Leap enables brands to deploy modern, immersive retail stores that drive growth and acquire customers. By leveraging millions of data points and a platform strategy, Leap makes physical retail more productive and less risky for brands. Its platform also follows a technology-enabled approach and includes all aspects of store development and operations, including physical space, staffing, and managing all technology infrastructure that helps consumer brands to grow and deepen their customer brand experience. The company was founded in 2018 and is headquartered in Chicago, Illinois.
Metagenomi uses metagenomics and machine learning to discover novel genome editing systems for therapeutics development. The company's metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. Metagenomi forges these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific, and have a decreased risk of the immune response. Metagenomi's goal is to revolutionize gene editing for the benefit of patients around the world. The company was founded in 2018 and is headquartered in Emeryville, California.
Checkr is a startup that provides either online access or an API that returns automatically generated background checks. Checkr uses the same data sources as traditional background check companies, but can usually turn it around a lot more quickly than traditional providers. Through Checkr’s advanced background check technology, companies can better understand the dynamics of the changing workforce, bring transparency and fairness to their hiring, and ultimately build a better future for workers. Checkr was founded on 2014 and is headquartered in San Francisco, California and Denver, Colorado.
Arctic Wolf helps companies end cyber risk by providing cloud-native security operations technology. It provides solutions that include Managed Detection and Response, Managed Risk, and Managed Cloud Monitoring, each delivered through the industry’s original concierge security team. Its concierge security engineers act as an extension of a company's internal team, providing tailored threat detection and response, as well as ongoing risk management to keep valuable business data safe.
DNA Script is a disruptive DNA synthesis company engineering biology to accelerate breakthroughs in life science and human health. Their revolutionary enzymatic technology powers the world's first benchtop DNA printer, SYNTAX, enabling labs to print their own synthetic oligos for greater workflow control and faster access to results.
Bombas is an apparel brand that offers and manufactures athletic socks for men, women, teens, and girls through its online platform. The company was founded in 2013 in New York, USA.
Shoreline Biosciences is a biomedical company intended to establish immunotherapies for seriously ill patients. Its proprietary cell therapy technology platform is based on deep expertise in iPSC differentiation methods and genetic programming of the IL-15/CISH pathway for enhanced metabolic fitness and persistence of the engineered NK Cells to improve anti-cancer activity. The company was founded in 2020 and is headquartered in La Jolla, CA, USA.
InterVenn is a life science company unlocking the value of glycoproteomics—glycosylated proteins which are responsible for driving protein function—for the development of transformational healthcare solutions. The glycoproteome is a source of life-critical information about human biology that has the potential to improve patient outcomes significantly. Still, it has remained inaccessible due to its vast complexity. InterVenn has pioneered a first-of-its-kind AI-powered platform to decode this layer of biology at a clinically meaningful scale for the first time in history. The company’s platform can produce a robust pipeline of powerful clinical applications, ranging from early disease screening to diagnostics and, potentially, therapeutics. Its proprietary technology platform is accessible to pharma partners seeking rich biology insights to propel their research and development efforts. Founded by Nobel Laureate Dr. Carolyn Bertozzi, world-class scientist and distinguished professor Dr. Carlito Lebrilla and leading AI/ML expert & serial entrepreneur Aldo Carrascoso, InterVenn will contribute to making the new era of personalized, predictive, and preventative care a reality. For more information about InterVenn, visit www.intervenn.com.
Genomatica develops biobased process technologies that enable a better way to produce widely-used chemicals, from alternative feedstocks, with better economics, sustainability, and performance. Genomatica has earned widespread acclaim for its technology; has commercialized processes for the chemical butanediol (for biodegradable plastics and apparel) and for butylene glycol (cosmetics and personal care), and is working on bio-nylon. Awards include the Kirkpatrick Award, for “the most noteworthy chemical engineering technology commercialized in the world” and the ICIS Innovation Award for its Brontide(TM) butylene glycol.
Cybereason Inc. develops a comprehensive cybersecurity platform focused on endpoint protection, including endpoint detection and response, anti-ransomware, anti-malware, and antivirus solutions. Founded in 2012 by a team of elite intelligence professionals, the company offers a suite of products designed to detect, analyze, and respond to cyber threats. Key offerings include Deep Detect & Respond, which analyzes behavioral data to identify suspicious activities; Deep Prevent, aimed at blocking advanced attacks; Deep Investigate, which collects enterprise data for threat analysis; and Deep Respond, a threat detection and response interface. Additionally, Cybereason provides RansomFree, an anti-ransomware solution, alongside various services such as monitoring, investigation, and training. The company is headquartered in Boston and maintains offices in London, Tel Aviv, and Tokyo, leveraging a custom-built in-memory graph to enhance its threat detection capabilities.
Biotheryx is a clinical stage biopharmaceutical company discovering and developing a portfolio of innovative small molecule targeted protein degraders (TPDs) for the treatment of a wide range of diseases with an initial focus on cancer. Members of our founding and scientific teams previously developed the first FDA approved modulators of Cereblon, the most widely validated E3 ligase involved in protein degradation, and have applied their expertise in Cereblon binding to build our proprietary PRODEGY platform. Our platform leverages an extensive patent protected and rationally designed library of Cereblon binders that we believe provides us with a differentiated starting point for drug design of molecular glues, bifunctional degraders and hybrid degraders.
LUMICKS delivers state-of-the-art technologies for the study of biology and cancer at the single-molecule and single-cell levels. It aims to build the unfinished bridge between structure and function at the molecular and cellular levels. Using its product C-Trap Optical Tweezers, Fluorescence Microscopy, scientists are able to analyze complex biological processes in real-time. Similarly, the z-Movi Cell Avidity Analyzer enables the measurement and selection of immune cells based on their real-time interactions with target cells.
Crossover Health designs and delivers a unique and comprehensive employee care experience for companies that understand the financial and cultural return of a healthy, motivated workforce. The company is a primary care medical group that combines advanced health management services and exceptional member experiences within their employee health offering. Crossover Health was founded in 2010 by Scott Shreeve and is based in San Clemente, California.
AbSci, LLC is a biotechnology company based in Portland, Oregon, specializing in protein production technologies for the biopharmaceutical industry. Founded in 2011, AbSci has developed SoluPro, an innovative expression system utilizing genetically engineered E. coli to facilitate the scalable and cost-effective production of antibodies, antibody fragments, and other soluble recombinant proteins. This technology significantly lowers production costs for both novel and existing biologics, enhancing the efficiency of drug discovery and manufacturing processes. AbSci's therapeutic proteins and antibodies play vital roles in treatments for cancer, hormone-related conditions, autoimmune diseases, and blood disorders. The company's approach integrates biologic drug discovery with cell line development, positioning it as a leader in the advancement of next-generation therapeutics.
EGenesis is a biotechnology company developing solid organ and therapeutic cell transplantation to treat diseases. It offers gene editing and genome engineering platform to develop human-compatible organs, tissues, and cells, aiming to provide an alternative solution to the global organ shortage.
Model Medicines uses human expertise and AI to accelerate the development of life-changing drugs at scale. Model Medicines harnesses AI and ML with its ActivPred AI Drug Discovery Platform to discover drugs that may be repositioned to serve as therapeutics to treat patients suffering from humankind’s toughest diseases. The drugs that Model Medicines discovers can enter clinical trials in as little as several months.
NexImmune is an early stage biopharmaceutical company developing novel immuno-therapeutics based on the proprietary Artificial IMmune (AIMTM) technology. The AIM technology provides an important advance in the development of immunotherapies for a variety of cancers and other diseases. The AIM technology has been designed to orchestrate specific immune system responses in a highly controllable and reproducible way independent of the healthiness or abundance of the patient’s natural antigen presenting cell (APC) population. Natural APCs are major players in the body’s immune system as they direct the immune system cells in attacks on specifically targeted antigens and cells. However, under certain disease conditions, natural APCs can be damaged, absent or inactive.
Imago BioSciences is a clinical development company dedicated to translating state-of-the art science into novel medicines for treating diseases that currently pose great challenges to patients, their families and their physicians. The company leverages the skills and extensive experience of its team and the financial commitment of its investors to focus on a small family of orphan diseases. Imago BioSciences translates unique insights into high impact transformative therapies that alter the natural history of disease allowing patients to live longer, disease-free lives. Imago BioSciences was founded in 2012 and is based in Redwood City, California.
Private Equity Round in 2020
Prometheus Biosciences, formerly known as Prometheus Laboratories, is a biotechnology company focused on developing and commercializing innovative pharmaceutical and diagnostic products, primarily for gastrointestinal diseases such as inflammatory bowel disease (IBD). Based in San Diego, California, the company offers a range of diagnostic tests, including Anser IFX, Anser ADA, and IBD sgi Diagnostic, which enable healthcare providers to monitor treatment and optimize patient care. Prometheus also markets therapeutic agents, such as Entocort EC and Imuran, for managing conditions like Crohn's disease and rheumatoid arthritis. Additionally, it provides genetic and serologic testing for celiac disease and lactose intolerance, among other disorders. With a commitment to precision medicine, Prometheus aims to enhance individualized patient care through its advanced diagnostic capabilities and therapeutic solutions. The company was founded in 1995 and operates as a subsidiary of Precision IBD, Inc.
Nuvation Bio is a global biopharmaceutical company focusing on unmet needs in oncology. It engages in treating patients with the most difficult-to-treat cancers for which conventional therapies have failed.
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders (CNS) characterized by neuronal imbalance. Praxis is applying insights from genetic epilepsies to broader neurological and psychiatric disorders, using our understanding of shared biological targets and circuits in the brain.
Goldfinch is a clinical-stage biotech company focused on discovering and developing precision therapies for patients with kidney disease. It is integrating breakthroughs in kidney genetics and biology to identify new therapeutic targets and advance first-in-class drug candidates to treat patients with kidney disease. Its Product Engine will industrialize the integration of genetics and kidney biology and confer a differentiated ability to identify, validate, and pursue novel therapeutic targets to treat progressive kidney disease. The company was founded in 2016 and is based in Cambridge, Massachusetts.
Rubrik offers live data access for recovery and application development by fusing enterprise data management with web-scale IT and eliminating backup software. This marks the end of a decade-long innovation drought in backup and recovery, the backbone of IT. Within minutes, businesses can manage the explosion of data across private and public clouds.
FAASOS, operated by Rebel Foods Services, is an on-demand food delivery platform that primarily functions through a mobile app. It is transforming the way customers order and receive food, serving approximately 10,000 customers daily, with a rapidly increasing user base. The service is currently available in ten cities, focusing exclusively on app-based orders to enhance customer convenience and streamline the delivery process. As a pioneer in the food tech space, FAASOS continues to expand its reach and improve its offerings to meet the growing demand for quick and accessible food delivery solutions.
thredUP is transforming resale with the mission to inspire a new generation of consumers to think secondhand first. By making it easy to buy and sell secondhand, thredUP has become one of the world's largest resale platforms for women's and kids' apparel, shoes and accessories. thredUP is extending the life cycle of clothing, changing the way consumers shop and ushering in a more sustainable future for the fashion industry.
ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s lead product candidate, ORIC-101, is a potent and selective small molecule antagonist of the glucocorticoid receptor, which has been linked to resistance to multiple classes of cancer therapeutics across a variety of solid tumors. ORIC’s second product candidate, ORIC-533, is an orally bioavailable small molecule inhibitor of CD73, a key node in the adenosine pathway believed to play a central role in resistance to chemotherapy- and immunotherapy-based treatment regimens. Beyond these two product candidates, ORIC is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC’s scientific founders, Charles Sawyers, MD, and Scott Lowe, Ph.D., have long records of discovering novel targets in cancer that have led to innovative treatments.
FAASOS, operated by Rebel Foods Services, is an on-demand food delivery platform that primarily functions through a mobile app. It is transforming the way customers order and receive food, serving approximately 10,000 customers daily, with a rapidly increasing user base. The service is currently available in ten cities, focusing exclusively on app-based orders to enhance customer convenience and streamline the delivery process. As a pioneer in the food tech space, FAASOS continues to expand its reach and improve its offerings to meet the growing demand for quick and accessible food delivery solutions.
Foghorn Therapeutics is developing therapies based on a system that directs which genes our cells express, and when, where, and in what order.By manipulating this system with our unique Gene Traffic ControlTM platform, Foghorn will change how genes turn “on” and “off.” Unlike approaches that edit genes, this novel way of thinking will alter what our DNA has in store for us—and rewrite destiny for millions of people living with disease.With Gene Traffic ControlTM Foghorn is pioneering a new, major class of drug targets to develop unprecedented therapies for cancer and other serious diseases. We have already validated multiple targets, are in the process of developing drug candidates in multiple types of cancer and are beginning to explore other diseases.
Pearl is an AI-driven company that enhances patient care in dentistry with FDA-cleared AI capable of identifying diseases in dental X-rays. It also recognizes dozens of dental pathologies and natural anatomy, allowing practitioners, and existing restorations to assess robust data across their practice, spend more time with patients, and prescribe better treatment options. The company also built a suite of solutions to automate tasks in dental laboratories.
PAX Labs is a leader in the design and development of premium, app-controlled vaporization technologies and devices. Headquartered in San Francisco, PAX has become an industry leader through innovation and product design. PAX is committed to taking the guesswork out of cannabis with products that offer quality, transparency, and predictability. The company was founded in 2007 and based in San Francisco, California.
At Dixie, it is our mission to be the trusted source for innovative, safe, effective, and delicious cannabis products — leading the industry through research, education, and advocacy. They handcraft delicious, refreshing, feel-good treats, and indulgences made with pure, premium cannabis. Their products are innovative, safe, effective, and made with a process and care they are proud of. Each item is infused with CO2 extracted THC that is triple lab tested. Established in 2010 as allowed by Colorado House Bill 1284, Dixie Elixirs and Edibles manufactures seven premium THC-infused product lines: Dixie Elixirs Sparkling Beverages, Dixie Edibles, Dixie Dew Drops (sublingual tinctures), Dixie Scrips, Dixie Prime Connoisseur Concentrates, Dixie Topicals, and Dixie Synergy 1:1 CBD and THC formulated Dew Drops and Scrips. As the leader in medical marijuana-infused products, Dixie is proud to receive the first Infused Products Retail Marijuana License.
GOAT is a global marketplace specializing in authentic sneakers, apparel, and accessories from contemporary luxury brands. Founded in 2015 by Daishin Sugano and Eddy Lu in Culver City, California, the platform provides users with access to exclusive drops, the ability to make offers on desired items, and a selection that spans from iconic styles of the past to future classics. GOAT operates both online and through thirteen physical locations across the United States, Asia, and Europe, including distribution and authentication centers that serve 170 international markets. The platform features over 350 brands and has built a community of over 20 million members across 164 countries. By leveraging innovative technology, GOAT has transformed sneaker commerce, ensuring the authenticity of products while bridging the gap between primary and resale markets. Strategic backing from investors such as Foot Locker and prominent venture capital firms underscores its significant presence in the fashion and sneaker industries.
Rumble offers boxing-inspired fitness classes for a full-body strength and conditioning workouts crafted around specially designed water-filled, teardrop-style boxing bags. Rumble incorporates the best principles of the sweet science of boxing and strength training, all to help you develop that lean, strong, and confident fighter's physique. Rumble is HIIT (High-Intensity Interval Training), strength training, metabolic conditioning (METCON), and uppercut throwing cardio in one clean class.
Anaplan is driving a new age of connected planning. Large and fast-growing organizations use Anaplan’s cloud platform in every business function to make better-informed plans and decisions and drive faster, more effective planning processes. Anaplan also provides support, training, and planning transformation advisory services. Anaplan is a privately held company based in San Francisco with 16 offices and over 150 expert partners worldwide.
Bombas is an apparel brand that offers and manufactures athletic socks for men, women, teens, and girls through its online platform. The company was founded in 2013 in New York, USA.
GOAT is a global marketplace specializing in authentic sneakers, apparel, and accessories from contemporary luxury brands. Founded in 2015 by Daishin Sugano and Eddy Lu in Culver City, California, the platform provides users with access to exclusive drops, the ability to make offers on desired items, and a selection that spans from iconic styles of the past to future classics. GOAT operates both online and through thirteen physical locations across the United States, Asia, and Europe, including distribution and authentication centers that serve 170 international markets. The platform features over 350 brands and has built a community of over 20 million members across 164 countries. By leveraging innovative technology, GOAT has transformed sneaker commerce, ensuring the authenticity of products while bridging the gap between primary and resale markets. Strategic backing from investors such as Foot Locker and prominent venture capital firms underscores its significant presence in the fashion and sneaker industries.
Instacart is a grocery delivery startup that delivers in as short as an hour. It focuses on delivering groceries and home essentials, Instacart already has over 500,000 items from local stores in its catalogue. Customers can choose from a variety of local stores including Safeway, Whole Foods, Super Fresh, Harris Teeter, Shaw's, Mariano's, Jewel-Osco, Stanley's, and Costco. Customers can mix items from multiple stores into one order. Instacart has raised funding from Kleiner Perkins Caufield & Byers, Andreessen Horowitz, Sequoia Capital, Y Combinator, Khosla Ventures, and Canaan Partners among other participants.
Lyft is a transportation company that designs, markets, and operates a mobile application connecting drivers with passengers who request rides. The app also facilitates payment. Additionally, it allows riders to schedule rides up to seven days in advance. Lyft primarily focuses its services on college, university, and corporate communities.