MassChallenge

HeroSupport is a medical device manufacturing company based in Veyrier, Geneva, established in 2019. The company specializes in creating personalized solutions that transform imaging and treatment tables into medical immobilization devices designed to enhance patient comfort during clinical procedures. By providing tailored support, these devices allow patients to receive prone breast radiotherapy without the need to adapt to the standard table setup. This innovation not only improves patient comfort but also aims to enhance the effectiveness and cost efficiency of cancer treatment for healthcare providers.

Aseptuva is an early-stage MedTech startup located in Technopark Winterthur, dedicated to addressing Healthcare-Associated Infections (HAI) that arise from catheter use in healthcare facilities. Catheters, essential for delivering medications, are often contaminated with pathogens, leading to severe complications such as pneumonia and bloodstream infections, which result in significant mortality and substantial healthcare costs. To combat this issue, Aseptuva is developing innovative medical devices designed for in-situ disinfection of various catheters, aiming to prevent infections before they occur. The company’s technology offers a robust automated system that assists medical staff, ultimately helping hospitals reduce the incidence of infections and save lives. Aseptuva aspires to establish a new standard in critical care, positively influencing millions of patients worldwide.

CNS Therapy, they contribute to human well-being through mind-body therapy and the research, design, education, and sale of devices that alleviate chronic disease, restore health, and extend useful life. They are a spin off from the University of North Carolina (UNC). Their base technology is a patent pending approach to chronic pain which combines operant behavioral therapy with a proprietary device which enhances learning and resets the autonomic nervous system - called SET - Systolic Extinction Training. They are dedicated to providing long lasting pain relief to patients. Their unique combination of psychological training and electrostimulation helps chronic pain patients to starkly reduce or even eliminate their pain and allow them to return to their daily lives.

Clean Valley CIC is a group of entrepreneurs, engineers, and environmental scientists with nature-inspired ideas for Canadian Innovation. Clean Valley provides nature-based solutions for the aquaculture industry and medical technology.

True Concepts Medical Technologies is a medical device company dedicated to reducing financial waste in the healthcare system while enhancing patient outcomes. Founded in 2017 and based in Centerville, Ohio, the company develops innovative, cost-effective technologies that aim to save billions of dollars annually. Its flagship products are designed to improve the accuracy of medical procedures, including contaminant-free blood culture collection for sepsis diagnosis and treatment solutions for sudden cardiac arrest. By leveraging clinical experience and the product development expertise of Pixel and Timber, True Concepts Medical Technologies creates devices that minimize human error, ensure consistent clinical delivery, and ultimately reduce healthcare costs.

KT Innovations is a provider of medical devices that aims to prevent costly & life threatening urinary tract and skin infections.

MZP Tech is a company focused on point-of-care coagulation analysis, aiming to improve healthcare delivery through innovative diagnostic methodologies. They develop medical devices capable of rapidly analyzing blood samples, utilizing a disposable micro-machined chip and a portable embedded sensing system. This technology allows for the analysis of a single drop of blood within minutes, measuring blood viscosity. By doing so, MZP Tech enables healthcare professionals to conduct early-stage screenings for various conditions, including cardiovascular diseases, blood-clotting disorders, and hyperviscosity-related issues. Their advancements in hemostasis contribute to better management of bleeding and thrombotic risks, enhancing patient care.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

Bairitone Health, founded in 2022 and headquartered in Houston, Texas, develops innovative solutions for individuals with untreated obstructive sleep apnea. The company specializes in remote passive sensing technology that employs vibration sensors placed on the face during sleep to gather acoustic data from the upper airway. This data is then analyzed using sonar beam-forming algorithms and artificial intelligence, allowing for precise identification of sound locations associated with structural collapses in the upper airway during apnea episodes. By providing detailed insights, Bairitone Health enables healthcare professionals to formulate informed treatment plans for sleep apnea, addressing a critical health issue for many individuals.

Ember Sleep is a company focused on improving sleep quality through its innovative sleep apnea treatment platform. The platform features medical devices designed to be more comfortable, effective, and non-invasive for the treatment of sleep apnea. By providing a novel approach to open the airway, Ember Sleep aims to enhance the well-being of patients, enabling them to feel more rested while assisting healthcare professionals in delivering better health outcomes.

Taurus Vascular is a medical device company dedicated to enhancing long-term outcomes for patients with aortic aneurysms. The company is focused on developing innovative technology aimed at transforming the standard of care for these patients. Its novel medical device is designed to eliminate the adverse effects of endoleaks and promote accelerated shrinkage of aneurysm sacs following endovascular aortic aneurysm repair (EVAR). By addressing these critical issues, Taurus Vascular aims to improve patient outcomes within the healthcare industry.

Lighthouse Tech specializes in designing smart eyewear frames aimed at individuals with vision impairment, blindness, and spatial perceptual disorders. Their innovative product detects obstacles above the waist and alerts users through soft haptic vibrations. The eyewear is crafted to resemble conventional frames or sunglasses, ensuring that users do not compromise on style while benefiting from enhanced safety and mobility. By combining functionality with fashion, Lighthouse Tech promotes independent outdoor navigation, ultimately fostering a greater sense of self-sufficiency and well-being for its customers.

Corveus Medical is focused on creating innovative solutions to prevent heart failure through the development of a neuromodulation device. This catheter-based technology aims to safely and effectively access nerve tissue, enabling nerve ablation for improved treatment outcomes. By employing minimally invasive methods, Corveus Medical seeks to alleviate both the clinical and economic burdens associated with heart failure, marking a significant advancement in the field of cardiac care. The company is committed to delivering consistent results and enhancing patient quality of life through its pioneering approach to heart failure treatment.

Women aged 20-45 cannot get screened for breast cancer because existing solutions are unreliable. However, 81% want to. At The Blue Box, we have built a pain-free, low-cost, sensitive, radiation-free device to detect breast cancer in urine with a sensitivity of 83%. In 2024, we’ll launch into the market, bringing The Blue Box to private gynecology clinics with a Diagnostics-as-a-Service subscription model, and a pay-per-test revenue stream that we’ll share with doctors.

Curespec is focused on developing a medical device known as Nephrospec, aimed at addressing the interconnected challenges of chronic kidney disease and hypertension. The device is designed to preserve kidney function, thereby delaying the need for dialysis and treating high blood pressure. By providing healthcare professionals with an innovative tool, Curespec seeks to reduce the suffering associated with kidney failure and hypertension, ultimately improving patient outcomes in these prevalent health conditions.

IC Innovations develops disruptive technology for respiration measurement and analysis. We are focused on lowering the barriers to access to advanced respiratory assessment, in fields such as sports and healthcare.

Astron Medtech is a medical technology company focused on improving patient outcomes in tendon repair. The company develops disposable minimally invasive surgical devices that significantly reduce recovery time from six months to four months. By utilizing less invasive and sustainable surgical techniques, Astron Medtech aims to enhance the efficiency of surgical services while providing better options for patients undergoing tendon repair procedures.

HME Square is a digital healthcare company focused on developing medical diagnostics and devices that utilize innovative technology for health monitoring. The firm specializes in creating non-invasive glucose monitoring systems designed to measure health data accurately and continuously without the need for blood sampling or needles. By integrating photoacoustics, MEMS device technology, and deep learning into a cohesive digital data platform, HME Square aims to prevent chronic diseases and empower individuals to manage their glucose levels effectively, thereby promoting healthier lifestyles.

XN Health is a medical device company based in Texas, founded in 2021. The company specializes in developing healthcare devices aimed at improving the process of mechanical ventilation. Its innovative technology focuses on phrenic nerve stimulation, which induces diaphragm contractions during ventilation. This approach helps protect against diaphragm dysfunction in patients who are mechanically ventilated, ultimately enabling them to wean off the ventilator more quickly and safely.

ABBY is a new Personal EV for adults with reduced mobility, positioned as a long-overdue expansion play for the broken $9B wheelchair cartel

DoubleLock Healthcare specializes in developing innovative medical devices aimed at reducing healthcare-associated infections. Their primary product is a novel intravenous (IV) port and syringe system designed to enhance sterility and safety. This system, which does not require alcohol swabs or caps, is engineered to decrease healthcare costs, minimize medication errors, and improve overall patient safety in hospitals and other medical facilities.

ZiO Health is a biotechnology company that focuses on transforming laboratory testing through its proprietary pocket-sized technology, which allows for point-of-care diagnostics. By combining advanced biosensor technology with machine learning algorithms, ZiO Health provides real-time testing results tailored to each patient's unique profile. This innovative approach enables users to measure, test, and detect the molecular composition of various substances, facilitating personalized health insights. The company's devices aim to optimize health management and enhance patient outcomes, allowing individuals to conduct quality home diagnostics and take proactive steps in preventing illness.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Blue Halo BioMedical, LLC, founded in 2019 and based in Winter Park, Florida, specializes in developing innovative catheter surgical devices tailored for urologic patients. The company aims to transform the longstanding urologic catheter market with its fully internal male urinary catheter designed to effectively drain the bladder. This proprietary device addresses a key issue in urologic care by reducing the risk of catheter-associated urinary tract infections (CAUTI) and significantly improving the quality of life for patients. By allowing individuals to void at will, Blue Halo BioMedical’s catheters enable users to engage in normal activities without the limitations imposed by traditional catheter systems.

Intek Scientific develops multiplexed immunofluorescence imaging technology.This will empower clinicians and researchers to gain a deeper understanding of cancer and provide effective and customized therapeutic strategies to tackle even the most challenging cancers.

Electronrx specializes in personalized digital medicine, focusing on innovative solutions for chronic disease management and hospital patient care. The company has developed a predictive healthcare and diagnostics platform that monitors cardiovascular health remotely. This platform utilizes advanced technologies, including biomedical engineering, data science, and machine learning, to sense the physiological environment and deliver tailored therapeutic interventions. By enabling clinical professionals to provide targeted treatments through short waveforms of current and voltage, Electronrx empowers patients to self-monitor their health and effectively manage conditions such as period pain during treatment.

Unsmudgeable offers anti-smudge eyeglasses lens coating that is safe, productive, and convenient in a single application.

Code 1 Medical Devices provides medical solutions to prevent the aspiration of stomach contents into the lungs.

SensArs is a medical equipment manufacturing company specializing in neuromodulation technology aimed at treating diabetic neuropathy. The company has developed an innovative implantable neurostimulator electrode designed to restore sensory feedback by delivering precise electrical impulses to the nerve fibers that transmit pain signals. This technology not only assists healthcare providers in enhancing patient functionality but also offers a long-term solution for pain management. SensArs' flagship system, SENSY, is particularly beneficial for patients with amputations or nerve damage, as it helps to restore natural sensations in their feet.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

N95 Mask Preserve is a PPE protection device developed for healthcare workers on the COVID-19 frontlines. It is built with antimicrobial, antifungal, mold, and mildew inhibiting technology. It protects masks from damage and contamination.

SafetySit is a company focused on creating assistive therapeutic devices aimed at supporting disabled or recovering patients who struggle to maintain an upright sitting position due to insufficient core muscle strength. The company has developed a mobile backrest designed to aid clinicians in treating these patients, facilitating the early mobilization process essential for recovery. This innovative product reduces the need for clinicians to provide manual support, thereby enhancing the efficiency of therapy sessions and improving overall patient outcomes. By prioritizing user comfort and clinical effectiveness, SafetySit aims to advance rehabilitation practices and support the recovery journey for individuals with mobility challenges.

Astellar Labs specializes in developing non-invasive diagnostic technology for measuring blood glucose levels without the need for finger pricks or frequent device replacements. Their technology, powered by artificial intelligence, tracks blood glucose over time, predicts trends, and provides early warnings to patients, enhancing comfort and cost-effectiveness.

WestFace Medical is a medical device company focused on enhancing vascular access procedures through innovative imaging technology. Their flagship product, SingleStick™, features a patented imaging adapter that employs optical coherence tomography (OCT) to provide real-time visualization of needle trajectories during vascular access. The system consists of a disposable handheld imaging adapter that attaches to any hollow bore needle and an OCT image processor, which displays the captured images. This technology allows clinicians to visualize anatomical markers in real-time, thereby improving clinical outcomes and patient satisfaction while potentially reducing costs associated with vascular access procedures. By offering a solution that facilitates traditional techniques with advanced imaging capabilities, WestFace Medical aims to redefine the standard of care in this critical area of healthcare.

Vaccine Systems develops automated equipment designed to streamline the vaccine preparation process for healthcare workers, enhancing access to immunization for patients, particularly in developing countries. By addressing inefficiencies in current vaccine handling, the company's technology reduces vaccine waste, which can range from 30% to 70%, and mitigates issues related to short expiration times and manual preparation. This innovation not only simplifies vaccine mixing but also provides an essential margin of safety for vaccines prepared at the point of care, ultimately saving significant labor time and increasing vaccination rates during global campaigns.

Advanced Microfluidics, based in Ecublens, Switzerland, is a machinery manufacturing company that specializes in developing and producing high-end lab equipment components. Their primary focus is on automated liquid handling systems, which are designed to minimize cross-contamination and reduce internal volume, ensuring precise and efficient fluidic performance. The company's products cater to both laboratory and industrial sectors, providing solutions with no dead volumes.

NemoCare is developing the smartest and most comprehensive patient monitoring and management system. It is an innovative, continuous vital sign data acquisition, analysis and prediction engine that combines unobtrusive wireless wearable sensors and networks, analytical algorithms and big data to provide affordable continuous, high resolution monitoring for all newborns in hospital, and at home. We use design thinking principles to build life-saving technologies that will transform the way healthcare is delivered. Our current area of work is in newborn and maternal care.

INIA Biosciences focuses on creating non-invasive medical devices that leverage sound wave technology to manage chronic inflammatory diseases. The company's innovative system combines biomarker monitoring with an ultrasound stimulator, aimed at reducing inflammation associated with transplant rejection and decreasing reliance on immunosuppressant medications. This home-administered, closed-loop monitoring system provides physicians with advanced diagnostic capabilities to improve the treatment and prevention of organ failure, ultimately enhancing patient care in chronic disease management.

Thermy is a healthcare company focused on addressing the challenge of late-stage breast cancer diagnoses in Mexico, Latin America, and the Caribbean. The company has developed an AI-powered infrared imaging device that offers a comfortable and radiation-free alternative to traditional mammograms, facilitating early detection of breast cancer. This non-invasive method operates on both mobile and desktop platforms, allowing healthcare professionals to utilize infrared cameras to assess the likelihood of breast cancer in patients. By improving access to early detection, particularly in underserved communities, Thermy aims to enhance survival rates and reduce mortality associated with late diagnoses of breast cancer.

MoviWear is a technology company that specializes in medical AI and remote monitoring solutions, primarily through its platform MoviWearMED. This platform is designed to monitor patients' vital signs in real-time, whether they are at home, in retirement facilities, or on the go. By utilizing proprietary 5G IoT NurtureWatch wearables, MoviWear can detect critical changes in health indicators such as heart rate, temperature, blood pressure, and oxygen levels, as well as alerting caregivers in case of falls. The company addresses the increasing demand for continuous health monitoring outside of traditional hospital settings, particularly for seniors. Founded in 2017, MoviWear aims to enhance patient safety and prevent health emergencies, drawing inspiration from a personal family experience. Its clientele includes health and telecommunications companies across North America, Europe, and Israel.

GiveMove is a healthcare technology company specializing in the manufacture of assistive mobility devices for individuals with motor disabilities. Their flagship product, Bipmov, is a comprehensive suite of static and motorized standers for both adults and children, incorporating IoT technology. The company aims to provide innovative, practical, and customized solutions to enhance the well-being of users and their surroundings, working closely with healthcare practitioners to achieve this goal.

Through the experience of 15-year skin optics research, we developed optical modules that work in conjunction with sophisicated algorithms to quantify various skin contents such as hemoglobin, bilirubin, skin collagen, skin oxidative stress, blood glucose variation, and etc. In contrast to the market available wearable optical modules that can only measure heart beat rate, our wearable module design provides much more information for personal health monitoring and thus could have multitude application scenarios with great marketing potential.

Insu Health Design, founded in 2018 in San Juan, Puerto Rico by Mason Lucich and Doris Candelaria, specializes in creating a personal-use system for the safe storage of medications. Their innovative storage solution combines a thermoelectric cooler, vacuum flask, and fluid loop to maintain optimal temperatures for medicines, particularly bio-medicines like insulin. The product is equipped with affordable solar panels and a portable, battery-powered cooler featuring multiple charging options. This design allows patients to safeguard their health by ensuring that their medications remain viable during travel, power outages, or emergency situations.

LucyDx is dedicated to preventing blindness in diabetics through early detection of retinal eye disease. The company offers a wearable, compact, and non-invasive diagnostic device that utilizes electroretinogram (ERG) technology to identify diabetic retinopathy at an early stage. This innovative system empowers diabetics to monitor their eye health proactively and assists medical professionals in tracking and managing eye damage before it becomes irreversible. By focusing on early detection and treatment, LucyDx aims to help individuals preserve their eyesight and improve their overall quality of life.

Manus Robotics is focused on developing a smart health and wellness device aimed at promoting independent and healthy living. The company offers a wearable robot that assists individuals with disabilities in their daily activities, providing intelligent support to enhance their quality of life. In addition to daily living assistance, the device collects and analyzes muscle data from patients, facilitating rehabilitation efforts and helping users regain independence.

Augmental Technologies, Inc., established in 2019 and headquartered in Boston, Massachusetts, specializes in developing innovative, hands-free technologies that integrate with the human body. The company's core focus is creating augmented reality and assistive technology solutions, targeting both situational and severe motor impairments. By exploring the mouth as an untapped interface for human-computer interaction, Augmental aims to enhance information access and increase autonomy, particularly for individuals living with upper extremity paralysis.

Adventus Robotics specializes in the development and production of self-driving power wheelchairs. Utilizing artificial intelligence and autonomous technology, their products are designed to safely and accurately navigate various environments, enhancing mobility for individuals with severe physical disabilities and reducing motion sickness. Adventus offers a solution that can be mounted onto existing manually-operated powered wheelchairs, ensuring accessibility for a wide range of users.

NeuroGeneces utilizes advanced neuroscience, sleep expertise, and artificial intelligence to deliver brain health assessments aimed at enhancing cognitive longevity. The company has received funding from various reputable sources, including government agencies and private investors. Its flagship product is a sleep headband equipped with machine learning algorithms that analyze EEG data, comparing it against a proprietary normative database to determine an individual's biological brain age. This innovative approach allows healthcare practitioners to objectively evaluate brain function and develop targeted intervention strategies. Additionally, the device monitors sleep patterns, including quantity, quality, and heart rate variability, providing essential support for clinicians focused on wellness and preventative care. By identifying neurodegeneration early, NeuroGeneces aims to empower users to optimize their mental and physical performance.

FormaPath develops innovative laboratory tools aimed at enhancing tissue sample preparation for diagnostic purposes. The company has created an automated adipose tissue separation instrument designed to improve laboratory automation and patient care by effectively isolating lymph nodes from surrounding fat, resulting in higher yields. Additionally, FormaPath is collaborating with a prominent medical center to develop a specimen preparation system that automates the grossing process in anatomic pathology labs, thereby facilitating the detection of cancer spread. By equipping pathologists with advanced technology, FormaPath aims to provide accurate information that supports timely and reliable diagnoses for patients.

Vironix Health specializes in developing advanced machine-learned surveillance technologies that enable real-time, remote monitoring and detection of health deterioration related to respiratory illnesses such as COVID-19, influenza, and chronic obstructive pulmonary disease (COPD). The company's innovative platform offers a range of services, including remote patient monitoring, therapeutic monitoring, and chronic care management, equipping healthcare providers with the necessary tools to deliver effective care from a distance. Vironix Health's proprietary APIs are designed to be hardware agnostic, allowing integration into various applications utilized by patients, healthcare providers, and employers for enhanced institutional wellness. Founded by a team of dedicated scientists, physicians, technologists, and entrepreneurs, the company was established in response to the global impact of the COVID-19 pandemic, aiming to improve patient outcomes while reducing healthcare costs.

Neurava is a company focused on developing non-invasive wearable diagnostic devices for patients with epilepsy, particularly those at risk of Sudden Unexpected Death in Epilepsy (SUDEP). The company's innovative device monitors critical biological signals related to epilepsy, providing timely alerts to caregivers and patients. By offering a reliable monitoring solution, Neurava aims to enhance patient autonomy and deliver peace of mind to families, facilitating timely intervention when necessary. The company's work lies at the intersection of medical device manufacturing and health diagnostics, addressing a significant need within the epilepsy patient community.

Yengii Biosciences develops the Galet smartphone microscope for detecting infectious illnesses such as malaria, sleeping sickness, and tuberculosis. The Galet platform is intended to do very complicated blood film analysis in a simple, portable point-of-care tool, which is now limited to high-end laboratories. Making such blood film analysis more available would allow for the early diagnosis of the most serious health concerns, such as malaria, and will save lives.

Munevo GmbH, founded in 2011 and based in Nuremberg, Germany, specializes in developing innovative technology to enhance mobility for individuals with disabilities. The company is known for its flagship product, munevo DRIVE, a Smartglass application that enables users to control electric wheelchairs through head movements, translating these movements into digital signals for hands-free operation. This technology provides users with greater independence and the ability to navigate both indoor and outdoor environments. In addition to the Smartglass application, Munevo also offers various adaptors and accessories to complement its solutions, further supporting the mobility needs of its users.

Diamante is an Italian company founded in 2016 and headquartered in Verona, specializing in the development and manufacture of diagnostic devices for autoimmune diseases using advanced nanomaterials. The company utilizes plants as bioreactors to produce nanoparticles derived from modified plant viruses. This innovative approach facilitates the creation of new diagnostic tools and therapies aimed at addressing autoimmune diseases, particularly through techniques that involve the re-induction of these conditions. By leveraging plant-based nanotechnologies, Diamante is positioned to contribute significantly to advancements in autoimmune disease diagnosis and treatment.

Gelatex is a materials technology company based in Estonia, founded in 2016 and incorporated in the UK in 2019. The company has developed a patented technology for producing bio-based nanofibers efficiently and cost-effectively, making it possible to produce these materials at a scale that is significantly faster and cheaper than traditional methods. Gelatex's production process utilizes gelatin derived from low-value waste in the meat and leather industries, ensuring that its products are made from natural and non-toxic substances, which promotes sustainability in the textile sector. Initially focused on creating eco-friendly leather-like textiles, the company pivoted during the COVID-19 pandemic to explore a broader range of applications for its nanofibers, including 3D scaffolds for tissue engineering, cultured meat, bio-based filters, energy storage, and wound care.

BestHealth4U focuses on the research and development of advanced solutions for manufacturers of class 1 medical devices. The company specializes in medical adhesive technologies that aim to prevent skin injuries, accelerate healing, and enhance overall patient health. Its innovative and environmentally friendly adhesive products are designed to safeguard patients from skin damage, discomfort, irritation, and infections by improving the attachment of bandages, dressings, and medical devices to the skin. By providing effective solutions, BestHealth4U assists healthcare providers in reducing medical adhesive-related skin injuries and promoting the well-being of patients.

Advanced Interactive Response Systems - AIRS in Newaygo, Michigan, provides oxygen supply monitoring systems for hospitals, homes, and other remote areas. With this system, the patient is able to safely monitor air flow for oxygen tanks. It has an alarm feature that sends updates via text messaging or Bluetooth™. The AIRS devices are also wirelessly linked to each other using a secure and robust mesh networking protocol. Hospitals and medical personnel will greatly benefit from this state-of-the-art monitoring system.

Diagnoly is a medical device company focused on enhancing fetal examination through the use of artificial intelligence. The company has developed an AI-powered plug-in device that allows clinicians to perform ultrasound imaging of human fetuses in real-time. This innovative technology analyzes key fetal biometric parameters, assisting healthcare professionals in identifying complex fetal pathologies and potential pregnancy complications. By streamlining the ultrasound examination process, Diagnoly aims to improve the accuracy and efficiency of fetal health assessments.

Aidplex is a MedTech startup focused on transforming the orthopedics sector through innovative, patient-centered products. With operations in both the United States and Greece, the company addresses the stagnation in orthopedic product development, which has largely remained unchanged for decades. Aidplex specializes in wearable devices that enable real-time monitoring of patients' health and treatment progress, specifically targeting scoliosis and fracture management. By integrating biometric sensors into their designs, Aidplex provides physicians with critical information necessary to track patient improvements continuously. The company's mission is to enhance the effectiveness and comfort of orthopedic care, ultimately revolutionizing how patients are monitored and treated.

Criam is a biotechnology company based in Braga, Portugal, founded in 2015. It specializes in the research and development of a medical device designed for blood type analysis and the detection of infectious diseases. The company's flagship product offers rapid and accurate testing for various conditions, including HIV, Brucella, tick fever, syphilis, mononucleosis, and meningitis. This portable device operates independently of electricity or laboratory infrastructure, making it accessible for use in diverse environments. Additionally, Criam's technology is scalable, allowing a single reader to perform multiple tests using specific cartridges and advanced computer vision algorithms. By optimizing blood testing services, Criam aims to provide timely health information and improve clinical decision-making.

Kobara Medical is focused on addressing the heart failure market, specifically targeting Heart Failure with Preserved Ejection Fraction (HFpEF), a condition impacting over three million individuals and on the rise. The company has developed a minimally invasive therapeutic device that utilizes neuromodulation therapies to improve cardiac function without the need for invasive procedures. By employing the heart's transverse pericardial sinus, the device allows for multi-chamber pacing and combines multiple leads into a single, elegant solution, thus avoiding the complications associated with penetrating blood vessels. Kobara Medical aims to enhance treatment options for patients suffering from heart failure and cardiac arrhythmias by leveraging innovative approaches to heart anatomy.

Paragit Solutions specializes in the development of innovative systems for remote patient monitoring and data-driven management of movement disorders, particularly Parkinson's disease. Their flagship product, the Paragit Sleeve, utilizes a patented sEMG (electromyography) technology to capture sensitive data on muscle activation, movement, and grip force during patients' daily activities. Paragit offers two software solutions: the PD Monitor, designed for caregivers to manage Parkinson's disease through data interpretation of key motor symptoms such as rigidity and tremor, and the MD Lab, tailored for decentralized clinical trials across various movement disorders. The PD Monitor provides caregivers with visual data to enhance treatment optimization and telemedicine practices, while the MD Lab enables researchers to analyze over 20 metrics related to disease severity, facilitating comparisons and tracking trends across different patient groups. This integration of hardware and software allows for improved patient care and more efficient clinical research.

Epios personalized and precision management of brain disorders using daily life monitoring and therapeutics. The Epios system comprises a series of thin leads incorporating sensing electrodes and a miniature implant, inserted beneath the skin. The neural signals are wirelessly transmitted to an external receiver held in place on the skin directly over the implant with a magnet, and from there are conveyed to a wearable data processor and are finally securely stored in the Epios Cloud.

Babylat is a developer of an innovative automated medical device designed for the protein enrichment of human milk. This small-scale tabletop device allows for on-site protein extraction in hospitals without the need for expensive laboratory equipment. By concentrating the protein fraction from human milk efficiently and quickly, Babylat's technology ensures that newborn babies receive an adequate supply of protein, which is crucial for their growth and development. The device represents a significant advancement in neonatal care, making essential nutritional support more accessible in various healthcare settings.

4Blind is a technology company focused on developing innovative engineering solutions for the blind and deaf-blind communities. The company conducts research and creates products aimed at enhancing communication, education, employment, transportation, and independent living for individuals with visual disabilities. By addressing the unique challenges faced by these communities, 4Blind seeks to expand opportunities and eliminate barriers, enabling deaf-blind individuals to communicate effectively and allowing blind individuals to engage with tactile images. Through its dedicated efforts, 4Blind strives to improve the overall quality of life for people with disabilities.

Munevo GmbH, founded in 2011 and based in Nuremberg, Germany, specializes in developing innovative technology to enhance mobility for individuals with disabilities. The company is known for its flagship product, munevo DRIVE, a Smartglass application that enables users to control electric wheelchairs through head movements, translating these movements into digital signals for hands-free operation. This technology provides users with greater independence and the ability to navigate both indoor and outdoor environments. In addition to the Smartglass application, Munevo also offers various adaptors and accessories to complement its solutions, further supporting the mobility needs of its users.

Serenno Medical is a medical device company based in Yokneam Illit, Israel, founded in 2017. The company specializes in developing a urine output measuring device designed for use in intensive care units (ICUs). Its flagship product, the Sentinel device, provides accurate, automatic, and continuous monitoring of urine output, enabling healthcare providers to detect and assess the risk of acute kidney injury (AKI) in hospitalized patients. This technology enhances patient safety while reducing the workload for medical staff and lowering costs associated with patient care. By offering real-time data on kidney function, Serenno Medical aims to improve fluid management and facilitate early intervention, ultimately helping to prevent severe kidney damage and reduce hospital stays.

Pacify Medical Technologies is a medical device startup focused on developing innovative wound care treatments. The company has created a patented device that sprays skin tissue onto wounds, promoting faster healing and recovery. This advanced technology aims to address clinical needs in burn care and other injury treatments, enabling hospitals to enhance their patient care capabilities. By commercializing this next-generation medical device, Pacify Medical seeks to improve the effectiveness of wound healing and provide a novel approach to managing injuries.

SlitLED Israel is a 3D & digital, mobile eye-examination system operating remotely and in real-time.

V-Opt is an eye-care telemedicine company, integrating the key examination devices from the ophthalmologist clinic into a single, autonomous unit to be widely deployed in the retail & pharmacy chains. Leveraging advanced AI and ML algorithms, screening & follow-up visits will be replaced with <7min self-test, including fundus, lens, IOP, and much more, and shared with by the person’s own ophthalmologist. V-Opt will truly enable transforming ophthalmology modality from treatment to prevention.

IMMA Health specializes in remote fertility monitoring, empowering women to manage their fertility journey at home. The company's core product is an automated, AI-driven intravaginal ultrasound device, coupled with a dedicated mobile app. This system allows women to perform self-administered transvaginal scans in the comfort and privacy of their homes, reducing the need for frequent clinic visits and associated stress. IMMA's innovative approach aims to create a comprehensive, dedicated, and innovative environment for fertility care.

Travaxy LTD operates an online travel booking platform focused on serving individuals with disabilities and senior travelers. Founded in 2016 and headquartered in Ramat Yishai, Israel, the company enables users to plan and book accessible holidays by providing options for hotels, flights, car rentals, and medical solutions. The platform is designed to identify travelers who may need additional assistance during the booking process and offers tailored services and information about accessible attractions, concerts, and venues at their chosen destinations. Travaxy aims to enhance the travel experience for those with mobility challenges and ensure they have access to the necessary resources for a comfortable journey.

Liposphere develops and manufactures AqueousTech, an innovative water-based platform technology that offers advanced lubricants for various medical and technological applications. This IP-protected technology creates a durable protective boundary layer on both biological and synthetic surfaces, effectively resisting high loads and pressures. AqueousTech is significantly more effective than traditional oil- and hyaluronic-based substances, and it is biocompatible. The company's flagship product, AqueousJoint, is designed as a local injectable treatment for knee osteoarthritis. Additionally, Liposphere's technology utilizes hydration water as the key lubricating element, allowing for efficient coating of surfaces and enabling the encapsulation and targeted delivery of active pharmaceutical ingredients or supplements.

VenoVision is an AI-driven platform that specializes in contactless cardiopulmonary monitoring, aiming to enhance cardiac care for patients with heart failure and those at risk. By utilizing a thermal imaging monitoring device, VenoVision provides continuous hemodynamic assessments, allowing medical teams to gain insights that were previously only available through invasive cardiac catheterizations. The system is designed to monitor patients post-hospitalization, identifying and alerting healthcare providers to any deterioration in conditions before they escalate, thereby reducing costly admissions to cardiac ICUs. This innovative approach not only improves patient stability at discharge but also facilitates compliance monitoring for various conditions, ultimately contributing to better outcomes for millions of patients.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, that focuses on innovating respiratory health management through advanced biosensors and artificial intelligence. Founded in 2016, Strados Labs develops a wearable device that provides real-time insights into respiratory metrics such as breathing speed, sounds, and patterns. This device is equipped with a continuous breathing sensor that enables remote monitoring of patients with respiratory conditions like asthma and chronic obstructive pulmonary disease. By connecting the device to a mobile application, patients and healthcare providers can access critical respiratory data, facilitating informed decision-making and improved management of respiratory health.

4Blind is a technology company focused on developing innovative engineering solutions for the blind and deaf-blind communities. The company conducts research and creates products aimed at enhancing communication, education, employment, transportation, and independent living for individuals with visual disabilities. By addressing the unique challenges faced by these communities, 4Blind seeks to expand opportunities and eliminate barriers, enabling deaf-blind individuals to communicate effectively and allowing blind individuals to engage with tactile images. Through its dedicated efforts, 4Blind strives to improve the overall quality of life for people with disabilities.

MindMics is an innovative wearable technology company focused on health monitoring through sound-based platforms integrated into earbuds and hearing aids. By capturing clinically meaningful biometrics in real-time, such as circadian rhythms, breathing rates, body temperature, and heartbeats, MindMics aims to enhance mental performance and overall well-being. The technology allows users to gain insights into their health, facilitating improved focus, satisfaction, and mindfulness. Through this approach, MindMics seeks to provide users with tailored products and experiences that promote mental peace and enhance daily living.

Mosaic health data provides medical records of complete data of a patient's health across the continuum of care

Zibrio is a balance diagnostics company based in Houston, Texas, that was established in 2017. The company specializes in a technology that utilizes insights from postural control and machine learning to detect subtle changes in balance. Originally developed from NASA technology designed for astronauts returning from space, Zibrio's device aims to empower individuals to take charge of their health. By measuring balance and weight, it helps users understand their balance profiles and offers guidance for improvement. The company's mission is to enhance health outcomes, reduce the risk of falls, and promote overall balance and well-being.

Kinto.Care is an online platform designed to enhance communication and support for caregivers, particularly those caring for loved ones with dementia. The platform offers user-generated content and digital tools that facilitate care team collaboration, medication management, and tracking of health data. By providing practical advice, care planning, and group learning opportunities, Kinto.Care aims to empower family members to effectively coordinate care and manage their loved ones' medical needs through a unified interface.

Haptic (WearWorks), a B2B SaaS company creating a universal language through touch. We have patented the haptic navigation technology, which made history. Haptic guided the first runner who is blind in the NYC Marathon with their HapticNav app. Haptic is redefining inclusive mobility. Our patented technology uses tactile communication to guide users through subtle vibrations, offering a seamless, screen-free, ears-free experience. This empowers all users—especially those with visual impairments—to navigate independently. Haptic is revolutionizing inclusive technology. Our patented HapticNav tool transforms how we navigate the world, offering a hands-free, eyes-free experience through the power of touch. It empowers thousands, especially those with visual impairments, to reclaim their independence and live screen-free.

Limula is a company that has developed an innovative platform technology designed to enhance the scalability of cell therapy production. By integrating a bioreactor and a centrifuge into a single device, Limula's solution enables healthcare providers to manufacture cell and gene therapies in a decentralized manner, bringing these treatments closer to patients. This platform, which includes hardware, software, and consumables, aims to make highly personalized and curative therapies more accessible. The automation of the production process not only increases safety and reproducibility but also allows for the large-scale manufacturing of cell therapy products, thereby addressing the critical need for improved access to gene-engineered therapies.

Code 1 Medical Devices provides medical solutions to prevent the aspiration of stomach contents into the lungs.

PREEMIEr Diagnostics is a healthcare provider focused on the health of premature infants, specifically aimed at preventing retinopathy of prematurity. The company has developed a diagnostic device that measures blood glucose levels in these vulnerable patients. This technology assists healthcare professionals in identifying premature infants who require adjustments to their glucose levels, facilitating early detection of potential health issues. By improving the management of glucose levels, PREEMIEr Diagnostics contributes to enhancing the overall health outcomes for premature infants.

Starling Medical focuses on creating a remote patient monitoring platform that facilitates at-home urine diagnostics, integrating seamlessly into everyday bathroom routines. The company is developing a healthcare device that employs mass spectroscopy-based sensors to continuously monitor changes in urine composition. This technology aims to enable early detection of chronic health issues, allowing both patients and healthcare providers to intervene promptly and potentially prevent serious complications or hospitalizations. By offering predictive insights, Starling Medical aspires to enhance health outcomes through proactive monitoring.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

Readily3D is a Swiss company based in Lausanne, specializing in volumetric 3D printing solutions. Founded in 2020 as a spin-off from the École Polytechnique Fédérale de Lausanne (EPFL), the company has developed innovative printers capable of producing complex, patient-specific devices in under 30 seconds using tomography. Their technology utilizes a liquid photosensitive polymer, which is cured through dynamic light patterns from multiple angles, allowing for the creation of tailored orthoses for patients with hearing loss and surgical models for medical professionals. This approach not only enhances patient care but also streamlines surgical planning, positioning Readily3D as a leader in the advancement of personalized medical devices.

Healium is a mental fitness tool that offers a drugless approach to managing anxiety, sleep, addiction, and burnout. The company utilizes patented technology that connects to biometric data from consumer wearables, such as smartwatches and EEG headbands, allowing users to monitor their brainwaves and heart rate. This information is used to create a reactive, immersive media experience that adapts to the user's bio-data. Healium's unique platform has been validated by eight peer-reviewed studies, demonstrating its effectiveness in reducing anxiety and improving mood within minutes. By leveraging existing sensors and devices, Healium provides a controlled virtual and augmented reality environment for users seeking to enhance their mental well-being.

TomoWave is a company focused on developing innovative imaging technologies for clinical medicine and preclinical research. Utilizing its proprietary optoacoustic and laser ultrasonic imaging modalities, TomoWave aims to enhance cancer detection, guide medical interventions, and monitor the effectiveness of cancer therapies. The company's technology, which captures images by "listening to the sound of light," allows for highly detailed visualization of tissues, particularly in relation to vascular and blood-related conditions. Founded by Dr. Alexander Oraevsky, a pioneer in biomedical optoacoustics, TomoWave has a strong emphasis on generating intellectual property and advancing it from concept to validated clinical prototypes. The company is committed to bringing its technologies to market through appropriate regulatory certifications, thus contributing to improved diagnostic capabilities in healthcare.

Soma Devices offers a Train-of-Four (TOF) quantitative device that measures the level of neuromuscular blockade in patients during surgery. A novel approach to measure TOF requires the capture of limited movement of the thumb when the hands are strapped in suboptimal locations. The device includes a full glove, versatile to accommodate many hand sizes, and is easy to put on. Our vision is that anesthesiologists will be using the TOF device as part of routine checking to avoid postoperative issues.

Articulate Labs, Inc. is a medical device company based in Austin, Texas, that specializes in developing wearable technology for the treatment of knee osteoarthritis. Founded in 2009, the company produces KneeStim, a device that employs neuromuscular electrical stimulation (NMES) to enhance muscle function and support rehabilitation during everyday activities. By integrating motion-tracking hardware and clinician input, the device tailors stimulation patterns to align with the user's natural movement, effectively combating muscle atrophy and inhibition associated with chronic conditions or recovery from surgery. Articulate Labs aims to make physical rehabilitation more accessible and effective, allowing patients to engage in their daily routines while receiving therapeutic benefits.

GaitIQ’s™ mission is to create an affordable, accessible, and easy-to-use application for Alzheimer’s screening in primary care. Our machine vision and artificial intelligence-based software measure subtle changes in gait (how a person walks) correlated with future dementia. Early detection and intervention provide hope to prevent or slow the progression of the disease to debilitating symptoms we recognize as dementia. Today fewer than 50% with dementia ever get a diagnosis.

Tremedics develops bioresorbable technology for congenital heart disease patients with congenital heart disease need devices that resorb within their bodies as they grow. Their technology utilises a minimally invasive surgery procedure for stent delivery and permits vessel growth as the stent resorbs in the body.

Equine Smartbit, LLC is a company based in Saint Louis, Missouri, that specializes in the design and manufacture of a health monitoring device for horses called SmartBit. Established in 2016, the company creates technology that allows horse owners, trainers, and veterinarians to monitor and analyze the wellness, health, and performance of horses in real-time. The SmartBit device utilizes biometric sensors to capture vital signs, including temperature, heart rate, and blood oxygen saturation, by assessing data through a non-invasive system. This technology not only matches performance metrics with a horse's biometrics but also sends alerts when the horse's physical condition is suboptimal. Additionally, Equine Smartbit provides software tools to further assist in understanding the health and training of horses, thus enhancing their overall care and performance.

HiPR Innovation, founded in 2019 and based in Laredo, Texas, specializes in pressure management solutions for wheelchair users, aiming to prevent pressure ulcers. The company has developed a pressure management system that delivers real-time data to wheelchair patients, caregivers, and healthcare professionals. This innovative system features a reactive air pressure cushion, designed to adapt to individual needs by using an intrinsic algorithm to alleviate pressure in areas prone to ulcers. By providing reliable pressure visualization and management strategies, HiPR Innovation enhances the quality of care for individuals at risk of developing pressure ulcers, thereby improving their overall well-being.

ChondroNest is focused on developing medical technologies aimed at cartilage reconstruction, specifically targeting conditions such as Osteochondritis and Osteoarthrosis. The company is creating a device made from modified biopolymers intended for in vivo use, facilitating easier and more effective reconstruction surgeries for surgeons. ChondroNest plans to conduct preclinical tests on animal models before moving on to human trials. Following these initial trials, the company intends to license its product to major MedTech companies for sales and marketing purposes, while maintaining control over the production of its ChondroNest™ pastes.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

EarlySight SA is a Swiss company, established in 2016 and based in Lausanne, that focuses on developing innovative medical devices for the early detection and treatment of eye diseases. The company has created an advanced eye fundus camera that enhances retinal imaging through precise illumination and real-time correction of ocular aberrations. This device utilizes cellular-level imaging technology to identify subtle structural changes in the retina, allowing for effective monitoring of treatment outcomes in a quick and non-invasive manner. By facilitating the visualization of cell morphology within the retina, EarlySight aims to improve the capabilities of eye specialists in diagnosing and managing ocular conditions.

Solenic Medical, Inc. is a medical device company founded in 2019 and based in College Station, Texas. It specializes in developing a non-invasive treatment for infected metallic implants using a technology that employs alternating magnetic fields generated by external coils. This innovative approach targets biofilm on the surfaces of medical implants, which is a significant complication in surgeries like knee and hip replacements, as well as in trauma-related procedures involving plates and rods. The technology has the potential to replace the costly and risky two-step revision surgical procedure currently used to address chronic infections in medical implants, thereby offering a safer and more effective solution for patients.

NeuroRescue Inc. develops and manufactures medical devices that facilitate therapeutic hypothermia for patients experiencing stroke, cardiac arrest, and head injuries. Its flagship product, NeuroRescue SC3, enables emergency medical technicians to non-invasively initiate therapeutic temperature management in the field using off-the-shelf cold packs. This device allows for a seamless transition to controlled and monitored continuous cooling when the patient arrives at the hospital. By improving the standard of care, NeuroRescue’s technology aims to enhance neurological outcomes by up to forty percent, addressing the limitations of current treatment protocols that can lead to longer recovery times. Founded in 2010 and headquartered in Lafayette, Louisiana, NeuroRescue is focused on transforming emergency medical practices to improve patient recovery.