North Coast Venture

North Coast Ventures, previously known as North Coast Angel Fund, is a Cleveland-based private equity firm established in 2006 that focuses on early-stage technology investments. The firm comprises four contributed capital funds and is supported by a network of prominent investors, entrepreneurs, and business leaders from Ohio. Members of North Coast Ventures actively contribute by generating deal flow, participating in due diligence, and collaborating with portfolio companies. The firm aims to foster a supportive environment for its investments, enhancing the performance of its funds. By being the region's first professionally managed angel fund, North Coast Ventures seeks to improve the early-stage funding landscape for both entrepreneurs and investors in Northeast Ohio, where there has been a historical tradition of angel investing.

Ann Kirschner

Chief Financial Officer

Daniel Luketic

Director

Claiborne Read Rankin

Managing Director

79 past transactions

Bloomfilter

Seed Round in 2023
Bloomfilter is a developer of an enterprise software planning application. Bloomfilter helps software executives and leaders illuminate the path to software project success through our platform.

Because Intelligence

Seed Round in 2022
We're a team of Marketers, Brand Experts, Data Scientists, and Engineers, with a passion for changing how Marketers start conversations with their consumers. We're tackling the massive problem virtually every consumer brand faces today: 64% of consumers will choose, avoid, switch, or boycott a brand based on its stand on societal issues they care about. Today's generation of consumers is the most disloyal in history. Why? Because they won't stay loyal just based off products, unlike their parents before them. They insist on buying from socially responsible brands that stand for the causes they support. We're solving for this through the Because SaaS Belief Marketing Platform. Because helps the 80% of U.S. consumer businesses who give back to charity, to build long-term brand differentiation with their consumers through belief-based social media engagement, rather than product advertising. How it works: Because uses proprietary machine learning algorithms to produce a daily curation of the highest quality "matches"​ for Marketing teams to organically engage their ideal influencers, who are live on social talking about the same social causes their brand supports. Then they can share their story out with their network, and give you an opportunity to expose your brand to potential customers through common beliefs. And eventually, turn them into loyal customers. Because helps Marketing teams reduce customer acquisition costs by moving away from paid influencer engagements and product-driven advertising, to organic Because engagements with micro-influencers who just so happen to already love the causes you love. We'd love to meet new customers, talent, and investors. Reach out to us at learn@becauseintelligence.com

Vytalize

Series B in 2022
Vytalize Health Inc. is a healthcare service provider based in Hoboken, New Jersey, established in 2014. The company focuses on supporting independent primary care physicians participating in value-based care, particularly with Medicare. Vytalize offers a comprehensive suite of services, including primary care, chronic care management for various conditions such as hypertension and diabetes, behavioral health, care coordination, and in-home care. Its innovative enablement platform enhances patient-physician relationships through data-driven and personalized care, allowing healthcare providers to manage chronic conditions effectively. By integrating technology and unique value-based arrangements, Vytalize aims to improve patient outcomes and optimize care delivery across nine states.

Bubble Insurance

Pre Seed Round in 2022
Provider of digitally bundled insurance services intended to protect assets and lives. The company's services seamlessly bundle life insurance with homeowner insurance when users buy a house or refinance their mortgage, enabling homeowners and homebuyers to protect their families from unexpected events.

Wizest

Pre Seed Round in 2021
Developer of a saving and investing platform designed to democratize access to financial advisors and make investing sustainable. The company's platform allows it to draft a team of advisors as per user selection, it replicates its virtual portfolio on its behalf, enabling customers to diversify investment strategies, as well as a learning and engaging experience through its gamified environment.

Alviere

Series B in 2021
Developer of an embedded finance platform designed to empower brands to offer financial services to their customers. The company's software and services give businesses a flexible framework to launch new financial service lines of business aimed at increasing profits, enabling customer relationships and insights, and increasing customer satisfaction and retention.

Axuall

Series A in 2021
Axuall, Inc. provides digital network for verifying identity, credentials, and authenticity to healthcare, insurance, financial services, government, philanthropy, manufacturing, logistics, transportation, security, aviation, and construction sectors. The company was incorporated in 2018 and is headquartered in Cleveland, Ohio.

Thrivable

Seed Round in 2021
Thrivable is a technology platform that helps health care organizations tap into a comprehensive patient database to do market research activities. Right now the market research process is slow, expensive, and frustrating for companies. Thrivable has created a solution that reduces the time it takes to get insights from months to hours.

ReadySet Surgical

Series A in 2020
ReadySet Surgical LLC is a company that develops a cloud-based dashboard software solution designed to coordinate surgical vendor inventory, thereby simplifying the surgical vendor supply chain. The platform enhances logistics and communication among all members of the surgical team, ensuring that each procedure is equipped with the correct contracted inventory and complete documentation. Additionally, ReadySet Surgical offers RS Analyze, a tool that enables hospitals to assess vendor performance and identify off-contract implant purchases through real-time data, facilitating timely corrective actions. The company provides 24/7 technology support services to hospital staff and vendor representatives, emphasizing ease of installation and a strong user experience. Founded in 2015 and based in Cincinnati, Ohio, ReadySet Surgical is built on a team with extensive experience in operating room dynamics, central sterilization, and medical device manufacturing.

Remesh

Series A in 2020
Remesh Inc. operates an AI-powered online platform that facilitates live conversations with large groups of people, allowing users to engage with up to 1,000 participants simultaneously. Founded in 2013 and based in the United States, Remesh enables organizations to gather and analyze audience responses in real-time. This capability helps businesses understand their customers or employees better, leading to more informed decision-making. By providing a space for collective input, Remesh represents the collective thinking of diverse groups, enhancing communication and collaboration.

S4 Medical

Venture Round in 2020
S4 Medical Corp is a medical device company based in Cleveland, Ohio, founded in 2017. The company specializes in developing innovative solutions for catheter ablation treatment of atrial fibrillation. Its flagship product, the eSolution device, is designed to reduce complications to the esophagus during these procedures, enhancing patient safety and outcomes. S4 Medical focuses on addressing the challenges associated with cardiac procedures by providing effective protective measures during catheter ablation.
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

Axuall

Seed Round in 2019
Axuall, Inc. provides digital network for verifying identity, credentials, and authenticity to healthcare, insurance, financial services, government, philanthropy, manufacturing, logistics, transportation, security, aviation, and construction sectors. The company was incorporated in 2018 and is headquartered in Cleveland, Ohio.

MedPilot

Seed Round in 2019
MedPilot is a tool designed to make healthcare billings & collections departments more effective and efficient. Our software uses data science and behavioral targeting to recommend patient engagement methods, personalize communications and resolve outstanding balances. MedPilot’s analytics reporting can also increase the productivity of in-house & third party call centers. A Techstars Company

TPA Stream

Seed Round in 2019
TPA Stream provides cloud based software that targets Third Party Administrators and their challenges in managing EOBs (explanation of benefits). TPA Stream harvests EOBs for both and large and small employers and provides a portal for ease of management and automated submission to benefit administration software.TPA Stream was founded in 2014 to make health benefits easier for employees and administrators. After years of experience at various software and healthcare related companies, the three founders of TPA Stream came together to initially make Health Reimbursement Arrangements (HRAs) easier for employees.
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

Alviere

Series A in 2018
Developer of an embedded finance platform designed to empower brands to offer financial services to their customers. The company's software and services give businesses a flexible framework to launch new financial service lines of business aimed at increasing profits, enabling customer relationships and insights, and increasing customer satisfaction and retention.

Mezu

Venture Round in 2018
Mezu is a mobile payment app that gives you a private and secure way to give and get money without sharing your personal information. Just like cash, with Mezu, you can conveniently pay, tip, earn and donate safely and for free. Because Mezu believes that what you do with your money is your business. Mezu is now available on iOS and Android in the United States. Sign up and learn more: https://www.mezu.com.

Standard Bariatrics

Series A in 2018
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in the development of surgical instruments designed for weight loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products is the Standard Clamp, which assists surgeons in standardizing their techniques to minimize variation, enhance efficiency, and reduce waste during procedures. Additionally, the company's disposable surgical tools complement general-use endoscopic staplers, allowing surgeons to decrease the number of cartridges used in surgeries and ultimately lowering costs. Through these innovations, Standard Bariatrics aims to improve surgical outcomes and streamline the weight loss surgery process.

S4 Medical

Seed Round in 2018
S4 Medical Corp is a medical device company based in Cleveland, Ohio, founded in 2017. The company specializes in developing innovative solutions for catheter ablation treatment of atrial fibrillation. Its flagship product, the eSolution device, is designed to reduce complications to the esophagus during these procedures, enhancing patient safety and outcomes. S4 Medical focuses on addressing the challenges associated with cardiac procedures by providing effective protective measures during catheter ablation.

Wisr

Seed Round in 2017
Wisr Inc. operates an online platform that enables alumni to guide current students through automated matching, scheduling, and follow up communications. Its platform strengthens the work of career services and alumni relations offices for better career outcomes. The company was founded in 2016 and is based in Rocky River, Ohio.
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

Vlipsy

Seed Round in 2017
Vlipsy, Inc. is a startup based in Canton, Ohio, that specializes in providing a platform for short, conversational video clips. Founded in 2017 by Nickless and Co-founder Matt Tew, the company offers users a way to search, watch, and create video clips that can be shared in online communications through its mobile application. Unlike traditional GIFs, Vlipsy’s clips include sound, enhancing the user experience. The platform allows users to create accounts and access a variety of clips from their favorite internet videos. Additionally, Vlipsy offers an API that facilitates third-party integrations, making it compatible with popular communication tools such as Slack, Skype, Viber, Telegram, and Kik. The innovative approach of combining video and audio has helped Vlipsy gain traction among users looking for engaging ways to communicate online.

Able (formerly EmployStream)

Seed Round in 2017
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

Wisr

Seed Round in 2017
Wisr Inc. operates an online platform that enables alumni to guide current students through automated matching, scheduling, and follow up communications. Its platform strengthens the work of career services and alumni relations offices for better career outcomes. The company was founded in 2016 and is based in Rocky River, Ohio.

Remesh

Seed Round in 2017
Remesh Inc. operates an AI-powered online platform that facilitates live conversations with large groups of people, allowing users to engage with up to 1,000 participants simultaneously. Founded in 2013 and based in the United States, Remesh enables organizations to gather and analyze audience responses in real-time. This capability helps businesses understand their customers or employees better, leading to more informed decision-making. By providing a space for collective input, Remesh represents the collective thinking of diverse groups, enhancing communication and collaboration.

NaviStone

Seed Round in 2016
NaviStone is a technology company based in Cincinnati, Ohio, that specializes in website visitor and behavior tracking to enhance direct marketing efforts. Its flagship product, NaviStone Prospecting, allows marketers to identify and match previously anonymous website visitors with postal names and addresses, enabling targeted direct mail campaigns. By analyzing online browsing behavior, NaviStone identifies prospective customers exhibiting "intent to buy," which supports customer acquisition and reactivation initiatives. The company's innovative approach includes a unique double-blind system, ensuring the anonymity of website visitors while facilitating effective retargeting through individualized direct mail. NaviStone serves a diverse range of industries, including nonprofit, consumer goods, publishing, retail, and financial services, providing clients with a responsive marketing channel that leverages online intent data to drive demand shortly after consumer engagement.

StreamLink Software

Venture Round in 2016
StreamLink Software is a Software-as-a-Service company that specializes in grant management solutions for nonprofits and the public sector. Founded in 2008 and headquartered in Cleveland, Ohio, the company offers a comprehensive platform named AmpliFund, which facilitates the management of all stages of the grant lifecycle. AmpliFund aims to enhance operational capacity and efficiency by automating grant compliance and standardizing data processes. Through its innovative software, StreamLink Software supports organizations in navigating the complexities of grant management effectively.

Ahalogy

Series B in 2015
Ahalogy is the Passion to Purchase Platform™. Brands and agencies tap into Ahalogy to grow users and use occasions by connecting with their consumers’ interests. We deliver proven ROI through our category trend data, authentic influencer content, and social optimization technology. Ahalogy is an official Pinterest Marketing Partner, and works with other leading social networks. Ahalogy is headquartered in Cincinnati, OH, the global capital of brand marketing, with additional offices in New York, Chicago, Los Angeles, and San Francisco.

Complion

Venture Round in 2015
Complion Inc. is a developer of a web-based document and workflow management platform tailored for clinical research sites, academic medical centers, hospitals, health systems, and contract research organizations. The platform enables secure and compliant management of regulatory documents and administrative tasks, providing features such as document tracking, e-signatures, and real-time compliance insights. It facilitates various aspects of clinical trials, including study startup, amendment processing, safety reporting, and training, while ensuring high data security. Complion's solutions streamline information for auditors and quality assurance personnel, enhancing collaboration among researchers and sponsors. The company also offers customer support, training resources, and a searchable online help center to assist users. Founded in 2012 and headquartered in Cleveland, Ohio, Complion was previously known as RegBinder, Inc. before rebranding in 2013.

Petbrosia

Venture Round in 2015
Petbrosia, Inc. is a Cincinnati-based company that specializes in providing custom dog and cat food designed to meet the unique nutritional needs of individual pets. Founded in 2012, the company offers a range of grain-free options, including salmon and chicken, along with fruits and vegetables. Petbrosia utilizes an innovative e-commerce platform combined with a manufacturing and logistics system to deliver tailored pet food that supports the ideal body condition of pets. The company's mission is to enhance the wellbeing of dogs, cats, and their owners by offering products that cater to the specific dietary requirements of pets.
Capture Education provides a cloud-based k-12 school scheduling software “ScheduleSMART”. ScheduleSMART is the leading automation engine for class scheduling and recommendations, driving staffing and classroom efficiencies as well as student pathways toward progression, graduation and college readiness. Initially launched in 2012, this software platform now counts over 200 subscription clients representing over 1 million end users. Clients include such notable school districts as 20% of all New York City high schools, 30% of all Ohio middle schools and high schools, Houston ISD, Gwinnett County (Georgia), Baltimore County Schools, Seminole County (Florida), and Grand Prairie ISD (Texas).

Public Insight

Venture Round in 2014
Public Insight Corporation was founded in 2012 with the mission of bringing relevance, insight, and clarity to public data. The company believes that public data should always be in an easy-to-understand and analyze format. It serves both constituents, businesses, and governments alike, with the end goal of increasing communication and clarity between both the organization and the citizen.

Neuros Medical

Series B in 2014
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies to address unmet medical needs for patients globally. The company’s flagship technology, Electrical Nerve Block, targets the elimination of chronic pain associated with various conditions, including neuroma, residual limb pain, chronic post-surgical pain, and chronic migraines. Additionally, Neuros Medical offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices designed to enhance treatment outcomes. Founded in 2008, the company aims to provide innovative solutions for chronic pain management.
Capture Education provides a cloud-based k-12 school scheduling software “ScheduleSMART”. ScheduleSMART is the leading automation engine for class scheduling and recommendations, driving staffing and classroom efficiencies as well as student pathways toward progression, graduation and college readiness. Initially launched in 2012, this software platform now counts over 200 subscription clients representing over 1 million end users. Clients include such notable school districts as 20% of all New York City high schools, 30% of all Ohio middle schools and high schools, Houston ISD, Gwinnett County (Georgia), Baltimore County Schools, Seminole County (Florida), and Grand Prairie ISD (Texas).

StreamLink Software

Series A in 2014
StreamLink Software is a Software-as-a-Service company that specializes in grant management solutions for nonprofits and the public sector. Founded in 2008 and headquartered in Cleveland, Ohio, the company offers a comprehensive platform named AmpliFund, which facilitates the management of all stages of the grant lifecycle. AmpliFund aims to enhance operational capacity and efficiency by automating grant compliance and standardizing data processes. Through its innovative software, StreamLink Software supports organizations in navigating the complexities of grant management effectively.

Ahalogy

Series A in 2014
Ahalogy is the Passion to Purchase Platform™. Brands and agencies tap into Ahalogy to grow users and use occasions by connecting with their consumers’ interests. We deliver proven ROI through our category trend data, authentic influencer content, and social optimization technology. Ahalogy is an official Pinterest Marketing Partner, and works with other leading social networks. Ahalogy is headquartered in Cincinnati, OH, the global capital of brand marketing, with additional offices in New York, Chicago, Los Angeles, and San Francisco.

GenomOncology

Venture Round in 2014
GenomOncology, LLC is a Cleveland-based genomics technology and services company dedicated to enhancing precision medicine by converting next-generation sequencing (NGS) data into actionable insights for clinicians and researchers. The company offers the GO Clinical Workbench, a decision support tool that translates raw sequencing data into detailed clinical reports based on the molecular profile of each patient's tumor genome. Additionally, GenomOncology provides GenomAnalytics, a research platform facilitating rapid, near real-time genome analysis and exploration for new discoveries. IgniteIQ is another solution offered, which extracts clinically relevant data from various reports and converts it into discrete data elements. The company also supports assay validation, integration with laboratory information systems, and custom feature development. Established in 2012, GenomOncology aims to improve patient outcomes through advanced data interpretation in oncology.

Petbrosia

Venture Round in 2014
Petbrosia, Inc. is a Cincinnati-based company that specializes in providing custom dog and cat food designed to meet the unique nutritional needs of individual pets. Founded in 2012, the company offers a range of grain-free options, including salmon and chicken, along with fruits and vegetables. Petbrosia utilizes an innovative e-commerce platform combined with a manufacturing and logistics system to deliver tailored pet food that supports the ideal body condition of pets. The company's mission is to enhance the wellbeing of dogs, cats, and their owners by offering products that cater to the specific dietary requirements of pets.

NanoVision Diagnostics

Seed Round in 2014
NanoVision Diagnostics, Inc. specializes in the development and commercialization of optical biomarkers for early cancer detection. The company has created a novel electro-optical diagnostic system that performs an optical analysis of standard biopsy slides. This analysis identifies molecular changes in nuclear structure that are not detectable through traditional pathology methods. By enabling medical practitioners to recognize these changes, NanoVision Diagnostics aims to facilitate the early detection and treatment of cancer, ultimately improving patient outcomes. Founded in 2013, the company is headquartered in Kittanning, Pennsylvania.

7SIGNAL

Series A in 2013
7SIGNAL® is a leader in enterprise wireless experience monitoring. 7SIGNAL provides a cloud-based platform that continuously monitors wireless networks and identifies elusive performance issues impacting application performance. By taking the “outside-in” approach to monitoring 7SIGNAL has visibility into the edge of any enterprise or home Wi-Fi network where complex device interaction exists, and user experience matters most. The platform maximizes employee productivity, operational efficiency and network ROI. Designed for the world’s most innovative organizations, educational institutions, healthcare systems and government agencies, the platform is currently deployed at Fortune 500 companies, hospitals and large venues globally. Learn more at www.7signal.com.

nChannel

Series A in 2013
nChannel, Inc. operates a Software-as-a-Service based multichannel management software for merchants. The company’s software enables merchants to sell any product in any channel, online or offline, by providing a single, cloud-based platform that integrates with existing systems to help sellers improve the management of product information, streamline supply chain processes, and enhance the overall shopping experience for customers. It offers solutions for product information management, multichannel listing, inventory synchronization, multichannel order management, drop ship management, supply chain management, vendor managed inventory, accounting integration, marketplace integration, and customer experience management. In addition, the company’s platform provides solutions for eCommerce, POS, ERP, and supply chain integration. It serves merchants of various sizes, as well as outdoor and sporting goods, consumer goods, apparel, gift and novelty, non-profit, and home industries. The company was founded in 2011 and is based in Columbus, Ohio.

SoMoLend

Seed Round in 2013
SoMoLend Holdings LLC operates a web-based platform that connects lenders and borrowers for financial solutions in the United States, primarily targeting small businesses and startups. Founded in 2011 and based in Cincinnati, Ohio, SoMoLend allows businesses to secure loans from a variety of sources, including banks, corporations, and local community members. The platform promotes peer-to-peer lending, enabling borrowers to raise funds from friends, family, and local investors. It serves as a transparent portal where lenders can assess potential borrowers in their communities, fostering local investment and support. The company's mission is to assist small businesses that struggle to obtain traditional funding, ultimately helping entrepreneurs grow and contributing to job creation and community development. SoMoLend's innovative approach to lending emphasizes the importance of community engagement and collaboration in financing local enterprises.

Ahalogy

Seed Round in 2013
Ahalogy is the Passion to Purchase Platform™. Brands and agencies tap into Ahalogy to grow users and use occasions by connecting with their consumers’ interests. We deliver proven ROI through our category trend data, authentic influencer content, and social optimization technology. Ahalogy is an official Pinterest Marketing Partner, and works with other leading social networks. Ahalogy is headquartered in Cincinnati, OH, the global capital of brand marketing, with additional offices in New York, Chicago, Los Angeles, and San Francisco.

DecisionDesk

Equity Crowdfunding in 2013
DecisionDesk is a recruitment, application, and enrollment management solution for Higher Education Institutions. DecisionDesk manages the admissions process, from prospect to decision. DecisionDesk saves institutions time and money with its next-generation admissions and enrollment platform. DecisionDesk's cloud-based solution includes complete supplemental materials management, online routing and review, video profiles, reporting, and CRM/SIS integration.

SparkBase

Series A in 2013
SparkBase is a gift card and loyalty platform that allows businesses to recognize and reward customers where ever and whenever they engage with their brand The company's real-time, API-driven loyalty engine uniquely positions SparkBase to integrate with the payment and marketing tools businesses already use to interact with customers, including: payment gateways, POS systems, e-commerce shopping carts, CRMs, email service providers, marketing databases and social media outlets. SparkBase is currently integrated with more than 40 POS systems, multiple payment gateways, and ExactTarget, one of the leading email providers. SparkBase combines best-in-class, proprietary technology with nearly a decade of experience in the loyalty industry. Thousands of businesses in the US and internationally trust SparkBase to power their gift cards and loyalty program and more than 100 resellers choose SparkBase as their preferred loyalty provider.

CardioX

Venture Round in 2013
CardioX is a company that specializes in developing advanced systems for measuring and monitoring various cardiovascular health parameters, including cardiac output, total circulating blood volume, and endogenous blood ammonia levels. Founded in 1996 and based in Columbus, Ohio, CardioX has expanded its offerings to include a mobile application for tracking and recording electrocardiograms (ECG). This app leverages a vast dataset from clinical records to enhance its machine learning algorithms, enabling the detection of abnormalities in cardiac patterns. Notably, CardioX has achieved a breakthrough in real-time blood pressure monitoring, providing users with accurate on-the-fly readings. The company is actively working on integrating data from third-party activity trackers and enhancing its artificial intelligence capabilities, which will allow users to interpret ECG graphs through simple image uploads. CardioX aims to harness these advancements to improve heart health management and expand the range of vital health parameters that can be monitored through its technology.

Cryothermic Systems, Inc.

Venture Round in 2012
Cryothermic Systems (formerly Life Core Technologies) is an American medical device firm that develops a series of products to improve patient outcomes by preventing brain damage. Its product Excel Cryo is a device that lowers the temperature of the brain, which can be applied immediately at the onset of neurologic injury. Cryothermic Systems was founded in 2008 and is based in Cleveland, Ohio.

Cryothermic Systems, Inc.

Series A in 2012
Cryothermic Systems (formerly Life Core Technologies) is an American medical device firm that develops a series of products to improve patient outcomes by preventing brain damage. Its product Excel Cryo is a device that lowers the temperature of the brain, which can be applied immediately at the onset of neurologic injury. Cryothermic Systems was founded in 2008 and is based in Cleveland, Ohio.

SoMoLend

Seed Round in 2012
SoMoLend Holdings LLC operates a web-based platform that connects lenders and borrowers for financial solutions in the United States, primarily targeting small businesses and startups. Founded in 2011 and based in Cincinnati, Ohio, SoMoLend allows businesses to secure loans from a variety of sources, including banks, corporations, and local community members. The platform promotes peer-to-peer lending, enabling borrowers to raise funds from friends, family, and local investors. It serves as a transparent portal where lenders can assess potential borrowers in their communities, fostering local investment and support. The company's mission is to assist small businesses that struggle to obtain traditional funding, ultimately helping entrepreneurs grow and contributing to job creation and community development. SoMoLend's innovative approach to lending emphasizes the importance of community engagement and collaboration in financing local enterprises.

Neuros Medical

Series B in 2012
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies to address unmet medical needs for patients globally. The company’s flagship technology, Electrical Nerve Block, targets the elimination of chronic pain associated with various conditions, including neuroma, residual limb pain, chronic post-surgical pain, and chronic migraines. Additionally, Neuros Medical offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices designed to enhance treatment outcomes. Founded in 2008, the company aims to provide innovative solutions for chronic pain management.

Juventas Therapeutics

Series B in 2012
Juventas Therapeutics, Inc., a clinical stage biotechnology company, develops non-viral gene therapies that activate natural processes to repair the body. The company focuses on treatment of non-healing wounds in patients with advanced peripheral artery disease. It offers JVS-100, a non-viral gene therapy that expresses stromal cell-derived factor-1 or SDF-1, a naturally occurring signaling protein that has been shown to recruit the body’s own stem cells and promote tissue repair in a range of disease states. Juventas Therapeutics, Inc. was formerly known as AcelleRX Therapeutics, Inc. and changed its name to Juventas Therapeutics, Inc. in April 2009. The company was founded in 2007 and is based in Cleveland, Ohio.

GenomOncology

Seed Round in 2012
GenomOncology, LLC is a Cleveland-based genomics technology and services company dedicated to enhancing precision medicine by converting next-generation sequencing (NGS) data into actionable insights for clinicians and researchers. The company offers the GO Clinical Workbench, a decision support tool that translates raw sequencing data into detailed clinical reports based on the molecular profile of each patient's tumor genome. Additionally, GenomOncology provides GenomAnalytics, a research platform facilitating rapid, near real-time genome analysis and exploration for new discoveries. IgniteIQ is another solution offered, which extracts clinically relevant data from various reports and converts it into discrete data elements. The company also supports assay validation, integration with laboratory information systems, and custom feature development. Established in 2012, GenomOncology aims to improve patient outcomes through advanced data interpretation in oncology.
Intelligent Mobile Support provides innovative technology solutions to help you support your sales reps and technicians in the field.

Neuros Medical

Series A in 2011
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies to address unmet medical needs for patients globally. The company’s flagship technology, Electrical Nerve Block, targets the elimination of chronic pain associated with various conditions, including neuroma, residual limb pain, chronic post-surgical pain, and chronic migraines. Additionally, Neuros Medical offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices designed to enhance treatment outcomes. Founded in 2008, the company aims to provide innovative solutions for chronic pain management.

SoMoLend

Seed Round in 2011
SoMoLend Holdings LLC operates a web-based platform that connects lenders and borrowers for financial solutions in the United States, primarily targeting small businesses and startups. Founded in 2011 and based in Cincinnati, Ohio, SoMoLend allows businesses to secure loans from a variety of sources, including banks, corporations, and local community members. The platform promotes peer-to-peer lending, enabling borrowers to raise funds from friends, family, and local investors. It serves as a transparent portal where lenders can assess potential borrowers in their communities, fostering local investment and support. The company's mission is to assist small businesses that struggle to obtain traditional funding, ultimately helping entrepreneurs grow and contributing to job creation and community development. SoMoLend's innovative approach to lending emphasizes the importance of community engagement and collaboration in financing local enterprises.

SironRX Therapeutics

Series A in 2011
SironRX is developing novel therapies exclusively licensed from Juventas Therapeutics and Cleveland Clinic that promote dermal wound repair and reduce scarring. Our lead product is a clinically tested biopharmaceutical that encodes Stromal cell-Derived Factor-1 (SDF-1). SDF-1 is key molecule responsible for activating natural repair processes after tissue injury through prevention of cell death and recruitment of stem cells to the damaged organ. Studies from several laboratories suggest the therapeutic potential of SDF-1 for treatment of a range of wounds such as post-surgical incisions, chronic diabetic ulcers and burns. Development of a cost-effective interactive wound therapy that can be topically administered at the site-of-injury or in chronic wound care settings with the potential to significantly improve function of the damaged tissue will have a major impact on the multi-billion dollar advanced wound management market.

SparkBase

Series A in 2011
SparkBase is a gift card and loyalty platform that allows businesses to recognize and reward customers where ever and whenever they engage with their brand The company's real-time, API-driven loyalty engine uniquely positions SparkBase to integrate with the payment and marketing tools businesses already use to interact with customers, including: payment gateways, POS systems, e-commerce shopping carts, CRMs, email service providers, marketing databases and social media outlets. SparkBase is currently integrated with more than 40 POS systems, multiple payment gateways, and ExactTarget, one of the leading email providers. SparkBase combines best-in-class, proprietary technology with nearly a decade of experience in the loyalty industry. Thousands of businesses in the US and internationally trust SparkBase to power their gift cards and loyalty program and more than 100 resellers choose SparkBase as their preferred loyalty provider.

EndoSphere

Series A in 2011
Endosphere is a developer of the novel endo-metabolic device category that provides non-invasive endoscopic therapies for gastrointestinal (GI) disorders and metabolic diseases including obesity, non-alcoholic fatty liver disease, type 2 diabetes, and drug delivery. It treats obesity using the body's natural physiology that enables patients to safely and effectively lose weight without the need for surgery or medications. Endosphere was founded in 2006 and is headquartered in Columbus, Ohio.

Assurerx Health

Series A in 2011
Assurex Health is a personalized medicine company dedicated to helping clinicians determine the right medication for individual patients with medical conditions. Assurex Health’s proprietary Genesight® technology is based on pharmacogenomics – the study of the genetic factors that influence an individual’s response to drug treatments – as well as evidence-based medicine and clinical pharmacology.

MAR Systems

Angel Round in 2011
MAR Systems was founded in 2006 to develop a patented, proprietary process to remove mercury, selenium, arsenic, and other metal contaminants from water. Headquartered in Cleveland, Ohio, MAR Systems’ Sorbster media technology assists companies in achieving the most strict EPA standards by chemisorbing contaminants and creating a non-hazardous disposal option. MAR Systems’ process has been co-developed with the EPA and is quickly becoming an industry standard. The company was founded in 2006 and is based in Cleveland, Ohio.

OnShift

Series A in 2010
OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare. Our suite of products for hiring, scheduling and employee engagement drives quality care, lower costs and higher performance by empowering providers to staff consistently and efficiently. Intuitive design, predictive analytics and customer success management are why thousands of post-acute care and senior living organizations rely on OnShift.

Theravasc

Series A in 2010
TheraVasc Inc. is a pharmaceutical company based in Cleveland, Ohio, specializing in the development of drugs for chronic medical conditions. Established in 2009, the company focuses on repurposing drugs to address unmet needs in the vascular disease market. Its primary product, TV1001, is an oral formulation of sodium nitrite designed to treat peripheral arterial disease and diabetic neuropathy, particularly targeting individuals with poor blood flow to their extremities. TheraVasc aims to provide effective treatment options that promote wound healing and prevent tissue necrosis in both humans and animals suffering from these conditions.
Prevacept Infection Control is a clinical-stage company focused on developing and commercializing products that prevent infections associated with indwelling catheters.

DecisionDesk

Seed Round in 2010
DecisionDesk is a recruitment, application, and enrollment management solution for Higher Education Institutions. DecisionDesk manages the admissions process, from prospect to decision. DecisionDesk saves institutions time and money with its next-generation admissions and enrollment platform. DecisionDesk's cloud-based solution includes complete supplemental materials management, online routing and review, video profiles, reporting, and CRM/SIS integration.

ABSMaterials

Series A in 2010
ABS Materials designs, develops, and delivers solutions for ground, surface, and municipal water contamination. Its solutions include VoC-Eater system, which destroys pharmaceuticals, chlorinated solvents, herbicides, endocrine disruptors, PCBs, dyes, and phenols to outflow clean water; Osorb, a solution to destroy persistent organic pollutants in the groundwater; and Iron-Osorb, an inert sand-like glass used on TCE/PCE/DCE/PCBs. The company’s solutions are used to clean solvents, pesticides, and other persistent organic pollutants from the water, soil, and air. It offers its systems on a rental and long term lease basis. The company was founded in 2008 and is based in Wooster, Ohio with an additional office in Houston, Texas.

i2c Technologies

Series A in 2009
i2c Technologies, LLC specializes in the development, integration, installation, and support of IP video surveillance and security solutions. Founded in 2005 and headquartered in Uniontown, Ohio, the company offers a range of products including fixed position megapixel cameras, camera controls, and recording and archiving systems. Additionally, i2c Technologies provides automated video alerts, network video surveillance, and access control solutions. Their technology platform features integrated camera and security hardware, along with a proprietary video management software (VMS) that allows clients to manage and control an extensive number of cameras through a centralized system.

Minimally invasive devices

Venture Round in 2009
MID has developed the FloShield system, a franchise of products that substantially improve visualization during laparoscopic surgery. During laparoscopic surgery, it is common for condensation to form on the end of the laparoscope obscuring vision. It is also common for debris from the ultrasonic scalpel, cautery, or even blood products themselves to degrade the surgical view. Most commonly, surgeons will need to remove the laparoscope for manual cleaning. It was founded in 2006 and headquartered in Columbus, Ohio.

Transactiv

Series A in 2009
Transactiv, Inc. is a Cincinnati-based company that provides on-demand commerce solutions tailored for mid-market businesses. Its key offerings include PartnerFront and StoreFront, which facilitate interactions between companies and their partners, suppliers, affiliates, and customers. Founded by a team with experience from industry leaders such as SAP, Microsoft, and i2, Transactiv aims to improve online commerce by effectively connecting a vast array of products and businesses. In addition to its headquarters in Cincinnati, the company has another office in Boulder, Colorado. Formerly known as Envolve Commerce, Transactiv is committed to meeting the evolving needs of businesses in the digital marketplace.

Neuros Medical

Venture Round in 2009
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies to address unmet medical needs for patients globally. The company’s flagship technology, Electrical Nerve Block, targets the elimination of chronic pain associated with various conditions, including neuroma, residual limb pain, chronic post-surgical pain, and chronic migraines. Additionally, Neuros Medical offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices designed to enhance treatment outcomes. Founded in 2008, the company aims to provide innovative solutions for chronic pain management.

Brand Thunder

Venture Round in 2009
Brand Thunder, LLC builds custom browser themes for brand marketers. It has strategic partnerships with Coolfire Media, KAM Sports International, DMB Sports Group, Inc., and Adevia Software. The company was founded in 2007 and is based in Dublin, Ohio.

CardioX

Seed Round in 2008
CardioX is a company that specializes in developing advanced systems for measuring and monitoring various cardiovascular health parameters, including cardiac output, total circulating blood volume, and endogenous blood ammonia levels. Founded in 1996 and based in Columbus, Ohio, CardioX has expanded its offerings to include a mobile application for tracking and recording electrocardiograms (ECG). This app leverages a vast dataset from clinical records to enhance its machine learning algorithms, enabling the detection of abnormalities in cardiac patterns. Notably, CardioX has achieved a breakthrough in real-time blood pressure monitoring, providing users with accurate on-the-fly readings. The company is actively working on integrating data from third-party activity trackers and enhancing its artificial intelligence capabilities, which will allow users to interpret ECG graphs through simple image uploads. CardioX aims to harness these advancements to improve heart health management and expand the range of vital health parameters that can be monitored through its technology.

Znode

Series A in 2008
Znode LLC, an e-commerce software company, provides .NET e-commerce software solutions. The company offers multi-store e-commerce platform solutions that allow users to build various multi-brand websites using a single shared database; and multi-tenancy e-commerce platform solutions to launch multi-tenant e-commerce stores. It also offers training and consulting, technical support, and professional services. The company serves manufacturers, distributors, and retailers worldwide. Znode LLC was founded in 2001 and is headquartered in Milwaukee, Wisconsin with a development center in India. As of December 31, 2014, Znode LLC operates as a subsidiary of MRR Soft Inc.

Cervilenz

Seed Round in 2008
CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

Zebra Ventures

Post in 2008
Zebra Ventures is the strategic investment arm of Zebra Technologies, focusing on early-stage companies that align with the vision of Enterprise Asset Intelligence. The firm seeks partnerships that enhance productivity and improve customer experiences across various sectors, including retail, transportation, logistics, warehousing, manufacturing, and healthcare. Zebra Ventures combines the rigor of a financial investor with the advantages of a strategic partner, offering venture capital to support companies through their startup, growth, and expansion phases. In addition to financial support, it leverages its deep industry expertise, engineering resources, and extensive distribution network to aid portfolio companies in achieving their growth objectives.

3X Systems

Series A in 2008
3X Systems competes in the offsite data backup market with its proprietary Remote Backup Appliance (RBA). The 3X RBA delivers technology similar to an online backup provider in an appliance that can be purchased and deployed by an end user or IT Provider. The product is currently being sold to: - Small and Mid-Sized businesses as a complete, offsite backup solution, - Enterprises as a backup solution for remote offices and traveling laptops, and - IT Providers as the infrastructure for backup services The product includes advanced data deduplication technology, a remote management console, and a proprietary Locator Service that permits the appliance to be moved from site to site, or stored in a non-static IP environment, without the need to reconfigure endpoints.

Stanton Advanced Ceramics

Angel Round in 2007
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.

Exacter

Series A in 2007
Exacter, Inc. specializes in outage-avoidance technology and services tailored for the electric utility sector. The company has developed EXACTER, a system designed to alert utilities to potential failures in critical components such as transformers, regulators, insulators, cutouts, and lightning arrestors. In addition to its core technology, Exacter offers services that include program deployment design, distribution overhead surveys, and the identification and reporting of failing components. Founded in 2006 and headquartered in Columbus, Ohio, Exacter has established strategic partnerships to enhance its service offerings and industry reach.

Nine Iron Innovations

Angel Round in 2007
Nine Iron Innovations provides automated mobile video monitoring systems for golf course contests and events. The company’s product portfolio includes VerishotMobile, a golf shot video monitoring, contest, and marketing program for golf courses, event managers, golf management organizations, and independent representatives; and Sharegolf.com, a social networking site that connects golf courses and golfers, and allows them to view and share videos of their swings with other members. Nine Iron Innovations was founded in 2004 and is based in Ohio, United States.