect and analyze de-identified patient data and bio-samples. Its MOHSAIC® platform integrates multi-omics analysis with computational systems biology modeling and targeted laboratory experiments to develop novel precision therapeutic concepts. These concepts are then commercialized through partnerships with established biopharma companies, facilitating the creation of new therapeutic and diagnostic research and development programs. By focusing on precision medicine, MultiOmic Health aims to improve treatment options for patients suffering from metabolic syndrome.

Gridware specializes in advanced grid monitoring solutions aimed at enhancing the safety and reliability of electrical infrastructure. The company develops a sophisticated sensing system equipped with high-precision sensor arrays and artificial intelligence to continuously analyze the electrical and mechanical behavior of grid assets. This technology detects and predicts faults by monitoring the ambient environment around power poles, allowing utilities to identify potential issues before they escalate into serious problems. By facilitating timely repairs and enabling rapid responses to environmental anomalies, Gridware's solutions help mitigate risks such as wildfires and power outages. Headquartered in the Bay Area of California, Gridware is a privately held company supported by prominent climate-tech investors.

Multiply Labs specializes in the production of personalized pharmaceutical capsules that cater to the unique needs of individual patients. The company leverages a combination of pharmaceutical science and advanced robotics technology to create these tailor-made capsules. Its innovative approach includes operating a state-of-the-art robotic manufacturing facility, which allows for the efficient production of individualized drugs at a reduced cost. Multiply Labs stands out as a pioneer in the industry, being the first to introduce 3D printed capsules, thereby transforming how medications are customized to meet the specific metabolic requirements of patients.

Substack Inc. is an online platform based in San Francisco, California, that enables independent writers to create and distribute both paid and free subscription newsletters. Founded in 2017, Substack provides a suite of user-friendly tools designed for newsletter publishing, facilitating the simultaneous publication of content to email lists and websites. The platform simplifies the process of managing subscriber payments, making it easier for writers to monetize their work directly from their audiences. Additionally, Substack offers features that help stories reach wider audiences beyond paywalls and provides customizable design templates to enhance the reading experience. Through its innovative approach, Substack empowers writers to generate income from their newsletters while connecting with their subscribers effectively.

Faction specializes in the development of driverless electric vehicles that combine the speed and performance of cars with the affordability of motorcycles. The company focuses on micro-delivery and ride-on-demand services, utilizing a model that integrates remote human supervision alongside autonomous technology. This approach allows Faction to bypass the limitations of fully autonomous systems, enabling quicker deployment of its services. The vehicles are designed with networked data capabilities, over-the-air software updates, and safety-critical autonomy features, ensuring a cost-effective and reliable driverless solution for clients. After completing its first prototypes, Faction is set to commence trials to further refine its offerings in the transportation sector.

Noya is focused on addressing climate change by retrofitting existing industrial equipment to capture carbon dioxide from the atmosphere. The company's innovative technology utilizes a non-toxic chemical blend that is added to the cooling towers of various industries without requiring any structural modifications. This approach allows for effective CO2 capture while enabling businesses to contribute to environmental sustainability. By selling the captured carbon dioxide to companies that utilize it as a raw material, Noya facilitates a practical and scalable solution for reducing carbon emissions and promoting a transition towards a carbon-negative future.

Brave Care, Inc. specializes in urgent pediatric health care services, treating a wide range of conditions, including allergies, asthma, cough, ear pain, eye issues, fever, minor fractures, and rashes. The company also offers pediatric-specific laboratory services, on-site x-ray, and light sedation for certain procedures. Founded in 2019 and based in Portland, Oregon, Brave Care operates clinics exclusively designed for children in Oregon and Texas. In addition to in-person care, the BraveCare.com website and mobile app provide nationwide pediatric advice to assist parents in supporting their children's health and development.

WorkEQ is a business development and employment agency that focuses on enhancing workplace dynamics through flexible and productive work-life balance solutions. The company has developed a platform for contact tracing and health monitoring, designed to protect individuals from infectious diseases. This platform enables organizations to quickly access data on symptom onset and identify potentially exposed employees, facilitating timely responses to prevent viral outbreaks. By prioritizing health and safety, WorkEQ aims to improve employee engagement and productivity while fostering a more flexible and inclusive work environment.

Oolu Inc. is a rapidly growing company specializing in solar home systems, providing installation, technical support, and maintenance services to households in West Africa, primarily from its base in Dakar, Senegal. With an additional office in San Francisco, the company aims to deliver affordable and reliable energy solutions to off-grid communities, particularly in rural and peri-urban areas. Oolu's solar home systems typically include adjustable lighting and USB charging capabilities, powered by batteries with a six-hour charge capacity. The company employs a monthly payment model to minimize financial barriers for customers, ensuring access to modern energy solutions while incorporating maintenance and battery replacement services. By fostering trust within local communities, Oolu strives to enhance energy access and improve the quality of life for its users.

Varda Space Industries, Inc. is a space manufacturing startup based in San Francisco, California, founded in 2020 by Delian Asparouhov and Trae Stephens. The company specializes in creating products in space that are intended for terrestrial applications, leveraging the unique advantages of low gravity. Varda aims to establish an infrastructure for harvesting materials from asteroids, enabling the production of new products in space. This approach not only facilitates the manufacturing of innovative goods but also promotes sustainability by reducing reliance on the destructive extraction of Earth's resources.

Kenota Health specializes in the development of advanced diagnostic tools for allergy testing in humans. The company's innovative point-of-care system allows for the collection of small blood samples, which are analyzed using streamlined equipment to quickly determine allergen sensitization. This process delivers immediate test results, enabling physicians to obtain quality diagnostic information efficiently. By offering a safe, simple, and cost-effective alternative to traditional allergy testing methods, Kenota Health aims to enhance patient outcomes and streamline the diagnostic process in clinical settings.

Deepcell, Inc. is a biotechnology company based in Mountain View, California, that specializes in providing advanced diagnostic solutions through its innovative microfluidic imaging platform. Founded in 2015, the company focuses on delivering non-invasive tests with diagnostic-level accuracy, enabling researchers and clinicians to gain insights at the single-cell level. Deepcell's technology employs artificial intelligence to analyze and classify cells based on their morphological features, isolating viable cells for various applications in translational research, diagnostic testing, and therapeutics. By utilizing ordinary blood samples, Deepcell enhances the understanding of genetic health without the need for invasive procedures, thereby improving the diagnosis and treatment of diseases.

64x Bio develops a platform aimed at accelerating the discovery and optimization of mammalian cell lines for biomanufacturing and therapeutics. The company employs a high-throughput discovery and screening approach combined with an integrated computational design loop to create genetically engineered cell lines tailored for the production of viral vectors. This focus is particularly relevant for cell and gene therapies, as it enhances the efficiency of viral vector production. By providing purpose-built cell lines, 64x Bio enables pharmaceutical and biotechnology companies to improve their manufacturing capacity and reduce costs, ultimately facilitating the timely delivery of innovative therapies to patients.

Zero Acre Farms is a food company focused on eliminating the reliance on harmful vegetable oils in the food industry. It offers a sustainable alternative produced through fermentation technology, utilizing microorganisms to create oils and fats that contain significantly lower levels of unhealthy fats associated with inflammation and disease. This innovative approach aims to promote healthier dietary options for consumers while addressing the environmental concerns linked to traditional oil production.

Brightseed, Inc. is a biotechnology company based in San Francisco, California, that specializes in the discovery of bioactive compounds in plants to enhance human health. Utilizing its advanced Forager platform, which employs artificial intelligence and machine learning algorithms, Brightseed accelerates the identification and validation of clinically beneficial molecules. This innovative approach enables the company to uncover connections between natural compounds and health outcomes, revealing the potential of bioactives that have previously remained uncharted. By integrating these discoveries back into the food supply chain, Brightseed collaborates with various companies across the consumer health continuum to develop science-backed health solutions aimed at managing chronic diseases and improving overall quality of life. Founded in 2017, Brightseed is committed to exploring the untapped resources of the plant kingdom to address pressing health challenges.

Manifold Biotechnologies, Inc. is a biotechnology company that specializes in developing platforms for the pharmacological measurement of various therapeutic protein variants. By integrating DNA technologies with machine learning, the company aims to create protein drugs that address challenging diseases. Manifold Bio's innovative approach includes a protein barcoding platform designed to enable multiplexed quantitation of protein therapeutics, thereby generating extensive data that enhances the drug development process. Founded in 2019 and located in Allston, Massachusetts, the company is focused on advancing measurement-driven design in the field of protein therapeutics.

Ukama is a company based in Pleasanton, California, that specializes in providing hardware and software solutions for building and managing LTE-based cellular networks. It enables enterprises, internet service providers, community networks, and individuals to create custom cellular network solutions tailored to their specific needs. By offering a modern technology stack, Ukama aims to help clients reduce network costs, enhance security, and improve accessibility for on-campus users. Its services facilitate the easy setup, deployment, and operation of cellular networks, catering to a wide range of users seeking reliable connectivity solutions.

Meati Foods is a Boulder, Colorado-based company specializing in the production and sale of fungi-based meat alternatives. Founded in 2016, the company aims to provide sustainable and nutritious plant-based options that serve as an alternative to traditional meat products. Meati Foods utilizes a proprietary fermentation process to create minimally processed steaks made from natural ingredients, ensuring its offerings are free from common allergens. The company markets its products online, making them accessible to a wide audience seeking vegan food choices that are both healthy and environmentally friendly.

Rad AI, Inc. is a company based in Berkeley, California, that specializes in developing an artificial intelligence platform designed to automate report generation for radiologists. Founded in 2018, Rad AI's solution streamlines the radiology workflow by automating repetitive tasks, thereby enhancing efficiency and accuracy while addressing issues of clinician burnout. The platform utilizes AI to generate report impressions, allowing radiologists to dictate findings using voice recognition technology, identify errors, and customize recommendations. By integrating smoothly with existing workflows, Rad AI aims to improve patient care and support radiologists in delivering accurate and timely reports.

Cover is a technology company that specializes in creating custom Backyard Studios and guesthouses as energy-efficient housing alternatives. The company employs proprietary design software to assess property specifications, facilitating a streamlined process that encompasses design, permitting, manufacturing, and installation. By utilizing a precision manufactured building system, Cover aims to deliver high-quality designs and functional spaces in significantly less time compared to traditional construction methods. Initially launched in Los Angeles, the company is now accepting pre-orders on a global scale, reflecting its commitment to making well-designed living spaces accessible to a broader audience.

Geltor, Inc. is a biodesign company based in San Leandro, California, that specializes in producing bioactive, animal-free collagens and proteins for various applications in beauty, nutrition, and wellness. Established in 2015, Geltor offers innovative products such as Collume, which promotes skincare cellular regeneration and dermal synthesis, and HumaColl21, which enhances skin health by boosting collagen and elastin levels. Additionally, the company provides vegan collagen peptides and other novel proteins designed for functional food and nutraceutical formulations. Geltor's products are sustainably cultivated and clinically validated, allowing businesses to create effective, plant-based solutions that contribute to a more sustainable future.

Ansa Biotechnologies, Inc. is a biotechnology company based in Berkeley, California, focused on developing innovative DNA synthesis technology utilizing enzymes. Established in 2018, the company aims to improve upon traditional chemical methods of DNA synthesis that have remained largely unchanged for decades. Ansa's enzymatic approach offers significant advantages, including increased speed, accuracy, and cleanliness in the production of DNA fragments such as oligonucleotides. This technology enhances the capabilities of biological research, therapeutics, diagnostics, and biomanufacturing by enabling the synthesis of gene-length oligonucleotides. Through its advancements, Ansa Biotechnologies seeks to facilitate innovation in the fields of biological research and engineering, ultimately providing valuable services to medical researchers and contributing to the broader biotechnology landscape.

Octant Bio is a biotechnology company focused on developing synthetic technology aimed at enhancing health and treating diseases. The company employs a platform that integrates synthetic biology, genome engineering, next-generation sequencing, and computational tools to measure the activity of thousands of receptor pathways in human cells. This advanced technology allows scientists to utilize machine learning techniques to engineer small molecules capable of interacting with multiple receptors, thereby creating new possibilities for the treatment of complex diseases.

Manifold Biotechnologies, Inc. is a biotechnology company that specializes in developing platforms for the pharmacological measurement of various therapeutic protein variants. By integrating DNA technologies with machine learning, the company aims to create protein drugs that address challenging diseases. Manifold Bio's innovative approach includes a protein barcoding platform designed to enable multiplexed quantitation of protein therapeutics, thereby generating extensive data that enhances the drug development process. Founded in 2019 and located in Allston, Massachusetts, the company is focused on advancing measurement-driven design in the field of protein therapeutics.

54gene is a healthcare company founded in 2019 by Dr. Abasi Ene-Obong, focused on advancing genomic research in Africa. Headquartered in San Francisco with an office in Lagos, Nigeria, the company aims to address the underrepresentation of African genetic data in pharmaceutical research, where only 2% of genetic material used is from African populations. By developing a pan-African biobank, 54gene seeks to identify new drug targets and create diagnostics and treatments for various diseases, including cancer, cardiovascular, and neurodegenerative diseases. Additionally, the company offers genetic testing and molecular diagnostics services to enhance understanding of the human genome and improve access to essential healthcare solutions.

Rebellyous Foods is a Seattle-based company founded in 2017 that specializes in producing plant-based meat alternatives, including chicken nuggets, patties, and strips. The company aims to make meat alternatives more accessible and affordable by implementing innovative food manufacturing technologies and processes designed for large-scale production. By utilizing high-throughput automation and energy-efficient manufacturing tools, Rebellyous Foods seeks to achieve price parity with traditional animal-based meats. Its products are primarily targeted at the food service market, including schools, hospitals, corporate cafeterias, and restaurants, providing customers with protein-rich options that can replace animal-based meat on a broad scale.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Microverse is an online educational platform focused on training remote software developers. The organization aims to connect one million individuals with remote job opportunities by 2030. Its educational model emphasizes collaborative learning, where students from diverse backgrounds work in small, distributed teams and engage in pair programming. Through this approach, they hold each other accountable while developing their coding skills on open source and freelance projects. Microverse's programs are structured around income share agreements, allowing students to learn full-stack web development and receive career guidance. This model not only equips students with the necessary technical skills but also enables companies to recruit talented software developers without geographic limitations.

BillionToOne Inc. is a precision diagnostics company based in Menlo Park, California, that specializes in molecular testing for prenatal and oncology applications. Established in 2016, the company has developed a patented molecular counter platform capable of detecting and quantifying DNA molecules at an extraordinarily precise level. BillionToOne's flagship product, UNITY, is a noninvasive prenatal screening test that analyzes fetal cell-free DNA from a simple blood sample taken from the mother, allowing for the detection of single-gene disorders such as cystic fibrosis, spinal muscular atrophy, and beta-thalassemia. This innovative approach aims to replace more invasive procedures like amniocentesis, providing a safer and more affordable alternative for expecting mothers, particularly in developing countries. Additionally, the company is focused on oncology, offering tests that can accurately identify actionable mutations and assess tumor burden through blood samples.

Astranis is a satellite technology developer focused on providing high-speed internet access to underserved regions. The company aims to address the digital divide by launching satellites that can transmit data to specific terrestrial locations, facilitating internet connectivity for the estimated 4 billion people worldwide who currently lack access. By offering reliable internet services at significantly lower costs than traditional methods, Astranis enables governments and businesses to connect communities and expand internet access globally.

Advano, also known as NanoStar, Inc., is a New Orleans-based company that specializes in silicon nanotechnology, focusing on the development of advanced silicon anode materials for lithium-ion batteries. Founded in 2014 and a graduate of Y Combinator in 2017, Advano offers scalable solutions that enhance the energy density and longevity of lithium-ion batteries by integrating or replacing traditional graphite components. Its innovative products cater to various industries, including electric vehicles and consumer electronics, and are designed to improve energy storage and charging capabilities. By providing low-cost, high-performance materials, Advano aims to support the domestic battery supply chain and facilitate the transition to sustainable energy solutions.

UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

Arpeggio Bio, established in 2017 and headquartered in Boulder, Colorado, specializes in developing innovative software that captures snapshots of cellular RNA activity. By combining biological assays with advanced machine learning algorithms, the company enables pharmaceutical and biotechnology firms to understand a drug's mechanism of action at low sequencing depths. Arpeggio Bio's technology reveals intricate biological networks, facilitating more informed therapeutic development.

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Antora Energy specializes in providing zero-carbon industrial heat and power solutions for heavy industries, offering a more reliable alternative to fossil fuels. The company develops innovative thermal batteries that utilize excess solar and wind electricity to heat blocks of carbon, creating a sustainable energy source. These thermal energy storage systems effectively convert heat energy into electric energy, facilitating the electrification of heavy industry. By enabling the integration of renewable resources into the electricity grid, Antora Energy aims to deliver convenient, sustainable, and reliable electricity while significantly reducing carbon emissions on a global scale.

Lively, Inc. is a health savings account (HSA) platform designed for both employers and individuals. Founded in 2016 and based in San Francisco, California, Lively offers a user-centric solution that enhances the experience of managing HSAs. The platform aims to help consumers optimize their healthcare spending, maximize savings, and improve their overall well-being. By providing an intuitive interface, Lively facilitates easier access to HSA-compatible plans, making healthcare management more straightforward for users.

Brave Care, Inc. specializes in urgent pediatric health care services, treating a wide range of conditions, including allergies, asthma, cough, ear pain, eye issues, fever, minor fractures, and rashes. The company also offers pediatric-specific laboratory services, on-site x-ray, and light sedation for certain procedures. Founded in 2019 and based in Portland, Oregon, Brave Care operates clinics exclusively designed for children in Oregon and Texas. In addition to in-person care, the BraveCare.com website and mobile app provide nationwide pediatric advice to assist parents in supporting their children's health and development.

Earth AI, established in 2016 and headquartered in Parramatta, Australia, specializes in AI-driven mineral exploration. It uses satellite, geophysical, and geochemical data to generate precise geological maps and suggest locations for mineral exposure, particularly for metals like copper, lead, zinc, nickel, cobalt, vanadium, and rare earth elements. By doing so, Earth AI helps mining explorers enhance their discovery prospects while reducing operational risks and costs.