Kairos Ventures

Vivodyne develops an automated robotic system that discovers life-changing drugs and cellular therapies. Its platform cultures human tissues in labs for realistic preclinical drug testing, using advanced AI to accelerate the creation of safe and effective therapeutics.

Founded in 2017, PteroDynamics aims to enhance mobility while minimizing environmental impact through sustainable autonomous vertical takeoff and landing (VTOL) aircraft. Its patented Transwing design enables wings to fold during flight, offering advantages over traditional VTOL designs for both cargo and passenger transport.

Behavioral Signals develops AI-driven technology that analyzes human behavior from voice data. Their flagship product, AI-MC, helps businesses optimize call center conversations by automatically matching customers with suitable agents based on voice data and emotion analysis, enhancing profitability.

Tulu is an on-demand rentals platform that provides household and lifestyle products through its application and IoT-enabled smart rental units installed in buildings. Based in Tel Aviv, Israel, it offers residents, students, and offices access to brand-name appliances, grocery staples, micro-mobility and entertainment devices on demand, with the aim of optimizing space usage and reducing waste. The platform analyzes usage data to improve inventory management and personalize the user experience. Tulu operates in cities across the United States and Europe, working with large landlords and real estate partners, and collaborates with manufacturers such as Bosch, Hoover, Kärcher and Unagi to deliver a broad range of items.

Vivodyne develops an automated robotic system that discovers life-changing drugs and cellular therapies. Its platform cultures human tissues in labs for realistic preclinical drug testing, using advanced AI to accelerate the creation of safe and effective therapeutics.

AetherTouch is a technology company specializing in acoustic wave technology aimed at enhancing interaction with electronic devices. The company develops a software development kit that enables new applications to be integrated directly into operating systems, allowing for innovative control mechanisms without the need for touch screens. AetherTouch's technology utilizes advanced signal processing algorithms to leverage the unique characteristics of acoustic signals, providing precise 2D tracking for devices such as smartphones, tablets, and computers. This approach not only improves user experience but also addresses concerns related to power consumption and privacy that are often associated with conventional camera-based systems. Additionally, AetherTouch supports scientists in commercializing their technological advancements, fostering innovation in the industry.

Novosteo Inc. is a biotechnology company based in West Lafayette, Indiana, founded in 2017. The firm specializes in developing and manufacturing innovative drugs aimed at healing bone fractures and addressing related conditions that significantly impact patients' morbidity, mortality, and quality of life. With scientific guidance from co-founders Stewart Low and Philip Low of Purdue University, Novosteo utilizes a proprietary chemistry approach to bone targeting, which allows for the delivery of anabolic agents directly to fracture surfaces. This unique method focuses on accelerating bone regeneration and improving healing outcomes, thereby mitigating the debilitating effects associated with bone injuries and enhancing patient mobility and productivity.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

Anycart is a meal discovery and grocery shopping platform that simplifies the cooking process for users by integrating meal planning with grocery shopping. The application allows users to search for meals they wish to prepare, provides relevant recipes, and adds the necessary ingredients to their preferred grocery delivery service. It further enhances the cooking experience by offering step-by-step video instructions for each recipe. Founded in 2019 during the Amazon Alexa Accelerator and now based in Palo Alto, California, Anycart aims to make meal planning accessible and affordable, helping users efficiently utilize their grocery purchases by suggesting additional recipes that can use leftover ingredients.

Founded in 2013, Foldax designs and manufactures synthetic heart valves using life polymer technology. Its products aim to provide artificial blood pumping support for patients with aortic, mitral, or tricuspid valve disease via percutaneous or surgical delivery.

Specter Aerospace develops innovative solutions for plasma-assisted combustion, aiming to reduce fuel consumption and emissions while expanding operational limits of advanced engines. Their primary focus is on hypersonic vehicles designed to improve combustion efficiency across energy, aerospace, and national security sectors.

Founded in 2018, Turbodega is a Peruvian company that develops a mobile application platform for retailers and distributors. Its AI-powered platform automates orders, optimizes inventory, and tracks daily sales in real-time, digitizing and optimizing supply chains.

Actinia develops advanced radiation detection technology using perovskite-based materials. These materials demonstrate superior X-ray sensitivity and gamma-ray energy resolution, enabling clients in nuclear energy, non-proliferation, and medical imaging sectors to access enhanced detector technologies.

Founded in 2017, PteroDynamics aims to enhance mobility while minimizing environmental impact through sustainable autonomous vertical takeoff and landing (VTOL) aircraft. Its patented Transwing design enables wings to fold during flight, offering advantages over traditional VTOL designs for both cargo and passenger transport.

Pinpoint Therapeutics is a preclinical-stage company developing novel cancer therapies that inhibit autophagy, a key cell survival and treatment-resistance pathway. It designs autophagy inhibitors that target the PPT1 enzyme, which is highly expressed across most cancers, with the aim of overcoming therapy resistance and broadening treatment options either as standalone therapy or in combination.

GuRu Wireless, Inc. enables safe, effective and customizable transmission of power over-the-air using proprietary millimeter-wave (mmWave) integrated circuits, modules and proprietary Smart RF Lensing technology. A miniature-sized power transfer system delivers power at an unprecedented distance efficiently and with precision. GuRu's wireless solution can be used as a charging hub or a power source in many settings where access to an energy source is needed. It is easy to install, safe, and sophisticated enough to find and adjust for various power levels to sync with the needs of any device. Even during use, it continuously charges devices and as a safety measure, reroutes power as necessary. Founded in 2017 by a team of scientists and engineers from Caltech, GuRu aims to ensure access to power be as ubiquitous as WiFi.

Actuate Therapeutics is a clinical-stage biopharmaceutical company focused on discovering and developing therapies that inhibit glycogen synthase kinase-3 beta (GSK-3β) to treat cancer and neurodegenerative diseases. The company is advancing elraglusib (formerly 9-ING-41), a small-molecule GSK-3β inhibitor designed to disrupt signaling pathways that support tumor cell survival, growth, migration and invasion, with activity reported in challenging cancers such as glioblastoma, pancreatic, ovarian, and breast cancers. Actuate Therapeutics pursues combination approaches and aims to bring new agents to clinical development. Established in 2015, the company is based in Fort Worth, Texas, with an additional office in Dublin, Ireland.

MixComm Inc. is a fabless semiconductor company based in Chatham, New Jersey, specializing in wireless technology solutions for a range of applications. Founded in 2017, the company develops advanced semiconductors for communications in smartphones, laptops, Wi-Fi routers, smart TVs, game consoles, virtual-reality headsets, and radar systems used in vehicles and defense electronics. Utilizing RFSOI process technology, MixComm focuses on creating millimeter-wave products that enhance performance and integration for 5G infrastructure and satellite communication. The company provides application-specific chips designed to meet the needs of various electronic components, facilitating innovative advancements in wireless communications technology.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

Linnaeus Therapeutics is a development-stage biotechnology company focused on identifying and advancing small molecule therapeutics that modulate cellular differentiation to treat cancer and pigmentation disorders. Based in Haddonfield, New Jersey, the company originated as a Penn Center for Innovation UPstart venture founded on discoveries from the Ridky laboratory at the University of Pennsylvania and was established around 2015–2016. Its molecular agents are designed to influence melanin production in skin cells, enabling treatment of cancers and pigmentation disorders driven by oncogenic mutations.

New Age Meats is a biotechnology company based in San Francisco, California, founded in 2017. The company specializes in producing cultivated meat through an innovative automated, data-driven platform that utilizes stem cell technology. By growing meat from animal cells instead of relying on traditional animal slaughter, New Age Meats aims to create healthier and more sustainable food options.

kencko is a company that produces and sells organic fruit and vegetable products in the United States, United Kingdom, and Canada, including sachet-based drinks sold in various pack sizes. Founded in 2017 and based in New York, with a processing facility in Lisbon, Portugal, kencko aims to make organic produce convenient without sacrificing freshness. Its product line centers on instant smoothies and sachet drinks that add organic fruits and vegetables to the daily routine, without added sugar, chemicals, or colorants, preserving the nutritional content for home preparation. The company positions its offerings as a convenient alternative to fresh produce, enabling hassle-free consumption of healthy smoothies and beverages.

Actuate Therapeutics is a clinical-stage biopharmaceutical company focused on discovering and developing therapies that inhibit glycogen synthase kinase-3 beta (GSK-3β) to treat cancer and neurodegenerative diseases. The company is advancing elraglusib (formerly 9-ING-41), a small-molecule GSK-3β inhibitor designed to disrupt signaling pathways that support tumor cell survival, growth, migration and invasion, with activity reported in challenging cancers such as glioblastoma, pancreatic, ovarian, and breast cancers. Actuate Therapeutics pursues combination approaches and aims to bring new agents to clinical development. Established in 2015, the company is based in Fort Worth, Texas, with an additional office in Dublin, Ireland.

Xidas designs and manufactures micro-scale sensing and actuation solutions for IoT, industrial, and life-technology applications. The company utilizes a patented miniaturization paradigm called Amalga, which blends novel manufacturing methods, design approaches, and diverse materials to create integrated micro-sensors, micro-actuators, 3D microstructures, and related substrates and assemblies. It employs non-silicon manufacturing processes to produce microelectronics substrates, 3D structures, and printed circuit boards, enabling compact, energy-efficient modules suitable for healthcare, biotech, medical devices, and a range of industrial IoT scenarios. By combining multidisciplinary expertise and a toolbox of precision fabrication, Xidas delivers industry-first smart modules and sensors designed to simplify process monitoring and control across various markets.

Founded in 2009, Transient Plasma Systems develops and manufactures pulsed power systems for various industries. Its core technology involves ultra-fast, high-voltage electrical pulses that deliver high peak power using minimal energy, enabling efficient combustion processes across sectors such as automotive, defense, aerospace, heavy transport, energy, medicine, and agriculture.

Stoicheia is a nanotechnology company accelerating materials discovery by defining and expanding the materials genome. Using its proprietary lithography technology, Stoicheia has developed a way to create Megalibraries of nanomaterials on a chip. The company's technology also can be used to combine elements in new ways — already creating structures comprising up to seven elements.

Siege Pharmaceuticals is a biopharmaceutical company focused on developing innovative cancer therapies that leverage a naturally occurring molecule to effectively starve cancer cells. The company creates synthetic variants of this molecule, which possess optimized drug-like properties and target various pathways essential for cancer cell growth. By inhibiting these pathways, Siege Pharmaceuticals aims to prevent the development of resistance in cancer cells, thus providing medical practitioners with tools to better control the progression of the disease. The company’s approach is designed to enhance treatment efficacy and improve patient outcomes in the fight against cancer.

NVasc is an early-stage ophthalmology company with a focus on treating blindness. It specializes in treating the leading causes of blindness through choroidal and retinal revascularization. The company has acquired the research rights to growth factors (NVB001 and NVB002) that have been shown to encourage the growth of non-leaking new vessels in the retina and choroid in mouse models of ischemic eye diseases. The company is planning to manufacture NVB001 which can be used in toxicokinetic studies and in early clinical trials in humans.

Linnaeus Therapeutics is a development-stage biotechnology company focused on identifying and advancing small molecule therapeutics that modulate cellular differentiation to treat cancer and pigmentation disorders. Based in Haddonfield, New Jersey, the company originated as a Penn Center for Innovation UPstart venture founded on discoveries from the Ridky laboratory at the University of Pennsylvania and was established around 2015–2016. Its molecular agents are designed to influence melanin production in skin cells, enabling treatment of cancers and pigmentation disorders driven by oncogenic mutations.

LifeSprout is developing the next generation of synthetic soft tissue substitutes for aesthetic and reconstructive medicine. They offer revolutionary products for aesthetic and regenerative medicine. They have created a platform that looks and behaves like the body’s own tissues. The company is turning this into a suite of products for millions of patients each year with soft tissue losses from aging, cancer, and metabolic disease.

PolyCera, Inc. specializes in the development and manufacturing of advanced ultrafiltration membranes made from organic polymer materials. Founded in 2012 and based in Los Angeles, California, the company offers products such as the PolyCera hydro, a sub-20 nm membrane effective in removing bacteria, viruses, and protozoa, and the PolyCera titan, a sub-5 nm membrane known for its stability in challenging conditions including extreme pH, temperature, and fouling. These membranes feature a unique Spiral Monolith design that combines the advantages of polymeric, tubular, and ceramic membranes, resulting in high permeability and reduced operational costs. PolyCera membranes are oleophobic and hydrophilic, allowing for easy backwashing, which minimizes downtime and the need for cleaning chemicals. With a current installed capacity exceeding 55 million gallons per day, PolyCera membranes are utilized in various sectors, including clean energy, industrial wastewater management, and municipal water treatment. The company was acquired in 2020 by PSP.US, Inc., which continues to market its innovative filtration products under the PolyCera brand.

nFugue is building on the groundbreaking work developed at Caltech to open a new level of nano-architected materials that can be used for a wide variety of applications, from tiny medical implants to ultra-lightweight impact-resistant fabrics or textiles to ultra-lightweight aircraft components. The revolutionary process will reduce the size of the 3D printed structures by 5x while enabling a whole new set of unprecedented combinations of properties, for example, ultra-lightweight; thermally insulating; strong, stiff, and low-density; and impact-absorbing.

Tanvas develops Surface Haptics technology for touchscreens, creating variable friction using electrostatic fields. This enables users to feel what they see on a screen, enhancing interaction beyond visual and vibration feedback.

Keren Therapeutics is harnessing the biology of a naturally occurring peptide hormone to restore muscle function in the context of several musculoskeletal and muscle wasting diseases. Using the same biological insights, Keren is also developing a therapeutic to counteract cognitive decline associated with age-related neurodegenerative conditions.

Founded in 2013, DigitalGenius develops AI-powered software solutions for enhancing customer service operations. Its platform uses advanced AI technologies like conversational AI and visual recognition to automate and optimize customer interactions across multiple channels, ensuring efficient resolution of inquiries.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

1200 Pharma is a biotechnology company focused on accelerating pre-clinical drug discovery and clinical approval processes. Utilizing innovative medicinal chemistry technology developed at Caltech alongside proprietary biomarker-driven assays from UCLA, the company aims to streamline the drug development timeline. By integrating UCLA's advanced drug screening tools with Caltech's cutting-edge chemistry research, 1200 Pharma identifies promising therapeutic targets that enhance the likelihood of clinical success. This platform enables researchers to create proprietary drugs with distinct and optimized profiles, ultimately advancing the field of drug development.

Symbiotix Biotherapies is a biotechnology company focused on developing a novel class of molecular therapeutics aimed at treating inflammatory bowel disease, multiple sclerosis, and other serious immune-mediated conditions. The company's therapeutics are based on molecules derived from the human microbiome, allowing for the creation of first-in-class oral agents. These innovative treatments are designed to empower patients to manage their health more effectively and improve their quality of life. By harnessing the therapeutic potential of the microbiome, Symbiotix Biotherapies seeks to address significant unmet medical needs in the field of immune-mediated diseases.

MixComm Inc. is a fabless semiconductor company based in Chatham, New Jersey, specializing in wireless technology solutions for a range of applications. Founded in 2017, the company develops advanced semiconductors for communications in smartphones, laptops, Wi-Fi routers, smart TVs, game consoles, virtual-reality headsets, and radar systems used in vehicles and defense electronics. Utilizing RFSOI process technology, MixComm focuses on creating millimeter-wave products that enhance performance and integration for 5G infrastructure and satellite communication. The company provides application-specific chips designed to meet the needs of various electronic components, facilitating innovative advancements in wireless communications technology.

Diabetic Retinopathy is the leading cause of vision loss in adults worldwide. Opera Therapeutics is developing treatments based on technology from Columbia University that harnesses a natural cellular mechanism to prevent the damage and cell death that are hallmarks of Diabetic Macular Edema (DME) and Retinal Vein Occlusion (RVO) which account for the majority of vision loss amongst people with diabetes. Unlike currently available anti-angiogenesis therapies which are injected directly into the eye, carry the risk of thromboembolic side effects, and are frequently ineffective, Opera Therapeutics is developing a biologic with a unique mechanism of acting for topical administration as an eye-drop, and aims to bring enhanced relief to patients suffering from diabetic retinopathy without the requirement for regular interocular injections. Opera Therapeutics is additionally exploring the utility of their biologics for treating stroke-induced edema in the brain.

Sienza Energy develops rechargeable battery technology based on a three-dimensional nanotechnology electrode structure that leverages advances across multiple fields to create batteries with higher energy and power densities while reducing overall costs. The company’s approach aims to deliver broader capability for products ranging from smart devices to electric vehicles.

Repairogen is a biotechnology company focused on anti-aging skincare ingredients and products, developing premium formulations based on proprietary DNA-repair technology derived from a platform created at a leading Ivy League medical research institution. Founded in 2012 and headquartered in New York, the company targets DNA damage-related skin aging and disease, with products designed to reduce DNA damage in skin cells after UV exposure to improve skin health and appearance.

GuRu Wireless, Inc. enables safe, effective and customizable transmission of power over-the-air using proprietary millimeter-wave (mmWave) integrated circuits, modules and proprietary Smart RF Lensing technology. A miniature-sized power transfer system delivers power at an unprecedented distance efficiently and with precision. GuRu's wireless solution can be used as a charging hub or a power source in many settings where access to an energy source is needed. It is easy to install, safe, and sophisticated enough to find and adjust for various power levels to sync with the needs of any device. Even during use, it continuously charges devices and as a safety measure, reroutes power as necessary. Founded in 2017 by a team of scientists and engineers from Caltech, GuRu aims to ensure access to power be as ubiquitous as WiFi.

Founded in 2009, Transient Plasma Systems develops and manufactures pulsed power systems for various industries. Its core technology involves ultra-fast, high-voltage electrical pulses that deliver high peak power using minimal energy, enabling efficient combustion processes across sectors such as automotive, defense, aerospace, heavy transport, energy, medicine, and agriculture.

Chimera Bioengineering develops engineered cell therapies to enhance the body's ability to fight cancer. The company focuses on chimeric antigen receptor (CAR) T-cell approaches and aims to redesign the immune response to overcome cancer’s ability to evade detection. Its technology uses drug-responsive gene regulators to reprogram the software of the immune system, with the goal of minimizing toxicity, increasing efficacy, and extending CAR-T cell persistence. This approach seeks to improve safety and effectiveness for patients with cancers that are difficult to treat, including liquid tumors and certain solid tumors. Chimera Bioengineering develops therapies intended to boost T-cell recognition and tumor targeting, enabling longer-lasting, personalized treatments for advanced cancers. Through research and development, the company aims to broaden the impact of cell therapies beyond current options and move toward cures for patients unresponsive to standard therapies.

DEARHealth is a health technology company based in Beverly Hills, California, founded in 2013. It specializes in developing a Software as a Service (SaaS) based healthcare management platform tailored for medical providers and health insurers. The company leverages advanced data analytics to create disease-specific, coordinated care pathways that enhance provider workflows, support organizational decision-making, and engage patients through dedicated apps. DEARHealth's solutions are designed to improve health outcomes and experiences for chronically ill patients while reducing costs, with a focus on value-based healthcare.

NanoClear Technologies is a Los Angeles-based startup specializing in nanotechnology for surface modification. Founded by alumni from prestigious institutions like JPL/NASA, Caltech, UC Berkeley, UCLA, and MIT, the company holds proprietary technology capable of altering the wettability of any arbitrary surface. Their primary applications include anti-fogging solutions for consumer wearables and anti-frost performance in industrial settings, with potential use cases across automobile, aerospace, and solar panel industries.

Actinobac Biomed, Inc. is a biopharmaceutical company based in Kendall Park, New Jersey, founded in 2009. The company specializes in developing therapeutics for a range of medical conditions, including blood cancers, autoimmune and inflammatory diseases, and HIV. Its lead product, Leukotoxin, is a bacterial toxin that specifically targets and eliminates white blood cells, making it a promising candidate for treating hematologic malignancies such as leukemia and lymphoma. In addition to its primary focus on blood cancers, Actinobac Biomed is exploring the use of Leukotoxin and its derivatives for treating infectious diseases like HIV/AIDS and tuberculosis, as well as various autoimmune disorders, including rheumatoid arthritis and psoriasis. The company is committed to advancing its drug candidates through a strategic approach that prioritizes hematologic malignancies while also fostering early-stage drug discovery programs to maintain a robust pipeline of novel therapeutic agents.

3D Bio Holdings is a biotechnology company specializing in bioprinting technologies to create patient-specific living tissues for surgical healing. Founded in 2014, the company is headquartered in Brooklyn, New York, with an additional office in New York City. Utilizing proprietary technologies such as GMPrint and ColVivo, 3D Bio Holdings aims to address the limitations of the body's natural healing processes by providing therapeutic solutions for various diseases and congenital medical conditions.

Holoclara is an immunotherapy company focused on providing innovative solutions for individuals suffering from autoimmune disorders. The company specializes in delivering nematode-derived molecules known for their therapeutic properties. By identifying and developing these molecules from various worm species, Holoclara aims to create safe, orally available therapeutics that can improve the quality of life for patients. Through its targeted approach, Holoclara seeks to bring relief and promote overall health and well-being for those affected by autoimmune conditions.

Neuro-Bio is a start-up company dedicated to creating innovative therapeutics for neurodegenerative disorders, including Alzheimer's, Parkinson's, and Motor Neuron Disease. The company distinguishes itself through its pioneering approach to identifying the initial triggers of neurodegeneration, a concept developed by Baroness Professor Susan Greenfield over her 40-year career in neuroscience. Neuro-Bio focuses on the discovery and development of oral medications and biomarkers that identify novel amino acid bioactive peptides, offering physicians a more effective strategy for treating these debilitating conditions. Through its research and development efforts, Neuro-Bio aims to address the critical need for effective therapies in the field of neurodegeneration.

Amorphology is a manufacturer specializing in the production of lightweight metallic parts, utilizing advanced metal alloy technologies and innovative production techniques. The company focuses on creating specialty gears tailored for non-commercial robotics applications, particularly precision gearboxes designed for collaborative robots. By enhancing the performance, durability, elasticity, and wear resistance of these components, Amorphology aims to contribute to the advancement of robotic systems across various industries. Through its commitment to material innovation, the company seeks to deliver high-quality solutions that meet the evolving demands of the robotics sector.

Behavioral Signals develops AI-driven technology that analyzes human behavior from voice data. Their flagship product, AI-MC, helps businesses optimize call center conversations by automatically matching customers with suitable agents based on voice data and emotion analysis, enhancing profitability.

Axial Biotherapeutics, Inc. is a biopharmaceutical company focused on developing therapeutics for central nervous system (CNS) diseases and disorders. Utilizing a microbiome discovery platform, the company targets the gut-brain axis to create innovative therapies aimed at improving the quality of life for patients suffering from neurological conditions. Founded in 2013 and headquartered in Waltham, Massachusetts, Axial Biotherapeutics is in the clinical stage of its development, working to advance its pipeline of novel CNS therapeutics.

Axial Biotherapeutics, Inc. is a biopharmaceutical company focused on developing therapeutics for central nervous system (CNS) diseases and disorders. Utilizing a microbiome discovery platform, the company targets the gut-brain axis to create innovative therapies aimed at improving the quality of life for patients suffering from neurological conditions. Founded in 2013 and headquartered in Waltham, Massachusetts, Axial Biotherapeutics is in the clinical stage of its development, working to advance its pipeline of novel CNS therapeutics.

Gene Sciences, Inc. is a biotechnology company based in San Diego, California, incorporated in 2016. The company focuses on the development of innovative DNA-targeted therapeutics aimed at modulating gene expression for the treatment of various human diseases. Gene Sciences serves customers primarily in the United States and is dedicated to advancing solutions that address unmet medical needs through its proprietary therapeutic approaches.

MemiRay, LLC is a health technology company based in Arcadia, California, founded in 2016. The company specializes in developing personal health monitoring devices, notably the InstaPath, which measures multiple human fluid analytics simultaneously. This device targets critical health concerns such as Diabetes Mellitus and Coronary Heart Disease while also monitoring personal hydration levels. MemiRay's innovative approach focuses on convenience and ease of use, facilitating improved regimen adherence and overall health management. Additionally, the company offers cloud-based informatics software designed to ensure data integrity, security, and precise time stamping for health-related data. MemiRay serves a diverse clientele, including individuals and various healthcare entities such as hospitals, health care centers, and pathology facilities, aiming to simplify health monitoring and enhance therapeutic outcomes.

KMLabs specializes in manufacturing advanced laser systems for research and industrial applications. It focuses on the development and delivery of optimized tabletop ultrafast laser sources, spanning the VUV to soft X-ray range (1-200 nm) at femtosecond/attosecond timescales.

Applaud Medical, Inc. is a medical device company based in San Francisco, California, focused on developing and commercializing innovative treatments for kidney stones, a condition affecting over 2 million individuals annually in the United States. Established in 2014, the company aims to address the limitations of existing treatments, which often require anesthesia and are only partially effective. Applaud Medical's novel approach will enable urologists to treat kidney stones measuring between 5 to 15 millimeters through a simple outpatient procedure, significantly improving patient outcomes and convenience.

Compellon, Inc. is a data analytics software company based in Laguna Hills, California, founded in 2010. It specializes in providing prescriptive analytics solutions to industries such as healthcare, financial services, and advertising. Compellon's product offerings include Iris Pro, an analytics advisory tool; Compellon 20|20, a clear-box analytics platform; and 20|20 Survey, a survey analytics solution. The company's innovative approach leverages advanced information theory and artificial intelligence to deliver actionable insights rapidly, allowing organizations to optimize outcomes efficiently. Compellon’s technology empowers business analysts by eliminating the need for extensive technical expertise, enabling them to make intelligent, data-driven decisions in real time. By focusing on complete business problems and providing strategic and tactical prescriptive actions, Compellon enhances the ability of organizations to respond effectively to dynamic competitive environments and complex data challenges.

Delpor is a San Francisco-based developer of drug delivery technologies focused on creating sustained and pattern-specific release of proteins, peptides, and small molecules through small, non-mechanical subcutaneous implants. Its platforms include Prozor, a non-mechanical implantable device for delivering antipsychotics and other small molecules; NANOPOR, a membrane architecture-based implant offering prolonged release; and Delos PUMP, a self-contained implant that delivers drugs in programmed or pulse patterns, with potential for external activation to provide episodic dosing of therapies such as pain medications, antidotes, stimulants, or resuscitation agents. Founded in 2009, the company aims to improve medication adherence, safety, and efficacy by enabling convenient in-office implantation and simple administration, reducing the need for frequent injections. Delpor seeks to partner or license its technologies to advance long-acting formulations and pattern-specific dosing across therapeutic areas.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

Vivodyne develops an automated robotic system that discovers life-changing drugs and cellular therapies. Its platform cultures human tissues in labs for realistic preclinical drug testing, using advanced AI to accelerate the creation of safe and effective therapeutics.