MorphoSys

Human Immunology Biosciences is a biotechnology company dedicated to developing therapies for immune-mediated diseases, particularly autoimmune and inflammatory conditions. The company specializes in precision medicine and focuses on discovering and creating transformative therapies. Its lead product, felzartamab, is a fully human anti-CD38 monoclonal antibody that has demonstrated the ability to deplete CD38+ cells, including plasma cells and natural killer cells, in clinical studies. This mechanism may enhance clinical outcomes across a range of immune-mediated diseases, offering improved treatment options for patients suffering from these conditions.

Constellation Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing innovative therapeutics for cancers linked to abnormal gene expression and drug resistance. The company specializes in the field of epigenetics, targeting selective regulators of epigenetic function that are vital for gene expression control. Its lead product candidates include CPI-0610, currently in Phase II clinical trials for myelofibrosis in combination with ruxolitinib, and CPI-1205, which is undergoing Phase Ib/II clinical trials for metastatic castration-resistant prostate cancer alongside androgen receptor signaling inhibitors. Additionally, Constellation is advancing CPI-0209, which is in the dose escalation phase of a Phase I/II clinical trial aimed at treating solid tumors. Founded in 2008 and based in Cambridge, Massachusetts, the company was previously known as Epigenetix, Inc. before rebranding in March 2008.

Adivo GmbH is a veterinary biotechnology company based in Planegg, Germany, that specializes in the development of species-specific therapeutic antibodies for companion animals, particularly dogs. The company focuses on addressing serious diseases in pets and aims to extend its therapeutic offerings to other animal species. Adivo utilizes a fully synthetic, dog-specific drug library to select antibodies with optimal properties through phage display technology. As a spin-off of MorphoSys AG, Adivo benefits from extensive expertise in the development of human therapeutic antibodies, which the team applies to advance veterinary medicine.

Lanthio Pharma B.V. is a biopharmaceutical company based in Groningen, the Netherlands, specializing in the discovery and development of lantipeptide drugs aimed at treating conditions such as fibrosis, stroke, heart failure, and multiple sclerosis. The company employs its proprietary lanthionine-peptide drug discovery technology, LanthioPep™, to create novel peptide therapeutics that exhibit enhanced resistance to peptidase degradation and high receptor specificity. Among its product pipeline are LP2, designed to target fibrosis; PanCyte, intended for ischemic stroke recovery and related conditions; a Lanthi-apelin agonist for various organ systems; and Lanthi-galanin for multiple sclerosis. Founded in 2010, Lanthio Pharma operates as a subsidiary of Morphosys AG, focusing on generating stable, peptidase-resistant peptides that possess high intrinsic activity for several G-protein-coupled receptor targets.

Sloning BioTechnology specializes in the synthesis of DNA molecules through its innovative and patented Slonomics technology platform. This platform enables the production of DNA with unique features, including enhanced sequence limitations, reliability, and cost-effectiveness, all achieved on an industrial scale using automated robotic systems. In addition to gene synthesis, Sloning BioTechnology offers a range of synthetic biology tools, positioning itself as a key player in the field of biotechnology.