IU Ventures

Amplified Sciences is a molecular diagnostics company developing a point-of-care platform that enables early detection of debilitating diseases. Its sensor-based and optical reporter systems, combined with machine learning and multi-analyte assays, target cancers and chronic conditions such as pancreatic cancer and kidney disease. The technology supports detection of low-abundance disease markers in urine and saliva, with scalability to cost-effective point-of-care formats. The company leverages ultra-sensitive sensing and composition-of-matter intellectual property licensed from Purdue University to deliver single-molecule level detection. Its portfolio aims to improve patient outcomes by enabling rapid, minimally invasive testing, reducing unnecessary procedures, and expediting diagnosis across oncology and other disease areas. The platform has demonstrated prototype data and is positioned for broad applicability across multiple disease states.

Plan Forward, LLC is a company that specializes in developing an online dental membership platform aimed at providing uninsured patients with access to dental care alternatives. Founded in 2018 and headquartered in Indianapolis, Indiana, Plan Forward collaborates with dentists, group practices, and dental office managers to create and manage in-house membership plans tailored for patients who do not have traditional insurance. The platform is designed to enhance patient loyalty, increase treatment acceptance, and support revenue growth for dental practices. By offering user-friendly software with pre-built dashboards, Plan Forward enables dental professionals to effectively manage membership plans, market their services, and ensure compliance with necessary regulations.

Boardable is a software company that specializes in providing a cloud-based platform designed to enhance board member engagement and facilitate remote collaboration for nonprofits. By consolidating essential functions such as meeting scheduling, voting, discussions, and document storage into a single interface, Boardable alleviates the challenges of traditional board management, which often relies on email and disparate file storage. The platform features automated notifications, secure document handling, and video conferencing capabilities, allowing organizations to efficiently manage meetings and foster communication among board members. This integrated approach ensures continuity in board operations, particularly as members transition in and out of the organization.

Confluence Pharmaceuticals LLC is a biopharmaceutical company based in Indianapolis, Indiana, founded in 2010. The company specializes in developing therapeutic medications aimed at addressing social and communication impairments associated with fragile X syndrome and autism spectrum disorders. Confluence Pharmaceuticals focuses on novel drug discovery, creating treatments for these rare neurological disorders. Its innovative approach not only targets the core symptoms of autism spectrum disorders and fragile X syndrome but also extends to related conditions such as Rett syndrome and treatment-resistant anxiety, ultimately aiming to enhance the quality of life for affected individuals.

Folia develops productivity applications for digital document work. Its key products are iAnnotate for reading and annotating documents, and Folia for streamlined research and analysis. Users can highlight, draw, stamp, underline, collaborate in real-time, securely share documents, and present ideas persuasively using these tools.

iink Payments is a fintech company operating within the financial services sector, focused on enhancing the payment processes for restoration professionals dealing with insured property losses. It offers a digital payments network that facilitates the swift receipt of payments, allowing property owners and contractors to recover more quickly after disasters. The company's platform automates the verification and disbursement of insurance proceeds, enabling contractors to access property insurance payments efficiently. By streamlining property claim processes, iink Payments has been shown to expedite payments to insurance restoration professionals, allowing them to receive funds up to 60 times faster than conventional methods.

The Bee Corp provides an infrared image analysis platform, Verifli, that applies data analytics to beehives to support pollination and crop yield. The platform uses infrared inspection technology to monitor the number, health, and distribution of pollinating bees, enabling growers to optimize pollination, quantify pollination value, and protect yields.

HotDrop is a Techstars- and venture-backed music discovery platform that connects emerging artists with superfans. The platform enables discovery through 30-second clips and a swipe-to-like, save, and share workflow, creating viral exposure for new music as fans spread tracks within their networks. It addresses a shifting landscape in music discovery and consumption by prioritizing rapid discovery and social sharing. In its early launch period, the app demonstrated strong traction, recording more than 25,000 downloads within two days and ranking seventh on the App Store.

Kovina Therapeutics is a preclinical biotechnology company focused on developing non-surgical, medical treatments for Human Papillomavirus (HPV) infections and associated cancers. The company's approach involves creating antiviral therapeutics that target and inactivate a specific HPV protein consistently expressed in early-stage infections and cancers. This targeted strategy aims to enable medical practitioners to treat patients infected with HPV and HPV-related cancers without the need for surgery.

NuCurrent is a Chicago-based developer and manufacturer of wireless power technologies, founded in 2009. It designs, fabricates, and integrates wireless power antennas, surface-mount inductors, and inductive coils for low- and high-frequency systems, and provides custom-designed prototypes. The company offers high-efficiency antennas and components suitable for a range of applications, and supports rapid prototyping and integration for OEMs and system integrators. Its wireless power solutions comply with major standards including A4WP, Qi, and PMA, enabling collaboration with automotive, consumer, industrial, IoT, mobile, and wearable device manufacturers. By focusing on optimized designs and manufacturing techniques, NuCurrent aims to deliver higher efficiency, smaller form factors, greater durability, and lower costs in wireless power deployment.

Apexian Pharmaceuticals is a clinical-stage biotechnology company developing novel compounds to treat cancer. Its lead drug candidate, APX3330, targets the APE1/Ref-1 redox protein found in many cancers. Founded on Dr. Mark R. Kelley's scientific discoveries at Indiana University School of Medicine, the company aims to safely and effectively treat various diseases.

Amplified Sciences is a molecular diagnostics company developing a point-of-care platform that enables early detection of debilitating diseases. Its sensor-based and optical reporter systems, combined with machine learning and multi-analyte assays, target cancers and chronic conditions such as pancreatic cancer and kidney disease. The technology supports detection of low-abundance disease markers in urine and saliva, with scalability to cost-effective point-of-care formats. The company leverages ultra-sensitive sensing and composition-of-matter intellectual property licensed from Purdue University to deliver single-molecule level detection. Its portfolio aims to improve patient outcomes by enabling rapid, minimally invasive testing, reducing unnecessary procedures, and expediting diagnosis across oncology and other disease areas. The platform has demonstrated prototype data and is positioned for broad applicability across multiple disease states.

Mentor Collective offers a platform and services that enable universities to design, run, and evaluate mentoring programs. Its offerings include program design and management, mentorship operations, content libraries, research and analytics, and software to support online orientation, engagement, and progress tracking. The platform provides real-time insights into student needs and actions to improve retention and graduation outcomes, with a network of partner institutions that use near-peer mentoring to broaden access to guidance. The company focuses on scaling mentoring across campuses to help all students connect with relevant mentors and receive timely support throughout their college experience.

iink Payments is a fintech company operating within the financial services sector, focused on enhancing the payment processes for restoration professionals dealing with insured property losses. It offers a digital payments network that facilitates the swift receipt of payments, allowing property owners and contractors to recover more quickly after disasters. The company's platform automates the verification and disbursement of insurance proceeds, enabling contractors to access property insurance payments efficiently. By streamlining property claim processes, iink Payments has been shown to expedite payments to insurance restoration professionals, allowing them to receive funds up to 60 times faster than conventional methods.

Founded in 2017, Encamp specializes in automating environmental compliance tasks. Its software centralizes EHS information, tracks hazardous materials, generates automated reports for regulatory bodies, and manages waste documentation.

Confluence Pharmaceuticals LLC is a biopharmaceutical company based in Indianapolis, Indiana, founded in 2010. The company specializes in developing therapeutic medications aimed at addressing social and communication impairments associated with fragile X syndrome and autism spectrum disorders. Confluence Pharmaceuticals focuses on novel drug discovery, creating treatments for these rare neurological disorders. Its innovative approach not only targets the core symptoms of autism spectrum disorders and fragile X syndrome but also extends to related conditions such as Rett syndrome and treatment-resistant anxiety, ultimately aiming to enhance the quality of life for affected individuals.

Diagnotes, Inc. is a digital healthcare company based in Indianapolis, Indiana, that specializes in enhancing communication and collaboration within the healthcare industry. Founded in 2010, Diagnotes offers a clinical communication platform designed for secure messaging, provider scheduling, patient data management, and documentation of discussions. The platform is tailored to the natural communication habits of healthcare professionals and their patients, facilitating seamless interactions among patients, physicians, care teams, hospitals, and other healthcare entities. Diagnotes serves a diverse clientele, including large health systems, community hospitals, long-term care facilities, and behavioral health organizations. Its applications are versatile, enabling uses from simple secure messaging to telehealth consultations, particularly beneficial for connecting specialists with patients in rural areas through live video. The platform's user-friendly design promotes quick implementation and adoption, making it an integral tool for managing patient-related communications effectively.

Canopy is a technology company that develops and operates an online platform designed for frontline sales managers. The platform provides insights into user data, facilitating a deep understanding of sales performance at the individual seller level. By utilizing data snapshotting, Canopy identifies key opportunities and potential risks, allowing managers to proactively address issues before they affect deals. The platform enhances decision-making, aids in tracking team performance, and supports effective coaching by providing managers with the necessary context to guide their sales representatives. Canopy's innovative approach aims to improve forecast accuracy and drive strategic changes, ultimately enabling clients to achieve consistent success within their sales teams. Founded in 2019 and based in Indianapolis, Indiana, the company was previously known as Loupe Software, Inc.

Founded in 2017, Encamp specializes in automating environmental compliance tasks. Its software centralizes EHS information, tracks hazardous materials, generates automated reports for regulatory bodies, and manages waste documentation.

Founded in 2018, Qumulex develops software for video surveillance and access control, designed specifically for security integrators. Its product offers progressive web applications, third-party integrations, end-to-end encryption, and offline functionality, allowing customers to manage all sites with a single login.

NuCurrent is a Chicago-based developer and manufacturer of wireless power technologies, founded in 2009. It designs, fabricates, and integrates wireless power antennas, surface-mount inductors, and inductive coils for low- and high-frequency systems, and provides custom-designed prototypes. The company offers high-efficiency antennas and components suitable for a range of applications, and supports rapid prototyping and integration for OEMs and system integrators. Its wireless power solutions comply with major standards including A4WP, Qi, and PMA, enabling collaboration with automotive, consumer, industrial, IoT, mobile, and wearable device manufacturers. By focusing on optimized designs and manufacturing techniques, NuCurrent aims to deliver higher efficiency, smaller form factors, greater durability, and lower costs in wireless power deployment.

Mentor Collective offers a platform and services that enable universities to design, run, and evaluate mentoring programs. Its offerings include program design and management, mentorship operations, content libraries, research and analytics, and software to support online orientation, engagement, and progress tracking. The platform provides real-time insights into student needs and actions to improve retention and graduation outcomes, with a network of partner institutions that use near-peer mentoring to broaden access to guidance. The company focuses on scaling mentoring across campuses to help all students connect with relevant mentors and receive timely support throughout their college experience.

NERx BioSciences Inc is focused on discovering and developing targeted therapeutics for cancer, specifically lung and ovarian cancers. Established in 2009 and based in Indianapolis, Indiana, the company specializes in creating novel biopharmaceutical compounds designed to repair the DNA damage response pathway. By developing Ku protein inhibitors, NERx BioSciences aims to target specific cellular processes that allow for the detection and elimination of cancer cells while minimizing effects on healthy cells. This approach enables medical researchers to identify preclinical anti-cancer targets, facilitating faster, safer, and more cost-effective cancer treatment options.

Tend.ly is a care relationship management system designed to enhance engagement between care providers and the families of those they serve, including senior living facilities, adult day services, and early childhood education centers. This user-friendly and secure application enables care providers to send real-time updates, including photos and videos, to families via text and email, fostering meaningful connections and providing peace of mind. By facilitating better communication, Tend.ly allows caregivers to dedicate more time to quality care while also differentiating themselves in a competitive market. The data collected through the platform aids care providers in making informed business decisions, ultimately leading to improved operational efficiency and family engagement.

OpenINSIGHTS is an AI-driven customer analytics and predictive insights platform that focuses on generating replicable incremental revenue for its clients. The company's technology is integrated into the clients' existing cloud infrastructure and employs a cognitive framework to generate predictions for every customer throughout the sales channel, covering all product lines and categories. This capability extends to every stage of the customer lifecycle, allowing organizations to leverage self-adapting data that enhances strategic decision-making. By providing actionable insights, OpenINSIGHTS enables clients to achieve customer growth while optimizing their margins.

OpenINSIGHTS is an AI-driven customer analytics and predictive insights platform that focuses on generating replicable incremental revenue for its clients. The company's technology is integrated into the clients' existing cloud infrastructure and employs a cognitive framework to generate predictions for every customer throughout the sales channel, covering all product lines and categories. This capability extends to every stage of the customer lifecycle, allowing organizations to leverage self-adapting data that enhances strategic decision-making. By providing actionable insights, OpenINSIGHTS enables clients to achieve customer growth while optimizing their margins.

Doxly, Inc. is a technology company based in Indianapolis, Indiana, that specializes in developing transaction-management software specifically designed for law firms. Founded in 2016, Doxly aims to streamline and simplify the complex processes involved in managing legal transactions. The platform enhances efficiency by offering features such as automated workflows, intelligent diligence processes, closing checklists, document-level collaboration, and transaction analytics. By addressing the common frustrations lawyers face during legal transactions, Doxly enables legal professionals to deliver improved client experiences while optimizing their practice management capabilities. In 2019, Doxly became a subsidiary of Freedom Solutions Group, LLC.

Allinaire Therapeutics is a biotechnology company focused on developing novel therapeutics for chronic obstructive pulmonary disease (COPD) and other pulmonary diseases, including cardiopulmonary conditions such as pulmonary arterial hypertension. Incorporated in 2015 and based in Cleveland, Ohio, the company builds on a therapeutic target identified by founders Irina Petrache, MD, and Matthias Clauss, Ph.D., which plays a central role in lung disease development and progression. The goal is to translate this target into treatments that could slow or halt disease progression and improve outcomes for patients with PAH and related conditions.

PrecisionHawk Inc. is a technology company that specializes in providing drones, sensors, and software solutions tailored for various industries, including agriculture, construction, energy, insurance, and government. Founded in 2010 and headquartered in Raleigh, North Carolina, the company has established additional locations in Texas, Indiana, Canada, Virginia, and Colorado. PrecisionHawk combines unmanned aerial systems with remote sensing technologies and advanced data analytics to enhance business operations and decision-making processes. Its platform offers an end-to-end solution for aerial data collection, processing, and analysis, delivering actionable insights through its proprietary software tools. The company also owns DataMapper, a software for aerial data management, Terraserver, a satellite imagery provider, and LATAS, a platform focused on low-altitude traffic and airspace safety for drones.

DinnerCall is a mobile app that enables users to search, order, and pickup family-style dinner from grocery stores. It was launched by Gerry Hays, Ashton Chaffee, and Akram Mnif in September 2015 and it operates from San Francisco, California.

MatterFab is a manufacturing-focused company that provides production-grade 3D metal printing solutions. Based in Bloomington, Indiana, and founded in 2013, MatterFab offers a scalable additive manufacturing platform that combines metal printers, material supply, traceable powder cartridges, and integrated services such as training, maintenance, and application engineering support to accelerate the adoption of additive manufacturing in client organizations. Its offerings enable rapid production of end-use metal parts and help customers deploy additive manufacturing at scale, reshaping industrial fabrication.

Sharpen Technologies, established in 2011 and headquartered in Indianapolis, Indiana, specializes in developing software and voice solutions for businesses to enhance customer communication. Its flagship product, Sharpen, is a Communications Platform-as-a-Service (CPaaS) that equips leadership, operations, and IT teams with tools and data to support frontline customer service teams. The platform offers customizable voice system management, real-time analytics reporting, and omnichannel routing, aiming to improve agent performance and well-being, and ultimately create perfect customer experiences. Serving various sectors such as education, marketing, retail, and insurance, Sharpen caters to agents, supervisors, IT professionals, and executives, addressing decades-old agent issues responsible for poor customer service.

Haven is a technology company based in Fishers, Indiana, that offers a mobile application and website designed to assist homeowners in managing their home maintenance needs. The platform utilizes predictive technology to help users learn about and anticipate necessary updates for their homes. It features a personalized reminder system that tracks preferences, schedules maintenance tasks, and organizes important documents such as receipts and records. Additionally, Haven connects homeowners with licensed, insured, and pre-vetted service professionals, facilitating the scheduling and payment of services directly through the app. By providing these tools, Haven empowers homeowners to take a proactive approach to home maintenance, enhancing their confidence and peace of mind.

MatterFab is a manufacturing-focused company that provides production-grade 3D metal printing solutions. Based in Bloomington, Indiana, and founded in 2013, MatterFab offers a scalable additive manufacturing platform that combines metal printers, material supply, traceable powder cartridges, and integrated services such as training, maintenance, and application engineering support to accelerate the adoption of additive manufacturing in client organizations. Its offerings enable rapid production of end-use metal parts and help customers deploy additive manufacturing at scale, reshaping industrial fabrication.

PrecisionHawk Inc. is a technology company that specializes in providing drones, sensors, and software solutions tailored for various industries, including agriculture, construction, energy, insurance, and government. Founded in 2010 and headquartered in Raleigh, North Carolina, the company has established additional locations in Texas, Indiana, Canada, Virginia, and Colorado. PrecisionHawk combines unmanned aerial systems with remote sensing technologies and advanced data analytics to enhance business operations and decision-making processes. Its platform offers an end-to-end solution for aerial data collection, processing, and analysis, delivering actionable insights through its proprietary software tools. The company also owns DataMapper, a software for aerial data management, Terraserver, a satellite imagery provider, and LATAS, a platform focused on low-altitude traffic and airspace safety for drones.

amSTATZ is a cloud based software for fitness professionals and studios who want to save time, stay organized and grow client relationships. Unlike traditional fitness business software, amSTATZ streamlines your operations, from a simplified booking & payment process to the workout homework you assign to clients between sessions.

PrecisionHawk Inc. is a technology company that specializes in providing drones, sensors, and software solutions tailored for various industries, including agriculture, construction, energy, insurance, and government. Founded in 2010 and headquartered in Raleigh, North Carolina, the company has established additional locations in Texas, Indiana, Canada, Virginia, and Colorado. PrecisionHawk combines unmanned aerial systems with remote sensing technologies and advanced data analytics to enhance business operations and decision-making processes. Its platform offers an end-to-end solution for aerial data collection, processing, and analysis, delivering actionable insights through its proprietary software tools. The company also owns DataMapper, a software for aerial data management, Terraserver, a satellite imagery provider, and LATAS, a platform focused on low-altitude traffic and airspace safety for drones.

Diagnotes, Inc. is a digital healthcare company based in Indianapolis, Indiana, that specializes in enhancing communication and collaboration within the healthcare industry. Founded in 2010, Diagnotes offers a clinical communication platform designed for secure messaging, provider scheduling, patient data management, and documentation of discussions. The platform is tailored to the natural communication habits of healthcare professionals and their patients, facilitating seamless interactions among patients, physicians, care teams, hospitals, and other healthcare entities. Diagnotes serves a diverse clientele, including large health systems, community hospitals, long-term care facilities, and behavioral health organizations. Its applications are versatile, enabling uses from simple secure messaging to telehealth consultations, particularly beneficial for connecting specialists with patients in rural areas through live video. The platform's user-friendly design promotes quick implementation and adoption, making it an integral tool for managing patient-related communications effectively.

Sharpen Technologies, established in 2011 and headquartered in Indianapolis, Indiana, specializes in developing software and voice solutions for businesses to enhance customer communication. Its flagship product, Sharpen, is a Communications Platform-as-a-Service (CPaaS) that equips leadership, operations, and IT teams with tools and data to support frontline customer service teams. The platform offers customizable voice system management, real-time analytics reporting, and omnichannel routing, aiming to improve agent performance and well-being, and ultimately create perfect customer experiences. Serving various sectors such as education, marketing, retail, and insurance, Sharpen caters to agents, supervisors, IT professionals, and executives, addressing decades-old agent issues responsible for poor customer service.

DRIFT Eyewear Co., established in 2011 and headquartered in Chicago, designs and manufactures eco-friendly eyeglasses. The company offers its products through retailers in the United States, Canada, Australia, and the United Arab Emirates.

Cause.it Inc. is a company based in Indianapolis, Indiana, that specializes in developing mobile applications aimed at enhancing engagement between higher education institutions and their alumni. Founded in 2011, Cause.it provides digital tools that allow schools to connect with graduates by enabling them to create personalized affinity profiles based on their interests. This information helps institutions tailor their engagement strategies and improve their fundraising efforts by moving away from traditional direct mail and telemarketing methods. The platform also facilitates volunteer engagement, offering nonprofits tools to organize service events and communicate effectively with volunteers. By focusing on simplicity and user engagement, Cause.it aims to create a more efficient and effective fundraising experience for both alumni and educational institutions.

Courseload, Inc. is an early-stage educational software company focused on providing digital course materials to students and educators. Its software-as-a-service (SaaS) platform significantly reduces the cost of textbooks and proprietary content by up to two-thirds while ensuring access to self-generated, open source, and fair use educational resources. This affordability can save students thousands of dollars over their undergraduate years, while also enhancing revenue for textbook publishers. The Courseload platform facilitates collaborative teaching and learning, which has been shown to improve educational outcomes through research supported by the National Science Foundation. With a commitment to making higher education more accessible and affordable, Courseload is expanding its services in the K-12 and higher education sectors, partnering with various universities and schools, including multiple Big Ten institutions and community colleges. The company's continued growth reflects its mission to provide significant savings to students while fostering improved learning experiences.

Aarden Pharmaceuticals is a small molecule drug discovery and development company. The company’s novel technology is a chemistry breakthrough that will enable it to make drugs against a previously un-druggable set of intracellular phosphatase (PTP) disease targets. The technology was developed in the laboratory of Dr. Zhong-Yin Zhang, Robert A. Harris Professor and chairman of biochemistry and molecular biology at the Indiana University School of Medicine. Zhang is an internationally recognized expert in the field of protein tyrosine phosphatases (PTPs). Aarden’s first programs are focused on infectious disease, cancer, and metabolic and autoimmune conditions.

Apexian Pharmaceuticals is a clinical-stage biotechnology company developing novel compounds to treat cancer. Its lead drug candidate, APX3330, targets the APE1/Ref-1 redox protein found in many cancers. Founded on Dr. Mark R. Kelley's scientific discoveries at Indiana University School of Medicine, the company aims to safely and effectively treat various diseases.