Nucleus Capital

Nucleus Capital is a Berlin-based venture capital firm founded in 2020 that focuses on supporting purpose-driven entrepreneurs. The firm is dedicated to addressing global challenges related to human and planetary health through entrepreneurial innovation. Nucleus Capital specializes in pre-seed and seed-stage investments, targeting companies in the fields of synthetic and computational biology, food technology, and climate technology. By partnering with founders at the early stages of their ventures, Nucleus Capital aims to foster innovative solutions that contribute to a sustainable future.

Isabella Fandrych

Co-Founder

33 past transactions

AtmoCooling

Pre Seed Round in 2025
AtmoCooling is a company founded in 2022 that focuses on transforming coastal deserts into productive areas for agriculture, clean energy, and climate resilience. Operating in the USA and UAE, the company has developed an innovative evaporated seawater technology that harnesses hot dry winds to create cool microclimates at scale. This technology enables users to cultivate crops effectively, thereby achieving reasonable yields in otherwise harsh environments. By addressing the challenges posed by arid conditions, AtmoCooling aims to foster sustainable development in coastal desert regions.

Spark e-Fuels

Pre Seed Round in 2025
Spark e-Fuels is a climate technology company dedicated to producing sustainable aviation fuels (SAF) aimed at mitigating the environmental impact of aviation. The company addresses challenges related to the limited availability and high costs of SAF by developing integrated production systems that utilize renewable energy, air, and water. Spark e-Fuels employs proprietary, load-flexible processes to ensure scalable and cost-effective production of e-fuels. Through full integration and modularization, their technology allows users to access sustainable aviation fuels at scale, thus promoting carbon-neutral energy solutions for the aviation industry.

AtmoCooling

Pre Seed Round in 2024
AtmoCooling is a company founded in 2022 that focuses on transforming coastal deserts into productive areas for agriculture, clean energy, and climate resilience. Operating in the USA and UAE, the company has developed an innovative evaporated seawater technology that harnesses hot dry winds to create cool microclimates at scale. This technology enables users to cultivate crops effectively, thereby achieving reasonable yields in otherwise harsh environments. By addressing the challenges posed by arid conditions, AtmoCooling aims to foster sustainable development in coastal desert regions.

Ucaneo

Seed Round in 2024
Ucaneo is an environmental services company focused on developing innovative carbon removal technology aimed at capturing carbon dioxide from the atmosphere. The company's approach utilizes a water-based bioreactor equipped with an enzymatically enhanced biomembrane. This technology enables clients to effectively reduce their carbon footprint and contribute to climate change mitigation efforts. Ucaneo's solutions are designed to address the urgent need for sustainable methods to combat rising carbon levels and promote environmental health.

Endolith

Seed Round in 2024
Endolith is a biotechnology company specializing in sustainable mining. It employs microbes, synthetic biology, and cloud computing to extract critical minerals, such as copper, from low-grade ores. Collaborating with leading mining companies, Endolith aims to commercialize its innovative technology, reducing environmental impact and supporting the clean energy transition.

atmio

Pre Seed Round in 2024
Atmio is a climate technology company focused on the oil and gas sector, aiming to address methane emissions through an integrated operating system. The company offers a unique combination of hardware and software solutions designed to help industry operators detect leaks in gas infrastructure, manage the repair process, and report emissions to relevant stakeholders. By providing end-to-end guidance and automation, atmio enables companies to effectively measure and manage their greenhouse gas emissions, contributing to efforts in combating climate change. With its innovative approach, atmio aspires to become a leading provider in the field of emissions management.

Izote Biosciences

Pre Seed Round in 2024
Opeator of a fermentation technology company intended to improve the economics of industrial fermentation. The company develops an anaerobic process that facilitates a more straightforward, more productive fermentation design, its system includes highly predictable performance scaling, the ability to extend fermentation runs for days, and the use of low-cost bioreactors, enabling industries to improve performance and process robustness.

Planet A Foods

Series A in 2024
Planet A Foods is a producer of plant-based, cocoa-free chocolate that focuses on creating food products from natural ingredients. The company emphasizes local production to minimize the impact on land and resources while aiming to reduce global carbon emissions. By utilizing traditional fermentation techniques, Planet A Foods offers an alternative to conventional chocolate, allowing consumers to enjoy chocolate flavors without the associated environmental drawbacks of unsustainable cocoa production.

Trilobio

Seed Round in 2023
Trilobio provides an end-to-end automated platform for synthetic biology and life sciences. It combines robotic lab automation modules with an app store-like environment to package and distribute lab protocols as code, aiming to deploy fully automated laboratories that improve data quality and reproducibility. The platform supports DNA assembly as a service and integrates robotics, software, and genetic engineering, enabling the healthcare industry and other sectors to access automated workflows and reusable biological parts.

Biomia

Pre Seed Round in 2023
Biomia is a synthetic biology company focused on developing plant-derived natural products and novel small molecule therapeutics to treat central nervous system disorders, including pain, addiction, depression, and related neuropsychiatric and neurodegenerative conditions. It uses a drug discovery engine that combines machine learning, biosynthesis, and preclinical testing of nature-inspired molecules to identify safe and efficacious drug candidates and advance them through early development.

Officinae Bio

Seed Round in 2023
Officinae Bio is a biotechnology company focused on revolutionizing the design and development of biological products through advanced computational methods. The company offers a platform that combines experimental protocols, proprietary datasets, and sophisticated design algorithms to enhance the creation of personalized cell therapies and precision fermentation products. Its flagship technologies include Vulcanus, an AI-driven pipeline that automates the construction of complex DNA sequences with a high success rate, and Ulysses, an algorithm designed to navigate the complexities of biological system design. By addressing challenges in DNA synthesis and organism design, Officinae Bio aims to build next-generation bio-foundries that improve scalability, predictability, and purity in microbial production systems, ultimately facilitating the development of innovative bio-based products.

Farmless

Pre Seed Round in 2023
Farmless is a food technology startup developing a fermentation platform that converts renewable-energy feedstocks into carbon-negative, functional proteins and other nutrients, reducing reliance on arable land. By domestifying microbes with food-relevant properties and growing them on liquid feeds powered by renewable energy, it enables scalable, low-cost proteins with a complete amino acid profile while lowering farmers’ carbon footprints. The approach links food production with electricity, creating a new interface between energy and nourishment.

Infyos

Pre Seed Round in 2023
Infyos is a company focused on advancing sustainability within the battery and electric vehicle sectors. It has developed a digital platform that assists battery manufacturers and automotive companies in managing and improving their supply chain sustainability. By providing data-driven insights and actionable solutions, Infyos helps these companies navigate the complexities of sustainability requirements from customers and regulators. The platform serves as a comprehensive resource for understanding and enhancing the battery supply chain, enabling industry players to address challenges and build resilience. With deep domain knowledge and advanced software capabilities, Infyos aims to support the next generation of battery innovators in achieving their sustainability goals. The company is backed by various climate-focused investors.

repath

Pre Seed Round in 2022
Repath is a developer of a climate intelligence platform that focuses on identifying and managing climate risks for companies globally. The company offers a user-friendly, automated Software as a Service (SaaS) solution that forecasts future physical climate risks and assesses the vulnerabilities of assets. Repath's platform translates complex climate data into accessible, aggregated results, allowing users to understand critical elements of their infrastructure or supply chain and implement necessary adaptation measures. By providing climate risk analysis and insights, Repath enables organizations to recognize potential hazards and take proactive steps to mitigate them, thereby enhancing their resilience to climate-related challenges.

Concert Bio

Pre Seed Round in 2022
Concert Bio is a technology company that assists businesses in enhancing their microbial communities' productivity through its proprietary full-stack platform. This platform integrates monitoring, analytics, and intervention strategies to manipulate microbiomes, empowering clients to optimize these communities for improved performance.

Ordinary Seafood

Pre Seed Round in 2022
Ordinary Seafood is a food-tech company focused on creating sustainable seafood alternatives through the use of plant protein and biotechnology. The company aims to address the challenges in the food system by providing delicious and healthy vegan-based seafood products. By leveraging innovative technologies, Ordinary Seafood seeks to offer consumers balanced options that align with their dietary preferences while promoting environmental sustainability.

Go Tiger

Pre Seed Round in 2022
GoTiger is an online supermarket. That offers vegetables, beverages, fruits, meat, rice, noodles, soy, and stir sauces. They also offer gift vouchers.

Planetary

Seed Round in 2022
Planetary is a global infrastructure platform that specializes in the design, construction, and operation of facilities for biomass and precision fermentation. It focuses on producing biotech-enabled alternatives to animal-derived foods at scale, catering to the needs of clients in the bioprocessing and food markets. The company offers a comprehensive range of services, including research and development, upstream processing, and downstream finished product formulations. By leveraging its expertise in engineering and product formulation, Planetary aims to support clients in scaling their operations efficiently while delivering sustainable and diverse food options.

Rhizocore Technologies

Pre Seed Round in 2022
Rhizocore Technologies specializes in the production of locally-adapted mycorrhizal fungi aimed at improving the success rates of tree planting initiatives. By enhancing the natural symbiotic relationships between plants and fungi, the company enables more efficient woodland regeneration and boosts forest productivity. Its innovative platform addresses the needs of the forestry market, allowing for effective reforestation efforts and contributing to the overall health and sustainability of forest ecosystems.

Cirplus

Seed Round in 2021
Cirplus GmbH, founded in 2019 and based in Hamburg, Germany, operates a B2B marketplace focused on recycled plastics. The company has developed an end-to-end trading platform that facilitates the buying and selling of recyclates and plastic waste feedstock globally. By digitizing and streamlining the procurement process, Cirplus addresses the fragmented nature of the plastic recycling industry. Its platform offers a comprehensive solution for customers, enabling them to find, negotiate, contract, ship, insure, and pay for plastic trades seamlessly. Additionally, Cirplus has established an industrial standard for high-quality plastic recycling, enhancing quality control and promoting the use of circular plastics at scale.

Apoha

Pre Seed Round in 2021
Apoha is a stealth stage start-up focused on developing sensory intelligence software that integrates machines with physical reality. The company is creating technology capable of capturing the distinctive sensory fingerprints of complex molecules and formulations. By mapping these materials according to their biophysical properties, Apoha enables the analysis of how different molecules behave, including their bending, rippling, floating, and dissolving characteristics. This innovative approach aims to enhance the interaction between living organisms and their natural environments, facilitating a deeper understanding of complex materials and their behaviors.

Juicy Marbles

Seed Round in 2021
Juicy Marbles is a food-tech company specializing in the production of thick, juicy, and marbled plant-based steaks. Utilizing proprietary protein texturing technology, the company creates whole cuts of plant-based meat designed to closely resemble and taste like traditional animal-derived products. Juicy Marbles aims to provide a diverse range of meat alternatives that match the taste, price, and convenience of conventional meats, thus facilitating a shift towards healthier eating habits. The company's vision includes a commitment to significantly reduce meat consumption by 2030, contributing to a more sustainable future for the meat industry.

Planet A Foods

Seed Round in 2021
Planet A Foods is a producer of plant-based, cocoa-free chocolate that focuses on creating food products from natural ingredients. The company emphasizes local production to minimize the impact on land and resources while aiming to reduce global carbon emissions. By utilizing traditional fermentation techniques, Planet A Foods offers an alternative to conventional chocolate, allowing consumers to enjoy chocolate flavors without the associated environmental drawbacks of unsustainable cocoa production.

Grounded Foods

Seed Round in 2021
Grounded Foods Co. is a West Hollywood-based company that specializes in producing plant-based cheeses crafted from cauliflower and hemp seeds. Founded in 2019 by behavioral economist Veronica Fil and international award-winning chef Shaun Quade, the company employs a proprietary fermentation process that utilizes imperfect vegetables to create products that closely resemble the flavor and texture of dairy cheese. Their product lineup includes gruyere style cheese, camembert style cheese, marinated hemp seed feta, and hemp seed cream cheese, all designed to offer high nutritional value while promoting environmental sustainability. Grounded Foods sells its offerings through both retail stores and online channels, aiming to provide consumers with viable dairy-free alternatives.

Planet A Foods

Pre Seed Round in 2021
Planet A Foods is a producer of plant-based, cocoa-free chocolate that focuses on creating food products from natural ingredients. The company emphasizes local production to minimize the impact on land and resources while aiming to reduce global carbon emissions. By utilizing traditional fermentation techniques, Planet A Foods offers an alternative to conventional chocolate, allowing consumers to enjoy chocolate flavors without the associated environmental drawbacks of unsustainable cocoa production.

Yuri

Seed Round in 2021
Yuri is a company specializing in the design and manufacturing of hardware for the aviation and aerospace industry. It offers a comprehensive range of services aimed at supporting microgravity research and experiments. These services encompass mission definition, hardware selection and development, as well as launch and return logistics. In addition to its focus on space missions, Yuri is involved in various scientific research areas, including growing cell cultures in 3D, modeling human diseases, analyzing proteins and molecules, synthetic biology, studying plant biology, and nanofluidics. This diverse expertise positions Yuri as a key player in advancing research capabilities within the aerospace sector.

Hier Foods

Pre Seed Round in 2021
Hier Foods is a foodtech startup that offers decentralized food systems for retailers and local suppliers. The startup's platform supports all industry-standard EDI integration methods for working with inventory management, as well as a cutting-edge API to make it as simple as possible for IT. Its adaptive software enables even very small suppliers to process digital orders, return shipping notifications and invoices digitally, and easily update prices and products. Instead of faxing, calling, or emailing, they order everything through a single app. Prices, products, and order reminders are always up to date.

Orbillion Bio

Seed Round in 2021
Orbillion Bio, Inc. is a food-tech company based in Fremont, California, focused on developing cultured meat products derived from heritage cattle breeds. Founded in 2019, the company utilizes small tissue samples from high-quality heritage animals to produce premium cell-based meat products. Orbillion Bio aims to harness the potential of cell-cultured meat to provide delicious and nutritious food that is sustainable and accessible. By sourcing heritage cell lines directly from farmers, the company emphasizes a commitment to quality and sustainability in its production processes.

Hoxton Farms

Seed Round in 2021
Hoxton Farms, based in London, UK, specializes in producing real animal fat without the use of animals. The company employs cell biology and advanced mathematical modeling to cultivate purified animal fat in bioreactors, catering primarily to the meat alternatives industry. This innovative approach enables the creation of cruelty-free fat that can be utilized not only in meat alternatives but also in other sectors such as bakery, confectionery, and cosmetics. By focusing on sustainable and ethical production methods, Hoxton Farms aims to transform the way fat is sourced and used in various products.

Vosbor

Series A in 2021
Vosbor is a global digital marketplace specializing in the trade of bulk agricultural commodities, including corn, wheat, soybeans, and palm oil, among others. Established in 2019 and headquartered in Amsterdam with additional offices in Singapore, Vosbor facilitates international trade logistics and settlement through its advanced trading platform, which is built on blockchain technology. This innovative approach allows for secure data reconciliation and the sharing of documents through smart contracts, ensuring transparency and efficiency in the trading process. By connecting buyers and sellers, Vosbor aims to streamline the execution of trade, finance, and shipping within the agricultural sector.

Cirplus

Pre Seed Round in 2020
Cirplus GmbH, founded in 2019 and based in Hamburg, Germany, operates a B2B marketplace focused on recycled plastics. The company has developed an end-to-end trading platform that facilitates the buying and selling of recyclates and plastic waste feedstock globally. By digitizing and streamlining the procurement process, Cirplus addresses the fragmented nature of the plastic recycling industry. Its platform offers a comprehensive solution for customers, enabling them to find, negotiate, contract, ship, insure, and pay for plastic trades seamlessly. Additionally, Cirplus has established an industrial standard for high-quality plastic recycling, enhancing quality control and promoting the use of circular plastics at scale.

Magmatic Bio

Magmatic Bio is a company that specializes in developing innovative metal separation processes. It leverages the power of biological systems, specifically metal-binding proteins, to create robust, reusable, and highly selective solutions for metal recovery. The company's technology aims to reduce energy, water, and toxic reagent consumption, making it a more sustainable and efficient alternative to traditional methods. Magmatic Bio's ultimate goal is to create scalable and reliable processes that can be integrated into various industries, contributing to a more circular economy.
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