Mereo Biopharma

Mereo Biopharma, established in London in 2015, specializes in acquiring and advancing late-stage drug candidates from larger pharmaceutical companies. These candidates, often overlooked due to resource constraints, target rare and specialized diseases with significant unmet medical needs. Mereo's strategy involves rapidly progressing these assets through clinical development, either by partnering or divesting them, or directly commercializing them, particularly in orphan disease indications. The company combines operational efficiency with financial resources, leveraging a unique partnership with a leading global CRO, ICON, to conduct comprehensive clinical studies. Mereo's focus is on transforming the lives of patients worldwide by developing innovative medicines that can significantly improve their quality of life.

John Richard

Head of Corporate Development and Co-Founder

1 past transactions

OncoMed Pharmaceuticals

Acquisition in 2018
OncoMed Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Redwood City, California, focused on discovering and developing innovative therapeutics targeting the biological mechanisms underlying cancer growth, resistance, recurrence, and metastasis. The company is advancing several therapeutic candidates, including Navicixizumab, a bispecific monoclonal antibody designed to target Delta-like ligand 4 and vascular endothelial growth factor, which has undergone clinical trials for advanced solid tumors, metastatic colorectal cancer, and platinum-resistant ovarian cancer. Additionally, OncoMed is developing Etigilimab, an anti-TIGIT monoclonal antibody that is currently in clinical trials for advanced or metastatic solid tumors. The company aims to provide new treatment alternatives by leveraging its understanding of cancer stem cells, which are critical to tumor initiation. OncoMed has established strategic alliances with leading pharmaceutical companies, including Celgene Corporation and Bayer Pharma AG, to facilitate the discovery and development of novel therapeutics. Founded in 2004, OncoMed Pharmaceuticals operates as a subsidiary of Mereo BioPharma Group plc.
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