Amino is a healthcare financial wellness platform that helps companies and their employees navigate the complexities of the US healthcare system and find the highest value care, which has become even more important of late. It simplifies high-value healthcare benefits by providing data-driven, individualized care suggestions that plan members will follow. With a system that benefits patients and everyone, Amino Health makes healthcare more intuitive, accessible, and convenient.
Amino is a healthcare financial wellness platform that helps companies and their employees navigate the complexities of the US healthcare system and find the highest value care, which has become even more important of late. It simplifies high-value healthcare benefits by providing data-driven, individualized care suggestions that plan members will follow. With a system that benefits patients and everyone, Amino Health makes healthcare more intuitive, accessible, and convenient.
Antheia is a biotechnology company unlocking the medicinal power of nature with its rapid response biomanufacturing processes for essential medicines. Antheia uses synthetic biology to surpass the limits of conventional drug manufacturing and discovery. By reconstructing complex molecules in yeast, Antheia can produce APIs without the use of medicinal plants, transforming the pharmaceutical supply chain and ensuring reliable, consistent, and widespread availability to essential medicines.
SeLux Diagnostics is a developer of the next-generation phenotyping platform that provides personalized antimicrobial therapies to patients. The company is revolutionizing patient care by expediting the selection of personalized antimicrobial therapy for all infectious disease patients. This advancement will save lives, reduce hospital stays, and address the escalating antibiotic resistance epidemic by minimizing the overuse of broad-spectrum agents.
Silk Road Medical is a medical company that provides medical devices and solutions for treating vascular diseases. The company develops and manufactures less-invasive medical devices to improve the treatment of carotid artery disease through proprietary trans-carotid therapies.
Verastem Oncology is a late-stage development biopharmaceutical company committed to the development and commercialization of new medicines to improve the lives of patients diagnosed with RAS/MAPK pathway-driven cancers. Our pipeline is focused on novel small molecule drugs that inhibit critical signaling pathways in cancer that promote cancer cell survival and tumor growth, including RAF/MEK inhibition, FAK inhibition, and KRAS G12D inhibition.
Lexicon Pharmaceuticals is a biopharmaceutical company engaged in the discovery and development of pharmaceutical products for the treatment of human diseases, including those in the fields of immunology, metabolism, cardiology, and ophthalmology. The company's drug candidates include LX1031, which has completed Phase II clinical trials for the treatment of irritable bowel syndrome and other gastrointestinal disorders; LX4211, which has completed Phase II clinical trials for the treatment of type 2 diabetes; LX2931, which is in Phase II clinical trials for the treatment of rheumatoid arthritis and other autoimmune diseases; and LX1032, which has completed Phase II clinical trials for the treatment of symptoms associated with carcinoid syndrome. Additionally, the company is developing a preclinical drug candidate, LX7101, for the treatment of glaucoma. Lexicon Pharmaceuticals has established drug discovery alliances with Bristol-Myers Squibb Company, Genentech, Inc., N.V. Organon, and Takeda Pharmaceutical Company Limited. It also has a drug development financing collaboration with Symphony Icon, a collaboration agreement with Taconic Farms, Inc., and an alliance with Nuevolution A/S for access to Nuevolution's Chemetics platform chemistry technology.
CENTOGENE is one of the largest genetic biotech companies worldwide, the European market leader, and one of the global leaders in genetic diagnostic analyses of rare inherited diseases. Transforming global genetic data into medical decisions, that are focused on creating broarder awareness for patients of all ethnicities around the world. CENTOGENE is a rare disease company focused on transforming clinical, genetic, and biochemical data into medical solutions for Patients. With headquarters in Rostock, Germany and further operations in Berlin, Germany as well as Cambridge, Massachusetts, USA, CENTOGENE is dedicated to transforming the science of genetic information into solutions and hope for patients with rare diseases and their families. CENTOGENE provides the full spectrum of modern methods and technology for human genetics analysis; it is active in research and is constantly developing new and innovative products for human genetics.
Sierra Oncology is a late-stage biopharmaceutical company on a mission to deliver targeted therapies that treat rare forms of cancer. The company harnesses its deep scientific expertise to identify compounds that target the root cause of disease. Sierra Oncology's team takes an evidence-based approach to understand the limitations of current treatments and explore new ways to change the cancer treatment paradigm. Sierra Oncology is transforming promise into patient impact.
Choice Health at Home is comprehensive home health, hospice, and rehabilitation service company.
Kezar Life Sciences company focused on the discovery and development of drugs targeting protein homeostasis for autoimmune disorders. In parallel with this work, Christopher and Kezar co-founder Jack Taunton, Ph.D. collaborated on several research projects involving protein secretion. This collaboration inspired a belief in the strong synergies between protein degradation and protein secretion, two fertile areas for drug discovery with platform potential.
Viracta is a precision oncology company targeting virus-associated malignancies. Viracta's proprietary investigational drug, nanatinostat, is currently being evaluated in combination with the antiviral agent valganciclovir as an oral combination therapy in a Phase 2 clinical trial for EBV-positive lymphoma. Viracta is pursuing application of this inducible synthetic lethality approach in other EBV-associated malignancies, such as nasopharyngeal carcinoma, gastric carcinoma, and other virus-related cancers.
Platelet BioGenesis specializes in the fields of biotechnology, platelets, and drug discovery. They discover a new category in therapeutics. The company is developing technology to produce donor-independent human platelets from human induced pluripotent stem cells.
Impel Pharmaceuticals is a late-stage pharmaceutical company focused on utilizing its proprietary technology to develop and commercialize transformative therapies for people suffering from diseases with high unmet needs, with an initial focus on diseases of the CNS. The Company’s strategy is to rapidly advance its product candidate pipeline that pairs its proprietary Precision Olfactory Delivery (POD) system with well-established therapeutics, including TRUDHESA™ for the acute treatment of migraine, INP105 for the acute treatment of agitation and aggression in patients with autism, and INP107 for OFF episodes in Parkinson’s disease.
Kala Pharmaceuticals is developing novel treatments for diseases that affect mucosal tissues. The company's proprietary mucus penetrating particle technology dramatically improves drug distribution and pharmacokinetics by uniformly coating the mucosal surface with biocompatible, drug-loaded particles. Kala's formulations achieve high, sustained local drug concentrations with reduced systemic exposure and are delivered in a patient-friendly format. The company's research efforts have demonstrated successful in vivo proof-of-concept in mucosal organs such as the respiratory tract, eye, and cervicovaginal tract, enabling diverse product opportunities that target significant clinical unmet need. Kala is focused on advancing an internal pipeline of products through human proof-of-concept while establishing R&D collaborations with select partners to improve products in their pipelines.
Mainstay Medical is a global medical device company headquartered in Dublin, Ireland and with operations in the United States and Australia. They are partnering with scientists and clinical experts to deliver innovative therapies for the large underserved population of people with debilitating chronic low back pain.
Immunocore is focused on the discovery and development of novel T cell receptor-based drugs to treat diseases with a high unmet need, including cancer and viral disease. The company’s expertise in engineering T Cell Receptors (TCRs) and linking them to an antibody fragment (scFv) known as anti-CD3, has led to its first product candidate, IMCgp100, entering clinical trials in patients with metastatic melanoma. The proprietary T Cell Receptor technology platform is well validated and can easily be manufactured for clinical and commercial supply in microbial systems. Immunocore is a biotechnology company that specializes in the development of TCR bispecific immunotherapies.
Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.
Nature’s Fynd is a food company producing a protein from a microbe discovered in the geothermal springs. The company's mission is to create foods that both nourish people and the planet. Its revolutionary fermentation technology grows protein using a fraction of the land and water resources required by traditional agriculture. Nature’s Fynd was founded in 2012 and is headquartered in Chicago, Illinois.
RxSight, Inc. is a commercial-stage medical technology company dedicated to improving the vision of patients following cataract surgery. The RxSight Light Adjustable Lens system, comprised of the RxSight Light Adjustable Lens (LAL®), RxSight Light Delivery Device (LDD) and accessories, is the first and only commercially available intraocular lens (IOL) technology that enables doctors to customize and optimize visual acuity for patients after cataract surgery. The LAL now features ActivShield™ technology, a revolutionary UV protection layer built into the lens.
Scholar Rock is a biopharmaceutical company focused on the discovery and development of innovative medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role. The company's newly elucidated understanding of the molecular mechanisms of growth factor activation enabled us to develop a proprietary platform for the discovery and development of monoclonal antibodies that locally and selectively target these signaling proteins at the cellular level. They believe this approach, acting in the disease microenvironment, avoids the historical challenges associated with inhibiting growth factors for therapeutic effect. We believe our focus on biologically validated growth factors may facilitate a more efficient development path. The company is advancing its lead product candidate, SRK-015, a selective first-in-class inhibitor of the activation of the growth factor myostatin in skeletal muscle, into clinical development for the treatment of spinal muscular atrophy, or SMA. They expect to initiate a Phase 1 clinical trial in the second quarter of 2018. Utilizing its proprietary platform, they are also creating a pipeline of novel product candidates with the potential to transform the lives of patients suffering from a wide range of serious diseases, including other neuromuscular disorders, cancer, fibrosis, and anemia.
SpendMend is a healthcare organization nationwide discovers the full impact of financial leakage upon their organization.
ReMed provides rehabilitation services, neurobehavioral services, and supported living for people with mild, moderate, and severe brain injuries. They offer residential, outpatient, and home and community-based treatment.
Vedanta Biosciences is a developer of immunotherapies designed to treat immune-mediated and infectious diseases. It includes a suite of proprietary assays to select pharmacologically potent strains, vast proprietary datasets from human interventional studies, and facilities for cGMP-compliant manufacturing of rationally defined bacterial consortia in powder form to help physicians have access to live bacteria drugs to treat autoimmune and inflammatory diseases easily.
Enable Injections designs, manufactures, and sells wearable delivery devices for injectable drugs. The Enable Injections products can deliver drugs directly from standard vials supplied by all pharmaceutical companies, can reconstitute powdered drugs into liquids as a part of the injection procedure, can inject very viscous drugs, and can inject up to 20 ml. Such products are called bolus injection systems. No other existing drug delivery device can accomplish all of these tasks. For inquiries, telephone and contact numbers are used. Approximately 900 new drugs are being developed that may require bolus injection technology like that being developed by Enable Injections. The total market is expected to reach $8 billion within ten years. Partisan principals have supplied 10% of the seed capital to Enable Injections. It also delivers a controlled flow of up to 50 ml of a biologic through an automatically inserted needle. Enable Injections also offers a version of the drug delivery platform that may connect to smartphones via Bluetooth. It also utilizes any standard container closure system, including syringes or vials; automatically warms and can automatically mix lyophilized solutions. Enable Injections was founded in 2010 and is headquartered in Cincinnati, Ohio, USA.
Selecta Biosciences is a biopharmaceutical company developing the first generation of nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. Their proprietary product platform technology combines recent advances in immunobiology with cutting-edge nanotechnology to develop targeted immunomodulatory nanoparticles. It was founded in 2008 and is headquartered in Watertown, Massachusetts.
Epic Healthcare Staffing is a diversified national provider of staffing services to the healthcare and bio-pharmaceutical industries.
Syros Pharmaceuticals is a life sciences company that is focused on treating disease by mapping gene regulatory circuits and modulating the factors that regulate gene expression. Syros has pioneered world-leading gene control research and drug discovery capabilities with a proven ability to integrate disease biology and genomic data--a proficiency that is not well represented in pharmaceutical R&D. Central to the Syros approach is a proprietary platform of carefully integrated assay technologies, bioinformatics, and biologic insights developed by members of Syros' senior leadership. While this scientific approach has applications in many therapeutic areas, Syros has demonstrated success initially in oncology, where it may help address numerous unmet medical needs.
Our mission is to transform research and diagnostics with an affordable, scalable genomic sequencing ecosystem. We believe in providing innovative sequencing solutions and high-quality service to our customers and partners. We lead with integrity and resiliency. We promise our stakeholders transparency, inclusivity and collaboration. It was founded in 2010 and headquartered in Redwood City, California.
Equillium Inc is a biotechnology company that develops products for autoimmune and inflammatory, or immuno-inflammatory disorders with an unmet medical need. Its primary product candidate is EQ001, which is a clinical-stage first-in-class monoclonal antibody that selectively targets the novel immune checkpoint receptor CD6. CD6 plays a central role in effector T cell activity, which drives a number of immuno-inflammatory diseases such as graft versus host disease, asthma, uveitis, colitis, lupus, and multiple sclerosis.
LogicBio develops gene therapy vectors for previously incurable genetic and infectious diseases. It is committed to delivering genetic medicine to pediatric patients with rare diseases. Their proprietary technology based on the non-pathogenic adeno-associated viral vector offers superior efficiency and safety compared to all competitors on the market and is uniquely suited for the treatment of children as well as adults.
Xeris Biopharma is a specialty pharmaceutical company leveraging its novel formulation technology platforms to develop and commercialize ready-to-use, liquid-stable injectables. The company’s proprietary XeriSol and XeriJect formulation technologies allow for the subcutaneous (SC) and intramuscular (IM) delivery of highly concentrated, non-aqueous, ready-to-use formulations of peptides, proteins, antibodies, and small molecules using syringes, auto-injectors, multi-dose pens, and infusion pumps. Xeris’ platforms have the potential to offer distinct advantages over existing formulations of marketed and development-stage products. In particular, XeriSol and XeriJect offer the opportunity to eliminate reconstitution, enable long-term room temperature stability, significantly reduce injection volume, and eliminate the requirement for intravenous (IV) infusion. These attributes can lead to products that are easier to use by patients, caregivers, and health practitioners and reduce costs for payers and the healthcare system.
Codex DNA is a biology company helping researchers with the tools they need to securely design, code, and create synthetic DNA. The company is on a mission to help scientific researchers in both academic and commercial settings with the hardware, software, materials, and methodologies required to rapidly and accurately write large quantities of synthetic genes. To, in effect, build biology. Its gene synthesis portfolio reduces the turnaround time for synthesizing workflows from weeks and months to days and hours and includes the BioXp system, DNA services, Gibson Assembly reagents, and Vmax chemically competent cells. In addition to automating, speeding, and optimizing DNA design and synthesis, Codex DNA and the BioXp system ensure your designs stay in your hands, marrying speed and security for innovators in drug discovery, vaccine development, precision medicine, and beyond. Co-founded by Dan Gibson — the creator of the industry-standard Gibson Assembly methodology — Codex DNA is attempting nothing less than changing everything.
MolecuLight provides innovative imaging solutions for wound care, focusing on the detection of harmful bacteria and accurate wound measurement. The company’s devices facilitate effortless documentation and monitoring of wound healing progress.
ObsEva SA is a Swiss-based, speciality biopharmaceutical company dedicated to the development of innovative drugs for women's reproductive medicine. ObsEva's main focus is on therapies for preterm labor. ObsEva was founded in November 2012, by Ernest Loumaye MD, PhD and André Chollet PhD. Ernest Loumaye is a specialist in female reproductive medicine with 20 years of experience in the biopharmaceutical industry. Ernest Loumaye was previously Co-Founder and CEO of PregLem SA, a successful biopharmaceutical company which was acquired by Gedeon Richter in 2010. André Chollet is specialist in medicinal and pharmaceutical chemistry with more than 30 years of experience in diverse positions in the biopharmaceutical industry, including in Biogen, GSK and Merck Serono. André Chollet was responsible for the preterm labor program at Serono before the acquisition of the company by Merck KGaA.
Talphera is a specialty pharmaceutical company developing and commercializing therapies in medically supervised settings. It offers NanoTab, a tablet for oral transmucosal administration. The company also provides Sufentanil NanoTab PCA system, a sublingual patient-controlled analgesia system with a drug/device combination product candidate for the management of acute postoperative pain in hospital settings; Sufentanil NanoTab BTP management systems for the treatment option for patients with cancer pain; and Sufentanil/Triazolam NanoTab, which provides analgesia and sedation for minor outpatient procedures.
RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.
Summit Healthcare REIT is a real estate investment trust that invests in assisted living, memory care, and skilled nursing facilities. Summit's portfolio is diverse in terms of geography as well as top-tier operators.
Evolus medical aesthetics company focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments. They focus on the self-pay aesthetic market and their first product candidate, PrabotulinumtoxinA (DWP-450), is an injectable 900 kDa botulinum toxin type A complex designed to address the needs of the large and growing facial aesthetics market. They believe they will offer physicians and patients a compelling value proposition with DWP-450. Currently, onabotulinumtoxinA (BOTOX) is the neurotoxin market leader and the only known approved 900 kDa botulinum toxin type A complex in the United States. They believe aesthetic physicians generally prefer the performance characteristics of the complete 900 kDa neurotoxin complex and are accustomed to injecting this formulation. We have completed the clinical development program for DWP-450 for the treatment of moderate to severe glabellar lines ("frown lines") between the eyebrows in the US, EU, and Canada. The FDA issued a PDUFA date of May 15, 2018, for completion of its review of our BLA. We submitted an MAA to the EMA and a decision is expected by the second half of 2018. They have also submitted an NDS in Canada. They have an exclusive distribution license to DWP-450 from Daewoong Pharmaceuticals Co.
Continuing Healthcare Solutions is to provide our residents with exceptional care and treat them with the highest levels of dignity and respect. This demands a commitment to building and maintaining a reputation as a preferred provider of healthcare services, hiring, training and retaining quality healthcare professionals and being a leader in our chosen communities.
AliveCor, Inc. is a technology company that develops digital medical-grade electrocardiograms, enabling users to monitor their heart health through mobile devices. Its flagship product, KardiaMobile, provides instant detection of common heart arrhythmias and allows users to track blood pressure and weight, as well as store recorded EKGs. The company also offers KardiaMobile 6L, a six-lead EKG device that allows patients to share detailed readings with their healthcare providers. Additionally, AliveCor has introduced KardiaCare, a digital health subscription service that facilitates the management of heart health at home. Founded in 2010 and headquartered in Mountain View, California, AliveCor is recognized for its pioneering efforts in using machine learning techniques to enhance cardiac care and improve early detection of conditions such as atrial fibrillation.
Karius is a life sciences company focused on generating genomic insights for infectious diseases with a liquid biopsy for infectious diseases. The Karius Test that helps clinicians make rapid, treatment decisions. By mapping each patient’s microbial landscape from a single blood draw, Karius moves closer to a vision of a world where infectious disease is no longer a major threat to human health. The Karius laboratory is CLIA-certified and CAP-accredited to perform high-complexity clinical laboratory testing.
Nevakar is a specialty pharmaceutical company that focuses on the development of innovative products in the injectable and ophthalmic space. Their goal is to develop enhanced products that address unmet clinical and/or commercial needs of currently [FDA] approved molecules, through intensive R&D and clinical efforts. Nevakar’s business model is supported by state-of-the-art R&D infrastructure, located in the NJ Center of Excellence, and a well-experienced management and leadership team.
QuVa Pharma is a pharmaceutical company engaged in the innovation and production of pharmaceutical products. they provide 503B outsourcing, ordering, and consulting services.
Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses a catheter based approach to reshape the mitral valve and reduce mitral regurgitation.
Xeris Biopharma is a specialty pharmaceutical company leveraging its novel formulation technology platforms to develop and commercialize ready-to-use, liquid-stable injectables. The company’s proprietary XeriSol and XeriJect formulation technologies allow for the subcutaneous (SC) and intramuscular (IM) delivery of highly concentrated, non-aqueous, ready-to-use formulations of peptides, proteins, antibodies, and small molecules using syringes, auto-injectors, multi-dose pens, and infusion pumps. Xeris’ platforms have the potential to offer distinct advantages over existing formulations of marketed and development-stage products. In particular, XeriSol and XeriJect offer the opportunity to eliminate reconstitution, enable long-term room temperature stability, significantly reduce injection volume, and eliminate the requirement for intravenous (IV) infusion. These attributes can lead to products that are easier to use by patients, caregivers, and health practitioners and reduce costs for payers and the healthcare system.
VitalConnect develops wearable biosensor technology designed for wireless patient monitoring. It leverages extensive expertise in biomedical engineering, data analytics, chip design, and mobile and cloud software to create technology that supports decision-making paradigms. The company's products are designed for inpatient and outpatient settings, such as hospital monitoring, post-discharge care, cardiac monitoring, and pharmaceutical solutions.
Puma Biotechnology, Inc., is a development stage biopharmaceutical company that acquires and develops innovative products for the treatment of various forms of cancer. The Company focuses on in-licensing drug candidates that are undergoing or have already completed initial clinical testing for the treatment of cancer and then seeks to further develop those drug candidates for commercial use. The Company is initially focused on the development of PB-272 (oral neratinib), a potent irreversible tyrosine kinase inhibitor, for the treatment of patients with HER2 positive metastatic breast cancer.
AirXpanders they designs and manufactures medical devices to improve breast reconstruction.
Castle Biosciences is a biotech company that develops and validates diagnostic tests and technologies for the treatment of cancer. The company also focused on providing physicians and patients with personalized, clinically actionable genomic information to make more accurate treatment plan decisions. The DecisionDx family of molecular diagnostic tests have the ability to meaningfully impact how cancers are diagnosed and managed and the DecisionDx-Melanoma predicts risk of recurrence or metastasis for patients with invasive cutaneous melanoma, a deadly skin cancer, including the risk of sentinel lymph node positivity. Castle Biosciences was founded in 2008 and is headquartered in Friendswood, Texas, United States.
Cerapedics is an orthobiologics company focused on developing its proprietary biomimetic small peptide molecule (P-15) for commercialization in spinal applications. The company was founded in 2001 and is headquartered in Westminster, Colorado.
Reata Pharmaceuticals is a biopharmaceutical company that develops drugs for cancer, inflammation, and neurodegenerative diseases. It offers antioxidant and inflammation-modulating drugs, as well as drugs that correct protein misfolding. The company also develops drugs for the treatment of renal, cardiovascular, and autoimmune diseases. The company was formerly known as Reata Discovery, Inc. and changed its name to Reata Pharmaceuticals, Inc. in May 2005.
Oxford BioTherapeutics (OBT) is focused on the development of targeted medicines in the field of cancer. The company has signed strategic partnerships with the leading antibody companies Medarex, Biosite and Amgen to build a broad pipeline of novel antibody therapeutics using its unique OGAP® (Oxford Genome Anatomy Project) platform. OGAP® is one of the world’s largest proprietary human protein databases which contains and combines proteomic and genomic data with related clinical information. OBT also intends to develop companion diagnostics for selected antibody programmes. The company expects to improve disease management and treatment outcomes by integrating diagnostics into product development and commercialisation activities.
Conformis is a medical technology company that uses its proprietary iFit® Image-to-Implant® technology platform to develop, manufacture, and sell joint replacement implants and instruments that are individually sized and shaped, which it refers to as personalized, individualized, or sometimes as customized, to fit each patient’s unique anatomy. Conformis offers a broad line of sterile, personalized knee and hip implants and single-use instruments delivered to hospitals and ambulatory surgical centers.
Eiger BioPharmaceuticals is a privately held biotechnology company that develops a novel antiviral therapy for Hepatitis Delta, a life-threatening, Orphan Disease with high unmet medical need and no approved therapy. The company is led by a management team experienced in the development and commercialization of rare disease therapeutics. Its strategy is predicated upon time and cost-efficient drug development, with the goal of delivering safe and effective therapies to patients.
Strongbridge Biopharma’s primary focus has been to build its franchise around rare endocrine disorders, which includes product candidates for the treatment of endogenous Cushing’s syndrome and acromegaly, two rare diseases with a high unmet need for innovative treatment options. Given the well-identified and concentrated prescriber base addressing its target markets, the Company intends to use a small, focused sales force to market its products, if approved, in the United States, European Union and other key global markets. The Company intends to identify and in-license or acquire products or product candidates that would be complementary to its existing rare endocrine franchise or that would form the basis for new rare disease franchises.
Veran Medical Technologies is an image-guided medical device company that helps physicians diagnose disease and deliver therapies. It develops a suite of products to enable physicians to diagnose disease and deliver therapies. It offers standards for minimally invasive delivery of interventional oncology therapies. The company provides plug-n-play delivery systems and navigated instruments. Its IG4 Platform allows clinicians to visualize various types of information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound. The company also provides SPiN Drive System that acts as a GPS-like system to enable pulmonologists and surgeons to access peripheral solitary pulmonary nodules to diagnose malignancy. The company was incorporated in 2007 and is headquartered in St. Louis, Missouri.
BiO2 Medical offers Angel Catheter that provides prophylactic Pulmonary Embolism protection and access to the central venous system. It was formerly known as Artificial Airways. Bi02 Medical design, develops, and manufactures medical devices. It develops Angel Catheter, a catheter-based IVC filter for the prevention of pulmonary embolism in critical care patients worldwide. The Angel Catheter allows for insertion and access to the central venous system for administering medications, fluids, or blood products; blood sampling; and monitoring of central venous pressure. The company was founded in 2006 and is based in San Antonio, Texas with a research and development, and manufacturing facility in Golden, Colorado.
CVRx is a medical device company that develops implantable technology for the treatment of high blood pressure. Its products include Rheos implantable pulse generator that provides control and delivery of the activation energy; and Rheos carotid sinus leads, which conducts activation energy from the Rheos implantable pulse generator to the left and right carotid arteries. The company also offers a Rheos programmer system that communicates with the Rheos pulse generator. CVRx was founded in 2001 and is based in Minneapolis, Minnesota.
Senseonics is a medical device startup company in Germantown, Maryland, USA (near Washington, DC) developing transformative glucose monitoring products that is intended to enable people with diabetes to confidently live their lives with ease. Utilizing breakthrough fluorescence sensing technology, the Senseonics continuous glucose monitoring ("CGM") system is being designed to be the first fully implantable CGM that is highly accurate and stable throughout its long sensor life.
Ignyta is a scientifically-driven biotechnology company catalyzing personalized medicine in autoimmune diseases. Their goal is to revolutionize the quality of biomarkers and tests available to rheumatologists and patients to help them make better informed, more individualized treatment decisions; and to identify truly novel autoimmune disease targets for biopharmaceutical companies to enable the development of precise therapies for patients worldwide. Ignyta was incorporated in 2011 and operates in San Diego, California.
Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer. It is a private equity-backed neurosurgical company focused solely on diseases of the brain. It develops MRI-guided, laser-based systems designed for the ablation of brain lesions. The company's system applies focused laser energy to ablate brain tumors from the inside, with little or no effect on surrounding healthy tissue as well as provides clinicians a new neurosurgical tool that offers real-time control and visualization of the therapy during laser ablation treatment, enabling neurosurgeons to ablate (treat with lethal heat) brain lesions and brain tumors that may be difficult to approach via traditional methods. It was founded in 1999 and has offices in Minneapolis, Minnesota, USA and Winnipeg, Manitoba, Canada.
Regulus Therapeutics Is a biopharmaceutical company leading the discovery of a new class of high-impact medicines based on microRNAs. The discovery of MicroRNA in humans is one of the most exciting scientific breakthroughs in the last decade. MicroRNAs are small RNA molecules, typically 20 to 25 nucleotides in length, that do not encode proteins but instead regulate gene expression. It was founded in 2007 and is headquartered in Carlsbad, California.
Omeros is a Seattle-based commercial-stage biopharmaceutical company committed to discovering, developing, and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, complement-mediated diseases and disorders of the central nervous system.
ADMA is a specialty immune globulin company that develops, manufactures and intends to market plasma-based biologics targeted to niche patient populations for the treatment and prevention of certain infectious diseases. The Company’s target patient populations include immune-compromised individuals who suffer from an underlying immune deficiency disease or who may be immune-suppressed for medical reasons. ADMA also operates ADMA BioCenters, FDA-licensed source plasma collection facilities which provide a portion of blood plasma for the manufacturing of the Company’s lead product candidate RI-002.
Nuvectra focuses on the development and commercialization of its neurostimulation technology platform for the treatment of various disorders through stimulation of tissues associated with the nervous system. Its business involves the manufacture of medical devices for chronic neurological conditions.
Superior Biologics is a leading provider of intravenous and injectable medications for patients with chronic disorders. Our mission is to provide cost effective, patient specific services, which offer patients the freedom to lead normal lives and have optimal therapeutic outcomes. We are dedicated to understanding the changing demands of caring for patients with chronic disorders. We respond to the individual needs of patients and their families by providing personal service backed by highly qualified professionals. Superior Biologics is based in Hawthorne, New York (Westchester County), and primarily services the tri-state area of New York, New Jersey and Connecticut. Based on our pharmacy licensure, we are also able to service patients in various other states in addition to this immediate geographic area. Please contact us to find out if we are able to service your area.
BiO2 Medical offers Angel Catheter that provides prophylactic Pulmonary Embolism protection and access to the central venous system. It was formerly known as Artificial Airways. Bi02 Medical design, develops, and manufactures medical devices. It develops Angel Catheter, a catheter-based IVC filter for the prevention of pulmonary embolism in critical care patients worldwide. The Angel Catheter allows for insertion and access to the central venous system for administering medications, fluids, or blood products; blood sampling; and monitoring of central venous pressure. The company was founded in 2006 and is based in San Antonio, Texas with a research and development, and manufacturing facility in Golden, Colorado.
Omeros is a Seattle-based commercial-stage biopharmaceutical company committed to discovering, developing, and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, complement-mediated diseases and disorders of the central nervous system.
Aratana is uniquely positioned to deliver new, high-quality medicines to address unmet needs in companion animal care. We are committed to bringing world class science to animal health for companion animals and the people who care for them. Our competitive advantage resides in our ability to identify, acquire and develop high-value commercial products for companion animals in a cost effective and efficient manner.
MDRejuvena is dedicated to and passionate about providing products that rejuvenate, enhance, and maintain skin health for the patients of physicians and skincare professionals worldwide. It specializes in the fields of fitness, healthcare, and wellness. It was founded in 2015 and headquartered in San Diego, California.
Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems. In addition to the SImmetry Sacroiliac Joint Fusion System, the company is also developing the Glyder Facet Restoration Device. Zyga has put together a team of engineers, marketing personnel, and management with significant experience developing medical devices for the spine industry. Zyga Technology was founded in 2008 and is headquartered in Minnesota, USA.
Continuum Health Alliance, LLC ("Continuum") is a regional healthcare management company founded in 1998 by nationally-renowned pediatrician John M. Tedeschi, MD. Continuum offers operational oversight and optimizes business processes, enabling physician groups and hospitals to better serve their patients. The Company's comprehensive service portfolio is built on five pillars. Continuum offers administrative solutions, financial services, revenue cycle management, information technology, and population management services, which addresses new governmental guidelines and healthcare initiatives. Continuum also collaborates with hospitals to create and manage medical group networks, hospitalist programs, and innovative hospital-based programs; and helps medical providers navigate and respond to the regulatory requirements mandated by America's health care reform legislation. The Company presently oversees an aggregate client workforce of more than 4,000 employees located in approximately 200 medical offices and hospital settings
Venus Concept is a progressive-thinking company driven by their passion to create cutting-edge technologies and products. While resting on strong ethical morals, they push boundaries in order to create new standards in the medical aesthetics industry. Led by a team of experienced executives and researchers, world renowned for their achievements in the medical aesthetics industry, Venus Concept is delivering on the promise of a more effective, more pleasant, and more profitable experience.
Ocera is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for patients with acute and chronic liver disease, an area of high unmet medical need. Ocera's HE clinical development efforts include a recently completed Phase 2b clinical trial, STOP-HE, which evaluated the safety and efficacy of intravenously-administered OCR-002 in resolving neurocognitive symptoms of acute HE in hospitalized patients with elevated ammonia. Ocera is preparing to meet with the FDA later this year to review the IV program and discuss potential development paths forward.
AlterG is a company researching pressure-unweighting technology in producing Anti-Gravity Treadmill™ for physical therapy and training.
ADMA is a specialty immune globulin company that develops, manufactures and intends to market plasma-based biologics targeted to niche patient populations for the treatment and prevention of certain infectious diseases. The Company’s target patient populations include immune-compromised individuals who suffer from an underlying immune deficiency disease or who may be immune-suppressed for medical reasons. ADMA also operates ADMA BioCenters, FDA-licensed source plasma collection facilities which provide a portion of blood plasma for the manufacturing of the Company’s lead product candidate RI-002.
Labcyte Inc. is a laboratory instrumentation company with a novel approach to dispensing small volumes of liquids for life sciences applications. The company's acoustic dispensing technology uses a focused beam of acoustic energy to eject nanoliter-scale droplets of fluid from one plate to another, with high accuracy at low volumes and reduced consumables costs. In addition to DBL Investors, investors include Alloy Ventures, Abingworth, New Leaf Venture Partners, and Cross Atlantic Partners. Labcyte was founded in 2000 and is based in San Jose, California, United States.
Edgemont’s Management Team and Board of Directors have extensive experience and a proven track record of success in the pharmaceutical industry and the field of life sciences. Click on a link above or scroll down to learn more about the Edgemont leadership team.
Celula, Inc. is a diagnostic testing services company focused on significantly improving the accuracy of diagnosing major diseases, enabling better patient care and improved outcomes. Celula’s unique cost effective “Integrated Diagnostic Accuracy” platform (IDA) consists of algorithmically combining proprietary technologies and non-proprietary technologies that together achieve significantly greater accuracy compared to current tests. The IDA test results have the potential to achieve a much higher positive predictive value (PPV) for presence of disease and greatly decrease unnecessary interventions caused by false positive results. The actionable results will be delivered in a customized Integrated Patient Report (IPR) that facilitates decision making for both the patient and the physician. The company’s initial products will focus on improving the diagnostic accuracy of major women’s diseases, specifically in gynecologic cancers and non-invasive prenatal diagnosis. Celula has an established infrastructure in both the U.S. and China allowing it to develop new products in a significantly more capital efficient manner as well as expand its commercial opportunities beyond the U.S. The company is headquartered in San Diego, California and has development facilities in Chengdu, China.
ReShape Medical Inc. is a medical device company specializing in non-surgical weight loss solutions for individuals with mild to moderate obesity, specifically those with a Body Mass Index (BMI) of 30-40. The company offers the ReShape procedure, which utilizes a dual intragastric balloon system combined with a personalized one-year weight loss program, aimed at facilitating weight loss through lifestyle changes. This procedure is designed for adult patients who have not achieved success with diet and exercise alone. ReShape Medical operates through medical weight loss centers and is based in San Clemente, California. Originally founded as Abdominis, Inc. in 2005, the company was rebranded and operates as a subsidiary of ReShape Lifesciences Inc. The broader product portfolio of its parent company includes other minimally invasive devices for treating obesity and metabolic diseases.
Inhibrx is a clinical-stage biotechnology company focused on developing a broad pipeline of novel biologic therapeutic candidates. Inhibrx utilizes diverse methods of protein engineering to address the specific requirements of complex target and disease biology, including its proprietary sdAb platform. The Inhibrx pipeline is focused on oncology, orphan diseases, and infectious diseases. Inhibrx has collaborations with Celgene and Bluebird Bio and has received awards from several granting agencies, including NIH, NIAID, and CARB-X.
InterValve Inc. develops medical devices/technology for the catheter-based treatment of calcified aortic valve stenosis. It develops tools for the percutaneous and trans-apical aortic valve replacement procedure. The company was founded in 2008 and is based in Minnetonka, Minnesota.
Minerva Neurosciences is a clinical-stage biopharmaceutical company focused on the development and commercialization of a portfolio of product candidates to treat central nervous system (CNS) diseases. Our goal is to transform the lives of patients with improved therapeutic options and a patient-centric focus. Leveraging extensive domain expertise, we have identified and acquired or in-licensed a portfolio of development-stage proprietary compounds with innovative mechanisms of action.
Asensus Surgical is a digital interface between the surgeon and patient to improve minimally invasive surgery through digital laparoscopy. They enable capabilities such as augmented intelligence, connectivity, and robotics in laparoscopy and seek to address the current clinical, cognitive, and economic shortcomings in surgery.
Trevena is a privately held clinical stage biopharmaceutical company based in King of Prussia, PA, dedicated to the discovery and development of GPCR biased ligands. Established in late 2007, Trevena was created to translate groundbreaking research on GPCR signaling into a new generation of medicines. They have three programs in development: TRV027, currently in phase 2 clinical testing for the treatment of acute heart failure; TRV130, currently completing phase 1 testing for the intraveneous treatment of postoperative pain; and TRV734, currently in pre-clinical testing for oral treatment of acute and chronic pain. In addition, Trevena has built an early-stage portfolio of drug discovery programs currently in lead optimization. G protein coupled receptors are the targets for more than 30% of all currently marketed therapeutics. There is significant opportunity to improve upon currently marketed GPCR drugs because many have limited efficacy and undesirable adverse effects, which can prevent broader use. Furthermore, many GPCRs are linked to diseases but cannot be translated into medicines because of specific target-related adverse effects. Trevena's biased ligand approach has the potential to address these problems across a wide range of receptors and therapeutic areas.
Pulmonx is the global leader in interventional procedures for the treatment of COPD. It develops and markets non-surgical technologies for the assessment and treatment of patients with severe emphysema, a progressive and life-threatening form of COPD. The Pulmonx solution, which is comprised of the Zephyr Endobronchial Valve (Zephyr Valve), the Chartis Pulmonary Assessment System (Chartis System) and the StratX Lung Analysis Platform, is designed to treat severe emphysema patients who, despite medical management, are still profoundly symptomatic and either do not want or are ineligible for surgical approaches. The technology is supported by a compelling body of clinical evidence including over 100 published scientific articles regarding the clinical benefits of Zephyr Valves. FDA granted the Zephyr Valve a ‘breakthrough device’ designation, and in June 2018 Pulmonx received FDA pre-market approval to commercialize our Zephyr Valve. The Zephyr Valve is now commercially available and physicians in more than 25 countries around the world routinely use the Zephyr Valves to improve the lives of patients with severe emphysema, with over 76,000 valves used to treat more than 19,000 patients worldwide to date.
HTG Molecular Diagnostics is a provider of molecular-based technology solutions for gene expression profiling, miRNA, siRNA and mRNA measurement for translational medicine and diagnostic applications. The Company's NGS-adapted chemistry and HTG EdgeSeq technology automate sample processing and can swiftly, reliably, and concurrently profile hundreds or thousands of molecular targets utilizing a very little quantity of biological material, in liquid or solid form. Its products comprise equipment, consumables, and software that work together to form the HTG EdgeSeq platform. The HTG EdgeSeq platform automates the company's menu of HTG EdgeSeq molecular profiling panels, which use genomic sequencing techniques to swiftly provide gene expression data for clients utilizing its streamlined approach. HTG Molecular Diagnostics was established in 1997 by Bruce E. Seligmann in Tucson, Arizona.
diaDexus is a privately held biotechnology company that is focused on the discovery, development and commercialization of novel, patent protected diagnostic products with high clinical value. The company's lead product, the PLAC Test, measures Lp-PLA2 (lipoprotein-associated phospholipase A2) a vascular-specific inflammatory enzyme implicated in the formation of rupture-prone plaque. It is plaque rupture and thrombosis, not stenosis, that cause the majority of cardiovascular events. The PLAC Test is the only blood test cleared by the FDA as an aid in assessing risk for coronary heart disease, and ischemic stroke associated with atherosclerosis.
Tarsa Therapeutics is developing an oral formulation of calcitonin, a peptide hormone for the treatment of osteoporosis that slows the rate of bone destruction.
Cardiff Oncology is a clinical-stage oncology therapeutics company developing drugs that target cell division for the treatment of leukemias, lymphomas, and solid tumor cancers. It has a broad intellectual property and proprietary technology to measure circulating tumor DNA (ctDNA) in urine and blood to identify and quantify clinically actionable markers for predicting response to cancer therapies. The company offers its PCM technology at its CLIA/CAP-accredited laboratory and plans to continue to vertically integrate its PCM technology with precision cancer therapeutics. Cardiff Oncology (formerly known as Trovagene) was founded in 1999 and is headquartered in San Diego, California.
Cerus Corporation is a biomedical products company focused in the field of blood safety. Cerus currently markets and sells the INTERCEPT Blood System for both platelets and plasma in Europe, the Commonwealth of Independent States, the Middle East and selected countries in other regions around the world. In the United States, Cerus is seeking regulatory approval of the INTERCEPT Blood System for plasma and platelets. The INTERCEPT red blood cell system is in clinical development.
Tobira Therapeutics, Inc. is a biotechnology company focused on the research, development, and commercialization of antiviral compounds aimed at treating serious infectious diseases. Founded in 2006 and based in Princeton, New Jersey, the company specializes in the development of TBR-652 and TBR-220 antagonists, which are designed for the treatment of HIV/AIDS, hepatitis, and other related infectious conditions. Through its innovative approach, Tobira Therapeutics aims to address critical health challenges associated with these diseases.
DURECT is a specialty pharmaceutical company developing innovative drugs for pain and chronic diseases, with late-stage development programs including REMOXY®, POSIDUR™, ELADUR®, and TRANSDUR®-Sufentanil. DURECT’s proprietary oral, transdermal and injectable depot delivery technologies enable new indications and superior clinical/commercial attributes such as abuse deterrence, improved convenience, compliance, efficacy and safety for small molecule and biologic drugs
IntelliCyt Corporation develops cell- and bead-based screening solutions using high throughput flow technology for use in drug discovery, antibody discovery, and immunology. It provides iQue Screener platform, an integrated instrument, software, and reagent system that enables high-content multiplexed analysis of cell- and bead-based samples in liquid suspension; ForeCyt software, an intuitive workflow-based environment for data visualization, instrument control, and data analysis; and MultiCyt screening kits–cell and bead-based reagents for use on iQue Screeners. The company also offers installation, training, technical support, and repair services. Its products are used in laboratories at pharmaceutical companies, biotechnology companies, and medical centers worldwide. IntelliCyt Corporation was formerly known as Sage Sciences, Inc. The company was founded in 2006 and is based in Albuquerque, New Mexico. As of June 28, 2016, IntelliCyt Corporation operates as a subsidiary of Sartorius AG.
Relypsa is a biotech company. They discover and develop non-absorbed polymeric drugs for applications in cardiovascular and renal diseases. They specialize in iron deficiency, nephrology, and cardio-renal therapies.
Ceterix Orthopaedics, Inc. develops novel surgical tools for arthroscopic procedures. The Ceterix technology enables surgeons to place stitches in very tight joint compartments, while protecting sensitive surrounding structures such as nerves, arteries and cartilage. This technology has applications in numerous arthroscopic procedures in knees, hips and shoulders. Ceterix was established in October 2010. The company was founded based on the inventions of Dr. Justin Saliman, an orthopaedic surgeon specializing in sports medicine. Dr. Saliman envisioned improving the outcomes of arthroscopic procedures by enabling surgeons to place suture patterns that today can be done only in open procedures, if at all. Ceterix is based in Menlo Park, California.
Conventus Orthopaedics provides a range of orthopedic and sports medicine services. The physicians specialize in orthopedic surgery, reconstructive surgery, spine surgery, joint replacement, sports medicine, physical therapy, and operative care of fractures, arthritis, strains, sprains, and sports-related injuries. Conventus was formed by a team of medical professionals with the sole purpose of creating less invasive ways to treat challenging periarticular fractures. By leveraging advanced nitinol technology, the Conventus team has developed a platform technology that provides robust fixation and creates reliable repairs. The company was incorporated in 2009 and is based in Maple Grove, Minnesota.
RF Surgical Systems, Inc. is the market leader in the detection and prevention of retained surgical sponges. The RF Surgical Detection System is the preferred solution in more than 1,500 operating rooms, trauma and labor and delivery suites nationwide. Since January 2011, more than 70 hospitals and surgical centers have joined the fast-growing list of care providers using RF Surgical Technology. RF Surgical Systems is based in Bellevue, Washington with R & D facilities in San Diego, California. The advanced technologies used in the RF Surgical Detection System are protected by U.S. patents. Regulatory clearance to market the system was granted by the U.S. Food and Drug Administration in November 2006.