Innovation Works

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

CapSen Robotics develops advanced computer vision systems that enable machines to comprehend and navigate cluttered environments. Their core technology, derived from MIT research on 3D object detection, empowers robots and automation systems in various industries such as manufacturing, logistics, and retail inventory management.

Gridwise develops a mobile application for gig economy drivers, empowering them with real-time insights to maximize earnings. Its platform offers demand alerts, passenger data tracking, mileage logging, tax deduction calculation, and performance reporting.

Plexision develops cellular biomarkers and personalized diagnostic tests for immunological disorders and solid organ transplantation. Its Pleximmune blood test predicts transplant rejection by measuring antigen-specific white blood cells, supported by patent-pending technology. The company operates a CLIA-certified central laboratory in Pittsburgh providing testing services for transplant recipients and drug developers. Its platform enables assessment of disease risk, prediction of drug efficacy for individual patients, and guidance on dosing for novel immunological therapies, with capabilities including rapid six-hour panels for conditions such as CMV infection and transplant rejection, and a focus on pediatric liver and intestine transplant patients.

Honeycomb Credit operates an online platform facilitating debt crowdfunding between small business owners and their communities or investors. Incorporated in 2017, the company is headquartered in Pittsburgh, Pennsylvania.

Toyz Electronics specializes in developing educational technology solutions. It offers a gamified learning platform that teaches STEAM subjects, entrepreneurship, and storytelling through a unique superhero rap concept. The platform's culturally relevant curriculum combines hip-hop culture, music, gaming, 3D models, comics, and design to engage students and help them develop technical and soft skills.

Founded in 1994, PittMoss manufactures peat-free potting mixtures using recycled paper fibers. Its primary products are PittMoss and PittMoss Prime, serving commercial greenhouse growers, nurseries, and home gardeners in the United States.

Workers First is a research and design company founded in 2016 and headquartered in Pittsburgh, Pennsylvania. The company specializes in developing innovative polymer materials that enhance worker protection, particularly in hazardous environments. Its patented polymer technology is designed to neutralize acids on contact, making it suitable for use in personal protective equipment and acid-proof linings. This advancement enables workers to perform their jobs safely and effectively in situations where they are exposed to corrosive substances, thereby improving overall safety and productivity in the workplace.

Subtl Beauty, Inc. is a cosmetics brand founded in 2018 and based in Pittsburgh, Pennsylvania. The company specializes in the production of stackable makeup products designed for contemporary women seeking convenience and flexibility in their beauty routines. Its unique packaging allows for modular, customizable stacks that can easily fit in a gym bag, purse, or back pocket, making them ideal for on-the-go lifestyles. Subtl Beauty's product offerings are crafted for efficiency, easy application, and long-lasting wear, aligning with the values of conscious consumers by being clean, vegan, cruelty-free, paraben-free, and fragrance-free. The company's online sales platform further enhances accessibility for customers seeking innovative, travel-friendly makeup solutions.

ExchangeLodge is a financial technology company that develops and operates a platform for private capital data management, automation, and data integration. The platform provides a playbook of mission-critical workflows, enterprise data connectors, and boardroom-quality reports, enabling users to design and manage reporting across multiple data sources. It records tasks and subtasks, assigns them to teams and individuals, and tracks progress to support governance and collaboration. The software automates manual data processes, cleanses data with sophisticated business rules, and powers data workflows by integrating existing systems to improve data quality and completeness. It supports investor and regulatory reporting and helps mitigate data and key-person risk. With a focus on private markets, the company serves FinTech and RegTech contexts and aims to help clients scale with accuracy and efficiency. Based in Pittsburgh and established in 2015, the company delivers solutions that align data across systems for better decision-making.

Founded in 2020, Phlux Technologies specializes in developing innovative 3D sensor technology for robotics and automation. Its products enhance safety and efficiency by enabling robots to navigate effectively, protecting workers from hazards, and detecting obstacles.

UpContent develops a SaaS platform that discovers brand mentions and curates digital content from various sources like news articles, blogs, and social media. Its tool automates the content discovery process, allowing users to engage audiences effectively. Founded in 2015, UpContent is headquartered in Pittsburgh, Pennsylvania.

EKTO VR is a Pittsburgh-based developer of wearable locomotion technology for virtual reality, including a motorized device called Traverse and wearable robotic boots. The devices use rotating plates and wheels to simulate walking in VR, enabling users to move in a defined space while remaining in place, which helps reduce motion sickness. The technology aims to enhance the realism of training simulations and immersive VR experiences for users around the world.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

DisSolves Inc. is a Pittsburgh-based company specializing in the development and manufacture of dissolvable packaging materials for the food industry. Founded in 2016, DisSolves creates innovative, edible packaging made from natural and plant-based ingredients, specifically designed for single servings of drink mixes such as protein powder and flavor enhancers. Their flagship product, a pod, replaces traditional non-recyclable packaging with a more convenient, environmentally friendly option. DisSolves is committed to sustainability, utilizing renewable and vegan materials such as seaweed and polysaccharides to ensure their packaging is both degradable and safe for consumption. The company aims to enhance consumer convenience while promoting health and environmental responsibility, addressing the growing demand for efficient and eco-friendly food packaging solutions.

Adrich is a Pittsburgh-based company that develops a consumer insights platform consisting of smart packaging hardware and customized software. The platform autonomously collects and transmits product usage data via product labels, capturing day and time, geolocation, and volumetric usage in real time. This data helps brands and retailers understand trends, behaviors, and usage patterns, supporting post-purchase engagement, retention, and targeted service.

Ariel Precision Medicine, Inc. is an integrated genomics and digital health company focused on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases and disorders. Founded in 2015 and headquartered in Pittsburgh, Pennsylvania, the company develops innovative clinical decision support tools aimed at simplifying personalized treatment in both emergency departments and clinical settings. One of its key offerings is ArielDx, a cloud-based tool designed to enhance the diagnosis and treatment of pancreatic disease, thereby improving patient outcomes through tailored healthcare solutions.

Apollo Neuroscience, Inc. is a Pittsburgh-based company that manufactures a clinically validated wearable wellness device designed to assist the body in recovering from chronic stress through gentle vibrations. Established in 2016, the company also offers an application that integrates neuroscience and machine learning to enhance heart rate variability, promoting improved routines for waking, focusing, unwinding, and engaging the parasympathetic nervous system. The product is marketed directly to consumers through online sales and is positioned as a wellness solution rather than a treatment for psychiatric disorders.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Make It Home Safe is a mobile application founded in 2017 and headquartered in Pittsburgh, Pennsylvania, that focuses on enhancing safety and security during traffic stops. The app serves as a tool for both motorists and law enforcement, providing real-time identity verification to facilitate smoother interactions. By aiming to reduce tensions between police and the public, Make It Home Safe seeks to create a safer environment on the road, helping to assure users that their safety is prioritized during potentially stressful encounters.

Optimus Technologies is a clean energy technology company headquartered in Pittsburgh, Pennsylvania. It specializes in developing advanced fuel management systems that enable medium and heavy-duty truck fleets to operate on 100% biodiesel. The company's flagship product, the Vector System, integrates seamlessly into existing diesel engines without the need for extensive modifications or replacements. This technology allows fleet operators to achieve significant reductions in fuel costs and emissions while effectively meeting renewable fuel targets. By providing a practical solution for transitioning to low-carbon fuels, Optimus Technologies addresses the challenges of emissions reductions in heavy-duty applications.

SpIntellx, Inc. is a computational and systems pathology company based in Pittsburgh, Pennsylvania, that specializes in spatial intelligence software products designed for analyzing pathology tissue sections in cancer diagnosis. Founded in 2017, the company offers innovative solutions such as SpIntellx, which processes image data sets from various imaging platforms and reagents, and HistoMapr, a computational guide for pathologists. Additionally, TumorMapr is utilized to analyze the spatial interactions of biomarkers within whole slide images using multiplexed fluorescence. With a focus on Precision Pathology and Spatially Intelligent Biology, SpIntellx leverages unbiased spatial analytics powered by explainable AI to enhance understanding of complex cancer biology, thereby facilitating advancements in drug development, diagnostics, and treatment strategies.

Toyz Electronics specializes in developing educational technology solutions. It offers a gamified learning platform that teaches STEAM subjects, entrepreneurship, and storytelling through a unique superhero rap concept. The platform's culturally relevant curriculum combines hip-hop culture, music, gaming, 3D models, comics, and design to engage students and help them develop technical and soft skills.

Honeycomb Credit operates an online platform facilitating debt crowdfunding between small business owners and their communities or investors. Incorporated in 2017, the company is headquartered in Pittsburgh, Pennsylvania.

Founded in 2009, Setex Technologies is a Pittsburgh-based manufacturer specializing in dry adhesive technology inspired by gecko feet. They offer micro-fibrillar polymer gripping surfaces for various products, serving both consumers and manufacturers.

PECA Labs is a Pittsburgh-based medical device company spun out of Carnegie Mellon University and UPMC that develops polymeric heart valves and vascular grafts for pediatric congenital heart disease. Its lead product, the MASA Valve, is a synthetic valved conduit intended for pediatric right ventricular outflow tract reconstruction, leveraging ePTFE material properties and radiopaque markings to improve durability and intraoperative configurability. The company also offers exGraft, an ePTFE vascular graft with radiopaque markers. PECA Labs focuses on orphan patient populations and aims to reduce the need for multiple surgeries in children, with the MASA Valve designed to address limitations of existing conduits. The MASA Valve has received FDA Humanitarian Use Device designation, and early intraoperative implants have demonstrated reduced re-operation rates compared with alternatives. Headquartered in Pittsburgh since its founding around 2011-2012, PECA Labs pursues pediatric cardiovascular solutions with an emphasis on improving long-term outcomes for congenital heart disease patients.

Inspired Cognition is a Pennsylvania-based company that specializes in developing artificial intelligence software tailored for the research and development lifecycle. The company focuses on creating digital tools and online systems that assist businesses in integrating AI solutions effectively. Its products provide evaluation as a service, enabling organizations to monitor, analyze, and improve their operational plans. Additionally, Inspired Cognition’s offerings include data modeling capabilities that help business professionals identify system pain points and propose actionable solutions. Through its innovations, Inspired Cognition aims to support businesses in leveraging AI to enhance their operations and decision-making processes.

UpContent develops a SaaS platform that discovers brand mentions and curates digital content from various sources like news articles, blogs, and social media. Its tool automates the content discovery process, allowing users to engage audiences effectively. Founded in 2015, UpContent is headquartered in Pittsburgh, Pennsylvania.

Optimus Technologies is a clean energy technology company headquartered in Pittsburgh, Pennsylvania. It specializes in developing advanced fuel management systems that enable medium and heavy-duty truck fleets to operate on 100% biodiesel. The company's flagship product, the Vector System, integrates seamlessly into existing diesel engines without the need for extensive modifications or replacements. This technology allows fleet operators to achieve significant reductions in fuel costs and emissions while effectively meeting renewable fuel targets. By providing a practical solution for transitioning to low-carbon fuels, Optimus Technologies addresses the challenges of emissions reductions in heavy-duty applications.

DisSolves Inc. is a Pittsburgh-based company specializing in the development and manufacture of dissolvable packaging materials for the food industry. Founded in 2016, DisSolves creates innovative, edible packaging made from natural and plant-based ingredients, specifically designed for single servings of drink mixes such as protein powder and flavor enhancers. Their flagship product, a pod, replaces traditional non-recyclable packaging with a more convenient, environmentally friendly option. DisSolves is committed to sustainability, utilizing renewable and vegan materials such as seaweed and polysaccharides to ensure their packaging is both degradable and safe for consumption. The company aims to enhance consumer convenience while promoting health and environmental responsibility, addressing the growing demand for efficient and eco-friendly food packaging solutions.

Subtl Beauty, Inc. is a cosmetics brand founded in 2018 and based in Pittsburgh, Pennsylvania. The company specializes in the production of stackable makeup products designed for contemporary women seeking convenience and flexibility in their beauty routines. Its unique packaging allows for modular, customizable stacks that can easily fit in a gym bag, purse, or back pocket, making them ideal for on-the-go lifestyles. Subtl Beauty's product offerings are crafted for efficiency, easy application, and long-lasting wear, aligning with the values of conscious consumers by being clean, vegan, cruelty-free, paraben-free, and fragrance-free. The company's online sales platform further enhances accessibility for customers seeking innovative, travel-friendly makeup solutions.

Honeycomb Credit operates an online platform facilitating debt crowdfunding between small business owners and their communities or investors. Incorporated in 2017, the company is headquartered in Pittsburgh, Pennsylvania.

Arieca LLC, founded in 2018 and based in Pittsburgh, Pennsylvania, specializes in the development and distribution of Thubber, a thermally conductive rubber composite. This innovative material merges the compliance and elasticity of soft silicone rubber with the thermal conductivity of metal, making it suitable for various applications such as circuit wiring, sensors, and passive heat exchangers. Arieca's product addresses heat management challenges in the electronics industry, enhancing performance while ensuring safe interactions between devices and users. By providing an alternative to traditional rubber, Arieca aims to improve the efficiency of electronic components across multiple sectors.

SpIntellx, Inc. is a computational and systems pathology company based in Pittsburgh, Pennsylvania, that specializes in spatial intelligence software products designed for analyzing pathology tissue sections in cancer diagnosis. Founded in 2017, the company offers innovative solutions such as SpIntellx, which processes image data sets from various imaging platforms and reagents, and HistoMapr, a computational guide for pathologists. Additionally, TumorMapr is utilized to analyze the spatial interactions of biomarkers within whole slide images using multiplexed fluorescence. With a focus on Precision Pathology and Spatially Intelligent Biology, SpIntellx leverages unbiased spatial analytics powered by explainable AI to enhance understanding of complex cancer biology, thereby facilitating advancements in drug development, diagnostics, and treatment strategies.

CapSen Robotics develops advanced computer vision systems that enable machines to comprehend and navigate cluttered environments. Their core technology, derived from MIT research on 3D object detection, empowers robots and automation systems in various industries such as manufacturing, logistics, and retail inventory management.

Touchwood Labs, Inc. is an innovative company based in Pittsburgh, Pennsylvania, founded in 2019. The company specializes in developing technology for office and home furniture, focusing on creating interactive and screenless interfaces. Its proprietary invisible displays can be embedded beneath the surface of various materials, such as wood or plastic, allowing them to remain hidden until activated. This technology enables users to interact with multiple IoT-connected devices through seamless visual experiences, enhancing the way individuals engage with their environment. Touchwood Labs aims to revolutionize technology interactions by combining mindful design with advanced hardware, thereby fostering healthier relationships with technology in everyday settings.

Civic Champs, Inc. is a technology company that specializes in developing a mobile-based platform for nonprofit organizations to streamline volunteer management. Founded in 2019 and headquartered in Bloomington, Indiana, with an additional office in Pittsburgh, Pennsylvania, Civic Champs offers an application that utilizes geofencing technology to monitor volunteer activities by automatically tracking when a volunteer's mobile device enters or exits designated areas. The platform facilitates essential functions such as hour tracking, scheduling, engagement, and analytical insights, enabling nonprofits to efficiently manage volunteer hours while reducing manual data entry. Additionally, it allows for small donations and provides real-time data access, mentorship tracking, and compliance features. Civic Champs aims to enhance volunteer engagement and help nonprofits maximize their impact by simplifying administrative processes. The application is available for download on both the App Store and Google Play.

Founded in 2020, Phlux Technologies specializes in developing innovative 3D sensor technology for robotics and automation. Its products enhance safety and efficiency by enabling robots to navigate effectively, protecting workers from hazards, and detecting obstacles.

Founded in 2018, Naima Health is a Pittsburgh-based company that develops health tools using behavioral decision science and machine learning. Their platform engages patients, particularly pregnant women at high risk, in their clinical care by providing personalized, engaging pregnancy risk assessments and support.

Creegh Pharmaceuticals specializes in the pharmaceutical preparation industry. It was founded in 2018 and headquartered in Pittsburgh, Pennsylvania.

ESTAT Actuation is a company founded in 2019 and based in Pittsburgh, Pennsylvania, that specializes in the development of electroadhesive clutches. These innovative clutches are designed to enhance the performance of robots and machinery by reducing the size and cost of actuators. By providing engineers with lightweight and low-power actuation hardware, ESTAT Actuation enables clients to improve the capabilities and affordability of their robotic systems and machines.

CytoAgents is a clinical-stage biotechnology company focused on developing innovative pharmaceutical products for treating life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation.

Touchwood Labs, Inc. is an innovative company based in Pittsburgh, Pennsylvania, founded in 2019. The company specializes in developing technology for office and home furniture, focusing on creating interactive and screenless interfaces. Its proprietary invisible displays can be embedded beneath the surface of various materials, such as wood or plastic, allowing them to remain hidden until activated. This technology enables users to interact with multiple IoT-connected devices through seamless visual experiences, enhancing the way individuals engage with their environment. Touchwood Labs aims to revolutionize technology interactions by combining mindful design with advanced hardware, thereby fostering healthier relationships with technology in everyday settings.

PECA Labs is a Pittsburgh-based medical device company spun out of Carnegie Mellon University and UPMC that develops polymeric heart valves and vascular grafts for pediatric congenital heart disease. Its lead product, the MASA Valve, is a synthetic valved conduit intended for pediatric right ventricular outflow tract reconstruction, leveraging ePTFE material properties and radiopaque markings to improve durability and intraoperative configurability. The company also offers exGraft, an ePTFE vascular graft with radiopaque markers. PECA Labs focuses on orphan patient populations and aims to reduce the need for multiple surgeries in children, with the MASA Valve designed to address limitations of existing conduits. The MASA Valve has received FDA Humanitarian Use Device designation, and early intraoperative implants have demonstrated reduced re-operation rates compared with alternatives. Headquartered in Pittsburgh since its founding around 2011-2012, PECA Labs pursues pediatric cardiovascular solutions with an emphasis on improving long-term outcomes for congenital heart disease patients.

Ariel Precision Medicine, Inc. is an integrated genomics and digital health company focused on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases and disorders. Founded in 2015 and headquartered in Pittsburgh, Pennsylvania, the company develops innovative clinical decision support tools aimed at simplifying personalized treatment in both emergency departments and clinical settings. One of its key offerings is ArielDx, a cloud-based tool designed to enhance the diagnosis and treatment of pancreatic disease, thereby improving patient outcomes through tailored healthcare solutions.

Gridwise develops a mobile application for gig economy drivers, empowering them with real-time insights to maximize earnings. Its platform offers demand alerts, passenger data tracking, mileage logging, tax deduction calculation, and performance reporting.

Make It Home Safe is a mobile application founded in 2017 and headquartered in Pittsburgh, Pennsylvania, that focuses on enhancing safety and security during traffic stops. The app serves as a tool for both motorists and law enforcement, providing real-time identity verification to facilitate smoother interactions. By aiming to reduce tensions between police and the public, Make It Home Safe seeks to create a safer environment on the road, helping to assure users that their safety is prioritized during potentially stressful encounters.

Apollo Neuroscience, Inc. is a Pittsburgh-based company that manufactures a clinically validated wearable wellness device designed to assist the body in recovering from chronic stress through gentle vibrations. Established in 2016, the company also offers an application that integrates neuroscience and machine learning to enhance heart rate variability, promoting improved routines for waking, focusing, unwinding, and engaging the parasympathetic nervous system. The product is marketed directly to consumers through online sales and is positioned as a wellness solution rather than a treatment for psychiatric disorders.

Founded in 2020, Phlux Technologies specializes in developing innovative 3D sensor technology for robotics and automation. Its products enhance safety and efficiency by enabling robots to navigate effectively, protecting workers from hazards, and detecting obstacles.

Subtl Beauty, Inc. is a cosmetics brand founded in 2018 and based in Pittsburgh, Pennsylvania. The company specializes in the production of stackable makeup products designed for contemporary women seeking convenience and flexibility in their beauty routines. Its unique packaging allows for modular, customizable stacks that can easily fit in a gym bag, purse, or back pocket, making them ideal for on-the-go lifestyles. Subtl Beauty's product offerings are crafted for efficiency, easy application, and long-lasting wear, aligning with the values of conscious consumers by being clean, vegan, cruelty-free, paraben-free, and fragrance-free. The company's online sales platform further enhances accessibility for customers seeking innovative, travel-friendly makeup solutions.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

SpIntellx, Inc. is a computational and systems pathology company based in Pittsburgh, Pennsylvania, that specializes in spatial intelligence software products designed for analyzing pathology tissue sections in cancer diagnosis. Founded in 2017, the company offers innovative solutions such as SpIntellx, which processes image data sets from various imaging platforms and reagents, and HistoMapr, a computational guide for pathologists. Additionally, TumorMapr is utilized to analyze the spatial interactions of biomarkers within whole slide images using multiplexed fluorescence. With a focus on Precision Pathology and Spatially Intelligent Biology, SpIntellx leverages unbiased spatial analytics powered by explainable AI to enhance understanding of complex cancer biology, thereby facilitating advancements in drug development, diagnostics, and treatment strategies.

Civic Champs, Inc. is a technology company that specializes in developing a mobile-based platform for nonprofit organizations to streamline volunteer management. Founded in 2019 and headquartered in Bloomington, Indiana, with an additional office in Pittsburgh, Pennsylvania, Civic Champs offers an application that utilizes geofencing technology to monitor volunteer activities by automatically tracking when a volunteer's mobile device enters or exits designated areas. The platform facilitates essential functions such as hour tracking, scheduling, engagement, and analytical insights, enabling nonprofits to efficiently manage volunteer hours while reducing manual data entry. Additionally, it allows for small donations and provides real-time data access, mentorship tracking, and compliance features. Civic Champs aims to enhance volunteer engagement and help nonprofits maximize their impact by simplifying administrative processes. The application is available for download on both the App Store and Google Play.

CytoAgents is a clinical-stage biotechnology company focused on developing innovative pharmaceutical products for treating life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation.

SovaSage is a digital healthcare platform used to come up with the treatment of sleep apnea patients and other chronic conditions. It was founded in 2020 and is headquartered in Pittsburgh, Pennsylvania.

Founded in 2009 and headquartered in Pittsburgh, Pennsylvania, Encentiv Energy operates a platform that facilitates participation in energy efficiency programs. It offers Encentivizer, a national incentive management tool connecting utilities, vendors, finance companies, and customers to maximize rebates and incentives for new construction and renovation projects. The company also provides energy advisory services and project financing.

ESTAT Actuation is a company founded in 2019 and based in Pittsburgh, Pennsylvania, that specializes in the development of electroadhesive clutches. These innovative clutches are designed to enhance the performance of robots and machinery by reducing the size and cost of actuators. By providing engineers with lightweight and low-power actuation hardware, ESTAT Actuation enables clients to improve the capabilities and affordability of their robotic systems and machines.

CareGoGi operates a platform that connects users with local caregivers for senior home care. Launched in 2016, it enables users to browse caregiver profiles, interview them, and hire based on availability and hourly rates.

Identified Technologies Corporation specializes in self-piloting aerial mapping and land survey drones, providing comprehensive data scanning, capture, access, and analytics solutions. Founded in 2013 and headquartered in Pittsburgh, Pennsylvania, the company develops technologies that enhance project visibility and team productivity across various industries, including energy, mining, manufacturing, and construction. Its offerings include advanced features such as 3-D volumetric analysis, 2-D distance measurement, contour line mapping, and digital surface models. The platform also facilitates job site tracking, as-built versus as planned comparisons, and progress forecasting, enabling businesses to improve project monitoring and profitability.

Gridfruit is a provider of a data-driven intelligence to food operations. Its artificial intelligence-based learning platform utilizes existing food data to reduce energy and maintenance costs for food businesses. The companty was established in Pittsburgh, Pennsylvania in 2018.

Rapid Flow Technologies spun out of Carnegie Mellon University with the goal of introducing new Intelligent Transportation Systems (ITS) technologies into the marketplace. Rapid Flow was created to commercialize the Surtrac adaptive traffic signal control technology developed in the Robotics Institute at Carnegie Mellon as part of the Traffic21 research initiative. The company’s founders include the original inventors of Surtrac, who have successfully expanded the initial pilot deployment of Surtrac in Pittsburgh to a network of 50 intersections over the past three years. Rapid Flow holds an exclusive license to the patented Surtrac technology from Carnegie Mellon University, and the University has a stake in the company. In addition to Surtrac, Rapid Flow is also engaged in the development of ubiquitous Bluetooth AVI sensor network technology for ITS performance modeling and other applications through a Small Business Innovation Research (SBIR) grant from the U.S. Department of Transportation.

CompleteBankData, developed by Red River Research, is a banking information platform that specializes in providing comprehensive financial data on unlisted stocks and private companies. Based in Pittsburgh, Pennsylvania, the company offers a suite of tools designed to assist banks in strategy development and lead generation. Its platform delivers access to regulatory financials and analytics, along with market intelligence, empowering financial institutions to identify market opportunities and gain valuable insights. CompleteBankData's proprietary investment research and extensive datasets serve as essential resources for banks looking to enhance their lending capabilities and make informed decisions in a competitive landscape.

Interphase Materials, established in 2015 and headquartered in Pittsburgh, Pennsylvania, specializes in developing advanced surface treatment technologies. The company's primary focus is to enhance the efficiency of industrial cooling systems, serving a diverse range of clients including power plants, commercial and industrial HVAC systems, international heat exchanger manufacturers, and the U.S. Navy. Interphase's signature Heat Transfer Enhancement (HTE) system has demonstrated the potential to increase heat exchanger efficiency by 5-10% in initial tests, thereby reducing maintenance costs and improving overall system performance.

Founded in Pittsburgh, Pennsylvania in 2016, Nollapelli is a manufacturer of bedding products. It specializes in bed sheets and pillowcases designed with wellness-focused textiles to balance moisture, temperature, and friction for a healthier sleep experience.

Women's Job Search Network, LLC is a job-search platform designed to support female job seekers in their employment journeys. Established in 2018 and headquartered in McMurray, Pennsylvania, the company aims to empower women by providing the resources and tools necessary to navigate the job market with confidence. By focusing on the unique challenges faced by women in their job searches, Women's Job Search Network strives to facilitate meaningful connections between female candidates and potential employers, ultimately helping women to transform their professional lives.

EKTO VR is a Pittsburgh-based developer of wearable locomotion technology for virtual reality, including a motorized device called Traverse and wearable robotic boots. The devices use rotating plates and wheels to simulate walking in VR, enabling users to move in a defined space while remaining in place, which helps reduce motion sickness. The technology aims to enhance the realism of training simulations and immersive VR experiences for users around the world.

Adrich is a Pittsburgh-based company that develops a consumer insights platform consisting of smart packaging hardware and customized software. The platform autonomously collects and transmits product usage data via product labels, capturing day and time, geolocation, and volumetric usage in real time. This data helps brands and retailers understand trends, behaviors, and usage patterns, supporting post-purchase engagement, retention, and targeted service.

Leaders of Change is a benefit corporation that aims to develop sustainable social and economic business solutions. It makes their services accessible to organizations and businesses that typically do not have the access. The corporation assess wins, provide action steps, and develops a plan to facilitate and provide tangible objectives to get companies moving in the right direction. It was founded in Pittsburgh, Pennsylvania in 2019.

ARIN Technologies designs and delivers high-accuracy indoor positioning systems that enable real-time location tracking within buildings. Based in Pittsburgh and founded around 2015, the company uses ultra-wideband technology to provide precise positioning for indoor work environments, supporting situational awareness around material handling equipment such as forklifts. Its offerings combine hardware and software to improve safety, reduce collisions, and monitor productivity, contributing to safer workflows and efficient operations for industrial customers.

Touchwood Labs, Inc. is an innovative company based in Pittsburgh, Pennsylvania, founded in 2019. The company specializes in developing technology for office and home furniture, focusing on creating interactive and screenless interfaces. Its proprietary invisible displays can be embedded beneath the surface of various materials, such as wood or plastic, allowing them to remain hidden until activated. This technology enables users to interact with multiple IoT-connected devices through seamless visual experiences, enhancing the way individuals engage with their environment. Touchwood Labs aims to revolutionize technology interactions by combining mindful design with advanced hardware, thereby fostering healthier relationships with technology in everyday settings.

Treatspace is a Pittsburgh-based healthcare platform that changes how primary and specialty care and hospital systems collaborate by enabling closed-loop referral management and care coordination. The platform supports patient engagement and clinical collaboration by eliminating paper referrals and securely transferring clinical data, while allowing physicians to post accurate, up-to-date, and verifiable information about their practices. It provides networks that connect patients with physicians and facilitates referral and clinical networking among clinicians, enhancing access to care and educational collaboration across providers. Founded in 2012, Treatspace focuses on improving workflows, enabling efficient referrals, and empowering practices to deliver coordinated care.

Subtl Beauty, Inc. is a cosmetics brand founded in 2018 and based in Pittsburgh, Pennsylvania. The company specializes in the production of stackable makeup products designed for contemporary women seeking convenience and flexibility in their beauty routines. Its unique packaging allows for modular, customizable stacks that can easily fit in a gym bag, purse, or back pocket, making them ideal for on-the-go lifestyles. Subtl Beauty's product offerings are crafted for efficiency, easy application, and long-lasting wear, aligning with the values of conscious consumers by being clean, vegan, cruelty-free, paraben-free, and fragrance-free. The company's online sales platform further enhances accessibility for customers seeking innovative, travel-friendly makeup solutions.

Toaster Party is a developer of an animation studio platform used to create quality and engaging cartoons. Its platform allows users to pick from a variety of accessories and backgrounds to customize a character and environment for stories that enable users to create, experiment, collaborate, and share their creativity. It was founded in 2017 and is headquartered in Pittsburgh, Pennsylvania.

Aurochs Brewing Company, established in 2012 and based in Emsworth, Pennsylvania, specializes in crafting gluten-free beers. Inspired by the legendary Aurochs beast, the company brews its beverages using ancient, untamed grains to achieve complex flavors. All products are naturally gluten-free, made without wheat, barley, or rye, ensuring a safe option for those with gluten intolerance. The company's commitment to quality and unique recipes aim to provide consumers with a wild, untamed beer experience, reflecting the spirit of freedom and independence.

Founded in 2000, MedRespond specializes in online healthcare communication services. It offers interactive video-based programming for various healthcare sectors, including pharmaceuticals, managed care, disease management, education programs, and coaching. The company's clients include pharmaceutical companies, disease organizations, managed care providers, health educators, and professional associations.

Honeycomb Credit operates an online platform facilitating debt crowdfunding between small business owners and their communities or investors. Incorporated in 2017, the company is headquartered in Pittsburgh, Pennsylvania.

Founded in 2013 and headquartered in Pittsburgh, Jetpack Workflow offers a cloud-based software solution designed to streamline workflow management for small to medium-sized accounting firms. Its platform enables CPAs, bookkeepers, and accountants to automate and track recurring client work, enhancing productivity and profitability.

Arieca LLC, founded in 2018 and based in Pittsburgh, Pennsylvania, specializes in the development and distribution of Thubber, a thermally conductive rubber composite. This innovative material merges the compliance and elasticity of soft silicone rubber with the thermal conductivity of metal, making it suitable for various applications such as circuit wiring, sensors, and passive heat exchangers. Arieca's product addresses heat management challenges in the electronics industry, enhancing performance while ensuring safe interactions between devices and users. By providing an alternative to traditional rubber, Arieca aims to improve the efficiency of electronic components across multiple sectors.

Ariel Precision Medicine, Inc. is an integrated genomics and digital health company focused on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases and disorders. Founded in 2015 and headquartered in Pittsburgh, Pennsylvania, the company develops innovative clinical decision support tools aimed at simplifying personalized treatment in both emergency departments and clinical settings. One of its key offerings is ArielDx, a cloud-based tool designed to enhance the diagnosis and treatment of pancreatic disease, thereby improving patient outcomes through tailored healthcare solutions.

Nivo1, LLC is a technology company based in Pittsburgh, Pennsylvania, specializing in automated invoice processing software for accounts payable. Founded in 2016, Nivo1 initially emerged as a consulting firm with extensive expertise in ERP systems and AP automation. The company recognized a significant need for an integrated solution that could streamline accounts payable processes, responding to client demands for a feature-rich yet affordable software. Nivo1's automated invoice processing system is designed to be robust, scalable, and workflow-driven, seamlessly integrating with existing ERP applications. This software aims to minimize data-entry errors and enhance business operations, allowing companies to connect with suppliers efficiently and access low-cost working capital, all while ensuring secure cloud and mobile functionality.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Wise Telemetry, LLC is a provider of gas sensor systems designed for gas distributors to monitor real-time supply and usage data at customer sites. Founded in 2014 and headquartered in Pittsburgh, Pennsylvania, the company offers a solution that automatically determines and communicates a gas cylinder's size, fill level, and usage rate without requiring user input or special programming. This capability enhances delivery route planning, usage tracking, and future demand predictions, allowing clients to optimize their operations and achieve cost savings. Wise Telemetry's technology is applicable across various sectors, including medical, manufacturing, energy, and construction. Originally known as BreatheWise, LLC, the company rebranded in May 2017 to reflect its focus on telemetry solutions.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Meter Feeder, Inc. is a technology company based in Braddock, Pennsylvania, founded in 2014. It specializes in providing affordable payment and enforcement solutions for small to mid-sized governments. The company has developed a mobile application that allows users to locate and pay for parking conveniently through their devices. In addition to the app, Meter Feeder offers a parking enforcement tool known as Meter Reader, which includes an Android tablet and a Bluetooth printer, enabling enforcement officers to verify payments and issue citations efficiently. Meter Feeder's solutions integrate seamlessly with existing parking infrastructure, eliminating the need for municipalities to invest in new meters or kiosks, and promoting the adoption of electronic payment methods among users.

Carmell was founded in 2007 to commercialize technology developed jointly at Carnegie Mellon University and Allegheny General Hospital. The proprietary technology enables the manufacture of biologically-active plastics from blood plasma for treating injuries to bone and connective tissue. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell's plastics can be simply viewed as plastic forms of ultra-concentrated blood clots; they therefore represent the ideal biomaterials, using the body's own growth and regenerative factors to naturally promote tissue healing. The Company is focused on the sports medicine market, with products designed to accelerate healing and produce better clinical outcomes in treating injuries to connective tissue (e.g., tendons, ligaments and cartilage).

Ahemet Antidotes is a biotechnology company based in Pittsburgh, Pennsylvania, founded in 2020. The company focuses on developing organic biologic treatments for livestock, aimed at reducing antibiotic resistance. Its innovative solutions are designed to prevent and treat diseases such as mastitis and pink-eye, addressing critical health issues in animals while promoting sustainable practices in agriculture. By replacing synthetic antibiotics with organic alternatives, Ahemet Antidotes seeks to enhance animal welfare and contribute to the overall health of livestock.

Flexable, LLC is a childcare platform based in Pittsburgh, Pennsylvania, that connects parents with vetted caregivers. Founded in 2016, the platform allows parents to invite trusted caregivers and check their availability for various childcare needs, including part-time, full-time, or occasional care for events. Flexable also facilitates the search for new caregivers in local areas, promoting convenience and accessibility in the childcare market. By offering on-site childcare solutions for professional and personal events, Flexable aims to support working parents and enhance attendance at conferences and gatherings. The company has experienced significant growth since its inception, positioning itself as a trusted resource for families seeking reliable childcare options.

Carnegie Mellon University is a renowned private research university, offering undergraduate and graduate programs across diverse fields, with a strong focus on technology and arts. It is particularly distinguished for its School of Computer Science, recognized globally for its research and education, and the Heinz College of Information Systems and Public Policy, which uniquely combines management and policy expertise. The university serves various sectors, including education, technology, and the arts, contributing significantly to these fields through its academic programs and research.

CapSen Robotics develops advanced computer vision systems that enable machines to comprehend and navigate cluttered environments. Their core technology, derived from MIT research on 3D object detection, empowers robots and automation systems in various industries such as manufacturing, logistics, and retail inventory management.

Rhabit Analytics is a Pittsburgh-based software company that develops an online talent management platform and continuous employee feedback system. The solution supports performance management, employee engagement, development, and succession planning, delivering quantitative data to help human resources, employees, and executives make better workforce decisions. It emphasizes lightweight, easy-to-use feedback, capturing 30-plus data points per employee each week to fuel people analytics that span the entire employee experience. In addition to software, the company offers consulting services to help translate data into actionable leadership insights and guide investments in development. Founded in 2017, Rhabit Analytics helps organizations identify top performers, boost engagement, and optimize development programs.

Creegh Pharmaceuticals specializes in the pharmaceutical preparation industry. It was founded in 2018 and headquartered in Pittsburgh, Pennsylvania.

Cassian Solutions, Inc. is a company based in Phoenixville, Pennsylvania, that specializes in developing innovative medication management solutions. Founded in 2018, it designs and manufactures a unique phone case medication dispenser alongside a comprehensive application that enhances patient adherence to prescribed treatments. The app features tools for outcome collection, biometric verification, medication reminders, adherence verification, environmental sensing, treatment analysis, real-time communication, and medication distribution. Cassian Solutions serves a diverse clientele, including pharmacies, clinical trial companies, drug manufacturers, and insurers. By addressing critical gaps in patient monitoring and data reporting, the company aims to improve health outcomes and streamline the pharmaceutical value chain, ultimately enhancing the medication experience for patients and healthcare providers alike.

Symmetric Health Solutions LLC is a Pittsburgh-based company that specializes in developing software and analytics platforms for the healthcare medical supplies industry. Founded in 2018, the company provides a comprehensive suite of supply chain data solutions that include management of medical devices and pharmaceuticals, price benchmarking, product standardization, and expense tracking. Its platform enables healthcare providers to access vital data and intelligence, identify savings opportunities, and assess supply chain risks. Additionally, Symmetric Health Solutions offers professional support services to enhance the efficiency and effectiveness of supply chain operations within the healthcare sector. The company also maintains offices in New York and Washington, D.C.

Retirement Atlas, LLC is a Pittsburgh-based company established in 2019 that operates a platform designed to connect individuals with suitable senior living options. The platform provides comprehensive information about various types of senior living communities, including continuing care communities, personal care homes, assisted living facilities, and skilled nursing homes. By leveraging extensive datasets from Medicare regarding quality of care, as well as data from health departments and insurance agencies concerning inspections, licenses, and financial stability, Retirement Atlas aims to facilitate informed decision-making for families and individuals seeking senior living solutions. Additionally, the company conducts thorough research to gather cost and amenity details from nearly all senior living communities in Pennsylvania.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Rapid TPC, LLC is a manufacturer based in Pittsburgh, Pennsylvania, that specializes in the development of an automated platform technology for producing thermoplastic composite parts. Founded in 2013, the company focuses on creating lightweight, high-strength components using advanced materials such as carbon fiber, fiberglass, and aramid fibers. Rapid TPC employs automation in its production processes to efficiently manufacture composite parts reinforced with various polymers and organic fibers. This innovative approach enables clients to overcome production bottlenecks, scale their sales volumes, and meet increasing demand without the constraints typically associated with manufacturing limitations. Through its expertise in forming and prototyping, Rapid TPC supports a range of industries seeking durable and lightweight solutions.

UpContent develops a SaaS platform that discovers brand mentions and curates digital content from various sources like news articles, blogs, and social media. Its tool automates the content discovery process, allowing users to engage audiences effectively. Founded in 2015, UpContent is headquartered in Pittsburgh, Pennsylvania.

nanoGriptech, Inc. is a Pittsburgh-based company founded in 2012 that specializes in the manufacture of micro-fibrillar polymer-based dry adhesives and surfaces. Its key product offerings include Setex Gecko Tape, a reusable, residue-free tape, and the Setex Ultra-Thin Fastener, designed for seamless integration with smooth surfaces. The company draws inspiration from nature, mimicking the adhesion mechanism of gecko feet to create durable, versatile adhesives suitable for a wide range of applications. These include wearables, sports equipment, semiconductors, robotics, medical devices, automotive, and packaging. With a focus on innovation, nanoGriptech has established partnerships with several multinational corporations and has recently initiated its first sales in the high-friction clothing material market.

Gridwise develops a mobile application for gig economy drivers, empowering them with real-time insights to maximize earnings. Its platform offers demand alerts, passenger data tracking, mileage logging, tax deduction calculation, and performance reporting.

Founded in 1994, PittMoss manufactures peat-free potting mixtures using recycled paper fibers. Its primary products are PittMoss and PittMoss Prime, serving commercial greenhouse growers, nurseries, and home gardeners in the United States.