IU Ventures

Amplified Sciences LLC is a molecular diagnostics company focused on the early detection of debilitating diseases, particularly pancreatic cancer and kidney disease. Utilizing an ultra-sensitive molecular sensing technology licensed from Purdue University, the company’s platform can detect disease markers at the single molecule level, enabling accurate diagnosis from bodily fluids such as urine and saliva. This versatile technology is designed for scalability to point-of-care applications, allowing for effective disease screening with a favorable cost structure. Amplified Sciences has developed a working prototype and has published proof of concept data, positioning itself to meet significant unmet medical needs in diagnostics. Founded in 2016 and based in West Lafayette, Indiana, the company was previously known as Nutrabiotix.

Plan Forward, LLC is an online platform that focuses on providing dental membership solutions for uninsured patients. Established in 2018 and headquartered in Indianapolis, Indiana, the company partners with dentists and dental practices to create customized in-office membership plans. This platform enables dental providers to offer their services without the complexities of traditional insurance, thereby improving patient access to quality care. Plan Forward's software facilitates the management of membership plans, enhances treatment acceptance, and fosters patient loyalty. It includes features such as pre-built dashboards and compliant membership agreements, making it easier for dental professionals to market their plans and grow their revenue.

Boardable is a software company that specializes in providing a cloud-based platform for nonprofits to enhance board member engagement and facilitate remote collaboration. The platform consolidates essential functions such as meetings, voting, discussions, and document management into a single interface, thereby reducing the complexity associated with traditional board management practices. By centralizing communication and resources, Boardable allows organizations to maintain continuity during transitions in board membership. Key features include automated notifications, secure data storage, video conferencing capabilities, and easy access to contact information for board members, all aimed at streamlining the governance process for nonprofits.

Confluence Pharmaceuticals LLC, founded in 2010 and headquartered in Indianapolis, Indiana, specializes in developing therapeutic medications aimed at addressing social and communication impairments associated with fragile X syndrome and autism spectrum disorders. The company is focused on advancing innovative drug discovery to provide clinically effective treatments for these rare neurological disorders. In addition to its primary focus, Confluence Pharmaceuticals also aims to benefit patients with related conditions such as Rett Syndrome and treatment-resistant anxiety, thereby enhancing the overall quality of life for individuals affected by these disorders.

Folia is a company that specializes in developing productivity applications focused on digital document management. Its key offerings include iAnnotate, a tool designed for reading and annotating documents, and the Folia platform, which facilitates research and analysis. With iAnnotate, users can easily highlight, draw, stamp, and underline documents using touch gestures. The Folia platform allows users to organize, access, annotate, search, and share various types of documents, fostering enhanced productivity and collaboration. Both products enable secure document sharing and real-time collaboration, allowing users to present their ideas effectively. Folia's solutions cater to researchers, professionals, and students, aiming to improve information management and streamline workflows.

iink Payments is a fintech company specializing in financial services for restoration professionals in the wake of insured property losses. The company offers a digital payments network that streamlines the process of verifying and disbursing insurance proceeds, allowing contractors to receive payments more efficiently. With its technology, iink Payments enables restoration professionals to endorse and access property insurance payments electronically, significantly reducing the payment time. Reports indicate that the platform can facilitate payments up to 60 times faster than traditional methods, helping both property owners and contractors return to normalcy more swiftly after a property disaster.

The Bee Corp specializes in developing infrared image analysis software aimed at enhancing the effectiveness of bee pollination. Its primary product, Verifli, utilizes data analytics and infrared inspection technology to monitor the number, health, and distribution of pollinating bees within beehives. This innovative approach assists farmers and beekeepers in measuring the pollination value, determining pricing, and ultimately maximizing crop yields. By providing essential insights into bee populations and their health, The Bee Corp plays a critical role in supporting agricultural productivity and sustainability.

HotDrop is a music discovery platform that connects undiscovered artists with passionate fans. Founded by a team of young music enthusiasts, the platform caters to the evolving landscape of music consumption and discovery. It allows users to quickly discover new music through 30-second snippets, which can be easily shared among friends, enhancing the virality of emerging artists. The app gained significant traction shortly after its launch, achieving over 25,000 downloads within two days and ranking highly on the App Store. By enabling fans to swipe to like, save, and share music, HotDrop creates opportunities for artists to gain exposure and build a following.

Kovina Therapeutics is a pre-clinical biotechnology company focused on developing non-surgical medical treatments for Human Papillomavirus (HPV) infections and related cancers. The company is dedicated to discovering antiviral therapeutics that utilize drug-like compounds to target and inactivate a crucial HPV protein commonly expressed in early, pre-malignant, and cancerous conditions. By doing so, Kovina Therapeutics aims to provide effective treatment options for medical practitioners to address HPV-related health issues, ultimately improving patient outcomes in the fight against these infections and malignancies.

NuCurrent, Inc. is a developer based in Chicago, Illinois, specializing in high-efficiency antennas and inductive components for wireless power applications. Founded in 2009, the company designs, fabricates, and integrates wireless power antennas and surface-mount inductors for various applications, including power electronics, RF devices, and frequency synthesizers. NuCurrent's products comply with industry standards such as the Alliance for Wireless Power and the Wireless Power Consortium, ensuring broad compatibility. The company collaborates closely with original equipment manufacturers (OEMs) and integrators to provide custom-designed, rapid-prototype solutions that enhance efficiency, reduce size, and lower costs. By employing patented designs and advanced manufacturing techniques, NuCurrent aims to improve the durability and performance of wireless power systems, facilitating the evolution of electronic devices.

Apexian Pharmaceuticals, Inc. is a clinical-stage biotechnology company based in Indianapolis, Indiana, focused on developing innovative compounds for cancer treatment. The company's lead product, APX3330, is an oral anticancer agent that targets the APE1/Ref-1 redox protein, a molecule implicated in various cancers, including those affecting the colon, lung, breast, and pancreas. Founded in 2007, Apexian Pharmaceuticals emerged from research conducted by Dr. Mark R. Kelley, which provided insights into the biological mechanisms associated with APE1/Ref-1. In addition to its work in oncology, the company is also exploring treatments for other conditions, such as bladder cancer, sarcomas, age-related macular degeneration, and inflammatory bowel disease. By focusing on the discovery and development of novel pharmaceuticals, Apexian aims to improve patient outcomes through targeted therapies.

Amplified Sciences LLC is a molecular diagnostics company focused on the early detection of debilitating diseases, particularly pancreatic cancer and kidney disease. Utilizing an ultra-sensitive molecular sensing technology licensed from Purdue University, the company’s platform can detect disease markers at the single molecule level, enabling accurate diagnosis from bodily fluids such as urine and saliva. This versatile technology is designed for scalability to point-of-care applications, allowing for effective disease screening with a favorable cost structure. Amplified Sciences has developed a working prototype and has published proof of concept data, positioning itself to meet significant unmet medical needs in diagnostics. Founded in 2016 and based in West Lafayette, Indiana, the company was previously known as Nutrabiotix.

Mentor Collective is a Boston-based company founded in 2013 that specializes in providing platforms for universities to implement and manage mentoring programs. It offers a comprehensive range of services including program design, mentorship operations, a content library, and assessment and analytics to enhance student engagement and success. By connecting students with relevant near-peer mentors, Mentor Collective aims to improve retention rates and overall student experiences. The organization partners with over 120 universities, including notable institutions such as Princeton and UC Davis, to ensure that all students have access to mentorship opportunities. The company has received recognition for its impact in the education sector, including placements in the Inc. 5000 list and accolades from Forbes and BostInno.

iink Payments is a fintech company specializing in financial services for restoration professionals in the wake of insured property losses. The company offers a digital payments network that streamlines the process of verifying and disbursing insurance proceeds, allowing contractors to receive payments more efficiently. With its technology, iink Payments enables restoration professionals to endorse and access property insurance payments electronically, significantly reducing the payment time. Reports indicate that the platform can facilitate payments up to 60 times faster than traditional methods, helping both property owners and contractors return to normalcy more swiftly after a property disaster.

Encamp, Inc. is a software company that focuses on automating environmental compliance and reporting for organizations in the United States. Founded in 2017 and based in Indianapolis, Indiana, Encamp's software solutions help businesses manage their environmental compliance requirements, track hazardous materials, and streamline reporting processes. One of its key offerings, Tier2, allows organizations to fill out and submit annual reports regarding hazardous chemicals, incorporating detailed information beyond the standard Tier 1 report. Additionally, Encamp provides tools for centralized environmental, health, and safety (EHS) information management, including compliance calendars, task reminders, and a comprehensive form library. Through its innovative technology, Encamp aims to assist businesses in effectively aligning their corporate operations with environmental regulations.

Confluence Pharmaceuticals LLC, founded in 2010 and headquartered in Indianapolis, Indiana, specializes in developing therapeutic medications aimed at addressing social and communication impairments associated with fragile X syndrome and autism spectrum disorders. The company is focused on advancing innovative drug discovery to provide clinically effective treatments for these rare neurological disorders. In addition to its primary focus, Confluence Pharmaceuticals also aims to benefit patients with related conditions such as Rett Syndrome and treatment-resistant anxiety, thereby enhancing the overall quality of life for individuals affected by these disorders.

Diagnotes, Inc. is a digital healthcare company based in Indianapolis, Indiana, that specializes in enhancing communication and collaboration within the healthcare industry. Established in 2010, the company offers a clinical communication platform designed to facilitate secure messaging, provider scheduling, patient data management, and documentation of discussions. This platform is tailored to the needs of various stakeholders, including patients, physicians, care teams, hospitals, health systems, and physician practices, enabling them to efficiently manage all patient-related communications. Diagnotes' applications are intuitive and easily adopted, serving a diverse clientele that includes large health systems, community hospitals, long-term care facilities, and behavioral health organizations. The platform supports a range of functionalities, from simple messaging to telehealth consultations, ensuring effective communication among healthcare professionals and their patients on a unified, cloud-based system.

Canopy operates an online platform designed for frontline sales managers, providing tools to enhance sales performance and decision-making. The platform offers real-time data insights that help managers identify wins and losses at the individual seller level, enabling proactive coaching and support for sales representatives. By monitoring pipeline and rep data, Canopy alerts leaders to potential issues before they affect deals, thereby improving forecast accuracy and driving strategic change. The platform also highlights performance trends, allowing managers to track team dynamics and diagnose issues effectively. Originally known as Loupe Software, Inc., Canopy was incorporated in 2019 and is headquartered in Indianapolis, Indiana.

Encamp, Inc. is a software company that focuses on automating environmental compliance and reporting for organizations in the United States. Founded in 2017 and based in Indianapolis, Indiana, Encamp's software solutions help businesses manage their environmental compliance requirements, track hazardous materials, and streamline reporting processes. One of its key offerings, Tier2, allows organizations to fill out and submit annual reports regarding hazardous chemicals, incorporating detailed information beyond the standard Tier 1 report. Additionally, Encamp provides tools for centralized environmental, health, and safety (EHS) information management, including compliance calendars, task reminders, and a comprehensive form library. Through its innovative technology, Encamp aims to assist businesses in effectively aligning their corporate operations with environmental regulations.

Qumulex Inc. is a software development company based in Fishers, Indiana, focused on the physical security industry. Founded in 2018, it specializes in unified video surveillance and access control solutions tailored for security integrators. The company's platform incorporates cloud IoT technology, offering features such as a progressive web application, support for third-party and cloud-to-cloud integrations, and end-to-end encryption. Its design allows for full local functionality even when cloud connectivity is unavailable, enabling customers to manage multiple sites with a single login. Qumulex aims to streamline setup and maintenance processes, providing a mobile-first, cyber-secure service that fosters recurring revenue and enhances customer lifetime value.

NuCurrent, Inc. is a developer based in Chicago, Illinois, specializing in high-efficiency antennas and inductive components for wireless power applications. Founded in 2009, the company designs, fabricates, and integrates wireless power antennas and surface-mount inductors for various applications, including power electronics, RF devices, and frequency synthesizers. NuCurrent's products comply with industry standards such as the Alliance for Wireless Power and the Wireless Power Consortium, ensuring broad compatibility. The company collaborates closely with original equipment manufacturers (OEMs) and integrators to provide custom-designed, rapid-prototype solutions that enhance efficiency, reduce size, and lower costs. By employing patented designs and advanced manufacturing techniques, NuCurrent aims to improve the durability and performance of wireless power systems, facilitating the evolution of electronic devices.

Mentor Collective is a Boston-based company founded in 2013 that specializes in providing platforms for universities to implement and manage mentoring programs. It offers a comprehensive range of services including program design, mentorship operations, a content library, and assessment and analytics to enhance student engagement and success. By connecting students with relevant near-peer mentors, Mentor Collective aims to improve retention rates and overall student experiences. The organization partners with over 120 universities, including notable institutions such as Princeton and UC Davis, to ensure that all students have access to mentorship opportunities. The company has received recognition for its impact in the education sector, including placements in the Inc. 5000 list and accolades from Forbes and BostInno.

NERx BioSciences Inc is focused on discovering and developing targeted therapeutics for cancer, specifically lung and ovarian cancers. Established in 2009 and based in Indianapolis, Indiana, the company specializes in creating novel biopharmaceutical compounds designed to repair the DNA damage response pathway. By developing Ku protein inhibitors, NERx BioSciences aims to target specific cellular processes that allow for the detection and elimination of cancer cells while minimizing effects on healthy cells. This approach enables medical researchers to identify preclinical anti-cancer targets, facilitating faster, safer, and more cost-effective cancer treatment options.

Tend.ly is a care relationship management system designed to enhance engagement between care providers and the families of those they serve, including senior living facilities, adult day services, and early childhood education centers. This user-friendly and secure application enables care providers to send real-time updates, including photos and videos, to families via text and email, fostering meaningful connections and providing peace of mind. By facilitating better communication, Tend.ly allows caregivers to dedicate more time to quality care while also differentiating themselves in a competitive market. The data collected through the platform aids care providers in making informed business decisions, ultimately leading to improved operational efficiency and family engagement.

OpenINSIGHTS is an AI-driven customer analytics platform that provides predictive insights to help organizations generate incremental revenue. The platform integrates into clients' technology clouds, utilizing a cognitive framework to create tailored predictions for every customer across all product lines and stages of their lifecycle. This self-adapting data empowers clients to enhance their sales strategies and optimize margins, facilitating strategic customer growth throughout the organization.

OpenINSIGHTS is an AI-driven customer analytics platform that provides predictive insights to help organizations generate incremental revenue. The platform integrates into clients' technology clouds, utilizing a cognitive framework to create tailored predictions for every customer across all product lines and stages of their lifecycle. This self-adapting data empowers clients to enhance their sales strategies and optimize margins, facilitating strategic customer growth throughout the organization.

Doxly, Inc. is a provider of transaction-management software specifically designed for law firms. Established in 2016 and headquartered in Indianapolis, Indiana, Doxly aims to transform the traditionally cumbersome process of managing legal transactions into a more streamlined and efficient experience. The platform enhances the transaction process by automating workflows, facilitating document-level collaboration, and offering tools for diligence, closing checklists, and transaction analytics. By focusing on the unique needs of legal professionals, Doxly seeks to improve client experiences and strengthen law practices, making it easier for attorneys to manage all aspects of their transaction work. As of August 2019, Doxly operates as a subsidiary of Freedom Solutions Group, LLC.

Allinaire Therapeutics, LLC is a biotechnology company based in Cleveland, Ohio, founded in 2015. The company focuses on developing innovative therapeutics for chronic obstructive pulmonary disease (COPD) and other pulmonary diseases. Its research is grounded in the discovery of a novel therapeutic target identified by its scientific founders, Irina Petrache, MD, and Matthias Clauss, Ph.D. This target is significant in the understanding and treatment of lung diseases, including pulmonary arterial hypertension (PAH). By targeting this mechanism, Allinaire Therapeutics aims to provide new treatment options that could improve clinical outcomes for patients suffering from various cardiopulmonary conditions.

PrecisionHawk Inc. is a technology company that specializes in providing drones, sensors, and software solutions tailored for various industries, including agriculture, construction, energy, insurance, and government. Founded in 2010 and headquartered in Raleigh, North Carolina, the company has established additional locations in Texas, Indiana, Canada, Virginia, and Colorado. PrecisionHawk combines unmanned aerial systems with remote sensing technologies and advanced data analytics to enhance business operations and decision-making processes. Its platform offers an end-to-end solution for aerial data collection, processing, and analysis, delivering actionable insights through its proprietary software tools. The company also owns DataMapper, a software for aerial data management, Terraserver, a satellite imagery provider, and LATAS, a platform focused on low-altitude traffic and airspace safety for drones.

DinnerCall is a mobile app that enables users to search, order, and pickup family-style dinner from grocery stores. It was launched by Gerry Hays, Ashton Chaffee, and Akram Mnif in September 2015 and it operates from San Francisco, California.

MatterFab specializes in 3D metal printing services aimed at overcoming the limitations of traditional industrial fabrication. The company offers a comprehensive production solution that includes advanced printers, material supply, traceable powder cartridges, and various support services such as training, education, maintenance, and application engineering. By providing these resources, MatterFab enables clients to accelerate their adoption of additive manufacturing, thereby reshaping their manufacturing processes and enhancing production capabilities. Through its innovative approach, MatterFab plays a significant role in advancing the integration of 3D printing technology within organizations.

Sharpen Technologies Inc. specializes in developing software and voice solutions that enhance communication between businesses and their customers. The company offers a Communications Platform-as-a-Service that serves as a comprehensive contact center platform, equipping leadership, operations, and IT teams with essential tools and real-time analytics to support frontline customer service agents. Its cloud-native platform, designed without legacy constraints, allows for customization through open REST APIs, enabling clients to tailor solutions to their specific customer service challenges. By addressing the needs of both contact center agents and IT departments, Sharpen aims to improve agent efficiency and job satisfaction, ultimately fostering better customer experiences. Founded in 2011 and based in Indianapolis, Indiana, Sharpen Technologies was previously known as Weeks Communications Inc. before rebranding in August 2016. Its solutions cater to various sectors, including education, marketing, retail, and insurance.

Haven is a company based in Fishers, Indiana, that offers a mobile application and website designed for homeowners. Its platform utilizes predictive technology to help users understand and anticipate their home's maintenance needs. The application sends personalized reminders for updates, tracks preferences, and organizes receipts and records. It caters to both DIY homeowners and those seeking professional assistance by providing a system for scheduling services with licensed and insured service professionals, as well as facilitating payments within the app. This comprehensive approach aims to give homeowners confidence and support in managing their home maintenance responsibilities effectively.

MatterFab specializes in 3D metal printing services aimed at overcoming the limitations of traditional industrial fabrication. The company offers a comprehensive production solution that includes advanced printers, material supply, traceable powder cartridges, and various support services such as training, education, maintenance, and application engineering. By providing these resources, MatterFab enables clients to accelerate their adoption of additive manufacturing, thereby reshaping their manufacturing processes and enhancing production capabilities. Through its innovative approach, MatterFab plays a significant role in advancing the integration of 3D printing technology within organizations.

PrecisionHawk Inc. is a technology company that specializes in providing drones, sensors, and software solutions tailored for various industries, including agriculture, construction, energy, insurance, and government. Founded in 2010 and headquartered in Raleigh, North Carolina, the company has established additional locations in Texas, Indiana, Canada, Virginia, and Colorado. PrecisionHawk combines unmanned aerial systems with remote sensing technologies and advanced data analytics to enhance business operations and decision-making processes. Its platform offers an end-to-end solution for aerial data collection, processing, and analysis, delivering actionable insights through its proprietary software tools. The company also owns DataMapper, a software for aerial data management, Terraserver, a satellite imagery provider, and LATAS, a platform focused on low-altitude traffic and airspace safety for drones.

amSTATZ is a cloud based software for fitness professionals and studios who want to save time, stay organized and grow client relationships. Unlike traditional fitness business software, amSTATZ streamlines your operations, from a simplified booking & payment process to the workout homework you assign to clients between sessions.

PrecisionHawk Inc. is a technology company that specializes in providing drones, sensors, and software solutions tailored for various industries, including agriculture, construction, energy, insurance, and government. Founded in 2010 and headquartered in Raleigh, North Carolina, the company has established additional locations in Texas, Indiana, Canada, Virginia, and Colorado. PrecisionHawk combines unmanned aerial systems with remote sensing technologies and advanced data analytics to enhance business operations and decision-making processes. Its platform offers an end-to-end solution for aerial data collection, processing, and analysis, delivering actionable insights through its proprietary software tools. The company also owns DataMapper, a software for aerial data management, Terraserver, a satellite imagery provider, and LATAS, a platform focused on low-altitude traffic and airspace safety for drones.

Diagnotes, Inc. is a digital healthcare company based in Indianapolis, Indiana, that specializes in enhancing communication and collaboration within the healthcare industry. Established in 2010, the company offers a clinical communication platform designed to facilitate secure messaging, provider scheduling, patient data management, and documentation of discussions. This platform is tailored to the needs of various stakeholders, including patients, physicians, care teams, hospitals, health systems, and physician practices, enabling them to efficiently manage all patient-related communications. Diagnotes' applications are intuitive and easily adopted, serving a diverse clientele that includes large health systems, community hospitals, long-term care facilities, and behavioral health organizations. The platform supports a range of functionalities, from simple messaging to telehealth consultations, ensuring effective communication among healthcare professionals and their patients on a unified, cloud-based system.

Sharpen Technologies Inc. specializes in developing software and voice solutions that enhance communication between businesses and their customers. The company offers a Communications Platform-as-a-Service that serves as a comprehensive contact center platform, equipping leadership, operations, and IT teams with essential tools and real-time analytics to support frontline customer service agents. Its cloud-native platform, designed without legacy constraints, allows for customization through open REST APIs, enabling clients to tailor solutions to their specific customer service challenges. By addressing the needs of both contact center agents and IT departments, Sharpen aims to improve agent efficiency and job satisfaction, ultimately fostering better customer experiences. Founded in 2011 and based in Indianapolis, Indiana, Sharpen Technologies was previously known as Weeks Communications Inc. before rebranding in August 2016. Its solutions cater to various sectors, including education, marketing, retail, and insurance.

DRIFT Eyewear Co. specializes in the design and manufacture of eco-friendly eyeglasses. Founded in 2011 by Chris Manz, the company is headquartered in Chicago, Illinois. DRIFT Eyewear markets its products through various retailers across the United States, Canada, Australia, Costa Rica, Japan, and South Korea, emphasizing sustainability in its offerings. The company's commitment to environmentally conscious practices distinguishes it in the eyewear industry.

Cause.it Inc. is a company based in Indianapolis, Indiana, founded in 2011, that specializes in developing mobile applications aimed at enhancing engagement between higher education institutions and their alumni. The platform allows schools to connect with alumni by enabling them to create personalized affinity profiles based on their interests. This information helps institutions improve their engagement strategies and tailor fundraising campaigns more effectively. Cause.it seeks to modernize the fundraising landscape by moving away from traditional methods such as direct mail and telemarketing, instead focusing on digital solutions that provide a more streamlined and personalized experience for alumni. Additionally, the application offers tools for community volunteers to sign up for nonprofit service events, thus fostering a deeper connection between volunteers and organizations. Overall, Cause.it aims to simplify a fragmented market and enhance the donor experience through innovative digital tools.

Courseload, Inc. is an innovative early stage educational software company. Our SaaS offering reduces the cost of most commercially available textbooks and proprietary content by up to 2/3 and provides electronic access to self-generated, open source and fair use educational materials, saving students thousands of dollars over their four year undergraduate careers, while improving both revenue and margin for textbook publishers. Additionally, the Courseload solution offers collaborative teaching and learning capabilities to students and professors that improve learning outcomes as proven by National Science Foundation-sponsored research at a major university. The Courseload solution strongly resonates with those working to make the total cost of college more affordable while enhancing educational results, yielding millions of dollars in aggregate savings to the students of schools each year. Courseload continues its expansion in the higher education and K12 spaces, working with multiple Big Ten schools, private liberal arts and technology universities, community and technical colleges, and the premier K12 school in the State of Indiana. Expansion to other universities, colleges and schools continues

Aarden Pharmaceuticals is a small molecule drug discovery and development company. The company’s novel technology is a chemistry breakthrough that will enable it to make drugs against a previously un-druggable set of intracellular phosphatase (PTP) disease targets. The technology was developed in the laboratory of Dr. Zhong-Yin Zhang, Robert A. Harris Professor and chairman of biochemistry and molecular biology at the Indiana University School of Medicine. Zhang is an internationally recognized expert in the field of protein tyrosine phosphatases (PTPs). Aarden’s first programs are focused on infectious disease, cancer, and metabolic and autoimmune conditions.

Apexian Pharmaceuticals, Inc. is a clinical-stage biotechnology company based in Indianapolis, Indiana, focused on developing innovative compounds for cancer treatment. The company's lead product, APX3330, is an oral anticancer agent that targets the APE1/Ref-1 redox protein, a molecule implicated in various cancers, including those affecting the colon, lung, breast, and pancreas. Founded in 2007, Apexian Pharmaceuticals emerged from research conducted by Dr. Mark R. Kelley, which provided insights into the biological mechanisms associated with APE1/Ref-1. In addition to its work in oncology, the company is also exploring treatments for other conditions, such as bladder cancer, sarcomas, age-related macular degeneration, and inflammatory bowel disease. By focusing on the discovery and development of novel pharmaceuticals, Apexian aims to improve patient outcomes through targeted therapies.