Morgenthaler Ventures, founded in 1968 and based in Portola Valley, California, is a seasoned venture capital firm with over 45 years of experience in investing across various market cycles. The firm focuses on a diverse range of sectors, including business-to-business (B2B), business-to-consumer (B2C), healthcare, information technology, software as a service (SaaS), manufacturing, and life sciences. Morgenthaler Ventures has built a notable portfolio that includes companies such as Evernote, Lending Club, and Siri, reflecting its commitment to supporting innovative businesses. As a Registered Investment Adviser, the firm emphasizes strategic partnerships with industry-leading management teams to foster growth and create long-term shareholder value.
Moximed, Inc. is a medical technology company based in Hayward, California, focused on developing innovative solutions for patients with knee osteoarthritis. The company offers the Atlas System, an implantable joint unloader designed to alleviate pain for individuals suffering from medial compartment knee osteoarthritis. This system operates similarly to a shock absorber, providing dynamic load reduction to minimize joint pain and enhance mobility. Moximed also features the MISHA Knee System, which offers an outpatient treatment option for patients who have not found relief through other therapies and are not suitable candidates for knee replacement surgery. By addressing the specific needs of osteoarthritis patients, Moximed aims to improve their quality of life while potentially delaying the need for more invasive surgical interventions. Founded in 2006, the company serves patients and medical professionals worldwide.
LA-CO Industries is a chemical company that specializes in the manufacture of a diverse range of products, primarily focused on plumbing chemicals and industrial marking tools. The company produces markers for various applications, including livestock identification and industrial uses, as well as temperature indicators and welding supplies. In addition to these products, LA-CO Industries offers a variety of chemical products, inks, paints, and sterilization inks. Their extensive portfolio serves multiple sectors, emphasizing quality control and fabrication materials. Through its commitment to innovation and quality, LA-CO Industries supports a wide array of industries with essential chemical and marking solutions.
Webster Industries is a manufacturer specializing in engineered class chains, sprockets, and vibratory equipment for material handling and power transmission applications. The company designs and produces tailored products to meet client needs, emphasizing product excellence and continuous improvement in its manufacturing processes. By focusing on innovation and customer satisfaction, Webster Industries aims to deliver value through its specialized offerings in the engineered class chain and related equipment markets.
Family owned distributors of detail products and auto body supplies. They also conduct coating certificate courses. They provides all types of car detailing, polishing and painting.
Precision Pipeline, LLC, a pipeline contracting company, provides pipeline construction services for the gas and oil industry in the United States. The company focuses on liquid and gas pipeline construction. It offers services in the areas of transmission, gathering, maintenance, integrity testing, hydrostatic testing, and horizontal directional drilling.
Flexpipe is a manufacturer specializing in steel modular systems for lean manufacturing. The company produces a range of products, including coated steel pipes, joints, roller tracks, panels, fasteners, casters, and various related tools and accessories. By providing these components, Flexpipe aims to enhance productivity for its clients in commercial and industrial sectors.
Relievant Medsystems, Inc. is a medical device company focused on developing minimally invasive treatments for chronic axial low back pain. The company has created the Intracept procedure, which specifically targets the basivertebral nerve to alleviate chronic vertebrogenic low back pain. By delivering targeted energy into the spine, the Intracept System effectively blocks the transmission of pain signals, providing patients with a low-risk therapeutic option. Founded in 2004, Relievant is headquartered in Minneapolis, Minnesota, with additional operations in Sunnyvale, California.
SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.
Moximed, Inc. is a medical technology company based in Hayward, California, focused on developing innovative solutions for patients with knee osteoarthritis. The company offers the Atlas System, an implantable joint unloader designed to alleviate pain for individuals suffering from medial compartment knee osteoarthritis. This system operates similarly to a shock absorber, providing dynamic load reduction to minimize joint pain and enhance mobility. Moximed also features the MISHA Knee System, which offers an outpatient treatment option for patients who have not found relief through other therapies and are not suitable candidates for knee replacement surgery. By addressing the specific needs of osteoarthritis patients, Moximed aims to improve their quality of life while potentially delaying the need for more invasive surgical interventions. Founded in 2006, the company serves patients and medical professionals worldwide.
Terraflos is a biotechnology company that focuses on creating innovative and sustainable health solutions by combining natural substances with advanced technology. The company specializes in a diverse range of products, including supplements and food items, which are designed to promote wellness and vitality. Utilizing methods such as cellular agriculture and precision fermentation, Terraflos maximizes the potential of plant-based resources to develop premium offerings that enhance human well-being. Additionally, the company's commitment to sustainability ensures that its practices have a positive impact on the climate while respecting nature and the environment. Through its integrated approach, Terraflos aims to provide effective health tools that merge the power of nature with scientific advancements.
80/20 is a leading manufacturer of modular aluminum T-slotted building systems designed for a variety of industrial applications. The company specializes in providing T-slot aluminum profiles, which feature channels that enable the connection of various components, such as panels and bearings. This versatile building system allows users to create customized solutions tailored to specific needs. 80/20 focuses on addressing automation challenges and offers scalable solutions for machine frames, robotic support, displays, and evolving requirements. Its products cater to both industrial and end-market customers, ensuring flexibility and adaptability in design and functionality.
SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.
Ideal Aluminum specializes in designing and manufacturing premium aluminum fences, gates, railings, and related outdoor products for both residential and commercial applications. The company offers a diverse range of products, including cantilever, estate, and ornamental gates, as well as railings and louvers. Ideal Aluminum focuses on delivering durable and low-maintenance solutions, catering to clients who prioritize quality and longevity in their outdoor installations.
Waterfront Brands Waterfront Brands offers a complete line-up of premium brands across its divisions. Waterfront manufactures and distribute to dealers and distributors around North America,
DecoArt is a manufacturer specializing in paints and finishes tailored for consumers, decorative painters, and crafters. The company offers a diverse range of acrylic colors designed for arts, crafts, and home decorating applications. Its product lineup includes items such as lamp paints, color wheel paint sets, and a variety of acrylics in multiple hues. DecoArt aims to provide durable and high-quality products at affordable prices, catering to the needs of creative individuals. Additionally, the company offers free shipping on orders of $50 or more, enhancing accessibility for its customers.
Relievant Medsystems, Inc. is a medical device company focused on developing minimally invasive treatments for chronic axial low back pain. The company has created the Intracept procedure, which specifically targets the basivertebral nerve to alleviate chronic vertebrogenic low back pain. By delivering targeted energy into the spine, the Intracept System effectively blocks the transmission of pain signals, providing patients with a low-risk therapeutic option. Founded in 2004, Relievant is headquartered in Minneapolis, Minnesota, with additional operations in Sunnyvale, California.
SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.
Garmat USA specializes in the manufacturing of paint booths and finishing solutions tailored for various industries, including collision repair, aerospace, automotive, marine, and industrial applications. The company offers a diverse range of products, such as downdraft paint booths, modified paint booths, closed-top open-front booths, waterborne booths, and mixing stations. These solutions are designed to improve productivity and reduce operating costs for clients, making Garmat USA a key player in the spray paint booth and refinish equipment market.
Garmat USA specializes in the manufacturing of paint booths and finishing solutions tailored for various industries, including collision repair, aerospace, automotive, marine, and industrial applications. The company offers a diverse range of products, such as downdraft paint booths, modified paint booths, closed-top open-front booths, waterborne booths, and mixing stations. These solutions are designed to improve productivity and reduce operating costs for clients, making Garmat USA a key player in the spray paint booth and refinish equipment market.
Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases. Nuvaira is currently working on a novel catheter-based system that has the potential to improve lung function, exercise capacity, and quality of life for patients with chronic obstructive pulmonary disease. It was founded in 2008 and headquartered in Minneapolis, Minnesota.
NuoDB, Inc. specializes in developing a cloud-based relational database solution tailored for global applications. Its platform utilizes a memory-centric architecture that optimizes storage and replication, ensuring ACID consistency and transactional integrity across distributed databases located in multiple data centers worldwide. NuoDB's features include on-demand scalability, redundancy, policy-driven automation, and support for flexible schemas, making it suitable for various applications such as cloud migration, elastic scalability, and hybrid workloads. The database solution can be deployed on-premises, in containers, or across public, private, and hybrid clouds. NuoDB primarily serves industries such as mobile telecommunications, financial services, and interactive entertainment, along with application providers and independent software vendors. Founded in 2008 and headquartered in Cambridge, Massachusetts, NuoDB also has offices in Dublin, London, and Sofia. It operates as a subsidiary of Dassault Systèmes SE.
Vapotherm, Inc. is a medical technology company based in Exeter, New Hampshire, specializing in the development and commercialization of proprietary Hi-VNI technology products designed to treat patients experiencing respiratory distress. The company offers a range of Precision Flow systems, including Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic, and Precision Flow Heliox, which deliver heated, humidified, and oxygenated air at high velocities through a small-bore nasal interface. In addition to these systems, Vapotherm provides various companion products, such as the Vapotherm Transfer Unit for patient mobility, the Q50 compressor for air supply, and aerosol delivery accessories. The company aims to enhance clinical outcomes while improving patient comfort and compliance, and it primarily sells its products to hospitals through a direct sales organization in the United States and select international distributors. Founded in 1993, Vapotherm continues to focus on innovative solutions that enhance the quality of life for patients of all ages.
Olympic Ophthalmics is a medical device company based in Issaquah, Washington, focused on developing innovative treatments for dry eye disease (DED). Founded in 2017 by Michael Gertner, the company specializes in creating devices that stimulate the trigeminal parasympathetic pathway, thereby activating the glands responsible for tear film production. This approach enables healthcare professionals to effectively address the signs and symptoms of chronic dry eye in patients, contributing to improved ocular health.
SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.
Safe Fuel Systems is a certified repair facility recognized by both the FAA and EASA, specializing in the testing, repair, overhaul, and modification of fuel systems, hydraulics, and associated accessories. The company caters to a diverse clientele, including major domestic and international aircraft operators as well as military aviation. Safe Fuel Systems is committed to providing round-the-clock support, ensuring that clients receive timely and efficient repair services. By employing lean management techniques and optimized shop floor practices, the company aims to deliver high-quality repair solutions at reduced costs, meeting the operational needs of its customers effectively.
Big Switch Networks Inc. specializes in data center networking technologies aimed at enhancing operational efficiency and agility for organizations worldwide. Founded in 2010 and headquartered in Santa Clara, California, the company offers a range of solutions including the Big Monitoring Fabric, which serves as a network packet broker for security chaining and visibility, and the Big Cloud Fabric, a software-defined networking solution compatible with various cloud environments such as VMware and OpenStack. These products facilitate improved networking capabilities in on-premises, public, and multi-cloud settings. Big Switch Networks has established partnerships with industry leaders like Dell EMC and HPE, and actively contributes to open-source networking communities. The company also has operations in Japan and maintains a presence in over 25 countries, reinforcing its commitment to providing innovative networking solutions.
DreamLine is a manufacturer and distributor based in Warminster, Pennsylvania, specializing in bathroom fixtures and accessories. The company offers a range of products, including shower doors, tub doors, shower enclosures, and acrylic shower bases, allowing customers to customize their shower fittings according to their preferences. Known for its sleek modern designs and impressive value, DreamLine has gained recognition for both its off-the-shelf and custom shower door solutions, effectively serving the bath and shower marketplace.
Vapotherm, Inc. is a medical technology company based in Exeter, New Hampshire, specializing in the development and commercialization of proprietary Hi-VNI technology products designed to treat patients experiencing respiratory distress. The company offers a range of Precision Flow systems, including Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic, and Precision Flow Heliox, which deliver heated, humidified, and oxygenated air at high velocities through a small-bore nasal interface. In addition to these systems, Vapotherm provides various companion products, such as the Vapotherm Transfer Unit for patient mobility, the Q50 compressor for air supply, and aerosol delivery accessories. The company aims to enhance clinical outcomes while improving patient comfort and compliance, and it primarily sells its products to hospitals through a direct sales organization in the United States and select international distributors. Founded in 1993, Vapotherm continues to focus on innovative solutions that enhance the quality of life for patients of all ages.
Moximed, Inc. is a medical technology company based in Hayward, California, focused on developing innovative solutions for patients with knee osteoarthritis. The company offers the Atlas System, an implantable joint unloader designed to alleviate pain for individuals suffering from medial compartment knee osteoarthritis. This system operates similarly to a shock absorber, providing dynamic load reduction to minimize joint pain and enhance mobility. Moximed also features the MISHA Knee System, which offers an outpatient treatment option for patients who have not found relief through other therapies and are not suitable candidates for knee replacement surgery. By addressing the specific needs of osteoarthritis patients, Moximed aims to improve their quality of life while potentially delaying the need for more invasive surgical interventions. Founded in 2006, the company serves patients and medical professionals worldwide.
Relievant Medsystems, Inc. is a medical device company focused on developing minimally invasive treatments for chronic axial low back pain. The company has created the Intracept procedure, which specifically targets the basivertebral nerve to alleviate chronic vertebrogenic low back pain. By delivering targeted energy into the spine, the Intracept System effectively blocks the transmission of pain signals, providing patients with a low-risk therapeutic option. Founded in 2004, Relievant is headquartered in Minneapolis, Minnesota, with additional operations in Sunnyvale, California.
Miramar Labs is a company based in Sunnyvale, California, that specializes in developing medical devices for aesthetic purposes, particularly focusing on the treatment of primary axillary hyperhidrosis in adults. Founded in 2006, the company offers the miraDry System, which provides a non-invasive solution for excessive sweating and odor. This system employs microwave energy to selectively target and permanently eliminate sweat and odor glands in the underarm area. By addressing these concerns, Miramar Labs aims to enhance the confidence and quality of life for individuals suffering from this condition. However, the miraDry System is not designed to treat hyperhidrosis in other areas of the body, such as the hands and feet.
NuoDB, Inc. specializes in developing a cloud-based relational database solution tailored for global applications. Its platform utilizes a memory-centric architecture that optimizes storage and replication, ensuring ACID consistency and transactional integrity across distributed databases located in multiple data centers worldwide. NuoDB's features include on-demand scalability, redundancy, policy-driven automation, and support for flexible schemas, making it suitable for various applications such as cloud migration, elastic scalability, and hybrid workloads. The database solution can be deployed on-premises, in containers, or across public, private, and hybrid clouds. NuoDB primarily serves industries such as mobile telecommunications, financial services, and interactive entertainment, along with application providers and independent software vendors. Founded in 2008 and headquartered in Cambridge, Massachusetts, NuoDB also has offices in Dublin, London, and Sofia. It operates as a subsidiary of Dassault Systèmes SE.
Big Switch Networks Inc. specializes in data center networking technologies aimed at enhancing operational efficiency and agility for organizations worldwide. Founded in 2010 and headquartered in Santa Clara, California, the company offers a range of solutions including the Big Monitoring Fabric, which serves as a network packet broker for security chaining and visibility, and the Big Cloud Fabric, a software-defined networking solution compatible with various cloud environments such as VMware and OpenStack. These products facilitate improved networking capabilities in on-premises, public, and multi-cloud settings. Big Switch Networks has established partnerships with industry leaders like Dell EMC and HPE, and actively contributes to open-source networking communities. The company also has operations in Japan and maintains a presence in over 25 countries, reinforcing its commitment to providing innovative networking solutions.
Vapotherm, Inc. is a medical technology company based in Exeter, New Hampshire, specializing in the development and commercialization of proprietary Hi-VNI technology products designed to treat patients experiencing respiratory distress. The company offers a range of Precision Flow systems, including Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic, and Precision Flow Heliox, which deliver heated, humidified, and oxygenated air at high velocities through a small-bore nasal interface. In addition to these systems, Vapotherm provides various companion products, such as the Vapotherm Transfer Unit for patient mobility, the Q50 compressor for air supply, and aerosol delivery accessories. The company aims to enhance clinical outcomes while improving patient comfort and compliance, and it primarily sells its products to hospitals through a direct sales organization in the United States and select international distributors. Founded in 1993, Vapotherm continues to focus on innovative solutions that enhance the quality of life for patients of all ages.
Elcelyx Therapeutics, founded in 2010 and headquartered in San Diego, California, focuses on developing innovative treatments for diabetes and obesity-related metabolic disorders through its proprietary Gut Sensory Modulation (GSM) technology. The company's lead product candidate, NewMet, is designed to improve glucose metabolism by amplifying hormone release in the lower gut, thereby addressing significant unmet needs in the oral anti-diabetic market. Currently entering Phase 2b development, NewMet represents a potential breakthrough in diabetes management. Elcelyx also offers Lovidia, which targets similar metabolic issues without causing systemic side effects. The company is supported by a skilled management team, experienced investors, and a network of scientists and clinicians. In 2013, Elcelyx established NaZura BioHealth Inc. to focus on developing additional non-NewMet assets, further expanding its research and product pipeline.
Adara is a company that provides an online audience targeting platform to help brands enhance their competitive edge in the digital marketplace. By utilizing proprietary data and audience segmentation, Adara offers actionable insights that guide business planning and improve consumer engagement. The platform enables travel brands and advertisers to gain a comprehensive understanding of their audience by analyzing real customer data. This allows advertisers to tailor their offerings and effectively reach specific audiences based on their buying habits, ultimately facilitating more personalized marketing strategies.
SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.
Kona Medical, Inc. is a medical technology company founded in 2009 and based in Issaquah, Washington. It specializes in the development of a non-invasive ultrasound-based therapy system aimed at treating hypertension, particularly in patients with drug-resistant hypertension. The company's flagship product, Surround Sound, utilizes ultrasound imaging to precisely guide the application of focused ultrasound energy for renal denervation, targeting the nerves connected to the kidneys to help regulate blood pressure. By offering a less invasive alternative to traditional treatments, Kona Medical seeks to address the health risks associated with high blood pressure while improving patient outcomes through advanced therapeutic techniques.
Principia Biopharma is a private, pre-clinical stage company initially focused on the discovery and development of differentiated small molecule drugs targeting inflammatory/autoimmune diseases as well as cancer. The company expects to submit an IND for its lead program in 2013 and continues to invest in additional programs and its reversible covalent platform.
Ra Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company headquartered in Cambridge, Massachusetts, focused on developing therapeutics for diseases associated with the overactivation of the complement system. Utilizing a peptide chemistry platform, the company creates synthetic macrocyclic peptides that combine the specificity of antibodies with the pharmacological advantages of small molecules. Its lead candidate, Zilucoplan, is an injectable treatment that has completed Phase II clinical trials for generalized myasthenia gravis and paroxysmal nocturnal hemoglobinuria, along with a Phase Ib trial for patients with renal impairment. Additionally, Ra Pharmaceuticals is advancing pre-clinical programs targeting Factor D inhibition for C3 glomerulonephritis and other complement factors for various diseases. The company has established a collaboration with Merck & Co., Inc. to explore orally available cyclic peptides for non-complement cardiovascular targets. Founded in 2008, Ra Pharmaceuticals operates as a subsidiary of UCB SA.
Vapotherm, Inc. is a medical technology company based in Exeter, New Hampshire, specializing in the development and commercialization of proprietary Hi-VNI technology products designed to treat patients experiencing respiratory distress. The company offers a range of Precision Flow systems, including Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic, and Precision Flow Heliox, which deliver heated, humidified, and oxygenated air at high velocities through a small-bore nasal interface. In addition to these systems, Vapotherm provides various companion products, such as the Vapotherm Transfer Unit for patient mobility, the Q50 compressor for air supply, and aerosol delivery accessories. The company aims to enhance clinical outcomes while improving patient comfort and compliance, and it primarily sells its products to hospitals through a direct sales organization in the United States and select international distributors. Founded in 1993, Vapotherm continues to focus on innovative solutions that enhance the quality of life for patients of all ages.
Galleon Pharmaceuticals, Inc. is a pharmaceutical company based in Horsham, Pennsylvania, founded in 2003. It specializes in discovering and developing treatments for sleep apnea and related breathing control disorders. The company has a portfolio of therapeutics, including GAL-021, a small molecule administered intravenously to support respiratory drive in surgical and critical care patients, and GLN-21,160, an oral candidate aimed at treating sleep apnea. Additionally, Galleon is developing GAL-044, a small molecule designed to prevent surgical pain. The company's focus extends to addressing conditions such as ventilator weaning, anesthetic-induced respiratory depression, chronic obstructive pulmonary disease (COPD), and obesity-hypoventilation syndrome, with the goal of improving respiratory health for patients.
MuleSoft, Inc. is a provider of the Anypoint Platform, a cloud-based application integration solution that enables organizations to connect their applications, data, and devices. Founded in 2006 and headquartered in San Francisco, California, MuleSoft's platform facilitates the creation of application networks by leveraging APIs, which serve as the essential connection points for data exchange among various systems. This integration software suite allows businesses to connect both cloud-based and on-premises applications, regardless of format or source, promoting operational agility and competitive advantage. MuleSoft's offerings include self-serve infrastructure through reusable building blocks, empowering customers to efficiently compose applications tailored to their needs. The company operates as a subsidiary of Salesforce and maintains a strategic alliance with IQVIA to enhance its service offerings.
Moximed, Inc. is a medical technology company based in Hayward, California, focused on developing innovative solutions for patients with knee osteoarthritis. The company offers the Atlas System, an implantable joint unloader designed to alleviate pain for individuals suffering from medial compartment knee osteoarthritis. This system operates similarly to a shock absorber, providing dynamic load reduction to minimize joint pain and enhance mobility. Moximed also features the MISHA Knee System, which offers an outpatient treatment option for patients who have not found relief through other therapies and are not suitable candidates for knee replacement surgery. By addressing the specific needs of osteoarthritis patients, Moximed aims to improve their quality of life while potentially delaying the need for more invasive surgical interventions. Founded in 2006, the company serves patients and medical professionals worldwide.
Twelve
Series C in 2015
Twelve manufactures medical devices. It was formerly known as Foundry Newco XII, Inc. The company was incorporated in 2009 and is based in Menlo Park, California.
NuoDB, Inc. specializes in developing a cloud-based relational database solution tailored for global applications. Its platform utilizes a memory-centric architecture that optimizes storage and replication, ensuring ACID consistency and transactional integrity across distributed databases located in multiple data centers worldwide. NuoDB's features include on-demand scalability, redundancy, policy-driven automation, and support for flexible schemas, making it suitable for various applications such as cloud migration, elastic scalability, and hybrid workloads. The database solution can be deployed on-premises, in containers, or across public, private, and hybrid clouds. NuoDB primarily serves industries such as mobile telecommunications, financial services, and interactive entertainment, along with application providers and independent software vendors. Founded in 2008 and headquartered in Cambridge, Massachusetts, NuoDB also has offices in Dublin, London, and Sofia. It operates as a subsidiary of Dassault Systèmes SE.
dlhBOWLES is a manufacturer and supplier specializing in automotive fluid management and systems components. The company designs, develops, and produces a range of products, including plastic air and fluid handling assemblies, tubing, hoses, and profile extrusions. Their offerings encompass injection molded thermoplastic parts, washer systems, camera and sensor cleaning products, as well as solutions for powertrain, chassis, and electric vehicle thermal management. Founded in 1975 and based in Canton, Ohio, dlhBOWLES has established itself as a reliable supplier to leading automakers, with a track record of over a quarter of a billion components deployed in the field. The company is committed to delivering high-quality, cost-effective solutions and has expanded its capabilities over more than fifty years to meet diverse needs across automotive, industrial, and consumer applications. Operating as a subsidiary of Bowles Fluidics Corporation, dlhBOWLES continues to innovate in fluid management technology and maintain a strong presence in the global market.
Sunlight Aerospace develops airborne wireless communication systems to provide broadband and internet services. The company focuses on creating Sunfleets, which consist of solar-powered unmanned aerial vehicles (UAVs) that feature advanced airframe designs, lightweight photovoltaic systems, and formation flight control technologies. These UAVs are engineered for high-altitude, long-endurance missions, serving as platforms for innovative airborne wireless communication networks. Sunlight Aerospace is committed to addressing the demand for solar and hybrid-powered UAVs that excel in endurance and performance, facilitating the integration of flight control, power management, and communication capabilities powered by solar energy.
Socrata, Inc. specializes in cloud-based software solutions tailored for federal, state, and local government entities, focusing on transforming data into actionable insights. The company offers a suite of services, including Open Data, which facilitates interaction with government data through visualizations and sharing; Open Performance, which aids in performance management; and Perspectives, allowing data owners to visualize and enhance their data. Additionally, Socrata provides tools like CrimeReports for law enforcement, Open Budget for exploring government budgets, Open Expenditures for transparency in spending, and Open Payroll to clarify government personnel expenses. By integrating disparate data systems on its data-as-a-service platform, Socrata enhances government program effectiveness, improves citizen engagement, and promotes accountability. Founded in 2007 and based in Seattle, Washington, Socrata operates as a subsidiary of Tyler Technologies, Inc. and is recognized for adhering to stringent government standards, having earned Federal Risk and Authorization Management Program (FedRAMP) Authority to Operate (ATO).
Miramar Labs is a company based in Sunnyvale, California, that specializes in developing medical devices for aesthetic purposes, particularly focusing on the treatment of primary axillary hyperhidrosis in adults. Founded in 2006, the company offers the miraDry System, which provides a non-invasive solution for excessive sweating and odor. This system employs microwave energy to selectively target and permanently eliminate sweat and odor glands in the underarm area. By addressing these concerns, Miramar Labs aims to enhance the confidence and quality of life for individuals suffering from this condition. However, the miraDry System is not designed to treat hyperhidrosis in other areas of the body, such as the hands and feet.
Ivantis Inc. is a medical device company based in Irvine, California, focused on developing innovative treatments for primary open-angle glaucoma. Founded in 2007, the company specializes in a minimally invasive intracanalicular scaffold that alleviates high intraocular pressure by restoring the natural outflow pathway in Schlemm's canal. This device aims to provide a less invasive and more effective solution for the over 60 million individuals worldwide affected by this condition. In addition to its primary focus on glaucoma, Ivantis intends to explore innovative treatments for other ophthalmic diseases as it expands its product offerings. The company also provides a Session Persistence Server to support clinical trials, ensuring data protection for telnet task workers and terminal emulation users across various devices and operating systems.
Principia Biopharma is a private, pre-clinical stage company initially focused on the discovery and development of differentiated small molecule drugs targeting inflammatory/autoimmune diseases as well as cancer. The company expects to submit an IND for its lead program in 2013 and continues to invest in additional programs and its reversible covalent platform.
ForSight Labs is focused on developing and applying solutions to improve the sight, care, and quality of life of visually impaired patients. Our environment is creative and collaborative; a place where entrepreneurs and investors work together to drive innovative technologies through concept, development, and ultimately commercialization in high-impact eye care companies (ForSight VISION companies). Each day millions of people rely on their vision and suffer when it is lost. There are few disabilities as impactful to quality of life as the loss of vision. The number of people with impaired vision in the US, including blindness, is expected to more than double over the next three decades. Recent estimates of the cost of vision loss in the US exceed $50 billion dollars annually. ForSight Labs brings together highly motivated and capable team members, clinicians and investors focused on starting and sustaining efforts to deliver innovative solutions to the ophthalmic community and the patients it serves.
ForSight VISION5 was founded in 2010 as the fifth company created by the ophthalmic product incubator, ForSight Labs. ForSight VISION5 is developing non-invasive products that replace eye drops and provide sustained therapy for major eye diseases including glaucoma, dry eye, and allergy. The company is currently in its second Phase 2 clinical study for its lead product, the Helios insert.
Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases. Nuvaira is currently working on a novel catheter-based system that has the potential to improve lung function, exercise capacity, and quality of life for patients with chronic obstructive pulmonary disease. It was founded in 2008 and headquartered in Minneapolis, Minnesota.
Vapotherm, Inc. is a medical technology company based in Exeter, New Hampshire, specializing in the development and commercialization of proprietary Hi-VNI technology products designed to treat patients experiencing respiratory distress. The company offers a range of Precision Flow systems, including Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic, and Precision Flow Heliox, which deliver heated, humidified, and oxygenated air at high velocities through a small-bore nasal interface. In addition to these systems, Vapotherm provides various companion products, such as the Vapotherm Transfer Unit for patient mobility, the Q50 compressor for air supply, and aerosol delivery accessories. The company aims to enhance clinical outcomes while improving patient comfort and compliance, and it primarily sells its products to hospitals through a direct sales organization in the United States and select international distributors. Founded in 1993, Vapotherm continues to focus on innovative solutions that enhance the quality of life for patients of all ages.
MuleSoft, Inc. is a provider of the Anypoint Platform, a cloud-based application integration solution that enables organizations to connect their applications, data, and devices. Founded in 2006 and headquartered in San Francisco, California, MuleSoft's platform facilitates the creation of application networks by leveraging APIs, which serve as the essential connection points for data exchange among various systems. This integration software suite allows businesses to connect both cloud-based and on-premises applications, regardless of format or source, promoting operational agility and competitive advantage. MuleSoft's offerings include self-serve infrastructure through reusable building blocks, empowering customers to efficiently compose applications tailored to their needs. The company operates as a subsidiary of Salesforce and maintains a strategic alliance with IQVIA to enhance its service offerings.
NuoDB, Inc. specializes in developing a cloud-based relational database solution tailored for global applications. Its platform utilizes a memory-centric architecture that optimizes storage and replication, ensuring ACID consistency and transactional integrity across distributed databases located in multiple data centers worldwide. NuoDB's features include on-demand scalability, redundancy, policy-driven automation, and support for flexible schemas, making it suitable for various applications such as cloud migration, elastic scalability, and hybrid workloads. The database solution can be deployed on-premises, in containers, or across public, private, and hybrid clouds. NuoDB primarily serves industries such as mobile telecommunications, financial services, and interactive entertainment, along with application providers and independent software vendors. Founded in 2008 and headquartered in Cambridge, Massachusetts, NuoDB also has offices in Dublin, London, and Sofia. It operates as a subsidiary of Dassault Systèmes SE.
Elcelyx Therapeutics, founded in 2010 and headquartered in San Diego, California, focuses on developing innovative treatments for diabetes and obesity-related metabolic disorders through its proprietary Gut Sensory Modulation (GSM) technology. The company's lead product candidate, NewMet, is designed to improve glucose metabolism by amplifying hormone release in the lower gut, thereby addressing significant unmet needs in the oral anti-diabetic market. Currently entering Phase 2b development, NewMet represents a potential breakthrough in diabetes management. Elcelyx also offers Lovidia, which targets similar metabolic issues without causing systemic side effects. The company is supported by a skilled management team, experienced investors, and a network of scientists and clinicians. In 2013, Elcelyx established NaZura BioHealth Inc. to focus on developing additional non-NewMet assets, further expanding its research and product pipeline.
HealthLoop, Inc. operates a SaaS platform that enables medical practices to monitor signs and symptoms, and communicate with patients during the recovery process. Its platform enables doctors to identify patients at risk of decline in the follow up period. The company’s platform also collects patients’ feedbacks and monitors status against expected progress; and sends alerts to physicians or providers about patients who are at risk of treatment failures, complications, or hospital readmissions. It serves medical offices in the United States. HealthLoop, Inc. was founded in 2009 and is based in Moffett Field, California.
Calithera Biosciences is a clinical-stage biopharmaceutical company based in South San Francisco, California, dedicated to discovering and developing small molecule drugs targeting tumor metabolism and immunology for cancer treatment. The company's lead candidate, CB-839, is a glutaminase inhibitor currently in Phase II clinical trials aimed at treating solid tumors. Additionally, Calithera is advancing INCB001158, an oral arginase inhibitor in Phase I/II trials for hematology and oncology. Other notable projects include CB-280, intended for cystic fibrosis treatment, and CB-708, an inhibitor of CD73. The company has established collaborations, including a license agreement with Mars, Inc. for the development of arginase inhibitors and a clinical trial partnership with Bristol-Myers Squibb to evaluate nivolumab in combination with CB-839. Founded in 2010, Calithera is focused on building a pipeline of innovative cancer therapeutics that address critical pathways necessary for tumor growth and survival.
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software tools aimed at enhancing the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company develops solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. The platform focuses on improving the hiring process for hourly workers by simplifying sourcing, screening, and onboarding, thereby increasing efficiency and engagement for both employers and employees. PeopleMatter was acquired by Snagajob in June 2016, positioning it to further enhance its offerings in the realm of hourly workforce management.
Practice Fusion, Inc. is a cloud-based electronic health records (EHR) company based in San Francisco, California, founded in 2005. The company provides a comprehensive practice management software platform that includes features such as charting, scheduling, billing, e-prescribing, lab integrations, and secure messaging. This platform is designed to connect medical professionals, patients, labs, billers, imaging centers, and life science partners, facilitating improved healthcare delivery. Additionally, Practice Fusion offers a healthcare database called Practice Fusion Insight to support medical professionals. Its services cater to a diverse range of users, including independent practices, community clinics, large medical groups, and non-profit organizations. As of February 2018, Practice Fusion operates as a subsidiary of Allscripts Healthcare Solutions.
Convo is an enterprise social collaboration platform that facilitates secure communication between desk and non-desk workers, aiming to enhance productivity and engagement within organizations. The platform distinguishes itself from traditional email and chat-based solutions by merging the simplicity of social networks with comprehensive collaboration features, allowing for streamlined work interactions without the need for email. Convo's user-friendly interface includes a newsfeed format, enabling teams to chat, upload files, highlight content, and comment efficiently. This design promotes fast, focused, and secure discussions, making it an effective tool for modern workplace communication.
Mint Bills is an application that enables its users to set reminders to pay bills. It utilizes proprietary account aggregation technology for secure payment technologies in its mobile applications. Mint Bills' primary service allows users to pay bills and track bank, credit card, investment, and loan transactions and balances through a provided mobile application. It currently has applications for iOS and Android platforms.
SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.
Socrata, Inc. specializes in cloud-based software solutions tailored for federal, state, and local government entities, focusing on transforming data into actionable insights. The company offers a suite of services, including Open Data, which facilitates interaction with government data through visualizations and sharing; Open Performance, which aids in performance management; and Perspectives, allowing data owners to visualize and enhance their data. Additionally, Socrata provides tools like CrimeReports for law enforcement, Open Budget for exploring government budgets, Open Expenditures for transparency in spending, and Open Payroll to clarify government personnel expenses. By integrating disparate data systems on its data-as-a-service platform, Socrata enhances government program effectiveness, improves citizen engagement, and promotes accountability. Founded in 2007 and based in Seattle, Washington, Socrata operates as a subsidiary of Tyler Technologies, Inc. and is recognized for adhering to stringent government standards, having earned Federal Risk and Authorization Management Program (FedRAMP) Authority to Operate (ATO).
ForSight Labs is focused on developing and applying solutions to improve the sight, care, and quality of life of visually impaired patients. Our environment is creative and collaborative; a place where entrepreneurs and investors work together to drive innovative technologies through concept, development, and ultimately commercialization in high-impact eye care companies (ForSight VISION companies). Each day millions of people rely on their vision and suffer when it is lost. There are few disabilities as impactful to quality of life as the loss of vision. The number of people with impaired vision in the US, including blindness, is expected to more than double over the next three decades. Recent estimates of the cost of vision loss in the US exceed $50 billion dollars annually. ForSight Labs brings together highly motivated and capable team members, clinicians and investors focused on starting and sustaining efforts to deliver innovative solutions to the ophthalmic community and the patients it serves.
Automatic's mission is to empower drivers with knowledge about themselves and their cars so they can be safer and drive smarter. Automatic believes that drivers should not have to buy a new car to have a better driving experience, and that the phone in their pocket can bring the future of driving to today's automobiles. Automatic is based in San Francisco, California, but its team comes from every corner of the world. The team obsesses about creating beautiful and well-engineered products that make a real difference in people's lives. Its members are big on ideas, low on ego, and love working together.
Scioderm is a privately held, clinical-stage pharmaceutical company focused on developing topical products to address critical medical needs in the treatment of chronic skin diseases.
Vapotherm, Inc. is a medical technology company based in Exeter, New Hampshire, specializing in the development and commercialization of proprietary Hi-VNI technology products designed to treat patients experiencing respiratory distress. The company offers a range of Precision Flow systems, including Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic, and Precision Flow Heliox, which deliver heated, humidified, and oxygenated air at high velocities through a small-bore nasal interface. In addition to these systems, Vapotherm provides various companion products, such as the Vapotherm Transfer Unit for patient mobility, the Q50 compressor for air supply, and aerosol delivery accessories. The company aims to enhance clinical outcomes while improving patient comfort and compliance, and it primarily sells its products to hospitals through a direct sales organization in the United States and select international distributors. Founded in 1993, Vapotherm continues to focus on innovative solutions that enhance the quality of life for patients of all ages.
MuleSoft, Inc. is a provider of the Anypoint Platform, a cloud-based application integration solution that enables organizations to connect their applications, data, and devices. Founded in 2006 and headquartered in San Francisco, California, MuleSoft's platform facilitates the creation of application networks by leveraging APIs, which serve as the essential connection points for data exchange among various systems. This integration software suite allows businesses to connect both cloud-based and on-premises applications, regardless of format or source, promoting operational agility and competitive advantage. MuleSoft's offerings include self-serve infrastructure through reusable building blocks, empowering customers to efficiently compose applications tailored to their needs. The company operates as a subsidiary of Salesforce and maintains a strategic alliance with IQVIA to enhance its service offerings.
Catalyst Biosciences, Inc. is a clinical-stage biopharmaceutical company dedicated to developing innovative treatments for hemophilia and other rare bleeding disorders. The company specializes in subcutaneous (SQ) coagulation factors designed to enhance blood clotting and improve patient outcomes compared to traditional intravenous (IV) therapies. Its product portfolio includes Marzeptacog alfa (activated), an engineered Factor VIIa that has completed Phase II development for hemophilia A or B patients with inhibitors, and Dalcinonacog alfa, a next-generation Factor IX therapy that has undergone Phase IIb clinical trials for hemophilia B. Additionally, Catalyst is developing CB 2679d-GT, a Factor IX gene therapy for hemophilia B, and CB 2782-PEG, a long-acting anti-C3 protease for dry age-related macular degeneration (AMD). The company has strategic collaborations with Mosaic Biosciences, Inc. for anti-complement factor 3 products and with Biogen International GmbH for the commercialization of pegylated CB 2782 targeting geographic atrophy associated with dry AMD. Established in 2002, Catalyst Biosciences is headquartered in South San Francisco, California.
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software tools aimed at enhancing the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company develops solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. The platform focuses on improving the hiring process for hourly workers by simplifying sourcing, screening, and onboarding, thereby increasing efficiency and engagement for both employers and employees. PeopleMatter was acquired by Snagajob in June 2016, positioning it to further enhance its offerings in the realm of hourly workforce management.
Adara is a company that provides an online audience targeting platform to help brands enhance their competitive edge in the digital marketplace. By utilizing proprietary data and audience segmentation, Adara offers actionable insights that guide business planning and improve consumer engagement. The platform enables travel brands and advertisers to gain a comprehensive understanding of their audience by analyzing real customer data. This allows advertisers to tailor their offerings and effectively reach specific audiences based on their buying habits, ultimately facilitating more personalized marketing strategies.
Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases. Nuvaira is currently working on a novel catheter-based system that has the potential to improve lung function, exercise capacity, and quality of life for patients with chronic obstructive pulmonary disease. It was founded in 2008 and headquartered in Minneapolis, Minnesota.
OptiScan Biomedical Corporation specializes in developing advanced glucose monitoring systems for use in intensive care units. The company is known for its OptiScanner 5000, an automated bedside platform that provides precise plasma-based glucose measurements using spectroscopy technology, eliminating the need for calibration. This system enables healthcare providers to monitor and respond to changes in glucose levels for critically ill patients effectively. Founded in 1994 and headquartered in Hayward, California, OptiScan Biomedical faced financial challenges, filing for Chapter 11 bankruptcy in June 2020 and subsequently converting to Chapter 7 bankruptcy in November 2020.
R2 Semiconductor, Inc. is a fabless power management company based in Sunnyvale, California, founded in 2008. The company specializes in low-voltage transistors and develops innovative power management technologies aimed at reducing power consumption and heat dissipation in various applications. Its product lineup includes FasTrack, designed for envelope tracking, and FastLane, which optimizes power management for multi-core application processors and digital System on Chips (SoCs). R2 Semiconductor's solutions enhance frequency switching, bandwidth, and size efficiency, catering to the needs of clients requiring effective power management for high-voltage applications.
RelateIQ, now known as SalesforceIQ, is a provider of a professional relationship management platform designed to enhance customer relationship management. The platform automatically captures communication data from various sources, including email, phone calls, calendars, and social networks, allowing users to manage and analyze their interactions with sales prospects effectively. By leveraging advanced data science capabilities, RelateIQ delivers valuable insights that help users close deals more efficiently. The platform is accessible across multiple devices, including mobile applications and browser extensions, facilitating collaboration among teams. Ultimately, RelateIQ aims to drive revenue growth while streamlining workflows, making the sales process more efficient and less burdensome for its users.
Calithera Biosciences is a clinical-stage biopharmaceutical company based in South San Francisco, California, dedicated to discovering and developing small molecule drugs targeting tumor metabolism and immunology for cancer treatment. The company's lead candidate, CB-839, is a glutaminase inhibitor currently in Phase II clinical trials aimed at treating solid tumors. Additionally, Calithera is advancing INCB001158, an oral arginase inhibitor in Phase I/II trials for hematology and oncology. Other notable projects include CB-280, intended for cystic fibrosis treatment, and CB-708, an inhibitor of CD73. The company has established collaborations, including a license agreement with Mars, Inc. for the development of arginase inhibitors and a clinical trial partnership with Bristol-Myers Squibb to evaluate nivolumab in combination with CB-839. Founded in 2010, Calithera is focused on building a pipeline of innovative cancer therapeutics that address critical pathways necessary for tumor growth and survival.
Kona Medical, Inc. is a medical technology company founded in 2009 and based in Issaquah, Washington. It specializes in the development of a non-invasive ultrasound-based therapy system aimed at treating hypertension, particularly in patients with drug-resistant hypertension. The company's flagship product, Surround Sound, utilizes ultrasound imaging to precisely guide the application of focused ultrasound energy for renal denervation, targeting the nerves connected to the kidneys to help regulate blood pressure. By offering a less invasive alternative to traditional treatments, Kona Medical seeks to address the health risks associated with high blood pressure while improving patient outcomes through advanced therapeutic techniques.
Big Switch Networks Inc. specializes in data center networking technologies aimed at enhancing operational efficiency and agility for organizations worldwide. Founded in 2010 and headquartered in Santa Clara, California, the company offers a range of solutions including the Big Monitoring Fabric, which serves as a network packet broker for security chaining and visibility, and the Big Cloud Fabric, a software-defined networking solution compatible with various cloud environments such as VMware and OpenStack. These products facilitate improved networking capabilities in on-premises, public, and multi-cloud settings. Big Switch Networks has established partnerships with industry leaders like Dell EMC and HPE, and actively contributes to open-source networking communities. The company also has operations in Japan and maintains a presence in over 25 countries, reinforcing its commitment to providing innovative networking solutions.
Principia Biopharma is a private, pre-clinical stage company initially focused on the discovery and development of differentiated small molecule drugs targeting inflammatory/autoimmune diseases as well as cancer. The company expects to submit an IND for its lead program in 2013 and continues to invest in additional programs and its reversible covalent platform.
Promedior, Inc. is a clinical-stage biotechnology company based in Lexington, Massachusetts, focused on developing therapeutics for rare fibrotic and inflammatory diseases. The company’s primary targets include conditions such as myelofibrosis, idiopathic pulmonary fibrosis, age-related macular degeneration, and diabetic retinopathy. Promedior's drug portfolio features PRM-151, a recombinant form of human pentaxin-2 protein, and PRM-167, a variant designed for intravitreal delivery. These therapeutics are aimed at regulating monocyte-derived cell populations, which are critical in fibrotic, inflammatory, and autoimmune diseases. By specifically addressing these cells at injury sites, Promedior seeks to promote tissue healing and minimize systemic side effects commonly associated with existing therapies. The company was incorporated in 2006 and was previously known as Fibrotix, Inc.
Catalyst Biosciences, Inc. is a clinical-stage biopharmaceutical company dedicated to developing innovative treatments for hemophilia and other rare bleeding disorders. The company specializes in subcutaneous (SQ) coagulation factors designed to enhance blood clotting and improve patient outcomes compared to traditional intravenous (IV) therapies. Its product portfolio includes Marzeptacog alfa (activated), an engineered Factor VIIa that has completed Phase II development for hemophilia A or B patients with inhibitors, and Dalcinonacog alfa, a next-generation Factor IX therapy that has undergone Phase IIb clinical trials for hemophilia B. Additionally, Catalyst is developing CB 2679d-GT, a Factor IX gene therapy for hemophilia B, and CB 2782-PEG, a long-acting anti-C3 protease for dry age-related macular degeneration (AMD). The company has strategic collaborations with Mosaic Biosciences, Inc. for anti-complement factor 3 products and with Biogen International GmbH for the commercialization of pegylated CB 2782 targeting geographic atrophy associated with dry AMD. Established in 2002, Catalyst Biosciences is headquartered in South San Francisco, California.
Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases. Nuvaira is currently working on a novel catheter-based system that has the potential to improve lung function, exercise capacity, and quality of life for patients with chronic obstructive pulmonary disease. It was founded in 2008 and headquartered in Minneapolis, Minnesota.
Doximity is a digital platform designed for medical professionals in the United States, serving over 70% of physicians across various specialties and practice areas. The platform offers a range of tools that facilitate collaboration and communication among healthcare providers, allowing them to securely coordinate patient care and conduct virtual visits. Additionally, Doximity helps its members stay informed with the latest medical news and research while providing resources for career management. The company's mission focuses on enhancing the productivity of doctors to ultimately improve healthcare delivery for patients.
ForSight VISION5 was founded in 2010 as the fifth company created by the ophthalmic product incubator, ForSight Labs. ForSight VISION5 is developing non-invasive products that replace eye drops and provide sustained therapy for major eye diseases including glaucoma, dry eye, and allergy. The company is currently in its second Phase 2 clinical study for its lead product, the Helios insert.
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