North East Fund

Nanovery Limited, founded in 2018 and based in London, United Kingdom, specializes in developing nanorobots aimed at detecting cancer mutations. The company's innovative platform utilizes artificial intelligence to facilitate the rapid and ultra-sensitive identification of challenging biomarkers in blood samples. These nanorobots can capture circulating tumor DNA and emit a fluorescent signal, enabling healthcare professionals to conduct point-of-care tests. By facilitating early cancer detection, Nanovery aims to enhance patient outcomes and increase survival rates. The organization is supported by a team of experts in nanotechnology, medicinal chemistry, and artificial intelligence, along with backing from leading academics, clinicians, and industry leaders.

Aelius Biotech specializes in creating advanced models of the mucosal surfaces of the human body. The company focuses on developing systems that simulate the gastrointestinal tract and airways, with ongoing efforts to model the eye and cervico-vaginal tract. Aelius Biotech's model gut system allows healthcare industry participants to simulate essential processes such as digestion, mucus permeation, and epithelial absorption. The company provides a range of testing services, including in vitro and in vivo assessments, simple lab assays, and integrated model gut testing across the aerodigestive tract. Additionally, Aelius Biotech conducts human trials, aiding healthcare companies in making informed, data-driven decisions to enhance and de-risk the development of orally delivered products.

Circadacare is a health technology company focused on enhancing the quality of life for older adults through innovative solutions in care environments. The company specializes in developing integrated systems that combine lighting, sensors, and software technology to synchronize the day-night cycle for residents, thereby improving their overall well-being. By translating scientific principles into practical applications, Circadacare aims to create care home lighting services that not only benefit the residents but also support staff efficiency. The solutions provided by Circadacare are designed to operate seamlessly, requiring minimal training for staff, while delivering both care outcome improvements for older adults and cost benefits for operators of nursing homes, care villages, and dementia care centers.

onHand is an on-demand volunteering platform designed to simplify the process of volunteering and connect individuals with local charitable opportunities. By matching verified volunteers with organizations in need of assistance, the platform allows users to search for and engage in micro-volunteering projects that have a significant impact in their communities. This approach makes volunteering as accessible as ordering a meal delivery, fostering a culture of social and environmental responsibility while providing a convenient way for people to contribute to local causes. Through its user-friendly interface, onHand aims to encourage more individuals to participate in volunteer work, thereby enhancing community engagement and support for various local initiatives.

Newcells Biotech Limited is a biotechnology company based in Newcastle upon Tyne, United Kingdom, specializing in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types. Founded in 2014, the company provides a selection of off-the-shelf iPSC-derived cell lines for research and development purposes. Their offerings include bespoke iPSCs derived from patient tissues, neural progenitor cells, cardiomyocytes for cardiac disease modeling, haematopoietic progenitor cells, and other somatic cell types tailored to user specifications. Additionally, Newcells Biotech supports drug discovery and pre-clinical development by developing in vitro cell-based assays that mimic the physiology of organs such as the kidney, retina, liver, and lung. This facilitates improved predictions of safety, pharmacology, and efficacy in drug testing, allowing researchers to evaluate new drug candidates effectively.

AMLo Biosciences Ltd is a company focused on developing diagnostic solutions for melanoma, specifically through its prognostic test, AMBLor. This test aims to accurately predict the risk of disease progression in patients diagnosed with early AJCC Stage I and Stage II melanoma. By identifying two specific proteins that are lost in high-risk melanomas, AMBLor helps to stratify patients for appropriate treatment and follow-up care. The company, incorporated in 2017 and based in Newcastle upon Tyne, United Kingdom, seeks to reduce the psychological burden on patients while also providing cost savings to health authorities by minimizing unnecessary patient surveillance.

FAT32 is a technology company specializing in compliance automation. It provides a platform that continuously monitors and assesses a business's infrastructure and tools to ensure they remain compliant with relevant regulations. The platform also automatically identifies and manages 'shadow IT' applications, and generates custom reports to help businesses meet regulatory demands efficiently.

NunaBio is a privately-owned DNA development company based in England, United Kingdom. The company specializes in creating a variety of chemical and biological technologies and products, including long and short deoxyribonucleic acid (DNA) products available in microgram to gram scales. NunaBio is involved in contract research and development, as well as manufacturing services, offering expertise in cell therapies, vaccines, diagnostics, and gene therapies. Additionally, the company focuses on advanced DNA biosensing and associated consumables, supporting healthcare professionals in their efforts to treat patients effectively.

PolyBox.app is a marketing tool designed to enhance the reporting processes of marketing agencies and teams through automation and AI technology. The platform enables users to consolidate data from various sources, facilitating real-time queries and analysis. By automating the generation of reports, PolyBox allows marketers to efficiently track campaign performance and optimize strategies, minimizing reliance on traditional spreadsheets and manual reporting methods. The service includes detailed visual dashboards that provide insightful overviews of campaign results, enabling teams to make informed decisions swiftly. Ultimately, PolyBox.app aims to improve the accuracy of reporting and save time for marketing professionals, helping them deliver superior results for their clients.

Microbritt specializes in micromachining technology that enables the fabrication of customer-defined products from various materials. The company employs a patented process that allows for the defect-free machining of brittle materials, facilitating rapid prototyping and enhancing the pace of innovation for its clients. By offering solutions that extend from wafer-scale applications to larger formats, Microbritt addresses the needs of industries requiring precise and reliable micromachining capabilities.

Dragonfly Insulation is a spin-out from Newcastle University focused on scaling up the production of aerogel materials through an innovative manufacturing process that emphasizes low energy consumption. The company specializes in creating synthetic nanostructured porous ceramic products designed to provide effective thermal insulation across various sectors, including aerospace, defense, marine, oil and gas, and construction. By simplifying the manufacturing process, Dragonfly Insulation aims to improve accessibility to advanced fire safety features in civil applications, catering to a diverse range of industry needs.

Newcells Biotech Limited is a biotechnology company based in Newcastle upon Tyne, United Kingdom, specializing in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types. Founded in 2014, the company provides a selection of off-the-shelf iPSC-derived cell lines for research and development purposes. Their offerings include bespoke iPSCs derived from patient tissues, neural progenitor cells, cardiomyocytes for cardiac disease modeling, haematopoietic progenitor cells, and other somatic cell types tailored to user specifications. Additionally, Newcells Biotech supports drug discovery and pre-clinical development by developing in vitro cell-based assays that mimic the physiology of organs such as the kidney, retina, liver, and lung. This facilitates improved predictions of safety, pharmacology, and efficacy in drug testing, allowing researchers to evaluate new drug candidates effectively.

Aelius Biotech specializes in creating advanced models of the mucosal surfaces of the human body. The company focuses on developing systems that simulate the gastrointestinal tract and airways, with ongoing efforts to model the eye and cervico-vaginal tract. Aelius Biotech's model gut system allows healthcare industry participants to simulate essential processes such as digestion, mucus permeation, and epithelial absorption. The company provides a range of testing services, including in vitro and in vivo assessments, simple lab assays, and integrated model gut testing across the aerodigestive tract. Additionally, Aelius Biotech conducts human trials, aiding healthcare companies in making informed, data-driven decisions to enhance and de-risk the development of orally delivered products.

Luminous Group Limited specializes in providing 3D digital technology solutions, focusing on digital surveying and imaging for the construction, architecture, and engineering sectors. Established in 1988 and based in Newcastle upon Tyne, the company offers a range of services, including 3D laser scanning, building information modeling (BIM) consultancy, and virtual reality experiences. Its expertise encompasses digital surveys, 3D modeling, offshore laser scanning, and point cloud processing. Luminous Group also develops and provides software to enhance its service offerings. With over 25 years of experience, the company serves clients in various industries, including architecture and heritage tourism, and was formerly known as Digital Surveys Limited before rebranding in 2016. Luminous Group operates as a subsidiary of Peterhouse Group Limited.

Manus Neurodynamica Ltd specializes in manufacturing medical diagnostic technologies aimed at identifying and monitoring neuromotor impairments, particularly focusing on Parkinson's disease. Founded in 2008 and based in North Shields, United Kingdom, the company has developed a triage device that supports early diagnostics for this condition. Its innovative technology integrates analytical software to assess a patient's movement parameters by examining subtle limb and hand motions. This capability allows clinicians to quantify fine motor skills and motion features, enhancing the diagnosis and ongoing monitoring of Parkinson's disease. Manus Neurodynamica's solutions are utilized across various sectors, including academic and pharmaceutical research, as well as non-medical applications, contributing to improved efficiency and reduced costs in specialist neuromotor services.

NunaBio is a privately-owned DNA development company based in England, United Kingdom. The company specializes in creating a variety of chemical and biological technologies and products, including long and short deoxyribonucleic acid (DNA) products available in microgram to gram scales. NunaBio is involved in contract research and development, as well as manufacturing services, offering expertise in cell therapies, vaccines, diagnostics, and gene therapies. Additionally, the company focuses on advanced DNA biosensing and associated consumables, supporting healthcare professionals in their efforts to treat patients effectively.

Nanovery Limited, founded in 2018 and based in London, United Kingdom, specializes in developing nanorobots aimed at detecting cancer mutations. The company's innovative platform utilizes artificial intelligence to facilitate the rapid and ultra-sensitive identification of challenging biomarkers in blood samples. These nanorobots can capture circulating tumor DNA and emit a fluorescent signal, enabling healthcare professionals to conduct point-of-care tests. By facilitating early cancer detection, Nanovery aims to enhance patient outcomes and increase survival rates. The organization is supported by a team of experts in nanotechnology, medicinal chemistry, and artificial intelligence, along with backing from leading academics, clinicians, and industry leaders.

MySalesCoach provides a sales coaching platform that connects sales coaches with teams seeking guidance and support. Recognizing that sales managers often spend minimal time on coaching, the platform addresses this gap by offering services that facilitate effective coaching for both individuals and teams. This technological support is designed to help sales representatives enhance their skills, accelerate their growth, and optimize sales performance. Ultimately, MySalesCoach aims to empower sales teams to reach their full potential through targeted coaching and development.

Footy.com is an online platform that specializes in price comparison for sportswear, primarily focused on football-related products. It operates a portal that allows users in the UK, Europe, and the USA to compare prices on a wide range of items, including football kits, boots, trainers, and training wear from various reputable brands and retailers. By providing access to thousands of products, Footy.com aims to make football merchandise more affordable and accessible for everyone, facilitating an easier online shopping experience for customers seeking the best deals.

Magnitude Biosciences Limited is a biotechnology company specializing in drug discovery solutions and services, particularly in the field of aging research. Founded in 2018 and based in Durham, United Kingdom, the company utilizes the nematode C. elegans in its research methodologies. Magnitude Biosciences has developed a healthspan machine that employs multiple small computers connected to cameras to monitor these organisms under various experimental conditions. This innovative approach assists academic researchers and the aging research industry in evaluating compounds, including food additives and pharmaceuticals. By providing tailored studies and tools, Magnitude Biosciences aims to enhance the quality of data generated in research areas such as neurodegeneration, toxicity, and microbiome studies, ultimately optimizing productivity for its clients in the drug discovery sector.

Newcells Biotech Limited is a biotechnology company based in Newcastle upon Tyne, United Kingdom, specializing in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types. Founded in 2014, the company provides a selection of off-the-shelf iPSC-derived cell lines for research and development purposes. Their offerings include bespoke iPSCs derived from patient tissues, neural progenitor cells, cardiomyocytes for cardiac disease modeling, haematopoietic progenitor cells, and other somatic cell types tailored to user specifications. Additionally, Newcells Biotech supports drug discovery and pre-clinical development by developing in vitro cell-based assays that mimic the physiology of organs such as the kidney, retina, liver, and lung. This facilitates improved predictions of safety, pharmacology, and efficacy in drug testing, allowing researchers to evaluate new drug candidates effectively.

CellRev is a biotechnology company specializing in innovative bioprocessing technologies aimed at improving cell manufacturing for various applications, including cultured meat, cell therapy, and biologics. The company's proprietary technology enables a shift from traditional batch processing to continuous processing of adherent cells, significantly enhancing yield while reducing operating costs and capital expenditures. CellRev's unique cell detachment process, combined with a specially designed bioprocess, addresses critical challenges in manufacturing, such as cell aggregation, clumping, and detachment. This approach allows cell-based vaccine and therapy developers to streamline their production processes, eliminate serum usage, and overcome significant bottlenecks in the industry.

Hicomply is a software platform that provides businesses with the tools necessary to develop and manage their information security management systems (ISMS) effectively. The platform offers a comprehensive solution for protecting business data and managing information security compliance. It features a customized interface that consolidates various aspects of information security management, allowing users to gain actionable insights. Hicomply includes a content-rich library of structured controls and risk information, which is aligned with relevant regulations, legislation, and industry standards. This enables organizations of all sizes to implement robust information security practices and enhance their overall data protection strategies.

Manus Neurodynamica Ltd specializes in manufacturing medical diagnostic technologies aimed at identifying and monitoring neuromotor impairments, particularly focusing on Parkinson's disease. Founded in 2008 and based in North Shields, United Kingdom, the company has developed a triage device that supports early diagnostics for this condition. Its innovative technology integrates analytical software to assess a patient's movement parameters by examining subtle limb and hand motions. This capability allows clinicians to quantify fine motor skills and motion features, enhancing the diagnosis and ongoing monitoring of Parkinson's disease. Manus Neurodynamica's solutions are utilized across various sectors, including academic and pharmaceutical research, as well as non-medical applications, contributing to improved efficiency and reduced costs in specialist neuromotor services.

BelleVie is a provider of personal care services aimed at supporting individuals in their daily lives while enabling them to maintain their independence. The company offers a range of services, including personal care, meal preparation, home assistance, social engagement, and specialized care. BelleVie operates with a unique model of self-managing teams, inspired by the successful Buurtzorg approach from the Netherlands, which emphasizes fulfilling careers in care and fosters meaningful relationships within the care ecosystem. The company utilizes its proprietary Wellbeing OS technology platform to facilitate its operations, funded through a monthly subscription model. BelleVie’s vision focuses on creating a society where every individual is valued and supported, ensuring that care providers and recipients alike benefit from reciprocal and enriching interactions.

Incuto Limited is a financial technology company based in Ilkley, United Kingdom, that specializes in developing SaaS-based banking software tailored for credit unions, community banks, and Community Development Financial Institutions (CDFIs). Established in 2016, Incuto provides the incuto Hive platform, which streamlines back-office processes, enhances financial education, and facilitates communication and performance management. This technology enables credit unions to offer a range of banking services, including debit cards and bank accounts, while competing effectively with high-cost lenders. The platform is accessible 24/7 on various devices, allowing for quick loan processing and providing crucial support to underserved populations, including those in rural areas. Incuto aims to empower credit unions to operate more efficiently and digitally, ultimately enhancing their service offerings and reducing operational costs.

Magnitude Biosciences Limited is a biotechnology company specializing in drug discovery solutions and services, particularly in the field of aging research. Founded in 2018 and based in Durham, United Kingdom, the company utilizes the nematode C. elegans in its research methodologies. Magnitude Biosciences has developed a healthspan machine that employs multiple small computers connected to cameras to monitor these organisms under various experimental conditions. This innovative approach assists academic researchers and the aging research industry in evaluating compounds, including food additives and pharmaceuticals. By providing tailored studies and tools, Magnitude Biosciences aims to enhance the quality of data generated in research areas such as neurodegeneration, toxicity, and microbiome studies, ultimately optimizing productivity for its clients in the drug discovery sector.