Région Sud Investissement

Founded in 2010, Région Sud Investissement is a venture capital firm based in Marseille, France. It provides venture capital investments, participatory loans, and convertible loans to startups across France with a focus on the South Region.

Pierre Joubert

CEO

50 past transactions

Circle Safe

Venture Round in 2025
Circle Safe is a medical technology company focused on enhancing the safety of cardiac ablation procedures for atrial fibrillation. Their primary product is a device designed to prevent diaphragmatic paralysis, a complication specific to cryoballoon ablation techniques. By addressing this key safety concern, Circle Safe's technology enables electrophysiologists to perform procedures with increased confidence, potentially improving patient outcomes and broadening the adoption of this life-saving treatment.

HEXANA

Seed Round in 2025
HEXANA develops an energy platform that integrates sodium-cooled fast-neutron reactors with a thermal management system and high-temperature storage to deliver flexible on-demand electricity and process heat while reducing nuclear waste. The modular reactors are designed for both on-site and grid-scale deployment, enabling flexible power production and direct industrial heat applications with emphasis on safety and waste management.

Interactive Autonomous DYnamic Systems

Series A in 2024
Iadys designs, develops, and delivers robotic and AI innovations aimed at environmental preservation. The company's flagship product, the Jellyfishbot, is a robot that collects floating waste and oil in water bodies and performs underwater measurements. Iadys also offers the Mobile Oil Skimmer, which is used for oil spill response. These products are designed to access and clean hard-to-reach areas, contributing to cleaner and safer aquatic environments.

Trust-Place

Seed Round in 2024
Trust-Place develops a digital identity platform that enables brands to authenticate items with digital certificates of ownership. This enhances product value, tracks history, facilitates transfers, and connects brands with their customers.

Eyco

Series A in 2024
Eyco is a manufacturer specializing in the design and production of smart circuits and hardware elements for the digital applications sector. Operating within the European microelectronics industry, the company focuses on creating innovative industrial machinery that minimizes environmental impact. By ensuring efficient mass production tailored to client specifications, Eyco enables secure digital applications while promoting sustainability in technology. Its commitment to advancing the high-tech ecosystem of electronics positions Eyco as a key player in the development of environmentally responsible solutions in the digital landscape.

Wise Integration

Series B in 2024
Wise Integration is a developer of GaN-integrated solutions to miniaturize power supplies and improve energy efficiency.

ACWA Robotics

Seed Round in 2024
ACWA Robotics specializes in developing autonomous, amphibious robots designed to inspect and map water pipelines globally. Their devices navigate through pipes, providing precise data on their condition, enabling clients to plan maintenance and prevent leaks more effectively.

Nexess

Venture Round in 2024
Founded in 2006, Nexess specializes in developing and selling advanced security management solutions for nuclear and high-risk industrial plants. Its product portfolio includes RFID tags, smart cameras, antenna systems, and software platforms designed to enhance traceability, productivity, and security. Headquartered in Mougins, France, with an additional office in Paris, the company serves clients aiming to improve their operational efficiency and safety.

Lanteas

Venture Round in 2023
Lanteas specializes in providing open-source Customer Relationship Management (CRM) solutions tailored for public actors. They offer innovative platforms such as GRU (User CRM), Open Sub, Open Childhood, and Open Colleges & Lycees. Lanteas also integrates the GRU Capdemat Evolution solution into its comprehensive customer CRM packages for local and regional authorities.

Ixcys

Venture Round in 2023
Ixcys is a technology company that offers advice, services, and development solutions. It specializes in creating and implementing online development strategies, personalized digital applications, and connected management systems.

BiOceanOr

Venture Round in 2023
BiOceanOr specializes in underwater weather stations designed to monitor water quality in real-time. Their solutions provide immediate alerts for informed decision-making.

Pess Energy

Series A in 2023
Pess Energy designs, manufactures, and markets zero-emission generator sets with large capacities and powers.

Ilios International

Seed Round in 2023
Ilios International is a global security company specializing in travel risk management. It offers a digital SaaS platform providing real-time risk alerts, travel monitoring, crisis management support, and local emergency response services to ensure the safety of employees during business travels.

Pulpe de Vie

Venture Round in 2023
Pulpe de Vie is an organic and ethical beauty company that develops and sells skincare cosmetics made from unsold fruits sourced from small local producers, prioritizing environmental responsibility and affordability for sensitive skin.

Futura gaia

Series A in 2023
Futura gaia offers processes from seed and seedling selection to bio-stimulation, minerals, and traceability. They also provide solutions for industries such as food distribution, HRD, cosmetics, and pharmaceuticals. The company's contact modes are phone and physical address.

HSL Technologies

Series A in 2023
HSL Technologies develops hydrogen solutions focusing on safe transport, storage, and on-demand generation. Its HydroSil-based technology enables hydrogen to be moved through conventional infrastructure with reduced risk, supporting scalable delivery and storage. The company also engineers hydrogen generation technology that produces hydrogen on demand through a controlled reaction between two stable liquids, enabling safe transport and storage at ambient temperature and pressure. By delivering energy-dense, adaptable hydrogen options, HSL Technologies addresses logistical challenges tied to traditional storage and supports the transition to low-carbon energy systems.

Mycophyto

Venture Round in 2023
Mycophyto, co-founded in July 2016 by Justine Lipuma, a microbiology PhD, and Christine Poncet-Doiset, a Senior Research Engineer at INRA, focuses on innovative solutions for agricultural systems. Drawing on 30 years of research in biological crop protection, the company specializes in developing customized products and support services aimed at enhancing plant growth through the use of indigenous fungi and soil pathogens. Mycophyto operates an inbuilt greenhouse where it cultivates these beneficial microorganisms, allowing plant researchers to cultivate crops, herbs, and other plants without reliance on chemical fertilizers. This approach not only promotes sustainable agricultural practices but also contributes to healthier ecosystems.

K-Motors

Seed Round in 2022
K-Motors specializes in enhancing electric vehicle performance through its innovative greenboost solution. This plug-and-play buffer storage system increases power, autonomy, and battery life for any electric vehicle.

Butterfly Job

Pre Seed Round in 2022
Butterfly Job is an innovative SaaS-based recruitment platform that aims to guide candidates towards their dream job. At Butterfly Job, we are determined to revolutionize recruitment for both candidates and companies. That's why we have developed cutting-edge technology to provide a personalized and innovative recruitment experience through our Adaptive Intelligence Matching Engine (AMIE) application. With AMIE, you will have a unique recruitment experience. Built on neural network algorithms and social psychology research, AMIE learns from each user interaction to continuously refine its relevance month after month. This constantly evolving technology adapts to the changing expectations of candidates and companies, offering you a personalized and innovative recruitment experience. Don't wait any longer to join the recruitment revolution and take advantage of the benefits of our constantly improving application.

GoMecano

Seed Round in 2022
GoMecano operates a platform that facilitates interactions between mobile mechanics and customers for vehicle repair and maintenance services at competitive prices. The platform enables customers to select mechanics based on community reviews, eliminating additional travel costs.

Hoopiz

Venture Round in 2022
Hoopiz offers management of payment reminders, collections, credit checking, and credit insurance. Their platform provides customer follow-up, recovery, follow-up management, management of late payments and bad debts, and accounts receivable services.

Therapixel

Series B in 2022
Therapixel develops and commercializes AI-based medical imaging software for surgeons, focusing on breast cancer detection and characterization and intraoperative image management. The company designs image analytics tools that enable clinicians to access and interpret medical images before or during procedures while maintaining sterility through touchless interfaces. Its product family includes Radvise, an automatic image reading solution; Fluid, a touchless medical image navigation system for surgery; Anywhere, a post-processing workstation; and CD-Feed, a CD import solution for outpatient imaging exams. Founded in 2013 and headquartered in Valbonne, France, Therapixel operates globally with a presence in multiple countries, supporting surgeons with timely, decision-ready imaging information.

Miratlas

Seed Round in 2022
Miratlas designs and manufactures instrumentation to measure atmospheric conditions in real-time. Their devices enhance understanding of climate change and optimize free-space optical communications.

Cintoo

Series A in 2022
Cintoo is a technology company focused on managing and utilizing 3D data derived from Reality Capture devices in the cloud. It has developed a unique point cloud-to-surface technology that converts data from terrestrial laser scanners into a versatile and collaborative format known as Reality Data. This innovative technology is integrated into Cintoo Cloud, a cloud-based platform that is compatible with various laser scanning hardware and Building Information Modeling (BIM) systems. By bridging the gap between reality capture and digital twins, Cintoo's platform enhances efficiency for companies in the construction industry, facilitating improved planning and management of buildings and infrastructure.

NAWA Technologies

Series C in 2022
NAWA Technologies specializes in developing advanced energy storage solutions, focusing on its innovative Ultra Fast Carbon Battery Technology. Founded in April 2013 and supported by over 15 years of research and development in nanomaterials, the company aims to enhance energy conversion, storage, transport, and efficiency using carbon, which is abundant and environmentally friendly. NAWA Technologies creates ultracapacitors and battery electrodes that facilitate the integration of renewable energies into smart grids, thus promoting more efficient and sustainable electricity storage. The company is committed to minimizing the environmental impact of its manufacturing processes and emphasizes the importance of reusing, recovering, and recycling materials throughout the product lifecycle. With a dedicated team of 24 employees, NAWA Technologies operates a pilot production line to innovate new interface materials and storage devices that reduce carbon emissions and reliance on fossil fuels.

Tetraneuron

Debt Financing in 2021
Tetraneuron is a gene therapy biotechnology company focused on Alzheimer’s disease. It develops multifactorial gene therapies intended to treat Alzheimer's and to support early detection through associated biomarkers. The company’s therapy employs a neural tetraploidization approach designed to counteract changes linked to E2F4 in blood serum, with the aim of enabling faster recovery for patients. By pursuing both disease modification and early diagnosis, Tetraneuron seeks to advance therapeutic options for Alzheimer's disease.

Universal Beauty Group

Venture Round in 2021
Founded in 2008, Universal Beauty Group is based in Saint-Rémy-de-Provence, France with an additional office in Hong Kong. The company specializes in the creation and distribution of natural cosmetics under its brand Végétalement Provence, catering primarily to beauty professionals. Its product range includes organic hair care products, styling aids, hair accessories, spa products, body care items, makeup brushes, and travel packs.

YouStock

Venture Round in 2021
YouStock provides a full-service storage solution that collects, packs, stores, and delivers customers’ belongings. The company schedules pickups online, employs professional movers for packing and transport, and stores items in secure warehouses with online inventory so customers can manage and track their belongings. Items can be retrieved fully or partially within 24 hours, and pricing is based on the amount stored, with customers paying only for what they store. The service is positioned as a convenient, affordable alternative to traditional self-storage, combining doorstep pickup and delivery with managed storage to simplify relocation and decluttering for individuals.

Rofim

Series A in 2021
Rofim is a company that operates a multidisciplinary eDiagnostic platform designed to enhance the sharing of clinical and patient-related data among healthcare professionals and patients. The platform enables real-time access to clinical descriptions and medical imaging, facilitating effective communication and collaboration between doctors and patients. Rofim focuses on creating tools for secure data exchange and file-sharing, allowing healthcare providers to organize health information and offer consultations remotely. By concentrating on the functionalities that support fluid medical use, Rofim aims to improve the daily lives of physicians, patients, and medical institutions, ensuring timely and accurate diagnoses while promoting ethical practices in healthcare.

Ombrea

Venture Round in 2021
Ombrea is a French company based in Aix-en-Provence, focused on developing climate-control solutions for crops sensitive to weather fluctuations. Founded in 2016 and previously known as Agrivolta SA, Ombrea has created an automated intelligent shade system that uses artificial intelligence to adapt to the specific needs of various crops. This innovative tool collects real-time weather data through installed sensors and creates a microclimate above the fields, helping farmers to mitigate the impacts of climate change and maintain production yields. By providing a means to protect crops from adverse weather conditions, Ombrea supports sustainable agricultural practices in an era of global warming.

Interactive Autonomous DYnamic Systems

Seed Round in 2021
Iadys designs, develops, and delivers robotic and AI innovations aimed at environmental preservation. The company's flagship product, the Jellyfishbot, is a robot that collects floating waste and oil in water bodies and performs underwater measurements. Iadys also offers the Mobile Oil Skimmer, which is used for oil spill response. These products are designed to access and clean hard-to-reach areas, contributing to cleaner and safer aquatic environments.

TrucksMe

Debt Financing in 2021
TrucksMe is an online marketplace for renting trucks. They offer services on digital platforms called truck manager for fleet management, business software, accounting, and maintenance.

DigitecPharma

Venture Round in 2021
DigitecPharma is a company that specializes in developing advanced technology solutions for independent pharmacies and pharmacy groups. It offers a mobile application designed to support the evolving role of dispensary pharmacists. This innovative application, coupled with a responsive website, allows pharmacies to customize their communication strategies and brand initiatives. By providing these tools, DigitecPharma enables pharmacies to enhance their service offerings and adapt to the changing landscape of the pharmaceutical profession.

Tchek

Seed Round in 2021
Tchek is a French startup focused on vehicle inspection, utilizing artificial intelligence to enhance automotive diagnostics. The company has developed an AI-powered system that includes a scanner and an intuitive digital platform, enabling comprehensive analysis of a vehicle's condition. This technology identifies and catalogs damage to the bodywork while quantifying necessary repairs. Tchek's solutions are particularly valuable for dealerships and vehicle owners, as they provide real-time insights into the condition of both domestic and commercial fleets, helping to prevent unnecessary repair costs and ensuring better management of vehicle maintenance.

InnoSkel

Series A in 2020
InnoSkel is a biotechnology company focused on developing therapies for rare skeletal diseases, including collagenopathies that cause skeletal dysplasia. Its lead gene therapy asset targets Spondyloepiphyseal Dysplasia congenita, one of the most severe forms of these conditions, and has shown proof-of-concept efficacy. The company aims to improve quality of life for patients affected by skeletal dysplasia through transformative treatments. It is a spin-out of Institut de Biologie Valrose at Inserm and is based in Nice, France.

MyDataModels

Seed Round in 2020
MyDataModels is a technology company that specializes in developing TADA, an AI-driven analytics platform designed for professionals across various industries. TADA enables users to extract valuable insights from their data and harness the power of machine learning without requiring extensive data science expertise. The platform is particularly beneficial in sectors where data may be underutilized, such as manufacturing, medical research, supply chain, and production, as well as in research and development. By simplifying the process of building and running custom predictive models, MyDataModels allows organizations to optimize their operations, make informed predictions, and derive actionable insights from their data efficiently and affordably.

Perspective(S)

Series A in 2020
Perspective(S) is an IT company. The company specializes in offering tailor-made interactive 3D products that control the entire production chain through a proprietary multimedia engine. They provide game development, 3D visualization, post-production, system and hardware programming, web programming, and modeling.

BiOceanOr

Venture Round in 2020
BiOceanOr specializes in underwater weather stations designed to monitor water quality in real-time. Their solutions provide immediate alerts for informed decision-making.

humanroads

Venture Round in 2020
humanroads collects, analyzes and graphically restores all data related to the academic and professional career of students and Alumni. Through two complementary platforms, humanroads is revolutionizing educational and professional guidance. humanroads is THE solution for visualizing the academic, professional and geographic situations of students and Alumni, before, during and after their training.

NAWA Technologies

Venture Round in 2020
NAWA Technologies specializes in developing advanced energy storage solutions, focusing on its innovative Ultra Fast Carbon Battery Technology. Founded in April 2013 and supported by over 15 years of research and development in nanomaterials, the company aims to enhance energy conversion, storage, transport, and efficiency using carbon, which is abundant and environmentally friendly. NAWA Technologies creates ultracapacitors and battery electrodes that facilitate the integration of renewable energies into smart grids, thus promoting more efficient and sustainable electricity storage. The company is committed to minimizing the environmental impact of its manufacturing processes and emphasizes the importance of reusing, recovering, and recycling materials throughout the product lifecycle. With a dedicated team of 24 employees, NAWA Technologies operates a pilot production line to innovate new interface materials and storage devices that reduce carbon emissions and reliance on fossil fuels.

C4Diagnostics

Venture Round in 2020
C4Diagnostics is a developer of in vitro diagnostic (IVD) kits that leverages proprietary technology to enhance the speed and sensitivity of diagnostic testing. The company focuses on creating medical devices and equipment that streamline the screening process for urinary tract infections, allowing for the reliable detection, counting, and concentration of relevant microorganisms in clinical microbiology. By enabling hospitals and laboratories to conduct culture-based IVD tests and specific fluorescence assessments, C4Diagnostics contributes to more efficient and effective diagnostic practices in healthcare settings.

Gojob

Venture Round in 2020
Gojob is a workforce-as-a-service platform that uses its own technology and data to fluidify the labor market and connect job seekers with opportunities. The platform offers temporary assignments and acts as an intermediary between workers and companies, enabling flexible staffing and placements across sectors such as logistics, construction, manufacturing, sales, services, administration, management, and transportation.

Mycophyto

Seed Round in 2019
Mycophyto, co-founded in July 2016 by Justine Lipuma, a microbiology PhD, and Christine Poncet-Doiset, a Senior Research Engineer at INRA, focuses on innovative solutions for agricultural systems. Drawing on 30 years of research in biological crop protection, the company specializes in developing customized products and support services aimed at enhancing plant growth through the use of indigenous fungi and soil pathogens. Mycophyto operates an inbuilt greenhouse where it cultivates these beneficial microorganisms, allowing plant researchers to cultivate crops, herbs, and other plants without reliance on chemical fertilizers. This approach not only promotes sustainable agricultural practices but also contributes to healthier ecosystems.

Active Asset Allocation

Venture Round in 2019
Active Asset Allocation specializes in providing institutional investors with advanced asset allocation strategies focused on risk management. By actively managing downside risk, the company aims to preserve long-term financial resources responsibly.

My Coach Football

Series A in 2019
My Coach Football allows you to manage and organize the daily operations of your football team, day after day, season after season. Designed to answer amateur and professional coaches’ needs, the platform centralizes all of your squad’s information and allows to gain time and efficiency. In a single click, you can manage players and their personal information, the preparation of training and games, but also individual and collective statistics. Season after season, you keep all those data and hence enjoy an optimum tracking of your team’s progression.

NAWA Technologies

Venture Round in 2019
NAWA Technologies specializes in developing advanced energy storage solutions, focusing on its innovative Ultra Fast Carbon Battery Technology. Founded in April 2013 and supported by over 15 years of research and development in nanomaterials, the company aims to enhance energy conversion, storage, transport, and efficiency using carbon, which is abundant and environmentally friendly. NAWA Technologies creates ultracapacitors and battery electrodes that facilitate the integration of renewable energies into smart grids, thus promoting more efficient and sustainable electricity storage. The company is committed to minimizing the environmental impact of its manufacturing processes and emphasizes the importance of reusing, recovering, and recycling materials throughout the product lifecycle. With a dedicated team of 24 employees, NAWA Technologies operates a pilot production line to innovate new interface materials and storage devices that reduce carbon emissions and reliance on fossil fuels.

Emki Pop

Seed Round in 2019
Emki Pop SAS is a producer and distributor of artisanal ice creams and popsicles based in Aubagne, France. Founded in 2016 and headquartered in Marseille, the company specializes in creating a variety of ice cream bars made exclusively from fresh and natural ingredients. Its product offerings include diverse flavors such as green kiwi, pear, lemon, apple and pear, milk chocolate, dark chocolate, almond, raspberry, strawberry, and apricot. Emki Pop sells its products through physical stores and an online platform, catering to food enthusiasts who wish to indulge in nostalgic ice cream treats.

Therapixel

Series A in 2019
Therapixel develops and commercializes AI-based medical imaging software for surgeons, focusing on breast cancer detection and characterization and intraoperative image management. The company designs image analytics tools that enable clinicians to access and interpret medical images before or during procedures while maintaining sterility through touchless interfaces. Its product family includes Radvise, an automatic image reading solution; Fluid, a touchless medical image navigation system for surgery; Anywhere, a post-processing workstation; and CD-Feed, a CD import solution for outpatient imaging exams. Founded in 2013 and headquartered in Valbonne, France, Therapixel operates globally with a presence in multiple countries, supporting surgeons with timely, decision-ready imaging information.

Whoog

Venture Round in 2014
Whoog SAS is a company that specializes in developing a mobile application designed to enhance operational efficiency in the healthcare sector. The application facilitates the coordination of staff during business emergencies by automatically identifying and dispatching replacements or additional employees as needed. It allows healthcare professionals and voluntary temporary workers to indicate their available services and skill sets, enabling hospitals to quickly assemble reinforcement teams for both last-minute and planned staffing needs. By streamlining internal coordination and improving crisis management, Whoog aims to mitigate productivity disruptions in medical environments and enhance patient care.

VigiZen

Debt Financing in 2013
VigiZen is a company that specializes in developing mobile applications and web services aimed at enhancing the digitization of various processes. Through its innovative solutions, VigiZen focuses on tapping into underserved markets by providing tools that simplify tasks and improve efficiencies. The company offers a digital contracts application that modernizes the contract management process by eliminating paperwork and allowing users to edit, sign, and convert contracts to PDFs using a tablet. Additionally, VigiZen’s services include large-format shared tablet solutions designed for senior residences, facilitating connections between family members and clients. The company is also engaged in research and development in advanced technologies, such as blockchain, machine learning, and image processing, to further enhance its applications and services.
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