Norgine Ventures

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Inovus Ltd specializes in designing and manufacturing medical simulation products aimed at enhancing surgical training. Founded in 2012 and based in Saint Helens, United Kingdom, the company offers a range of simulators, including take-home and institutional laparoscopic simulators. These products are specifically developed to teach essential surgical skills, such as laparoscopic appendectomy and cholecystectomy, as well as competencies in critical care and medicine. Inovus Ltd caters to its customers primarily through online channels, providing accessible and versatile training solutions for surgical trainees and residents to improve their skills and ultimately enhance patient care.

Magentiq Eye Ltd., a medical device company, which provides products for endoscopic medical procedures. The company offers automatic polyp detection system (APDS); APDS- RT, a software that runs on local device and server and gets the video feed from the endoscopic camera used by the physician in real time; and APDS-OFL, a software that runs in offline mode on pre-recorded colonoscopy videos. It also provides big data management and analysis, computer vision, video analysis, and colonoscopy screening test. The company was founded in 2014 and is based in Haifa, Israel.

ImaginAb, Inc. is a clinical-stage biotechnology company specializing in immune oncology imaging, with a focus on enhancing precision medicine for cancer treatment. Founded in 2007 and based in Inglewood, California, the company develops engineered antibody fragments known as minibodies, which are designed for diagnostic imaging using Positron Emission Tomography (PET). ImaginAb's portfolio includes precision imaging products targeting CD8 and CD4 for immune-oncology applications, as well as PSMA PET for prostate cancer diagnostics. By creating highly targeted diagnostic imaging agents that retain the specificity of parental antibodies while being optimized for clinical use, ImaginAb addresses critical needs in patient selection and treatment monitoring for cancer immunotherapy.

Magentiq Eye Ltd., a medical device company, which provides products for endoscopic medical procedures. The company offers automatic polyp detection system (APDS); APDS- RT, a software that runs on local device and server and gets the video feed from the endoscopic camera used by the physician in real time; and APDS-OFL, a software that runs in offline mode on pre-recorded colonoscopy videos. It also provides big data management and analysis, computer vision, video analysis, and colonoscopy screening test. The company was founded in 2014 and is based in Haifa, Israel.

PathoQuest SAS is a biotechnology company based in Paris, France, focused on advancing pathogen detection through a metagenomics approach. Founded in 2010 as a spin-off from Institut Pasteur, the company utilizes proprietary next-generation sequencing (NGS) technology to provide actionable reports for clinicians, biologists, and biopharmaceutical professionals. PathoQuest’s offerings include the iDTECTTM Dx Blood test for pathogen identification and a comprehensive database that enhances diagnostic accuracy. Additionally, the company provides Viral Safety testing services specifically designed for biopharmaceutical firms, which has quickly established a revenue stream from major industry players. The integration of advanced sample preparation and cloud-based bioinformatics enables improved detection capabilities across various biological samples, allowing healthcare professionals to address the limitations of traditional infectious agent detection methods.

SpineGuard SA specializes in the design, development, and marketing of medical devices for spinal surgery, with a focus on enhancing the safety and precision of pedicle screw placement. The company's flagship product line, PediGuard, includes various probes such as the PediGuard Straight, Curved, and Cannulated, designed to facilitate screw placement while minimizing radiation exposure during procedures. Additionally, SpineGuard offers the DSG Connect app for signal collection during drilling and the DSG smart screw for efficient screw placement. Founded in 2009 and headquartered in Vincennes, France, SpineGuard aims to establish PediGuard as the standard of care in spinal surgery, benefiting patients, surgeons, and healthcare providers. The company continues to explore further applications of its technology to align with its mission of improving surgical outcomes.

Caresyntax Inc. develops a technology platform specializing in surgical analytics to enhance safety and efficiency in hospitals and ambulatory surgical centers. The company offers solutions designed to identify and manage risks, automate workflows, and reduce variability in surgical procedures. Its flagship products include qvident, a performance management software that enables surgical teams to create and share surgical content, and PRIME365, an integration platform that consolidates key surgical data from various sources such as video, audio, patient vitals, and procedural timestamps. Caresyntax's offerings support a range of surgical procedures, from minimally invasive to robotic surgeries, and can be deployed as HIPAA-compliant software through on-premise, cloud-based, or hybrid installations. Established in 1991, Caresyntax is headquartered in Boston, Massachusetts.

EBS Technologies GmbH, founded in 2007 and headquartered in Hennigsdorf, Germany, specializes in developing and commercializing medical devices aimed at treating neurologically induced impairments, particularly visual field loss. The company offers EBS Therapy, a non-invasive optic nerve stimulation treatment that utilizes low-voltage electrical currents to promote neuroregeneration and neuroprotection. This therapy targets conditions resulting from stroke, traumatic brain injury, and glaucoma, among others. With over 15 years of research and clinical experience involving more than 1,200 patients, EBS Technologies has demonstrated through double-blind, randomized studies and clinical observations that its therapy can help partially restore vision in affected individuals. The company received the CE Mark for its stimulation device in 2013 and commenced commercial treatments in 2014. Currently, there are eight EBS Treatment centers operating across Germany, with plans to expand the network further.

Collagen Solutions is a global provider of medical-grade collagen components and biomaterials, primarily for applications in regenerative medicine, medical devices, and in-vitro diagnostics. The company specializes in developing and manufacturing a range of collagen products, including soluble collagen, powders, fibrillars, gels, and freeze-dried formulations, which are utilized in various medical fields such as orthopaedics, dental care, cardiovascular procedures, and wound management. Additionally, Collagen Solutions offers Bovine Pericardium for bio-prosthetic heart valves and surgical applications. The company supports pharmaceutical and medical device sectors by providing product development and contract manufacturing services, including technology transfer and regulatory assistance. Founded in 2013 and based in London, Collagen Solutions aims to foster long-term commercial relationships by collaborating closely with customers throughout product development and regulatory processes.

PulseCath is a medical device company, develops, manufactures, and markets circulatory support systems to cardiologists and cardiac surgeons in the Netherlands and internationally. It offers iVAC 3L, a mid-range minimal heart circulatory assist device that generates up to three liters per minute, and offers critical hemodynamic support in the case of left ventricular failure or during high-risk revascularization procedures with potential post cardiotomy weaning complications.

Q3 Medical Devices Limited is an Irish holding company, established in 2013 and based in Dublin, that specializes in the development, manufacturing, and distribution of minimally invasive medical devices. The company's focus is on creating solutions for the treatment of patients with cardiology, peripheral vascular, and non-vascular diseases. With operations that extend into Germany, Q3 Medical Devices aims to enhance its product offerings by acquiring medical device businesses that generate annual revenues between 1 to 10 million. The company employs patented micro-invasive technology to minimize incision sizes during procedures, thereby reducing complication rates and facilitating safer surgeries. Through its strategic initiatives, Q3 Medical Devices is committed to expanding its manufacturing capabilities and distribution channels in the medical device sector.

SpineVision is a spinal technology company focused on the development and marketing of implants and instrumentation for spinal treatment. The company offers spinal systems addressing a wide range of spinal pathologies including degenerative disc disease, deformity, cervical disorders, trauma and tumors. These products have been developed in collaboration with leading neurological and orthopedic surgeons which has resulted in over 20 patents. SpineVision was founded in 1999 and is headquartered in Antony in France, with subsidiaries in Belgium, Italy, the United Kingdom, and the United States.

Azanta A/S is a biopharmaceutical company based in Copenhagen, Denmark, founded in 1994. The company specializes in developing and marketing treatments for orphan oncology and women's health conditions, along with offering products related to obstetrics and addiction medicine. Azanta's product portfolio includes several pharmaceuticals such as Nimorazole, a hypoxic radiosensitizer for head and neck cancer, and Angusta, used for labor induction. Other notable products include Amnisure, Cicatridina, Repadina Plus, Cystistat, Flexi-T, Methadone, Oxandrin, and Suplasyn. In February 2010, the company changed its name from IPC International A/S and has since operated as a subsidiary of Norgine B.V. Azanta aims to provide effective healthcare solutions in its specialized areas.

Agendia's molecular diagnostic technology provides cancer patients and their physicians with a glimpse into their genome, answers to the most pressing questions and enables personalized treatment plans. Agendia’s breast cancer tests were developed using an unbiased gene selection by analyzing the complete human genome. Agendia’s tests can help physicians assess a patient’s individual risk for metastasis, which patients may benefit from chemo, hormonal or combination therapy, and which patients may not require these treatments and can instead be treated with other, less arduous and less costly methods.

SuperSonic Imagine SA operates as a medical technology company. It designs, develops, and markets Aixplorer, an ultrasound system. It has developed a technology that offers practitioners and patients a breakthrough in the diagnosis and follow up of breast, prostate, and thyroid cancers, as well as liver diseases. The company’s products include Aixplorer, an ultrasound system that renders images with exceptional definition, contrast, and resolution. It operates primarily in China, the United States, and France. The company was founded in 2005 and is headquartered in Aix-en-Provence, France. SuperSonic Imagine SA is a subsidiary of Hologic Hub Ltd.

Stanmore Implants Worldwide Ltd. specializes in the design and manufacture of orthopedic implant systems for both juvenile and adult patients, with a focus on orthopedic oncology and complex primary and revision cases affecting the upper limb, lower limb, and pelvis. The company offers a range of adult reconstructive solutions, including modular implant systems for the femur and knee, as well as patient-specific implants tailored for oncology and complex cases. Its juvenile offerings include extendible prostheses designed to accommodate growth. Stanmore Implants is recognized for its innovative approach, which includes a custom implant service and the advancement of robotic bone preparation technology acquired through the purchase of Acrobot. Founded in 1949 and headquartered in Elstree, United Kingdom, Stanmore Implants operates as a subsidiary of Stryker Corporation.

Internis Pharmaceuticals Ltd. is a pharmaceutical company based in London, United Kingdom, founded in 2010. The company specializes in the development, manufacture, and supply of prescription vitamin D medicines specifically for the UK market. Its product portfolio includes various formulations of FULTIUM-D3, available in different strengths and forms, as well as ACCRETE-D3, which combines calcium and vitamin D3. These medicines are aimed at preventing and treating common bone disorders such as osteoporosis and vitamin D deficiency, conditions that affect a significant portion of the population. Internis Pharmaceuticals focuses on providing effective solutions to healthcare professionals and patients, addressing the health risks associated with vitamin D deficiency, which can lead to various complications including bone deformities and weakened immune function.

SpineGuard SA specializes in the design, development, and marketing of medical devices for spinal surgery, with a focus on enhancing the safety and precision of pedicle screw placement. The company's flagship product line, PediGuard, includes various probes such as the PediGuard Straight, Curved, and Cannulated, designed to facilitate screw placement while minimizing radiation exposure during procedures. Additionally, SpineGuard offers the DSG Connect app for signal collection during drilling and the DSG smart screw for efficient screw placement. Founded in 2009 and headquartered in Vincennes, France, SpineGuard aims to establish PediGuard as the standard of care in spinal surgery, benefiting patients, surgeons, and healthcare providers. The company continues to explore further applications of its technology to align with its mission of improving surgical outcomes.

Medical Vision AB develops, constructs, and produces medical devices used during endoscopic procedures. It offers arthro-tube products, arthroscopy pumps, arthroscopy sets, receptacles, digital camera systems, capture devices, fluid management systems, and double pumps.