University of Massachusetts Amherst is a public research and land-grant university that offers academic, master's, and doctoral programs. It is the flagship campus of the University of Massachusetts system. University of Massachusetts Amherst has an annual enrollment of approximately 1,300 faculty members and more than 30,000 students.
Operator of a near-commercial stage company intended to develop non-invasive systems for the treatment of serious neurological disorders. The company's platform is based on neuronal hyperexcitability suppression, they are initially applying their multi-site, precision-targeted neuromodulatory approach to stroke and ALS (amyotrophic lateral sclerosis) and are manufacturing a non-invasive device for the treatment of post-stroke spasticity, and represents a novel, non-invasive targeted-neuromodulation platform to regulate motor neuron excitability, enabling patients to receive treatment without the need for drugs or surgery.
Kytopen Corp. is a biotechnology company based in Cambridge, Massachusetts, focused on advancing cell therapy through its innovative Flowfect technology. Established in 2017, Kytopen specializes in non-viral delivery systems for molecules into challenging immune cells that are typically hard to transfect. The company utilizes a combination of microfluidics and automation to streamline the delivery process, making it faster, more efficient, and cost-effective. By employing a unique platform that integrates continuous fluid flow with electric fields, Kytopen enables researchers to produce high-quality engineered cells in a matter of minutes while preserving their health and functionality. This approach supports the discovery of novel biological insights and the development of affordable cell and gene therapies.
InstantEye Robotics is a division of Physical Sciences Inc., both located in Andover Massachusetts, approximately a half-hour north of Boston. InstantEye Robotics’ tactical, unmanned aerial systems (UAS) are the systems of choice by the military, law enforcement, first responder, and commercial users around the world. Our products are characterized by their affordability, ruggedness, and ease of use. We provide full-spectrum solutions, from initial concepts through to products manufactured in our state-of-the-art production facility.
Make your future more predictable See the signals, ignore the noise
Worcester Polytechnic Institute (WPI), founded in 1865, is a non-profit educational institution located in the United States. It provides a diverse range of undergraduate and graduate programs, including fields such as computer science, chemical engineering, psychology, and business administration. WPI is known for its distinguished faculty, advanced research facilities, and an active community that fosters collaboration and innovation. The institute emphasizes a hands-on approach to learning, encouraging students to engage in real-world problem-solving and make meaningful contributions to society.
Harvard College, established in 1636 and located in Cambridge, Massachusetts, is a prestigious educational institution that offers a comprehensive array of academic programs across disciplines such as arts and humanities, sciences, social sciences, and engineering. It emphasizes excellence in teaching, learning, and research, fostering the development of leaders who impact the global community. The college supports its students with access to advanced technological resources for research and a significant financial aid program, which allocates over $160 million to assist more than 60% of undergraduates. Harvard University, of which Harvard College is a part, is the oldest institution of higher education in the United States and serves over 20,000 degree candidates across its twelve schools and the Radcliffe Institute for Advanced Study. Harvard Management Company, founded in 1974, manages the university’s endowment and financial assets, investing in various markets while employing external managers for its portfolio.
FLxDER creates a prototype of its cloud-based software to optimize electric fleet vehicle charging so as to reduce electric grid impacts and costs, and coordinate operation with other distributed energy resources.
Altus Thermal, founded in 2019 and based in Boston, Massachusetts, focuses on transforming thermal energy solutions for residential settings. The company aims to enhance efficiency, comfort, and user experience while providing benefits to the electrical grid. Altus Thermal develops energy technology designed to electrify residential heating, cooling, and hot water systems. By maximizing performance and facilitating better integration with renewable energy sources and other distributed energy resources, the company enables homeowners to electrify their living spaces in an efficient and cost-effective manner.
Realtime Robotics, Inc. specializes in developing motion planning and control processors that empower robots and vehicles to swiftly respond to their surroundings. Founded in 2016 and based in Boston, Massachusetts, the company offers a collision-free motion planning platform that adapts to changes in work environments, allowing for the safe operation of single or multiple robots in unstructured settings. Its RapidPlan processor utilizes advanced computer processing and software to eliminate the trade-off between speed and safety in automation, enabling machines to generate safe motion plans in milliseconds. This innovation facilitates collision avoidance around both static and dynamic objects, while performing various tasks in diverse locations. Realtime Robotics aims to transform automation across industries and enhance the functionality of autonomous vehicles, promoting broader applications and faster adoption of robotics technology.
Blue Therapeutics was founded in 2014 by Ajay Yekkirala, David Roberson, Michio Painter and academic founder Phil Portoghese. Blue was born out of the desire to take decades of knowledge and technology from academic research and transform that work into therapeutic solutions that can have positive and lasting impacts for patients in the clinic. Working in New England where the opioid epidemic has struck particularly hard, this meant asking theirselves why better therapeutic options for pain don't exist.
Kinto.Care is a provider of an online platform intended to improve communication and provide practical advice for caregivers. The company's platform features user-generated content and digital tools to improve care team collaboration, medication management and check-in data tracking, enabling the family members of a patient to coordinate care and manage medicines through a single platform.
PlenOptika, Inc. is a Massachusetts-based company that develops innovative optical technology to improve eye care accessibility. It manufactures a handheld device called QuickSee, which provides accurate refractive measurements for eyeglass prescriptions at the push of a button. This device is especially beneficial in rural and low-resource settings, addressing the vision needs of over one billion people globally. PlenOptika originated from research initiatives at the Massachusetts Institute of Technology and the Madrid–MIT M+Visión Consortium, where its founders aimed to tackle low vision issues through biomedical innovation. The company has received recognition from social innovation foundations and has collaborated with research centers in the United States, Spain, and India to refine its technology. By reducing the cost and space requirements of traditional autorefractors, PlenOptika enables more efficient and accessible eye care solutions for underserved communities.
Pison is a human performance company focused on enhancing cognitive and physiological capabilities through gesture control technology. The company develops a wearable technology that utilizes patented electroneurography to create a gesture-controlled ecosystem. Its advanced biopotential sensor allows for highly sensitive interaction in various applications, including virtual reality, full-body prosthetics, and exoskeletons. By integrating hardware, software, and machine learning, Pison aims to transform human-computer interaction, thereby improving users' quality of life. The company collaborates with notable partners and investors, including Special Forces, the Air Force, and NASA.
MSW Power Corporation, established in 2012 and based in Acton, Massachusetts, specializes in waste management solutions. The company offers innovative products such as the BWEC GEM, an integrated system that transforms various types of waste—including paper, wood, plastic, agricultural residues, and food—into electricity and heat. Additionally, MSW Power provides the HydroPactor, which efficiently reduces the weight of waste by extracting moisture, and a solid waste destruction system that utilizes mechanical and thermal methods to remove moisture from solid waste. Through these technologies, MSW Power aims to deliver environmentally beneficial and economically viable solutions for energy and waste management.
SICdrone is an aerospace company based in Portland, Oregon, that specializes in the manufacture of high-speed, high-stability tilt rotor drones designed for commercial applications. Founded in 2016, the company focuses on creating all-weather aerial flight systems capable of conducting structural and energy asset inspections, as well as aerial operations in challenging environments. These drones are engineered for maximum flight efficiency and enhanced mission capabilities, approaching speeds close to the FAA limit of 100 mph. SICdrone has established partnerships with various organizations to support projects in government, security, and agriculture, making it a key player in the drone services sector. The company also offers modular and interchangeable camera systems, facilitating aerial imaging and mapping for defense agencies.
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
NanoView Biosciences is a biotechnology company based in Boston, Massachusetts, specializing in the characterization of extracellular vesicles, particularly exosomes. Utilizing its proprietary ExoView technology, the company provides high-throughput, cost-effective analysis solutions that facilitate the detection and multiparametric characterization of exosomes from complex biological samples such as whole blood, serum, plasma, and urine. NanoView Biosciences offers a range of products, including the ExoView R100 and ExoView Tetraspanin, as well as custom assays and sample services. The company's innovations support research and the advancement of precision medicine, enabling life science researchers to gain insights into the biological roles of exosomes as potential biomarkers for disease diagnosis, treatment, and monitoring. Founded in 2015, NanoView Biosciences is committed to enhancing the understanding of exosomes in the context of health and disease.
Textician is commercializing a patented breakthrough in machine learning on unstructured text. Called NoNLP(tm) technology, it outperforms both Natural Language Processing (NLP) and Deep Learning in some common use cases. Initial applications are in healthcare IT, specifically ICD-10 coding as a part of RCM applications, delivered either on-premises or via the cloud. In the latter case, no raw PHI is sent to or processed in the cloud, creating a uniquely secure service.
Gencores provides a platform that reduces the risk of concussion with customizable, smart, shock-absorbing helmet inserts.
Verdox is dedicated to reversing climate change through the development and deployment of advanced technology. The company’s proprietary electro-swing process, developed at MIT, enables carbon dioxide and other acid gases to be captured with up to 80% less energy and 70% less cost than conventional approaches.
Flux Marine specializes in developing electric marine propulsion systems designed to enhance performance while minimizing environmental impact. The company focuses on creating electric boat motors that utilize solid-state components to achieve zero emissions, thereby reducing pollution in marine environments. By prioritizing efficiency and sustainability, Flux Marine's motors not only enhance transport capabilities but also significantly lower noise and air pollution. Additionally, these propulsion systems are virtually maintenance-free, contributing to a reduced carbon footprint and promoting cleaner practices within the marine industry.
Developer of a predictive diagnostic biomarker technology designed to predict patient response to specific chemotherapies. The company's technology specializes in advancing in vitro diagnostics tools and personalized medicine to diagnose and treat cancer and reduce unnecessary suffering, enabling physicians to detect cancerous cells.
C-2 Innovations designs and builds all-weather amphibious robots for monitoring, sampling, and mapping various sea-floor terrains. It specializes in areas including; product development, low volume production, business development consulting, contract R&D, and 3-D Animation. C-2 Innovation was founded in 2007 and is based in Shrewsbury, Massachusetts, USA.
Lumme Inc. is a company that specializes in developing an addiction treatment platform that integrates wearable technology, machine learning, and behavioral psychology. Founded in 2014 and based in Amherst, Massachusetts, the platform is designed to function as a personal therapist, providing timely assistance to users. By utilizing sensors on smartphones and smartwatches, Lumme's technology detects, predicts, and prevents behaviors that negatively impact health, specifically targeting addictions to smoking, alcohol, and unhealthy diets. The company's innovative passive gesture recognition technology alleviates the challenges associated with self-monitoring, making it easier for users to manage their behaviors. Lumme Inc. markets its platform to health insurance companies and corporations, aiming to enhance wellness and support addiction recovery.
Developer of a heat sink optimization platform designed to hybridize computational fluid dynamics. The company develops a compliant vapour chamber technology to eliminate thick thermal interface materials in the form of gap fillers and/or thermal grease in the aforementioned hardware, thereby using analytical, numerical, and experimental methods to consult on complex problems involving momentum, heat and mass transport phenomena.
Students looking to enter the maritime, engineering, emergency management and environmental fields should look into the Massachusetts Maritime Academy in Buzzards Bay, Massachusetts—the second oldest maritime academy in the nation. Unique to the school is its “sea term,” a program conducted in January and February. This program gives aspiring cadets the opportunity to apply their education and training as they sail to ports along the Caribbean Sea. During the approximately 52-day voyage, students will also gain real-world experience in seafaring and ship operations like deck and engine watches, and learn how to properly maintain a vessel. Academics offered at the school include more than five bachelor’s degrees, including Emergency Management, Maritime Engineering, Marine Transportation and more. Two graduate degrees are available in Emergency Management and Facilities Management. The school also offers professional and continuing education courses. In addition to an application, admissions require students to submit official high school transcripts, two letters of recommendation, ACT/SAT test scores and proof of citizenship. Tuition is set lower for Massachusetts residents. Financial aid is determined for students on an individual basis. Students who complete a FAFSA will be considered for financial aid through the form of federal and state grants, loans and institutional scholarships.
Techstyle Materials develops multifunctional construction materials that increase energy efficiency, improve comfort, increase durability, and simplify the construction of buildings. The company was founded in 2018 and is headquartered in Somerville, Massachusetts.
Giner Electrochemical Systems, LLC (GES) is a subsidiary of Giner, Inc., established May 2000, as an arms-length alliance between Giner, Inc. and General Motors Corporation (GM). GES is an independent business, majority-owned, controlled and operated by Giner, Inc. The alliance with GM allows us to help develop commercially-viable fuel cells for the next generation of transportation and stationary power systems. GES is also focused on the development and commercialization of related electrochemical technologies, including electrolyzers, sensors and capacitors for a range of applications.
ePaint Company develops specialty antifouling coatings for the United States Coast Guard, The United States Navy, NOAA, Woods Hole Oceanographic Institute, and the U.S Geological Survey. The ongoing research has resulted in three patents.
MicroContinuum offers precision micro-and nano-imprinting and patterning using patented roll-to-roll and batch manufacturing technologies. It y serves a range of clients, including Fortune 100 corporations, startups, and government labs, helping test and develop new nanostructured surfaces for the electronics, lighting, solar, energy harvesting, and health industries.
Pendar Technologies is a privately held company focused on developing advanced autonomous chemistry systems that integrate innovative hardware with machine learning algorithms. By leveraging expert knowledge of molecular spectroscopy, Pendar's technology combines a Raman platform with machine learning to quantify chemical reactants, products, and intermediates in real-time. This capability enables the discovery and scaling of new chemical processes, facilitates rapid responses to emergencies, and contributes to life-saving applications.
Transaera is focused on creating a new generation of affordable and energy-efficient cooling systems designed to minimize energy consumption while providing effective climate control. Their technology aims to enhance indoor environments crucial for both business operations and personal comfort, benefiting human productivity. By offering environmentally friendly cooling solutions, Transaera addresses the need for systems that have a reduced impact on the global climate and local energy infrastructure. These innovative cooling systems are suitable for both residential and commercial applications, enabling consumers to choose options that use significantly less energy compared to traditional air conditioners.
INroof.solar specializes in innovative solar roofing systems that seamlessly integrate solar technology into the architecture of homes. By combining premium roofing materials with a unique solar thermal collection system, INroof.solar transforms the roof into a solar panel, offering a streamlined and aesthetically pleasing appearance. Their Nor’easter solar metal roof panels are specifically designed for cool weather, featuring a smooth coating that facilitates snow shedding and can even heat the roof to melt ice when necessary. In addition to solar hot water and space heating, these panels support radiant floor heating and swimming pool heating, making them a versatile choice for various energy needs. Furthermore, INroof panels are compatible with geothermal heating systems, positioning them as a leading solution for homeowners seeking the benefits of solar energy without the conventional look of traditional solar panels.
Onvector develops non-chemical water treatment technologies that utilize plasma, advanced oxidation, and disinfection process (AOP) that is more robust than ozone or UV. Its Plasma Vortex technology is a plasma hydrocyclone harnessing the power of arc lightning in a controlled cyclone to destroy the most hard-to-treat contaminants in water and wastewater such as PFAS forever chemicals and other contaminants of emerging concern.
Exact Lux builds LED lighting systems using our patent-pending Light Maintenance technology. It eliminates the typical light depreciation of LEDs.
Dynamo Micropower Corporation specializes in developing fuel-flexible gas turbines designed for small distributed generation applications in the oil and gas industry. The company's notable products include PowerCore, which provides continuous power for oilfield operations, and Infernocore, a flameless turboheater. Dynamo's innovative turbine-based solutions offer grid-like power quality while significantly reducing energy costs, with the capability to operate on local unrefined gas, achieving savings of up to 80%. The company also delivers custom power solutions tailored to the specific needs of its clients, facilitating plug-and-play installation on flare gas. Dynamo has established a network of distributors and service partners to support its offerings. Founded in 2011 and based in Somerville, Massachusetts, Dynamo has successfully deployed multiple turbines for prominent customers in the industry.
Spero Devices, Inc. is a technology company specializing in artificial intelligence and nanotechnology, founded in 2015 and headquartered in Acton, Massachusetts. The company develops and manufactures a CMOS-based co-processor designed to enhance computational efficiency in mobile devices. This hardware accelerator targets edge applications that require real-time processing while adhering to mobile power constraints. Spero Devices focuses on multi-object detection, tracking, and segmentation, transforming edge data into actionable cloud intelligence. By leveraging their innovative hardware and software solutions, the company aims to enable advanced services, including the automated selection of AI training data from edge devices.
Kytopen Corp. is a biotechnology company based in Cambridge, Massachusetts, focused on advancing cell therapy through its innovative Flowfect technology. Established in 2017, Kytopen specializes in non-viral delivery systems for molecules into challenging immune cells that are typically hard to transfect. The company utilizes a combination of microfluidics and automation to streamline the delivery process, making it faster, more efficient, and cost-effective. By employing a unique platform that integrates continuous fluid flow with electric fields, Kytopen enables researchers to produce high-quality engineered cells in a matter of minutes while preserving their health and functionality. This approach supports the discovery of novel biological insights and the development of affordable cell and gene therapies.
Uniqarta manufactures technologies that accommodate small, ultra-thin ICs and their inclusion within common materials such as paper or plastic. The result is a class of Smart Materials that eliminate the need for RFID label add-ons and accelerate the IoT evolution.
Inq-ITS (www.inqits.com) are standards-aligned virtual labs for grades 5-10 science. They improve students' competency at science inquiry practices, and cut teachers' grading time by automatically scoring themselves. They want to help EVERY student learn science inquiry practices and critical thinking, and help empower EVERY educator to exceed new science standards. To be successful in the 21st Century, students need their education to go beyond rote memorization.The virtual science labs we create aim to help students to master the inquiry and critical thinking skills that will help them succeed in the classroom and beyond.
Founded in 2015, based on a technology out of Professor Wang's group at WPI, Battery Resourcers, is committed to changing the dynamics for processing end of life lithium ion batteries. Currently most lithium ion batteries are landfilled. If they are recycled only the metal value from the batteries is recovered. Battery Resourcers proprietary process allows one to directly synthesize new cathode materials from spent lithium ion cells. Battery Resourcers will be able to deliver low cost cathode materials to the lithium ion battery market enabling green technologies and resulting in less landfilled material a more sustainable pathway forward.
Titan Advanced Energy Solutions specializes in developing advanced battery management systems for lithium-ion batteries, leveraging patented ultrasound technology to enhance battery performance. Their flagship product, ionView, delivers over 99% accuracy in state-of-health and state-of-charge assessments, which leads to a minimum 20% increase in charge capacity and a 125% extension of battery life. The systems also offer real-time monitoring, safety controls, and cell-level balancing. Titan's solutions cater to a diverse range of industries, including automotive, energy storage, mobile devices, and battery manufacturing, ultimately supporting the electrification and decarbonization efforts for a sustainable future. Founded in 2016 and located in Somerville, Massachusetts, the company was previously known as Titan Energy Analytics.
Metalmark creates nanostructured materials that destroy submicron scale airborne pollutants and toxins to support healthy indoor air quality. It aims to address the challenges associated with air pollution and climate change. The company's air cleaning technology utilizes catalytic materials to filter the air with nanoscale precision.
It was founded in 2017 and is headquartered in Boston, Massachusetts.
Developer of machine-learning software designed to support businesses in building software infrastructure and creation. The company specializes in developing software and API to collect, enrich and stream data from buildings to their digital products and services, enabling engineers to collect commercial building data, which powers their Building Optimization, Cx, RCx, MBCx, and M&V services.
Developer of thermal electric systems intended to deliver clean and low-cost power. The company's electrification system adds an electric boiler in parallel to the existing boiler system and uses dispatching software to manage fuel switching between the boilers without disruption to the supply of steam, enabling industries to offset higher power costs and more emissions-intensive fuels and switch to clean steam energy.
Watchtower Robotics specializes in developing advanced technology for detecting leaks in water distribution systems. Their innovative robot is designed to identify leaks early and accurately, minimizing the risk of water breaks and infrastructure damage. By operating without disrupting water service, the technology allows clients to implement preventative measures before significant leakage occurs. This proactive approach not only helps in preserving water resources but also reduces the potential for costly repairs and downtime associated with water infrastructure failures.
ZwitterCo provides revolutionary membrane solutions for the treatment of highly-impaired wastewater.
Solchroma Technologies, Inc. specializes in the manufacture of full-color, reflective digital display screens designed for advertising applications. Founded in 2015 and headquartered in Somerville, Massachusetts, the company offers non-LED displays that possess sunlight reflective properties and high-quality color reproduction. These displays are particularly suitable for outdoor advertising and on-premise signage. Solchroma's innovative technology features a proprietary system utilizing electroactive polymer actuators, which function as hydraulic pumps to transfer colored ink from reservoirs to color filter chambers. By selectively absorbing ambient light through layered cyan, magenta, and yellow filters, the displays achieve grayscale effects by varying the visible amounts of ink, creating vibrant and dynamic visual presentations ideal for the smart cities of the future.
Developer of radar and arena systems intended to miniaturize radar-sensing and data collection and analysis systems. The company engages in systems capable of scanning through dust, clouds and darkness with high accuracy and has applications in hydrography, oceanography, topography and engineering, thereby providing users with network-based solid-state radar systems for ground and airborne applications.
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
TelAztec is a manufacturer of surface relief microstructures that manipulate light.
Quantum Diamond Technologies, located in Somerville, Massachusetts, is focused on translating advanced quantum science into practical applications. Founded by a team of prominent quantum scientists from Harvard University, the company specializes in the commercialization of nanoscale devices that leverage the principles of quantum mechanics. These innovations enable new possibilities in various fields, including sensing, metrology, and computing. Additionally, Quantum Diamond Technologies is developing an ultrasensitive biomaterial detection and diagnostics platform, further expanding its impact on technology and healthcare.
Manus Bio Inc. recreates plant processes in microorganisms to produce natural ingredients through fermentation. The company’s microbial platform converts sugar sources into ingredients with applications, such as flavors, fragrances, food ingredients, cosmetics, vitamins, pharmaceuticals, and agricultural chemicals. It merges metabolic engineering, protein engineering, and systems biology technologies to generate microbes that produce various plant-based ingredients. The company has a strategic partnership with BBGI Public Company Limited. Manus Bio Inc. was formerly known as Manus Biosynthesis, Inc. and changed its name to Manus Bio Inc. in June 2018. The company was founded in 2011 and is based in Cambridge, Massachusetts. It has manufacturing facilities in Cambridge, Massachusetts; and Augusta, Georgia.
Littoral Power Systems, established in 2015 by experts in the alternative energy sector, focuses on innovative and sustainable hydropower technologies. The company specializes in providing renewable power solutions deployable in remote, non-grid-connected areas. A key feature of Littoral's approach is the development of prefabricated, modular equipment, which simplifies assembly and maintenance, allowing local installation crews with limited resources to effectively implement hydropower systems. The firm produces equipment made from recycled materials, addressing challenges related to cost, environmental impact, and regulatory complexities in ocean energy. Their designs cater to various applications, from small configurations suitable for tight waterways to large energy farms, enabling clients to efficiently harness energy with minimal environmental footprint.
Vata Verks offers non-invasive hi-res water and natural gas data acquisition solution for buildings.
Radial Analytics focuses on addressing significant data challenges in healthcare through its innovative cloud-based planning system. The company's primary product is a decision support solution designed for hospital case managers and discharge planners, enabling them to identify the most appropriate post-acute care facilities for patients. This system utilizes an evidence-driven approach, taking into account each patient's unique clinical, functional, and behavioral needs. By capturing and processing extensive real-time patient data, Radial Analytics helps hospitals optimize the quality of care while reducing post-acute costs for shared-risk patients. The company is partially supported by the National Science Foundation, which aids in the development of technology aimed at creating positive societal and economic impacts.
Infinite Cooling Inc. is a company focused on water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company employs innovative technology utilizing high-voltage electric fields to capture and recycle water that evaporates from cooling towers. This process significantly reduces water waste and helps mitigate water scarcity. By implementing its systems, Infinite Cooling enables power plants, data centers, and factories to lower their water consumption and treatment costs, promoting sustainability in industrial operations.
Xilectric develops energy and environmental technologies with a focus on Li-ion technology.
Silverside Detectors Inc. is a technology company. They develop nuclear radiation detection technologies to protect cities and citizens from nuclear terrorism. It designs and develops advanced and adaptable radiation detectors. These detectors can be installed in urban and transit infrastructure for nuclear detection. The company develops inexpensive thermal neutron detectors that can be a building block for large-area networked scanning and other future solutions for nuclear threat reduction. Silverside Detectors Inc was founded by Sarah Haig and Andrew Inglis in 2013; and is headquartered in Boston, Massachusetts.
Optodot Corporation develops components based on nanotechnology for energy storage, energy conservation, and energy generation markets. It offers NanoPore, a separator that utilizes a patented coating-based manufacturing process to make nano porous ceramic membranes; NPORE lithium ion battery separators; secure infrared coated films and laminates that are used for covert and forensic security applications in various asset security or product/document authentications; and window films. The company focuses on the development of products for lithium ion battery separator and organic solar cell markets; and optical communications, including optical switches, optical buffers, modulators, and photo detectors using optical chip and component technology to enhance optical transport networks. In addition, it provides intellectual property, product development, and contract services in the areas of coatings, as well as focuses on strategic partnerships and licensing to commercialize products for energy, security, and communications solutions. The company serves start-up companies, Global 50 companies, the Department of Defense, and the Department of Energy. It has a strategic partnership with Madico, Inc. The company was founded in 2000 and is based in Woburn, Massachusetts.
Spero Devices, Inc. is a technology company specializing in artificial intelligence and nanotechnology, founded in 2015 and headquartered in Acton, Massachusetts. The company develops and manufactures a CMOS-based co-processor designed to enhance computational efficiency in mobile devices. This hardware accelerator targets edge applications that require real-time processing while adhering to mobile power constraints. Spero Devices focuses on multi-object detection, tracking, and segmentation, transforming edge data into actionable cloud intelligence. By leveraging their innovative hardware and software solutions, the company aims to enable advanced services, including the automated selection of AI training data from edge devices.
Massachusetts Materials Technologies, founded in 2014 and based in Waltham, Massachusetts, is an MIT spin-off focused on transforming innovative ideas into commercially viable products in materials, mechanics, and manufacturing. The company specializes in nondestructive technologies that measure the strength and toughness of materials, particularly in the oil and gas sector. Its advanced instrumentation allows for the accurate assessment of the mechanical properties of pipelines without disrupting service or requiring pipe cutouts. This capability supports the energy industry in evaluating the integrity of natural gas pipelines, ensuring safety and efficiency in operations.
TACTAI is pioneering the world's first wearable device that enables users to touch and feel virtual objects with life-like realism. The company's patent-pending Dynamic Tactile Wave™ technology creates multi-modal experiences by fully engaging the user's senses and bringing touch, sound, and light together. The company's products help create compelling immersive experiences in Augmented Reality/Virtual Reality applications for gaming, e-commerce, training, film, architecture and education.
Developer of radiofrequency and microwave solutions intended to enhance the performance of mission-critical security, surveillance, and communication systems. The company's products include auto-tuning filters, power electronics cores, ferrite circulators and isolators, ferrite phase shifters, high-power microwave components, and microwave ferrite filters, enabling defense and commercial organizations to design and deploy innovative solutions.
VocaliD's award-winning technology generates high-quality, natural sounding voices within hours rather than months using cutting-edge machine learning techniques, proprietary voice blending algorithms, and a crowdsourced Voicebank.
Poly6 Technologies, Inc. offers digital manufacturing solutions to the biotechnology, aerospace, and electronics industry. The company manufactures its products through 3D printing technology. The company develops several stimuli-responsive materials systems that help hardware, software and materials to get integrated into established production processes. Poly6 Technologies, Inc. was incorporated in 2015 and is based in Boston, Massachusetts. As of September 30, 2019, Poly6 Technologies, Inc. operates as a subsidiary of WP CPP Holdings, LLC.
Heila Technologies is an MIT-born startup dedicated to simplifying the integration and operation of individual Distributed Energy Resources (DERs) and microgrids. It is focused on the commercialization of the Heila IQ Platform, a decentralized optimization system that reduces system complexity and cost. The company was founded in 2017 and is based in Somerville, Massachusetts.
Via Separations, Inc. is a company based in Somerville, Massachusetts, focused on developing membrane-based products for the efficient separation of industrial liquids in complex environments. Incorporated in 2016, the company utilizes advanced materials technology that significantly reduces energy consumption—reportedly using ten times less energy than traditional separation methods. Via Separations specializes in industrial decarbonization through its innovative membrane filtration systems, improving selectivity between nano filtration solutes while enhancing temperature stability, solvent resistance, and oxidizer tolerance. This enables manufacturing facilities to increase productivity while minimizing their energy usage.
Upstream Tech conserving freshwater by powering informed water market transactions.
MTPV Power Corporation is a clean energy company based in Austin, Texas, that specializes in Micron-gap ThermalPhotoVoltaics (MTPV) technology. Founded in 2003, the company originated its technology from research at MIT and Draper Laboratory. MTPV Power develops semiconductor chips designed to convert waste heat from various sources into clean energy, primarily electricity. This innovation enables industrial businesses to harness alternative energy sources, thereby enhancing productivity and reducing operational costs. Through its advancements in semiconductor technology, MTPV Power aims to contribute to more sustainable energy solutions in the industrial sector.
NewGrid is a software firm in the utilities industry, focused on the development and commercialization of topology optimization technologies. NewGrid’s software supports power operations and operations planning decision making including outage scheduling and coordination, seasonal contingency planning, remedial action plan and operating guide (Op. Guide) development, and congestion management. Our team is made of engineers, researchers, software developers and economists with years of experience in power systems and markets analysis and design. NewGrid’s founders are thought-leaders in the applications of topology optimization technology to power system operations. With DOE ARPA-E support, they led the first team to ever produce security-constrained topology re-configurations on large-scale RTO systems automatically, with short calculation times acceptable to system operators.
NewGrid is a software firm in the utilities industry, focused on the development and commercialization of topology optimization technologies. NewGrid’s software supports power operations and operations planning decision making including outage scheduling and coordination, seasonal contingency planning, remedial action plan and operating guide (Op. Guide) development, and congestion management. Our team is made of engineers, researchers, software developers and economists with years of experience in power systems and markets analysis and design. NewGrid’s founders are thought-leaders in the applications of topology optimization technology to power system operations. With DOE ARPA-E support, they led the first team to ever produce security-constrained topology re-configurations on large-scale RTO systems automatically, with short calculation times acceptable to system operators.
Wright Electric, Inc. is building technologies for large commercial airplanes. The company is currently developing their flagship Airplane, the Wright 1, which will be a 186-seat single aisle airliner with an 800 mile range. The company hopes to achieve entry to service for the Wright 1 by 2030 and is working with commercial airlines including easyJet and VivaAerobus. In addition to the newly announced U.S. DOE’s ARPA-E funding, the company is funded by Y Combinator, the Clean Energy Trust and venture funds.
Developer of a predictive diagnostic biomarker technology designed to predict patient response to specific chemotherapies. The company's technology specializes in advancing in vitro diagnostics tools and personalized medicine to diagnose and treat cancer and reduce unnecessary suffering, enabling physicians to detect cancerous cells.
Cambrian Innovation Inc. specializes in wastewater treatment systems that utilize innovative technologies to recover resources from wastewater, enabling cleaner water and energy generation. The company's primary offerings include the EcoVolt Reactor, which employs electrically active microbes, and the EcoVolt Mini, a compact system designed for smaller facilities to manage biological oxygen demand and total suspended solids. Additionally, Cambrian provides the EcoVolt MBR, a membrane bioreactor that integrates membrane filtration for effective contaminant removal, particularly for the food and beverage sector. Founded in 2006 and based in Watertown, Massachusetts, Cambrian Innovation initially received a grant from NASA to explore bioelectricity applications for water management, and has since developed a comprehensive portfolio of solutions that assist industrial, agricultural, and municipal clients in efficiently managing and reusing their resources while significantly reducing treatment costs.
Modular Genetics, Inc., a biotechnology company, designs and develops engineered microorganisms that synthesize chemicals using renewable raw materials (sugar). The company was founded in 2000 and is based in Woburn, Massachusetts.
NewGrid is a software firm in the utilities industry, focused on the development and commercialization of topology optimization technologies. NewGrid’s software supports power operations and operations planning decision making including outage scheduling and coordination, seasonal contingency planning, remedial action plan and operating guide (Op. Guide) development, and congestion management. Our team is made of engineers, researchers, software developers and economists with years of experience in power systems and markets analysis and design. NewGrid’s founders are thought-leaders in the applications of topology optimization technology to power system operations. With DOE ARPA-E support, they led the first team to ever produce security-constrained topology re-configurations on large-scale RTO systems automatically, with short calculation times acceptable to system operators.
SimulConsult is a developer of a diagnostic and care planning platform aimed at reducing diagnostic errors and improving the accuracy of clinical assessments. The company's software provides a unified model that spans multiple medical specialties, allowing clinicians to generate comprehensive differential diagnoses that encompass both common and rare diseases. This tool assists healthcare professionals in identifying relevant clinical findings and appropriate tests, thereby facilitating a more efficient and reliable path to confirmed diagnoses. By enabling quicker and more accurate decision-making, SimulConsult enhances the quality of care provided to patients and aims to eliminate the frustrations associated with prolonged diagnostic processes.
MTPV Power Corporation is a clean energy company based in Austin, Texas, that specializes in Micron-gap ThermalPhotoVoltaics (MTPV) technology. Founded in 2003, the company originated its technology from research at MIT and Draper Laboratory. MTPV Power develops semiconductor chips designed to convert waste heat from various sources into clean energy, primarily electricity. This innovation enables industrial businesses to harness alternative energy sources, thereby enhancing productivity and reducing operational costs. Through its advancements in semiconductor technology, MTPV Power aims to contribute to more sustainable energy solutions in the industrial sector.
Developer of radiofrequency and microwave solutions intended to enhance the performance of mission-critical security, surveillance, and communication systems. The company's products include auto-tuning filters, power electronics cores, ferrite circulators and isolators, ferrite phase shifters, high-power microwave components, and microwave ferrite filters, enabling defense and commercial organizations to design and deploy innovative solutions.
Boston Engineering delivers innovative and timely solutions by utilizing its Total System Responsibility™ (TSR) philosophy to meet demanding market needs. Through interdisciplinary teams, best practice strategies and seamless integration with client processes, Boston Engineering offers a complete solution that is both flexible and focused.
Sandymount is a process technology company that serves leading beverage manufacturers. We focus on safety, quality, and responsiveness in delivering new solutions.
Kuva Systems, known formally as MultiSensor Scientific, Inc., specializes in the development and manufacturing of advanced tools for detecting, visualizing, and quantifying methane leaks in the natural gas supply chain. The company offers a Leak Imaging and Quantification System (LIQS), which integrates infrared detection technology, sophisticated electronics, and an intuitive user interface. This system is designed to identify and assess methane emissions in real time, utilizing proprietary algorithms for accurate location and quantification. Kuva Systems also provides software solutions that generate color images of gas leaks, catering to the leak inspection and gas safety industries. Founded in 2015 and based in Cambridge, Massachusetts, the company is focused on enhancing gas detection and safety through innovative imaging technologies.
Evaptainers, LLC, founded in 2014 and headquartered in Somerville, Massachusetts, specializes in manufacturing mobile refrigeration units that operate without electricity. Originating from a Massachusetts Institute of Technology class focused on improving global living conditions, the company has developed innovative modular refrigeration systems that utilize evaporative cooling technology. This method is less energy-intensive than traditional refrigeration and effectively extends the shelf life of agricultural products, potentially tripling or quadrupling their longevity. The units are designed for use along the agricultural supply chain, allowing farmers in developing countries to preserve perishable goods using only sunlight and water. With a focus on modern materials and improved design, Evaptainers has created durable and user-friendly devices that are patent pending and currently unmatched in the marketplace.
Barrett Technology, LLC, founded in 1990 and based in Newton, Massachusetts, specializes in the design and manufacture of advanced robotic manipulators. The company has pioneered technology that enhances the flexibility of articulated arms and hands, establishing itself as a leader in this field. Barrett Technology's innovative manipulators are recognized for their versatility, catering to a wide range of applications across various industries. The company has achieved notable recognition, including a place in the Guinness Book of World Records for its cutting-edge manipulator technology.
Dynamo Micropower Corporation specializes in developing fuel-flexible gas turbines designed for small distributed generation applications in the oil and gas industry. The company's notable products include PowerCore, which provides continuous power for oilfield operations, and Infernocore, a flameless turboheater. Dynamo's innovative turbine-based solutions offer grid-like power quality while significantly reducing energy costs, with the capability to operate on local unrefined gas, achieving savings of up to 80%. The company also delivers custom power solutions tailored to the specific needs of its clients, facilitating plug-and-play installation on flare gas. Dynamo has established a network of distributors and service partners to support its offerings. Founded in 2011 and based in Somerville, Massachusetts, Dynamo has successfully deployed multiple turbines for prominent customers in the industry.
Erbi Biosystems is a transformative microfluidic bioprocess instrumentation company.
AddiLat is an electronics process technology based company.
With over $150 billion spent on delivered fuels (i.e. Propane, Heating Oil, Diesel, etc.) every year, fuel distribution companies struggle to efficiently plan deliveries with more than 50% of all delivery miles (or about 1/6th of total market spend) being unnecessary. Tank Utility uses real-time tank level measurements from IoT monitors and innovative business intelligence software to eliminate wasted delivery miles while helping fuel providers provide a better customer experience through greater transparency..
With over $150 billion spent on delivered fuels (i.e. Propane, Heating Oil, Diesel, etc.) every year, fuel distribution companies struggle to efficiently plan deliveries with more than 50% of all delivery miles (or about 1/6th of total market spend) being unnecessary. Tank Utility uses real-time tank level measurements from IoT monitors and innovative business intelligence software to eliminate wasted delivery miles while helping fuel providers provide a better customer experience through greater transparency..
HMSolution, Inc., a water technology company, develops water treatment systems that remove arsenic and other toxic contaminants from drinking water. It offers its systems for various drinking water applications, such as community water systems, beverage companies, agricultural companies, and households relying on wells that need a point-of-entry or point-of-use system. The company was founded in 2013 and is based in Providence, Rhode Island.
Energid Technologies provides software, products, and support to solve the most difficult robotics problems. Energid's robotics software simulates and controls kinematics and dynamics for all types of robotics applications, and their 3D machine vision software supports autonomy. Whether your challenge is in the field of medicine, agriculture, space-based systems, defense, or manufacturing, together they can solve it.
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
Primaira provides product development, engineering research, and specialized testing to amplify innovation in the appliance, consumer products, health & safety, and military industries.
Founded in 2007 by leading MIT roboticists, Hstar Technologies Corporation pursues groundbreaking robotics research and development with the support of private investors and more than $7 million in grants from the U.S. Small Business Innovation Research (SBIR) program. Hstar develops industry-leading robots to enhance automation quality in warehouse, healthcare and research settings, making improvements in the areas of automation intelligence, safety, flexibility and human productivity. Hstar's team is comprised of innovative, highly trained robotics engineers with more than thirty years of collective robotics development experience, including work with the MIT Computer Science and Artificial Intelligence (CSAIL) Laboratory, development of telerobotic surgery and artificial limb / biomimetic robot technology, and autonomous robotic systems.
EverVest specializes in financial risk analysis and cash flow modeling software tailored for renewable energy investors. The company's web-based platform enables banks, investors, and developers to effectively analyze and structure financing for new renewable energy projects. Additionally, it offers enterprise risk management features that assist portfolio managers in making informed decisions, thereby promoting sustainable growth within the renewable energy sector.
Artaic, LLC, established in 2007 and based in Boston, Massachusetts, specializes in designing and fabricating custom tile work for both commercial and residential markets. The company offers a wide range of mosaic and tile designs suitable for various applications including bathrooms, backsplashes, flooring, hotels, kitchens, lobbies, outdoor spaces, pools, and restaurants. In addition to its design services, Artaic provides installation services to clients. The company employs advanced technology, utilizing computer-aided design software, a cloud-based logistics system, and an innovative robotic mosaic assembly system to ensure precision and efficiency in its projects. Artaic has garnered support through investments from angel investors and corporate offices, as well as significant non-dilutive grant funding from various organizations.